locus-tag	class	description
IYN96_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IYN96_00020	COG0187	DNA topoisomerase II activity
IYN96_00030	COG0501	Belongs to the peptidase M48B family
IYN96_00060	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
IYN96_00070	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IYN96_00085	COG1064	alcohol dehydrogenase
IYN96_00090	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
IYN96_00100	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
IYN96_00115	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
IYN96_00125	COG2234	aminopeptidase activity
IYN96_00135	COG4942	peptidase
IYN96_00140	COG0793	Belongs to the peptidase S41A family
IYN96_00185	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
IYN96_00205	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
IYN96_00220	COG0210	DNA helicase
IYN96_00240	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
IYN96_00245	COG0284	orotidine-5'-phosphate decarboxylase activity
IYN96_00275	COG2937	Belongs to the GPAT DAPAT family
IYN96_00280	COG0604	alcohol dehydrogenase
IYN96_00280	COG1028	Short-chain dehydrogenase reductase Sdr
IYN96_00280	COG3321	synthase
IYN96_00320	COG2211	Major facilitator Superfamily
IYN96_00340	COG3693	PFAM glycoside hydrolase, family 10
IYN96_00375	COG4770	biotin carboxylase activity
IYN96_00380	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IYN96_00385	COG1960	acyl-CoA dehydrogenase activity
IYN96_00435	COG0523	cobalamin synthesis protein
IYN96_00460	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
IYN96_00465	COG1846	Transcriptional regulator
IYN96_00470	COG1764	response to oxidative stress
IYN96_00500	COG0656	L-ascorbic acid biosynthetic process
IYN96_00505	COG2130	NADP-dependent
IYN96_00510	COG0667	Aldo Keto reductase
IYN96_00520	COG1187	pseudouridine synthase activity
IYN96_00530	COG1643	Atp-dependent helicase
IYN96_00540	COG4807	Protein conserved in bacteria
IYN96_00545	COG2072	flavoprotein involved in K transport
IYN96_00565	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
IYN96_00590	COG0129	dihydroxy-acid dehydratase activity
IYN96_00600	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
IYN96_00670	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IYN96_00675	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IYN96_00685	COG3485	protocatechuate 3,4-dioxygenase
IYN96_00690	COG3485	protocatechuate 3,4-dioxygenase
IYN96_00705	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IYN96_00710	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IYN96_00725	COG1414	Transcriptional regulator
IYN96_00735	COG0657	acetylesterase activity
IYN96_00805	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IYN96_00845	COG0156	8-amino-7-oxononanoate synthase activity
IYN96_00850	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
IYN96_00855	COG1040	competence protein
IYN96_00860	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
IYN96_00885	COG2911	Protein conserved in bacteria
IYN96_00890	COG0729	surface antigen
IYN96_00895	COG4771	TonB-dependent receptor
IYN96_00905	COG0457	Tetratricopeptide repeat
IYN96_00915	COG0752	glycyl-tRNA synthetase alpha subunit
IYN96_00920	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IYN96_00930	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IYN96_00930	COG0519	Catalyzes the synthesis of GMP from XMP
IYN96_00940	COG0805	protein transport
IYN96_00945	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IYN96_00950	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IYN96_00960	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
IYN96_00985	COG2974	May be involved in recombination
IYN96_01005	COG3661	Belongs to the glycosyl hydrolase 67 family
IYN96_01015	COG4948	Mandelate Racemase Muconate Lactonizing
IYN96_01025	COG1472	Belongs to the glycosyl hydrolase 3 family
IYN96_01030	COG0246	Mannitol dehydrogenase
IYN96_01120	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
IYN96_01195	COG1511	domain protein
IYN96_01195	COG3264	Mechanosensitive ion channel
IYN96_01210	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
IYN96_01215	COG2354	Protein conserved in bacteria
IYN96_01220	COG1649	PFAM Uncharacterised BCR, COG1649
IYN96_01240	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
IYN96_01265	COG0702	epimerase
IYN96_01275	COG3039	Transposase
IYN96_01280	COG2826	transposase and inactivated derivatives, IS30 family
IYN96_01295	COG3039	Transposase
IYN96_01310	COG3039	Transposase
IYN96_01415	COG0084	hydrolase, TatD family'
IYN96_01435	COG2814	Major facilitator Superfamily
IYN96_01445	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
IYN96_01450	COG1902	pentaerythritol trinitrate reductase activity
IYN96_01480	COG0745	RESPONSE REGULATOR receiver
IYN96_01500	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IYN96_01505	COG0583	DNA-binding transcription factor activity
IYN96_01530	COG1733	regulation of RNA biosynthetic process
IYN96_01535	COG0702	epimerase
IYN96_01575	COG0583	DNA-binding transcription factor activity
IYN96_01615	COG1199	ATP-dependent helicase activity
IYN96_01625	COG1566	PFAM secretion protein HlyD family protein
IYN96_01645	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IYN96_01675	COG3228	Belongs to the MtfA family
IYN96_01685	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
IYN96_01685	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
IYN96_01690	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
IYN96_01705	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IYN96_01745	COG0180	Tryptophanyl-tRNA synthetase
IYN96_01750	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IYN96_01795	COG0753	catalase activity
IYN96_01810	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IYN96_01845	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IYN96_01855	COG0642	Histidine kinase
IYN96_01865	COG1090	epimerase
IYN96_01895	COG2826	transposase and inactivated derivatives, IS30 family
IYN96_01915	COG4943	cyclic-guanylate-specific phosphodiesterase activity
IYN96_01935	COG0606	chelatase, subunit chli
IYN96_02020	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
IYN96_02025	COG1166	arginine decarboxylase activity
IYN96_02045	COG2755	lipolytic protein G-D-S-L family
IYN96_02045	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
IYN96_02050	COG4221	oxidoreductase activity
IYN96_02075	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IYN96_02100	COG0463	Glycosyl transferase, family 2
IYN96_02115	COG1475	DNA binding
IYN96_02120	COG1192	Involved in chromosome partitioning
IYN96_02150	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
IYN96_02160	COG0456	acetyltransferase
IYN96_02195	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IYN96_02200	COG0134	indole-3-glycerol-phosphate synthase activity
IYN96_02210	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IYN96_02215	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
IYN96_02225	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
IYN96_02235	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
IYN96_02305	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
IYN96_02320	COG2814	Major facilitator Superfamily
IYN96_02335	COG1289	transmembrane transporter activity
IYN96_02345	COG0577	efflux transmembrane transporter activity
IYN96_02345	COG1136	(ABC) transporter
IYN96_02350	COG0151	Belongs to the GarS family
IYN96_02355	COG0138	bifunctional purine biosynthesis protein purh
IYN96_02385	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
IYN96_02425	COG0439	Biotin carboxylase
IYN96_02435	COG0511	ligase activity, forming carbon-carbon bonds
IYN96_02440	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
IYN96_02455	COG1324	tolerance protein
IYN96_02460	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IYN96_02480	COG0534	Mate efflux family protein
IYN96_02485	COG0616	signal peptide processing
IYN96_02495	COG1028	Short-chain dehydrogenase reductase Sdr
IYN96_02510	COG0009	L-threonylcarbamoyladenylate synthase
IYN96_02515	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IYN96_02515	COG1754	DNA topoisomerase type I activity
IYN96_02535	COG0758	DNA mediated transformation
IYN96_02540	COG1652	LysM domain
IYN96_02545	COG0242	peptide deformylase activity
IYN96_02550	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IYN96_02555	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IYN96_02555	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IYN96_02600	COG1560	Kdo2-lipid A biosynthetic process
IYN96_02610	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IYN96_02720	COG0625	glutathione transferase activity
IYN96_02755	COG4555	ABC transporter
IYN96_02765	COG1476	TRANSCRIPTIONal
IYN96_02785	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
IYN96_02790	COG1131	(ABC) transporter
IYN96_02795	COG0842	Transport permease protein
IYN96_02805	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IYN96_02825	COG3039	Transposase
IYN96_02835	COG2951	lytic endotransglycosylase activity
IYN96_02855	COG2826	transposase and inactivated derivatives, IS30 family
IYN96_02870	COG3039	Transposase
IYN96_02955	COG2353	YceI-like domain
IYN96_02985	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
IYN96_03085	COG1063	alcohol dehydrogenase
IYN96_03115	COG1294	oxidase, subunit
IYN96_03120	COG1271	oxidase subunit
IYN96_03155	COG2972	Histidine kinase
IYN96_03170	COG0531	amino acid
IYN96_03190	COG3590	peptidase
IYN96_03200	COG0667	Aldo Keto reductase
IYN96_03215	COG3384	dioxygenase
