locus-tag	class	description
MP631_00020	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MP631_00045	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
MP631_00065	COG3328	transposase activity
MP631_00115	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
MP631_00130	COG0129	dihydroxy-acid dehydratase activity
MP631_00185	COG1733	regulation of RNA biosynthetic process
MP631_00190	COG0702	epimerase
MP631_00225	COG0583	DNA-binding transcription factor activity
MP631_00230	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MP631_00255	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MP631_00260	COG2205	protein histidine kinase activity
MP631_00265	COG0745	RESPONSE REGULATOR receiver
MP631_00285	COG1902	pentaerythritol trinitrate reductase activity
MP631_00290	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
MP631_00310	COG0583	DNA-binding transcription factor activity
MP631_00325	COG0084	hydrolase, TatD family'
MP631_00380	COG0583	DNA-binding transcription factor activity
MP631_00390	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
MP631_00420	COG4807	Protein conserved in bacteria
MP631_00435	COG1187	pseudouridine synthase activity
MP631_00470	COG1764	response to oxidative stress
MP631_00475	COG1846	Transcriptional regulator
MP631_00480	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
MP631_00490	COG0697	spore germination
MP631_00555	COG1960	acyl-CoA dehydrogenase activity
MP631_00560	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MP631_00565	COG4770	biotin carboxylase activity
MP631_00580	COG3328	transposase activity
MP631_00590	COG3039	Transposase
MP631_00605	COG3328	transposase activity
MP631_00635	COG0475	glutathione-regulated potassium exporter activity
MP631_00670	COG0339	signal peptide processing
MP631_00705	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
MP631_00715	COG1181	Belongs to the D-alanine--D-alanine ligase family
MP631_00730	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MP631_00740	COG0727	PFAM Uncharacterised protein family (UPF0153)
MP631_00750	COG3177	Filamentation induced by cAMP protein fic
MP631_00755	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MP631_00770	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
MP631_00795	COG2205	protein histidine kinase activity
MP631_00825	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
MP631_00830	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MP631_00865	COG0183	Belongs to the thiolase family
MP631_00880	COG2032	superoxide dismutase activity
MP631_00885	COG2032	superoxide dismutase activity
MP631_00895	COG3852	Histidine kinase
MP631_00900	COG0004	ammonium transporteR
MP631_00905	COG0347	Belongs to the P(II) protein family
MP631_00910	COG0174	glutamine synthetase
MP631_00915	COG1968	undecaprenyl-diphosphatase activity
MP631_00965	COG2062	phosphohistidine phosphatase, SixA
MP631_00970	COG0489	protein tyrosine kinase activity
MP631_01015	COG1125	glycine betaine transport
MP631_01015	COG0517	IMP dehydrogenase activity
MP631_01030	COG1119	ATPase activity
MP631_01055	COG3186	Phenylalanine-4-hydroxylase
MP631_01065	COG2755	lipolytic protein G-D-S-L family
MP631_01080	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
MP631_01085	COG1609	Transcriptional regulator
MP631_01110	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
MP631_01140	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MP631_01145	COG0366	Alpha amylase catalytic
MP631_01150	COG0366	Alpha amylase catalytic
MP631_01165	COG3039	Transposase
MP631_01170	COG3039	Transposase
MP631_01185	COG3328	transposase activity
MP631_01250	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
MP631_01275	COG2197	response regulator
MP631_01280	COG4585	Histidine kinase
MP631_01285	COG1755	Isoprenylcysteine carboxyl methyltransferase
MP631_01290	COG1304	FMN binding
MP631_01365	COG0714	Associated with various cellular activities
MP631_01410	COG0477	Major facilitator Superfamily
MP631_01415	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MP631_01460	COG3237	CsbD-like
MP631_01470	COG3039	Transposase
MP631_01480	COG3039	Transposase
MP631_01520	COG0300	oxidoreductase activity
MP631_01540	COG1272	protein, Hemolysin III
MP631_01640	COG0493	'glutamate synthase
MP631_01660	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
MP631_01685	COG2234	aminopeptidase activity
MP631_01695	COG4942	peptidase
MP631_01700	COG0793	Belongs to the peptidase S41A family
MP631_01705	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MP631_01750	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MP631_01760	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
MP631_01775	COG1196	nuclear chromosome segregation
MP631_01785	COG1196	nuclear chromosome segregation
MP631_01895	COG3328	transposase activity
MP631_01935	COG3318	Belongs to the UPF0149 family
MP631_01935	COG3012	SEC-C Motif Domain Protein
MP631_01950	COG3328	transposase activity
MP631_02000	COG0187	DNA topoisomerase II activity
MP631_02005	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MP631_02025	COG0594	ribonuclease P activity
MP631_02030	COG0706	membrane insertase activity
MP631_02040	COG0726	polysaccharide deacetylase
MP631_02045	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MP631_02060	COG0584	glycerophosphoryl diester phosphodiesterase
MP631_02070	COG0861	Integral membrane protein TerC family
MP631_02095	COG1929	Belongs to the glycerate kinase type-1 family
MP631_02100	COG3835	regulator
MP631_02145	COG0583	DNA-binding transcription factor activity
MP631_02155	COG1322	Protein conserved in bacteria
MP631_02200	COG0511	ligase activity, forming carbon-carbon bonds
MP631_02230	COG1028	Short-chain dehydrogenase reductase Sdr
MP631_02325	COG1127	ABC transporter
MP631_02330	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MP631_02335	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
MP631_02350	COG2853	Lipoprotein
MP631_02625	COG3012	SEC-C Motif Domain Protein
MP631_02695	COG3328	transposase activity
MP631_02720	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MP631_02735	COG0583	DNA-binding transcription factor activity
MP631_02745	COG0477	Major facilitator Superfamily
MP631_02760	COG1566	PFAM secretion protein HlyD family protein
MP631_02775	COG0302	gtp cyclohydrolase
MP631_02795	COG3328	transposase activity
MP631_02805	COG0730	response to heat
MP631_02870	COG3328	transposase activity
MP631_02910	COG3012	SEC-C Motif Domain Protein
MP631_02920	COG0676	glucose-6-phosphate 1-epimerase activity
MP631_02975	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
MP631_03000	COG0210	DNA helicase
MP631_03015	COG0210	DNA helicase
MP631_03065	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MP631_03085	COG0284	orotidine-5'-phosphate decarboxylase activity
MP631_03115	COG2937	Belongs to the GPAT DAPAT family
MP631_03185	COG2211	Major facilitator Superfamily
MP631_03200	COG3693	PFAM glycoside hydrolase, family 10
MP631_03215	COG3693	PFAM glycoside hydrolase, family 10
MP631_03220	COG1904	glucuronate isomerase
MP631_03235	COG3386	PFAM SMP-30 Gluconolaconase
MP631_03330	COG4948	Mandelate Racemase Muconate Lactonizing
MP631_03340	COG3661	Belongs to the glycosyl hydrolase 67 family
MP631_03355	COG2115	Belongs to the xylose isomerase family
MP631_03360	COG0037	tRNA processing
MP631_03365	COG2974	May be involved in recombination
MP631_03395	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MP631_03405	COG0805	protein transport
MP631_03420	COG0518	GMP synthase (glutamine-hydrolyzing) activity
MP631_03420	COG0519	Catalyzes the synthesis of GMP from XMP
MP631_03435	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MP631_03440	COG0752	glycyl-tRNA synthetase alpha subunit
MP631_03455	COG4771	TonB-dependent receptor
MP631_03460	COG0729	surface antigen
MP631_03485	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MP631_03490	COG3265	gluconokinase activity
MP631_03495	COG2211	Major facilitator Superfamily
MP631_03500	COG3459	Glycosyltransferase 36 associated
MP631_03510	COG2205	protein histidine kinase activity
MP631_03515	COG1971	Probably functions as a manganese efflux pump
MP631_03530	COG1414	Transcriptional regulator
MP631_03545	COG4948	Mandelate Racemase Muconate Lactonizing
MP631_03550	COG0179	Fumarylacetoacetate (FAA) hydrolase
MP631_03555	COG1028	Short-chain dehydrogenase reductase Sdr
MP631_03575	COG3507	Belongs to the glycosyl hydrolase 43 family
MP631_03625	COG3162	membrane
MP631_03630	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MP631_03650	COG1940	carbohydrate kinase activity
MP631_03650	COG1846	Transcriptional regulator
MP631_03670	COG2091	lysine biosynthetic process via aminoadipic acid
MP631_03685	COG0357	Ribosomal RNA small subunit methyltransferase G
MP631_03705	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MP631_03730	COG2159	amidohydrolase
MP631_03740	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
MP631_03750	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MP631_03765	COG0210	DNA helicase
MP631_03840	COG3328	transposase activity
MP631_03865	COG0154	amidase activity
MP631_03935	COG0583	DNA-binding transcription factor activity
MP631_03940	COG0667	Aldo Keto reductase
