locus-tag	class	description
XppCFBP412P_00015	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XppCFBP412P_00020	COG1077	Cell shape determining protein MreB Mrl
XppCFBP412P_00025	COG1792	Involved in formation and maintenance of cell shape
XppCFBP412P_00040	COG0772	Belongs to the SEDS family
XppCFBP412P_00055	COG3039	Transposase
XppCFBP412P_00085	COG2951	lytic endotransglycosylase activity
XppCFBP412P_00090	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
XppCFBP412P_00095	COG1686	Belongs to the peptidase S11 family
XppCFBP412P_00105	COG2921	Belongs to the UPF0250 family
XppCFBP412P_00110	COG0321	lipoyl(octanoyl) transferase activity
XppCFBP412P_00115	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
XppCFBP412P_00140	COG1051	belongs to the nudix hydrolase family
XppCFBP412P_00140	COG1056	cytidyltransferase-related domain
XppCFBP412P_00175	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
XppCFBP412P_00180	COG0673	inositol 2-dehydrogenase activity
XppCFBP412P_00185	COG2823	Periplasmic or secreted lipoprotein
XppCFBP412P_00190	COG4251	negative regulation of phosphorylation
XppCFBP412P_00195	COG0784	Response regulator, receiver
XppCFBP412P_00200	COG4191	Histidine kinase
XppCFBP412P_00205	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
XppCFBP412P_00260	COG1459	type II secretion system
XppCFBP412P_00305	COG2188	Transcriptional regulator
XppCFBP412P_00315	COG1609	Transcriptional regulator
XppCFBP412P_00320	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
XppCFBP412P_00325	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
XppCFBP412P_00335	COG0617	tRNA 3'-terminal CCA addition
XppCFBP412P_00355	COG0525	valine-tRNA ligase activity
XppCFBP412P_00370	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
XppCFBP412P_00380	COG0795	lipopolysaccharide-transporting ATPase activity
XppCFBP412P_00395	COG4974	Belongs to the 'phage' integrase family
XppCFBP412P_00410	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
XppCFBP412P_00420	COG0047	phosphoribosylformylglycinamidine synthase activity
XppCFBP412P_00420	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
XppCFBP412P_00425	COG5295	Hep Hag repeat protein
XppCFBP412P_00430	COG1404	Belongs to the peptidase S8 family
XppCFBP412P_00435	COG5295	Hep Hag repeat protein
XppCFBP412P_00440	COG1404	Belongs to the peptidase S8 family
XppCFBP412P_00445	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
XppCFBP412P_00455	COG1459	type II secretion system
XppCFBP412P_00460	COG2165	general secretion pathway protein
XppCFBP412P_00465	COG4970	Tfp pilus assembly protein FimT
XppCFBP412P_00470	COG2165	general secretion pathway protein
XppCFBP412P_00475	COG4795	General secretion pathway protein
XppCFBP412P_00480	COG3156	type II secretion system protein K
XppCFBP412P_00485	COG3166	PFAM Fimbrial assembly family protein
XppCFBP412P_00500	COG1450	Type ii and iii secretion system protein
XppCFBP412P_00510	COG2188	Transcriptional regulator
XppCFBP412P_00590	COG1215	transferase activity, transferring glycosyl groups
XppCFBP412P_00595	COG1215	transferase activity, transferring glycosyl groups
XppCFBP412P_00600	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
XppCFBP412P_00625	COG0242	peptide deformylase activity
XppCFBP412P_00630	COG0488	(ABC) transporter
XppCFBP412P_00640	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
XppCFBP412P_00645	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
XppCFBP412P_00655	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
XppCFBP412P_00655	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
XppCFBP412P_00675	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
XppCFBP412P_00680	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
XppCFBP412P_00685	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
XppCFBP412P_00705	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
XppCFBP412P_00710	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
XppCFBP412P_00720	COG2205	protein histidine kinase activity
XppCFBP412P_00725	COG0745	RESPONSE REGULATOR receiver
XppCFBP412P_00735	COG0277	FAD linked oxidase domain protein
XppCFBP412P_00740	COG1988	membrane-bound metal-dependent
XppCFBP412P_00745	COG0792	nuclease activity
XppCFBP412P_00790	COG3116	cell division
XppCFBP412P_00800	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
XppCFBP412P_00805	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
XppCFBP412P_00810	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
XppCFBP412P_00820	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
XppCFBP412P_00825	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
XppCFBP412P_00830	COG1181	Belongs to the D-alanine--D-alanine ligase family
XppCFBP412P_00835	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
XppCFBP412P_00850	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
XppCFBP412P_00860	COG0739	heme binding
XppCFBP412P_00865	COG0653	protein targeting
XppCFBP412P_00870	COG0494	nUDIX hydrolase