IYN96_03225	COG1573	uracil-dna glycosylase
IYN96_03235	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
IYN96_03240	COG0025	NhaP-type Na H and K H
IYN96_03245	COG1131	(ABC) transporter
IYN96_03250	COG0842	Transport permease protein
IYN96_03265	COG1404	Belongs to the peptidase S8 family
IYN96_03280	COG0745	RESPONSE REGULATOR receiver
IYN96_03330	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IYN96_03355	COG2202	Pas domain
IYN96_03355	COG2205	protein histidine kinase activity
IYN96_03390	COG2813	Specifically methylates the guanine in position
IYN96_03395	COG1187	pseudouridine synthase activity
IYN96_03400	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IYN96_03435	COG0697	spore germination
IYN96_03445	COG2011	ABC-type metal ion transport system permease component
IYN96_03480	COG0508	dehydrogenase complex catalyzes the overall conversion of
IYN96_03490	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IYN96_03510	COG0356	it plays a direct role in the translocation of protons across the membrane
IYN96_03520	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IYN96_03530	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IYN96_03535	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IYN96_03540	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IYN96_03565	COG4191	Histidine kinase
IYN96_03575	COG0577	efflux transmembrane transporter activity
IYN96_03575	COG1136	(ABC) transporter
IYN96_03580	COG1136	(ABC) transporter
IYN96_03580	COG0577	efflux transmembrane transporter activity
IYN96_03595	COG1136	(ABC) transporter
IYN96_03600	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IYN96_03605	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IYN96_03655	COG0339	signal peptide processing
IYN96_03680	COG0546	phosphoglycolate phosphatase activity
IYN96_03690	COG1956	GAF domain-containing protein
IYN96_03695	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
IYN96_03705	COG0720	synthase
IYN96_03710	COG0513	Belongs to the DEAD box helicase family
IYN96_03720	COG0625	glutathione transferase activity
IYN96_03750	COG0626	cystathionine gamma-synthase activity
IYN96_03765	COG0110	maltose O-acetyltransferase activity
IYN96_03770	COG1216	Glycosyl transferase, family 2
IYN96_03770	COG0438	transferase activity, transferring glycosyl groups
IYN96_03775	COG3754	Rhamnan synthesis protein F
IYN96_03785	COG2226	methyltransferase
IYN96_03805	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IYN96_03820	COG0277	FAD linked oxidase domain protein
IYN96_03825	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
IYN96_03825	COG0546	phosphoglycolate phosphatase activity
IYN96_03840	COG2086	electron transfer activity
IYN96_03865	COG0662	Cupin 2, conserved barrel domain protein
IYN96_03865	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
IYN96_03870	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IYN96_03905	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
IYN96_03905	COG3218	ABC-type transport auxiliary lipoprotein component
IYN96_03910	COG1127	ABC transporter
IYN96_03915	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
IYN96_03930	COG0442	prolyl-tRNA aminoacylation
IYN96_03940	COG1183	phosphatidylcholine synthase activity
IYN96_03970	COG0525	valine-tRNA ligase activity
IYN96_03985	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IYN96_03995	COG0795	lipopolysaccharide-transporting ATPase activity
IYN96_04010	COG4974	Belongs to the 'phage' integrase family
IYN96_04015	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IYN96_04020	COG0047	phosphoribosylformylglycinamidine synthase activity
IYN96_04020	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IYN96_04025	COG5295	Hep Hag repeat protein
IYN96_04030	COG1404	Belongs to the peptidase S8 family
IYN96_04035	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IYN96_04045	COG1459	type II secretion system
IYN96_04050	COG2165	general secretion pathway protein
IYN96_04055	COG4970	Tfp pilus assembly protein FimT
IYN96_04060	COG2165	general secretion pathway protein
IYN96_04065	COG4795	General secretion pathway protein
IYN96_04070	COG3156	type II secretion system protein K
IYN96_04075	COG3166	PFAM Fimbrial assembly family protein
IYN96_04090	COG1450	Type ii and iii secretion system protein
IYN96_04105	COG2188	Transcriptional regulator
IYN96_04155	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IYN96_04175	COG0242	peptide deformylase activity
IYN96_04210	COG1228	amidohydrolase
IYN96_04215	COG3964	amidohydrolase
IYN96_04235	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
IYN96_04240	COG0726	polysaccharide deacetylase
IYN96_04260	COG0436	Aminotransferase
IYN96_04290	COG2211	Major facilitator Superfamily
IYN96_04300	COG1609	Transcriptional regulator
IYN96_04305	COG1028	Short-chain dehydrogenase reductase Sdr
IYN96_04310	COG2851	Citrate transporter
IYN96_04325	COG0642	Histidine kinase
IYN96_04335	COG2197	response regulator
IYN96_04350	COG0583	DNA-binding transcription factor activity
IYN96_04365	COG4191	Histidine kinase
IYN96_04385	COG0280	phosphate acetyltransferase
IYN96_04385	COG0281	malic enzyme
IYN96_04410	COG1560	Kdo2-lipid A biosynthetic process
IYN96_04415	COG1519	Transferase
IYN96_04420	COG3039	Transposase
IYN96_04425	COG1538	Outer membrane efflux protein
IYN96_04430	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
IYN96_04450	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IYN96_04455	COG0066	3-isopropylmalate dehydratase activity
IYN96_04460	COG2226	methyltransferase
IYN96_04490	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IYN96_04505	COG3710	Transcriptional regulator
IYN96_04530	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
IYN96_04540	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
IYN96_04575	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IYN96_04585	COG3781	membrane
IYN96_04605	COG1028	Short-chain dehydrogenase reductase Sdr
IYN96_04625	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IYN96_04630	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IYN96_04685	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
IYN96_04695	COG0352	thiamine-phosphate diphosphorylase activity
IYN96_04700	COG1773	rubredoxin
IYN96_04705	COG2912	Transglutaminase-like superfamily
IYN96_04725	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IYN96_04750	COG0006	proline dipeptidase activity
IYN96_04785	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IYN96_04795	COG0346	lactoylglutathione lyase activity
IYN96_04800	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
IYN96_04805	COG1561	YicC-like family, N-terminal region
IYN96_04825	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IYN96_04835	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IYN96_04865	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
IYN96_04900	COG0714	Associated with various cellular activities
IYN96_04920	COG2304	oxidoreductase activity
IYN96_04955	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IYN96_05055	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
IYN96_05060	COG4149	molybdate abc transporter
IYN96_05065	COG0725	ABC transporter, periplasmic molybdate-binding protein
IYN96_05070	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IYN96_05070	COG3453	Protein conserved in bacteria
IYN96_05080	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IYN96_05095	COG0126	phosphoglycerate kinase activity
IYN96_05105	COG0469	pyruvate kinase activity
IYN96_05110	COG3588	fructose-bisphosphate aldolase
IYN96_05115	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
IYN96_05130	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
IYN96_05130	COG1648	precorrin-2 dehydrogenase activity
IYN96_05155	COG0784	Response regulator, receiver
IYN96_05155	COG2198	Histidine kinase
IYN96_05155	COG2205	protein histidine kinase activity
IYN96_05175	COG0175	sulfate reduction
IYN96_05180	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IYN96_05185	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
IYN96_05190	COG0175	sulfate reduction
IYN96_05195	COG0529	Catalyzes the synthesis of activated sulfate
IYN96_05195	COG2895	sulfate adenylyltransferase (ATP) activity
IYN96_05205	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IYN96_05210	COG0308	aminopeptidase N
IYN96_05235	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IYN96_05260	COG1970	mechanosensitive ion channel activity
IYN96_05285	COG0471	metal ion transport
IYN96_05285	COG3273	potassium ion transport
IYN96_05295	COG2022	thiamine diphosphate biosynthetic process
IYN96_05315	COG3039	Transposase
IYN96_05335	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IYN96_05345	COG2003	Belongs to the UPF0758 family
IYN96_05380	COG0084	hydrolase, TatD family'
IYN96_05400	COG3039	Transposase
IYN96_05455	COG0745	RESPONSE REGULATOR receiver
IYN96_05485	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
IYN96_05495	COG4969	Belongs to the N-Me-Phe pilin family
IYN96_05500	COG2194	sulfuric ester hydrolase activity
IYN96_05540	COG0045	succinate-CoA ligase (ADP-forming) activity
IYN96_05545	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
IYN96_05560	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
IYN96_05560	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IYN96_05565	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IYN96_05570	COG0564	pseudouridine synthase activity
IYN96_05585	COG3011	Protein conserved in bacteria
IYN96_05590	COG0840	transmembrane signaling receptor activity
IYN96_05605	COG3387	PFAM Glycoside hydrolase 15-related