MP631_03965	COG0631	protein serine/threonine phosphatase activity
MP631_04040	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MP631_04105	COG0463	Glycosyl transferase, family 2
MP631_04135	COG3387	PFAM Glycoside hydrolase 15-related
MP631_04165	COG0045	succinate-CoA ligase (ADP-forming) activity
MP631_04165	COG1042	CoA-binding domain protein
MP631_04165	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MP631_04175	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MP631_04180	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MP631_04200	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MP631_04225	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MP631_04230	COG0842	Transport permease protein
MP631_04235	COG1131	(ABC) transporter
MP631_04240	COG0633	Ferredoxin
MP631_04240	COG0543	2 iron, 2 sulfur cluster binding
MP631_04265	COG1476	TRANSCRIPTIONal
MP631_04275	COG4555	ABC transporter
MP631_04365	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MP631_04395	COG3328	transposase activity
MP631_04435	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MP631_04465	COG3228	Belongs to the MtfA family
MP631_04475	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
MP631_04475	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
MP631_04495	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MP631_04535	COG3237	CsbD-like
MP631_04545	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MP631_04570	COG0697	spore germination
MP631_04595	COG1136	(ABC) transporter
MP631_04600	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MP631_04605	COG4585	Histidine kinase
MP631_04610	COG2197	response regulator
MP631_04640	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MP631_04645	COG1011	Hydrolase
MP631_04690	COG0642	Histidine kinase
MP631_04700	COG1090	epimerase
MP631_04735	COG1690	Belongs to the RtcB family
MP631_04760	COG4943	cyclic-guanylate-specific phosphodiesterase activity
MP631_04775	COG0606	chelatase, subunit chli
MP631_04790	COG3291	Pkd domain containing protein
MP631_04790	COG3525	Glycosyl hydrolase, family 20, catalytic domain
MP631_04810	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
MP631_04815	COG1166	arginine decarboxylase activity
MP631_04830	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
MP631_04830	COG2755	lipolytic protein G-D-S-L family
MP631_04835	COG4221	oxidoreductase activity
MP631_04855	COG2003	Belongs to the UPF0758 family
MP631_04860	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MP631_04865	COG0756	dUTP diphosphatase activity
MP631_04885	COG0463	Glycosyl transferase, family 2
MP631_04900	COG1475	DNA binding
MP631_04905	COG1192	Involved in chromosome partitioning
MP631_04915	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MP631_04920	COG0708	Exodeoxyribonuclease III
MP631_04925	COG2223	nitrite transmembrane transporter activity
MP631_04935	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
MP631_04940	COG0739	heme binding
MP631_04945	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MP631_04985	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
MP631_05000	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
MP631_05030	COG0109	protoheme IX farnesyltransferase activity
MP631_05045	COG0358	DNA primase activity
MP631_05050	COG1295	ribonuclease BN
MP631_05055	COG1610	YqeY-like protein
MP631_05070	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MP631_05075	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MP631_05095	COG3328	transposase activity
MP631_05115	COG0531	amino acid
MP631_05135	COG3023	N-Acetylmuramoyl-L-alanine amidase
MP631_05140	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
MP631_05180	COG5383	Protein conserved in bacteria
MP631_05200	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MP631_05205	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MP631_05210	COG1473	amidohydrolase
MP631_05215	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
MP631_05215	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
MP631_05220	COG1652	LysM domain
MP631_05255	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MP631_05260	COG3118	belongs to the thioredoxin family
MP631_05265	COG0513	Belongs to the DEAD box helicase family
MP631_05270	COG2884	Cell division ATP-binding protein ftsE
MP631_05275	COG2177	Part of the ABC transporter FtsEX involved in
MP631_05280	COG2201	protein-glutamate methylesterase activity
MP631_05285	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MP631_05290	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MP631_05300	COG1252	NADH dehydrogenase
MP631_05315	COG0625	glutathione transferase activity
MP631_05320	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MP631_05340	COG0534	Mate efflux family protein
MP631_05345	COG0616	signal peptide processing
MP631_05355	COG1028	Short-chain dehydrogenase reductase Sdr
MP631_05370	COG0009	L-threonylcarbamoyladenylate synthase
MP631_05395	COG0758	DNA mediated transformation
MP631_05400	COG1652	LysM domain
MP631_05405	COG0242	peptide deformylase activity
MP631_05410	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MP631_05460	COG1560	Kdo2-lipid A biosynthetic process
MP631_05465	COG1490	D-aminoacyl-tRNA deacylase activity
MP631_05470	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MP631_05490	COG1028	Short-chain dehydrogenase reductase Sdr
MP631_05620	COG3328	transposase activity
MP631_05630	COG1063	alcohol dehydrogenase
MP631_05670	COG1271	oxidase subunit
MP631_05725	COG3685	Protein conserved in bacteria
MP631_05740	COG2972	Histidine kinase
MP631_05770	COG3590	peptidase
MP631_05785	COG0667	Aldo Keto reductase
MP631_05795	COG0583	DNA-binding transcription factor activity
MP631_05805	COG3384	dioxygenase
MP631_05820	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
MP631_05825	COG0025	NhaP-type Na H and K H
MP631_05830	COG1131	(ABC) transporter
MP631_05835	COG0842	Transport permease protein
MP631_05900	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MP631_05920	COG2205	protein histidine kinase activity
MP631_05920	COG2202	Pas domain
MP631_05940	COG3328	transposase activity
MP631_05950	COG3039	Transposase
MP631_05975	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MP631_06010	COG1666	GTP binding
MP631_06015	COG0697	spore germination
MP631_06020	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MP631_06060	COG0508	dehydrogenase complex catalyzes the overall conversion of
MP631_06070	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MP631_06090	COG0356	it plays a direct role in the translocation of protons across the membrane
MP631_06105	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MP631_06110	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MP631_06115	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MP631_06120	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MP631_06125	COG0355	proton-transporting ATP synthase activity, rotational mechanism
MP631_06150	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MP631_06190	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MP631_06195	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
MP631_06230	COG2132	Multicopper oxidase
MP631_06255	COG4991	sh3 domain protein
MP631_06265	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
MP631_06270	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MP631_06285	COG1956	GAF domain-containing protein
MP631_06295	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
MP631_06305	COG0720	synthase
MP631_06310	COG0513	Belongs to the DEAD box helicase family
MP631_06320	COG0625	glutathione transferase activity
MP631_06350	COG0626	cystathionine gamma-synthase activity
MP631_06355	COG0438	transferase activity, transferring glycosyl groups
MP631_06385	COG0438	transferase activity, transferring glycosyl groups
MP631_06395	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
MP631_06400	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MP631_06430	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MP631_06445	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
MP631_06445	COG0546	phosphoglycolate phosphatase activity
MP631_06465	COG2086	electron transfer activity
MP631_06500	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MP631_06530	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
MP631_06530	COG3218	ABC-type transport auxiliary lipoprotein component
MP631_06535	COG1127	ABC transporter
MP631_06540	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MP631_06555	COG0442	prolyl-tRNA aminoacylation
MP631_06565	COG1183	phosphatidylcholine synthase activity
MP631_06595	COG3328	transposase activity
MP631_06605	COG1307	EDD domain protein, DegV family
MP631_06625	COG3791	Glutathione-dependent formaldehyde-activating
MP631_06655	COG2205	protein histidine kinase activity
MP631_06670	COG0218	Necessary for normal cell division and for the maintenance of normal septation
MP631_06685	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
MP631_06710	COG3328	transposase activity
MP631_06740	COG0402	S-adenosylhomocysteine deaminase activity
MP631_06745	COG3964	amidohydrolase
MP631_06760	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
MP631_06780	COG0436	Aminotransferase
MP631_06810	COG2211	Major facilitator Superfamily
MP631_06820	COG1028	Short-chain dehydrogenase reductase Sdr
MP631_06840	COG0642	Histidine kinase
MP631_06870	COG0583	DNA-binding transcription factor activity
MP631_06895	COG1301	dicarboxylic acid transport
MP631_06900	COG0280	phosphate acetyltransferase
MP631_06900	COG0281	malic enzyme
MP631_06925	COG1560	Kdo2-lipid A biosynthetic process
MP631_06940	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
MP631_06960	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MP631_06965	COG0066	3-isopropylmalate dehydratase activity
MP631_06970	COG0473	3-isopropylmalate dehydrogenase activity
MP631_06980	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MP631_07000	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MP631_07005	COG0405	Gamma-glutamyltransferase
MP631_07010	COG0840	transmembrane signaling receptor activity
MP631_07020	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
MP631_07030	COG3328	transposase activity
MP631_07045	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
MP631_07070	COG0563	adenylate kinase activity
MP631_07075	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
MP631_07085	COG3781	membrane
MP631_07095	COG0671	phosphoesterase, PA-phosphatase related
MP631_07105	COG1028	Short-chain dehydrogenase reductase Sdr
MP631_07110	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MP631_07115	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MP631_07150	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
MP631_07160	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
MP631_07185	COG1773	rubredoxin
MP631_07190	COG2912	Transglutaminase-like superfamily
MP631_07230	COG3079	Belongs to the UPF0149 family
MP631_07235	COG0006	proline dipeptidase activity
MP631_07245	COG0006	proline dipeptidase activity
MP631_07265	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MP631_07280	COG1561	YicC-like family, N-terminal region
MP631_07295	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MP631_07305	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MP631_07365	COG0714	Associated with various cellular activities
MP631_07385	COG2304	oxidoreductase activity
MP631_07395	COG1301	dicarboxylic acid transport
MP631_07400	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MP631_07425	COG1376	ErfK ybiS ycfS ynhG family protein
MP631_07450	COG1022	Amp-dependent synthetase and ligase
MP631_07475	COG0642	Histidine kinase
MP631_07495	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
MP631_07500	COG4149	molybdate abc transporter
MP631_07505	COG0725	ABC transporter, periplasmic molybdate-binding protein
MP631_07510	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MP631_07510	COG3453	Protein conserved in bacteria
MP631_07525	COG3047	cAMP biosynthetic process
MP631_07535	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
MP631_07565	COG0126	phosphoglycerate kinase activity
MP631_07575	COG0469	pyruvate kinase activity
MP631_07580	COG3588	fructose-bisphosphate aldolase
MP631_07585	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
MP631_07600	COG1648	precorrin-2 dehydrogenase activity
MP631_07600	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
MP631_07615	COG0784	Response regulator, receiver
MP631_07615	COG2198	Histidine kinase
MP631_07615	COG2205	protein histidine kinase activity
MP631_07635	COG0175	sulfate reduction
MP631_07655	COG0529	Catalyzes the synthesis of activated sulfate
MP631_07655	COG2895	sulfate adenylyltransferase (ATP) activity
MP631_07680	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MP631_07690	COG4948	Mandelate Racemase Muconate Lactonizing
MP631_07695	COG3250	beta-galactosidase activity
MP631_07705	COG1609	Transcriptional regulator
MP631_07715	COG1970	mechanosensitive ion channel activity
MP631_07740	COG0471	metal ion transport
MP631_07740	COG3273	potassium ion transport
MP631_07750	COG2022	thiamine diphosphate biosynthetic process
MP631_07795	COG3328	transposase activity
MP631_07815	COG2003	Belongs to the UPF0758 family
MP631_07850	COG0189	ligase activity
MP631_07885	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
MP631_07935	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MP631_07950	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MP631_07950	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
MP631_07960	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MP631_07965	COG0564	pseudouridine synthase activity
MP631_07980	COG3011	Protein conserved in bacteria
MP631_07985	COG0840	transmembrane signaling receptor activity
MP631_08010	COG1877	trehalose-phosphatase activity
MP631_08055	COG0542	response to heat
MP631_08085	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
MP631_08135	COG0019	diaminopimelate decarboxylase activity
MP631_08150	COG4264	IucA IucC family
MP631_08160	COG4772	TonB-dependent receptor
MP631_08185	COG4651	solute:proton antiporter activity
MP631_08185	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
MP631_08240	COG0657	acetylesterase activity
MP631_08240	COG2755	lipolytic protein G-D-S-L family
MP631_08260	COG0477	Major facilitator Superfamily
MP631_08275	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MP631_08290	COG0217	transcriptional regulatory protein
MP631_08295	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
MP631_08300	COG0632	four-way junction helicase activity
MP631_08305	COG3158	transport of potassium into the cell
MP631_08325	COG0824	Thioesterase
MP631_08335	COG0848	biopolymer transport protein
MP631_08345	COG0823	Involved in the tonB-independent uptake of proteins
MP631_08350	COG2885	chlorophyll binding
MP631_08370	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
MP631_08395	COG0840	transmembrane signaling receptor activity
MP631_08435	COG0514	ATP-dependent DNA helicase (RecQ)
MP631_08440	COG0783	Belongs to the Dps family
MP631_08455	COG3328	transposase activity
MP631_08465	COG0837	glucose binding
MP631_08480	COG0535	radical SAM domain protein
MP631_08485	COG0535	radical SAM domain protein
MP631_08490	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
MP631_08515	COG1215	transferase activity, transferring glycosyl groups
MP631_08520	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MP631_08540	COG1397	ADP-ribosylglycohydrolase
MP631_08550	COG0189	ligase activity
MP631_08565	COG0835	chemotaxis
MP631_08570	COG0840	transmembrane signaling receptor activity
MP631_08600	COG1446	asparaginase
MP631_08605	COG3142	Participates in the control of copper homeostasis
MP631_08640	COG3537	Alpha-1,2-mannosidase
MP631_08650	COG1472	Belongs to the glycosyl hydrolase 3 family
MP631_08665	COG3328	transposase activity
MP631_08700	COG1385	rRNA (uridine-N3-)-methyltransferase activity
MP631_08710	COG0494	nUDIX hydrolase
MP631_08720	COG3956	TIGRFAM MazG family protein
MP631_08725	COG1742	UPF0060 membrane protein
MP631_08730	COG0330	HflC and HflK could
MP631_08740	COG0404	The glycine cleavage system catalyzes the degradation of glycine
MP631_08745	COG0509	glycine decarboxylation via glycine cleavage system
MP631_08785	COG1960	acyl-CoA dehydrogenase activity
MP631_08795	COG1309	transcriptional regulator
MP631_08825	COG0516	GMP reductase activity
MP631_08825	COG0517	IMP dehydrogenase activity
MP631_08835	COG1272	protein, Hemolysin III
MP631_08840	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MP631_08845	COG0739	heme binding
MP631_08850	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MP631_08855	COG0626	cystathionine gamma-synthase activity
MP631_08870	COG1760	l-serine dehydratase
MP631_08890	COG2353	YceI-like domain
MP631_08895	COG2198	Histidine kinase
MP631_08895	COG0784	Response regulator, receiver
MP631_08895	COG2205	protein histidine kinase activity
MP631_08920	COG2814	Major facilitator Superfamily
MP631_08925	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
MP631_08935	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MP631_08945	COG0259	pyridoxamine-phosphate oxidase activity
MP631_08955	COG1842	Phage shock protein A
MP631_08980	COG0754	glutathionylspermidine amidase activity
MP631_09130	COG2951	lytic endotransglycosylase activity
MP631_09155	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MP631_09220	COG2239	Acts as a magnesium transporter
MP631_09235	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
MP631_09245	COG1660	Displays ATPase and GTPase activities
MP631_09255	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MP631_09275	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
MP631_09285	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
MP631_09295	COG0271	Belongs to the BolA IbaG family
MP631_09300	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MP631_09320	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MP631_09335	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
MP631_09375	COG1555	photosystem II stabilization
MP631_09385	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MP631_09395	COG3328	transposase activity
MP631_09420	COG3128	pkhd-type hydroxylase
MP631_09430	COG2146	nitrite reductase [NAD(P)H] activity
MP631_09435	COG0456	acetyltransferase
MP631_09445	COG0719	Fe-S assembly protein
