locus-tag	class	description
XbC2_100	COG1051	belongs to the nudix hydrolase family
XbC2_100	COG1056	cytidyltransferase-related domain
XbC2_109	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
XbC2_112	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
XbC2_122	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
XbC2_123	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
XbC2_133	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
XbC2_133	COG1328	CTP reductase activity
XbC2_148	COG0863	Belongs to the N(4) N(6)-methyltransferase family
XbC2_157	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
XbC2_169	COG1435	thymidine kinase activity
XbC2_189	COG0617	tRNA 3'-terminal CCA addition
XbC2_191	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
XbC2_220	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
XbC2_229	COG0494	nUDIX hydrolase
XbC2_232	COG0542	response to heat
XbC2_264	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
XbC2_268	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
XbC2_268	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
XbC2_299	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
XbC2_310	COG0328	RNA-DNA hybrid ribonuclease activity
XbC2_311	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
XbC2_314	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
XbC2_315	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
XbC2_320	COG0187	DNA topoisomerase II activity
XbC2_348	COG1397	ADP-ribosylglycohydrolase
XbC2_538	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
XbC2_57	COG0196	riboflavin kinase activity
XbC2_86	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP