locus-tag	class	description
FE36_00010	COG1064	alcohol dehydrogenase
FE36_00015	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
FE36_00020	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
FE36_00025	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
FE36_00035	COG2234	aminopeptidase activity
FE36_00045	COG4942	peptidase
FE36_00050	COG0793	Belongs to the peptidase S41A family
FE36_00095	COG1304	FMN binding
FE36_00105	COG1657	PFAM Prenyltransferase squalene oxidase
FE36_00110	COG0142	geranyltranstransferase activity
FE36_00115	COG2124	cytochrome p450
FE36_00120	COG1028	Short-chain dehydrogenase reductase Sdr
FE36_00125	COG1141	Ferredoxin
FE36_00130	COG2124	cytochrome p450
FE36_00135	COG2124	cytochrome p450
FE36_00205	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FE36_00210	COG1074	ATP-dependent DNA helicase activity
FE36_00215	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
FE36_00250	COG1127	ABC transporter
FE36_00255	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FE36_00260	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FE36_00275	COG2853	Lipoprotein
FE36_00280	COG0386	Belongs to the glutathione peroxidase family
FE36_00290	COG1322	Protein conserved in bacteria
FE36_00300	COG0531	amino acid
FE36_00305	COG0493	'glutamate synthase
FE36_00310	COG0069	glutamate synthase activity
FE36_00310	COG0070	glutamate synthase
FE36_00310	COG0067	glutamate synthase
FE36_00370	COG1111	helicase
FE36_00370	COG1205	dead DEAH box helicase
FE36_00375	COG1272	protein, Hemolysin III
FE36_00395	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
FE36_00405	COG4772	TonB-dependent receptor
FE36_00500	COG3237	CsbD-like
FE36_00550	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FE36_00560	COG0477	Major facilitator Superfamily
FE36_00585	COG0302	gtp cyclohydrolase
FE36_00635	COG0676	glucose-6-phosphate 1-epimerase activity
FE36_00655	COG3135	benzoate transporter
FE36_00685	COG0366	Alpha amylase catalytic
FE36_00690	COG0366	Alpha amylase catalytic
FE36_00715	COG1609	Transcriptional regulator
FE36_00735	COG3186	Phenylalanine-4-hydroxylase
FE36_00740	COG1522	sequence-specific DNA binding
FE36_00750	COG1752	Esterase of the alpha-beta hydrolase superfamily
FE36_00755	COG1473	amidohydrolase
FE36_00765	COG1119	ATPase activity
FE36_00780	COG1125	glycine betaine transport
FE36_00780	COG0517	IMP dehydrogenase activity
FE36_00795	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FE36_00800	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
FE36_00805	COG3550	peptidyl-serine autophosphorylation
FE36_00810	COG1396	sequence-specific DNA binding
FE36_00835	COG0489	protein tyrosine kinase activity
FE36_00840	COG2062	phosphohistidine phosphatase, SixA
FE36_00850	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FE36_00900	COG0174	glutamine synthetase
FE36_00905	COG0347	Belongs to the P(II) protein family
FE36_00910	COG0004	ammonium transporteR
FE36_00915	COG3852	Histidine kinase
FE36_00920	COG2204	response regulator
FE36_00925	COG2032	superoxide dismutase activity
FE36_00930	COG2032	superoxide dismutase activity
FE36_00955	COG0183	Belongs to the thiolase family
FE36_00995	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FE36_01000	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FE36_01015	COG0028	Belongs to the TPP enzyme family
FE36_01020	COG4191	Histidine kinase
FE36_01045	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FE36_01060	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FE36_01065	COG3177	Filamentation induced by cAMP protein fic
FE36_01070	COG0596	Alpha beta hydrolase
FE36_01080	COG0318	PFAM AMP-dependent synthetase and ligase
FE36_01085	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FE36_01100	COG1181	Belongs to the D-alanine--D-alanine ligase family
FE36_01130	COG0564	pseudouridine synthase activity
FE36_01155	COG0339	signal peptide processing
FE36_01170	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FE36_01175	COG3265	gluconokinase activity
FE36_01185	COG3459	Glycosyltransferase 36 associated
FE36_01200	COG2205	protein histidine kinase activity
FE36_01210	COG1414	Transcriptional regulator
FE36_01245	COG3162	membrane
FE36_01250	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FE36_01265	COG0708	Exodeoxyribonuclease III
FE36_01285	COG2091	lysine biosynthetic process via aminoadipic acid
FE36_01295	COG3540	Alkaline phosphatase
FE36_01300	COG0357	Ribosomal RNA small subunit methyltransferase G
FE36_01315	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FE36_01320	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FE36_01325	COG2159	amidohydrolase
FE36_01340	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FE36_01345	COG0583	DNA-binding transcription factor activity
FE36_01350	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FE36_01370	COG0210	DNA helicase
FE36_01440	COG1028	Short-chain dehydrogenase reductase Sdr
FE36_01475	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FE36_01490	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FE36_01550	COG0463	Glycosyl transferase, family 2
FE36_01560	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FE36_01565	COG3100	YcgL domain-containing protein
FE36_01580	COG3387	PFAM Glycoside hydrolase 15-related
FE36_01585	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FE36_01610	COG2239	Acts as a magnesium transporter
FE36_01620	COG0045	succinate-CoA ligase (ADP-forming) activity
FE36_01620	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FE36_01620	COG1042	CoA-binding domain protein
FE36_01630	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FE36_01635	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FE36_01675	COG0513	Belongs to the DEAD box helicase family
FE36_01685	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FE36_01715	COG1755	Isoprenylcysteine carboxyl methyltransferase
FE36_01725	COG3039	Transposase
FE36_01735	COG0508	dehydrogenase complex catalyzes the overall conversion of
FE36_01750	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FE36_01775	COG3104	oligopeptide transport
FE36_01820	COG1320	monovalent cation:proton antiporter activity
FE36_01825	COG2212	antiporter activity
FE36_01835	COG0651	ATP synthesis coupled electron transport
FE36_01840	COG1006	Multisubunit Na H antiporter MnhC subunit
FE36_01845	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FE36_01845	COG2111	Na H antiporter
FE36_01865	COG0708	Exodeoxyribonuclease III
FE36_01870	COG2211	Major facilitator Superfamily
FE36_01885	COG0739	heme binding
FE36_01905	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FE36_01920	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
FE36_01970	COG0358	DNA primase activity
FE36_01975	COG1295	ribonuclease BN
FE36_01985	COG1610	YqeY-like protein
FE36_01990	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FE36_02000	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FE36_02015	COG2133	pyrroloquinoline quinone binding
FE36_02025	COG4682	membrane
FE36_02040	COG0531	amino acid
FE36_02050	COG4948	Mandelate Racemase Muconate Lactonizing
FE36_02060	COG3023	N-Acetylmuramoyl-L-alanine amidase
FE36_02065	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
FE36_02105	COG5383	Protein conserved in bacteria
FE36_02130	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FE36_02135	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FE36_02140	COG1473	amidohydrolase
FE36_02185	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FE36_02190	COG3118	belongs to the thioredoxin family
FE36_02200	COG2884	Cell division ATP-binding protein ftsE
FE36_02205	COG2177	Part of the ABC transporter FtsEX involved in
FE36_02210	COG2201	protein-glutamate methylesterase activity
FE36_02220	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FE36_02225	COG2860	membrane
FE36_02230	COG1252	NADH dehydrogenase
FE36_02255	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FE36_02260	COG0459	protein refolding
FE36_02280	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FE36_02295	COG3386	PFAM SMP-30 Gluconolaconase
FE36_02305	COG4221	oxidoreductase activity
FE36_02345	COG0697	spore germination
FE36_02350	COG4305	rare lipoprotein A
FE36_02360	COG1113	amino acid transport
FE36_02375	COG0598	Magnesium transport protein CorA
FE36_02455	COG0659	secondary active sulfate transmembrane transporter activity
FE36_02480	COG3275	phosphorelay sensor kinase activity
FE36_02520	COG1505	serine-type exopeptidase activity