MP631_09450	COG0396	ATPase activity
MP631_09455	COG0719	Fe-S assembly protein
MP631_09460	COG1959	2 iron, 2 sulfur cluster binding
MP631_09470	COG0693	protein deglycase activity
MP631_09490	COG0739	heme binding
MP631_09505	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MP631_09530	COG0519	Catalyzes the synthesis of GMP from XMP
MP631_09540	COG1678	Uncharacterized ACR, COG1678
MP631_09545	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MP631_09565	COG0384	phenazine biosynthesis protein PhzF
MP631_09570	COG0384	phenazine biosynthesis protein PhzF
MP631_09590	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MP631_09600	COG0142	geranyltranstransferase activity
MP631_09605	COG0629	single-stranded DNA binding
MP631_09620	COG2080	2 iron, 2 sulfur cluster binding
MP631_09625	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
MP631_09630	COG1529	Aldehyde oxidase and xanthine dehydrogenase
MP631_09675	COG2879	small protein
MP631_09680	COG1966	Carbon starvation protein
MP631_09685	COG1741	Belongs to the pirin family
MP631_09700	COG1741	Belongs to the pirin family
MP631_09710	COG1515	deoxyribonuclease V activity
MP631_09725	COG3590	peptidase
MP631_09740	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
MP631_09745	COG2202	Pas domain
MP631_09745	COG2200	EAL domain
MP631_09745	COG2199	diguanylate cyclase activity
MP631_09750	COG0835	chemotaxis
MP631_09755	COG0840	transmembrane signaling receptor activity
MP631_09770	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MP631_09785	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
MP631_09790	COG0745	RESPONSE REGULATOR receiver
MP631_09810	COG4452	Inner membrane protein CreD
MP631_09840	COG0735	belongs to the Fur family
MP631_09855	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MP631_09865	COG1309	transcriptional regulator
MP631_09875	COG2207	Transcriptional regulator
MP631_09895	COG0667	Aldo Keto reductase
MP631_10010	COG1595	DNA-templated transcription, initiation
MP631_10020	COG5001	Diguanylate cyclase
MP631_10020	COG5002	protein histidine kinase activity
MP631_10025	COG1187	pseudouridine synthase activity
MP631_10045	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
MP631_10055	COG0475	glutathione-regulated potassium exporter activity
MP631_10065	COG0745	RESPONSE REGULATOR receiver
MP631_10095	COG1132	(ABC) transporter
MP631_10145	COG2155	Conserved Protein
MP631_10170	COG3118	belongs to the thioredoxin family
MP631_10180	COG0495	leucyl-tRNA aminoacylation
MP631_10210	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MP631_10225	COG2968	Membrane
MP631_10230	COG0424	maF-like protein
MP631_10255	COG3028	Belongs to the UPF0307 family
MP631_10260	COG0312	modulator of DNA gyrase
MP631_10270	COG4104	PAAR repeat-containing protein
MP631_10280	COG1722	exodeoxyribonuclease VII activity
MP631_10295	COG1301	dicarboxylic acid transport
MP631_10300	COG4106	trans-aconitate 2-methyltransferase activity
MP631_10310	COG0791	NLP P60 protein
MP631_10325	COG2311	Membrane
MP631_10330	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MP631_10390	COG0489	protein tyrosine kinase activity
MP631_10395	COG0717	Belongs to the dCTP deaminase family
MP631_10420	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MP631_10425	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
MP631_10450	COG0433	COG0433 Predicted ATPase
MP631_10460	COG0688	phosphatidylethanolamine metabolic process
MP631_10470	COG2890	protein-(glutamine-N5) methyltransferase activity
MP631_10475	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MP631_10485	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MP631_10500	COG0101	tRNA pseudouridine synthase activity
MP631_10505	COG0135	phosphoribosylanthranilate isomerase activity
MP631_10525	COG0159	tryptophan synthase activity
MP631_10530	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MP631_10535	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MP631_10565	COG4221	oxidoreductase activity
MP631_10570	COG0149	triose-phosphate isomerase activity
MP631_10585	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MP631_10595	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MP631_10605	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
MP631_10610	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
MP631_10620	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
MP631_10625	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MP631_10650	COG1007	ATP synthesis coupled electron transport
MP631_10670	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MP631_10675	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MP631_10680	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MP631_10685	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MP631_10735	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
MP631_10745	COG2095	MarC family integral membrane protein
MP631_10890	COG3179	chitinase
MP631_11065	COG3505	Type IV secretory pathway VirD4
MP631_11085	COG2948	multi-organism process
MP631_11195	COG0742	ribosomal rna small subunit methyltransferase
MP631_11200	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MP631_11215	COG0405	Gamma-glutamyltransferase
MP631_11220	COG3291	Pkd domain containing protein
MP631_11225	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MP631_11265	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MP631_11275	COG1862	Preprotein translocase
MP631_11285	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MP631_11295	COG3328	transposase activity
MP631_11330	COG1105	Belongs to the carbohydrate kinase PfkB family
MP631_11340	COG1609	Transcriptional regulator
MP631_11350	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MP631_11360	COG2902	Dehydrogenase
MP631_11390	COG0840	transmembrane signaling receptor activity
MP631_11420	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MP631_11440	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
MP631_11445	COG0243	molybdopterin cofactor binding
MP631_11460	COG2703	oxygen carrier activity
MP631_11470	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MP631_11480	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
MP631_11495	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
MP631_11520	COG1176	ABC-type spermidine putrescine transport system, permease component I
MP631_11525	COG1177	transmembrane transport
MP631_11530	COG1012	belongs to the aldehyde dehydrogenase family
MP631_11545	COG4535	Mg2 and Co2 transporter CorC
MP631_11565	COG1702	phosphate starvation-inducible protein PhoH
MP631_11570	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MP631_11585	COG0741	lytic transglycosylase activity
MP631_11595	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
MP631_11600	COG2857	Cytochrome c1
MP631_11605	COG0625	glutathione transferase activity
MP631_11610	COG2969	positive regulation of protein catabolic process
MP631_11630	COG1201	RNA secondary structure unwinding
MP631_11695	COG1262	PFAM Formylglycine-generating sulfatase enzyme
MP631_11705	COG1570	exodeoxyribonuclease VII activity
MP631_11710	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MP631_11715	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MP631_11715	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
MP631_11720	COG0802	atpase or kinase
MP631_11730	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MP631_11775	COG2081	HI0933 family
MP631_11780	COG2081	HI0933 family
MP631_11785	COG4681	YaeQ
MP631_11795	COG0625	glutathione transferase activity
MP631_11820	COG0513	Belongs to the DEAD box helicase family
MP631_11825	COG0488	(ABC) transporter
MP631_11845	COG0483	inositol monophosphate 1-phosphatase activity
MP631_11860	COG5001	Diguanylate cyclase
MP631_11860	COG3300	MHYT domain
MP631_11865	COG1509	lysine 2,3-aminomutase activity
MP631_11870	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MP631_11880	COG0402	S-adenosylhomocysteine deaminase activity
MP631_11885	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
MP631_11915	COG3039	Transposase
MP631_11945	COG4302	ethanolamine ammonia-lyase activity
MP631_11970	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
MP631_11975	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
MP631_11995	COG2166	iron-sulfur cluster assembly
MP631_12010	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MP631_12015	COG0137	argininosuccinate synthase activity
MP631_12025	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MP631_12045	COG0165	Argininosuccinate lyase
MP631_12055	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MP631_12060	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MP631_12090	COG1294	oxidase, subunit
MP631_12105	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
MP631_12140	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
MP631_12160	COG4133	protoheme IX ABC transporter activity
MP631_12170	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MP631_12190	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MP631_12200	COG2350	Protein conserved in bacteria
MP631_12230	COG1175	transmembrane transport
MP631_12235	COG0395	ABC-type sugar transport system, permease component
