locus-tag	class	description
OM952_00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
OM952_00020	COG0187	DNA topoisomerase II activity
OM952_00030	COG0501	Belongs to the peptidase M48B family
OM952_00075	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
OM952_00085	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OM952_00130	COG0793	Belongs to the peptidase S41A family
OM952_00135	COG4942	peptidase
OM952_00145	COG2234	aminopeptidase activity
OM952_00155	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
OM952_00160	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
OM952_00170	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
OM952_00175	COG1064	alcohol dehydrogenase
OM952_00190	COG0493	'glutamate synthase
OM952_00195	COG0069	glutamate synthase activity
OM952_00195	COG0070	glutamate synthase
OM952_00195	COG0067	glutamate synthase
OM952_00285	COG1111	helicase
OM952_00285	COG1205	dead DEAH box helicase
OM952_00290	COG1272	protein, Hemolysin III
OM952_00310	COG0300	oxidoreductase activity
OM952_00315	COG1028	Short-chain dehydrogenase reductase Sdr
OM952_00340	COG2249	NAD(P)H dehydrogenase (quinone) activity
OM952_00350	COG3039	Transposase
OM952_00365	COG3039	Transposase
OM952_00375	COG3237	CsbD-like
OM952_00425	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OM952_00430	COG0477	Major facilitator Superfamily
OM952_00475	COG0714	Associated with various cellular activities
OM952_00515	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
OM952_00525	COG4772	TonB-dependent receptor
OM952_00550	COG1304	FMN binding
OM952_00555	COG1755	Isoprenylcysteine carboxyl methyltransferase
OM952_00560	COG4585	Histidine kinase
OM952_00565	COG2197	response regulator
OM952_00590	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
OM952_00595	COG3039	Transposase
OM952_00660	COG3328	transposase activity
OM952_00685	COG3039	Transposase
OM952_00690	COG3039	Transposase
OM952_00705	COG0366	Alpha amylase catalytic
OM952_00710	COG0366	Alpha amylase catalytic
OM952_00715	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
OM952_00735	COG0657	acetylesterase activity
OM952_00735	COG2755	lipolytic protein G-D-S-L family
OM952_00745	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
OM952_00760	COG3507	Belongs to the glycosyl hydrolase 43 family
OM952_00765	COG1609	Transcriptional regulator
OM952_00770	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
OM952_00775	COG1028	Short-chain dehydrogenase reductase Sdr
OM952_00785	COG2755	lipolytic protein G-D-S-L family
OM952_00795	COG3186	Phenylalanine-4-hydroxylase
OM952_00800	COG1522	sequence-specific DNA binding
OM952_00810	COG1752	Esterase of the alpha-beta hydrolase superfamily
OM952_00820	COG1119	ATPase activity
OM952_00835	COG0517	IMP dehydrogenase activity
OM952_00835	COG1125	glycine betaine transport
OM952_00850	COG1262	PFAM Formylglycine-generating sulfatase enzyme
OM952_00880	COG0489	protein tyrosine kinase activity
OM952_00885	COG2062	phosphohistidine phosphatase, SixA
OM952_00895	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OM952_00935	COG1968	undecaprenyl-diphosphatase activity
OM952_00940	COG0174	glutamine synthetase
OM952_00945	COG0347	Belongs to the P(II) protein family
OM952_00950	COG0004	ammonium transporteR
OM952_00955	COG3852	Histidine kinase
OM952_00960	COG2204	response regulator
OM952_00965	COG2032	superoxide dismutase activity
OM952_00970	COG2032	superoxide dismutase activity
OM952_00985	COG0183	Belongs to the thiolase family
OM952_01020	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OM952_01025	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
OM952_01030	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
OM952_01055	COG2205	protein histidine kinase activity
OM952_01080	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
OM952_01095	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OM952_01100	COG3177	Filamentation induced by cAMP protein fic
OM952_01105	COG0596	Alpha beta hydrolase
OM952_01110	COG0727	PFAM Uncharacterised protein family (UPF0153)
OM952_01115	COG0318	PFAM AMP-dependent synthetase and ligase
OM952_01120	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OM952_01135	COG1181	Belongs to the D-alanine--D-alanine ligase family
OM952_01145	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
OM952_01155	COG0564	pseudouridine synthase activity
OM952_01175	COG1446	asparaginase
OM952_01180	COG0339	signal peptide processing
OM952_01215	COG0475	glutathione-regulated potassium exporter activity
OM952_01225	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
OM952_01230	COG2224	Isocitrate lyase
OM952_01250	COG3039	Transposase
OM952_01270	COG4770	biotin carboxylase activity
OM952_01275	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
OM952_01280	COG1960	acyl-CoA dehydrogenase activity
OM952_01345	COG0697	spore germination
OM952_01355	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
OM952_01360	COG1846	Transcriptional regulator
OM952_01365	COG1764	response to oxidative stress
OM952_01385	COG2130	NADP-dependent
OM952_01400	COG1187	pseudouridine synthase activity
OM952_01410	COG1643	Atp-dependent helicase
OM952_01415	COG4807	Protein conserved in bacteria
OM952_01425	COG2072	flavoprotein involved in K transport
OM952_01445	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
OM952_01455	COG0583	DNA-binding transcription factor activity
OM952_01490	COG2252	PERMEase
OM952_01510	COG0084	hydrolase, TatD family'
OM952_01525	COG0583	DNA-binding transcription factor activity
OM952_01530	COG2814	Major facilitator Superfamily
OM952_01545	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
OM952_01550	COG1902	pentaerythritol trinitrate reductase activity
OM952_01570	COG0745	RESPONSE REGULATOR receiver
OM952_01575	COG2205	protein histidine kinase activity
OM952_01580	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OM952_01605	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
OM952_01610	COG0583	DNA-binding transcription factor activity
OM952_01645	COG0702	epimerase
OM952_01650	COG1733	regulation of RNA biosynthetic process
OM952_01665	COG3328	transposase activity
OM952_01705	COG0129	dihydroxy-acid dehydratase activity
OM952_01720	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
OM952_01775	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
OM952_01780	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
OM952_01805	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
OM952_01820	COG3485	protocatechuate 3,4-dioxygenase
OM952_01825	COG3485	protocatechuate 3,4-dioxygenase
OM952_01835	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OM952_01840	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OM952_01850	COG1414	Transcriptional regulator
OM952_01860	COG0657	acetylesterase activity
OM952_01870	COG0445	tRNA wobble uridine modification
OM952_01880	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
OM952_01910	COG2267	carboxylic ester hydrolase activity
OM952_01920	COG0156	8-amino-7-oxononanoate synthase activity
OM952_01925	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
OM952_01930	COG1040	competence protein
OM952_01935	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
OM952_01955	COG3039	Transposase
OM952_01960	COG3328	transposase activity
OM952_02025	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
OM952_02095	COG1511	domain protein
OM952_02095	COG3264	Mechanosensitive ion channel
OM952_02100	COG1368	sulfuric ester hydrolase activity
OM952_02105	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
OM952_02110	COG2354	Protein conserved in bacteria
OM952_02120	COG0297	glycogen (starch) synthase activity
OM952_02125	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
OM952_02130	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
OM952_02155	COG0702	epimerase
OM952_02165	COG1858	cytochrome C peroxidase
OM952_02185	COG3328	transposase activity
OM952_02195	COG3039	Transposase
OM952_02205	COG1028	Short-chain dehydrogenase reductase Sdr
OM952_02240	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OM952_02245	COG1028	Short-chain dehydrogenase reductase Sdr
OM952_02255	COG0513	Belongs to the DEAD box helicase family
OM952_02260	COG0508	dehydrogenase complex catalyzes the overall conversion of
OM952_02275	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
OM952_02285	COG3483	tryptophan 2,3-dioxygenase activity
OM952_02290	COG3104	oligopeptide transport
OM952_02310	COG2852	Protein conserved in bacteria
OM952_02315	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
OM952_02335	COG1320	monovalent cation:proton antiporter activity
OM952_02340	COG2212	antiporter activity
OM952_02350	COG0651	ATP synthesis coupled electron transport
OM952_02355	COG1006	Multisubunit Na H antiporter MnhC subunit
OM952_02360	COG2111	Na H antiporter
OM952_02360	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
OM952_02380	COG3179	chitinase
OM952_02400	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
OM952_02405	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
OM952_02425	COG1597	lipid kinase activity
OM952_02455	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
OM952_02460	COG0134	indole-3-glycerol-phosphate synthase activity
OM952_02470	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OM952_02475	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
OM952_02485	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
OM952_02495	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
OM952_02510	COG1051	belongs to the nudix hydrolase family
OM952_02550	COG0316	Belongs to the HesB IscA family
OM952_02565	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
OM952_02580	COG2814	Major facilitator Superfamily
OM952_02590	COG2814	Major facilitator Superfamily
OM952_02595	COG1289	transmembrane transporter activity
OM952_02605	COG0151	Belongs to the GarS family
OM952_02615	COG0138	bifunctional purine biosynthesis protein purh
OM952_02620	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
OM952_02625	COG2267	carboxylic ester hydrolase activity
OM952_02630	COG2453	phosphatase
OM952_02630	COG0671	phosphoesterase, PA-phosphatase related
OM952_02655	COG4589	Belongs to the CDS family
OM952_02660	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
OM952_02680	COG2264	protein methyltransferase activity
OM952_02695	COG0439	Biotin carboxylase
OM952_02705	COG0511	ligase activity, forming carbon-carbon bonds
OM952_02710	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
OM952_02720	COG1324	tolerance protein
OM952_02740	COG0459	protein refolding
OM952_02755	COG3550	peptidyl-serine autophosphorylation
OM952_02760	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
OM952_02775	COG3386	PFAM SMP-30 Gluconolaconase
OM952_02785	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
OM952_02790	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
OM952_02810	COG3039	Transposase
OM952_02830	COG0778	Nitroreductase
OM952_02835	COG2353	YceI-like domain
OM952_02870	COG3052	prosthetic group binding
OM952_02895	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
OM952_02905	COG1802	Transcriptional regulator
OM952_02960	COG3328	transposase activity
OM952_02970	COG4221	oxidoreductase activity
OM952_02980	COG3039	Transposase
OM952_03010	COG4221	oxidoreductase activity
OM952_03020	COG0435	Glutathione S-transferase
OM952_03085	COG1959	2 iron, 2 sulfur cluster binding
OM952_03110	COG0697	spore germination
OM952_03115	COG4305	rare lipoprotein A
OM952_03120	COG5297	Belongs to the glycosyl hydrolase family 6
OM952_03130	COG1113	amino acid transport
OM952_03140	COG0598	Magnesium transport protein CorA
OM952_03185	COG5002	protein histidine kinase activity
OM952_03185	COG5001	Diguanylate cyclase
OM952_03185	COG3447	MASE1 domain protein
OM952_03195	COG0784	Response regulator, receiver
OM952_03195	COG2205	protein histidine kinase activity
OM952_03225	COG2943	transferase activity, transferring hexosyl groups
OM952_03235	COG3275	phosphorelay sensor kinase activity
OM952_03245	COG0181	hydroxymethylbilane synthase activity
OM952_03280	COG1505	serine-type exopeptidase activity
OM952_03290	COG0436	Aminotransferase
OM952_03300	COG2832	Protein of unknown function (DUF454)
OM952_03310	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
OM952_03320	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