FE36_02540	COG2832	Protein of unknown function (DUF454)
FE36_02560	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FE36_02600	COG5001	Diguanylate cyclase
FE36_02600	COG3300	MHYT domain
FE36_02625	COG1077	Cell shape determining protein MreB Mrl
FE36_02630	COG1792	Involved in formation and maintenance of cell shape
FE36_02645	COG0772	Belongs to the SEDS family
FE36_02670	COG2951	lytic endotransglycosylase activity
FE36_02675	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FE36_02685	COG1686	Belongs to the peptidase S11 family
FE36_02720	COG1056	cytidyltransferase-related domain
FE36_02720	COG1051	belongs to the nudix hydrolase family
FE36_02760	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FE36_02765	COG0673	inositol 2-dehydrogenase activity
FE36_02770	COG2823	Periplasmic or secreted lipoprotein
FE36_02775	COG4251	negative regulation of phosphorylation
FE36_02780	COG0784	Response regulator, receiver
FE36_02785	COG4191	Histidine kinase
FE36_02790	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FE36_02830	COG3250	beta-galactosidase activity
FE36_02855	COG1609	Transcriptional regulator
FE36_02860	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FE36_02865	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FE36_02880	COG1215	transferase activity, transferring glycosyl groups
FE36_02885	COG0726	polysaccharide deacetylase
FE36_02885	COG1649	PFAM Uncharacterised BCR, COG1649
FE36_02905	COG1012	belongs to the aldehyde dehydrogenase family
FE36_02950	COG2205	protein histidine kinase activity
FE36_02980	COG0745	RESPONSE REGULATOR receiver
FE36_03025	COG0488	(ABC) transporter
FE36_03055	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FE36_03065	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FE36_03065	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FE36_03100	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FE36_03120	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FE36_03125	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FE36_03135	COG2205	protein histidine kinase activity
FE36_03140	COG0745	RESPONSE REGULATOR receiver
FE36_03145	COG0277	FAD linked oxidase domain protein
FE36_03150	COG1988	membrane-bound metal-dependent
FE36_03190	COG3116	cell division
FE36_03205	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FE36_03210	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FE36_03230	COG1181	Belongs to the D-alanine--D-alanine ligase family
FE36_03235	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FE36_03260	COG1388	LysM domain
FE36_03260	COG4942	peptidase
FE36_03275	COG0494	nUDIX hydrolase
FE36_03285	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FE36_03295	COG3321	synthase
FE36_03295	COG1028	Short-chain dehydrogenase reductase Sdr
FE36_03295	COG0604	alcohol dehydrogenase
FE36_03345	COG2226	methyltransferase
FE36_03390	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FE36_03405	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FE36_03420	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FE36_03425	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FE36_03435	COG0667	Aldo Keto reductase
FE36_03475	COG2175	clavaminate synthase activity
FE36_03485	COG4181	ATPase activity
FE36_03500	COG0642	Histidine kinase
FE36_03510	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FE36_03550	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FE36_03565	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FE36_03580	COG0123	including yeast histone deacetylase and acetoin utilization protein
FE36_03585	COG2096	Adenosyltransferase
FE36_03595	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FE36_03600	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FE36_03630	COG3384	dioxygenase
FE36_03635	COG0583	DNA-binding transcription factor activity
FE36_03640	COG0318	PFAM AMP-dependent synthetase and ligase
FE36_03650	COG1024	Enoyl-CoA hydratase
FE36_03670	COG3386	PFAM SMP-30 Gluconolaconase
FE36_03695	COG0697	spore germination
FE36_03720	COG3706	GGDEF domain
FE36_03720	COG0745	RESPONSE REGULATOR receiver
FE36_03725	COG2197	response regulator
FE36_03735	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FE36_03740	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FE36_03750	COG0583	DNA-binding transcription factor activity
FE36_03755	COG3634	alkyl hydroperoxide reductase activity
FE36_03765	COG2890	protein-(glutamine-N5) methyltransferase activity
FE36_03815	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
FE36_03840	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
FE36_03845	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FE36_03865	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FE36_03875	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FE36_03905	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FE36_03925	COG0521	Mo-molybdopterin cofactor biosynthetic process
FE36_03945	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FE36_03970	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FE36_03985	COG0012	GTP binding
FE36_04015	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FE36_04020	COG0250	Participates in transcription elongation, termination and antitermination
FE36_04030	COG0081	regulation of translation
FE36_04035	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FE36_04055	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FE36_04090	COG0089	rRNA binding
FE36_04095	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FE36_04115	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FE36_04120	COG0255	Belongs to the universal ribosomal protein uL29 family
FE36_04125	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FE36_04135	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FE36_04145	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FE36_04165	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FE36_04170	COG1841	ribosomal large subunit assembly
FE36_04175	COG0200	Binds to the 23S rRNA
FE36_04180	COG0201	protein transport
FE36_04185	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FE36_04200	COG0202	RNA polymerase activity
FE36_04205	COG0203	ribosomal protein L17
FE36_04210	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FE36_04225	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
FE36_04235	COG0154	amidase activity
FE36_04255	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FE36_04315	COG1902	pentaerythritol trinitrate reductase activity
FE36_04315	COG0446	pyridine nucleotide-disulphide oxidoreductase
FE36_04320	COG0604	alcohol dehydrogenase
FE36_04345	COG0156	8-amino-7-oxononanoate synthase activity
FE36_04350	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FE36_04355	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FE36_04360	COG4208	sulfate ABC transporter
FE36_04365	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FE36_04375	COG1063	alcohol dehydrogenase
FE36_04395	COG0406	alpha-ribazole phosphatase activity
FE36_04400	COG0285	dihydrofolate synthase activity
FE36_04420	COG2833	Protein of unknown function (DUF455)
FE36_04425	COG3291	Pkd domain containing protein
FE36_04445	COG0671	phosphoesterase, PA-phosphatase related
FE36_04450	COG0438	transferase activity, transferring glycosyl groups
FE36_04460	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FE36_04475	COG4783	chaperone-mediated protein folding
FE36_04490	COG0473	3-isopropylmalate dehydrogenase activity
FE36_04535	COG0544	peptidyl-prolyl cis-trans isomerase activity
FE36_04540	COG0740	serine-type endopeptidase activity
FE36_04570	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FE36_04595	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FE36_04600	COG0631	protein serine/threonine phosphatase activity
FE36_04615	COG0859	PFAM glycosyl transferase family 9
FE36_04625	COG1234	tRNA 3'-trailer cleavage
FE36_04630	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FE36_04645	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
FE36_04650	COG0314	molybdopterin synthase activity
FE36_04665	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FE36_04675	COG0537	adenosine 5'-monophosphoramidase activity
FE36_04695	COG0714	Associated with various cellular activities
FE36_04715	COG1399	metal-binding, possibly nucleic acid-binding protein
FE36_04740	COG1028	Short-chain dehydrogenase reductase Sdr
FE36_04755	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FE36_04760	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FE36_04790	COG3829	transcription factor binding