IYN96_05610	COG1877	trehalose-phosphatase activity
IYN96_05650	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
IYN96_05665	COG1595	DNA-templated transcription, initiation
IYN96_05675	COG1946	Acyl-CoA thioesterase
IYN96_05690	COG0824	Thioesterase
IYN96_05695	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
IYN96_05705	COG0211	Belongs to the bacterial ribosomal protein bL27 family
IYN96_05710	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IYN96_05715	COG0268	Binds directly to 16S ribosomal RNA
IYN96_05720	COG0728	peptidoglycan biosynthetic process
IYN96_05725	COG0196	riboflavin kinase activity
IYN96_05735	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IYN96_05740	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
IYN96_05755	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IYN96_05760	COG1845	cytochrome c oxidase, subunit III
IYN96_05765	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
IYN96_05830	COG2826	transposase and inactivated derivatives, IS30 family
IYN96_05840	COG3039	Transposase
IYN96_05885	COG2207	Transcriptional regulator
IYN96_05890	COG0326	Molecular chaperone. Has ATPase activity
IYN96_05900	COG1366	Belongs to the anti-sigma-factor antagonist family
IYN96_05905	COG1366	Belongs to the anti-sigma-factor antagonist family
IYN96_05910	COG2172	sigma factor antagonist activity
IYN96_05950	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IYN96_05955	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IYN96_05965	COG2070	2-Nitropropane dioxygenase
IYN96_05975	COG0228	four-way junction DNA binding
IYN96_05980	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IYN96_05985	COG0336	Belongs to the RNA methyltransferase TrmD family
IYN96_06000	COG0534	Mate efflux family protein
IYN96_06010	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
IYN96_06035	COG0542	response to heat
IYN96_06090	COG0019	diaminopimelate decarboxylase activity
IYN96_06100	COG2814	Major facilitator Superfamily
IYN96_06105	COG4264	IucA IucC family
IYN96_06115	COG4772	TonB-dependent receptor
IYN96_06130	COG4651	solute:proton antiporter activity
IYN96_06130	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IYN96_06160	COG0488	(ABC) transporter
IYN96_06185	COG2755	lipolytic protein G-D-S-L family
IYN96_06185	COG0657	acetylesterase activity
IYN96_06200	COG0477	Major facilitator Superfamily
IYN96_06215	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
IYN96_06250	COG2255	four-way junction helicase activity
IYN96_06255	COG0824	Thioesterase
IYN96_06275	COG0823	Involved in the tonB-independent uptake of proteins
IYN96_06280	COG2885	chlorophyll binding
IYN96_06290	COG0602	queuosine metabolic process
IYN96_06300	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
IYN96_06330	COG1187	pseudouridine synthase activity
IYN96_06345	COG0514	ATP-dependent DNA helicase (RecQ)
IYN96_06350	COG0783	Belongs to the Dps family
IYN96_06355	COG1643	Atp-dependent helicase
IYN96_06410	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IYN96_06420	COG1215	transferase activity, transferring glycosyl groups
IYN96_06425	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IYN96_06435	COG1199	ATP-dependent helicase activity
IYN96_06455	COG0189	ligase activity
IYN96_06470	COG0835	chemotaxis
IYN96_06475	COG0840	transmembrane signaling receptor activity
IYN96_06480	COG0643	Histidine kinase
IYN96_06480	COG0784	Response regulator, receiver
IYN96_06480	COG2198	Histidine kinase
IYN96_06505	COG2304	oxidoreductase activity
IYN96_06510	COG1446	asparaginase
IYN96_06555	COG3537	Alpha-1,2-mannosidase
IYN96_06570	COG2826	transposase and inactivated derivatives, IS30 family
IYN96_06585	COG1472	Belongs to the glycosyl hydrolase 3 family
IYN96_06595	COG3525	Glycosyl hydrolase, family 20, catalytic domain
IYN96_06600	COG3858	chitin binding
IYN96_06600	COG1388	LysM domain
IYN96_06615	COG0837	glucose binding
IYN96_06620	COG1385	rRNA (uridine-N3-)-methyltransferase activity
IYN96_06630	COG0494	nUDIX hydrolase
IYN96_06640	COG3956	TIGRFAM MazG family protein
IYN96_06645	COG1742	UPF0060 membrane protein
IYN96_06655	COG0330	HflC and HflK could
IYN96_06670	COG0509	glycine decarboxylation via glycine cleavage system
IYN96_06685	COG3039	Transposase
IYN96_06700	COG3039	Transposase
IYN96_06715	COG1960	acyl-CoA dehydrogenase activity
IYN96_06725	COG1309	transcriptional regulator
IYN96_06730	COG4771	TonB-dependent receptor
IYN96_06740	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IYN96_06750	COG0463	Glycosyl transferase, family 2
IYN96_06755	COG0517	IMP dehydrogenase activity
IYN96_06755	COG0516	GMP reductase activity
IYN96_06765	COG1272	protein, Hemolysin III
IYN96_06775	COG0739	heme binding
IYN96_06780	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IYN96_06785	COG0626	cystathionine gamma-synthase activity
IYN96_06795	COG1760	l-serine dehydratase
IYN96_06820	COG2353	YceI-like domain
IYN96_06825	COG0784	Response regulator, receiver
IYN96_06825	COG2198	Histidine kinase
IYN96_06825	COG2205	protein histidine kinase activity
IYN96_06830	COG5002	protein histidine kinase activity
IYN96_06830	COG0784	Response regulator, receiver
IYN96_06870	COG3867	Arabinogalactan endo-beta-1,4-galactanase
IYN96_06890	COG1960	acyl-CoA dehydrogenase activity
IYN96_06915	COG1250	3-hydroxyacyl-CoA dehydrogenase
IYN96_06915	COG1024	Enoyl-CoA hydratase
IYN96_06930	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IYN96_06935	COG0481	GTPase activity
IYN96_06940	COG0681	Belongs to the peptidase S26 family
IYN96_06960	COG1381	Involved in DNA repair and RecF pathway recombination
IYN96_06975	COG2954	triphosphatase activity
IYN96_06980	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
IYN96_06985	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
IYN96_06990	COG3046	protein related to deoxyribodipyrimidine photolyase
IYN96_07000	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
IYN96_07005	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
IYN96_07010	COG1278	Cold shock
IYN96_07030	COG1201	RNA secondary structure unwinding
IYN96_07035	COG1793	dna ligase
IYN96_07045	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
IYN96_07045	COG1793	dna ligase
IYN96_07060	COG3706	GGDEF domain
IYN96_07075	COG0183	Belongs to the thiolase family
IYN96_07095	COG1451	nucleotide metabolic process
IYN96_07110	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
IYN96_07150	COG1047	Peptidyl-prolyl cis-trans
IYN96_07160	COG2824	Alkylphosphonate utilization operon protein PhnA
IYN96_07170	COG1902	pentaerythritol trinitrate reductase activity
IYN96_07175	COG2814	Major facilitator Superfamily
IYN96_07210	COG0392	lysyltransferase activity
IYN96_07210	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IYN96_07220	COG0251	oxidation-reduction process
IYN96_07225	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IYN96_07240	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IYN96_07265	COG1595	DNA-templated transcription, initiation
IYN96_07280	COG2878	Part of a membrane complex involved in electron transport
IYN96_07290	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IYN96_07290	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IYN96_07300	COG0346	lactoylglutathione lyase activity
IYN96_07305	COG0833	amino acid
IYN96_07310	COG2040	homocysteine
IYN96_07325	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
IYN96_07345	COG1695	Transcriptional regulator
IYN96_07370	COG1981	membrane
IYN96_07395	COG0825	malonyl-CoA metabolic process
IYN96_07415	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IYN96_07420	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
IYN96_07425	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IYN96_07430	COG3039	Transposase
IYN96_07445	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
IYN96_07450	COG0575	Belongs to the CDS family
IYN96_07460	COG0233	cytoplasmic translational termination
IYN96_07475	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IYN96_07535	COG1393	Belongs to the ArsC family
IYN96_07545	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IYN96_07550	COG0367	asparagine synthase
IYN96_07560	COG4774	siderophore transport
IYN96_07580	COG2207	Transcriptional regulator
IYN96_07595	COG1566	PFAM secretion protein HlyD family protein
IYN96_07600	COG2814	Major facilitator Superfamily
IYN96_07705	COG0386	Belongs to the glutathione peroxidase family
IYN96_07770	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
IYN96_07775	COG0084	hydrolase, TatD family'
IYN96_07790	COG1960	acyl-CoA dehydrogenase activity
IYN96_07805	COG0367	asparagine synthase
IYN96_07815	COG0305	Participates in initiation and elongation during chromosome replication
IYN96_07820	COG0415	Belongs to the DNA photolyase family
IYN96_07835	COG1028	Short-chain dehydrogenase reductase Sdr
IYN96_07855	COG3706	GGDEF domain
IYN96_07870	COG0489	protein tyrosine kinase activity
IYN96_07875	COG0717	Belongs to the dCTP deaminase family
IYN96_07900	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IYN96_07915	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IYN96_07935	COG0433	COG0433 Predicted ATPase
IYN96_07960	COG2890	protein-(glutamine-N5) methyltransferase activity
IYN96_07965	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IYN96_07970	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IYN96_07975	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IYN96_07995	COG0101	tRNA pseudouridine synthase activity
IYN96_08000	COG0135	phosphoribosylanthranilate isomerase activity
