locus-tag	class	description
XPE_00030	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
XPE_00035	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
XPE_00040	ENOG4105VIE	preprotein translocase, subunit YajC
XPE_00045	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
XPE_00050	ENOG4107QT7	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
XPE_00100	ENOG4105DM4	PTS System
XPE_00105	ENOG4105DE4	1-phosphofructokinase
XPE_00110	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
XPE_00115	ENOG4108M60	Transcriptional regulator
XPE_00120	ENOG4105BZS	acriflavin resistance protein
XPE_00125	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
XPE_00135	ENOG4105C7I	Dehydrogenase
XPE_00140	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
XPE_00145	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
XPE_00150	ENOG4105BZU	Histidine kinase
XPE_00155	ENOG4106BRA	Membrane
XPE_00175	ENOG4105FCD	Major Facilitator
XPE_00180	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
XPE_00185	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
XPE_00195	ENOG4105CSH	Transporter
XPE_00200	ENOG4105W3S	hemerythrin-like, metal-binding protein
XPE_00205	ENOG4105BZU	Histidine kinase
XPE_00210	ENOG4105CJP	fad dependent oxidoreductase
XPE_00215	ENOG4105CFQ	glutamine synthetase
XPE_00230	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
XPE_00235	ENOG4107RUE	extracellular solute-binding protein family 1
XPE_00255	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
XPE_00265	ENOG4105F38	ABC transporter, permease
XPE_00270	ENOG4105D38	putrescine abc transporter
XPE_00290	ENOG4108JU5	Magnesium and cobalt efflux protein
XPE_00300	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
XPE_00310	ENOG4105C9A	Phoh family
XPE_00315	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
XPE_00330	ENOG4105E4C	Lytic transglycosylase catalytic
XPE_00340	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
XPE_00345	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
XPE_00350	ENOG4105EIX	cytochrome c1
XPE_00355	ENOG4107MKT	Stringent starvation protein a
XPE_00360	ENOG4105KB2	stringent starvation protein b
XPE_00380	ENOG4107QRT	dEAD DEAH box helicase
XPE_00385	ENOG4108VX5	3-methyladenine DNA glycosylase
XPE_00390	ENOG4105C8Q	Methyl-accepting chemotaxis
XPE_00395	ENOG4108V3W	Chemotaxis protein, CheW
XPE_00425	ENOG4105DQE	DNA ligase
XPE_00445	ENOG4105E6M	Sulphatase-modifying factor protein
XPE_00460	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
XPE_00465	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
XPE_00470	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
XPE_00475	ENOG4105K8N	protein family UPF0079, ATPase
XPE_00480	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
XPE_00485	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
XPE_00510	ENOG4105CHR	reductase
XPE_00515	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
XPE_00520	ENOG4105D0M	Protease HtpX homolog
XPE_00530	ENOG4105CBX	hi0933 family
XPE_00535	ENOG4108VWS	Yaeq family
XPE_00540	ENOG4105VEQ	Cold shock protein
XPE_00545	ENOG4108RXX	maleylacetoacetate isomerase
XPE_00555	ENOG4105CNG	UPF0061 protein
XPE_00560	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
XPE_00565	ENOG4105C1J	atp-dependent rna helicase
XPE_00570	ENOG4105C5H	ABC transporter
XPE_00585	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
XPE_00590	ENOG4105ECY	inositol monophosphatase
XPE_00605	ENOG4105BZU	Histidine kinase
XPE_00610	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
XPE_00615	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
XPE_00625	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
XPE_00630	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
XPE_00635	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
XPE_00670	ENOG4107FQ9	ethanolamine ammonia-lyase
XPE_00675	ENOG4105CPD	ethanolamine ammonia-lyase
XPE_00700	ENOG4105CD3	dihydroorotase
XPE_00705	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
XPE_00710	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
XPE_00720	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
XPE_00725	ENOG4105C8N	cysteinyl-tRNA synthetase
XPE_00735	ENOG4105DBV	ornithine carbamoyltransferase
XPE_00740	ENOG4105CDH	Citrulline--aspartate ligase
XPE_00755	ENOG4105CAS	nag kinase
XPE_00765	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
XPE_00770	ENOG4105CH7	arginosuccinase
XPE_00780	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
XPE_00785	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
XPE_00815	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
XPE_00820	ENOG4105C4M	(Ubiquinol oxidase) subunit I
XPE_00825	ENOG4108JJ9	ABC, transporter
XPE_00830	ENOG4108JJ8	(ABC) transporter
XPE_00840	ENOG4105DWV	Homoserine O-trans-acetylase
XPE_00845	ENOG4108M1T	Cytochrome c-type biogenesis protein
XPE_00850	ENOG4105KWW	Biogenesis protein
XPE_00860	ENOG4105DA4	cytochrome c-type biogenesis protein
XPE_00865	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
XPE_00875	ENOG41060IM	Heme exporter protein
XPE_00880	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
XPE_00885	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
XPE_00890	ENOG4105CHM	Aminotransferase
XPE_00910	ENOG4105FE9	pseudouridine synthase
XPE_00915	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
XPE_00920	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
XPE_00925	ENOG4105K9H	YciI-like protein
XPE_00960	ENOG4105DRS	transport system, permease
XPE_00990	ENOG4105DWY	Agmatine deiminase
XPE_01000	ENOG4105YK5	50S ribosomal protein L36
XPE_01005	ENOG4105CAT	Cytidine monophosphate kinase
XPE_01010	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
XPE_01015	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
XPE_01025	ENOG4105CFV	Tetratricopeptide repeat protein
XPE_01030	ENOG4105ESV	Glycosyl transferase, family 4
XPE_01040	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
XPE_01045	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
XPE_01055	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
XPE_01060	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
XPE_01065	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
XPE_01075	ENOG4108R3E	Dna-3-methyladenine glycosylase i
XPE_01090	ENOG410642W	LysR family Transcriptional regulator
XPE_01100	ENOG4105EVH	UPF0753 protein
XPE_01110	ENOG4105DND	Transcriptional regulator
XPE_01120	ENOG4107Z7P	Ferredoxin
XPE_01135	ENOG4105HMI	Membrane
XPE_01140	ENOG4105DUM	transcriptional regulator, lysR family
XPE_01155	ENOG4105WH1	Two component transcriptional regulator luxr family
XPE_01160	ENOG4105ENE	Histidine kinase
XPE_01170	ENOG4105CHJ	isochorismatase hydrolase
XPE_01185	ENOG4107SFI	Major Facilitator superfamily
XPE_01205	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
XPE_01210	ENOG4105KST	dependent repressor
XPE_01215	ENOG4108Z6B	deaminase
XPE_01220	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
XPE_01235	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
XPE_01255	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
XPE_01265	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
XPE_01290	ENOG4105BZM	domain protein
XPE_01295	ENOG4105BZU	Histidine kinase
XPE_01335	ENOG4105N7H	Cytochrome
XPE_01365	ENOG4108UHU	Aldolase
XPE_01370	ENOG4105C01	Dihydroxy-acid dehydratase
XPE_01375	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
XPE_01380	ENOG4105CHC	glucokinase (EC 2.7.1.2)
XPE_01395	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
XPE_01405	ENOG410612Q	succinate dehydrogenase (cytochrome b-556 subunit)
XPE_01430	ENOG410681N	tpr repeat protein
XPE_01440	ENOG4105D60	lipoprotein releasing system transmembrane protein
XPE_01445	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
XPE_01455	ENOG4108EC8	DNA internalization-related competence protein ComEC
XPE_01470	ENOG4105BZ1	(ABC) transporter
XPE_01475	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
XPE_01480	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
XPE_01495	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
XPE_01500	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
XPE_01525	ENOG4107QQG	Dehydrogenase
XPE_01535	ENOG4108V1T	peptidylprolyl cis-trans isomerase
XPE_01545	ENOG4105C72	UPF0176 protein
XPE_01555	ENOG4105C03	ribonuclease
XPE_01560	ENOG4105EI2	Pseudouridine synthase
XPE_01565	ENOG4108NST	exported protein
XPE_01570	ENOG4105DUN	Mediates zinc uptake. May also transport other divalent cations (By similarity)
XPE_01580	ENOG41090A4	Pterin carbinolamine dehydratase
XPE_01585	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
XPE_01595	ENOG4105RJZ	Transcriptional regulator
XPE_01600	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
XPE_01605	ENOG4105BZS	acriflavin resistance protein
XPE_01610	ENOG4108IG5	Transcriptional regulator
XPE_01620	ENOG4105CIR	epoxide hydrolase
XPE_01645	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
XPE_01660	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
XPE_01670	ENOG4105EWI	Short-chain dehydrogenase reductase Sdr
XPE_01700	ENOG41080HT	Transcriptional regulator, arsr family
XPE_01735	ENOG4105WH1	Two component transcriptional regulator luxr family
XPE_01740	ENOG4105ENE	Histidine kinase
XPE_01745	ENOG4108ZXC	Two component transcriptional regulator, luxr family
XPE_01770	ENOG4105CA0	peroxidase
XPE_01800	ENOG4107TPY	serine threonine protein kinase
XPE_01805	ENOG4108ZF3	Phosphatase
XPE_01840	ENOG4105CS6	Rhs element vgr protein
XPE_01865	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
XPE_01890	ENOG4108WC9	type VI secretion system effector, hcp1 family
XPE_01980	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
XPE_01990	ENOG4108ZXC	Two component transcriptional regulator, luxr family
XPE_02015	ENOG4108N8X	transition metal ion binding
XPE_02030	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
XPE_02045	ENOG4108IFG	nitrite reductase, (NAD(P)H)
XPE_02055	ENOG4105I5W	Transporter
XPE_02065	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
XPE_02070	ENOG4105H3G	oxidoreductase
XPE_02090	ENOG41085AN	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
XPE_02095	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
XPE_02105	ENOG4105CGK	Exodeoxyribonuclease III
XPE_02150	ENOG4105D06	uba thif-type nad fad binding protein
XPE_02155	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
XPE_02160	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
XPE_02165	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
XPE_02175	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
XPE_02185	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
XPE_02190	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
XPE_02205	ENOG4105CHU	acetyl-coa acetyltransferase
XPE_02210	ENOG41082MI	Protein CrcB homolog
XPE_02215	ENOG4105D1H	recombination factor protein RarA
XPE_02230	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
XPE_02240	ENOG4105CNU	cell division protein FtsK
XPE_02245	ENOG4105C3M	thioredoxin reductase
XPE_02260	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
XPE_02265	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
XPE_02270	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
XPE_02275	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
XPE_02285	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
XPE_02290	ENOG41075W9	High frequency lysogenization protein HflD homolog
XPE_02310	ENOG4105BZU	Histidine kinase
XPE_02320	ENOG4105BZU	Histidine kinase
XPE_02325	ENOG4105BZU	Histidine kinase
XPE_02345	ENOG4107R88	Chemotaxis protein (CheV)
XPE_02355	ENOG4108ZC9	flagellar basal-body rod protein flgc
XPE_02360	ENOG410822I	Flagellar hook capping protein
XPE_02365	ENOG4105BZE	flagellar hook protein, FlgE
XPE_02370	ENOG4108KPB	Flagellar basal-body rod protein FlgF
XPE_02380	ENOG4105CGA	flagellar basal-body rod protein FlgG
XPE_02385	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
XPE_02390	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
XPE_02395	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
XPE_02405	ENOG4105DTJ	flagellar hook-associated protein
XPE_02415	ENOG4107W9T	flagellar hook-associated
XPE_02420	ENOG4105MQ3	flagellar protein FliS
XPE_02440	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
XPE_02445	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
XPE_02450	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
XPE_02465	ENOG4108P1X	synthase
XPE_02470	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
XPE_02475	ENOG4105CHR	reductase
XPE_02500	ENOG4105C74	pyruvyl transferase
XPE_02505	ENOG4107RGC	Glycosyl transferase, family 2
XPE_02510	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
XPE_02515	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
XPE_02520	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
XPE_02530	ENOG4108JIR	Flagellum-specific ATP synthase
XPE_02550	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
XPE_02555	ENOG4105DD5	Flagellar motor switch protein
XPE_02560	ENOG4105K0P	flagellar biosynthesis protein
XPE_02565	ENOG4105CN7	Flagellar biosynthetic protein FliP