XppCFBP412P_00880	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
XppCFBP412P_00890	COG0604	alcohol dehydrogenase
XppCFBP412P_00890	COG1028	Short-chain dehydrogenase reductase Sdr
XppCFBP412P_00890	COG3321	synthase
XppCFBP412P_00905	COG0366	Alpha amylase catalytic
XppCFBP412P_00935	COG2226	methyltransferase
XppCFBP412P_00940	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
XppCFBP412P_00950	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
XppCFBP412P_00990	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
XppCFBP412P_01000	COG4106	trans-aconitate 2-methyltransferase activity
XppCFBP412P_01005	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
XppCFBP412P_01020	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XppCFBP412P_01025	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
XppCFBP412P_01030	COG0667	Aldo Keto reductase
XppCFBP412P_01040	COG4771	TonB-dependent receptor
XppCFBP412P_01060	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XppCFBP412P_01065	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
XppCFBP412P_01075	COG2175	clavaminate synthase activity
XppCFBP412P_01085	COG4181	ATPase activity
XppCFBP412P_01100	COG0642	Histidine kinase
XppCFBP412P_01110	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
XppCFBP412P_01120	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
XppCFBP412P_01130	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
XppCFBP412P_01135	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
XppCFBP412P_01150	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
XppCFBP412P_01155	COG2967	ApaG domain
XppCFBP412P_01160	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
XppCFBP412P_01165	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
XppCFBP412P_01170	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
XppCFBP412P_01175	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
XppCFBP412P_01190	COG0123	including yeast histone deacetylase and acetoin utilization protein
XppCFBP412P_01195	COG2096	Adenosyltransferase
XppCFBP412P_01210	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XppCFBP412P_01215	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XppCFBP412P_01245	COG3384	dioxygenase
XppCFBP412P_01250	COG0583	DNA-binding transcription factor activity
XppCFBP412P_01255	COG0318	PFAM AMP-dependent synthetase and ligase
XppCFBP412P_01265	COG1024	Enoyl-CoA hydratase
XppCFBP412P_01285	COG3386	PFAM SMP-30 Gluconolaconase
XppCFBP412P_01295	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
XppCFBP412P_01315	COG0697	spore germination
XppCFBP412P_01325	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
XppCFBP412P_01350	COG2197	response regulator
XppCFBP412P_01360	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
XppCFBP412P_01375	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
XppCFBP412P_01380	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XppCFBP412P_01390	COG0583	DNA-binding transcription factor activity
XppCFBP412P_01395	COG3634	alkyl hydroperoxide reductase activity
XppCFBP412P_01405	COG2890	protein-(glutamine-N5) methyltransferase activity
XppCFBP412P_01425	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
XppCFBP412P_01425	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
XppCFBP412P_01465	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
XppCFBP412P_01485	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
XppCFBP412P_01490	COG1404	Belongs to the peptidase S8 family
XppCFBP412P_01495	COG1404	Belongs to the peptidase S8 family
XppCFBP412P_01500	COG1404	Belongs to the peptidase S8 family
XppCFBP412P_01505	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
XppCFBP412P_01530	COG1295	ribonuclease BN
XppCFBP412P_01535	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XppCFBP412P_01540	COG1254	Belongs to the acylphosphatase family
XppCFBP412P_01555	COG0521	Mo-molybdopterin cofactor biosynthetic process
XppCFBP412P_01565	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
XppCFBP412P_01570	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
XppCFBP412P_01580	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
XppCFBP412P_01585	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
XppCFBP412P_01595	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
XppCFBP412P_01600	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
XppCFBP412P_01605	COG0193	aminoacyl-tRNA hydrolase activity
XppCFBP412P_01610	COG0012	GTP binding
XppCFBP412P_01630	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
XppCFBP412P_01645	COG0250	Participates in transcription elongation, termination and antitermination
XppCFBP412P_01650	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
XppCFBP412P_01655	COG0081	regulation of translation
XppCFBP412P_01660	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
XppCFBP412P_01670	COG0085	RNA polymerase activity
XppCFBP412P_01675	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
XppCFBP412P_01680	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
XppCFBP412P_01685	COG0049	tRNA binding