IYN96_08010	COG0133	tryptophan synthase activity
IYN96_08025	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IYN96_08030	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IYN96_08070	COG0149	triose-phosphate isomerase activity
IYN96_08085	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IYN96_08095	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IYN96_08100	COG0649	NAD binding
IYN96_08105	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
IYN96_08110	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
IYN96_08115	COG1034	ATP synthesis coupled electron transport
IYN96_08120	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
IYN96_08150	COG1007	ATP synthesis coupled electron transport
IYN96_08160	COG0779	Required for maturation of 30S ribosomal subunits
IYN96_08165	COG0195	Participates in both transcription termination and antitermination
IYN96_08170	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IYN96_08185	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IYN96_08190	COG1185	polyribonucleotide nucleotidyltransferase activity
IYN96_08225	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
IYN96_08235	COG2095	MarC family integral membrane protein
IYN96_08250	COG1611	Belongs to the LOG family
IYN96_08345	COG4974	Belongs to the 'phage' integrase family
IYN96_08350	COG4969	Belongs to the N-Me-Phe pilin family
IYN96_08355	COG0556	nucleotide-excision repair
IYN96_08390	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
IYN96_08400	COG2986	histidine ammonia-lyase
IYN96_08405	COG1228	amidohydrolase
IYN96_08445	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
IYN96_08450	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
IYN96_08455	COG0077	Prephenate dehydratase
IYN96_08455	COG1605	Chorismate mutase
IYN96_08460	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
IYN96_08480	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IYN96_08485	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IYN96_08490	COG0583	DNA-binding transcription factor activity
IYN96_08530	COG3039	Transposase
IYN96_08560	COG0840	transmembrane signaling receptor activity
IYN96_08575	COG0784	Response regulator, receiver
IYN96_08575	COG5002	protein histidine kinase activity
IYN96_08575	COG2205	protein histidine kinase activity
IYN96_08580	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
IYN96_08590	COG0784	Response regulator, receiver
IYN96_08590	COG4191	Histidine kinase
IYN96_08610	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IYN96_08630	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IYN96_08645	COG1595	DNA-templated transcription, initiation
IYN96_08695	COG2244	polysaccharide biosynthetic process
IYN96_08725	COG2264	protein methyltransferase activity
IYN96_08735	COG0438	transferase activity, transferring glycosyl groups
IYN96_08755	COG1132	(ABC) transporter
IYN96_08765	COG2271	Major facilitator Superfamily
IYN96_08775	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IYN96_08790	COG1253	flavin adenine dinucleotide binding
IYN96_08825	COG0504	CTP synthase activity
IYN96_08830	COG2877	3-deoxy-8-phosphooctulonate synthase activity
IYN96_08840	COG0148	phosphopyruvate hydratase activity
IYN96_08845	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
IYN96_08860	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
IYN96_08875	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
IYN96_08880	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
IYN96_08885	COG1238	metal cluster binding
IYN96_08900	COG1534	Rna-binding protein
IYN96_08905	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
IYN96_08915	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IYN96_08930	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IYN96_08935	COG1546	Belongs to the CinA family
IYN96_08950	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IYN96_08955	COG2137	regulation of response to DNA damage stimulus
IYN96_08960	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IYN96_08965	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
IYN96_08980	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IYN96_09010	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
IYN96_09035	COG2166	iron-sulfur cluster assembly
IYN96_09050	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IYN96_09055	COG0137	argininosuccinate synthase activity
IYN96_09065	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IYN96_09070	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
IYN96_09085	COG0165	Argininosuccinate lyase
IYN96_09135	COG1271	oxidase subunit
IYN96_09145	COG4988	ABC transporter
IYN96_09150	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
IYN96_09210	COG4133	protoheme IX ABC transporter activity
IYN96_09215	COG0436	Aminotransferase
IYN96_09235	COG1187	pseudouridine synthase activity
IYN96_09240	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IYN96_09245	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IYN96_09250	COG2350	Protein conserved in bacteria
IYN96_09280	COG1175	transmembrane transport
IYN96_09285	COG0395	ABC-type sugar transport system, permease component
IYN96_09310	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IYN96_09320	COG2957	Belongs to the agmatine deiminase family
IYN96_09335	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
IYN96_09340	COG0539	negative regulation of cytoplasmic translation
IYN96_09345	COG0776	regulation of translation
IYN96_09355	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
IYN96_09360	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IYN96_09370	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IYN96_09385	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IYN96_09395	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IYN96_09395	COG0519	Catalyzes the synthesis of GMP from XMP
IYN96_09400	COG3002	Belongs to the UPF0753 family
IYN96_09405	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IYN96_09410	COG0583	DNA-binding transcription factor activity
IYN96_09435	COG0583	DNA-binding transcription factor activity
IYN96_09440	COG0583	DNA-binding transcription factor activity
IYN96_09460	COG1914	H( )-stimulated, divalent metal cation uptake system
IYN96_09480	COG0668	transmembrane transport
IYN96_09505	COG1028	Short-chain dehydrogenase reductase Sdr
IYN96_09510	COG1183	phosphatidylcholine synthase activity
IYN96_09520	COG3243	poly(R)-hydroxyalkanoic acid synthase
IYN96_09535	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IYN96_09535	COG0723	plastoquinol--plastocyanin reductase activity
IYN96_09545	COG2183	response to ionizing radiation
IYN96_09555	COG0784	Response regulator, receiver
IYN96_09555	COG2205	protein histidine kinase activity
IYN96_09670	COG3039	Transposase
IYN96_09675	COG0800	Aldolase
IYN96_09680	COG0129	dihydroxy-acid dehydratase activity
IYN96_09685	COG0363	glucosamine-6-phosphate deaminase activity
IYN96_09695	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IYN96_09710	COG0354	folic acid binding
IYN96_09725	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
IYN96_09740	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
IYN96_09755	COG4591	ABC-type transport system involved in lipoprotein release permease component
IYN96_09780	COG0811	peptide transport
IYN96_09795	COG1663	tetraacyldisaccharide 4'-kinase activity
IYN96_09805	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IYN96_09815	COG0322	excinuclease ABC activity
IYN96_09845	COG2826	transposase and inactivated derivatives, IS30 family
IYN96_09870	COG3039	Transposase
IYN96_09910	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
IYN96_09930	COG1054	Belongs to the UPF0176 family
IYN96_09940	COG1530	ribonuclease E activity
IYN96_09950	COG3064	Membrane
IYN96_09970	COG2154	pterin-4-alpha-carbinolamine dehydratase
IYN96_10055	COG3039	Transposase
IYN96_10215	COG0631	protein serine/threonine phosphatase activity
IYN96_10220	COG0515	serine threonine protein kinase
IYN96_10250	COG1858	cytochrome C peroxidase
IYN96_10300	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IYN96_10305	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IYN96_10360	COG2201	protein-glutamate methylesterase activity
IYN96_10400	COG4566	intracellular signal transduction
IYN96_10410	COG5001	Diguanylate cyclase
IYN96_10460	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
IYN96_10460	COG1648	precorrin-2 dehydrogenase activity
IYN96_10485	COG0746	molybdenum cofactor guanylyltransferase activity
IYN96_10515	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
IYN96_10530	COG0303	'Molybdopterin
IYN96_10535	COG1160	GTP binding
IYN96_10540	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IYN96_10560	COG0820	rRNA (adenine-C2-)-methyltransferase activity
IYN96_10575	COG1024	Enoyl-CoA hydratase
IYN96_10575	COG1250	3-hydroxyacyl-CoA dehydrogenase
IYN96_10580	COG0183	Belongs to the thiolase family
IYN96_10585	COG0038	chloride channel
IYN96_10605	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
IYN96_10625	COG1674	ftsk spoiiie
IYN96_10630	COG0492	ferredoxin-NADP+ reductase activity
IYN96_10655	COG0542	response to heat
IYN96_10670	COG0482	sulfurtransferase activity
IYN96_10700	COG4585	Histidine kinase
IYN96_10710	COG4191	Histidine kinase
IYN96_10730	COG0784	Response regulator, receiver
IYN96_10730	COG0835	chemotaxis
IYN96_10740	COG1558	bacterial-type flagellum-dependent cell motility
IYN96_10745	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
IYN96_10755	COG4787	bacterial-type flagellum-dependent cell motility