XPE_02575	ENOG4105VS8	Flagellar biosynthetic protein fliq
XPE_02580	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
XPE_02585	ENOG4105BZU	Histidine kinase
XPE_02595	ENOG4105BZU	Histidine kinase
XPE_02600	ENOG4105BZU	Histidine kinase
XPE_02605	ENOG4105D00	flagellar biosynthetic protein flhB
XPE_02610	ENOG4105D7B	Flagellar biosynthesis protein flha
XPE_02615	ENOG4105FZW	flagellar biosynthesis regulator FlhF
XPE_02620	ENOG4107R21	site-determining protein
XPE_02625	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
XPE_02630	ENOG4108VYJ	response regulator receiver protein
XPE_02640	ENOG4105CBS	Chea signal transduction histidine kinase
XPE_02700	ENOG4105CMM	transposase
XPE_02725	ENOG4105E14	MotA TolQ exbB proton channel
XPE_02730	ENOG4105ER2	Ompa motb domain protein
XPE_02735	ENOG4107QJE	Chromosome Partitioning Protein
XPE_02750	ENOG4108VYJ	response regulator receiver protein
XPE_02755	ENOG4105CBS	Chea signal transduction histidine kinase
XPE_02760	ENOG4108W2P	Methyl-accepting chemotaxis
XPE_02765	ENOG4105C8Q	Methyl-accepting chemotaxis
XPE_02775	ENOG4105C8Q	Methyl-accepting chemotaxis
XPE_02780	ENOG4105C8Q	Methyl-accepting chemotaxis
XPE_02790	ENOG4105C8Q	Methyl-accepting chemotaxis
XPE_02795	ENOG4105C8Q	Methyl-accepting chemotaxis
XPE_02800	ENOG4105C8Q	Methyl-accepting chemotaxis
XPE_02805	ENOG4105C8Q	Methyl-accepting chemotaxis
XPE_02815	ENOG4105C8Q	Methyl-accepting chemotaxis
XPE_02825	ENOG4105C8Q	Methyl-accepting chemotaxis
XPE_02830	ENOG4105C8Q	Methyl-accepting chemotaxis
XPE_02835	ENOG4105C8Q	Methyl-accepting chemotaxis
XPE_02840	ENOG4105C8Q	Methyl-accepting chemotaxis
XPE_02855	ENOG4108V3W	Chemotaxis protein, CheW
XPE_02865	ENOG4105C8Q	Methyl-accepting chemotaxis
XPE_02870	ENOG4105BZU	Histidine kinase
XPE_02875	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
XPE_02880	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
XPE_02885	ENOG4105BZU	Histidine kinase
XPE_02890	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
XPE_02895	ENOG4107QIJ	Aconitate hydratase 2
XPE_02910	ENOG4107QM5	aconitate hydratase
XPE_02920	ENOG4105CEY	Amp-dependent synthetase and ligase
XPE_02925	ENOG4105E39	Enoyl-CoA hydratase
XPE_02930	ENOG4105BZU	Histidine kinase
XPE_02935	ENOG4105BZU	Histidine kinase
XPE_02940	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
XPE_02945	ENOG4105CRK	lysyL-tRNA synthetase
XPE_02950	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
XPE_02955	ENOG4105DY9	regulatoR
XPE_02965	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
XPE_02975	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
XPE_02980	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
XPE_02990	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
XPE_02995	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
XPE_03005	ENOG4108RPX	mosc domain containing protein
XPE_03010	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
XPE_03025	ENOG4105CE1	Ferrous iron transport protein b
XPE_03045	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
XPE_03055	ENOG4105FUQ	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
XPE_03075	ENOG4105CQB	FAD linked oxidase domain protein
XPE_03080	ENOG4108JQ1	Dehydrogenase
XPE_03090	ENOG4105CUB	amino acid
XPE_03095	ENOG4105CUB	amino acid
XPE_03100	ENOG4107QY0	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity)
XPE_03105	ENOG4108CAF	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity)
XPE_03110	ENOG4106YVY	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) (By similarity)
XPE_03125	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
XPE_03130	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
XPE_03135	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
XPE_03140	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
XPE_03145	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
XPE_03150	ENOG4105CIH	Imidazole acetol-phosphate transaminase
XPE_03155	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
XPE_03160	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
XPE_03170	ENOG4105CUT	histidyl-tRNA synthetase
XPE_03175	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
XPE_03185	ENOG4105D98	threonine synthase
XPE_03200	ENOG4105CFH	Aspartokinase
XPE_03205	ENOG4105KAV	tspo and mbr like protein
XPE_03265	ENOG4105C26	Dehydrogenase
XPE_03285	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
XPE_03290	ENOG4105D4A	Cell wall formation (By similarity)
XPE_03310	ENOG410841Q	phosphoesterase PA-phosphatase related protein
XPE_03315	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
XPE_03330	ENOG4108UYB	regulatoR
XPE_03335	ENOG4105KU2	hydrolase family 5
XPE_03380	ENOG4107QP8	phosphohexose isomerase
XPE_03385	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
XPE_03390	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
XPE_03395	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
XPE_03400	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
XPE_03405	ENOG4105DJ0	Poly(A) Polymerase
XPE_03415	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
XPE_03420	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
XPE_03440	ENOG4105C93	Xylose Isomerase
XPE_03445	ENOG4105CMG	Carbohydrate kinase
XPE_03495	ENOG4108RTU	Aldolase
XPE_03500	ENOG4105CXK	mandelate racemase muconate lactonizing
XPE_03510	ENOG4105EI3	2-dehydro-3-deoxygalactonokinase EC 2.7.1.58
XPE_03515	ENOG4108Z4U	Ferredoxin
XPE_03525	ENOG4107TUS	Dihydrodipicolinate synthase
XPE_03540	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
XPE_03545	ENOG4108IAB	Phoh family
XPE_03585	ENOG4105CWB	LysR family transcriptional Regulator
XPE_03595	ENOG4107SDU	Methyl-accepting chemotaxis
XPE_03610	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
XPE_03615	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
XPE_03620	ENOG4105Y3E	Modulates RecA activity (By similarity)
XPE_03630	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
XPE_03635	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
XPE_03640	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
XPE_03645	ENOG4107TH8	cina domain protein
XPE_03650	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
XPE_03655	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
XPE_03660	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
XPE_03665	ENOG4105EEI	dihydropteroate synthase
XPE_03670	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
XPE_03675	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
XPE_03680	ENOG4105HBR	Rna-binding protein
XPE_03690	ENOG4108K5P	(LipO)protein
XPE_03695	ENOG4108UM1	dedA family
XPE_03700	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
XPE_03705	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
XPE_03710	ENOG4108DG9	Smr protein MutS2
XPE_03715	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
XPE_03720	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
XPE_03725	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
XPE_03730	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
XPE_03735	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
XPE_03745	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
XPE_03750	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
XPE_03760	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
XPE_03775	ENOG4105CJ3	phosphate transporter
XPE_03805	ENOG4105DEN	Luciferase family
XPE_03810	ENOG4105C54	Major Facilitator superfamily
XPE_03815	ENOG4105BZ1	(ABC) transporter
XPE_03820	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
XPE_03840	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
XPE_03850	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
XPE_03880	ENOG4105EGZ	biosynthesis protein
XPE_03935	ENOG4105EMN	RNA polymerase sigma factor
XPE_03950	ENOG41060IM	Heme exporter protein
XPE_03960	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
XPE_03965	ENOG4105DA4	cytochrome c-type biogenesis protein
XPE_03970	ENOG4107QX9	Thiol disulfide interChange protein
XPE_03975	ENOG4105KWW	Biogenesis protein
XPE_04000	ENOG4105BZU	Histidine kinase
XPE_04020	ENOG4105C8Q	Methyl-accepting chemotaxis
XPE_04035	ENOG4105CC0	LysR family Transcriptional regulator
XPE_04040	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
XPE_04045	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
XPE_04060	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
XPE_04070	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
XPE_04075	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
XPE_04080	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
XPE_04120	ENOG4105CI2	imidazolone-5-propionate hydrolase
XPE_04125	ENOG4105C84	Histidine ammonia-lyase
XPE_04135	ENOG4105CGP	Urocanate hydratase
XPE_04145	ENOG4105DZG	Dehydrogenase
XPE_04150	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
XPE_04155	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
XPE_04170	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
XPE_04175	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
XPE_04180	ENOG4105CIH	Imidazole acetol-phosphate transaminase
XPE_04190	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
XPE_04200	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
XPE_04205	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
XPE_04210	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
XPE_04215	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
XPE_04225	ENOG4105C5S	asparaginyl-tRNA synthetase
XPE_04250	ENOG4105WH1	Two component transcriptional regulator luxr family
XPE_04295	ENOG41077A9	carbonic anhydrase
XPE_04300	ENOG4105C3W	Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate (By similarity)
XPE_04310	ENOG4105CKY	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively (By similarity)
XPE_04315	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
XPE_04325	ENOG4105CJB	Exodeoxyribonuclease I
XPE_04335	ENOG4105CPC	Aldo Keto reductase
XPE_04350	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
XPE_04355	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
XPE_04395	ENOG4105KHC	sulfurtransferase
XPE_04400	ENOG4105P8F	nudix hydrolase
XPE_04405	ENOG4108V1T	peptidylprolyl cis-trans isomerase
XPE_04410	ENOG4105E39	Enoyl-CoA hydratase
XPE_04420	ENOG4105CSM	endonuclease III
XPE_04425	ENOG4105CHH	sulfate transporter
XPE_04430	ENOG4107B2H	carbonic anhydrase
XPE_04450	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
XPE_04455	ENOG4105C8U	phosphate abc transporter
XPE_04460	ENOG4105E2Z	phosphate ABC transporter (Permease
XPE_04465	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
XPE_04470	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
XPE_04480	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
XPE_04485	ENOG4105BZU	Histidine kinase
XPE_04495	ENOG4105C2N	RNA methyltransferase TrmH family group 3
XPE_04505	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
XPE_04535	ENOG4105C1G	acyl-Coa dehydrogenase
XPE_04545	ENOG4105C3R	Methionine synthase
XPE_04550	ENOG4105C3R	Methionine synthase
XPE_04560	ENOG4105D7K	pfkb domain protein
XPE_04570	ENOG4105ETE	Transcriptional regulator (LacI family
XPE_04585	ENOG41069P5	Protein slyX homolog
XPE_04590	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
XPE_04595	ENOG4108V1T	peptidylprolyl cis-trans isomerase
XPE_04610	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
XPE_04615	ENOG4105CZV	ABC transporter
XPE_04645	ENOG4105C37	(CBS) domain
XPE_04655	ENOG4107QTF	adenylosuccinate lyase
XPE_04665	ENOG4105EZE	Cupin 4 family protein
XPE_04675	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
XPE_04680	ENOG4105C7S	Dehydrogenase
XPE_04690	ENOG4108URH	decarboxylase
XPE_04700	ENOG4105BZ1	(ABC) transporter
XPE_04705	ENOG4105C5Q	Transcriptional regulator
XPE_04740	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
XPE_04745	ENOG4105CFG	Acts as a chaperone (By similarity)
XPE_04750	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
XPE_04755	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
XPE_04760	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
XPE_04765	ENOG41090R7	Ferric uptake
XPE_04770	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
XPE_04780	ENOG4108Z1B	Cyclase dehydrase
XPE_04785	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
XPE_04820	ENOG4106TD9	Diguanylate cyclase
XPE_04830	ENOG4105BZU	Histidine kinase
XPE_04865	ENOG4105CR8	Transcriptional regulator
XPE_04870	ENOG4105CDV	Ompa motb domain protein
XPE_04880	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
XPE_04885	ENOG4105CDU	Replicative dna helicase
XPE_04895	ENOG4105CAQ	asparagine synthetase
XPE_04905	ENOG4108K3A	Glutathione S-transferase
XPE_04915	ENOG4105C1G	acyl-Coa dehydrogenase
XPE_04930	ENOG4105F8V	Hydrolase, tatD family
XPE_04935	ENOG4105CUZ	uba thif-type nad fad binding protein
XPE_04950	ENOG4105VEQ	Cold shock protein
XPE_04960	ENOG4105HDD	phospholipase
XPE_04980	ENOG4107GFK	fumarate
XPE_04990	ENOG4105DP0	ferredoxin-NADP reductase
XPE_04995	ENOG4108V06	Glutathione peroxidase
XPE_05000	ENOG4105DGW	oligopeptidase A
XPE_05030	ENOG4105DUX	Transporter
XPE_05040	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