FE36_04805	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FE36_04865	COG0678	peroxiredoxin activity
FE36_04885	COG0330	HflC and HflK could
FE36_04890	COG0330	HflC and HflK could
FE36_04905	COG0308	aminopeptidase N
FE36_04950	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
FE36_04985	COG0732	type I restriction modification DNA specificity domain
FE36_05025	COG0328	RNA-DNA hybrid ribonuclease activity
FE36_05025	COG0406	alpha-ribazole phosphatase activity
FE36_05065	COG0587	DNA-directed DNA polymerase activity
FE36_05080	COG1297	OPT oligopeptide transporter protein
FE36_05095	COG0823	Involved in the tonB-independent uptake of proteins
FE36_05095	COG1506	peptidase
FE36_05105	COG1917	Cupin 2, conserved barrel domain protein
FE36_05105	COG2207	Transcriptional regulator
FE36_05125	COG0753	catalase activity
FE36_05165	COG3551	Protein conserved in bacteria
FE36_05200	COG2194	sulfuric ester hydrolase activity
FE36_05210	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FE36_05215	COG0745	RESPONSE REGULATOR receiver
FE36_05220	COG0642	Histidine kinase
FE36_05230	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FE36_05235	COG2894	cell division
FE36_05250	COG4585	Histidine kinase
FE36_05255	COG2197	response regulator
FE36_05270	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FE36_05295	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
FE36_05300	COG2963	transposase activity
FE36_05355	COG3501	Rhs element vgr protein
FE36_05525	COG1842	Phage shock protein A
FE36_05550	COG0754	glutathionylspermidine amidase activity
FE36_05585	COG0789	Transcriptional regulator
FE36_05645	COG0531	amino acid
FE36_05650	COG2197	response regulator
FE36_05660	COG1113	amino acid transport
FE36_05665	COG1271	oxidase subunit
FE36_05670	COG1294	oxidase, subunit
FE36_05680	COG2239	Acts as a magnesium transporter
FE36_05685	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FE36_05690	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FE36_05710	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FE36_05725	COG1137	ATPase activity
FE36_05730	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FE36_05740	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FE36_05750	COG0271	Belongs to the BolA IbaG family
FE36_05755	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FE36_05775	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FE36_05800	COG0628	permease
FE36_05810	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FE36_05815	COG3178	'Phosphotransferase
FE36_05825	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FE36_05830	COG1555	photosystem II stabilization
FE36_05840	COG3039	Transposase
FE36_05855	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FE36_05860	COG0719	Fe-S assembly protein
FE36_05865	COG0396	ATPase activity
FE36_05870	COG0719	Fe-S assembly protein
FE36_05875	COG1959	2 iron, 2 sulfur cluster binding
FE36_05920	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FE36_05945	COG0519	Catalyzes the synthesis of GMP from XMP
FE36_05960	COG1678	Uncharacterized ACR, COG1678
FE36_05970	COG0540	Belongs to the ATCase OTCase family
FE36_05980	COG1764	response to oxidative stress
FE36_05990	COG0384	phenazine biosynthesis protein PhzF
FE36_06000	COG0527	aspartate kinase activity
FE36_06030	COG0142	geranyltranstransferase activity
FE36_06035	COG0629	single-stranded DNA binding
FE36_06040	COG5001	Diguanylate cyclase
FE36_06040	COG2203	Gaf domain
FE36_06040	COG3706	GGDEF domain
FE36_06040	COG4251	negative regulation of phosphorylation
FE36_06045	COG3321	synthase
FE36_06045	COG1028	Short-chain dehydrogenase reductase Sdr
FE36_06045	COG0604	alcohol dehydrogenase
FE36_06055	COG2080	2 iron, 2 sulfur cluster binding
FE36_06060	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
FE36_06065	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FE36_06105	COG2879	small protein
FE36_06110	COG1966	Carbon starvation protein
FE36_06115	COG1741	Belongs to the pirin family
FE36_06145	COG1741	Belongs to the pirin family
FE36_06150	COG1515	deoxyribonuclease V activity
FE36_06170	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FE36_06175	COG2202	Pas domain
FE36_06175	COG2200	EAL domain
FE36_06175	COG2199	diguanylate cyclase activity
FE36_06180	COG0835	chemotaxis
FE36_06185	COG0840	transmembrane signaling receptor activity
FE36_06190	COG2198	Histidine kinase
FE36_06190	COG0643	Histidine kinase
FE36_06200	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FE36_06210	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FE36_06255	COG0735	belongs to the Fur family
FE36_06320	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FE36_06365	COG5001	Diguanylate cyclase
FE36_06365	COG5002	protein histidine kinase activity
FE36_06370	COG1187	pseudouridine synthase activity
FE36_06390	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FE36_06395	COG0475	glutathione-regulated potassium exporter activity
FE36_06400	COG5002	protein histidine kinase activity
FE36_06400	COG5000	phosphorelay sensor kinase activity
FE36_06405	COG0745	RESPONSE REGULATOR receiver
FE36_06435	COG1132	(ABC) transporter
FE36_06500	COG3118	belongs to the thioredoxin family
FE36_06525	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FE36_06565	COG2968	Membrane
FE36_06575	COG1530	ribonuclease E activity
FE36_06580	COG3164	Protein of unknown function
FE36_06590	COG0312	modulator of DNA gyrase
FE36_06595	COG3028	Belongs to the UPF0307 family
FE36_06600	COG0312	modulator of DNA gyrase
FE36_06620	COG4104	PAAR repeat-containing protein
FE36_06625	COG0142	geranyltranstransferase activity
FE36_06630	COG1722	exodeoxyribonuclease VII activity
FE36_06635	COG0037	tRNA processing
FE36_06640	COG1785	Belongs to the alkaline phosphatase family
FE36_06645	COG1301	dicarboxylic acid transport
FE36_06650	COG4106	trans-aconitate 2-methyltransferase activity
FE36_06665	COG0791	NLP P60 protein
FE36_06670	COG0791	NLP P60 protein
FE36_06675	COG1047	Peptidyl-prolyl cis-trans
FE36_06680	COG2311	Membrane
FE36_06685	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FE36_06715	COG3590	peptidase
FE36_06730	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FE36_06740	COG2914	Belongs to the UPF0125 (RnfH) family
FE36_06745	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FE36_06755	COG0497	DNA recombination
FE36_06770	COG0443	Heat shock 70 kDa protein
FE36_06780	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
FE36_06790	COG0583	DNA-binding transcription factor activity
FE36_06795	COG1132	(ABC) transporter
FE36_06890	COG1131	(ABC) transporter
FE36_06895	COG1725	Transcriptional regulator
FE36_06900	COG0386	Belongs to the glutathione peroxidase family
FE36_06940	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FE36_06965	COG1960	acyl-CoA dehydrogenase activity
FE36_06985	COG0557	exoribonuclease II activity
FE36_06995	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FE36_07010	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FE36_07020	COG0704	Plays a role in the regulation of phosphate uptake
FE36_07035	COG0573	inorganic phosphate transmembrane transporter activity
FE36_07040	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FE36_07070	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FE36_07080	COG1024	Enoyl-CoA hydratase
FE36_07090	COG0494	nUDIX hydrolase
FE36_07135	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FE36_07150	COG0667	Aldo Keto reductase
FE36_07160	COG2925	Exonuclease
FE36_07170	COG3844	kynureninase activity
FE36_07185	COG0288	reversible hydration of carbon dioxide
FE36_07215	COG0316	Belongs to the HesB IscA family
FE36_07240	COG3115	cell septum assembly
FE36_07265	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
FE36_07285	COG2801	Transposase and inactivated derivatives
FE36_07290	COG2963	transposase activity
FE36_07300	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FE36_07305	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FE36_07310	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FE36_07315	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FE36_07325	COG0776	regulation of translation
FE36_07375	COG0438	transferase activity, transferring glycosyl groups
FE36_07380	COG0438	transferase activity, transferring glycosyl groups
FE36_07430	COG1960	acyl-CoA dehydrogenase activity
FE36_07440	COG3040	lipid binding
FE36_07470	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FE36_07475	COG0784	Response regulator, receiver