MP631_12260	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MP631_12265	COG2957	Belongs to the agmatine deiminase family
MP631_12280	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
MP631_12285	COG0539	negative regulation of cytoplasmic translation
MP631_12290	COG0776	regulation of translation
MP631_12300	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
MP631_12305	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MP631_12315	COG1210	Utp--glucose-1-phosphate uridylyltransferase
MP631_12320	COG0475	glutathione-regulated potassium exporter activity
MP631_12320	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
MP631_12330	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MP631_12340	COG0518	GMP synthase (glutamine-hydrolyzing) activity
MP631_12340	COG0519	Catalyzes the synthesis of GMP from XMP
MP631_12355	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
MP631_12375	COG2801	Transposase and inactivated derivatives
MP631_12390	COG0604	alcohol dehydrogenase
MP631_12420	COG0583	DNA-binding transcription factor activity
MP631_12460	COG1335	isochorismatase
MP631_12510	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
MP631_12525	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
MP631_12540	COG1028	Short-chain dehydrogenase reductase Sdr
MP631_12545	COG1183	phosphatidylcholine synthase activity
MP631_12570	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MP631_12570	COG0723	plastoquinol--plastocyanin reductase activity
MP631_12580	COG2183	response to ionizing radiation
MP631_12650	COG0800	Aldolase
MP631_12670	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MP631_12680	COG0354	folic acid binding
MP631_12695	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
MP631_12710	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
MP631_12725	COG4591	ABC-type transport system involved in lipoprotein release permease component
MP631_12730	COG1136	(ABC) transporter
MP631_12745	COG0811	peptide transport
MP631_12760	COG1663	tetraacyldisaccharide 4'-kinase activity
MP631_12770	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MP631_12780	COG0322	excinuclease ABC activity
MP631_12785	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MP631_12810	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
MP631_12835	COG1054	Belongs to the UPF0176 family
MP631_12845	COG3039	Transposase
MP631_12860	COG3064	Membrane
MP631_12865	COG0428	transporter
MP631_12890	COG1309	transcriptional regulator
MP631_12915	COG3328	transposase activity
MP631_12925	COG0363	glucosamine-6-phosphate deaminase activity
MP631_12955	COG3328	transposase activity
MP631_12960	COG3039	Transposase
MP631_13025	COG4566	intracellular signal transduction
MP631_13040	COG5001	Diguanylate cyclase
MP631_13060	COG3685	Protein conserved in bacteria
MP631_13080	COG0243	molybdopterin cofactor binding
MP631_13090	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MP631_13095	COG2223	nitrite transmembrane transporter activity
MP631_13110	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
MP631_13110	COG1648	precorrin-2 dehydrogenase activity
MP631_13135	COG0746	molybdenum cofactor guanylyltransferase activity
MP631_13190	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
MP631_13195	COG0303	'Molybdopterin
MP631_13205	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MP631_13225	COG0820	rRNA (adenine-C2-)-methyltransferase activity
MP631_13250	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MP631_13255	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
MP631_13265	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
MP631_13280	COG0492	ferredoxin-NADP+ reductase activity
MP631_13325	COG2915	High frequency lysogenization protein hflD homolog
MP631_13355	COG5002	protein histidine kinase activity
MP631_13380	COG0835	chemotaxis
MP631_13380	COG0784	Response regulator, receiver
MP631_13390	COG1558	bacterial-type flagellum-dependent cell motility
MP631_13395	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
MP631_13405	COG4787	bacterial-type flagellum-dependent cell motility
MP631_13415	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
MP631_13435	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MP631_13440	COG3039	Transposase
MP631_13485	COG2201	protein-glutamate methylesterase activity
MP631_13505	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MP631_13510	COG1028	Short-chain dehydrogenase reductase Sdr
MP631_13550	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
MP631_13580	COG1677	Flagellar hook-basal body complex protein FliE
MP631_13635	COG3190	flagellar
MP631_13655	COG1684	flagellar biosynthetic protein fliR
MP631_13690	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MP631_13720	COG0784	Response regulator, receiver
MP631_13720	COG0643	Histidine kinase
MP631_13720	COG2198	Histidine kinase
MP631_13755	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
MP631_13760	COG1360	Flagellar Motor Protein
MP631_13765	COG1192	Involved in chromosome partitioning
MP631_13780	COG0745	RESPONSE REGULATOR receiver
MP631_13790	COG0840	transmembrane signaling receptor activity
MP631_13795	COG0840	transmembrane signaling receptor activity
MP631_13810	COG0840	transmembrane signaling receptor activity
MP631_13825	COG0840	transmembrane signaling receptor activity
MP631_13830	COG0840	transmembrane signaling receptor activity
MP631_13835	COG0840	transmembrane signaling receptor activity
MP631_13855	COG0840	transmembrane signaling receptor activity
MP631_13860	COG0840	transmembrane signaling receptor activity
MP631_13865	COG0840	transmembrane signaling receptor activity
MP631_13870	COG0840	transmembrane signaling receptor activity
MP631_13895	COG0840	transmembrane signaling receptor activity
MP631_13905	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
MP631_13910	COG2201	protein-glutamate methylesterase activity
MP631_13915	COG3920	Histidine kinase
MP631_13930	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MP631_13965	COG0318	PFAM AMP-dependent synthetase and ligase
MP631_13980	COG2205	protein histidine kinase activity
MP631_13980	COG0784	Response regulator, receiver
MP631_13980	COG2198	Histidine kinase
MP631_13990	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
MP631_13995	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MP631_14020	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
MP631_14025	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
MP631_14035	COG0505	Belongs to the CarA family
MP631_14045	COG2258	MOSC domain
MP631_14050	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MP631_14095	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MP631_14130	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MP631_14145	COG0531	amino acid
MP631_14150	COG0235	Class ii aldolase
MP631_14155	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
MP631_14180	COG0107	imidazoleglycerol-phosphate synthase activity
MP631_14185	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
MP631_14190	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MP631_14195	COG0131	Imidazoleglycerol-phosphate dehydratase
MP631_14195	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
MP631_14200	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MP631_14210	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
MP631_14220	COG0124	histidyl-tRNA synthetase
MP631_14225	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MP631_14265	COG3328	transposase activity
MP631_14310	COG0840	transmembrane signaling receptor activity
MP631_14320	COG3328	transposase activity
MP631_14420	COG0531	amino acid
MP631_14445	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MP631_14465	COG3938	Belongs to the proline racemase family
MP631_14515	COG0322	excinuclease ABC activity
MP631_14530	COG3040	lipid binding
MP631_14570	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MP631_14605	COG0438	transferase activity, transferring glycosyl groups
MP631_14615	COG0438	transferase activity, transferring glycosyl groups
MP631_14690	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MP631_14710	COG2211	Major facilitator Superfamily
MP631_14745	COG3328	transposase activity
MP631_14775	COG0167	dihydroorotate dehydrogenase activity
MP631_14780	COG0812	UDP-N-acetylmuramate dehydrogenase activity
MP631_14785	COG0697	spore germination
MP631_14800	COG0671	phosphoesterase, PA-phosphatase related
MP631_14815	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
MP631_14820	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
MP631_14835	COG1472	Belongs to the glycosyl hydrolase 3 family
MP631_14860	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
MP631_14865	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
MP631_14910	COG0860	N-Acetylmuramoyl-L-alanine amidase
MP631_14935	COG0477	Major facilitator Superfamily
MP631_14945	COG1070	Carbohydrate kinase
MP631_14990	COG0800	Aldolase
MP631_14995	COG4948	Mandelate Racemase Muconate Lactonizing
MP631_15005	COG3734	2-keto-3-deoxy-galactonokinase
MP631_15010	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
MP631_15035	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MP631_15055	COG0351	phosphomethylpyrimidine kinase