XPE_05060	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
XPE_05065	ENOG4105CW7	secretion protein, HlyD family
XPE_05085	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
XPE_05090	ENOG4105FQ6	thiopurine methyltransferase
XPE_05095	ENOG4108UWD	Iron-storage protein
XPE_05105	ENOG4108ESX	Receptor
XPE_05115	ENOG4105CAQ	asparagine synthetase
XPE_05120	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
XPE_05125	ENOG4105KUZ	arsenate reductase
XPE_05135	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
XPE_05140	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
XPE_05175	ENOG4105CE9	30S ribosomal protein S2
XPE_05180	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
XPE_05185	ENOG4105BZU	Histidine kinase
XPE_05190	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
XPE_05195	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
XPE_05200	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
XPE_05205	ENOG4105KNE	Phosphatidate cytidylyltransferase
XPE_05210	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
XPE_05215	ENOG4105DZP	Membrane-associated zinc metalloprotease
XPE_05220	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XPE_05230	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
XPE_05235	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
XPE_05240	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
XPE_05245	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
XPE_05260	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
XPE_05275	ENOG4108YXA	Membrane
XPE_05325	ENOG4107QK5	Homocysteine s-methyltransferase
XPE_05330	ENOG4108IQI	permease
XPE_05345	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
XPE_05365	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
XPE_05375	ENOG4108R3D	Electron transport complex
XPE_05395	ENOG4105K6V	RNA polymerase
XPE_05420	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
XPE_05435	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
XPE_05440	ENOG4105M4H	endoribonuclease L-psp
XPE_05485	ENOG4105F27	Major Facilitator
XPE_05490	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
XPE_05495	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
XPE_05505	ENOG4108YZY	peptidylprolyl cis-trans isomerase
XPE_05510	ENOG4105DFF	Rod shape-determining protein mreb
XPE_05525	ENOG4105KSC	Transcriptional regulator, TraR DksA family
XPE_05540	ENOG4108VKG	metal-dependent hydrolase
XPE_05565	ENOG4105CHU	acetyl-coa acetyltransferase
XPE_05580	ENOG4105BZU	Histidine kinase
XPE_05600	ENOG4107T0X	DNA ligase
XPE_05610	ENOG4107T0X	DNA ligase
XPE_05615	ENOG4107QRT	dEAD DEAH box helicase
XPE_05625	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
XPE_05630	ENOG4105VEQ	Cold shock protein
XPE_05635	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
XPE_05640	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
XPE_05645	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
XPE_05650	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
XPE_05655	ENOG4105EWK	phytoene
XPE_05660	ENOG4107ZXU	DSBA oxidoreductase
XPE_05665	ENOG41080ZE	Adenylate cyclase
XPE_05670	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
XPE_05685	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
XPE_05690	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
XPE_05695	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
XPE_05705	ENOG4105C3F	Signal peptidase i
XPE_05710	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
XPE_05715	ENOG4105C0H	protease
XPE_05725	ENOG4105EMN	RNA polymerase sigma factor
XPE_05730	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
XPE_05740	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
XPE_05745	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
XPE_05750	ENOG4105E39	Enoyl-CoA hydratase
XPE_05755	ENOG4105C1G	acyl-Coa dehydrogenase
XPE_05760	ENOG4105C26	Dehydrogenase
XPE_05775	ENOG4106FKC	arabinogalactan endo-1,4-beta-galactosidase
XPE_05780	ENOG4105CNT	hydrolase family 2
XPE_05810	ENOG4107791	aminotransferase class V
XPE_05830	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
XPE_05840	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
XPE_05845	ENOG4105VEJ	Heat shock protein
XPE_05860	ENOG4107QJQ	Mate efflux family protein
XPE_05865	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
XPE_05870	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
XPE_05875	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
XPE_05880	ENOG4105K5M	30s ribosomal protein S16
XPE_05890	ENOG4107QWG	2-Nitropropane dioxygenase
XPE_05895	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
XPE_05900	ENOG4105CRE	cytochrome C
XPE_05905	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
XPE_05910	ENOG4105CZZ	Alpha-N-arabinofuranosidase (EC 3.2.1.55)
XPE_05920	ENOG4105CQZ	Histidine kinase
XPE_05925	ENOG4105BZU	Histidine kinase
XPE_05930	ENOG4105BZU	Histidine kinase
XPE_05935	ENOG4107Z5C	methylesterase
XPE_05940	ENOG4105C08	Histidine kinase
XPE_05945	ENOG4105KCV	RNA signal recognition particle 4.5S RNA
XPE_05970	ENOG4105BZU	Histidine kinase
XPE_05980	ENOG4105QD0	anti-sigma regulatory factor serine threonine protein kinase
XPE_05985	ENOG4105FUA	antagonist
XPE_05990	ENOG4107MMM	Anti-sigma-factor antagonist
XPE_06000	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
XPE_06015	ENOG4105KAF	membrAne
XPE_06020	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
XPE_06030	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
XPE_06035	ENOG4105CCU	oxidase (Subunit III)
XPE_06040	ENOG4105BZ9	Cytochrome C oxidase, subunit I
XPE_06055	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
XPE_06060	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
XPE_06065	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
XPE_06070	ENOG4105DTN	riboflavin biosynthesis protein ribF
XPE_06075	ENOG4105CJR	Integral membrane protein (MviN
XPE_06080	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
XPE_06085	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
XPE_06090	ENOG4105K46	50S ribosomal protein l27
XPE_06095	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
XPE_06100	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
XPE_06105	ENOG4108TGP	Thioesterase superfamily protein
XPE_06115	ENOG4105UPE	Enoyl-CoA hydratase
XPE_06120	ENOG4105C29	acyl-CoA thioesterase
XPE_06130	ENOG4105GFR	rna polymerase sigma factor
XPE_06145	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
XPE_06165	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
XPE_06205	ENOG4105WH1	Two component transcriptional regulator luxr family
XPE_06210	ENOG4105BZU	Histidine kinase
XPE_06225	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
XPE_06230	ENOG4107QMS	site-determining protein
XPE_06235	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
XPE_06245	ENOG4105DHQ	Histidine kinase
XPE_06250	ENOG4105ETX	regulatoR
XPE_06265	ENOG4105DIJ	Phosphoethanolamine transferase
XPE_06285	ENOG4105C2C	drug resistance transporter, Bcr CflA
XPE_06290	ENOG4108JJA	ABC, transporter
XPE_06310	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
XPE_06315	ENOG4105EBR	Carboxylesterase
XPE_06320	ENOG4105CV8	reductase
XPE_06350	ENOG4106AXJ	AraC family transcriptional regulator
XPE_06365	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
XPE_06380	ENOG4105EPD	Oligopeptide transporter, Opt family
XPE_06400	ENOG4105C0B	DNA polymerase III (alpha subunit)
XPE_06415	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
XPE_06450	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
XPE_06455	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
XPE_06460	ENOG4105C7W	Xanthine dehydrogenase
XPE_06485	ENOG4105C3M	thioredoxin reductase
XPE_06495	ENOG4107JEE	Short-chain dehydrogenase reductase Sdr
XPE_06505	ENOG4105CWX	Alpha-1,2-mannosidase
XPE_06510	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
XPE_06515	ENOG4105BZP	glycoside hydrolase 15-related
XPE_06525	ENOG4107Z4K	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
XPE_06530	ENOG4105CVJ	phosphoglycerate mutase
XPE_06570	ENOG4107SCJ	type I restriction enzyme EcoKI subunit R
XPE_06585	ENOG4107XZC	Restriction modification system DNA (Specificity
XPE_06600	ENOG4108XFH	Transcriptional regulator
XPE_06605	ENOG4105F6U	Short-chain dehydrogenase reductase Sdr
XPE_06615	ENOG4105CD8	aminopeptidase N
XPE_06620	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
XPE_06630	ENOG4105EPW	hflc protein
XPE_06635	ENOG4107QJR	hflk protein
XPE_06640	ENOG4105M3Z	response regulator
XPE_06665	ENOG4108JQB	penicillin-binding protein 1C
XPE_06685	ENOG4105DN3	alpha-2-macroglobulin domain protein
XPE_06705	ENOG4105C7F	AcnD-accessory protein PrpF
XPE_06715	ENOG4108I0Z	Aconitate hydratase
XPE_06720	ENOG4105BZN	citrate synthase
XPE_06725	ENOG4105CR4	methylisocitrate lyase
XPE_06730	ENOG4108JU7	Transcriptional regulator
XPE_06755	ENOG4107QRG	dna polymerase iii
XPE_06760	ENOG4105HHA	aminodeoxychorismate lyase
XPE_06770	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
XPE_06775	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
XPE_06780	ENOG4105CHR	reductase
XPE_06785	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
XPE_06795	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
XPE_06800	ENOG4105VGS	50s ribosomal protein l32
XPE_06805	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
XPE_06810	ENOG4108UHJ	MAF-like protein
XPE_06825	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
XPE_06835	ENOG4105F8C	transglutaminase domain-containing protein
XPE_06845	ENOG4105K59	histidine triad (HIT) protein
XPE_06850	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
XPE_06855	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
XPE_06860	ENOG4107QMP	dna polymerase iii subunits gamma and tau
XPE_06880	ENOG4105R48	this blockage is overcome by subsequent expression of antitoxin HigA. Overexpression causes cleavage of a number of mRNAs in a translation-dependent fashion, suggesting this is an mRNA interferase
XPE_06925	ENOG4105W5Q	DNA repair protein (RadC
XPE_07010	ENOG4108ZAF	Molybdopterin
XPE_07015	ENOG4105M00	molybdopterin converting factor, subunit 1
XPE_07020	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
XPE_07030	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
XPE_07035	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
XPE_07040	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
XPE_07045	ENOG4105DKP	glycosyl transferase, family 9
XPE_07105	ENOG4108ZF3	Phosphatase
XPE_07110	ENOG4107RZZ	dna polymerase iii epsilon subunit
XPE_07115	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
XPE_07125	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
XPE_07135	ENOG4105EIN	peptidylprolyl cis-trans isomerase
XPE_07165	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
XPE_07170	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
XPE_07175	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
XPE_07185	ENOG4105BZU	Histidine kinase
XPE_07215	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
XPE_07225	ENOG4105VW4	glutaredoxin 3
XPE_07230	ENOG4105ERG	peptidase m48, ste24p
XPE_07235	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
XPE_07240	ENOG4105BZU	Histidine kinase
XPE_07245	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
XPE_07250	ENOG4105C9X	ppx gppa phosphatase
XPE_07255	ENOG4105BZF	Glycosyl transferase (Group 1
XPE_07260	ENOG4105EYK	Phosphatidylglycerophosphatase B
XPE_07265	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
XPE_07275	ENOG4108YP4	Metalloprotease, specifically cleaves on the N-terminal side of aspartyl, glutamyl and cysteic acid residues (By similarity)
XPE_07280	ENOG4105ED9	Protein of unknown function (DUF455)
XPE_07290	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
XPE_07305	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
XPE_07310	ENOG4105CVJ	phosphoglycerate mutase
XPE_07320	ENOG4105HSS	phospholipase C
XPE_07330	ENOG4105CPQ	Dehydrogenase
XPE_07345	ENOG4108IJ6	ABC transporter
XPE_07355	ENOG4108I5D	sulfate abc transporter
XPE_07360	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
XPE_07365	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
XPE_07375	ENOG4108R99	pseudouridine synthase
XPE_07385	ENOG4105F37	PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6
XPE_07390	ENOG4105CIS	alcohol dehydrogenase
XPE_07395	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
XPE_07415	ENOG4108K3A	Glutathione S-transferase
XPE_07420	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
XPE_07425	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
XPE_07440	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
XPE_07450	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
XPE_07470	ENOG41080I0	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
XPE_07475	ENOG4108ZT0	50S ribosomal protein l17
XPE_07480	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
XPE_07485	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
XPE_07490	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
XPE_07495	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
XPE_07500	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