IYN96_10775	COG3951	Flagellar rod assembly protein muramidase FlgJ
IYN96_10775	COG1705	Flagellar rod assembly protein muramidase FlgJ
IYN96_10790	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IYN96_10795	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
IYN96_10825	COG2201	protein-glutamate methylesterase activity
IYN96_10845	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IYN96_10850	COG4221	oxidoreductase activity
IYN96_10855	COG1028	Short-chain dehydrogenase reductase Sdr
IYN96_10890	COG1677	Flagellar hook-basal body complex protein FliE
IYN96_10940	COG3190	flagellar
IYN96_10955	COG1684	flagellar biosynthetic protein fliR
IYN96_11010	COG2198	Histidine kinase
IYN96_11010	COG0784	Response regulator, receiver
IYN96_11010	COG0643	Histidine kinase
IYN96_11125	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IYN96_11140	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
IYN96_11145	COG1360	Flagellar Motor Protein
IYN96_11150	COG1192	Involved in chromosome partitioning
IYN96_11155	COG0835	chemotaxis
IYN96_11165	COG0745	RESPONSE REGULATOR receiver
IYN96_11175	COG0840	transmembrane signaling receptor activity
IYN96_11200	COG0840	transmembrane signaling receptor activity
IYN96_11205	COG0840	transmembrane signaling receptor activity
IYN96_11210	COG0840	transmembrane signaling receptor activity
IYN96_11220	COG0840	transmembrane signaling receptor activity
IYN96_11225	COG0840	transmembrane signaling receptor activity
IYN96_11230	COG0840	transmembrane signaling receptor activity
IYN96_11235	COG0840	transmembrane signaling receptor activity
IYN96_11240	COG0840	transmembrane signaling receptor activity
IYN96_11255	COG0835	chemotaxis
IYN96_11265	COG0840	transmembrane signaling receptor activity
IYN96_11295	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IYN96_11325	COG0318	PFAM AMP-dependent synthetase and ligase
IYN96_11330	COG1024	Enoyl-CoA hydratase
IYN96_11335	COG2205	protein histidine kinase activity
IYN96_11335	COG2198	Histidine kinase
IYN96_11335	COG0784	Response regulator, receiver
IYN96_11355	COG3279	Response regulator of the LytR AlgR family
IYN96_11370	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
IYN96_11380	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IYN96_11385	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
IYN96_11395	COG0505	Belongs to the CarA family
IYN96_11400	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
IYN96_11405	COG2258	MOSC domain
IYN96_11410	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IYN96_11460	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IYN96_11480	COG0277	FAD linked oxidase domain protein
IYN96_11485	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IYN96_11495	COG0531	amino acid
IYN96_11500	COG0531	amino acid
IYN96_11505	COG0235	Class ii aldolase
IYN96_11510	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
IYN96_11530	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
IYN96_11530	COG0140	phosphoribosyl-ATP diphosphatase activity
IYN96_11540	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
IYN96_11550	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
IYN96_11550	COG0131	Imidazoleglycerol-phosphate dehydratase
IYN96_11565	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
IYN96_11580	COG0124	histidyl-tRNA synthetase
IYN96_11595	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
IYN96_11650	COG1012	belongs to the aldehyde dehydrogenase family
IYN96_11670	COG0812	UDP-N-acetylmuramate dehydrogenase activity
IYN96_11675	COG0697	spore germination
IYN96_11680	COG1794	racemase activity, acting on amino acids and derivatives
IYN96_11695	COG0671	phosphoesterase, PA-phosphatase related
IYN96_11710	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
IYN96_11715	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
IYN96_11725	COG3706	GGDEF domain
IYN96_11725	COG2203	Gaf domain
IYN96_11725	COG4251	negative regulation of phosphorylation
IYN96_11725	COG5001	Diguanylate cyclase
IYN96_11740	COG1472	Belongs to the glycosyl hydrolase 3 family
IYN96_11765	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
IYN96_11785	COG0617	tRNA 3'-terminal CCA addition
IYN96_11795	COG1469	GTP cyclohydrolase I activity
IYN96_11800	COG0860	N-Acetylmuramoyl-L-alanine amidase
IYN96_11810	COG0477	Major facilitator Superfamily
IYN96_11820	COG1070	Carbohydrate kinase
IYN96_11845	COG0800	Aldolase
IYN96_11850	COG4948	Mandelate Racemase Muconate Lactonizing
IYN96_11860	COG3734	2-keto-3-deoxy-galactonokinase
IYN96_11865	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
IYN96_11875	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IYN96_11890	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IYN96_11895	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
IYN96_11905	COG0352	thiamine-phosphate diphosphorylase activity
IYN96_11905	COG0351	phosphomethylpyrimidine kinase
IYN96_11930	COG0583	DNA-binding transcription factor activity
IYN96_11935	COG1741	Belongs to the pirin family
IYN96_11980	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IYN96_11985	COG0402	S-adenosylhomocysteine deaminase activity
IYN96_12000	COG1509	lysine 2,3-aminomutase activity
IYN96_12005	COG3300	MHYT domain
IYN96_12005	COG5001	Diguanylate cyclase
IYN96_12020	COG0483	inositol monophosphate 1-phosphatase activity
IYN96_12025	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IYN96_12050	COG0488	(ABC) transporter
IYN96_12055	COG0513	Belongs to the DEAD box helicase family
IYN96_12065	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
IYN96_12075	COG0625	glutathione transferase activity
IYN96_12080	COG1278	Cold shock
IYN96_12085	COG1671	Belongs to the UPF0178 family
IYN96_12090	COG4681	YaeQ
IYN96_12095	COG2081	HI0933 family
IYN96_12115	COG1028	Short-chain dehydrogenase reductase Sdr
IYN96_12135	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IYN96_12140	COG0860	N-Acetylmuramoyl-L-alanine amidase
IYN96_12145	COG0802	atpase or kinase
IYN96_12150	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
IYN96_12150	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IYN96_12155	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IYN96_12175	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IYN96_12245	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IYN96_12340	COG2801	Transposase and inactivated derivatives
IYN96_12355	COG0835	chemotaxis
IYN96_12360	COG0840	transmembrane signaling receptor activity
IYN96_12385	COG2969	positive regulation of protein catabolic process
IYN96_12390	COG0625	glutathione transferase activity
IYN96_12395	COG2857	Cytochrome c1
IYN96_12400	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
IYN96_12405	COG0723	plastoquinol--plastocyanin reductase activity
IYN96_12410	COG0741	lytic transglycosylase activity
IYN96_12435	COG1702	phosphate starvation-inducible protein PhoH
IYN96_12455	COG4535	Mg2 and Co2 transporter CorC
IYN96_12470	COG1012	belongs to the aldehyde dehydrogenase family
IYN96_12475	COG1177	transmembrane transport
IYN96_12480	COG1176	ABC-type spermidine putrescine transport system, permease component I
IYN96_12490	COG3842	ATPase activity
IYN96_12510	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
IYN96_12590	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
IYN96_12595	COG0174	glutamine synthetase
IYN96_12600	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IYN96_12610	COG0477	Major facilitator Superfamily
IYN96_12620	COG0243	molybdopterin cofactor binding
IYN96_12640	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
IYN96_12645	COG1121	(ABC) transporter
IYN96_12655	COG2733	membrane
IYN96_12660	COG2205	protein histidine kinase activity
IYN96_12660	COG5002	protein histidine kinase activity
IYN96_12660	COG0784	Response regulator, receiver
IYN96_12675	COG0477	Major facilitator Superfamily
IYN96_12685	COG2902	Dehydrogenase
IYN96_12695	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IYN96_12700	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IYN96_12710	COG1609	Transcriptional regulator
IYN96_12715	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IYN96_12715	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
IYN96_12720	COG1105	Belongs to the carbohydrate kinase PfkB family
IYN96_12725	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IYN96_12725	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IYN96_12735	COG3039	Transposase
IYN96_12775	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IYN96_12785	COG1862	Preprotein translocase
IYN96_12790	COG0343	queuine tRNA-ribosyltransferase activity
IYN96_12845	COG0405	Gamma-glutamyltransferase
IYN96_12850	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IYN96_12860	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IYN96_12865	COG0742	ribosomal rna small subunit methyltransferase
IYN96_12870	COG0326	Molecular chaperone. Has ATPase activity
IYN96_12910	COG4206	TonB-dependent receptor
IYN96_12960	COG0531	amino acid
IYN96_12975	COG0006	proline dipeptidase activity
IYN96_12985	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IYN96_13000	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IYN96_13005	COG3938	Belongs to the proline racemase family
IYN96_13015	COG0552	protein localization to endoplasmic reticulum
IYN96_13025	COG1194	a g-specific adenine glycosylase
IYN96_13035	COG0784	Response regulator, receiver
IYN96_13035	COG4191	Histidine kinase
IYN96_13040	COG3039	Transposase
IYN96_13045	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IYN96_13065	COG3040	lipid binding