MP631_15100	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
MP631_15105	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MP631_15110	COG2137	regulation of response to DNA damage stimulus
MP631_15115	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MP631_15120	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MP631_15130	COG1546	Belongs to the CinA family
MP631_15135	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MP631_15145	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MP631_15150	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MP631_15160	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
MP631_15165	COG1534	Rna-binding protein
MP631_15170	COG3737	Protein of unknown function (DUF498/DUF598)
MP631_15180	COG1238	metal cluster binding
MP631_15190	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
MP631_15200	COG0585	pseudouridine synthase activity
MP631_15205	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
MP631_15220	COG0148	phosphopyruvate hydratase activity
MP631_15235	COG0504	CTP synthase activity
MP631_15260	COG0306	phosphate transporter
MP631_15325	COG2264	protein methyltransferase activity
MP631_15355	COG2244	polysaccharide biosynthetic process
MP631_15405	COG1595	DNA-templated transcription, initiation
MP631_15420	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
MP631_15440	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MP631_15460	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
MP631_15465	COG0784	Response regulator, receiver
MP631_15465	COG4191	Histidine kinase
MP631_15485	COG0840	transmembrane signaling receptor activity
MP631_15495	COG3328	transposase activity
MP631_15515	COG0583	DNA-binding transcription factor activity
MP631_15520	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MP631_15525	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MP631_15540	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
MP631_15545	COG0077	Prephenate dehydratase
MP631_15545	COG1605	Chorismate mutase
MP631_15560	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
MP631_15600	COG1228	amidohydrolase
MP631_15605	COG2986	histidine ammonia-lyase
MP631_15635	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
MP631_15645	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
MP631_15650	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MP631_15665	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MP631_15685	COG0359	binds to the 23S rRNA
MP631_15690	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MP631_15695	COG0360	Binds together with S18 to 16S ribosomal RNA
MP631_15700	COG0316	Belongs to the HesB IscA family
MP631_15705	COG0017	Asparaginyl-tRNA synthetase
MP631_15785	COG0288	reversible hydration of carbon dioxide
MP631_15790	COG0662	Cupin 2, conserved barrel domain protein
MP631_15800	COG3844	kynureninase activity
MP631_15805	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MP631_15835	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MP631_15840	COG0116	Belongs to the methyltransferase superfamily
MP631_15840	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
MP631_15895	COG1024	Enoyl-CoA hydratase
MP631_15905	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MP631_15910	COG0659	secondary active sulfate transmembrane transporter activity
MP631_15935	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
MP631_15945	COG0581	inorganic phosphate transmembrane transporter activity
MP631_15955	COG0704	Plays a role in the regulation of phosphate uptake
MP631_15965	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
MP631_15975	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MP631_15985	COG0557	exoribonuclease II activity
MP631_16000	COG1960	acyl-CoA dehydrogenase activity
MP631_16010	COG0646	methionine synthase
MP631_16010	COG1410	methionine synthase
MP631_16015	COG0646	methionine synthase
MP631_16015	COG1410	methionine synthase
MP631_16055	COG2900	Belongs to the SlyX family
MP631_16070	COG0386	Belongs to the glutathione peroxidase family
MP631_16075	COG1725	Transcriptional regulator
MP631_16080	COG1131	(ABC) transporter
MP631_16165	COG1132	(ABC) transporter
MP631_16170	COG0583	DNA-binding transcription factor activity
MP631_16200	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
MP631_16205	COG0484	heat shock protein binding
MP631_16215	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MP631_16235	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MP631_16250	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
MP631_16275	COG3706	GGDEF domain
MP631_16320	COG0583	DNA-binding transcription factor activity
MP631_16350	COG0367	asparagine synthase
MP631_16365	COG1960	acyl-CoA dehydrogenase activity
MP631_16380	COG0084	hydrolase, TatD family'
MP631_16385	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
MP631_16450	COG0339	signal peptide processing
MP631_16515	COG1566	PFAM secretion protein HlyD family protein
MP631_16550	COG3328	transposase activity
MP631_16610	COG0367	asparagine synthase
MP631_16620	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MP631_16625	COG1393	Belongs to the ArsC family
MP631_16680	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MP631_16695	COG0233	cytoplasmic translational termination
MP631_16700	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MP631_16705	COG0575	Belongs to the CDS family
MP631_16710	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
MP631_16715	COG0750	zinc metalloprotease
MP631_16730	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MP631_16735	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
MP631_16740	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MP631_16760	COG0825	malonyl-CoA metabolic process
MP631_16775	COG1981	membrane
MP631_16795	COG1695	Transcriptional regulator
MP631_16815	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
MP631_16825	COG2040	homocysteine
MP631_16830	COG0833	amino acid
MP631_16845	COG0346	lactoylglutathione lyase activity
MP631_16865	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MP631_16865	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MP631_16875	COG2878	Part of a membrane complex involved in electron transport
MP631_16890	COG1595	DNA-templated transcription, initiation
MP631_16915	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
MP631_16935	COG0251	oxidation-reduction process
MP631_16945	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MP631_16945	COG0392	lysyltransferase activity
MP631_16995	COG2824	Alkylphosphonate utilization operon protein PhnA
MP631_17005	COG1047	Peptidyl-prolyl cis-trans
MP631_17010	COG1077	Cell shape determining protein MreB Mrl
MP631_17025	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
MP631_17035	COG5487	UPF0391 membrane protein
MP631_17040	COG1451	nucleotide metabolic process
MP631_17060	COG0183	Belongs to the thiolase family
MP631_17095	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
MP631_17095	COG1793	dna ligase
MP631_17105	COG1793	dna ligase
MP631_17125	COG1278	Cold shock
MP631_17130	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
MP631_17135	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
MP631_17140	COG1472	Belongs to the glycosyl hydrolase 3 family
MP631_17150	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
MP631_17155	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
MP631_17160	COG2954	triphosphatase activity
MP631_17165	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MP631_17175	COG1381	Involved in DNA repair and RecF pathway recombination
MP631_17185	COG0571	ribonuclease III activity
MP631_17205	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MP631_17270	COG1960	acyl-CoA dehydrogenase activity
MP631_17290	COG3867	Arabinogalactan endo-beta-1,4-galactanase
MP631_17380	COG0534	Mate efflux family protein
MP631_17385	COG0335	large ribosomal subunit rRNA binding
MP631_17390	COG0336	Belongs to the RNA methyltransferase TrmD family
MP631_17395	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MP631_17400	COG0228	four-way junction DNA binding
MP631_17405	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MP631_17415	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MP631_17450	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
MP631_17460	COG2205	protein histidine kinase activity
MP631_17465	COG5507	3-demethylubiquinone-9 3-methyltransferase
MP631_17475	COG4771	TonB-dependent receptor
MP631_17510	COG1366	Belongs to the anti-sigma-factor antagonist family
MP631_17520	COG0326	Molecular chaperone. Has ATPase activity
MP631_17535	COG3152	Membrane
MP631_17550	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
MP631_17555	COG1845	cytochrome c oxidase, subunit III
MP631_17575	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
MP631_17580	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MP631_17595	COG0196	riboflavin kinase activity
MP631_17605	COG0268	Binds directly to 16S ribosomal RNA
MP631_17610	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MP631_17615	COG0211	Belongs to the bacterial ribosomal protein bL27 family
MP631_17620	COG0261	This protein binds to 23S rRNA in the presence of protein L20
MP631_17630	COG0824	Thioesterase