OM952_03325	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
OM952_03330	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
OM952_03355	COG2226	methyltransferase
OM952_03360	COG3300	MHYT domain
OM952_03360	COG5001	Diguanylate cyclase
OM952_03365	COG0308	aminopeptidase N
OM952_03410	COG3284	Transcriptional regulator
OM952_03425	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OM952_03430	COG1077	Cell shape determining protein MreB Mrl
OM952_03435	COG1792	Involved in formation and maintenance of cell shape
OM952_03450	COG0772	Belongs to the SEDS family
OM952_03465	COG3039	Transposase
OM952_03500	COG2951	lytic endotransglycosylase activity
OM952_03505	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
OM952_03510	COG1686	Belongs to the peptidase S11 family
OM952_03520	COG2921	Belongs to the UPF0250 family
OM952_03525	COG0321	lipoyl(octanoyl) transferase activity
OM952_03530	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
OM952_03555	COG1051	belongs to the nudix hydrolase family
OM952_03555	COG1056	cytidyltransferase-related domain
OM952_03590	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
OM952_03595	COG0673	inositol 2-dehydrogenase activity
OM952_03600	COG2823	Periplasmic or secreted lipoprotein
OM952_03605	COG4251	negative regulation of phosphorylation
OM952_03610	COG0784	Response regulator, receiver
OM952_03615	COG4191	Histidine kinase
OM952_03620	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
OM952_03675	COG1459	type II secretion system
OM952_03720	COG2188	Transcriptional regulator
OM952_03730	COG1609	Transcriptional regulator
OM952_03735	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
OM952_03740	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
OM952_03750	COG0617	tRNA 3'-terminal CCA addition
OM952_03765	COG0525	valine-tRNA ligase activity
OM952_03780	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
OM952_03790	COG0795	lipopolysaccharide-transporting ATPase activity
OM952_03805	COG4974	Belongs to the 'phage' integrase family
OM952_03815	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
OM952_03820	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
OM952_03820	COG0047	phosphoribosylformylglycinamidine synthase activity
OM952_03825	COG5295	Hep Hag repeat protein
OM952_03830	COG1404	Belongs to the peptidase S8 family
OM952_03835	COG5295	Hep Hag repeat protein
OM952_03840	COG1404	Belongs to the peptidase S8 family
OM952_03845	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
OM952_03850	COG1459	type II secretion system
OM952_03855	COG2165	general secretion pathway protein
OM952_03860	COG4970	Tfp pilus assembly protein FimT
OM952_03865	COG2165	general secretion pathway protein
OM952_03870	COG4795	General secretion pathway protein
OM952_03875	COG3156	type II secretion system protein K
OM952_03880	COG3166	PFAM Fimbrial assembly family protein
OM952_03895	COG1450	Type ii and iii secretion system protein
OM952_03905	COG2188	Transcriptional regulator
OM952_03975	COG1215	transferase activity, transferring glycosyl groups
OM952_03980	COG1215	transferase activity, transferring glycosyl groups
OM952_03985	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
OM952_04010	COG0242	peptide deformylase activity
OM952_04015	COG0488	(ABC) transporter
OM952_04025	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
OM952_04030	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
OM952_04040	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OM952_04040	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OM952_04060	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
OM952_04065	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
OM952_04070	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
OM952_04085	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
OM952_04090	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
OM952_04100	COG2205	protein histidine kinase activity
OM952_04105	COG0745	RESPONSE REGULATOR receiver
OM952_04115	COG0277	FAD linked oxidase domain protein
OM952_04120	COG1988	membrane-bound metal-dependent
OM952_04125	COG0792	nuclease activity
OM952_04165	COG3116	cell division
OM952_04175	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
OM952_04180	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
OM952_04185	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
OM952_04195	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
OM952_04200	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
OM952_04205	COG1181	Belongs to the D-alanine--D-alanine ligase family
OM952_04210	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
OM952_04225	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
OM952_04235	COG0739	heme binding
OM952_04240	COG0653	protein targeting
OM952_04245	COG0494	nUDIX hydrolase
OM952_04255	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
OM952_04265	COG0604	alcohol dehydrogenase
OM952_04265	COG1028	Short-chain dehydrogenase reductase Sdr
OM952_04265	COG3321	synthase
OM952_04280	COG0366	Alpha amylase catalytic
OM952_04315	COG2226	methyltransferase
OM952_04320	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
OM952_04330	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
OM952_04370	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
OM952_04380	COG4106	trans-aconitate 2-methyltransferase activity
OM952_04385	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OM952_04400	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OM952_04405	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
OM952_04410	COG0667	Aldo Keto reductase
OM952_04420	COG4771	TonB-dependent receptor
OM952_04440	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OM952_04445	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
OM952_04455	COG2175	clavaminate synthase activity
OM952_04465	COG4181	ATPase activity
OM952_04480	COG0642	Histidine kinase
OM952_04490	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
OM952_04500	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
OM952_04510	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
OM952_04515	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
OM952_04530	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
OM952_04535	COG2967	ApaG domain
OM952_04540	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
OM952_04545	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
OM952_04550	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
OM952_04555	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
OM952_04565	COG0123	including yeast histone deacetylase and acetoin utilization protein
OM952_04570	COG2096	Adenosyltransferase
OM952_04580	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OM952_04585	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OM952_04615	COG3384	dioxygenase
OM952_04620	COG0583	DNA-binding transcription factor activity
OM952_04625	COG0318	PFAM AMP-dependent synthetase and ligase
OM952_04635	COG1024	Enoyl-CoA hydratase
OM952_04655	COG3386	PFAM SMP-30 Gluconolaconase
OM952_04665	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
OM952_04690	COG0697	spore germination
OM952_04700	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OM952_04725	COG2197	response regulator
OM952_04735	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OM952_04750	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
OM952_04755	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
OM952_04760	COG0583	DNA-binding transcription factor activity
OM952_04765	COG3634	alkyl hydroperoxide reductase activity
OM952_04775	COG2890	protein-(glutamine-N5) methyltransferase activity
OM952_04795	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OM952_04795	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OM952_04850	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
OM952_04855	COG1404	Belongs to the peptidase S8 family
OM952_04860	COG1404	Belongs to the peptidase S8 family
OM952_04865	COG1404	Belongs to the peptidase S8 family
OM952_04870	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
OM952_04895	COG1295	ribonuclease BN
OM952_04900	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OM952_04905	COG1254	Belongs to the acylphosphatase family
OM952_04920	COG0521	Mo-molybdopterin cofactor biosynthetic process
OM952_04930	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
OM952_04935	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
OM952_04945	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
OM952_04950	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
OM952_04960	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
OM952_04965	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
OM952_04970	COG0193	aminoacyl-tRNA hydrolase activity
OM952_04975	COG0012	GTP binding
OM952_04995	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
OM952_05010	COG0250	Participates in transcription elongation, termination and antitermination
OM952_05015	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
OM952_05020	COG0081	regulation of translation
OM952_05025	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
OM952_05035	COG0085	RNA polymerase activity
OM952_05040	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
OM952_05045	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
OM952_05050	COG0049	tRNA binding
OM952_05055	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
OM952_05060	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
OM952_05080	COG3328	transposase activity
OM952_05085	COG0051	transcription antitermination factor activity, RNA binding
OM952_05090	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
OM952_05095	COG0088	Forms part of the polypeptide exit tunnel
OM952_05100	COG0089	rRNA binding
OM952_05105	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
OM952_05110	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
OM952_05120	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
OM952_05125	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
OM952_05130	COG0255	Belongs to the universal ribosomal protein uL29 family
OM952_05135	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
OM952_05145	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
OM952_05150	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
OM952_05160	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
OM952_05165	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
OM952_05170	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
OM952_05180	COG1841	ribosomal large subunit assembly
OM952_05185	COG0200	Binds to the 23S rRNA
OM952_05190	COG0201	protein transport
OM952_05215	COG0203	ribosomal protein L17
OM952_05220	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
OM952_05240	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
OM952_05250	COG0154	amidase activity
OM952_05260	COG1217	gtp-binding protein TYPA
OM952_05265	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
OM952_05270	COG0039	L-malate dehydrogenase activity
OM952_05275	COG0625	glutathione transferase activity
OM952_05290	COG0446	pyridine nucleotide-disulphide oxidoreductase
OM952_05290	COG1902	pentaerythritol trinitrate reductase activity
OM952_05295	COG0604	alcohol dehydrogenase
OM952_05300	COG3328	transposase activity
OM952_05305	COG3039	Transposase
OM952_05310	COG2885	chlorophyll binding
OM952_05330	COG0156	8-amino-7-oxononanoate synthase activity
OM952_05335	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
OM952_05340	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
OM952_05345	COG4208	sulfate ABC transporter
OM952_05350	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
OM952_05365	COG3328	transposase activity
OM952_05390	COG0406	alpha-ribazole phosphatase activity
OM952_05400	COG0285	dihydrofolate synthase activity
OM952_05420	COG2833	Protein of unknown function (DUF455)
OM952_05435	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
OM952_05440	COG0671	phosphoesterase, PA-phosphatase related
OM952_05445	COG0438	transferase activity, transferring glycosyl groups
OM952_05455	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
OM952_05470	COG4783	chaperone-mediated protein folding
OM952_05485	COG0473	3-isopropylmalate dehydrogenase activity
OM952_05525	COG3328	transposase activity
OM952_05540	COG0544	peptidyl-prolyl cis-trans isomerase activity
OM952_05550	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