FE36_07475	COG4191	Histidine kinase
FE36_07485	COG1194	a g-specific adenine glycosylase
FE36_07495	COG0552	protein localization to endoplasmic reticulum
FE36_07505	COG3938	Belongs to the proline racemase family
FE36_07510	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FE36_07525	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FE36_07535	COG0006	proline dipeptidase activity
FE36_07550	COG0531	amino acid
FE36_07605	COG4206	TonB-dependent receptor
FE36_07645	COG0326	Molecular chaperone. Has ATPase activity
FE36_07650	COG0742	ribosomal rna small subunit methyltransferase
FE36_07670	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FE36_07675	COG0405	Gamma-glutamyltransferase
FE36_07745	COG1862	Preprotein translocase
FE36_07755	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FE36_07770	COG2963	transposase activity
FE36_07800	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FE36_07800	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FE36_07805	COG1105	Belongs to the carbohydrate kinase PfkB family
FE36_07810	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FE36_07810	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FE36_07815	COG1609	Transcriptional regulator
FE36_07825	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FE36_07830	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FE36_07840	COG2902	Dehydrogenase
FE36_07850	COG0477	Major facilitator Superfamily
FE36_07860	COG0784	Response regulator, receiver
FE36_07860	COG2205	protein histidine kinase activity
FE36_07860	COG5002	protein histidine kinase activity
FE36_07865	COG2733	membrane
FE36_07875	COG1121	(ABC) transporter
FE36_07900	COG0243	molybdopterin cofactor binding
FE36_07910	COG0477	Major facilitator Superfamily
FE36_07920	COG3706	GGDEF domain
FE36_07920	COG0745	RESPONSE REGULATOR receiver
FE36_07925	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FE36_07930	COG0174	glutamine synthetase
FE36_07935	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FE36_07950	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FE36_07970	COG3842	ATPase activity
FE36_07975	COG1176	ABC-type spermidine putrescine transport system, permease component I
FE36_07980	COG1177	transmembrane transport
FE36_07985	COG1012	belongs to the aldehyde dehydrogenase family
FE36_08000	COG4535	Mg2 and Co2 transporter CorC
FE36_08020	COG1702	phosphate starvation-inducible protein PhoH
FE36_08040	COG0741	lytic transglycosylase activity
FE36_08050	COG0723	plastoquinol--plastocyanin reductase activity
FE36_08055	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FE36_08060	COG2857	Cytochrome c1
FE36_08065	COG0625	glutathione transferase activity
FE36_08070	COG2969	positive regulation of protein catabolic process
FE36_08085	COG1201	RNA secondary structure unwinding
FE36_08105	COG0840	transmembrane signaling receptor activity
FE36_08110	COG0835	chemotaxis
FE36_08125	COG2801	Transposase and inactivated derivatives
FE36_08225	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FE36_08300	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FE36_08315	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FE36_08320	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FE36_08320	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FE36_08325	COG0802	atpase or kinase
FE36_08330	COG0860	N-Acetylmuramoyl-L-alanine amidase
FE36_08355	COG1028	Short-chain dehydrogenase reductase Sdr
FE36_08375	COG2081	HI0933 family
FE36_08380	COG4681	YaeQ
FE36_08395	COG0625	glutathione transferase activity
FE36_08405	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FE36_08415	COG0513	Belongs to the DEAD box helicase family
FE36_08445	COG0483	inositol monophosphate 1-phosphatase activity
FE36_08460	COG3300	MHYT domain
FE36_08460	COG5001	Diguanylate cyclase
FE36_08465	COG1509	lysine 2,3-aminomutase activity
FE36_08480	COG0402	S-adenosylhomocysteine deaminase activity
FE36_08525	COG1741	Belongs to the pirin family
FE36_08530	COG0583	DNA-binding transcription factor activity
FE36_08565	COG0352	thiamine-phosphate diphosphorylase activity
FE36_08565	COG0351	phosphomethylpyrimidine kinase
FE36_08575	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FE36_08580	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FE36_08595	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FE36_08605	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FE36_08610	COG3734	2-keto-3-deoxy-galactonokinase
FE36_08625	COG0800	Aldolase
FE36_08650	COG1070	Carbohydrate kinase
FE36_08665	COG0477	Major facilitator Superfamily
FE36_08670	COG0860	N-Acetylmuramoyl-L-alanine amidase
FE36_08690	COG0617	tRNA 3'-terminal CCA addition
FE36_08710	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
FE36_08740	COG1472	Belongs to the glycosyl hydrolase 3 family
FE36_08750	COG5001	Diguanylate cyclase
FE36_08750	COG4251	negative regulation of phosphorylation
FE36_08750	COG3706	GGDEF domain
FE36_08750	COG2203	Gaf domain
FE36_08755	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
FE36_08760	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
FE36_08775	COG0671	phosphoesterase, PA-phosphatase related
FE36_08790	COG0697	spore germination
FE36_08795	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FE36_08815	COG1012	belongs to the aldehyde dehydrogenase family
FE36_08875	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FE36_08890	COG0124	histidyl-tRNA synthetase
FE36_08935	COG0140	phosphoribosyl-ATP diphosphatase activity
FE36_08935	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FE36_08960	COG0235	Class ii aldolase
FE36_08965	COG0531	amino acid
FE36_08980	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FE36_08990	COG0277	FAD linked oxidase domain protein
FE36_09010	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FE36_09060	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FE36_09065	COG2258	MOSC domain
FE36_09070	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FE36_09075	COG0505	Belongs to the CarA family
FE36_09085	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FE36_09090	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FE36_09100	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FE36_09110	COG3279	Response regulator of the LytR AlgR family
FE36_09115	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FE36_09130	COG2205	protein histidine kinase activity
FE36_09130	COG0784	Response regulator, receiver
FE36_09130	COG2198	Histidine kinase
FE36_09135	COG1024	Enoyl-CoA hydratase
FE36_09140	COG0318	PFAM AMP-dependent synthetase and ligase
FE36_09170	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FE36_09205	COG0835	chemotaxis
FE36_09215	COG0840	transmembrane signaling receptor activity
FE36_09235	COG0840	transmembrane signaling receptor activity
FE36_09245	COG0840	transmembrane signaling receptor activity
FE36_09255	COG0840	transmembrane signaling receptor activity
FE36_09275	COG0840	transmembrane signaling receptor activity
FE36_09300	COG0745	RESPONSE REGULATOR receiver
FE36_09310	COG0835	chemotaxis
FE36_09315	COG1192	Involved in chromosome partitioning
FE36_09320	COG1360	Flagellar Motor Protein
FE36_09325	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FE36_09340	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FE36_09375	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FE36_09410	COG0643	Histidine kinase
FE36_09410	COG2198	Histidine kinase
FE36_09430	COG0455	bacterial-type flagellum organization
FE36_09455	COG5001	Diguanylate cyclase
FE36_09455	COG3300	MHYT domain
FE36_09460	COG5001	Diguanylate cyclase
FE36_09460	COG3300	MHYT domain
FE36_09465	COG1684	flagellar biosynthetic protein fliR
FE36_09470	COG1987	bacterial-type flagellum assembly
FE36_09490	COG3190	flagellar
FE36_09540	COG1677	Flagellar hook-basal body complex protein FliE
FE36_09565	COG1028	Short-chain dehydrogenase reductase Sdr
FE36_09570	COG4221	oxidoreductase activity
FE36_09575	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FE36_09590	COG2204	response regulator
FE36_09595	COG2201	protein-glutamate methylesterase activity
FE36_09625	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FE36_09630	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FE36_09645	COG1705	Flagellar rod assembly protein muramidase FlgJ
FE36_09645	COG3951	Flagellar rod assembly protein muramidase FlgJ
FE36_09660	COG4786	Flagellar basal body rod
FE36_09665	COG4787	bacterial-type flagellum-dependent cell motility