MP631_17645	COG1946	Acyl-CoA thioesterase
MP631_17655	COG1595	DNA-templated transcription, initiation
MP631_17670	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
MP631_17680	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MP631_17705	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
MP631_17720	COG2197	response regulator
MP631_17725	COG4585	Histidine kinase
MP631_17735	COG0850	regulation of cytokinetic process
MP631_17740	COG2894	cell division
MP631_17745	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
MP631_17755	COG0642	Histidine kinase
MP631_17760	COG0745	RESPONSE REGULATOR receiver
MP631_17825	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MP631_17825	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MP631_17835	COG0656	L-ascorbic acid biosynthetic process
MP631_17865	COG3328	transposase activity
MP631_17875	COG1917	Cupin 2, conserved barrel domain protein
MP631_17875	COG2207	Transcriptional regulator
MP631_17930	COG1297	OPT oligopeptide transporter protein
MP631_17965	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MP631_18000	COG2080	2 iron, 2 sulfur cluster binding
MP631_18050	COG0492	ferredoxin-NADP+ reductase activity
MP631_18075	COG3537	Alpha-1,2-mannosidase
MP631_18080	COG1028	Short-chain dehydrogenase reductase Sdr
MP631_18095	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
MP631_18145	COG1028	Short-chain dehydrogenase reductase Sdr
MP631_18160	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MP631_18170	COG0330	HflC and HflK could
MP631_18175	COG0330	HflC and HflK could
MP631_18205	COG4953	penicillin-binding protein 1C
MP631_18210	COG3852	Histidine kinase
MP631_18310	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MP631_18325	COG1028	Short-chain dehydrogenase reductase Sdr
MP631_18340	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MP631_18345	COG0333	Belongs to the bacterial ribosomal protein bL32 family
MP631_18350	COG1399	metal-binding, possibly nucleic acid-binding protein
MP631_18355	COG0424	maF-like protein
MP631_18365	COG0714	Associated with various cellular activities
MP631_18390	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MP631_18395	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MP631_18450	COG0270	DNA (cytosine-5-)-methyltransferase activity
MP631_18495	COG2003	Belongs to the UPF0758 family
MP631_18545	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
MP631_18555	COG4245	von Willebrand factor, type A
MP631_18560	COG4245	von Willebrand factor, type A
MP631_18615	COG0314	molybdopterin synthase activity
MP631_18625	COG0315	cyclic pyranopterin monophosphate synthase activity
MP631_18640	COG1234	tRNA 3'-trailer cleavage
MP631_18645	COG3642	lipopolysaccharide core region biosynthetic process
MP631_18650	COG0859	PFAM glycosyl transferase family 9
MP631_18670	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
MP631_18675	COG0328	RNA-DNA hybrid ribonuclease activity
MP631_18685	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MP631_18695	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MP631_18725	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MP631_18735	COG0544	peptidyl-prolyl cis-trans isomerase activity
MP631_18755	COG3328	transposase activity
MP631_18795	COG0473	3-isopropylmalate dehydrogenase activity
MP631_18825	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
MP631_18840	COG0671	phosphoesterase, PA-phosphatase related
MP631_18845	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MP631_18860	COG2833	Protein of unknown function (DUF455)
MP631_18880	COG0285	dihydrofolate synthase activity
MP631_18890	COG0406	alpha-ribazole phosphatase activity
MP631_18925	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
MP631_18930	COG4208	sulfate ABC transporter
MP631_18945	COG0156	8-amino-7-oxononanoate synthase activity
MP631_18970	COG3039	Transposase
MP631_18975	COG0604	alcohol dehydrogenase
MP631_18980	COG0446	pyridine nucleotide-disulphide oxidoreductase
MP631_18980	COG1902	pentaerythritol trinitrate reductase activity
MP631_18995	COG0625	glutathione transferase activity
MP631_19000	COG0039	L-malate dehydrogenase activity
MP631_19005	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MP631_19010	COG1217	gtp-binding protein TYPA
MP631_19050	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
MP631_19055	COG0203	ribosomal protein L17
MP631_19085	COG0200	Binds to the 23S rRNA
MP631_19090	COG1841	ribosomal large subunit assembly
MP631_19100	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MP631_19105	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MP631_19110	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MP631_19120	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MP631_19125	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MP631_19140	COG0255	Belongs to the universal ribosomal protein uL29 family
MP631_19150	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MP631_19160	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MP631_19165	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MP631_19170	COG0089	rRNA binding
MP631_19180	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MP631_19185	COG0051	transcription antitermination factor activity, RNA binding
MP631_19190	COG3328	transposase activity
MP631_19210	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MP631_19220	COG0049	tRNA binding
MP631_19225	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MP631_19230	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MP631_19245	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MP631_19250	COG0081	regulation of translation
MP631_19255	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MP631_19260	COG0250	Participates in transcription elongation, termination and antitermination
MP631_19275	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MP631_19295	COG0012	GTP binding
MP631_19300	COG0193	aminoacyl-tRNA hydrolase activity
MP631_19305	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
MP631_19310	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MP631_19325	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
MP631_19340	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MP631_19350	COG0521	Mo-molybdopterin cofactor biosynthetic process
MP631_19365	COG1254	Belongs to the acylphosphatase family
MP631_19370	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MP631_19410	COG1404	Belongs to the peptidase S8 family
MP631_19415	COG1404	Belongs to the peptidase S8 family
MP631_19475	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MP631_19475	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MP631_19505	COG3634	alkyl hydroperoxide reductase activity
MP631_19510	COG0583	DNA-binding transcription factor activity
MP631_19515	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
MP631_19520	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MP631_19535	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MP631_19570	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MP631_19580	COG0697	spore germination
MP631_19605	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
MP631_19615	COG3386	PFAM SMP-30 Gluconolaconase
MP631_19635	COG1024	Enoyl-CoA hydratase
MP631_19645	COG0318	PFAM AMP-dependent synthetase and ligase
MP631_19650	COG0583	DNA-binding transcription factor activity
MP631_19655	COG3384	dioxygenase
MP631_19685	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MP631_19690	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MP631_19700	COG2096	Adenosyltransferase
MP631_19705	COG0123	including yeast histone deacetylase and acetoin utilization protein
MP631_19715	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
MP631_19720	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MP631_19730	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
MP631_19735	COG2967	ApaG domain
MP631_19740	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
MP631_19755	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MP631_19760	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MP631_19770	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
MP631_19780	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
MP631_19805	COG4181	ATPase activity
MP631_19825	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
MP631_19830	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MP631_19860	COG0667	Aldo Keto reductase
MP631_19865	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MP631_19870	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MP631_19885	COG4106	trans-aconitate 2-methyltransferase activity
MP631_19895	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MP631_19935	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
MP631_19945	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
MP631_19985	COG0366	Alpha amylase catalytic
MP631_20000	COG3321	synthase
MP631_20000	COG1028	Short-chain dehydrogenase reductase Sdr
MP631_20000	COG0604	alcohol dehydrogenase
MP631_20010	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
MP631_20030	COG0739	heme binding
MP631_20040	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
MP631_20055	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