OM952_05580	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
OM952_05590	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OM952_05600	COG0328	RNA-DNA hybrid ribonuclease activity
OM952_05605	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
OM952_05610	COG0631	protein serine/threonine phosphatase activity
OM952_05630	COG0859	PFAM glycosyl transferase family 9
OM952_05635	COG3642	lipopolysaccharide core region biosynthetic process
OM952_05640	COG1234	tRNA 3'-trailer cleavage
OM952_05645	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
OM952_05655	COG0315	cyclic pyranopterin monophosphate synthase activity
OM952_05660	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
OM952_05665	COG0314	molybdopterin synthase activity
OM952_05685	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
OM952_05690	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
OM952_05695	COG0537	adenosine 5'-monophosphoramidase activity
OM952_05715	COG0714	Associated with various cellular activities
OM952_05725	COG0424	maF-like protein
OM952_05730	COG1399	metal-binding, possibly nucleic acid-binding protein
OM952_05735	COG0333	Belongs to the bacterial ribosomal protein bL32 family
OM952_05740	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OM952_05755	COG1028	Short-chain dehydrogenase reductase Sdr
OM952_05770	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
OM952_05775	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
OM952_05805	COG3829	transcription factor binding
OM952_05850	COG2373	Large extracellular alpha-helical protein
OM952_05870	COG3852	Histidine kinase
OM952_05875	COG4953	penicillin-binding protein 1C
OM952_05885	COG0678	peroxiredoxin activity
OM952_05905	COG0330	HflC and HflK could
OM952_05910	COG0330	HflC and HflK could
OM952_05920	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
OM952_05925	COG0308	aminopeptidase N
OM952_05935	COG1028	Short-chain dehydrogenase reductase Sdr
OM952_05940	COG1309	transcriptional regulator
OM952_05960	COG3328	transposase activity
OM952_05990	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
OM952_06000	COG3387	PFAM Glycoside hydrolase 15-related
OM952_06005	COG1028	Short-chain dehydrogenase reductase Sdr
OM952_06010	COG3537	Alpha-1,2-mannosidase
OM952_06035	COG0492	ferredoxin-NADP+ reductase activity
OM952_06065	COG1529	Aldehyde oxidase and xanthine dehydrogenase
OM952_06070	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
OM952_06075	COG2080	2 iron, 2 sulfur cluster binding
OM952_06110	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
OM952_06125	COG0587	DNA-directed DNA polymerase activity
OM952_06145	COG1297	OPT oligopeptide transporter protein
OM952_06170	COG0823	Involved in the tonB-independent uptake of proteins
OM952_06170	COG1506	peptidase
OM952_06205	COG1917	Cupin 2, conserved barrel domain protein
OM952_06205	COG2207	Transcriptional regulator
OM952_06215	COG3328	transposase activity
OM952_06225	COG0753	catalase activity
OM952_06230	COG0656	L-ascorbic acid biosynthetic process
OM952_06240	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
OM952_06240	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
OM952_06265	COG2814	Major facilitator Superfamily
OM952_06285	COG3328	transposase activity
OM952_06305	COG2194	sulfuric ester hydrolase activity
OM952_06320	COG0745	RESPONSE REGULATOR receiver
OM952_06325	COG0642	Histidine kinase
OM952_06335	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
OM952_06340	COG2894	cell division
OM952_06345	COG0850	regulation of cytokinetic process
OM952_06355	COG4585	Histidine kinase
OM952_06360	COG2197	response regulator
OM952_06375	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
OM952_06400	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
OM952_06410	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
OM952_06425	COG1595	DNA-templated transcription, initiation
OM952_06435	COG1946	Acyl-CoA thioesterase
OM952_06450	COG0824	Thioesterase
OM952_06455	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
OM952_06460	COG0261	This protein binds to 23S rRNA in the presence of protein L20
OM952_06465	COG0211	Belongs to the bacterial ribosomal protein bL27 family
OM952_06470	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
OM952_06475	COG0268	Binds directly to 16S ribosomal RNA
OM952_06485	COG0196	riboflavin kinase activity
OM952_06490	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
OM952_06495	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
OM952_06500	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
OM952_06515	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
OM952_06520	COG1845	cytochrome c oxidase, subunit III
OM952_06525	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
OM952_06540	COG3152	Membrane
OM952_06550	COG2207	Transcriptional regulator
OM952_06555	COG0326	Molecular chaperone. Has ATPase activity
OM952_06565	COG1366	Belongs to the anti-sigma-factor antagonist family
OM952_06570	COG1366	Belongs to the anti-sigma-factor antagonist family
OM952_06600	COG4771	TonB-dependent receptor
OM952_06610	COG5507	3-demethylubiquinone-9 3-methyltransferase
OM952_06615	COG2205	protein histidine kinase activity
OM952_06625	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
OM952_06630	COG2205	protein histidine kinase activity
OM952_06630	COG3437	response regulator, receiver
OM952_06630	COG4999	Histidine kinase
OM952_06630	COG3850	Histidine kinase
OM952_06635	COG0784	Response regulator, receiver
OM952_06635	COG4191	Histidine kinase
OM952_06660	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
OM952_06670	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
OM952_06675	COG0228	four-way junction DNA binding
OM952_06680	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
OM952_06685	COG0336	Belongs to the RNA methyltransferase TrmD family
OM952_06690	COG0335	large ribosomal subunit rRNA binding
OM952_06695	COG0534	Mate efflux family protein
OM952_06720	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
OM952_06730	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
OM952_06735	COG2801	Transposase and inactivated derivatives
OM952_06785	COG3250	beta-galactosidase activity
OM952_06790	COG3867	Arabinogalactan endo-beta-1,4-galactanase
OM952_06810	COG1960	acyl-CoA dehydrogenase activity
OM952_06840	COG0457	Tetratricopeptide repeat
OM952_06850	COG0457	Tetratricopeptide repeat
OM952_06860	COG1024	Enoyl-CoA hydratase
OM952_06860	COG1250	3-hydroxyacyl-CoA dehydrogenase
OM952_06875	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OM952_06880	COG0481	GTPase activity
OM952_06895	COG0571	ribonuclease III activity
OM952_06900	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
OM952_06905	COG1381	Involved in DNA repair and RecF pathway recombination
OM952_06915	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
OM952_06920	COG2954	triphosphatase activity
OM952_06925	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
OM952_06930	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
OM952_06935	COG3046	protein related to deoxyribodipyrimidine photolyase
OM952_06940	COG1472	Belongs to the glycosyl hydrolase 3 family
OM952_06945	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
OM952_06950	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
OM952_06955	COG1278	Cold shock
OM952_06960	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OM952_06970	COG1201	RNA secondary structure unwinding
OM952_06975	COG1793	dna ligase
OM952_06985	COG1793	dna ligase
OM952_06985	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
OM952_07020	COG0183	Belongs to the thiolase family
OM952_07045	COG1451	nucleotide metabolic process
OM952_07050	COG5487	UPF0391 membrane protein
OM952_07060	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
OM952_07075	COG1077	Cell shape determining protein MreB Mrl
OM952_07080	COG1047	Peptidyl-prolyl cis-trans
OM952_07090	COG2824	Alkylphosphonate utilization operon protein PhnA
OM952_07100	COG1902	pentaerythritol trinitrate reductase activity
OM952_07105	COG2814	Major facilitator Superfamily
OM952_07140	COG0392	lysyltransferase activity
OM952_07140	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
OM952_07150	COG0251	oxidation-reduction process
OM952_07155	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
OM952_07170	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
OM952_07195	COG1595	DNA-templated transcription, initiation
OM952_07210	COG2878	Part of a membrane complex involved in electron transport
OM952_07220	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OM952_07220	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OM952_07240	COG0346	lactoylglutathione lyase activity
OM952_07255	COG0833	amino acid
OM952_07260	COG2040	homocysteine
OM952_07270	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
OM952_07290	COG1695	Transcriptional regulator
OM952_07310	COG1981	membrane
OM952_07325	COG0825	malonyl-CoA metabolic process
OM952_07340	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
OM952_07345	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
OM952_07350	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
OM952_07355	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
OM952_07370	COG0750	zinc metalloprotease
OM952_07375	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
OM952_07380	COG0575	Belongs to the CDS family
OM952_07385	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
OM952_07390	COG0233	cytoplasmic translational termination
OM952_07395	COG0528	UMP kinase activity
OM952_07405	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
OM952_07410	COG0052	Belongs to the universal ribosomal protein uS2 family
OM952_07460	COG1393	Belongs to the ArsC family
OM952_07465	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
OM952_07475	COG0367	asparagine synthase
OM952_07485	COG4774	siderophore transport
OM952_07540	COG2801	Transposase and inactivated derivatives
OM952_07545	COG3328	transposase activity
OM952_07580	COG1566	PFAM secretion protein HlyD family protein
OM952_07585	COG2814	Major facilitator Superfamily
OM952_07615	COG3104	oligopeptide transport
OM952_07645	COG0339	signal peptide processing
OM952_07650	COG0386	Belongs to the glutathione peroxidase family
OM952_07710	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
OM952_07715	COG0084	hydrolase, TatD family'
OM952_07730	COG1960	acyl-CoA dehydrogenase activity
OM952_07745	COG0367	asparagine synthase
OM952_07755	COG0305	Participates in initiation and elongation during chromosome replication
OM952_07760	COG0415	Belongs to the DNA photolyase family
OM952_07775	COG0583	DNA-binding transcription factor activity
OM952_07820	COG3706	GGDEF domain
OM952_07845	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
OM952_07860	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
OM952_07870	COG0497	DNA recombination
OM952_07875	COG1420	regulation of RNA biosynthetic process
OM952_07880	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
OM952_07885	COG0443	Heat shock 70 kDa protein
OM952_07890	COG0484	heat shock protein binding
OM952_07895	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
OM952_07925	COG0583	DNA-binding transcription factor activity
OM952_07930	COG1132	(ABC) transporter
OM952_07965	COG2850	peptidyl-arginine hydroxylation
OM952_07985	COG1253	flavin adenine dinucleotide binding
OM952_08015	COG1131	(ABC) transporter
OM952_08020	COG1725	Transcriptional regulator
OM952_08030	COG0386	Belongs to the glutathione peroxidase family
OM952_08045	COG2900	Belongs to the SlyX family
OM952_08075	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OM952_08085	COG0646	methionine synthase
OM952_08085	COG1410	methionine synthase
OM952_08090	COG0646	methionine synthase
OM952_08090	COG1410	methionine synthase
OM952_08095	COG2226	methyltransferase
OM952_08100	COG1960	acyl-CoA dehydrogenase activity
OM952_08120	COG0557	exoribonuclease II activity
OM952_08130	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OM952_08140	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
OM952_08150	COG0704	Plays a role in the regulation of phosphate uptake
OM952_08155	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
OM952_08160	COG0581	inorganic phosphate transmembrane transporter activity
OM952_08165	COG0573	inorganic phosphate transmembrane transporter activity