IYN96_13075	COG1960	acyl-CoA dehydrogenase activity
IYN96_13085	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IYN96_13115	COG0438	transferase activity, transferring glycosyl groups
IYN96_13125	COG0438	transferase activity, transferring glycosyl groups
IYN96_13130	COG0438	transferase activity, transferring glycosyl groups
IYN96_13185	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IYN96_13200	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IYN96_13220	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
IYN96_13235	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
IYN96_13255	COG3115	cell septum assembly
IYN96_13275	COG0360	Binds together with S18 to 16S ribosomal RNA
IYN96_13280	COG0316	Belongs to the HesB IscA family
IYN96_13310	COG0288	reversible hydration of carbon dioxide
IYN96_13325	COG3844	kynureninase activity
IYN96_13335	COG2925	Exonuclease
IYN96_13345	COG0667	Aldo Keto reductase
IYN96_13370	COG0116	Belongs to the methyltransferase superfamily
IYN96_13370	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
IYN96_13415	COG0494	nUDIX hydrolase
IYN96_13425	COG1024	Enoyl-CoA hydratase
IYN96_13435	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IYN96_13465	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
IYN96_13470	COG0573	inorganic phosphate transmembrane transporter activity
IYN96_13485	COG0704	Plays a role in the regulation of phosphate uptake
IYN96_13495	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IYN96_13505	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IYN96_13520	COG0557	exoribonuclease II activity
IYN96_13545	COG1960	acyl-CoA dehydrogenase activity
IYN96_13550	COG2226	methyltransferase
IYN96_13570	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IYN96_13580	COG1609	Transcriptional regulator
IYN96_13595	COG2900	Belongs to the SlyX family
IYN96_13610	COG0386	Belongs to the glutathione peroxidase family
IYN96_13620	COG1725	Transcriptional regulator
IYN96_13625	COG1131	(ABC) transporter
IYN96_13685	COG2850	peptidyl-arginine hydroxylation
IYN96_13725	COG1132	(ABC) transporter
IYN96_13735	COG0583	DNA-binding transcription factor activity
IYN96_13760	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
IYN96_13765	COG0484	heat shock protein binding
IYN96_13770	COG0443	Heat shock 70 kDa protein
IYN96_13775	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IYN96_13785	COG0497	DNA recombination
IYN96_13795	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IYN96_13800	COG2914	Belongs to the UPF0125 (RnfH) family
IYN96_13810	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
IYN96_13890	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IYN96_13895	COG2311	Membrane
IYN96_13900	COG1047	Peptidyl-prolyl cis-trans
IYN96_13905	COG0791	NLP P60 protein
IYN96_13910	COG0791	NLP P60 protein
IYN96_13925	COG4106	trans-aconitate 2-methyltransferase activity
IYN96_13930	COG1301	dicarboxylic acid transport
IYN96_13935	COG1785	Belongs to the alkaline phosphatase family
IYN96_13940	COG0037	tRNA processing
IYN96_13945	COG1722	exodeoxyribonuclease VII activity
IYN96_13950	COG0142	geranyltranstransferase activity
IYN96_13955	COG4104	PAAR repeat-containing protein
IYN96_13975	COG0312	modulator of DNA gyrase
IYN96_13980	COG3028	Belongs to the UPF0307 family
IYN96_13985	COG0312	modulator of DNA gyrase
IYN96_13995	COG3164	Protein of unknown function
IYN96_14010	COG2968	Membrane
IYN96_14035	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IYN96_14055	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IYN96_14080	COG3118	belongs to the thioredoxin family
IYN96_14145	COG1132	(ABC) transporter
IYN96_14175	COG0745	RESPONSE REGULATOR receiver
IYN96_14180	COG5002	protein histidine kinase activity
IYN96_14180	COG5000	phosphorelay sensor kinase activity
IYN96_14185	COG0475	glutathione-regulated potassium exporter activity
IYN96_14195	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
IYN96_14215	COG1187	pseudouridine synthase activity
IYN96_14220	COG5001	Diguanylate cyclase
IYN96_14220	COG5002	protein histidine kinase activity
IYN96_14270	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
IYN96_14345	COG0735	belongs to the Fur family
IYN96_14350	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IYN96_14395	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IYN96_14410	COG0643	Histidine kinase
IYN96_14410	COG2198	Histidine kinase
IYN96_14415	COG0840	transmembrane signaling receptor activity
IYN96_14420	COG0835	chemotaxis
IYN96_14425	COG2200	EAL domain
IYN96_14425	COG2202	Pas domain
IYN96_14425	COG2199	diguanylate cyclase activity
IYN96_14430	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
IYN96_14515	COG1515	deoxyribonuclease V activity
IYN96_14525	COG1741	Belongs to the pirin family
IYN96_14630	COG1741	Belongs to the pirin family
IYN96_14635	COG1966	Carbon starvation protein
IYN96_14640	COG2879	small protein
IYN96_14700	COG1529	Aldehyde oxidase and xanthine dehydrogenase
IYN96_14705	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
IYN96_14710	COG2080	2 iron, 2 sulfur cluster binding
IYN96_14720	COG5001	Diguanylate cyclase
IYN96_14720	COG4251	negative regulation of phosphorylation
IYN96_14720	COG3706	GGDEF domain
IYN96_14720	COG2203	Gaf domain
IYN96_14725	COG0629	single-stranded DNA binding
IYN96_14730	COG0142	geranyltranstransferase activity
IYN96_14755	COG0527	aspartate kinase activity
IYN96_14765	COG0384	phenazine biosynthesis protein PhzF
IYN96_14775	COG1764	response to oxidative stress
IYN96_14790	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IYN96_14795	COG1678	Uncharacterized ACR, COG1678
IYN96_14805	COG0519	Catalyzes the synthesis of GMP from XMP
IYN96_14835	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IYN96_14890	COG1959	2 iron, 2 sulfur cluster binding
IYN96_14895	COG0719	Fe-S assembly protein
IYN96_14900	COG0396	ATPase activity
IYN96_14905	COG0719	Fe-S assembly protein
IYN96_14910	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IYN96_14920	COG2146	nitrite reductase [NAD(P)H] activity
IYN96_14935	COG1555	photosystem II stabilization
IYN96_14940	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IYN96_14955	COG3178	'Phosphotransferase
IYN96_14960	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
IYN96_14970	COG0628	permease
IYN96_14980	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
IYN96_14995	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IYN96_15015	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IYN96_15020	COG0271	Belongs to the BolA IbaG family
IYN96_15030	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
IYN96_15040	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
IYN96_15045	COG1137	ATPase activity
IYN96_15060	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IYN96_15070	COG1660	Displays ATPase and GTPase activities
IYN96_15080	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IYN96_15085	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IYN96_15100	COG1294	oxidase, subunit
IYN96_15105	COG1271	oxidase subunit
IYN96_15115	COG1113	amino acid transport
IYN96_15130	COG2197	response regulator
IYN96_15135	COG0531	amino acid
IYN96_15190	COG0754	glutathionylspermidine amidase activity
IYN96_15215	COG1842	Phage shock protein A
IYN96_15230	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IYN96_15565	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
IYN96_15590	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
IYN96_15605	COG2197	response regulator
IYN96_15610	COG4585	Histidine kinase
IYN96_15625	COG2894	cell division
IYN96_15630	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
IYN96_15640	COG0642	Histidine kinase
IYN96_15645	COG0745	RESPONSE REGULATOR receiver
IYN96_15650	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IYN96_15660	COG2194	sulfuric ester hydrolase activity
IYN96_15690	COG3551	Protein conserved in bacteria
IYN96_15725	COG0753	catalase activity
IYN96_15760	COG1917	Cupin 2, conserved barrel domain protein
IYN96_15760	COG2207	Transcriptional regulator
IYN96_15770	COG1506	peptidase
IYN96_15770	COG0823	Involved in the tonB-independent uptake of proteins
IYN96_15785	COG1297	OPT oligopeptide transporter protein
IYN96_15800	COG0587	DNA-directed DNA polymerase activity
IYN96_15870	COG0732	type I restriction modification DNA specificity domain
IYN96_15905	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
IYN96_15945	COG1309	transcriptional regulator
IYN96_15960	COG0308	aminopeptidase N
IYN96_15975	COG0330	HflC and HflK could
IYN96_15980	COG0330	HflC and HflK could
IYN96_16000	COG0678	peroxiredoxin activity
IYN96_16060	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IYN96_16075	COG3829	transcription factor binding
IYN96_16105	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IYN96_16110	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IYN96_16120	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IYN96_16125	COG1028	Short-chain dehydrogenase reductase Sdr
IYN96_16150	COG1399	metal-binding, possibly nucleic acid-binding protein
IYN96_16170	COG0714	Associated with various cellular activities
IYN96_16190	COG0537	adenosine 5'-monophosphoramidase activity
IYN96_16200	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
IYN96_16220	COG0314	molybdopterin synthase activity
IYN96_16225	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
IYN96_16230	COG0315	cyclic pyranopterin monophosphate synthase activity
IYN96_16240	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IYN96_16245	COG1234	tRNA 3'-trailer cleavage