XPE_07505	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
XPE_07515	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
XPE_07520	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
XPE_07525	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
XPE_07530	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
XPE_07535	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
XPE_07540	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
XPE_07545	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
XPE_07550	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
XPE_07555	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
XPE_07565	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
XPE_07570	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
XPE_07575	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
XPE_07580	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
XPE_07585	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
XPE_07590	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
XPE_07595	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
XPE_07600	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
XPE_07605	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
XPE_07620	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
XPE_07625	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
XPE_07630	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
XPE_07635	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
XPE_07640	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
XPE_07645	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
XPE_07650	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
XPE_07655	ENOG4108VZM	50s ribosomal protein L10
XPE_07660	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
XPE_07665	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
XPE_07670	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
XPE_07675	ENOG4105PM1	preprotein translocase subunit SecE
XPE_07685	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
XPE_07705	ENOG4105C3G	gtp-binding protein
XPE_07710	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
XPE_07715	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
XPE_07720	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
XPE_07730	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
XPE_07735	ENOG4105QVB	outer membrane lipoprotein LolB
XPE_07740	ENOG4105DJQ	tetratricopeptide tpr_2 repeat protein
XPE_07745	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
XPE_07750	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
XPE_07765	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
XPE_07770	ENOG4105CSR	polyphosphate kinase 2
XPE_07785	ENOG4107QX9	Thiol disulfide interChange protein
XPE_07790	ENOG4107S2Z	UPF0761 membrane protein
XPE_07795	ENOG4105CS1	NAD(P)H quinone oxidoreductase
XPE_07815	ENOG4108Z66	YbaK ebsC protein
XPE_07820	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
XPE_07830	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
XPE_07835	ENOG4105CM2	brancheD-chain amino acid aminotransferase
XPE_07850	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
XPE_07855	ENOG4105W8H	transhydrogenase (subunit alpha
XPE_07875	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
XPE_07890	ENOG4105C2M	dna polymerase I
XPE_07910	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
XPE_07925	ENOG4105C5Q	Transcriptional regulator
XPE_07935	ENOG4105NXH	GreA GreB family elongation factor
XPE_07940	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
XPE_07950	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
XPE_07960	ENOG4105WH1	Two component transcriptional regulator luxr family
XPE_07965	ENOG4105BZU	Histidine kinase
XPE_07970	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
XPE_07985	ENOG4105CX6	glutaminyL-tRNA synthetase
XPE_07995	ENOG4105DXC	membrane
XPE_08020	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
XPE_08050	ENOG4108D7R	p-hydroxycinnamoyl CoA hydratase lyase
XPE_08060	ENOG4105CEY	Amp-dependent synthetase and ligase
XPE_08065	ENOG4105DDW	LysR family Transcriptional regulator
XPE_08100	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
XPE_08105	ENOG4105D0A	hydroxylase
XPE_08120	ENOG4108WBT	adenosyltransferase
XPE_08130	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
XPE_08135	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
XPE_08140	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
XPE_08145	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
XPE_08150	ENOG4105NWN	ApaG protein
XPE_08155	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
XPE_08170	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
XPE_08175	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
XPE_08195	ENOG41080IJ	Diacylglycerol kinase
XPE_08205	ENOG4105DHQ	Histidine kinase
XPE_08210	ENOG4105ETX	regulatoR
XPE_08215	ENOG4108UJV	acyl-CoA thioesterase i
XPE_08220	ENOG4108I0Y	(ABC) transporter
XPE_08230	ENOG4105E2B	Taurine dioxygenase
XPE_08245	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
XPE_08265	ENOG4105D05	Receptor
XPE_08275	ENOG4105CPC	Aldo Keto reductase
XPE_08285	ENOG4105D9N	nucleoside
XPE_08290	ENOG4108RVA	ribokinase
XPE_08300	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
XPE_08305	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
XPE_08315	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
XPE_08320	ENOG4105D6F	Phosphatase
XPE_08335	ENOG4105UYK	outer membrane protein a
XPE_08355	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
XPE_08365	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
XPE_08370	ENOG4105DXX	methyltransferase
XPE_08435	ENOG4105SYT	Methylenetetrahydrofolate reductase
XPE_08445	ENOG4105M6F	mutator MutT protein
XPE_08450	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
XPE_08455	ENOG4105DR5	peptidase
XPE_08465	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
XPE_08470	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
XPE_08475	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
XPE_08480	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
XPE_08485	ENOG4105CPF	Cell wall formation (By similarity)
XPE_08490	ENOG4105DFU	Cell wall formation (By similarity)
XPE_08495	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
XPE_08505	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
XPE_08510	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
XPE_08515	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
XPE_08520	ENOG4105CJN	penicillin-binding protein
XPE_08525	ENOG4106932	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
XPE_08530	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
XPE_08535	ENOG4108V6E	Cell division protein mraZ
XPE_08570	ENOG41082RQ	UPF0102 protein
XPE_08575	ENOG4105S2T	inner membrane protein YbcI
XPE_08580	ENOG4105CQB	FAD linked oxidase domain protein
XPE_08590	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
XPE_08595	ENOG4105C08	Histidine kinase
XPE_08605	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
XPE_08610	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
XPE_08640	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
XPE_08645	ENOG4107YIM	Involved in the transcription termination process (By similarity)
XPE_08650	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
XPE_08655	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
XPE_08670	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
XPE_08680	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
XPE_08685	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
XPE_08695	ENOG4105C5H	ABC transporter
XPE_08705	ENOG4105C4W	S-formylglutathione hydrolase
XPE_08710	ENOG4108QBQ	Catalyzes the condensation of formaldehyde and glutathione to S-hydroxymethylglutathione (By similarity)
XPE_08735	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
XPE_08740	ENOG4105JJR	Histidine kinase
XPE_08750	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
XPE_08755	ENOG4106RE7	Cytochrome
XPE_08780	ENOG4105C94	Transporter
XPE_08785	ENOG4105C26	Dehydrogenase
XPE_08790	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
XPE_08795	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
XPE_08810	ENOG4105CE4	GlcNAc 6-P deacetylase
XPE_08815	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
XPE_08820	ENOG4105ETE	Transcriptional regulator (LacI family
XPE_08830	ENOG4105FDP	GntR family transcriptional regulator
XPE_08850	ENOG4108RTD	type II secretion system protein K
XPE_08860	ENOG4105X5Z	General secretion pathway protein I
XPE_08865	ENOG4105VWV	general secretion pathway protein h
XPE_08870	ENOG4108VAU	general secretion pathway protein G
XPE_08875	ENOG4105D7Q	type ii secretion system
XPE_08880	ENOG4107QHF	type ii secretion system protein e
XPE_08885	ENOG4105GVR	general secretion pathway protein D
XPE_08925	ENOG4105CHR	reductase
XPE_08935	ENOG4105BZU	Histidine kinase
XPE_08945	ENOG4105BZU	Histidine kinase
XPE_08950	ENOG4105W4M	Transport-associated protein
XPE_08955	ENOG4105D9R	oxidoreductase
XPE_08960	ENOG4108J5G	6-phosphogluconate dehydrogenase
XPE_09005	ENOG4105EGI	Transcriptional regulator
XPE_09015	ENOG4105CN1	protease
XPE_09020	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
XPE_09025	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
XPE_09040	ENOG4105DZ1	carboxypeptidase
XPE_09050	ENOG4105K6T	rare lipoprotein A
XPE_09055	ENOG4105CVE	Lytic murein transglycosylase
XPE_09070	ENOG4105CNI	cell division protein FtsW
XPE_09085	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
XPE_09090	ENOG4105DFF	Rod shape-determining protein mreb
XPE_09100	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
XPE_09130	ENOG4105DZG	Dehydrogenase
XPE_09150	ENOG4105CD8	aminopeptidase N
XPE_09155	ENOG4105BZU	Histidine kinase
XPE_09185	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
XPE_09190	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
XPE_09195	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
XPE_09205	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
XPE_09215	ENOG4105WD1	Membrane
XPE_09270	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
XPE_09275	ENOG4108NEV	two component transcriptional regulator, LytTR family
XPE_09280	ENOG4108HRK	Histidine kinase
XPE_09290	ENOG4105C3A	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity)
XPE_09305	ENOG4105BZU	Histidine kinase
XPE_09310	ENOG4105CHH	sulfate transporter
XPE_09315	ENOG4106R7G	Glycoside hydrolase family 5
XPE_09320	ENOG4105C8Q	Methyl-accepting chemotaxis
XPE_09325	ENOG4105BZU	Histidine kinase
XPE_09355	ENOG4105E53	ec 3.2.1.28
XPE_09370	ENOG4105D7N	magnesium and cobalt transport protein CorA
XPE_09380	ENOG4105C85	amino acid
XPE_09395	ENOG4105F87	Dehydratase
XPE_09400	ENOG4105DFI	Membrane
XPE_09425	ENOG4108Z40	Transcriptional regulator
XPE_09430	ENOG4105BZU	Histidine kinase
XPE_09435	ENOG4107QS8	(LipO)protein
XPE_09480	ENOG4105CHF	Glutathione S-transferase
XPE_09490	ENOG4105PDP	Short chain dehydrogenase
XPE_09550	ENOG4105CMM	transposase
XPE_09650	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
XPE_09685	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
XPE_09690	ENOG4105DRR	Transcriptional regulator, GntR family
XPE_09700	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
XPE_09705	ENOG4108K6F	triphosphoribosyl-dephospho-CoA synthase
XPE_09710	ENOG41065ZS	Transfers 2'-(5-triphosphoribosyl)-3'-dephosphocoenzyme- A to the apo- acyl-carrier-protein of the malonate decarboxylase to yield holo- acyl-carrier-protein (By similarity)
XPE_09725	ENOG4105WSE	Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism (By similarity)
XPE_09750	ENOG4108YYC	ycei family
XPE_09755	ENOG4108RDT	NADH dehydrogenase NAD(P)H nitroreductase)
XPE_09785	ENOG4105EX9	Membrane
XPE_09790	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
XPE_09815	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
XPE_09830	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
XPE_09835	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
XPE_09845	ENOG4108K8S	endonuclease I
XPE_09855	ENOG4105VF7	tolerance protein
XPE_09860	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
XPE_09865	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
XPE_09870	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
XPE_09880	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
XPE_09900	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
XPE_09925	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
XPE_09930	ENOG4108HPI	phosphatidate Cytidylyltransferase
XPE_09955	ENOG41077RS	Phosphatase
XPE_09960	ENOG4105E8V	Alpha Beta Hydrolase Fold protein
XPE_09965	ENOG4108UMZ	Cdp-alcohol phosphatidyltransferase
XPE_09970	ENOG4105DC1	bifunctional purine biosynthesis protein purh
XPE_09980	ENOG4105C12	Phosphoribosylglycinamide synthetase
XPE_09985	ENOG4105EM2	membrane
XPE_10015	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
XPE_10035	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
XPE_10060	ENOG4105BZU	Histidine kinase
XPE_10065	ENOG4108UQY	Iron-storage protein
XPE_10075	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