FE36_09670	COG1749	Flagellar hook protein flgE
FE36_09675	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FE36_09680	COG1558	bacterial-type flagellum-dependent cell motility
FE36_09690	COG0784	Response regulator, receiver
FE36_09690	COG0835	chemotaxis
FE36_09710	COG4191	Histidine kinase
FE36_09720	COG4585	Histidine kinase
FE36_09755	COG0482	sulfurtransferase activity
FE36_09770	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FE36_09775	COG0542	response to heat
FE36_09780	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FE36_09800	COG0492	ferredoxin-NADP+ reductase activity
FE36_09805	COG1674	ftsk spoiiie
FE36_09825	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FE36_09845	COG0038	chloride channel
FE36_09850	COG0183	Belongs to the thiolase family
FE36_09855	COG1024	Enoyl-CoA hydratase
FE36_09855	COG1250	3-hydroxyacyl-CoA dehydrogenase
FE36_09865	COG0105	UTP biosynthetic process
FE36_09890	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FE36_09895	COG1160	GTP binding
FE36_09900	COG0303	'Molybdopterin
FE36_09905	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FE36_09940	COG0746	molybdenum cofactor guanylyltransferase activity
FE36_09965	COG1648	precorrin-2 dehydrogenase activity
FE36_09965	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FE36_10005	COG5001	Diguanylate cyclase
FE36_10020	COG4566	intracellular signal transduction
FE36_10100	COG3328	transposase activity
FE36_10110	COG3039	Transposase
FE36_10175	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FE36_10180	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FE36_10215	COG2963	transposase activity
FE36_10245	COG1858	cytochrome C peroxidase
FE36_10270	COG0515	serine threonine protein kinase
FE36_10275	COG0631	protein serine/threonine phosphatase activity
FE36_10310	COG3501	Rhs element vgr protein
FE36_10320	COG3039	Transposase
FE36_10410	COG2154	pterin-4-alpha-carbinolamine dehydratase
FE36_10425	COG0428	transporter
FE36_10430	COG3064	Membrane
FE36_10440	COG1530	ribonuclease E activity
FE36_10470	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FE36_10485	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FE36_10485	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
FE36_10535	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FE36_10560	COG0811	peptide transport
FE36_10585	COG4591	ABC-type transport system involved in lipoprotein release permease component
FE36_10600	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FE36_10615	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
FE36_10625	COG0354	folic acid binding
FE36_10635	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FE36_10645	COG0363	glucosamine-6-phosphate deaminase activity
FE36_10650	COG0129	dihydroxy-acid dehydratase activity
FE36_10655	COG0800	Aldolase
FE36_10760	COG2205	protein histidine kinase activity
FE36_10760	COG0784	Response regulator, receiver
FE36_10765	COG2183	response to ionizing radiation
FE36_10775	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FE36_10775	COG0723	plastoquinol--plastocyanin reductase activity
FE36_10790	COG3243	poly(R)-hydroxyalkanoic acid synthase
FE36_10800	COG1183	phosphatidylcholine synthase activity
FE36_10805	COG1028	Short-chain dehydrogenase reductase Sdr
FE36_10830	COG0668	transmembrane transport
FE36_10840	COG0590	tRNA wobble adenosine to inosine editing
FE36_10845	COG1321	iron dependent repressor
FE36_10850	COG1914	H( )-stimulated, divalent metal cation uptake system
FE36_10875	COG0583	DNA-binding transcription factor activity
FE36_10880	COG0583	DNA-binding transcription factor activity
FE36_10900	COG0583	DNA-binding transcription factor activity
FE36_10905	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FE36_10915	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FE36_10915	COG0519	Catalyzes the synthesis of GMP from XMP
FE36_10945	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FE36_10945	COG0475	glutathione-regulated potassium exporter activity
FE36_10960	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FE36_10970	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FE36_10975	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
FE36_10990	COG0539	negative regulation of cytoplasmic translation
FE36_10995	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FE36_11000	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FE36_11015	COG2957	Belongs to the agmatine deiminase family
FE36_11020	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FE36_11040	COG0395	ABC-type sugar transport system, permease component
FE36_11045	COG1175	transmembrane transport
FE36_11075	COG2350	Protein conserved in bacteria
FE36_11080	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FE36_11085	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FE36_11090	COG1187	pseudouridine synthase activity
FE36_11115	COG0436	Aminotransferase
FE36_11120	COG4133	protoheme IX ABC transporter activity
FE36_11175	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FE36_11180	COG4988	ABC transporter
FE36_11190	COG1271	oxidase subunit
FE36_11195	COG1294	oxidase, subunit
FE36_11255	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FE36_11260	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FE36_11270	COG0137	argininosuccinate synthase activity
FE36_11275	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FE36_11290	COG2166	iron-sulfur cluster assembly
FE36_11305	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FE36_11320	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FE36_11345	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FE36_11355	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
FE36_11365	COG2137	regulation of response to DNA damage stimulus
FE36_11390	COG1546	Belongs to the CinA family
FE36_11395	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FE36_11400	COG1923	regulation of RNA biosynthetic process
FE36_11410	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FE36_11415	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FE36_11425	COG1534	Rna-binding protein
FE36_11440	COG1238	metal cluster binding
FE36_11480	COG0148	phosphopyruvate hydratase activity
FE36_11530	COG1253	flavin adenine dinucleotide binding
FE36_11545	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FE36_11550	COG2271	Major facilitator Superfamily
FE36_11555	COG1132	(ABC) transporter
FE36_11575	COG0438	transferase activity, transferring glycosyl groups
FE36_11585	COG2264	protein methyltransferase activity
FE36_11615	COG2244	polysaccharide biosynthetic process
FE36_11665	COG1595	DNA-templated transcription, initiation
FE36_11680	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FE36_11700	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FE36_11715	COG0784	Response regulator, receiver
FE36_11715	COG4191	Histidine kinase
FE36_11720	COG4191	Histidine kinase
FE36_11720	COG0784	Response regulator, receiver
FE36_11730	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
FE36_11735	COG5002	protein histidine kinase activity
FE36_11735	COG2205	protein histidine kinase activity
FE36_11735	COG0784	Response regulator, receiver
FE36_11765	COG0840	transmembrane signaling receptor activity
FE36_11800	COG0583	DNA-binding transcription factor activity
FE36_11805	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FE36_11810	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FE36_11835	COG1605	Chorismate mutase
FE36_11835	COG0077	Prephenate dehydratase
FE36_11840	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FE36_11845	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FE36_11890	COG2986	histidine ammonia-lyase
FE36_11900	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FE36_11920	COG0556	nucleotide-excision repair
FE36_11925	COG4969	Belongs to the N-Me-Phe pilin family
FE36_11930	COG4974	Belongs to the 'phage' integrase family
FE36_12015	COG4695	Portal protein
FE36_12060	COG3179	chitinase
FE36_12270	COG1611	Belongs to the LOG family
FE36_12280	COG2095	MarC family integral membrane protein
FE36_12290	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FE36_12295	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FE36_12330	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FE36_12345	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FE36_12350	COG0195	Participates in both transcription termination and antitermination
FE36_12365	COG1007	ATP synthesis coupled electron transport