IYN96_16250	COG3642	lipopolysaccharide core region biosynthetic process
IYN96_16255	COG0859	PFAM glycosyl transferase family 9
IYN96_16270	COG0631	protein serine/threonine phosphatase activity
IYN96_16275	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IYN96_16300	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IYN96_16340	COG0544	peptidyl-prolyl cis-trans isomerase activity
IYN96_16385	COG0473	3-isopropylmalate dehydrogenase activity
IYN96_16400	COG4783	chaperone-mediated protein folding
IYN96_16415	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
IYN96_16425	COG0438	transferase activity, transferring glycosyl groups
IYN96_16430	COG0671	phosphoesterase, PA-phosphatase related
IYN96_16435	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IYN96_16460	COG2833	Protein of unknown function (DUF455)
IYN96_16480	COG0285	dihydrofolate synthase activity
IYN96_16485	COG0406	alpha-ribazole phosphatase activity
IYN96_16520	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
IYN96_16525	COG4208	sulfate ABC transporter
IYN96_16530	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
IYN96_16535	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
IYN96_16540	COG0156	8-amino-7-oxononanoate synthase activity
IYN96_16565	COG0604	alcohol dehydrogenase
IYN96_16570	COG0446	pyridine nucleotide-disulphide oxidoreductase
IYN96_16570	COG1902	pentaerythritol trinitrate reductase activity
IYN96_16600	COG0584	glycerophosphoryl diester phosphodiesterase
IYN96_16630	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IYN96_16635	COG1217	gtp-binding protein TYPA
IYN96_16655	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
IYN96_16670	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
IYN96_16675	COG0203	ribosomal protein L17
IYN96_16685	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IYN96_16690	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IYN96_16700	COG0201	protein transport
IYN96_16705	COG0200	Binds to the 23S rRNA
IYN96_16710	COG1841	ribosomal large subunit assembly
IYN96_16740	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IYN96_16745	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IYN96_16750	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IYN96_16755	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IYN96_16760	COG0255	Belongs to the universal ribosomal protein uL29 family
IYN96_16765	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IYN96_16775	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IYN96_16785	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IYN96_16790	COG0089	rRNA binding
IYN96_16795	COG0088	Forms part of the polypeptide exit tunnel
IYN96_16805	COG0051	transcription antitermination factor activity, RNA binding
IYN96_16825	COG0049	tRNA binding
IYN96_16830	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IYN96_16835	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IYN96_16840	COG0085	RNA polymerase activity
IYN96_16850	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IYN96_16855	COG0081	regulation of translation
IYN96_16860	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IYN96_16865	COG0250	Participates in transcription elongation, termination and antitermination
IYN96_16870	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
IYN96_16900	COG0012	GTP binding
IYN96_16905	COG0193	aminoacyl-tRNA hydrolase activity
IYN96_16915	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IYN96_16930	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
IYN96_16940	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
IYN96_16945	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IYN96_16955	COG0521	Mo-molybdopterin cofactor biosynthetic process
IYN96_16975	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IYN96_16980	COG1295	ribonuclease BN
IYN96_17015	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IYN96_17025	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IYN96_17080	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
IYN96_17125	COG2890	protein-(glutamine-N5) methyltransferase activity
IYN96_17135	COG3634	alkyl hydroperoxide reductase activity
IYN96_17140	COG0583	DNA-binding transcription factor activity
IYN96_17150	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IYN96_17155	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IYN96_17165	COG2197	response regulator
IYN96_17195	COG0697	spore germination
IYN96_17225	COG3386	PFAM SMP-30 Gluconolaconase
IYN96_17245	COG1024	Enoyl-CoA hydratase
IYN96_17260	COG0583	DNA-binding transcription factor activity
IYN96_17265	COG3384	dioxygenase
IYN96_17295	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IYN96_17300	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IYN96_17310	COG2096	Adenosyltransferase
IYN96_17315	COG0123	including yeast histone deacetylase and acetoin utilization protein
IYN96_17330	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
IYN96_17340	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
IYN96_17345	COG2967	ApaG domain
IYN96_17350	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
IYN96_17370	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IYN96_17390	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
IYN96_17405	COG0642	Histidine kinase
IYN96_17420	COG4181	ATPase activity
IYN96_17430	COG2175	clavaminate synthase activity
IYN96_17445	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IYN96_17465	COG0667	Aldo Keto reductase
IYN96_17475	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IYN96_17480	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IYN96_17490	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IYN96_17505	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IYN96_17545	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
IYN96_17550	COG2226	methyltransferase
IYN96_17595	COG1028	Short-chain dehydrogenase reductase Sdr
IYN96_17595	COG3321	synthase
IYN96_17595	COG0604	alcohol dehydrogenase
IYN96_17605	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
IYN96_17620	COG0494	nUDIX hydrolase
IYN96_17635	COG4942	peptidase
IYN96_17635	COG1388	LysM domain
IYN96_17645	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
IYN96_17665	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
IYN96_17670	COG1181	Belongs to the D-alanine--D-alanine ligase family
IYN96_17675	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IYN96_17690	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IYN96_17695	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
IYN96_17710	COG3116	cell division
IYN96_17715	COG0275	rRNA processing
IYN96_17755	COG0792	nuclease activity
IYN96_17760	COG1988	membrane-bound metal-dependent
IYN96_17765	COG0277	FAD linked oxidase domain protein
IYN96_17770	COG0745	RESPONSE REGULATOR receiver
IYN96_17775	COG2205	protein histidine kinase activity
IYN96_17785	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
IYN96_17790	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
IYN96_17810	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
IYN96_17815	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IYN96_17820	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
IYN96_17840	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IYN96_17840	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IYN96_17855	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IYN96_17865	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IYN96_17885	COG0488	(ABC) transporter
IYN96_17935	COG2205	protein histidine kinase activity
IYN96_17975	COG0218	Necessary for normal cell division and for the maintenance of normal septation
IYN96_18035	COG1649	PFAM Uncharacterised BCR, COG1649
IYN96_18035	COG0726	polysaccharide deacetylase
IYN96_18040	COG1215	transferase activity, transferring glycosyl groups
IYN96_18050	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
IYN96_18055	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IYN96_18060	COG1609	Transcriptional regulator
IYN96_18070	COG2188	Transcriptional regulator
IYN96_18085	COG3250	beta-galactosidase activity
IYN96_18120	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IYN96_18125	COG4191	Histidine kinase
IYN96_18130	COG0784	Response regulator, receiver
IYN96_18135	COG4251	negative regulation of phosphorylation
IYN96_18140	COG2823	Periplasmic or secreted lipoprotein
IYN96_18145	COG0673	inositol 2-dehydrogenase activity
IYN96_18150	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
IYN96_18185	COG1051	belongs to the nudix hydrolase family
IYN96_18185	COG1056	cytidyltransferase-related domain
IYN96_18210	COG2921	Belongs to the UPF0250 family
IYN96_18225	COG1686	Belongs to the peptidase S11 family
IYN96_18230	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
IYN96_18235	COG2951	lytic endotransglycosylase activity
IYN96_18275	COG5632	N-Acetylmuramoyl-L-alanine amidase
IYN96_18275	COG1388	LysM domain
IYN96_18275	COG3409	Peptidoglycan-binding domain 1 protein
IYN96_18290	COG0772	Belongs to the SEDS family
IYN96_18305	COG1792	Involved in formation and maintenance of cell shape
IYN96_18310	COG1077	Cell shape determining protein MreB Mrl
IYN96_18315	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IYN96_18335	COG3300	MHYT domain
IYN96_18335	COG5001	Diguanylate cyclase
IYN96_18380	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
IYN96_18400	COG2832	Protein of unknown function (DUF454)
IYN96_18410	COG0436	Aminotransferase
IYN96_18420	COG1505	serine-type exopeptidase activity
IYN96_18445	COG0181	hydroxymethylbilane synthase activity