XPE_10090	ENOG4108UJD	30S ribosomal protein S9
XPE_10095	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
XPE_10100	ENOG4108S0N	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol (By similarity)
XPE_10110	ENOG4105FDS	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
XPE_10115	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
XPE_10125	ENOG4105DK0	Indole-3-glycerol phosphate synthase
XPE_10130	ENOG4108I0Q	anthranilate phosphoribosyltransferase
XPE_10140	ENOG4105DDQ	anthranilate synthase
XPE_10155	ENOG4105CRQ	synthase (Component I)
XPE_10160	ENOG4107TE5	Lipid kinase
XPE_10165	ENOG4105KD7	acetyltransferase
XPE_10175	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
XPE_10180	ENOG4105C8V	SAICAR synthetase
XPE_10200	ENOG4105NVB	glycoside hydrolase, family 19
XPE_10220	ENOG4105D65	subunit l
XPE_10225	ENOG4108ZE9	Monovalent cation H antiporter subunit C
XPE_10230	ENOG4107R4Z	monovalent cation h antiporter subunit d
XPE_10240	ENOG4105W4C	monovalent cation H antiporter subunit F
XPE_10245	ENOG4105KJM	monovalent cation h antiporter subunit g
XPE_10260	ENOG4105F1J	Homogentisate 1,2-dioxygenase
XPE_10265	ENOG4105WDY	DNA (cytosine-5-)-methyltransferase
XPE_10270	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
XPE_10285	ENOG4105DUX	Transporter
XPE_10290	ENOG4105HJ8	Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity)
XPE_10300	ENOG4107RUY	(E1 component), alpha subunit
XPE_10305	ENOG4105CPP	Dehydrogenase, E1 component
XPE_10315	ENOG4105C7S	Dehydrogenase
XPE_10330	ENOG4105C1J	atp-dependent rna helicase
XPE_10345	ENOG4105CHR	reductase
XPE_10350	ENOG4105BZS	acriflavin resistance protein
XPE_10385	ENOG4107ZQV	short-chain dehydrogenase reductase
XPE_10390	ENOG4105K4T	epimerase
XPE_10415	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
XPE_10420	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
XPE_10425	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
XPE_10430	ENOG4105BZU	Histidine kinase
XPE_10435	ENOG4105CKW	Inner membrane protein yedI
XPE_10455	ENOG4107RES	phosphoglycerol transferase I
XPE_10460	ENOG4105EGS	Mechanosensitive ion channel
XPE_10480	ENOG4105FTC	Lytic transglycosylase catalytic
XPE_10515	ENOG4105K44	type iii secretion
XPE_10520	ENOG4108TN6	type iii secretion
XPE_10530	ENOG4108JIR	Flagellum-specific ATP synthase
XPE_10545	ENOG4107Y59	type iii secretion
XPE_10565	ENOG4108HR8	type iii secretion
XPE_10585	ENOG4105VS8	Flagellar biosynthetic protein fliq
XPE_10640	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
XPE_10645	ENOG41081UC	Inherit from COG: Competence protein
XPE_10650	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
XPE_10655	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
XPE_10665	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
XPE_10670	ENOG4105DTD	Dehydrogenase
XPE_10710	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
XPE_10715	ENOG4105MH3	Protein of unknown function (DUF2490)
XPE_10730	ENOG4107HP6	Transcriptional regulator
XPE_10745	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
XPE_10750	ENOG4105F2Z	3-oxoadipate enol-lactonase
XPE_10755	ENOG4107RAW	3-carboxy-cis-cis-muconate cycloisomerase
XPE_10770	ENOG4105CHU	acetyl-coa acetyltransferase
XPE_10795	ENOG4105E98	transcriptional regulator DeoR family
XPE_10800	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
XPE_10810	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
XPE_10820	ENOG41072AC	4-hydroxybenzoate 3-monooxygenase
XPE_10850	ENOG4105CPI	Metal Dependent Phosphohydrolase
XPE_10855	ENOG4105D2S	major facilitator superfamily
XPE_10865	ENOG4108Z0R	Transferase
XPE_10880	ENOG4105C01	Dihydroxy-acid dehydratase
XPE_10900	ENOG4105CMM	transposase
XPE_10910	ENOG4105CMM	transposase
XPE_10990	ENOG4105ECR	NmrA family
XPE_11000	ENOG4105CAX	The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity)
XPE_11020	ENOG4108UZX	fmn reductase
XPE_11025	ENOG4105DZ2	Transcriptional regulator
XPE_11030	ENOG4105WPN	DNA integration recombination invertion protein
XPE_11045	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
XPE_11050	ENOG4105BZS	acriflavin resistance protein
XPE_11055	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
XPE_11060	ENOG4105EB3	Histidine kinase
XPE_11065	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
XPE_11085	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
XPE_11090	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
XPE_11095	ENOG4107S9D	Alpha beta hydrolase
XPE_11105	ENOG4105D94	Major Facilitator Superfamily
XPE_11110	ENOG4106NZI	LysR family Transcriptional regulator
XPE_11125	ENOG4105F8V	Hydrolase, tatD family
XPE_11130	ENOG4105ETT	transcriptional Regulator, LysR family
XPE_11150	ENOG4105C7N	Xanthine uracil vitamin C permease
XPE_11160	ENOG4105DU0	nucleoside hydrolase
XPE_11170	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
XPE_11190	ENOG4105HEI	LysR family (Transcriptional regulator
XPE_11200	ENOG4105C5R	Aminotransferase
XPE_11220	ENOG4105E1J	oxidoreductase
XPE_11225	ENOG4105VT2	5-hydroxyisourate hydrolase
XPE_11230	ENOG4108W15	Protein of unknown function (DUF1456)
XPE_11240	ENOG4105CQ7	ATP-dependent helicase
XPE_11250	ENOG4108R99	pseudouridine synthase
XPE_11265	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
XPE_11285	ENOG4108ZHJ	Organic hydroperoxide resistance protein
XPE_11290	ENOG4105K56	Transcriptional regulator
XPE_11295	ENOG4105D6Z	AFG1 family ATPase
XPE_11305	ENOG4108TZV	Membrane
XPE_11315	ENOG4105CKI	cobalamin synthesis protein
XPE_11375	ENOG4105C1G	acyl-Coa dehydrogenase
XPE_11380	ENOG4107QX3	carboxylase
XPE_11410	ENOG4105BZU	Histidine kinase
XPE_11420	ENOG4107QP3	malate synthase g
XPE_11425	ENOG4107R11	Transcriptional regulator
XPE_11460	ENOG4105DGW	oligopeptidase A
XPE_11465	ENOG4105D44	asparaginase
XPE_11475	ENOG4108YZN	class I peptide chain release factor
XPE_11485	ENOG4105DR9	pseudouridine synthase
XPE_11495	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
XPE_11515	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
XPE_11520	ENOG410680H	amp-dependent synthetase and ligase
XPE_11525	ENOG4105PI0	Ferredoxin
XPE_11530	ENOG4108J2P	Alpha beta hydrolase fold
XPE_11535	ENOG4107R3N	Filamentation induced by cAMP protein fic
XPE_11540	ENOG4105E2T	synthase III
XPE_11555	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
XPE_11575	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
XPE_11580	ENOG4105BZU	Histidine kinase
XPE_11585	ENOG4105C7K	acetolactate synthase
XPE_11600	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
XPE_11605	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
XPE_11610	ENOG4107YZP	Rhodanese domain protein
XPE_11645	ENOG4105CHU	acetyl-coa acetyltransferase
XPE_11660	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
XPE_11665	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
XPE_11670	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
XPE_11675	ENOG4105CUX	Signal transduction histidine kinase
XPE_11680	ENOG4105BZU	Histidine kinase
XPE_11690	ENOG4105C5F	glutamine synthetase
XPE_11700	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
XPE_11740	ENOG4105KA0	thioesterase Superfamily protein
XPE_11745	ENOG4107RZC	phospholipase d
XPE_11755	ENOG4105M4E	phosphohistidine phosphatase, SixA
XPE_11760	ENOG4105D1F	ATP-binding protein
XPE_11810	ENOG4105E90	ABC transporter
XPE_11815	ENOG4108IJ8	ABC transporter
XPE_11830	ENOG4105DKW	ABC transporter
XPE_11840	ENOG4105CH2	amidohydrolase
XPE_11845	ENOG4105D78	K07001 NTE family protein
XPE_11850	ENOG4105CNM	Receptor
XPE_11855	ENOG4108YXU	transcriptional regulator AsnC family
XPE_11860	ENOG4105MIR	Phenylalanine 4-monooxygenase
XPE_11870	ENOG4107TDE	lipolytic protein G-D-S-L family
XPE_11880	ENOG4105CHR	reductase
XPE_11885	ENOG4105D50	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate (By similarity)
XPE_11890	ENOG4105ETE	Transcriptional regulator (LacI family
XPE_11895	ENOG4105DSG	hydrolase family 43
XPE_11900	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
XPE_11910	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
XPE_11925	ENOG4105EBR	Carboxylesterase
XPE_11945	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
XPE_11950	ENOG4105CG3	alpha amylase, catalytic region
XPE_11955	ENOG4105EP6	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity)
XPE_12030	ENOG4105D7K	pfkb domain protein
XPE_12040	ENOG4105RKW	reductase (By
XPE_12045	ENOG4108M3R	transcriptional activator CadC
XPE_12065	ENOG4108S01	response regulator
XPE_12070	ENOG4105BZU	Histidine kinase
XPE_12090	ENOG4105DMF	Dehydrogenase
XPE_12115	ENOG4105C26	Dehydrogenase
XPE_12130	ENOG4105CHB	tonB-dependent Receptor
XPE_12135	ENOG4105CGF	Aromatic amino acid aminotransferase
XPE_12140	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
XPE_12190	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
XPE_12230	ENOG4105CSH	Transporter
XPE_12240	ENOG4105K63	Thioredoxin
XPE_12265	ENOG4105D4Y	metalloprotease
XPE_12285	ENOG41067RQ	csbd family
XPE_12325	ENOG4105DYS	nad(p)h dehydrogenase (quinone)
XPE_12340	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
XPE_12345	ENOG4107FW0	short-chain dehydrogenase reductase
XPE_12365	ENOG4108UT2	hemolysin iii
XPE_12370	ENOG4108I5C	dEAD DEAH box helicase
XPE_12435	ENOG4105EXG	Transcriptional regulator
XPE_12465	ENOG4105CBC	glutamate synthase
XPE_12470	ENOG4105BZ8	glutamate synthase
XPE_12480	ENOG4105DQ4	alcohol dehydrogenase
XPE_12510	ENOG4107VAM	peptidase, m28
XPE_12520	ENOG41063SB	peptidase
XPE_12525	ENOG4105CN1	protease
XPE_12545	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
XPE_12570	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
XPE_12580	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
XPE_12615	ENOG4108K0D	peptidase, M48
XPE_12625	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
XPE_12630	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
XPE_12635	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
XPE_12640	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
XPE_12655	ENOG41067YR	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
XPE_12660	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
XPE_12665	ENOG4108ZJ4	polysaccharide deacetylase
XPE_12670	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
XPE_12685	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
XPE_12700	ENOG4105DU1	integral membrane protein, terc
XPE_12705	ENOG4105DR4	Methyltransferase
XPE_12720	ENOG4105CSP	Major Facilitator Superfamily
XPE_12725	ENOG4105BZW	Glycerate kinase
XPE_12730	ENOG4108IXP	Carbohydrate diacid transcriptional activator CdaR
XPE_12735	ENOG4105BZU	Histidine kinase
XPE_12740	ENOG4105NRM	Membrane
XPE_12750	ENOG4105CWX	Alpha-1,2-mannosidase
XPE_12755	ENOG4105CUB	amino acid
XPE_12775	ENOG4105EJC	lysr family transcriptional regulator
XPE_12780	ENOG4105CIS	alcohol dehydrogenase
XPE_12785	ENOG4107QSV	RmuC domain protein
XPE_12795	ENOG4108V06	Glutathione peroxidase
XPE_12805	ENOG410903C	(LipO)protein
XPE_12820	ENOG4107PE3	Mammalian cell entry related domain protein
XPE_12825	ENOG4105CY3	ABC transporter, permease
XPE_12830	ENOG4105DHJ	ABC, transporter
XPE_12865	ENOG4105DSY	exodeoxyribonuclease V, gamma
XPE_12870	ENOG4107QKA	exodeoxyribonuclease V beta
XPE_12880	ENOG41080ET	plasmid maintenance system killer protein
XPE_12885	ENOG4105VDM	plasmid maintenance system antidote protein, xre family
XPE_12930	ENOG4105CBZ	Short-chain dehydrogenase reductase Sdr
XPE_12940	ENOG4108SIC	Transcriptional regulator
XPE_12985	ENOG4105D3G	Pseudouridine synthase
XPE_13045	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
XPE_13050	ENOG4108UMS	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase (By similarity)
XPE_13055	ENOG4105EMU	Dehydrogenase
XPE_13060	ENOG410642W	LysR family Transcriptional regulator
XPE_13070	ENOG4105CSH	Transporter
XPE_13075	ENOG4105DR8	Membrane
XPE_13085	ENOG4105Y49	secretion protein, HlyD family
XPE_13090	ENOG4105ZQC	membrane protein AaeX
XPE_13100	ENOG4105EUJ	GTP cyclohydrolase i
XPE_13120	ENOG4105EJ9	Membrane
XPE_13125	ENOG4105K5B	UPF0225 protein
XPE_13135	ENOG4105DSB	aldose 1-epimerase
XPE_13155	ENOG4105DKK	Benzoate
XPE_13185	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
XPE_13195	ENOG4105DJ9	glucan biosynthesis protein
XPE_13200	ENOG4105BZU	Histidine kinase
XPE_13205	ENOG4107104	thymidine kinase
XPE_13210	ENOG4105C4R	Atp-dependent dna helicase
XPE_13225	ENOG4108YXG	UPF0502 protein
XPE_13235	ENOG4105CUR	5'-nucleotidase, lipoprotein e(p4) family
XPE_13240	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
XPE_13245	ENOG4105QV4	Tryptophan halogenase
XPE_13260	ENOG4105ETE	Transcriptional regulator (LacI family
XPE_13270	ENOG4105E55	glycerol-3-phosphate acyltransferase
XPE_13310	ENOG4105DT9	hydrolase family 43
XPE_13315	ENOG4105CT4	transporter
XPE_13345	ENOG4105D2H	Uronic isomerase
XPE_13350	ENOG4105CNT	hydrolase family 2
XPE_13355	ENOG4105D9F	endo-1,4-beta-xylanase (EC 3.2.1.8)
XPE_13385	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
XPE_13435	ENOG4105DEI	Mannitol dehydrogenase
XPE_13450	ENOG4105CXK	mandelate racemase muconate lactonizing
XPE_13460	ENOG4105D0H	Alpha-glucuronidase (EC 3.2.1.139)