FE36_12380	COG0713	ATP synthesis coupled electron transport
FE36_12395	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FE36_12400	COG1034	ATP synthesis coupled electron transport
FE36_12405	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FE36_12410	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
FE36_12430	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FE36_12450	COG1028	Short-chain dehydrogenase reductase Sdr
FE36_12510	COG0133	tryptophan synthase activity
FE36_12540	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FE36_12545	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FE36_12555	COG2890	protein-(glutamine-N5) methyltransferase activity
FE36_12575	COG0433	COG0433 Predicted ATPase
FE36_12595	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FE36_12600	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FE36_12630	COG0489	protein tyrosine kinase activity
FE36_12645	COG3706	GGDEF domain
FE36_12655	COG3706	GGDEF domain
FE36_12665	COG1028	Short-chain dehydrogenase reductase Sdr
FE36_12680	COG0415	Belongs to the DNA photolyase family
FE36_12685	COG0305	Participates in initiation and elongation during chromosome replication
FE36_12695	COG0367	asparagine synthase
FE36_12715	COG1960	acyl-CoA dehydrogenase activity
FE36_12730	COG0084	hydrolase, TatD family'
FE36_12735	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FE36_12795	COG0386	Belongs to the glutathione peroxidase family
FE36_12825	COG1595	DNA-templated transcription, initiation
FE36_12895	COG2814	Major facilitator Superfamily
FE36_12900	COG1566	PFAM secretion protein HlyD family protein
FE36_12915	COG2207	Transcriptional regulator
FE36_12935	COG4774	siderophore transport
FE36_12945	COG0367	asparagine synthase
FE36_12950	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FE36_12960	COG1393	Belongs to the ArsC family
FE36_12980	COG0024	Methionine aminopeptidase
FE36_13030	COG3706	GGDEF domain
FE36_13030	COG0745	RESPONSE REGULATOR receiver
FE36_13050	COG0575	Belongs to the CDS family
FE36_13055	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FE36_13060	COG0750	zinc metalloprotease
FE36_13070	COG3039	Transposase
FE36_13075	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FE36_13105	COG0825	malonyl-CoA metabolic process
FE36_13140	COG1695	Transcriptional regulator
FE36_13160	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FE36_13170	COG2040	homocysteine
FE36_13175	COG0833	amino acid
FE36_13180	COG0346	lactoylglutathione lyase activity
FE36_13200	COG2878	Part of a membrane complex involved in electron transport
FE36_13220	COG1595	DNA-templated transcription, initiation
FE36_13245	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FE36_13260	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FE36_13265	COG0251	oxidation-reduction process
FE36_13280	COG0392	lysyltransferase activity
FE36_13280	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FE36_13310	COG2814	Major facilitator Superfamily
FE36_13315	COG1902	pentaerythritol trinitrate reductase activity
FE36_13330	COG2824	Alkylphosphonate utilization operon protein PhnA
FE36_13345	COG1047	Peptidyl-prolyl cis-trans
FE36_13380	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FE36_13400	COG1451	nucleotide metabolic process
FE36_13415	COG0183	Belongs to the thiolase family
FE36_13430	COG3706	GGDEF domain
FE36_13445	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FE36_13445	COG1793	dna ligase
FE36_13455	COG1793	dna ligase
FE36_13460	COG1201	RNA secondary structure unwinding
FE36_13475	COG1278	Cold shock
FE36_13480	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FE36_13495	COG3046	protein related to deoxyribodipyrimidine photolyase
FE36_13500	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
FE36_13505	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FE36_13545	COG0681	Belongs to the peptidase S26 family
FE36_13550	COG0481	GTPase activity
FE36_13555	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FE36_13570	COG1024	Enoyl-CoA hydratase
FE36_13570	COG1250	3-hydroxyacyl-CoA dehydrogenase
FE36_13595	COG1960	acyl-CoA dehydrogenase activity
FE36_13625	COG3867	Arabinogalactan endo-beta-1,4-galactanase
FE36_13660	COG5002	protein histidine kinase activity
FE36_13660	COG0784	Response regulator, receiver
FE36_13670	COG2353	YceI-like domain
FE36_13695	COG1760	l-serine dehydratase
FE36_13710	COG0626	cystathionine gamma-synthase activity
FE36_13715	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FE36_13720	COG0739	heme binding
FE36_13730	COG1272	protein, Hemolysin III
FE36_13740	COG0516	GMP reductase activity
FE36_13740	COG0517	IMP dehydrogenase activity
FE36_13745	COG0463	Glycosyl transferase, family 2
FE36_13755	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FE36_13765	COG4771	TonB-dependent receptor
FE36_13770	COG1309	transcriptional regulator
FE36_13780	COG1960	acyl-CoA dehydrogenase activity
FE36_13825	COG0330	HflC and HflK could
FE36_13830	COG1742	UPF0060 membrane protein
FE36_13835	COG3956	TIGRFAM MazG family protein
FE36_13845	COG0494	nUDIX hydrolase
FE36_13855	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FE36_13860	COG0837	glucose binding
FE36_13875	COG3858	chitin binding
FE36_13875	COG1388	LysM domain
FE36_13880	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FE36_13890	COG1472	Belongs to the glycosyl hydrolase 3 family
FE36_13910	COG3537	Alpha-1,2-mannosidase
FE36_13955	COG1446	asparaginase
FE36_13960	COG2304	oxidoreductase activity
FE36_13990	COG0840	transmembrane signaling receptor activity
FE36_13995	COG0835	chemotaxis
FE36_14010	COG0189	ligase activity
FE36_14030	COG1199	ATP-dependent helicase activity
FE36_14055	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FE36_14105	COG1643	Atp-dependent helicase
FE36_14110	COG0783	Belongs to the Dps family
FE36_14115	COG0514	ATP-dependent DNA helicase (RecQ)
FE36_14140	COG1187	pseudouridine synthase activity
FE36_14150	COG0840	transmembrane signaling receptor activity
FE36_14180	COG0602	queuosine metabolic process
FE36_14190	COG2885	chlorophyll binding
FE36_14195	COG0823	Involved in the tonB-independent uptake of proteins
FE36_14215	COG0824	Thioesterase
FE36_14265	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FE36_14285	COG0477	Major facilitator Superfamily
FE36_14300	COG0657	acetylesterase activity
FE36_14300	COG2755	lipolytic protein G-D-S-L family
FE36_14320	COG0488	(ABC) transporter
FE36_14355	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FE36_14355	COG4651	solute:proton antiporter activity
FE36_14365	COG4772	TonB-dependent receptor
FE36_14375	COG4264	IucA IucC family
FE36_14380	COG2814	Major facilitator Superfamily
FE36_14390	COG0019	diaminopimelate decarboxylase activity
FE36_14425	COG0542	response to heat
FE36_14450	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FE36_14460	COG0534	Mate efflux family protein
FE36_14490	COG2070	2-Nitropropane dioxygenase
FE36_14500	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FE36_14510	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FE36_14545	COG2172	sigma factor antagonist activity
FE36_14550	COG1366	Belongs to the anti-sigma-factor antagonist family
FE36_14555	COG1366	Belongs to the anti-sigma-factor antagonist family
FE36_14565	COG0326	Molecular chaperone. Has ATPase activity
FE36_14570	COG2207	Transcriptional regulator
FE36_14615	COG3501	Rhs element vgr protein
FE36_14625	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FE36_14630	COG1845	cytochrome c oxidase, subunit III
FE36_14635	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FE36_14655	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FE36_14670	COG0728	peptidoglycan biosynthetic process
FE36_14675	COG0268	Binds directly to 16S ribosomal RNA
FE36_14695	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FE36_14700	COG0824	Thioesterase
FE36_14715	COG1946	Acyl-CoA thioesterase
FE36_14725	COG1595	DNA-templated transcription, initiation
FE36_14785	COG1877	trehalose-phosphatase activity
FE36_14790	COG3387	PFAM Glycoside hydrolase 15-related
FE36_14810	COG0840	transmembrane signaling receptor activity
FE36_14815	COG3011	Protein conserved in bacteria
FE36_14830	COG0564	pseudouridine synthase activity
FE36_14835	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FE36_14840	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FE36_14840	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FE36_14850	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FE36_14890	COG2194	sulfuric ester hydrolase activity