OM952_08170	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
OM952_08195	COG0659	secondary active sulfate transmembrane transporter activity
OM952_08200	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
OM952_08210	COG1024	Enoyl-CoA hydratase
OM952_08220	COG0494	nUDIX hydrolase
OM952_08255	COG0488	(ABC) transporter
OM952_08265	COG0116	Belongs to the methyltransferase superfamily
OM952_08265	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
OM952_08270	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
OM952_08290	COG2925	Exonuclease
OM952_08300	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OM952_08305	COG3844	kynureninase activity
OM952_08315	COG0662	Cupin 2, conserved barrel domain protein
OM952_08320	COG0288	reversible hydration of carbon dioxide
OM952_08400	COG0017	Asparaginyl-tRNA synthetase
OM952_08405	COG0316	Belongs to the HesB IscA family
OM952_08410	COG0360	Binds together with S18 to 16S ribosomal RNA
OM952_08415	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
OM952_08420	COG0359	binds to the 23S rRNA
OM952_08430	COG3115	cell septum assembly
OM952_08440	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
OM952_08445	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
OM952_08450	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
OM952_08460	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
OM952_08470	COG4993	Dehydrogenase
OM952_08480	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
OM952_08490	COG2986	histidine ammonia-lyase
OM952_08495	COG1228	amidohydrolase
OM952_08535	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
OM952_08540	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
OM952_08545	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
OM952_08550	COG0077	Prephenate dehydratase
OM952_08550	COG1605	Chorismate mutase
OM952_08555	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
OM952_08570	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
OM952_08575	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
OM952_08580	COG0583	DNA-binding transcription factor activity
OM952_08605	COG0840	transmembrane signaling receptor activity
OM952_08625	COG4191	Histidine kinase
OM952_08625	COG0784	Response regulator, receiver
OM952_08630	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
OM952_08650	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OM952_08660	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
OM952_08670	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
OM952_08685	COG1595	DNA-templated transcription, initiation
OM952_08735	COG2244	polysaccharide biosynthetic process
OM952_08765	COG2264	protein methyltransferase activity
OM952_08790	COG1136	(ABC) transporter
OM952_08800	COG0477	Major facilitator Superfamily
OM952_08805	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OM952_08820	COG1253	flavin adenine dinucleotide binding
OM952_08830	COG0306	phosphate transporter
OM952_08855	COG0504	CTP synthase activity
OM952_08860	COG2877	3-deoxy-8-phosphooctulonate synthase activity
OM952_08870	COG0148	phosphopyruvate hydratase activity
OM952_08875	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
OM952_08885	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
OM952_08890	COG0585	pseudouridine synthase activity
OM952_08895	COG2840	Smr protein MutS2
OM952_08900	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
OM952_08905	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
OM952_08910	COG1238	metal cluster binding
OM952_08920	COG3737	Protein of unknown function (DUF498/DUF598)
OM952_08925	COG1534	Rna-binding protein
OM952_08930	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
OM952_08940	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
OM952_08945	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
OM952_08955	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
OM952_08960	COG1546	Belongs to the CinA family
OM952_08970	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
OM952_08975	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
OM952_08980	COG2137	regulation of response to DNA damage stimulus
OM952_08985	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
OM952_08990	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
OM952_09010	COG0583	DNA-binding transcription factor activity
OM952_09035	COG0351	phosphomethylpyrimidine kinase
OM952_09050	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
OM952_09055	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
OM952_09070	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OM952_09080	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
OM952_09085	COG3734	2-keto-3-deoxy-galactonokinase
OM952_09095	COG4948	Mandelate Racemase Muconate Lactonizing
OM952_09100	COG0800	Aldolase
OM952_09135	COG1501	Belongs to the glycosyl hydrolase 31 family
OM952_09145	COG1070	Carbohydrate kinase
OM952_09150	COG2115	Belongs to the xylose isomerase family
OM952_09155	COG0477	Major facilitator Superfamily
OM952_09170	COG0860	N-Acetylmuramoyl-L-alanine amidase
OM952_09175	COG1469	GTP cyclohydrolase I activity
OM952_09200	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
OM952_09205	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
OM952_09210	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
OM952_09215	COG0166	Belongs to the GPI family
OM952_09235	COG1472	Belongs to the glycosyl hydrolase 3 family
OM952_09245	COG2203	Gaf domain
OM952_09245	COG3706	GGDEF domain
OM952_09245	COG5001	Diguanylate cyclase
OM952_09245	COG4251	negative regulation of phosphorylation
OM952_09250	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
OM952_09255	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
OM952_09265	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
OM952_09270	COG0671	phosphoesterase, PA-phosphatase related
OM952_09280	COG1794	racemase activity, acting on amino acids and derivatives
OM952_09285	COG0697	spore germination
OM952_09290	COG0812	UDP-N-acetylmuramate dehydrogenase activity
OM952_09295	COG0167	dihydroorotate dehydrogenase activity
OM952_09310	COG1012	belongs to the aldehyde dehydrogenase family
OM952_09325	COG3328	transposase activity
OM952_09330	COG0366	Alpha amylase catalytic
OM952_09350	COG1082	Xylose isomerase domain protein TIM barrel
OM952_09360	COG2211	Major facilitator Superfamily
OM952_09375	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
OM952_09380	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
OM952_09395	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
OM952_09400	COG0072	phenylalanine-tRNA ligase activity
OM952_09400	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OM952_09450	COG0438	transferase activity, transferring glycosyl groups
OM952_09455	COG0438	transferase activity, transferring glycosyl groups
OM952_09465	COG0438	transferase activity, transferring glycosyl groups
OM952_09490	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OM952_09520	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
OM952_09530	COG1960	acyl-CoA dehydrogenase activity
OM952_09540	COG3040	lipid binding
OM952_09555	COG0322	excinuclease ABC activity
OM952_09570	COG0784	Response regulator, receiver
OM952_09570	COG4191	Histidine kinase
OM952_09590	COG1194	a g-specific adenine glycosylase
OM952_09595	COG0552	protein localization to endoplasmic reticulum
OM952_09605	COG3938	Belongs to the proline racemase family
OM952_09610	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OM952_09625	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OM952_09635	COG0006	proline dipeptidase activity
OM952_09650	COG0531	amino acid
OM952_09745	COG3328	transposase activity
OM952_09755	COG0840	transmembrane signaling receptor activity
OM952_09795	COG3328	transposase activity
OM952_09805	COG3039	Transposase
OM952_09825	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
OM952_09830	COG3328	transposase activity
OM952_09835	COG0460	homoserine dehydrogenase
OM952_09835	COG0527	aspartate kinase activity
OM952_09870	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OM952_09875	COG0124	histidyl-tRNA synthetase
OM952_09885	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
OM952_09890	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
OM952_09895	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
OM952_09900	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
OM952_09900	COG0131	Imidazoleglycerol-phosphate dehydratase
OM952_09905	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
OM952_09910	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
OM952_09915	COG0107	imidazoleglycerol-phosphate synthase activity
OM952_09920	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
OM952_09920	COG0140	phosphoribosyl-ATP diphosphatase activity
OM952_09935	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
OM952_09940	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
OM952_09945	COG0235	Class ii aldolase
OM952_09950	COG0531	amino acid
OM952_09955	COG0531	amino acid
OM952_09965	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
OM952_09970	COG0277	FAD linked oxidase domain protein
OM952_09990	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
OM952_10035	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OM952_10040	COG2258	MOSC domain
OM952_10045	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
OM952_10050	COG0505	Belongs to the CarA family
OM952_10060	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
OM952_10065	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
OM952_10075	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
OM952_10095	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
OM952_10105	COG0784	Response regulator, receiver
OM952_10105	COG2205	protein histidine kinase activity
OM952_10105	COG2198	Histidine kinase
OM952_10110	COG2205	protein histidine kinase activity
OM952_10110	COG2198	Histidine kinase
OM952_10110	COG0784	Response regulator, receiver
OM952_10115	COG1024	Enoyl-CoA hydratase
OM952_10120	COG0318	PFAM AMP-dependent synthetase and ligase
OM952_10155	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OM952_10165	COG2201	protein-glutamate methylesterase activity
OM952_10170	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
OM952_10180	COG0840	transmembrane signaling receptor activity
OM952_10190	COG0835	chemotaxis
OM952_10200	COG0840	transmembrane signaling receptor activity
OM952_10205	COG0840	transmembrane signaling receptor activity
OM952_10210	COG0840	transmembrane signaling receptor activity
OM952_10215	COG0840	transmembrane signaling receptor activity
OM952_10220	COG0840	transmembrane signaling receptor activity
OM952_10235	COG0840	transmembrane signaling receptor activity
OM952_10240	COG0840	transmembrane signaling receptor activity
OM952_10245	COG0840	transmembrane signaling receptor activity
OM952_10250	COG0840	transmembrane signaling receptor activity
OM952_10260	COG0840	transmembrane signaling receptor activity
OM952_10275	COG0840	transmembrane signaling receptor activity
OM952_10280	COG0840	transmembrane signaling receptor activity
OM952_10290	COG0745	RESPONSE REGULATOR receiver
OM952_10300	COG0835	chemotaxis
OM952_10305	COG1192	Involved in chromosome partitioning
OM952_10310	COG1360	Flagellar Motor Protein
OM952_10315	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
OM952_10345	COG4787	bacterial-type flagellum-dependent cell motility
OM952_10355	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
OM952_10360	COG1558	bacterial-type flagellum-dependent cell motility
OM952_10370	COG0784	Response regulator, receiver
OM952_10370	COG0835	chemotaxis
OM952_10390	COG5002	protein histidine kinase activity
OM952_10400	COG4585	Histidine kinase
OM952_10420	COG2915	High frequency lysogenization protein hflD homolog
OM952_10425	COG0482	sulfurtransferase activity
OM952_10445	COG0542	response to heat
OM952_10455	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
OM952_10465	COG0492	ferredoxin-NADP+ reductase activity
OM952_10470	COG1674	ftsk spoiiie
OM952_10480	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
OM952_10490	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
OM952_10495	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
OM952_10500	COG0183	Belongs to the thiolase family
OM952_10505	COG1024	Enoyl-CoA hydratase
OM952_10505	COG1250	3-hydroxyacyl-CoA dehydrogenase
OM952_10520	COG0820	rRNA (adenine-C2-)-methyltransferase activity
OM952_10540	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
OM952_10545	COG1160	GTP binding
OM952_10550	COG0303	'Molybdopterin
OM952_10555	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
OM952_10590	COG0708	Exodeoxyribonuclease III
OM952_10600	COG0303	'Molybdopterin
OM952_10605	COG0746	molybdenum cofactor guanylyltransferase activity
OM952_10630	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
OM952_10630	COG1648	precorrin-2 dehydrogenase activity
OM952_10640	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OM952_10645	COG2223	nitrite transmembrane transporter activity
OM952_10650	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OM952_10660	COG0243	molybdopterin cofactor binding
OM952_10680	COG3685	Protein conserved in bacteria
OM952_10700	COG5001	Diguanylate cyclase
OM952_10710	COG4566	intracellular signal transduction
OM952_10760	COG3328	transposase activity
OM952_10900	COG3039	Transposase
OM952_10950	COG3328	transposase activity
OM952_10965	COG1073	alpha beta
OM952_10965	COG2226	methyltransferase
OM952_10980	COG0363	glucosamine-6-phosphate deaminase activity
OM952_11060	COG3328	transposase activity
OM952_11080	COG1192	Involved in chromosome partitioning
OM952_11125	COG3318	Belongs to the UPF0149 family
OM952_11125	COG3012	SEC-C Motif Domain Protein
OM952_11155	COG3328	transposase activity
OM952_11185	COG1309	transcriptional regulator
OM952_11200	COG2154	pterin-4-alpha-carbinolamine dehydratase
OM952_11210	COG0428	transporter
OM952_11215	COG3064	Membrane
OM952_11225	COG1530	ribonuclease E activity
OM952_11230	COG3039	Transposase
OM952_11240	COG1054	Belongs to the UPF0176 family
OM952_11260	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
OM952_11285	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
OM952_11290	COG0322	excinuclease ABC activity
OM952_11300	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
OM952_11305	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
OM952_11310	COG1663	tetraacyldisaccharide 4'-kinase activity
OM952_11315	COG1132	(ABC) transporter
OM952_11325	COG0811	peptide transport
OM952_11340	COG1136	(ABC) transporter
OM952_11345	COG4591	ABC-type transport system involved in lipoprotein release permease component
OM952_11355	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
OM952_11360	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
OM952_11375	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
OM952_11390	COG0354	folic acid binding
OM952_11400	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
OM952_11405	COG0837	glucose binding
OM952_11410	COG0363	glucosamine-6-phosphate deaminase activity
OM952_11415	COG0129	dihydroxy-acid dehydratase activity
OM952_11420	COG0800	Aldolase
OM952_11485	COG0784	Response regulator, receiver
OM952_11485	COG2205	protein histidine kinase activity
OM952_11490	COG2183	response to ionizing radiation
OM952_11500	COG0723	plastoquinol--plastocyanin reductase activity
OM952_11500	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OM952_11515	COG3243	poly(R)-hydroxyalkanoic acid synthase
OM952_11525	COG1183	phosphatidylcholine synthase activity
OM952_11530	COG1028	Short-chain dehydrogenase reductase Sdr
OM952_11545	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
OM952_11560	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
OM952_11575	COG1914	H( )-stimulated, divalent metal cation uptake system
OM952_11595	COG2814	Major facilitator Superfamily
OM952_11610	COG1335	isochorismatase
OM952_11625	COG2197	response regulator
OM952_11655	COG0583	DNA-binding transcription factor activity
OM952_11660	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
OM952_11665	COG3002	Belongs to the UPF0753 family
OM952_11675	COG0604	alcohol dehydrogenase
OM952_11680	COG3384	dioxygenase
OM952_11690	COG2801	Transposase and inactivated derivatives
OM952_11700	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
OM952_11715	COG0583	DNA-binding transcription factor activity
OM952_11760	COG0518	GMP synthase (glutamine-hydrolyzing) activity
OM952_11760	COG0519	Catalyzes the synthesis of GMP from XMP
OM952_11770	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
OM952_11780	COG0475	glutathione-regulated potassium exporter activity
OM952_11780	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
OM952_11785	COG1210	Utp--glucose-1-phosphate uridylyltransferase
OM952_11795	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
OM952_11800	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
OM952_11810	COG0776	regulation of translation
OM952_11815	COG0539	negative regulation of cytoplasmic translation
OM952_11820	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
OM952_11835	COG2957	Belongs to the agmatine deiminase family
OM952_11840	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OM952_11865	COG0395	ABC-type sugar transport system, permease component
OM952_11870	COG1175	transmembrane transport
OM952_11900	COG2350	Protein conserved in bacteria
OM952_11905	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
OM952_11910	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
OM952_11915	COG1187	pseudouridine synthase activity
OM952_11930	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OM952_11935	COG0436	Aminotransferase
OM952_11940	COG4133	protoheme IX ABC transporter activity
OM952_11960	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
OM952_11985	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OM952_11995	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
OM952_12000	COG4988	ABC transporter
OM952_12010	COG1294	oxidase, subunit
OM952_12040	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
OM952_12045	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
OM952_12055	COG0165	Argininosuccinate lyase
OM952_12060	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
OM952_12070	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
OM952_12075	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
OM952_12085	COG0137	argininosuccinate synthase activity
OM952_12090	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
OM952_12100	COG0215	cysteine-tRNA ligase activity
OM952_12105	COG2166	iron-sulfur cluster assembly
OM952_12125	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
OM952_12130	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
OM952_12155	COG4302	ethanolamine ammonia-lyase activity
OM952_12185	COG3039	Transposase
OM952_12215	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
OM952_12220	COG0402	S-adenosylhomocysteine deaminase activity
OM952_12230	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
OM952_12235	COG1509	lysine 2,3-aminomutase activity
OM952_12240	COG5001	Diguanylate cyclase
OM952_12240	COG3300	MHYT domain
OM952_12255	COG0483	inositol monophosphate 1-phosphatase activity
OM952_12260	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
OM952_12275	COG0488	(ABC) transporter
OM952_12280	COG0513	Belongs to the DEAD box helicase family
OM952_12285	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
OM952_12290	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
OM952_12305	COG0625	glutathione transferase activity
OM952_12315	COG4681	YaeQ
OM952_12320	COG2081	HI0933 family
OM952_12330	COG0501	Belongs to the peptidase M48B family
OM952_12335	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OM952_12340	COG1028	Short-chain dehydrogenase reductase Sdr
OM952_12365	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
OM952_12370	COG0860	N-Acetylmuramoyl-L-alanine amidase
OM952_12375	COG0802	atpase or kinase
OM952_12380	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
OM952_12380	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
OM952_12385	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
OM952_12390	COG1570	exodeoxyribonuclease VII activity
OM952_12400	COG1262	PFAM Formylglycine-generating sulfatase enzyme
OM952_12445	COG0835	chemotaxis
OM952_12450	COG0840	transmembrane signaling receptor activity
OM952_12455	COG2094	Belongs to the DNA glycosylase MPG family
OM952_12460	COG1201	RNA secondary structure unwinding
OM952_12480	COG2969	positive regulation of protein catabolic process
OM952_12485	COG0625	glutathione transferase activity
OM952_12490	COG2857	Cytochrome c1
OM952_12495	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
OM952_12500	COG0723	plastoquinol--plastocyanin reductase activity
OM952_12505	COG0741	lytic transglycosylase activity
OM952_12520	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
OM952_12525	COG1702	phosphate starvation-inducible protein PhoH
OM952_12535	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
OM952_12545	COG4535	Mg2 and Co2 transporter CorC
OM952_12560	COG1012	belongs to the aldehyde dehydrogenase family
OM952_12565	COG1177	transmembrane transport
OM952_12570	COG1176	ABC-type spermidine putrescine transport system, permease component I
OM952_12575	COG3842	ATPase activity
OM952_12595	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
OM952_12615	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
OM952_12620	COG0174	glutamine synthetase
OM952_12625	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OM952_12635	COG2703	oxygen carrier activity
OM952_12640	COG0477	Major facilitator Superfamily
OM952_12650	COG0243	molybdopterin cofactor binding
OM952_12655	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
OM952_12660	COG2223	nitrite transmembrane transporter activity
OM952_12670	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
OM952_12680	COG2733	membrane
OM952_12685	COG2205	protein histidine kinase activity
OM952_12685	COG5002	protein histidine kinase activity
OM952_12685	COG0784	Response regulator, receiver
OM952_12695	COG0477	Major facilitator Superfamily
OM952_12700	COG0840	transmembrane signaling receptor activity
OM952_12730	COG2902	Dehydrogenase
OM952_12740	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OM952_12745	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OM952_12750	COG1609	Transcriptional regulator
OM952_12755	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
OM952_12755	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
OM952_12760	COG1105	Belongs to the carbohydrate kinase PfkB family
OM952_12765	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OM952_12765	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OM952_12785	COG3328	transposase activity
OM952_12790	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OM952_12800	COG1862	Preprotein translocase
OM952_12805	COG0343	queuine tRNA-ribosyltransferase activity
OM952_12810	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
OM952_12845	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
OM952_12850	COG3291	Pkd domain containing protein
OM952_12855	COG0405	Gamma-glutamyltransferase
OM952_12860	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
OM952_12870	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
OM952_12875	COG0742	ribosomal rna small subunit methyltransferase
OM952_12880	COG0326	Molecular chaperone. Has ATPase activity
OM952_12955	COG3702	type iv secretory pathway
OM952_12975	COG2948	multi-organism process
OM952_12995	COG3505	Type IV secretory pathway VirD4
OM952_13010	COG0556	nucleotide-excision repair
OM952_13190	COG3179	chitinase
OM952_13235	COG4695	Portal protein
OM952_13315	COG3328	transposase activity
OM952_13325	COG1611	Belongs to the LOG family
OM952_13335	COG2095	MarC family integral membrane protein
OM952_13345	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
OM952_13380	COG1185	polyribonucleotide nucleotidyltransferase activity
OM952_13385	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
OM952_13390	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
OM952_13395	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
OM952_13400	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
OM952_13405	COG0195	Participates in both transcription termination and antitermination
OM952_13410	COG0779	Required for maturation of 30S ribosomal subunits
OM952_13420	COG1007	ATP synthesis coupled electron transport
OM952_13445	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OM952_13450	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
OM952_13460	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
OM952_13465	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