XppCFBP412P_01690	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
XppCFBP412P_01695	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
XppCFBP412P_01710	COG3328	transposase activity
XppCFBP412P_01715	COG0051	transcription antitermination factor activity, RNA binding
XppCFBP412P_01720	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
XppCFBP412P_01725	COG0088	Forms part of the polypeptide exit tunnel
XppCFBP412P_01730	COG0089	rRNA binding
XppCFBP412P_01735	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
XppCFBP412P_01740	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
XppCFBP412P_01750	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
XppCFBP412P_01755	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
XppCFBP412P_01760	COG0255	Belongs to the universal ribosomal protein uL29 family
XppCFBP412P_01765	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
XppCFBP412P_01775	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
XppCFBP412P_01780	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
XppCFBP412P_01790	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
XppCFBP412P_01795	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
XppCFBP412P_01800	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
XppCFBP412P_01810	COG1841	ribosomal large subunit assembly
XppCFBP412P_01815	COG0200	Binds to the 23S rRNA
XppCFBP412P_01820	COG0201	protein transport
XppCFBP412P_01845	COG0203	ribosomal protein L17
XppCFBP412P_01850	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
XppCFBP412P_01870	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
XppCFBP412P_01880	COG0154	amidase activity
XppCFBP412P_01890	COG1217	gtp-binding protein TYPA
XppCFBP412P_01895	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
XppCFBP412P_01900	COG0039	L-malate dehydrogenase activity
XppCFBP412P_01905	COG0625	glutathione transferase activity
XppCFBP412P_01925	COG0446	pyridine nucleotide-disulphide oxidoreductase
XppCFBP412P_01925	COG1902	pentaerythritol trinitrate reductase activity
XppCFBP412P_01930	COG0604	alcohol dehydrogenase
XppCFBP412P_01940	COG3039	Transposase
XppCFBP412P_01945	COG2885	chlorophyll binding
XppCFBP412P_01965	COG0156	8-amino-7-oxononanoate synthase activity
XppCFBP412P_01970	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
XppCFBP412P_01975	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
XppCFBP412P_01980	COG4208	sulfate ABC transporter
XppCFBP412P_01985	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
XppCFBP412P_02015	COG0406	alpha-ribazole phosphatase activity
XppCFBP412P_02025	COG0285	dihydrofolate synthase activity
XppCFBP412P_02045	COG2833	Protein of unknown function (DUF455)
XppCFBP412P_02065	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XppCFBP412P_02070	COG0671	phosphoesterase, PA-phosphatase related
XppCFBP412P_02075	COG0438	transferase activity, transferring glycosyl groups
XppCFBP412P_02085	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
XppCFBP412P_02100	COG4783	chaperone-mediated protein folding
XppCFBP412P_02115	COG0473	3-isopropylmalate dehydrogenase activity
XppCFBP412P_02155	COG3328	transposase activity
XppCFBP412P_02170	COG0544	peptidyl-prolyl cis-trans isomerase activity
XppCFBP412P_02180	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
XppCFBP412P_02210	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
XppCFBP412P_02220	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XppCFBP412P_02230	COG0328	RNA-DNA hybrid ribonuclease activity
XppCFBP412P_02235	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
XppCFBP412P_02240	COG0631	protein serine/threonine phosphatase activity
XppCFBP412P_02265	COG0859	PFAM glycosyl transferase family 9
XppCFBP412P_02270	COG3642	lipopolysaccharide core region biosynthetic process
XppCFBP412P_02275	COG1234	tRNA 3'-trailer cleavage
XppCFBP412P_02280	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
XppCFBP412P_02290	COG0315	cyclic pyranopterin monophosphate synthase activity
XppCFBP412P_02295	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
XppCFBP412P_02300	COG0314	molybdopterin synthase activity
XppCFBP412P_02320	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
XppCFBP412P_02325	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
XppCFBP412P_02330	COG0537	adenosine 5'-monophosphoramidase activity
XppCFBP412P_02350	COG0714	Associated with various cellular activities
XppCFBP412P_02365	COG0424	maF-like protein
XppCFBP412P_02370	COG1399	metal-binding, possibly nucleic acid-binding protein
XppCFBP412P_02375	COG0333	Belongs to the bacterial ribosomal protein bL32 family
XppCFBP412P_02380	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XppCFBP412P_02395	COG1028	Short-chain dehydrogenase reductase Sdr
XppCFBP412P_02410	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
XppCFBP412P_02415	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
XppCFBP412P_02450	COG3829	transcription factor binding
XppCFBP412P_02500	COG2373	Large extracellular alpha-helical protein