MP631_20060	COG1181	Belongs to the D-alanine--D-alanine ligase family
MP631_20065	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
MP631_20070	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MP631_20080	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MP631_20085	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
MP631_20090	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MP631_20100	COG3116	cell division
MP631_20145	COG0792	nuclease activity
MP631_20150	COG1988	membrane-bound metal-dependent
MP631_20155	COG0277	FAD linked oxidase domain protein
MP631_20170	COG2205	protein histidine kinase activity
MP631_20180	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
MP631_20185	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
MP631_20200	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
MP631_20205	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MP631_20210	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
MP631_20240	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MP631_20245	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MP631_20255	COG0488	(ABC) transporter
MP631_20260	COG0242	peptide deformylase activity
MP631_20290	COG1215	transferase activity, transferring glycosyl groups
MP631_20295	COG1215	transferase activity, transferring glycosyl groups
MP631_20340	COG3039	Transposase
MP631_20375	COG2188	Transcriptional regulator
MP631_20400	COG3166	PFAM Fimbrial assembly family protein
MP631_20405	COG3156	type II secretion system protein K
MP631_20410	COG4795	General secretion pathway protein
MP631_20415	COG2165	general secretion pathway protein
MP631_20420	COG4970	Tfp pilus assembly protein FimT
MP631_20425	COG2165	general secretion pathway protein
MP631_20430	COG1459	type II secretion system
MP631_20435	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MP631_20450	COG1404	Belongs to the peptidase S8 family
MP631_20475	COG4974	Belongs to the 'phage' integrase family
MP631_20490	COG0795	lipopolysaccharide-transporting ATPase activity
MP631_20500	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MP631_20515	COG0525	valine-tRNA ligase activity
MP631_20540	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
MP631_20545	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
MP631_20550	COG1609	Transcriptional regulator
MP631_20605	COG1459	type II secretion system
MP631_20660	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MP631_20670	COG0784	Response regulator, receiver
MP631_20675	COG4251	negative regulation of phosphorylation
MP631_20680	COG2823	Periplasmic or secreted lipoprotein
MP631_20685	COG0673	inositol 2-dehydrogenase activity
MP631_20690	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
MP631_20725	COG1051	belongs to the nudix hydrolase family
MP631_20725	COG1056	cytidyltransferase-related domain
MP631_20760	COG2921	Belongs to the UPF0250 family
MP631_20770	COG1686	Belongs to the peptidase S11 family
MP631_20775	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
MP631_20865	COG1077	Cell shape determining protein MreB Mrl
MP631_20870	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MP631_20885	COG3284	Transcriptional regulator
MP631_20935	COG3300	MHYT domain
MP631_20935	COG5001	Diguanylate cyclase
MP631_20940	COG2226	methyltransferase
MP631_20965	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MP631_20985	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MP631_21005	COG0436	Aminotransferase
MP631_21060	COG3275	phosphorelay sensor kinase activity
MP631_21070	COG2943	transferase activity, transferring hexosyl groups
MP631_21130	COG2201	protein-glutamate methylesterase activity
MP631_21135	COG2205	protein histidine kinase activity
MP631_21135	COG0784	Response regulator, receiver
MP631_21140	COG3039	Transposase
MP631_21155	COG5002	protein histidine kinase activity
MP631_21155	COG5001	Diguanylate cyclase
MP631_21155	COG3447	MASE1 domain protein
MP631_21200	COG0598	Magnesium transport protein CorA
MP631_21210	COG1113	amino acid transport
MP631_21230	COG0697	spore germination
MP631_21255	COG1959	2 iron, 2 sulfur cluster binding
MP631_21320	COG0435	Glutathione S-transferase
MP631_21330	COG4221	oxidoreductase activity
MP631_21360	COG4221	oxidoreductase activity
MP631_21370	COG3328	transposase activity
MP631_21435	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
MP631_21460	COG3052	prosthetic group binding
MP631_21495	COG2353	YceI-like domain
MP631_21500	COG0778	Nitroreductase
MP631_21520	COG3039	Transposase
MP631_21540	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
MP631_21545	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
MP631_21570	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MP631_21575	COG3550	peptidyl-serine autophosphorylation
MP631_21590	COG0459	protein refolding
MP631_21625	COG0511	ligase activity, forming carbon-carbon bonds
MP631_21635	COG0439	Biotin carboxylase
MP631_21650	COG2264	protein methyltransferase activity
MP631_21670	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
MP631_21675	COG4589	Belongs to the CDS family
MP631_21705	COG2267	carboxylic ester hydrolase activity
MP631_21710	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MP631_21715	COG0138	bifunctional purine biosynthesis protein purh
MP631_21725	COG0151	Belongs to the GarS family
MP631_21735	COG1289	transmembrane transporter activity
MP631_21740	COG2814	Major facilitator Superfamily
MP631_21750	COG2814	Major facilitator Superfamily
MP631_21765	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
MP631_21780	COG0316	Belongs to the HesB IscA family
MP631_21820	COG1051	belongs to the nudix hydrolase family
MP631_21835	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
MP631_21845	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
MP631_21870	COG0134	indole-3-glycerol-phosphate synthase activity
MP631_21875	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MP631_21905	COG1597	lipid kinase activity
MP631_21925	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
MP631_21950	COG3179	chitinase
MP631_21975	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
MP631_21975	COG2111	Na H antiporter
MP631_21980	COG1006	Multisubunit Na H antiporter MnhC subunit
MP631_21995	COG2212	antiporter activity
MP631_22000	COG1320	monovalent cation:proton antiporter activity
MP631_22030	COG2852	Protein conserved in bacteria
MP631_22055	COG3483	tryptophan 2,3-dioxygenase activity
MP631_22065	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
MP631_22080	COG0508	dehydrogenase complex catalyzes the overall conversion of
MP631_22085	COG0513	Belongs to the DEAD box helicase family
MP631_22095	COG1028	Short-chain dehydrogenase reductase Sdr
MP631_22100	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MP631_22150	COG3328	transposase activity
MP631_22170	COG1858	cytochrome C peroxidase
MP631_22180	COG0702	epimerase
MP631_22205	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MP631_22210	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MP631_22220	COG0297	glycogen (starch) synthase activity
MP631_22230	COG2354	Protein conserved in bacteria
MP631_22235	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
MP631_22240	COG1368	sulfuric ester hydrolase activity
MP631_22390	COG3039	Transposase
MP631_22415	COG1040	competence protein
MP631_22420	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
MP631_22425	COG0156	8-amino-7-oxononanoate synthase activity
MP631_22435	COG2267	carboxylic ester hydrolase activity
MP631_22465	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MP631_22495	COG1414	Transcriptional regulator
MP631_22505	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MP631_22510	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MP631_22520	COG3485	protocatechuate 3,4-dioxygenase
MP631_22525	COG3485	protocatechuate 3,4-dioxygenase
MP631_22565	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
MP631_22570	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MP631_22580	COG3328	transposase activity
MP631_22630	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
MP631_22705	COG0702	epimerase
MP631_22740	COG0583	DNA-binding transcription factor activity
MP631_22745	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MP631_22770	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MP631_22800	COG1902	pentaerythritol trinitrate reductase activity
MP631_22805	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
MP631_22870	COG3328	transposase activity
MP631_23005	COG0489	protein tyrosine kinase activity
MP631_23080	COG4962	Type ii secretion system protein e
MP631_23095	COG3451	type IV secretory pathway VirB4
MP631_23105	COG3451	type IV secretory pathway VirB4
MP631_23115	COG3846	protein secretion by the type IV secretion system
MP631_23155	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MP631_23170	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MP631_23190	COG1487	ribonuclease activity
MP631_23195	COG4691	Plasmid stability protein
MP631_23385	COG0489	protein tyrosine kinase activity
MP631_23445	COG3328	transposase activity
MP631_23520	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MP631_23650	COG3039	Transposase