OM952_13470	COG0649	NAD binding
OM952_13475	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OM952_13480	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OM952_13485	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OM952_13500	COG0149	triose-phosphate isomerase activity
OM952_13505	COG4221	oxidoreductase activity
OM952_13535	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OM952_13540	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
OM952_13545	COG0159	tryptophan synthase activity
OM952_13555	COG0133	tryptophan synthase activity
OM952_13565	COG0135	phosphoribosylanthranilate isomerase activity
OM952_13570	COG0101	tRNA pseudouridine synthase activity
OM952_13585	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
OM952_13590	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OM952_13595	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
OM952_13600	COG2890	protein-(glutamine-N5) methyltransferase activity
OM952_13610	COG0688	phosphatidylethanolamine metabolic process
OM952_13620	COG0433	COG0433 Predicted ATPase
OM952_13645	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
OM952_13650	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
OM952_13675	COG0717	Belongs to the dCTP deaminase family
OM952_13680	COG0489	protein tyrosine kinase activity
OM952_13710	COG3590	peptidase
OM952_13735	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OM952_13740	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OM952_13745	COG2311	Membrane
OM952_13750	COG1047	Peptidyl-prolyl cis-trans
OM952_13755	COG0791	NLP P60 protein
OM952_13760	COG0791	NLP P60 protein
OM952_13770	COG4106	trans-aconitate 2-methyltransferase activity
OM952_13775	COG1301	dicarboxylic acid transport
OM952_13780	COG1785	Belongs to the alkaline phosphatase family
OM952_13785	COG0037	tRNA processing
OM952_13790	COG1722	exodeoxyribonuclease VII activity
OM952_13795	COG0142	geranyltranstransferase activity
OM952_13800	COG4104	PAAR repeat-containing protein
OM952_13810	COG0312	modulator of DNA gyrase
OM952_13815	COG3028	Belongs to the UPF0307 family
OM952_13820	COG0312	modulator of DNA gyrase
OM952_13830	COG3164	Protein of unknown function
OM952_13840	COG0424	maF-like protein
OM952_13845	COG2968	Membrane
OM952_13860	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
OM952_13875	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
OM952_13890	COG0495	leucyl-tRNA aminoacylation
OM952_13900	COG3118	belongs to the thioredoxin family
OM952_13925	COG2155	Conserved Protein
OM952_13975	COG1132	(ABC) transporter
OM952_14005	COG0745	RESPONSE REGULATOR receiver
OM952_14010	COG5002	protein histidine kinase activity
OM952_14010	COG5000	phosphorelay sensor kinase activity
OM952_14015	COG0475	glutathione-regulated potassium exporter activity
OM952_14025	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
OM952_14045	COG1187	pseudouridine synthase activity
OM952_14050	COG5002	protein histidine kinase activity
OM952_14050	COG5001	Diguanylate cyclase
OM952_14060	COG1595	DNA-templated transcription, initiation
OM952_14175	COG0667	Aldo Keto reductase
OM952_14180	COG2814	Major facilitator Superfamily
OM952_14185	COG0583	DNA-binding transcription factor activity
OM952_14195	COG2207	Transcriptional regulator
OM952_14205	COG1309	transcriptional regulator
OM952_14215	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OM952_14230	COG0735	belongs to the Fur family
OM952_14235	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OM952_14260	COG4452	Inner membrane protein CreD
OM952_14280	COG0745	RESPONSE REGULATOR receiver
OM952_14285	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
OM952_14300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
OM952_14310	COG2198	Histidine kinase
OM952_14310	COG0643	Histidine kinase
OM952_14315	COG0840	transmembrane signaling receptor activity
OM952_14320	COG0835	chemotaxis
OM952_14325	COG2199	diguanylate cyclase activity
OM952_14325	COG2200	EAL domain
OM952_14325	COG2202	Pas domain
OM952_14330	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
OM952_14335	COG2201	protein-glutamate methylesterase activity
OM952_14345	COG3590	peptidase
OM952_14360	COG1515	deoxyribonuclease V activity
OM952_14370	COG1741	Belongs to the pirin family
OM952_14385	COG1741	Belongs to the pirin family
OM952_14390	COG1966	Carbon starvation protein
OM952_14395	COG2879	small protein
OM952_14430	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
OM952_14435	COG1529	Aldehyde oxidase and xanthine dehydrogenase
OM952_14440	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
OM952_14445	COG2080	2 iron, 2 sulfur cluster binding
OM952_14450	COG0604	alcohol dehydrogenase
OM952_14450	COG1028	Short-chain dehydrogenase reductase Sdr
OM952_14450	COG3321	synthase
OM952_14455	COG2203	Gaf domain
OM952_14455	COG4251	negative regulation of phosphorylation
OM952_14455	COG3706	GGDEF domain
OM952_14455	COG5001	Diguanylate cyclase
OM952_14460	COG0629	single-stranded DNA binding
OM952_14465	COG0142	geranyltranstransferase activity
OM952_14475	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
OM952_14490	COG0527	aspartate kinase activity
OM952_14495	COG0384	phenazine biosynthesis protein PhzF
OM952_14500	COG0384	phenazine biosynthesis protein PhzF
OM952_14510	COG1764	response to oxidative stress
OM952_14515	COG0540	Belongs to the ATCase OTCase family
OM952_14520	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
OM952_14525	COG1678	Uncharacterized ACR, COG1678
OM952_14530	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
OM952_14535	COG0519	Catalyzes the synthesis of GMP from XMP
OM952_14560	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
OM952_14575	COG0739	heme binding
OM952_14595	COG0693	protein deglycase activity
OM952_14605	COG1959	2 iron, 2 sulfur cluster binding
OM952_14610	COG0719	Fe-S assembly protein
OM952_14615	COG0396	ATPase activity
OM952_14620	COG0719	Fe-S assembly protein
OM952_14625	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
OM952_14630	COG0456	acetyltransferase
OM952_14635	COG2146	nitrite reductase [NAD(P)H] activity
OM952_14640	COG4774	siderophore transport
OM952_14645	COG3128	pkhd-type hydroxylase
OM952_14670	COG3328	transposase activity
OM952_14675	COG1477	protein flavinylation
OM952_14680	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
OM952_14690	COG1555	photosystem II stabilization
OM952_14710	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
OM952_14720	COG0628	permease
OM952_14730	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
OM952_14745	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
OM952_14765	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
OM952_14770	COG0271	Belongs to the BolA IbaG family
OM952_14780	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
OM952_14790	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
OM952_14795	COG1137	ATPase activity
OM952_14810	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
OM952_14815	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
OM952_14820	COG1660	Displays ATPase and GTPase activities
OM952_14830	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
OM952_14845	COG2239	Acts as a magnesium transporter
OM952_14855	COG1294	oxidase, subunit
OM952_14905	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OM952_14905	COG0551	DNA topoisomerase type I activity
OM952_14920	COG2951	lytic endotransglycosylase activity
OM952_14990	COG1271	oxidase subunit
OM952_15000	COG1113	amino acid transport
OM952_15025	COG2197	response regulator
OM952_15030	COG0531	amino acid
OM952_15095	COG2814	Major facilitator Superfamily
OM952_15100	COG0754	glutathionylspermidine amidase activity
OM952_15125	COG1842	Phage shock protein A
OM952_15135	COG0259	pyridoxamine-phosphate oxidase activity
OM952_15140	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
OM952_15145	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
OM952_15155	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
OM952_15160	COG2814	Major facilitator Superfamily
OM952_15185	COG2198	Histidine kinase
OM952_15185	COG2205	protein histidine kinase activity
OM952_15185	COG0784	Response regulator, receiver
OM952_15190	COG2353	YceI-like domain
OM952_15210	COG1760	l-serine dehydratase
OM952_15220	COG0527	aspartate kinase activity
OM952_15220	COG0460	homoserine dehydrogenase
OM952_15225	COG0626	cystathionine gamma-synthase activity
OM952_15230	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OM952_15235	COG0739	heme binding
OM952_15240	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
OM952_15245	COG1272	protein, Hemolysin III
OM952_15250	COG2982	Protein involved in outer membrane biogenesis
OM952_15255	COG0516	GMP reductase activity
OM952_15255	COG0517	IMP dehydrogenase activity
OM952_15260	COG0463	Glycosyl transferase, family 2
OM952_15265	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OM952_15270	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
OM952_15280	COG4771	TonB-dependent receptor
OM952_15285	COG1309	transcriptional regulator
OM952_15295	COG1960	acyl-CoA dehydrogenase activity
OM952_15320	COG3328	transposase activity
OM952_15345	COG0509	glycine decarboxylation via glycine cleavage system
OM952_15350	COG0404	The glycine cleavage system catalyzes the degradation of glycine
OM952_15360	COG0330	HflC and HflK could
OM952_15365	COG1742	UPF0060 membrane protein
OM952_15370	COG3956	TIGRFAM MazG family protein
OM952_15380	COG0494	nUDIX hydrolase
OM952_15390	COG1385	rRNA (uridine-N3-)-methyltransferase activity
OM952_15395	COG0837	glucose binding
OM952_15420	COG3858	chitin binding
OM952_15420	COG1388	LysM domain
OM952_15425	COG3525	Glycosyl hydrolase, family 20, catalytic domain
OM952_15435	COG1472	Belongs to the glycosyl hydrolase 3 family
OM952_15490	COG3142	Participates in the control of copper homeostasis
OM952_15495	COG1446	asparaginase
OM952_15520	COG0643	Histidine kinase
OM952_15520	COG0784	Response regulator, receiver
OM952_15520	COG2198	Histidine kinase
OM952_15525	COG0840	transmembrane signaling receptor activity
OM952_15530	COG0835	chemotaxis
OM952_15545	COG0189	ligase activity
OM952_15555	COG1397	ADP-ribosylglycohydrolase
OM952_15565	COG1199	ATP-dependent helicase activity
OM952_15575	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OM952_15580	COG1215	transferase activity, transferring glycosyl groups
OM952_15590	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
OM952_15600	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
OM952_15605	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
OM952_15610	COG0535	radical SAM domain protein
OM952_15615	COG0535	radical SAM domain protein
OM952_15630	COG0837	glucose binding
OM952_15640	COG3328	transposase activity
OM952_15650	COG1643	Atp-dependent helicase
OM952_15655	COG0783	Belongs to the Dps family
OM952_15660	COG0514	ATP-dependent DNA helicase (RecQ)
OM952_15695	COG0840	transmembrane signaling receptor activity
OM952_15715	COG3920	Histidine kinase
OM952_15720	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
OM952_15730	COG0602	queuosine metabolic process
OM952_15740	COG2885	chlorophyll binding
OM952_15745	COG0823	Involved in the tonB-independent uptake of proteins
OM952_15755	COG0848	biopolymer transport protein
OM952_15765	COG0824	Thioesterase
OM952_15770	COG2255	four-way junction helicase activity
OM952_15780	COG3158	transport of potassium into the cell
OM952_15785	COG0632	four-way junction helicase activity
OM952_15790	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
OM952_15795	COG0217	transcriptional regulatory protein
OM952_15810	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
OM952_15825	COG0477	Major facilitator Superfamily
OM952_15845	COG0657	acetylesterase activity
OM952_15845	COG2755	lipolytic protein G-D-S-L family
OM952_15865	COG0488	(ABC) transporter
OM952_15930	COG4772	TonB-dependent receptor
OM952_15940	COG4264	IucA IucC family
OM952_15955	COG0019	diaminopimelate decarboxylase activity
OM952_15985	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
OM952_15995	COG1492	cobalamin metabolic process
OM952_16005	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
OM952_16030	COG4206	TonB-dependent receptor
OM952_16040	COG0542	response to heat
OM952_16085	COG1877	trehalose-phosphatase activity
OM952_16090	COG3387	PFAM Glycoside hydrolase 15-related