XPE_13465	ENOG4105ETE	Transcriptional regulator (LacI family
XPE_13470	ENOG4105C93	Xylose Isomerase
XPE_13475	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
XPE_13480	ENOG4105DH7	May be involved in recombination (By similarity)
XPE_13500	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
XPE_13515	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
XPE_13520	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
XPE_13530	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
XPE_13545	ENOG4107QHF	type ii secretion system protein e
XPE_13550	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
XPE_13560	ENOG4107RDJ	Sulfotransferase
XPE_13570	ENOG4105D05	Receptor
XPE_13575	ENOG4105CFU	surface antigen
XPE_13580	ENOG4105MA0	exported protein
XPE_13605	ENOG4105CNA	YD repeat protein
XPE_13650	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
XPE_13655	ENOG4105CT4	transporter
XPE_13660	ENOG4105E2V	Glycosyltransferase 36
XPE_13675	ENOG4105BZU	Histidine kinase
XPE_13680	ENOG4108UI1	Probably functions as a manganese efflux pump (By similarity)
XPE_13690	ENOG4108K2P	TRANSCRIPTIONal
XPE_13695	ENOG4105EDR	glucose galactose transporter
XPE_13700	ENOG4105QJH	Domain of unknown function (DUF718)
XPE_13705	ENOG4105DIA	mandelate racemase muconate lactonizing
XPE_13715	ENOG4105ERH	Fumarylacetoacetate hydrolase
XPE_13720	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
XPE_13740	ENOG4105DSG	hydrolase family 43
XPE_13775	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
XPE_13785	ENOG41062QD	Membrane
XPE_13790	ENOG4107QN1	sodium solute
XPE_13800	ENOG4105CGK	Exodeoxyribonuclease III
XPE_13825	ENOG4105DGI	Alkaline phosphatase
XPE_13830	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
XPE_13855	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
XPE_13870	ENOG4105KDC	50s ribosomal protein l28
XPE_13875	ENOG4105W0E	50S ribosomal protein L33
XPE_13880	ENOG4105KHM	amidohydrolase 2
XPE_13895	ENOG4105JSC	dimethylmenaquinone methyltransferase
XPE_13900	ENOG4108KB2	LysR family Transcriptional regulator
XPE_13905	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
XPE_13920	ENOG4105C4R	Atp-dependent dna helicase
XPE_13955	ENOG4108WC9	type VI secretion system effector, hcp1 family
XPE_13985	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
XPE_14025	ENOG4105D6F	Phosphatase
XPE_14070	ENOG4105CS6	Rhs element vgr protein
XPE_14085	ENOG410642W	LysR family Transcriptional regulator
XPE_14090	ENOG4107S5I	aldo keto reductase
XPE_14115	ENOG4108ZF3	Phosphatase
XPE_14120	ENOG4107TPY	serine threonine protein kinase
XPE_14150	ENOG4105C2M	dna polymerase I
XPE_14155	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
XPE_14200	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
XPE_14210	ENOG4105E9Q	Acyl-transferase
XPE_14215	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
XPE_14275	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
XPE_14285	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
XPE_14300	ENOG4105BZP	glycoside hydrolase 15-related
XPE_14305	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
XPE_14330	ENOG4105CJW	magnesium transporter
XPE_14335	ENOG4105CD5	CoA-binding domain protein
XPE_14350	ENOG4107QYD	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
XPE_14360	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
XPE_14390	ENOG41063V1	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
XPE_14395	ENOG4105E3A	(ABC) transporter
XPE_14400	ENOG4105DA5	(ABC) transporter
XPE_14405	ENOG4107SC0	ferredoxin--NADP reductase
XPE_14430	ENOG4105VZ8	Transcriptional regulator
XPE_14440	ENOG4108IUW	ABC transporter
XPE_14455	ENOG4105QV4	Tryptophan halogenase
XPE_14475	ENOG4105CYM	Glutathione S-transferase
XPE_14505	ENOG4105D52	delta-aminolevulinic acid dehydratase
XPE_14525	ENOG4105E2X	shikimate dehydrogenase
XPE_14540	ENOG4105DVT	helicase
XPE_14550	ENOG4105CH6	catalase
XPE_14575	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
XPE_14585	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
XPE_14590	ENOG4105EB3	Histidine kinase
XPE_14620	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
XPE_14640	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
XPE_14680	ENOG4105VDW	Csbd family
XPE_14685	ENOG4105C31	Tryptophanyl-tRNA synthetase
XPE_14690	ENOG4108NNI	Beta-lactamase domain-containing protein
XPE_14710	ENOG4105FDR	Membrane
XPE_14735	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
XPE_14740	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
XPE_14745	ENOG4108ZGX	Histidine kinase
XPE_14750	ENOG4108S01	response regulator
XPE_14765	ENOG4107VGR	Catalase
XPE_14780	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
XPE_14785	ENOG4107URF	beta-phospho-glucomutase
XPE_14790	ENOG4105DSF	transport protein
XPE_14810	ENOG4105C0H	protease
XPE_14830	ENOG4105DHQ	Histidine kinase
XPE_14835	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
XPE_14840	ENOG4105ECP	epimerase
XPE_14875	ENOG4105E0Y	RtcB Protein
XPE_14895	ENOG4105EJ2	Transcriptional regulator
XPE_14910	ENOG41066DG	(EAL) domain protein
XPE_14925	ENOG4105C0P	Mg chelatase subunit ChlI
XPE_14930	ENOG4105W0Z	cytoplasmic protein
XPE_14935	ENOG4108YZA	Nitrogen regulatory protein pii
XPE_14945	ENOG4105CPE	K01197 hyaluronoglucosaminidase EC 3.2.1.35
XPE_14965	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
XPE_14970	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
XPE_14975	ENOG4105CEY	Amp-dependent synthetase and ligase
XPE_14985	ENOG4105EXC	Acyl-transferase
XPE_14990	ENOG4105EMU	Dehydrogenase
XPE_15005	ENOG4105C75	arginyL-tRNA synthetase
XPE_15010	ENOG4105W5Q	DNA repair protein (RadC
XPE_15015	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
XPE_15020	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
XPE_15040	ENOG4105CKK	Glycosyl transferase, family 2
XPE_15055	ENOG4105FA0	parb-like partition protein
XPE_15060	ENOG4107QJE	Chromosome Partitioning Protein
XPE_15070	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
XPE_15075	ENOG4105CGK	Exodeoxyribonuclease III
XPE_15080	ENOG4105EYM	Major Facilitator superfamily
XPE_15090	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
XPE_15095	ENOG4105DR5	peptidase
XPE_15100	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
XPE_15130	ENOG4105C26	Dehydrogenase
XPE_15140	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
XPE_15155	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
XPE_15160	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
XPE_15185	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
XPE_15195	ENOG4105DHU	Bile acid
XPE_15200	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
XPE_15205	ENOG4107S2Z	UPF0761 membrane protein
XPE_15215	ENOG4105KTH	gatB Yqey
XPE_15220	ENOG4105VCC	30S ribosomal protein S21
XPE_15225	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
XPE_15230	ENOG4107ZVW	dihydroneopterin aldolase
XPE_15235	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
XPE_15260	ENOG4105D5Q	Arginine ornithine antiporter
XPE_15270	ENOG4105DTQ	mandelate racemase muconate lactonizing
XPE_15280	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
XPE_15285	ENOG4108UQS	dipeptidase
XPE_15330	ENOG4105E32	cytoplasmic protein
XPE_15340	ENOG4105BZS	acriflavin resistance protein
XPE_15345	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
XPE_15350	ENOG4105CH2	amidohydrolase
XPE_15355	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
XPE_15360	ENOG4109066	lysm domain bon superfamily protein
XPE_15370	ENOG4105E9K	Isocitrate dehydrogenase
XPE_15380	ENOG4105ETT	transcriptional Regulator, LysR family
XPE_15385	ENOG4105VS7	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity)
XPE_15400	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
XPE_15405	ENOG4105K63	Thioredoxin
XPE_15410	ENOG4105C1J	atp-dependent rna helicase
XPE_15415	ENOG4105CAK	Cell division ATP-binding protein ftsE
XPE_15420	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
XPE_15425	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
XPE_15430	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
XPE_15435	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
XPE_15440	ENOG4105EN6	Membrane
XPE_15460	ENOG4108TGY	Glutathione S-transferase
XPE_15465	ENOG4105C25	Primosomal protein n'
XPE_15485	ENOG4107QI1	Mate efflux family protein
XPE_15490	ENOG4105D07	Signal peptide peptidase, SppA
XPE_15505	ENOG4107ZQV	short-chain dehydrogenase reductase
XPE_15520	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
XPE_15525	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
XPE_15540	ENOG4108RPN	Protein smg homolog
XPE_15545	ENOG4105C79	DNA protecting protein DprA
XPE_15550	ENOG4108WZM	domain protein
XPE_15555	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
XPE_15560	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
XPE_15565	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
XPE_15610	ENOG4108Z7F	N-acetyltransferase
XPE_15615	ENOG4105D1S	lipid A biosynthesis
XPE_15620	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
XPE_15625	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
XPE_15865	ENOG4105ED4	portal protein
XPE_15895	ENOG4105CBZ	Short-chain dehydrogenase reductase Sdr
XPE_15920	ENOG4105CMQ	Chloride channel
XPE_15925	ENOG4105CHH	sulfate transporter
XPE_15955	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
XPE_15960	ENOG4105HEI	LysR family (Transcriptional regulator
XPE_15980	ENOG4108UQ8	endoribonuclease L-psp
XPE_15995	ENOG4105CIG	ABC transporter
XPE_16055	ENOG4105E2A	Dehydrogenase
XPE_16070	ENOG4105BZ1	(ABC) transporter
XPE_16090	ENOG4105CMR	udp-glucose 4-epimerase
XPE_16095	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
XPE_16110	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
XPE_16115	ENOG4105C4M	(Ubiquinol oxidase) subunit I
XPE_16130	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
XPE_16145	ENOG4105BZU	Histidine kinase
XPE_16165	ENOG4105WEF	catalase
XPE_16170	ENOG4108Z9Z	response to DNA damage stimulus
XPE_16190	ENOG4105C2F	Histidine kinase
XPE_16195	ENOG4108VAC	response regulator
XPE_16205	ENOG4107QTZ	amino acid
XPE_16220	ENOG4105C9K	Endothelin-converting enzyme 1
XPE_16235	ENOG4105CPC	Aldo Keto reductase
XPE_16245	ENOG4105CBN	LysR family transcriptional regulator
XPE_16250	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
XPE_16260	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
XPE_16275	ENOG4105EEQ	Na H antiporter
XPE_16280	ENOG4105DA5	(ABC) transporter
XPE_16285	ENOG4105E3A	(ABC) transporter
XPE_16310	ENOG4105ER2	Ompa motb domain protein
XPE_16315	ENOG4107RD7	Flagellar Motor Protein, MotA
XPE_16335	ENOG4105EW9	transcriptional regulator AsnC family
XPE_16340	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
XPE_16345	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
XPE_16365	ENOG4105BZU	Histidine kinase
XPE_16385	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
XPE_16390	ENOG4105I08	Pseudouridine synthase
XPE_16395	ENOG4107YBY	Hydrolase
XPE_16400	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
XPE_16420	ENOG4105BZU	Histidine kinase
XPE_16430	ENOG4108VPT	UPF0234 protein
XPE_16435	ENOG4108EHX	EamA-like transporter family
XPE_16440	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
XPE_16445	ENOG4108UMI	ABC transporter, permease
XPE_16450	ENOG4105D01	(LipO)protein
XPE_16485	ENOG4107QSN	dihydrolipoamide acetyltransferase
XPE_16495	ENOG4107QN2	dihydrolipoyl dehydrogenase
XPE_16515	ENOG4107RAZ	it plays a direct role in the translocation of protons across the membrane (By similarity)
XPE_16520	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
XPE_16525	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
XPE_16530	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
XPE_16535	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
XPE_16540	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
XPE_16545	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
XPE_16550	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
XPE_16565	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
XPE_16570	ENOG4105BZU	Histidine kinase
XPE_16575	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
XPE_16585	ENOG4107RBB	ABC transporter, permease
XPE_16590	ENOG4107RBB	ABC transporter, permease
XPE_16595	ENOG4105C19	ABC transporter
XPE_16600	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
XPE_16605	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
XPE_16655	ENOG4105DGW	oligopeptidase A
XPE_16670	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
XPE_16680	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
XPE_16685	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
XPE_16700	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
XPE_16710	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
XPE_16715	ENOG4105C1J	atp-dependent rna helicase
XPE_16730	ENOG4108RXX	maleylacetoacetate isomerase
XPE_16735	ENOG4105CZX	twitching motility protein
XPE_16760	ENOG4105C28	cystathionine
XPE_16770	ENOG4105EY8	ABC transporter
XPE_16790	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