FE36_14895	COG4969	Belongs to the N-Me-Phe pilin family
FE36_14905	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
FE36_14925	COG0745	RESPONSE REGULATOR receiver
FE36_14990	COG0471	metal ion transport
FE36_14990	COG3273	potassium ion transport
FE36_15010	COG1970	mechanosensitive ion channel activity
FE36_15020	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FE36_15040	COG0308	aminopeptidase N
FE36_15045	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FE36_15055	COG0529	Catalyzes the synthesis of activated sulfate
FE36_15055	COG2895	sulfate adenylyltransferase (ATP) activity
FE36_15065	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FE36_15095	COG2198	Histidine kinase
FE36_15095	COG0784	Response regulator, receiver
FE36_15095	COG2205	protein histidine kinase activity
FE36_15110	COG1648	precorrin-2 dehydrogenase activity
FE36_15110	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FE36_15135	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
FE36_15140	COG3588	fructose-bisphosphate aldolase
FE36_15145	COG0469	pyruvate kinase activity
FE36_15155	COG0126	phosphoglycerate kinase activity
FE36_15170	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FE36_15185	COG3453	Protein conserved in bacteria
FE36_15185	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FE36_15190	COG0725	ABC transporter, periplasmic molybdate-binding protein
FE36_15195	COG4149	molybdate abc transporter
FE36_15200	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FE36_15225	COG0745	RESPONSE REGULATOR receiver
FE36_15295	COG4773	Receptor
FE36_15305	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FE36_15310	COG1301	dicarboxylic acid transport
FE36_15325	COG2304	oxidoreductase activity
FE36_15345	COG0714	Associated with various cellular activities
FE36_15375	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FE36_15390	COG0254	rRNA binding
FE36_15400	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FE36_15410	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FE36_15415	COG1758	RNA polymerase activity
FE36_15425	COG1561	YicC-like family, N-terminal region
FE36_15435	COG0346	lactoylglutathione lyase activity
FE36_15445	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FE36_15470	COG0006	proline dipeptidase activity
FE36_15490	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FE36_15510	COG2912	Transglutaminase-like superfamily
FE36_15515	COG1773	rubredoxin
FE36_15520	COG0352	thiamine-phosphate diphosphorylase activity
FE36_15590	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FE36_15595	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FE36_15605	COG1028	Short-chain dehydrogenase reductase Sdr
FE36_15620	COG3781	membrane
FE36_15630	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FE36_15650	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
FE36_15660	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FE36_15680	COG3710	Transcriptional regulator
FE36_15725	COG2226	methyltransferase
FE36_15745	COG3706	GGDEF domain
FE36_15760	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FE36_15765	COG1538	Outer membrane efflux protein
FE36_15770	COG1519	Transferase
FE36_15775	COG1560	Kdo2-lipid A biosynthetic process
FE36_15805	COG0281	malic enzyme
FE36_15805	COG0280	phosphate acetyltransferase
FE36_15820	COG4191	Histidine kinase
FE36_15835	COG0583	DNA-binding transcription factor activity
FE36_15860	COG2197	response regulator
FE36_15865	COG1840	ABC-type Fe3 transport system, periplasmic component
FE36_15870	COG0642	Histidine kinase
FE36_15885	COG2851	Citrate transporter
FE36_15890	COG1028	Short-chain dehydrogenase reductase Sdr
FE36_15895	COG1609	Transcriptional regulator
FE36_15900	COG2211	Major facilitator Superfamily
FE36_15930	COG0436	Aminotransferase
FE36_15945	COG0726	polysaccharide deacetylase
FE36_15950	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FE36_15970	COG3964	amidohydrolase
FE36_15975	COG1228	amidohydrolase
FE36_15990	COG0242	peptide deformylase activity
FE36_16005	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FE36_16050	COG2188	Transcriptional regulator
FE36_16065	COG1450	Type ii and iii secretion system protein
FE36_16080	COG3166	PFAM Fimbrial assembly family protein
FE36_16085	COG3156	type II secretion system protein K
FE36_16090	COG4795	General secretion pathway protein
FE36_16095	COG2165	general secretion pathway protein
FE36_16100	COG4970	Tfp pilus assembly protein FimT
FE36_16105	COG2165	general secretion pathway protein
FE36_16110	COG1459	type II secretion system
FE36_16120	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FE36_16125	COG1404	Belongs to the peptidase S8 family
FE36_16130	COG5295	Hep Hag repeat protein
FE36_16135	COG0047	phosphoribosylformylglycinamidine synthase activity
FE36_16135	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FE36_16140	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FE36_16145	COG4974	Belongs to the 'phage' integrase family
FE36_16160	COG0795	lipopolysaccharide-transporting ATPase activity
FE36_16185	COG0525	valine-tRNA ligase activity
FE36_16210	COG1183	phosphatidylcholine synthase activity
FE36_16235	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FE36_16245	COG1127	ABC transporter
FE36_16250	COG3218	ABC-type transport auxiliary lipoprotein component
FE36_16250	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FE36_16285	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FE36_16290	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
FE36_16290	COG0662	Cupin 2, conserved barrel domain protein
FE36_16315	COG2086	electron transfer activity
FE36_16330	COG0546	phosphoglycolate phosphatase activity
FE36_16330	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FE36_16335	COG0277	FAD linked oxidase domain protein
FE36_16350	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FE36_16370	COG2226	methyltransferase
FE36_16380	COG3754	Rhamnan synthesis protein F
FE36_16385	COG0438	transferase activity, transferring glycosyl groups
FE36_16385	COG1216	Glycosyl transferase, family 2
FE36_16390	COG0110	maltose O-acetyltransferase activity
FE36_16405	COG0626	cystathionine gamma-synthase activity
FE36_16440	COG0625	glutathione transferase activity
FE36_16450	COG0513	Belongs to the DEAD box helicase family
FE36_16455	COG0720	synthase
FE36_16470	COG1956	GAF domain-containing protein
FE36_16480	COG0546	phosphoglycolate phosphatase activity
FE36_16505	COG0339	signal peptide processing
FE36_16545	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FE36_16550	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FE36_16555	COG1136	(ABC) transporter
FE36_16570	COG0577	efflux transmembrane transporter activity
FE36_16570	COG1136	(ABC) transporter
FE36_16575	COG1136	(ABC) transporter
FE36_16575	COG0577	efflux transmembrane transporter activity
FE36_16585	COG4191	Histidine kinase
FE36_16640	COG0356	it plays a direct role in the translocation of protons across the membrane
FE36_16660	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FE36_16670	COG0508	dehydrogenase complex catalyzes the overall conversion of
FE36_16710	COG2011	ABC-type metal ion transport system permease component
FE36_16720	COG0697	spore germination
FE36_16770	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FE36_16775	COG1187	pseudouridine synthase activity
FE36_16780	COG2813	Specifically methylates the guanine in position
FE36_16805	COG2205	protein histidine kinase activity
FE36_16805	COG2202	Pas domain
FE36_16830	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FE36_16835	COG1522	sequence-specific DNA binding
FE36_16880	COG0745	RESPONSE REGULATOR receiver
FE36_16895	COG1404	Belongs to the peptidase S8 family
FE36_16910	COG0842	Transport permease protein
FE36_16915	COG1131	(ABC) transporter
FE36_16925	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
FE36_16930	COG1573	uracil-dna glycosylase
FE36_16940	COG3384	dioxygenase
FE36_16955	COG0667	Aldo Keto reductase
FE36_16970	COG3590	peptidase
FE36_16985	COG0531	amino acid
FE36_17000	COG2972	Histidine kinase
FE36_17055	COG1271	oxidase subunit
FE36_17060	COG1294	oxidase, subunit
FE36_17075	COG1063	alcohol dehydrogenase
FE36_17155	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FE36_17190	COG2353	YceI-like domain
FE36_17230	COG2831	hemolysin activation secretion protein
FE36_17240	COG2951	lytic endotransglycosylase activity