OM952_16110	COG0840	transmembrane signaling receptor activity
OM952_16115	COG3011	Protein conserved in bacteria
OM952_16130	COG0564	pseudouridine synthase activity
OM952_16135	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
OM952_16145	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OM952_16145	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
OM952_16160	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
OM952_16165	COG0045	succinate-CoA ligase (ADP-forming) activity
OM952_16210	COG3328	transposase activity
OM952_16220	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
OM952_16225	COG0237	dephospho-CoA kinase activity
OM952_16250	COG0745	RESPONSE REGULATOR receiver
OM952_16260	COG0189	ligase activity
OM952_16290	COG2801	Transposase and inactivated derivatives
OM952_16305	COG2003	Belongs to the UPF0758 family
OM952_16330	COG3328	transposase activity
OM952_16410	COG2003	Belongs to the UPF0758 family
OM952_16480	COG2022	thiamine diphosphate biosynthetic process
OM952_16485	COG0220	tRNA (guanine-N7-)-methyltransferase activity
OM952_16490	COG0471	metal ion transport
OM952_16490	COG3273	potassium ion transport
OM952_16515	COG1970	mechanosensitive ion channel activity
OM952_16525	COG1609	Transcriptional regulator
OM952_16535	COG3250	beta-galactosidase activity
OM952_16540	COG4948	Mandelate Racemase Muconate Lactonizing
OM952_16550	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OM952_16560	COG0308	aminopeptidase N
OM952_16565	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OM952_16575	COG2895	sulfate adenylyltransferase (ATP) activity
OM952_16575	COG0529	Catalyzes the synthesis of activated sulfate
OM952_16585	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
OM952_16590	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OM952_16595	COG0175	sulfate reduction
OM952_16615	COG2205	protein histidine kinase activity
OM952_16615	COG2198	Histidine kinase
OM952_16615	COG0784	Response regulator, receiver
OM952_16630	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
OM952_16630	COG1648	precorrin-2 dehydrogenase activity
OM952_16645	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
OM952_16650	COG3588	fructose-bisphosphate aldolase
OM952_16655	COG0469	pyruvate kinase activity
OM952_16665	COG0126	phosphoglycerate kinase activity
OM952_16695	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
OM952_16705	COG3047	cAMP biosynthetic process
OM952_16720	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OM952_16720	COG3453	Protein conserved in bacteria
OM952_16725	COG0725	ABC transporter, periplasmic molybdate-binding protein
OM952_16730	COG4149	molybdate abc transporter
OM952_16735	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
OM952_16755	COG0642	Histidine kinase
OM952_16780	COG1022	Amp-dependent synthetase and ligase
OM952_16805	COG1376	ErfK ybiS ycfS ynhG family protein
OM952_16810	COG0739	heme binding
OM952_16815	COG4773	Receptor
OM952_16830	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
OM952_16835	COG1301	dicarboxylic acid transport
OM952_16845	COG2304	oxidoreductase activity
OM952_16865	COG0714	Associated with various cellular activities
OM952_16895	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
OM952_16915	COG1957	nucleoside hydrolase
OM952_16920	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
OM952_16930	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
OM952_16945	COG1561	YicC-like family, N-terminal region
OM952_16950	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
OM952_16960	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
OM952_16965	COG0635	Involved in the biosynthesis of porphyrin-containing compound
OM952_16980	COG0006	proline dipeptidase activity
OM952_16990	COG0006	proline dipeptidase activity
OM952_16995	COG3079	Belongs to the UPF0149 family
OM952_17015	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
OM952_17035	COG2912	Transglutaminase-like superfamily
OM952_17040	COG1773	rubredoxin
OM952_17045	COG0352	thiamine-phosphate diphosphorylase activity
OM952_17065	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
OM952_17075	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
OM952_17080	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
OM952_17110	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
OM952_17115	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OM952_17120	COG1028	Short-chain dehydrogenase reductase Sdr
OM952_17130	COG0671	phosphoesterase, PA-phosphatase related
OM952_17140	COG3781	membrane
OM952_17150	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
OM952_17155	COG0563	adenylate kinase activity
OM952_17170	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
OM952_17180	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
OM952_17200	COG3710	Transcriptional regulator
OM952_17205	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
OM952_17215	COG0840	transmembrane signaling receptor activity
OM952_17220	COG0405	Gamma-glutamyltransferase
OM952_17225	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
OM952_17245	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
OM952_17250	COG0473	3-isopropylmalate dehydrogenase activity
OM952_17255	COG0066	3-isopropylmalate dehydratase activity
OM952_17260	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
OM952_17280	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
OM952_17285	COG1538	Outer membrane efflux protein
OM952_17290	COG1519	Transferase
OM952_17295	COG1560	Kdo2-lipid A biosynthetic process
OM952_17320	COG0281	malic enzyme
OM952_17320	COG0280	phosphate acetyltransferase
OM952_17325	COG1301	dicarboxylic acid transport
OM952_17350	COG0583	DNA-binding transcription factor activity
OM952_17355	COG0667	Aldo Keto reductase
OM952_17370	COG2197	response regulator
OM952_17380	COG0642	Histidine kinase
OM952_17395	COG2851	Citrate transporter
OM952_17400	COG1028	Short-chain dehydrogenase reductase Sdr
OM952_17405	COG1609	Transcriptional regulator
OM952_17410	COG2211	Major facilitator Superfamily
OM952_17435	COG1162	GTPase activity
OM952_17440	COG0436	Aminotransferase
OM952_17455	COG0726	polysaccharide deacetylase
OM952_17460	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
OM952_17475	COG3964	amidohydrolase
OM952_17480	COG0402	S-adenosylhomocysteine deaminase activity
OM952_17505	COG3328	transposase activity
OM952_17515	COG1307	EDD domain protein, DegV family
OM952_17530	COG2801	Transposase and inactivated derivatives
OM952_17540	COG3791	Glutathione-dependent formaldehyde-activating
OM952_17570	COG2205	protein histidine kinase activity
OM952_17585	COG0218	Necessary for normal cell division and for the maintenance of normal septation
OM952_17600	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
OM952_17610	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
OM952_17615	COG1012	belongs to the aldehyde dehydrogenase family
OM952_17620	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
OM952_17645	COG1183	phosphatidylcholine synthase activity
OM952_17655	COG0442	prolyl-tRNA aminoacylation
OM952_17670	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
OM952_17675	COG1127	ABC transporter
OM952_17680	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
OM952_17680	COG3218	ABC-type transport auxiliary lipoprotein component
OM952_17710	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OM952_17715	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
OM952_17715	COG0662	Cupin 2, conserved barrel domain protein
OM952_17745	COG2086	electron transfer activity
OM952_17760	COG0546	phosphoglycolate phosphatase activity
OM952_17760	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
OM952_17765	COG0277	FAD linked oxidase domain protein
OM952_17775	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OM952_17810	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
OM952_17815	COG0438	transferase activity, transferring glycosyl groups
OM952_17835	COG0438	transferase activity, transferring glycosyl groups
OM952_17840	COG0626	cystathionine gamma-synthase activity
OM952_17870	COG0625	glutathione transferase activity
OM952_17880	COG0513	Belongs to the DEAD box helicase family
OM952_17885	COG0720	synthase
OM952_17895	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
OM952_17905	COG1956	GAF domain-containing protein
OM952_17920	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OM952_17925	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
OM952_17935	COG4991	sh3 domain protein
OM952_17945	COG0339	signal peptide processing
OM952_17960	COG2132	Multicopper oxidase
OM952_17995	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
OM952_18000	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OM952_18005	COG1136	(ABC) transporter
OM952_18010	COG0577	efflux transmembrane transporter activity
OM952_18010	COG1136	(ABC) transporter
OM952_18030	COG4191	Histidine kinase
OM952_18035	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
OM952_18060	COG0355	proton-transporting ATP synthase activity, rotational mechanism
OM952_18065	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
OM952_18070	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
OM952_18075	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
OM952_18080	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
OM952_18095	COG0356	it plays a direct role in the translocation of protons across the membrane
OM952_18115	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OM952_18125	COG0508	dehydrogenase complex catalyzes the overall conversion of
OM952_18160	COG2011	ABC-type metal ion transport system permease component
OM952_18165	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
OM952_18170	COG0697	spore germination
OM952_18175	COG1666	GTP binding
OM952_18185	COG2198	Histidine kinase
OM952_18185	COG0784	Response regulator, receiver
OM952_18185	COG5002	protein histidine kinase activity
OM952_18210	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OM952_18215	COG1187	pseudouridine synthase activity
OM952_18220	COG2813	Specifically methylates the guanine in position
OM952_18235	COG3039	Transposase
OM952_18240	COG3328	transposase activity
OM952_18255	COG2205	protein histidine kinase activity
OM952_18255	COG2202	Pas domain
OM952_18275	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
OM952_18280	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OM952_18335	COG0842	Transport permease protein
OM952_18340	COG1131	(ABC) transporter
OM952_18345	COG0025	NhaP-type Na H and K H
OM952_18350	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
OM952_18355	COG1573	uracil-dna glycosylase
OM952_18365	COG3384	dioxygenase
OM952_18375	COG0583	DNA-binding transcription factor activity
OM952_18385	COG0667	Aldo Keto reductase
OM952_18400	COG3590	peptidase
OM952_18415	COG0531	amino acid
OM952_18430	COG2972	Histidine kinase
OM952_18445	COG3685	Protein conserved in bacteria
OM952_18450	COG3546	catalase activity
OM952_18500	COG1271	oxidase subunit
OM952_18505	COG1294	oxidase, subunit
OM952_18520	COG1028	Short-chain dehydrogenase reductase Sdr
OM952_18540	COG1063	alcohol dehydrogenase
OM952_18550	COG3328	transposase activity
OM952_18620	COG0251	oxidation-reduction process
OM952_18650	COG0659	secondary active sulfate transmembrane transporter activity
OM952_18655	COG0038	chloride channel
OM952_18665	COG0024	Methionine aminopeptidase
OM952_18680	COG1028	Short-chain dehydrogenase reductase Sdr
OM952_18700	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OM952_18705	COG1490	D-aminoacyl-tRNA deacylase activity
OM952_18710	COG1560	Kdo2-lipid A biosynthetic process
OM952_18755	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
OM952_18755	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
OM952_18760	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
OM952_18765	COG0242	peptide deformylase activity
OM952_18770	COG1652	LysM domain
OM952_18775	COG0758	DNA mediated transformation
OM952_18795	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OM952_18795	COG1754	DNA topoisomerase type I activity
OM952_18800	COG0009	L-threonylcarbamoyladenylate synthase
OM952_18815	COG1028	Short-chain dehydrogenase reductase Sdr
OM952_18825	COG0616	signal peptide processing
OM952_18830	COG0534	Mate efflux family protein
OM952_18850	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
OM952_18855	COG0625	glutathione transferase activity