XPE_16800	ENOG4105IQ5	FAD linked oxidase domain protein
XPE_16815	ENOG4105C10	Electron transfer flavoprotein
XPE_16820	ENOG4105BZJ	Electron transfer flavoprotein
XPE_16835	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
XPE_16840	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
XPE_16850	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
XPE_16855	ENOG4107QKV	phosphomannomutase
XPE_16860	ENOG4107QP7	CoA-transferase subunit A
XPE_16875	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
XPE_16900	ENOG4108SNX	Mammalian cell entry related domain protein
XPE_16905	ENOG4105DHJ	ABC, transporter
XPE_16920	ENOG4105VFQ	Histone family protein nucleoid-structuring protein H-NS
XPE_16925	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
XPE_16935	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
XPE_16965	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
XPE_16980	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
XPE_16990	ENOG4108K5H	permease YjgP YjgQ family protein
XPE_17005	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
XPE_17015	ENOG4105T95	Thiol disulfide interChange protein
XPE_17025	ENOG4108ETH	Formylglycinamide ribotide synthetase
XPE_17030	ENOG4105EUR	Domain-Containing protein
XPE_17035	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
XPE_17040	ENOG4105EUR	Domain-Containing protein
XPE_17045	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
XPE_17050	ENOG4107QHF	type ii secretion system protein e
XPE_17060	ENOG4105D7Q	type ii secretion system
XPE_17070	ENOG4105WMT	general secretion pathway protein h
XPE_17080	ENOG41069G9	General secretion pathway protein J
XPE_17085	ENOG4105UV2	general secretion pathway protein K
XPE_17090	ENOG41090VX	general secretion pathway protein L
XPE_17095	ENOG410678M	general secretion pathway protein M
XPE_17105	ENOG4105GVR	general secretion pathway protein D
XPE_17115	ENOG4106S9K	Transcriptional regulator
XPE_17160	ENOG4107RH7	Nicotinate phosphoribosyltransferase
XPE_17175	ENOG4107QZ7	Cellulose synthase catalytic subunit
XPE_17180	ENOG4107EEX	Cellulose synthase regulator protein
XPE_17185	ENOG4105K2Z	endo-1,4-d-glucanase (EC 3.2.1.4)
XPE_17190	ENOG4105EJG	cellulose synthase
XPE_17220	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
XPE_17225	ENOG4108RMV	DegV Family
XPE_17250	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
XPE_17255	ENOG41069H0	dihydroorotase EC 3.5.2.3
XPE_17290	ENOG4105CHM	Aminotransferase
XPE_17295	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
XPE_17310	ENOG4107QW3	Sucrose phosphorylase
XPE_17325	ENOG4105ETE	Transcriptional regulator (LacI family
XPE_17330	ENOG4105CHR	reductase
XPE_17335	ENOG4105D4T	Citrate transporter
XPE_17355	ENOG4105DHQ	Histidine kinase
XPE_17360	ENOG4106JDA	Phosphoglycerate transport regulatory protein PGTC
XPE_17365	ENOG4105WH1	Two component transcriptional regulator luxr family
XPE_17380	ENOG4105CPC	Aldo Keto reductase
XPE_17385	ENOG4105F04	LysR family Transcriptional regulator
XPE_17395	ENOG4105CSH	Transporter
XPE_17400	ENOG4105CQZ	Histidine kinase
XPE_17410	ENOG4105CK2	sodium dicarboxylate symporter
XPE_17415	ENOG4105C6K	Malic enzyme
XPE_17440	ENOG4105D1S	lipid A biosynthesis
XPE_17450	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
XPE_17455	ENOG4105DFG	type I secretion outer membrane protein
XPE_17460	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
XPE_17470	ENOG4105BZU	Histidine kinase
XPE_17475	ENOG4108MP6	LysR family Transcriptional regulator
XPE_17480	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
XPE_17485	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
XPE_17490	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
XPE_17495	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
XPE_17500	ENOG4105C7B	Threonine dehydratase
XPE_17515	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
XPE_17520	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
XPE_17540	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
XPE_17545	ENOG4108M3R	transcriptional activator CadC
XPE_17550	ENOG4105ECQ	AraC Family Transcriptional Regulator
XPE_17565	ENOG4105F0N	pyrophosphate phospho-hydrolase
XPE_17575	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
XPE_17590	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
XPE_17595	ENOG4105DFU	Cell wall formation (By similarity)
XPE_17605	ENOG4105FFC	UPF0187 protein
XPE_17610	ENOG410841Q	phosphoesterase PA-phosphatase related protein
XPE_17625	ENOG4105EYW	Ion transport protein
XPE_17630	ENOG4105C8Y	Acetylornithine aminotransferase
XPE_17660	ENOG4105CIH	Imidazole acetol-phosphate transaminase
XPE_17665	ENOG41090JD	Blue (Type 1) copper domain protein
XPE_17670	ENOG41061ZR	Transcriptional regulator
XPE_17680	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
XPE_17700	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
XPE_17705	ENOG4105VCQ	rubredoxin
XPE_17710	ENOG41063JG	Transcriptional regulator
XPE_17720	ENOG4105E66	phosphoriboisomerase A
XPE_17730	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
XPE_17740	ENOG4105W8B	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
XPE_17750	ENOG4105E07	UPF0149 protein
XPE_17755	ENOG4107RAQ	aminopeptidase
XPE_17765	ENOG4105D9Y	Splits dipeptides with a prolyl residue in the C- terminal position (By similarity)
XPE_17780	ENOG4105CSA	Coproporphyrinogen iii oxidase
XPE_17785	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
XPE_17795	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
XPE_17800	ENOG4105DSJ	YicC domain protein
XPE_17805	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
XPE_17810	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
XPE_17815	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
XPE_17820	ENOG4105KME	endoribonuclease L-psp
XPE_17825	ENOG4105CB5	ATP-dependent DNA helicase recG
XPE_17830	ENOG4105DU0	nucleoside hydrolase
XPE_17835	ENOG4105NRA	50s ribosomal protein l31 type b
XPE_17850	ENOG4108JQC	penicillin-binding protein 1A
XPE_17875	ENOG4105E4G	Type IV pilus
XPE_17880	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
XPE_17900	ENOG4107QVM	von Willebrand factor, type A
XPE_17915	ENOG4105CK2	sodium dicarboxylate symporter
XPE_17920	ENOG4105CV1	Transketolase (EC 2.2.1.1)
XPE_17925	ENOG4105CNM	Receptor
XPE_17930	ENOG4105DR5	peptidase
XPE_17935	ENOG4107Y2H	ErfK ybiS ycfS ynhG family protein
XPE_17970	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
XPE_17975	ENOG4105E0C	molybdate abc transporter
XPE_17980	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
XPE_17995	ENOG4105EIF	outer membrane protein W
XPE_18010	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
XPE_18030	ENOG4105BZA	Phosphoglycerate kinase
XPE_18040	ENOG4105CA9	Pyruvate kinase
XPE_18045	ENOG4107R1Y	fructose-bisphosphate aldolase
XPE_18050	ENOG4108UVJ	appr-1-p processing domain protein
XPE_18065	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
XPE_18070	ENOG4107R11	Transcriptional regulator
XPE_18090	ENOG4105BZU	Histidine kinase
XPE_18110	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
XPE_18115	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
XPE_18120	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
XPE_18125	ENOG4105C11	sulfate adenylyltransferase), subunit 2
XPE_18130	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
XPE_18145	ENOG4105BZS	acriflavin resistance protein
XPE_18150	ENOG4105CD8	aminopeptidase N
XPE_18165	ENOG4105C2N	RNA methyltransferase TrmH family group 3
XPE_18195	ENOG4105ETE	Transcriptional regulator (LacI family
XPE_18205	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
XPE_18235	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
XPE_18240	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
XPE_18285	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
XPE_18295	ENOG4105ETX	regulatoR
XPE_18300	ENOG4105BZU	Histidine kinase
XPE_18305	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
XPE_18310	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
XPE_18345	ENOG4107T8Q	Glycosyl transferase (Group 1
XPE_18355	ENOG4107QHF	type ii secretion system protein e
XPE_18360	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
XPE_18365	ENOG4107TUY	Histidine kinase
XPE_18370	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
XPE_18375	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
XPE_18390	ENOG4105C4K	Nad synthetase
XPE_18400	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XPE_18405	ENOG4105C34	Pseudouridine synthase
XPE_18420	ENOG4105KIR	Thiol-disulfide oxidoreductase dcc
XPE_18425	ENOG4105C8Q	Methyl-accepting chemotaxis
XPE_18430	ENOG4105DZG	Dehydrogenase
XPE_18435	ENOG4105C1K	alpha-alpha-trehalose-phosphate synthase
XPE_18440	ENOG4105BZP	glycoside hydrolase 15-related
XPE_18445	ENOG4108K4C	ec 3.1.3.12
XPE_18450	ENOG4107RNH	Outer membrane receptor FepA
XPE_18490	ENOG4105E2Y	ABC, transporter
XPE_18500	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
XPE_18505	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
XPE_18520	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
XPE_18525	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
XPE_18530	ENOG4105EFT	decarboxylase
XPE_18535	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
XPE_18540	ENOG4108YZT	Adenosylcobinamide kinase
XPE_18545	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
XPE_18570	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
XPE_18580	ENOG4105C6X	Major Facilitator
XPE_18595	ENOG4105GAV	receptor
XPE_18620	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
XPE_18635	ENOG4107RNH	Outer membrane receptor FepA
XPE_18640	ENOG4107RNH	Outer membrane receptor FepA
XPE_18655	ENOG4107RNH	Outer membrane receptor FepA
XPE_18660	ENOG4105C5H	ABC transporter
XPE_18670	ENOG4105ETT	transcriptional Regulator, LysR family
XPE_18685	ENOG4105HSS	phospholipase C
XPE_18700	ENOG4108ISG	Major Facilitator
XPE_18715	ENOG4105C9M	aspartyl-trna synthetase
XPE_18745	ENOG4105CDY	transcriptional regulatory protein
XPE_18750	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
XPE_18755	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
XPE_18760	ENOG4105DFH	Transport of potassium into the cell (By similarity)
XPE_18770	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
XPE_18775	ENOG4107YD3	Thioesterase
XPE_18780	ENOG4105E02	MotA TolQ exbB proton channel
XPE_18795	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
XPE_18800	ENOG4105KCK	Peptidoglycan-associated lipoprotein
XPE_18810	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
XPE_18825	ENOG410903D	sensor protein
XPE_18845	ENOG4105C8Q	Methyl-accepting chemotaxis
XPE_18885	ENOG4105C9U	ATP-dependent DNA helicase RecQ
XPE_18895	ENOG4105CQ7	ATP-dependent helicase
XPE_18905	ENOG4105CHC	glucokinase (EC 2.7.1.2)
XPE_18925	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
XPE_18930	ENOG4105Z85	coenzyme PQQ synthesis
XPE_18935	ENOG41086XE	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ (By similarity)
XPE_18940	ENOG4105JIE	May be involved in the transport of PQQ or its precursor to the periplasm (By similarity)
XPE_18945	ENOG410698T	Required for coenzyme pyrroloquinoline quinone (PQQ) biosynthesis. PQQ is probably formed by cross-linking a specific glutamate to a specific tyrosine residue and excising these residues from the peptide (By similarity)
XPE_18950	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
XPE_18970	ENOG4105BZ4	penicillin-binding protein
XPE_18980	ENOG4105DVT	helicase
XPE_18985	ENOG41072GX	Peptidase M22 Glycoprotease
XPE_18990	ENOG41065RQ	ADP-ribosylation crystallin J1
XPE_19025	ENOG4105D7Z	glutathione synthase
XPE_19030	ENOG4108UNF	response regulator
XPE_19035	ENOG4105M3Z	response regulator
XPE_19040	ENOG410807Z	Modulation of CheA activity in response to attractants (Chemotaxis
XPE_19045	ENOG4105C8Q	Methyl-accepting chemotaxis
XPE_19050	ENOG4105CBS	Chea signal transduction histidine kinase
XPE_19065	ENOG4105D9U	N-acetyltransferase
XPE_19080	ENOG4105JVQ	RNA Polymerase
XPE_19085	ENOG4105CP2	von willebrand factor, type a
XPE_19095	ENOG4106N3A	copper homeostasis protein cutc
XPE_19140	ENOG4105CWX	Alpha-1,2-mannosidase
XPE_19165	ENOG4105VRS	hydrolase family 18
XPE_19180	ENOG4105CHC	glucokinase (EC 2.7.1.2)
XPE_19185	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
XPE_19195	ENOG4107RK2	ADP-ribose diphosphatase NudE
XPE_19200	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
XPE_19205	ENOG4105DXN	mazG family
XPE_19210	ENOG4105KK4	UPF0060 membrane protein
XPE_19225	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
XPE_19230	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
XPE_19255	ENOG4107QPN	acyl-Coa dehydrogenase
XPE_19265	ENOG4108IG5	Transcriptional regulator
XPE_19280	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
XPE_19285	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
XPE_19295	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
XPE_19300	ENOG41066T0	asmA family
XPE_19305	ENOG4108UT2	hemolysin iii
XPE_19310	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
XPE_19315	ENOG4105DR5	peptidase
XPE_19320	ENOG4106TYC	homoserine o-acetyltransferase (EC 2.3.1.31)