FE36_17250	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FE36_17260	COG0842	Transport permease protein
FE36_17265	COG1131	(ABC) transporter
FE36_17270	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FE36_17295	COG1476	TRANSCRIPTIONal
FE36_17305	COG4555	ABC transporter
FE36_17345	COG0625	glutathione transferase activity
FE36_17370	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FE36_17380	COG1560	Kdo2-lipid A biosynthetic process
FE36_17430	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FE36_17430	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FE36_17440	COG0242	peptide deformylase activity
FE36_17445	COG1652	LysM domain
FE36_17450	COG0758	DNA mediated transformation
FE36_17470	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FE36_17470	COG1754	DNA topoisomerase type I activity
FE36_17490	COG1028	Short-chain dehydrogenase reductase Sdr
FE36_17500	COG0616	signal peptide processing
FE36_17505	COG0534	Mate efflux family protein
FE36_17525	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FE36_17530	COG1324	tolerance protein
FE36_17550	COG0511	ligase activity, forming carbon-carbon bonds
FE36_17555	COG0439	Biotin carboxylase
FE36_17590	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FE36_17625	COG0138	bifunctional purine biosynthesis protein purh
FE36_17630	COG0151	Belongs to the GarS family
FE36_17635	COG0577	efflux transmembrane transporter activity
FE36_17635	COG1136	(ABC) transporter
FE36_17645	COG1289	transmembrane transporter activity
FE36_17655	COG2814	Major facilitator Superfamily
FE36_17665	COG2814	Major facilitator Superfamily
FE36_17685	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
FE36_17760	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FE36_17780	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FE36_17790	COG0134	indole-3-glycerol-phosphate synthase activity
FE36_17835	COG0456	acetyltransferase
FE36_17845	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FE36_17870	COG1192	Involved in chromosome partitioning
FE36_17875	COG1475	DNA binding
FE36_17895	COG0463	Glycosyl transferase, family 2
FE36_17920	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FE36_17945	COG4221	oxidoreductase activity
FE36_17950	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FE36_17950	COG2755	lipolytic protein G-D-S-L family
FE36_17965	COG3039	Transposase
FE36_17970	COG1166	arginine decarboxylase activity
FE36_18020	COG0606	chelatase, subunit chli
FE36_18035	COG4943	cyclic-guanylate-specific phosphodiesterase activity
FE36_18085	COG1090	epimerase
FE36_18090	COG0642	Histidine kinase
FE36_18100	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FE36_18135	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FE36_18150	COG0753	catalase activity
FE36_18195	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FE36_18200	COG0180	Tryptophanyl-tRNA synthetase
FE36_18205	COG3237	CsbD-like
FE36_18255	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
FE36_18255	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
FE36_18265	COG3228	Belongs to the MtfA family
FE36_18280	COG2205	protein histidine kinase activity
FE36_18285	COG0745	RESPONSE REGULATOR receiver
FE36_18295	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FE36_18335	COG1199	ATP-dependent helicase activity
FE36_18370	COG0583	DNA-binding transcription factor activity
FE36_18405	COG0702	epimerase
FE36_18435	COG0583	DNA-binding transcription factor activity
FE36_18440	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FE36_18450	COG2205	protein histidine kinase activity
FE36_18455	COG2205	protein histidine kinase activity
FE36_18460	COG0745	RESPONSE REGULATOR receiver
FE36_18485	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FE36_18500	COG2814	Major facilitator Superfamily
FE36_18515	COG0084	hydrolase, TatD family'
FE36_18545	COG0702	epimerase
FE36_18570	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FE36_18585	COG3706	GGDEF domain
FE36_18585	COG0745	RESPONSE REGULATOR receiver
FE36_18595	COG2354	Protein conserved in bacteria
FE36_18600	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FE36_18615	COG1511	domain protein
FE36_18615	COG3264	Mechanosensitive ion channel
FE36_18690	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FE36_18790	COG0246	Mannitol dehydrogenase
FE36_18795	COG1472	Belongs to the glycosyl hydrolase 3 family
FE36_18805	COG4948	Mandelate Racemase Muconate Lactonizing
FE36_18815	COG3661	Belongs to the glycosyl hydrolase 67 family
FE36_18835	COG2974	May be involved in recombination
FE36_18855	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FE36_18865	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FE36_18870	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FE36_18875	COG0805	protein transport
FE36_18885	COG0519	Catalyzes the synthesis of GMP from XMP
FE36_18885	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FE36_18900	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FE36_18905	COG0752	glycyl-tRNA synthetase alpha subunit
FE36_18915	COG0457	Tetratricopeptide repeat
FE36_18925	COG4771	TonB-dependent receptor
FE36_18930	COG0729	surface antigen
FE36_18935	COG2911	Protein conserved in bacteria
FE36_18960	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FE36_18965	COG1040	competence protein
FE36_19020	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FE36_19060	COG1414	Transcriptional regulator
FE36_19070	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FE36_19075	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FE36_19085	COG3485	protocatechuate 3,4-dioxygenase
FE36_19090	COG3485	protocatechuate 3,4-dioxygenase
FE36_19100	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FE36_19105	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FE36_19130	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FE36_19180	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FE36_19200	COG2826	transposase and inactivated derivatives, IS30 family
FE36_19245	COG3693	PFAM glycoside hydrolase, family 10
FE36_19250	COG3693	PFAM glycoside hydrolase, family 10
FE36_19295	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FE36_19300	COG1960	acyl-CoA dehydrogenase activity
FE36_19355	COG0523	cobalamin synthesis protein
FE36_19380	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FE36_19385	COG1846	Transcriptional regulator
FE36_19390	COG1764	response to oxidative stress
FE36_19425	COG0656	L-ascorbic acid biosynthetic process
FE36_19430	COG2130	NADP-dependent
FE36_19435	COG0667	Aldo Keto reductase
FE36_19445	COG1187	pseudouridine synthase activity
FE36_19455	COG1643	Atp-dependent helicase
FE36_19465	COG4807	Protein conserved in bacteria
FE36_19475	COG2351	hydroxyisourate hydrolase activity
FE36_19495	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FE36_19530	COG2937	Belongs to the GPAT DAPAT family
FE36_19570	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
FE36_19600	COG0210	DNA helicase
FE36_19615	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
FE36_19630	COG0564	pseudouridine synthase activity
FE36_19650	COG3706	GGDEF domain
FE36_19660	COG1929	Belongs to the glycerate kinase type-1 family
FE36_19665	COG2271	Major facilitator Superfamily
FE36_19680	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FE36_19690	COG0584	glycerophosphoryl diester phosphodiesterase
FE36_19700	COG0671	phosphoesterase, PA-phosphatase related
FE36_19705	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FE36_19710	COG0726	polysaccharide deacetylase
FE36_19725	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FE36_19745	COG0187	DNA topoisomerase II activity
FE36_19755	COG0501	Belongs to the peptidase M48B family
FE36_19785	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FE36_19910	COG4962	Type ii secretion system protein e
FE36_19925	COG3451	type IV secretory pathway VirB4
FE36_20025	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FE36_20115	COG3504	Conjugal transfer protein
FE36_20120	COG2948	multi-organism process
FE36_20125	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
FE36_20215	COG2003	Belongs to the UPF0758 family
FE36_20225	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FE36_20245	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
FE36_20250	COG1518	maintenance of DNA repeat elements
FE36_20340	COG0489	protein tyrosine kinase activity
FE36_20375	COG0084	hydrolase, TatD family'
FE36_20460	COG3501	Rhs element vgr protein
FE36_20480	COG3328	transposase activity