IYN96_18455	COG3275	phosphorelay sensor kinase activity
IYN96_18470	COG3039	Transposase
IYN96_18490	COG0659	secondary active sulfate transmembrane transporter activity
IYN96_18570	COG0598	Magnesium transport protein CorA
IYN96_18580	COG1113	amino acid transport
IYN96_18600	COG4305	rare lipoprotein A
IYN96_18605	COG0697	spore germination
IYN96_18660	COG4221	oxidoreductase activity
IYN96_18700	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IYN96_18725	COG0459	protein refolding
IYN96_18755	COG2860	membrane
IYN96_18760	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IYN96_18765	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IYN96_18770	COG2201	protein-glutamate methylesterase activity
IYN96_18775	COG2177	Part of the ABC transporter FtsEX involved in
IYN96_18780	COG2884	Cell division ATP-binding protein ftsE
IYN96_18790	COG3118	belongs to the thioredoxin family
IYN96_18795	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
IYN96_18830	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
IYN96_18830	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
IYN96_18840	COG1473	amidohydrolase
IYN96_18845	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IYN96_18850	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IYN96_18880	COG5383	Protein conserved in bacteria
IYN96_18920	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
IYN96_18925	COG3023	N-Acetylmuramoyl-L-alanine amidase
IYN96_18935	COG4948	Mandelate Racemase Muconate Lactonizing
IYN96_18950	COG0531	amino acid
IYN96_18970	COG4682	membrane
IYN96_18980	COG2133	pyrroloquinoline quinone binding
IYN96_19000	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IYN96_19005	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IYN96_19020	COG1610	YqeY-like protein
IYN96_19035	COG1295	ribonuclease BN
IYN96_19040	COG0358	DNA primase activity
IYN96_19095	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
IYN96_19110	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
IYN96_19165	COG0739	heme binding
IYN96_19180	COG2211	Major facilitator Superfamily
IYN96_19185	COG0708	Exodeoxyribonuclease III
IYN96_19230	COG2111	Na H antiporter
IYN96_19230	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IYN96_19235	COG1006	Multisubunit Na H antiporter MnhC subunit
IYN96_19240	COG0651	ATP synthesis coupled electron transport
IYN96_19250	COG2212	antiporter activity
IYN96_19255	COG1320	monovalent cation:proton antiporter activity
IYN96_19265	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
IYN96_19290	COG3104	oligopeptide transport
IYN96_19295	COG3483	tryptophan 2,3-dioxygenase activity
IYN96_19305	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
IYN96_19320	COG0508	dehydrogenase complex catalyzes the overall conversion of
IYN96_19335	COG3039	Transposase
IYN96_19340	COG0513	Belongs to the DEAD box helicase family
IYN96_19390	COG2801	Transposase and inactivated derivatives
IYN96_19410	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IYN96_19415	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IYN96_19425	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IYN96_19425	COG1042	CoA-binding domain protein
IYN96_19425	COG0045	succinate-CoA ligase (ADP-forming) activity
IYN96_19435	COG2239	Acts as a magnesium transporter
IYN96_19455	COG3039	Transposase
IYN96_19470	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IYN96_19475	COG3387	PFAM Glycoside hydrolase 15-related
IYN96_19490	COG3100	YcgL domain-containing protein
IYN96_19495	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IYN96_19505	COG0463	Glycosyl transferase, family 2
IYN96_19525	COG1028	Short-chain dehydrogenase reductase Sdr
IYN96_19565	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
IYN96_19580	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IYN96_19625	COG0408	coproporphyrinogen oxidase activity
IYN96_19695	COG0210	DNA helicase
IYN96_19710	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IYN96_19715	COG0583	DNA-binding transcription factor activity
IYN96_19720	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
IYN96_19730	COG2159	amidohydrolase
IYN96_19755	COG0357	Ribosomal RNA small subunit methyltransferase G
IYN96_19760	COG3540	Alkaline phosphatase
IYN96_19770	COG2091	lysine biosynthetic process via aminoadipic acid
IYN96_19785	COG0708	Exodeoxyribonuclease III
IYN96_19800	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IYN96_19805	COG3162	membrane
IYN96_19845	COG1414	Transcriptional regulator
IYN96_19855	COG2205	protein histidine kinase activity
IYN96_19865	COG3459	Glycosyltransferase 36 associated
IYN96_19875	COG3265	gluconokinase activity
IYN96_19880	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IYN96_19885	COG3039	Transposase
IYN96_19900	COG0339	signal peptide processing
IYN96_19930	COG0564	pseudouridine synthase activity
IYN96_19945	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
IYN96_19955	COG1181	Belongs to the D-alanine--D-alanine ligase family
IYN96_19965	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IYN96_19970	COG0318	PFAM AMP-dependent synthetase and ligase
IYN96_19975	COG0727	PFAM Uncharacterised protein family (UPF0153)
IYN96_19980	COG0596	Alpha beta hydrolase
IYN96_19985	COG3177	Filamentation induced by cAMP protein fic
IYN96_19990	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IYN96_20005	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
IYN96_20030	COG4191	Histidine kinase
IYN96_20035	COG0028	Belongs to the TPP enzyme family
IYN96_20050	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
IYN96_20055	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IYN96_20100	COG3039	Transposase
IYN96_20110	COG0183	Belongs to the thiolase family
IYN96_20135	COG3039	Transposase
IYN96_20165	COG2032	superoxide dismutase activity
IYN96_20170	COG2032	superoxide dismutase activity
IYN96_20175	COG2204	response regulator
IYN96_20180	COG3852	Histidine kinase
IYN96_20185	COG0004	ammonium transporteR
IYN96_20190	COG0347	Belongs to the P(II) protein family
IYN96_20195	COG0174	glutamine synthetase
IYN96_20200	COG1968	undecaprenyl-diphosphatase activity
IYN96_20245	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IYN96_20255	COG2062	phosphohistidine phosphatase, SixA
IYN96_20260	COG0489	protein tyrosine kinase activity
IYN96_20280	COG1396	sequence-specific DNA binding
IYN96_20285	COG3550	peptidyl-serine autophosphorylation
IYN96_20290	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
IYN96_20295	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IYN96_20310	COG1125	glycine betaine transport
IYN96_20310	COG0517	IMP dehydrogenase activity
IYN96_20325	COG1119	ATPase activity
IYN96_20335	COG1473	amidohydrolase
IYN96_20340	COG1752	Esterase of the alpha-beta hydrolase superfamily
IYN96_20350	COG1522	sequence-specific DNA binding
IYN96_20355	COG3186	Phenylalanine-4-hydroxylase
IYN96_20375	COG1609	Transcriptional regulator
IYN96_20400	COG0366	Alpha amylase catalytic
IYN96_20405	COG0366	Alpha amylase catalytic
IYN96_20415	COG2831	hemolysin activation secretion protein
IYN96_20420	COG3210	domain, Protein
IYN96_20465	COG3135	benzoate transporter
IYN96_20485	COG0676	glucose-6-phosphate 1-epimerase activity
IYN96_20540	COG0302	gtp cyclohydrolase
IYN96_20570	COG0477	Major facilitator Superfamily
IYN96_20580	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IYN96_20630	COG3237	CsbD-like
IYN96_20720	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IYN96_20745	COG1755	Isoprenylcysteine carboxyl methyltransferase
IYN96_20750	COG1304	FMN binding
IYN96_20755	COG3039	Transposase
IYN96_20765	COG4772	TonB-dependent receptor
IYN96_20775	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
IYN96_20800	COG1272	protein, Hemolysin III
IYN96_20805	COG1111	helicase
IYN96_20805	COG1205	dead DEAH box helicase
IYN96_20865	COG0067	glutamate synthase
IYN96_20865	COG0069	glutamate synthase activity
IYN96_20865	COG0070	glutamate synthase
IYN96_20870	COG0493	'glutamate synthase
IYN96_20880	COG0531	amino acid
IYN96_20890	COG1322	Protein conserved in bacteria
IYN96_20900	COG0386	Belongs to the glutathione peroxidase family
IYN96_20905	COG2853	Lipoprotein
IYN96_20920	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
IYN96_20925	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
IYN96_20930	COG1127	ABC transporter
IYN96_20965	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
IYN96_20970	COG1074	ATP-dependent DNA helicase activity
IYN96_20975	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IYN96_21030	COG2826	transposase and inactivated derivatives, IS30 family
IYN96_21050	COG3039	Transposase
IYN96_21060	COG2124	cytochrome p450
IYN96_21065	COG2124	cytochrome p450
IYN96_21070	COG1141	Ferredoxin
IYN96_21075	COG1028	Short-chain dehydrogenase reductase Sdr
IYN96_21080	COG2124	cytochrome p450
IYN96_21085	COG0142	geranyltranstransferase activity
IYN96_21090	COG1657	PFAM Prenyltransferase squalene oxidase
IYN96_21100	COG1304	FMN binding
IYN96_21115	COG0564	pseudouridine synthase activity
IYN96_21140	COG3706	GGDEF domain
IYN96_21150	COG1929	Belongs to the glycerate kinase type-1 family
IYN96_21155	COG2271	Major facilitator Superfamily
IYN96_21175	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
IYN96_21180	COG0861	Integral membrane protein TerC family
IYN96_21190	COG0584	glycerophosphoryl diester phosphodiesterase
IYN96_21200	COG0671	phosphoesterase, PA-phosphatase related
IYN96_21205	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
IYN96_21210	COG0726	polysaccharide deacetylase