XPE_19325	ENOG4105C28	cystathionine
XPE_19330	ENOG4105CFH	Aspartokinase
XPE_19345	ENOG4105EJQ	L-serine dehydratase
XPE_19365	ENOG4108YYC	ycei family
XPE_19370	ENOG4105BZU	Histidine kinase
XPE_19375	ENOG4105BZU	Histidine kinase
XPE_19380	ENOG4105BZU	Histidine kinase
XPE_19385	ENOG4105BZU	Histidine kinase
XPE_19390	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
XPE_19395	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
XPE_19405	ENOG4105D49	3-dehydroquinate synthase
XPE_19410	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
XPE_19415	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
XPE_19425	ENOG4108P9J	Phage shock protein A
XPE_19450	ENOG4106032	Glutathionylspermidine synthase
XPE_19460	ENOG4108Z4X	TRANSCRIPTIONal
XPE_19525	ENOG4108MHS	Lysyl endopeptidase
XPE_19550	ENOG4105CUB	amino acid
XPE_19575	ENOG4108NFF	pectate lyase
XPE_19580	ENOG4105C85	amino acid
XPE_19590	ENOG4105C4M	(Ubiquinol oxidase) subunit I
XPE_19595	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
XPE_19600	ENOG4107UWA	esterase
XPE_19605	ENOG4105CJW	magnesium transporter
XPE_19615	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
XPE_19620	ENOG41080Z8	PHOSPHOCARRIER protein
XPE_19630	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
XPE_19635	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
XPE_19640	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
XPE_19645	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
XPE_19650	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
XPE_19655	ENOG4108IUZ	ABC transporter
XPE_19660	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
XPE_19670	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
XPE_19675	ENOG4105C2X	Arabinose 5-phosphate isomerase
XPE_19685	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
XPE_19705	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
XPE_19715	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
XPE_19725	ENOG4105C02	permease
XPE_19735	ENOG4108S0S	Nucleotidyl transferase
XPE_19740	ENOG4105EHM	Aminoglycoside phosphotransferase
XPE_19755	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
XPE_19770	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
XPE_19775	ENOG4105CJ2	(LipO)protein
XPE_19800	ENOG4107E2E	PKHD-type hydroxylase
XPE_19805	ENOG4108IU3	tonb-dependent siderophore receptor
XPE_19815	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
XPE_19820	ENOG4105C9B	Cysteine desulfurase
XPE_19825	ENOG4105JRK	feS assembly protein SufD
XPE_19830	ENOG4105C3K	feS assembly ATPase SufC
XPE_19850	ENOG4108Z0Z	intracellular protease Pfpi family
XPE_19870	ENOG4105FAA	peptidase M23
XPE_19880	ENOG4105II7	pyrroline-5-carboxylate reductase
XPE_19885	ENOG4105DFA	alanine racemase domain protein
XPE_19890	ENOG4105CZX	twitching motility protein
XPE_19895	ENOG4105CZX	twitching motility protein
XPE_19915	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
XPE_19925	ENOG4108UJU	UPF0301 protein
XPE_19930	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
XPE_19935	ENOG4105CXT	aspartate transcarbamylase
XPE_19940	ENOG4108Z9K	Osmotically inducible protein
XPE_19950	ENOG4105JAB	phenazine biosynthesis protein, phzf family
XPE_19955	ENOG4105JAB	phenazine biosynthesis protein, phzf family
XPE_19960	ENOG4105CFH	Aspartokinase
XPE_19975	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
XPE_19990	ENOG4105EAH	synthase
XPE_19995	ENOG4108UUM	single-stranded DNA-binding protein
XPE_20010	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
XPE_20015	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
XPE_20020	ENOG4105C7W	Xanthine dehydrogenase
XPE_20025	ENOG4107XAN	XdhC and CoxI family
XPE_20065	ENOG4105VCD	cytoplasmic protein
XPE_20070	ENOG4105D22	carbon starvation protein
XPE_20075	ENOG4105EUB	pirin domain protein
XPE_20090	ENOG4105EUB	pirin domain protein
XPE_20105	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
XPE_20110	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
XPE_20120	ENOG4105C9K	Endothelin-converting enzyme 1
XPE_20125	ENOG4107RZC	phospholipase d
XPE_20130	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
XPE_20135	ENOG4105BZU	Histidine kinase
XPE_20140	ENOG4105BZU	Histidine kinase
XPE_20145	ENOG4108V3W	Chemotaxis protein, CheW
XPE_20150	ENOG4105C8Q	Methyl-accepting chemotaxis
XPE_20160	ENOG4105CBS	Chea signal transduction histidine kinase
XPE_20170	ENOG4108JA2	transcriptioN-repair coupling factor
XPE_20180	ENOG4105D6S	protein involved in catabolism of external DNA
XPE_20185	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
XPE_20190	ENOG4105EB3	Histidine kinase
XPE_20200	ENOG4105CT7	inner membrane cred family protein
XPE_20225	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
XPE_20230	ENOG4105MYN	Zinc uptake regulation protein
XPE_20240	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
XPE_20245	ENOG4105BZS	acriflavin resistance protein
XPE_20250	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
XPE_20255	ENOG4108JGH	Tetr family transcriptional regulator
XPE_20260	ENOG4105EQ2	LysR family Transcriptional regulator
XPE_20270	ENOG4105CF7	AraC family transcriptional regulator
XPE_20280	ENOG4105CC0	LysR family Transcriptional regulator
XPE_20285	ENOG4105F27	Major Facilitator
XPE_20290	ENOG4108FN7	Aldo keto reductase
XPE_20320	ENOG4105UGU	tonB-dependent Receptor
XPE_20395	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
XPE_20405	ENOG4105BZU	Histidine kinase
XPE_20410	ENOG4105FE9	pseudouridine synthase
XPE_20415	ENOG4105BZU	Histidine kinase
XPE_20435	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
XPE_20440	ENOG4105FQP	Beta-lactamase
XPE_20450	ENOG4105BZU	Histidine kinase
XPE_20455	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
XPE_20460	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
XPE_20490	ENOG4105BZ1	(ABC) transporter
XPE_20530	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
XPE_20535	ENOG4105WG9	Conserved Protein
XPE_20565	ENOG4107QR8	Thioredoxin
XPE_20575	ENOG4105C8T	Leucyl-tRNA synthetase
XPE_20590	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
XPE_20605	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
XPE_20615	ENOG4105MPN	Membrane
XPE_20620	ENOG4108Z03	MAF-like protein
XPE_20625	ENOG4105C03	ribonuclease
XPE_20630	ENOG4105QD6	exported protein
XPE_20640	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
XPE_20645	ENOG4105N42	UPF0307 protein
XPE_20650	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
XPE_20665	ENOG4105CTB	Polyprenyl synthetase
XPE_20670	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
XPE_20675	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
XPE_20685	ENOG4105G6Z	alkaline phosphatase
XPE_20705	ENOG4105K4H	Nlp p60 protein
XPE_20710	ENOG4105K4H	Nlp p60 protein
XPE_20715	ENOG4108YZY	peptidylprolyl cis-trans isomerase
XPE_20725	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
XPE_20730	ENOG4105DC8	reductase
XPE_20750	ENOG4105C9K	Endothelin-converting enzyme 1
XPE_20760	ENOG4105C9K	Endothelin-converting enzyme 1
XPE_20795	ENOG4105DHP	deoxycytidine triphosphate deaminase
XPE_20820	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
XPE_20825	ENOG4108RRZ	Transcription elongation factor GreB
XPE_20845	ENOG4107VIJ	nudix hydrolase
XPE_20850	ENOG4105D7A	ATP-binding protein
XPE_20860	ENOG4105DJ4	phosphatidylserine decarboxylase
XPE_20870	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
XPE_20875	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
XPE_20880	ENOG4105C5I	Dehydrogenase
XPE_20885	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
XPE_20900	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
XPE_20905	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
XPE_20915	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
XPE_20925	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
XPE_20930	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
XPE_20935	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
XPE_20950	ENOG4105BZU	Histidine kinase
XPE_20965	ENOG4105EMU	Dehydrogenase
XPE_20970	ENOG4105CP7	Triose-phosphate isomerase
XPE_20985	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
XPE_20990	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
XPE_20995	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
XPE_21000	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
XPE_21005	ENOG4105GKE	subunit e
XPE_21010	ENOG4107QIZ	NADH dehydrogenase
XPE_21015	ENOG4108IEH	NADH dehydrogenase subunit g
XPE_21020	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
XPE_21025	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
XPE_21030	ENOG4105DF2	NADH dehydrogenase subunit j
XPE_21040	ENOG4105D65	subunit l
XPE_21045	ENOG4105C8S	subunit m
XPE_21050	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
XPE_21060	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
XPE_21065	ENOG4105CHV	Transcription elongation factor NusA
XPE_21070	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
XPE_21075	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
XPE_21080	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
XPE_21085	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
XPE_21090	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
XPE_21100	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
XPE_21110	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
XPE_21115	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
XPE_21120	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
XPE_21125	ENOG4105M2J	Glutaredoxin
XPE_21135	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
XPE_21140	ENOG4108KPZ	tonB-dependent Receptor
XPE_21145	ENOG4105EWT	decarboxylase family
XPE_21150	ENOG4108HRK	Histidine kinase
XPE_21180	ENOG4105X0D	Fimbrial protein
XPE_21195	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
XPE_21235	ENOG4105CMA	conjugation trbi family protein
XPE_21255	ENOG4106E4H	Type IV secretory pathway VirB3 family protein
XPE_21320	ENOG4105CG3	alpha amylase, catalytic region
XPE_21345	ENOG4107RBJ	symporter
XPE_21355	ENOG4105ETE	Transcriptional regulator (LacI family
XPE_21360	ENOG4105C22	threonyL-tRNA synthetase
XPE_21365	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
XPE_21370	ENOG41082NX	50s ribosomal protein l35
XPE_21375	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
XPE_21380	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
XPE_21385	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
XPE_21390	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
XPE_21395	ENOG4105WJX	transcriptional regulator MERR family
XPE_21415	ENOG4105D3Q	Sugar transferase
XPE_21440	ENOG4107Y2G	Glycosyl transferase (Group 1
XPE_21450	ENOG4108NQK	Catalyzes the transfer of a glucuronic acid (GlcA) residue from UDP-glucuronate to mannose-alpha-1,3-glucose-beta- 1,4-glucose-P-P-polyisoprenyl to form the lipid-linked tetrasaccharide GlcA-Man-Glc(2)-PP-Pol, with a glucuronic acid- beta-mannose linkage. Is involved in the biosynthesis of the exopolysaccharide xanthan, since it catalyzes the fourth glycosylation step in the assembly of the pentasaccharide-P-P- polyisoprenyl repeating unit of xanthan. Is unable to use the trisaccharide acceptor freed from the pyrophosphate lipid moiety. Does not show specificity for the lipidic portion of the acceptor. Shows diminished activity when tested with 6-O-acetyl-mannose- alpha-1,3-glucose-beta-1,4-glucose-P-P-polyisoprenyl, a
XPE_21475	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
XPE_21480	ENOG4108JMX	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
XPE_21485	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
XPE_21505	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
XPE_21515	ENOG4105CSU	acyl-Coa dehydrogenase
XPE_21525	ENOG4105QNF	Outer membrane lipoprotein
XPE_21540	ENOG4105DKD	Incises the DNA at the 3' side of a lesion during nucleotide excision repair. Incises the DNA farther away from the lesion than UvrC. Not able to incise the 5' site of a lesion. When a lesion remains because UvrC is not able to induce the 3' incision, Cho incises the DNA. Then UvrC makes the 5' incision. The combined action of Cho and UvrC broadens the substrate range of nucleotide excision repair (By similarity)
XPE_21555	ENOG4105CQZ	Histidine kinase
XPE_21565	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
XPE_21570	ENOG4105CEN	a g-specific adenine glycosylase
XPE_21580	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
XPE_21590	ENOG4105CTU	Proline racemase
XPE_21595	ENOG41080HI	glycine oxidase
XPE_21610	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
XPE_21620	ENOG4105DC7	peptidase M24
XPE_21635	ENOG4107QTZ	amino acid
XPE_21705	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
XPE_21710	ENOG4106H78	methyltransferase
XPE_21715	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
XPE_21730	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
XPE_21735	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
XPE_21740	ENOG4105E08	Glycoside hydrolase, family 9
XPE_21745	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)