OM952_18875	COG2860	membrane
OM952_18880	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OM952_18885	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
OM952_18890	COG2201	protein-glutamate methylesterase activity
OM952_18895	COG2177	Part of the ABC transporter FtsEX involved in
OM952_18900	COG2884	Cell division ATP-binding protein ftsE
OM952_18905	COG0513	Belongs to the DEAD box helicase family
OM952_18910	COG3118	belongs to the thioredoxin family
OM952_18915	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
OM952_18925	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
OM952_18950	COG1652	LysM domain
OM952_18955	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
OM952_18955	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
OM952_18960	COG1473	amidohydrolase
OM952_18965	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OM952_18970	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OM952_18990	COG5383	Protein conserved in bacteria
OM952_19030	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
OM952_19035	COG3023	N-Acetylmuramoyl-L-alanine amidase
OM952_19055	COG0531	amino acid
OM952_19075	COG3328	transposase activity
OM952_19085	COG2133	pyrroloquinoline quinone binding
OM952_19095	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
OM952_19100	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
OM952_19115	COG1610	YqeY-like protein
OM952_19120	COG1295	ribonuclease BN
OM952_19125	COG0358	DNA primase activity
OM952_19140	COG0109	protoheme IX farnesyltransferase activity
OM952_19170	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
OM952_19185	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
OM952_19225	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
OM952_19230	COG0739	heme binding
OM952_19235	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
OM952_19245	COG2223	nitrite transmembrane transporter activity
OM952_19250	COG0708	Exodeoxyribonuclease III
OM952_19255	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
OM952_19265	COG1192	Involved in chromosome partitioning
OM952_19270	COG1475	DNA binding
OM952_19285	COG0463	Glycosyl transferase, family 2
OM952_19305	COG0756	dUTP diphosphatase activity
OM952_19310	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
OM952_19315	COG2003	Belongs to the UPF0758 family
OM952_19320	COG0018	arginyl-trna synthetase
OM952_19335	COG4221	oxidoreductase activity
OM952_19340	COG2755	lipolytic protein G-D-S-L family
OM952_19340	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
OM952_19365	COG1166	arginine decarboxylase activity
OM952_19370	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
OM952_19390	COG3525	Glycosyl hydrolase, family 20, catalytic domain
OM952_19390	COG3291	Pkd domain containing protein
OM952_19405	COG0606	chelatase, subunit chli
OM952_19420	COG4943	cyclic-guanylate-specific phosphodiesterase activity
OM952_19445	COG1690	Belongs to the RtcB family
OM952_19485	COG1090	epimerase
OM952_19495	COG0642	Histidine kinase
OM952_19515	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OM952_19540	COG1011	Hydrolase
OM952_19545	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
OM952_19560	COG0753	catalase activity
OM952_19575	COG2197	response regulator
OM952_19580	COG4585	Histidine kinase
OM952_19585	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OM952_19590	COG1136	(ABC) transporter
OM952_19615	COG0697	spore germination
OM952_19640	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OM952_19645	COG0180	Tryptophanyl-tRNA synthetase
OM952_19650	COG3237	CsbD-like
OM952_19690	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
OM952_19705	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
OM952_19710	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
OM952_19710	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
OM952_19720	COG3228	Belongs to the MtfA family
OM952_19750	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OM952_19795	COG3328	transposase activity
OM952_19810	COG1199	ATP-dependent helicase activity
OM952_19825	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
OM952_19915	COG4555	ABC transporter
OM952_19925	COG1476	TRANSCRIPTIONal
OM952_19945	COG1230	cation diffusion facilitator family transporter
OM952_19950	COG0543	2 iron, 2 sulfur cluster binding
OM952_19950	COG0633	Ferredoxin
OM952_19955	COG1131	(ABC) transporter
OM952_19960	COG0842	Transport permease protein
OM952_19965	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
OM952_19990	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OM952_20010	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OM952_20015	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OM952_20030	COG0045	succinate-CoA ligase (ADP-forming) activity
OM952_20030	COG1042	CoA-binding domain protein
OM952_20030	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OM952_20035	COG2239	Acts as a magnesium transporter
OM952_20055	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
OM952_20060	COG3387	PFAM Glycoside hydrolase 15-related
OM952_20075	COG3100	YcgL domain-containing protein
OM952_20080	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
OM952_20090	COG0463	Glycosyl transferase, family 2
OM952_20100	COG1028	Short-chain dehydrogenase reductase Sdr
OM952_20155	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OM952_20190	COG0408	coproporphyrinogen oxidase activity
OM952_20225	COG0515	serine threonine protein kinase
OM952_20230	COG0631	protein serine/threonine phosphatase activity
OM952_20255	COG0667	Aldo Keto reductase
OM952_20260	COG0583	DNA-binding transcription factor activity
OM952_20335	COG0154	amidase activity
OM952_20360	COG3328	transposase activity
OM952_20440	COG0210	DNA helicase
OM952_20455	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OM952_20460	COG0583	DNA-binding transcription factor activity
OM952_20465	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
OM952_20475	COG2159	amidohydrolase
OM952_20500	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OM952_20520	COG0357	Ribosomal RNA small subunit methyltransferase G
OM952_20525	COG3540	Alkaline phosphatase
OM952_20535	COG2091	lysine biosynthetic process via aminoadipic acid
OM952_20550	COG0708	Exodeoxyribonuclease III
OM952_20555	COG1940	carbohydrate kinase activity
OM952_20555	COG1846	Transcriptional regulator
OM952_20575	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OM952_20580	COG3162	membrane
OM952_20590	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OM952_20625	COG3507	Belongs to the glycosyl hydrolase 43 family
OM952_20645	COG1028	Short-chain dehydrogenase reductase Sdr
OM952_20650	COG0179	Fumarylacetoacetate (FAA) hydrolase
OM952_20655	COG4948	Mandelate Racemase Muconate Lactonizing
OM952_20660	COG3254	rhamnose metabolic process
OM952_20665	COG0738	Major facilitator superfamily
OM952_20670	COG1414	Transcriptional regulator
OM952_20675	COG1917	Cupin 2, conserved barrel domain protein
OM952_20675	COG2207	Transcriptional regulator
OM952_20685	COG1971	Probably functions as a manganese efflux pump
OM952_20690	COG2205	protein histidine kinase activity
OM952_20700	COG3459	Glycosyltransferase 36 associated
OM952_20705	COG2211	Major facilitator Superfamily
OM952_20710	COG3265	gluconokinase activity
OM952_20715	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
OM952_20735	COG2911	Protein conserved in bacteria
OM952_20740	COG0729	surface antigen
OM952_20745	COG4771	TonB-dependent receptor
OM952_20750	COG0457	Tetratricopeptide repeat
OM952_20760	COG0752	glycyl-tRNA synthetase alpha subunit
OM952_20765	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
OM952_20780	COG0519	Catalyzes the synthesis of GMP from XMP
OM952_20780	COG0518	GMP synthase (glutamine-hydrolyzing) activity
OM952_20795	COG0805	protein transport
OM952_20800	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
OM952_20805	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
OM952_20815	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
OM952_20835	COG2974	May be involved in recombination
OM952_20840	COG0037	tRNA processing
OM952_20845	COG2115	Belongs to the xylose isomerase family
OM952_20855	COG3661	Belongs to the glycosyl hydrolase 67 family
OM952_20865	COG4948	Mandelate Racemase Muconate Lactonizing
OM952_20875	COG1472	Belongs to the glycosyl hydrolase 3 family
OM952_20880	COG0246	Mannitol dehydrogenase
OM952_20935	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
OM952_20960	COG3386	PFAM SMP-30 Gluconolaconase
OM952_20970	COG3250	beta-galactosidase activity
OM952_20975	COG1904	glucuronate isomerase
OM952_20980	COG3693	PFAM glycoside hydrolase, family 10
OM952_20995	COG3693	PFAM glycoside hydrolase, family 10
OM952_21010	COG2211	Major facilitator Superfamily
OM952_21090	COG2937	Belongs to the GPAT DAPAT family
OM952_21120	COG0284	orotidine-5'-phosphate decarboxylase activity
OM952_21125	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
OM952_21140	COG0635	Involved in the biosynthesis of porphyrin-containing compound
OM952_21190	COG0210	DNA helicase
OM952_21195	COG1435	thymidine kinase activity
OM952_21205	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
OM952_21215	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
OM952_21245	COG3135	benzoate transporter
OM952_21270	COG0676	glucose-6-phosphate 1-epimerase activity
OM952_21280	COG3012	SEC-C Motif Domain Protein
OM952_21320	COG3328	transposase activity
OM952_21335	COG0730	response to heat
OM952_21345	COG3328	transposase activity
OM952_21370	COG0302	gtp cyclohydrolase
OM952_21385	COG1566	PFAM secretion protein HlyD family protein
OM952_21395	COG1289	transmembrane transporter activity
OM952_21400	COG0477	Major facilitator Superfamily
OM952_21410	COG0583	DNA-binding transcription factor activity
OM952_21415	COG4221	oxidoreductase activity
OM952_21425	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OM952_21450	COG3328	transposase activity
OM952_21475	COG0564	pseudouridine synthase activity
OM952_21510	COG3012	SEC-C Motif Domain Protein
OM952_21580	COG4790	Type iii secretion
OM952_21700	COG3328	transposase activity
OM952_21740	COG3328	transposase activity
OM952_21755	COG3039	Transposase
OM952_21760	COG3328	transposase activity
OM952_21795	COG2801	Transposase and inactivated derivatives
OM952_21865	COG0439	Biotin carboxylase
OM952_21890	COG1028	Short-chain dehydrogenase reductase Sdr
OM952_21945	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
OM952_21950	COG1074	ATP-dependent DNA helicase activity
OM952_21955	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
OM952_21990	COG1127	ABC transporter
OM952_21995	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
OM952_22000	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
OM952_22015	COG2853	Lipoprotein
OM952_22025	COG0386	Belongs to the glutathione peroxidase family
OM952_22035	COG1322	Protein conserved in bacteria
OM952_22045	COG0583	DNA-binding transcription factor activity
OM952_22065	COG0531	amino acid
OM952_22070	COG3537	Alpha-1,2-mannosidase
OM952_22090	COG2199	diguanylate cyclase activity
OM952_22090	COG2203	Gaf domain
OM952_22095	COG3835	regulator
OM952_22100	COG1929	Belongs to the glycerate kinase type-1 family
OM952_22120	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
OM952_22125	COG0861	Integral membrane protein TerC family
OM952_22135	COG0584	glycerophosphoryl diester phosphodiesterase
OM952_22150	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
OM952_22155	COG0726	polysaccharide deacetylase
OM952_22165	COG0706	membrane insertase activity
OM952_22170	COG0594	ribonuclease P activity
OM952_22185	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OM952_22200	COG1487	ribonuclease activity
OM952_22205	COG4691	Plasmid stability protein
OM952_22210	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
OM952_22250	COG3328	transposase activity
OM952_22445	COG4962	Type ii secretion system protein e
OM952_22460	COG3451	type IV secretory pathway VirB4
OM952_22485	COG3846	protein secretion by the type IV secretion system
OM952_22520	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OM952_22550	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
OM952_22570	COG1487	ribonuclease activity
OM952_22575	COG4691	Plasmid stability protein
OM952_22580	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
OM952_22695	COG3039	Transposase