XppCFBP412P_02520	COG3852	Histidine kinase
XppCFBP412P_02525	COG4953	penicillin-binding protein 1C
XppCFBP412P_02535	COG0678	peroxiredoxin activity
XppCFBP412P_02555	COG0330	HflC and HflK could
XppCFBP412P_02560	COG0330	HflC and HflK could
XppCFBP412P_02570	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
XppCFBP412P_02575	COG0308	aminopeptidase N
XppCFBP412P_02585	COG1028	Short-chain dehydrogenase reductase Sdr
XppCFBP412P_02590	COG1309	transcriptional regulator
XppCFBP412P_02650	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
XppCFBP412P_02660	COG3387	PFAM Glycoside hydrolase 15-related
XppCFBP412P_02665	COG1028	Short-chain dehydrogenase reductase Sdr
XppCFBP412P_02675	COG3537	Alpha-1,2-mannosidase
XppCFBP412P_02695	COG0492	ferredoxin-NADP+ reductase activity
XppCFBP412P_02725	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XppCFBP412P_02730	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
XppCFBP412P_02735	COG2080	2 iron, 2 sulfur cluster binding
XppCFBP412P_02770	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
XppCFBP412P_02785	COG0587	DNA-directed DNA polymerase activity
XppCFBP412P_02805	COG1297	OPT oligopeptide transporter protein
XppCFBP412P_02825	COG0823	Involved in the tonB-independent uptake of proteins
XppCFBP412P_02825	COG1506	peptidase
XppCFBP412P_02855	COG2207	Transcriptional regulator
XppCFBP412P_02855	COG1917	Cupin 2, conserved barrel domain protein
XppCFBP412P_02860	COG3328	transposase activity
XppCFBP412P_02865	COG0753	catalase activity
XppCFBP412P_02870	COG0656	L-ascorbic acid biosynthetic process
XppCFBP412P_02880	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
XppCFBP412P_02880	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
XppCFBP412P_02905	COG2814	Major facilitator Superfamily
XppCFBP412P_02935	COG2194	sulfuric ester hydrolase activity
XppCFBP412P_02950	COG0745	RESPONSE REGULATOR receiver
XppCFBP412P_02955	COG0642	Histidine kinase
XppCFBP412P_02965	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
XppCFBP412P_02970	COG2894	cell division
XppCFBP412P_02975	COG0850	regulation of cytokinetic process
XppCFBP412P_02990	COG4585	Histidine kinase
XppCFBP412P_02995	COG2197	response regulator
XppCFBP412P_03010	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
XppCFBP412P_03035	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
XppCFBP412P_03045	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
XppCFBP412P_03060	COG1595	DNA-templated transcription, initiation
XppCFBP412P_03070	COG1946	Acyl-CoA thioesterase
XppCFBP412P_03085	COG0824	Thioesterase
XppCFBP412P_03090	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
XppCFBP412P_03095	COG0261	This protein binds to 23S rRNA in the presence of protein L20
XppCFBP412P_03100	COG0211	Belongs to the bacterial ribosomal protein bL27 family
XppCFBP412P_03105	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
XppCFBP412P_03110	COG0268	Binds directly to 16S ribosomal RNA
XppCFBP412P_03120	COG0196	riboflavin kinase activity
XppCFBP412P_03125	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
XppCFBP412P_03130	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
XppCFBP412P_03135	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
XppCFBP412P_03150	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
XppCFBP412P_03155	COG1845	cytochrome c oxidase, subunit III
XppCFBP412P_03160	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
XppCFBP412P_03175	COG3152	Membrane
XppCFBP412P_03185	COG2207	Transcriptional regulator
XppCFBP412P_03190	COG0326	Molecular chaperone. Has ATPase activity
XppCFBP412P_03200	COG1366	Belongs to the anti-sigma-factor antagonist family
XppCFBP412P_03205	COG1366	Belongs to the anti-sigma-factor antagonist family
XppCFBP412P_03235	COG4771	TonB-dependent receptor
XppCFBP412P_03245	COG5507	3-demethylubiquinone-9 3-methyltransferase
XppCFBP412P_03250	COG2205	protein histidine kinase activity
XppCFBP412P_03260	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
XppCFBP412P_03265	COG2205	protein histidine kinase activity
XppCFBP412P_03265	COG4999	Histidine kinase
XppCFBP412P_03265	COG3850	Histidine kinase
XppCFBP412P_03265	COG3437	response regulator, receiver
XppCFBP412P_03270	COG0784	Response regulator, receiver
XppCFBP412P_03270	COG4191	Histidine kinase
XppCFBP412P_03295	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
XppCFBP412P_03305	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
XppCFBP412P_03310	COG0228	four-way junction DNA binding
XppCFBP412P_03315	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
XppCFBP412P_03320	COG0336	Belongs to the RNA methyltransferase TrmD family
XppCFBP412P_03325	COG0335	large ribosomal subunit rRNA binding
XppCFBP412P_03330	COG0534	Mate efflux family protein
XppCFBP412P_03355	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
XppCFBP412P_03365	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
XppCFBP412P_03405	COG3250	beta-galactosidase activity
XppCFBP412P_03410	COG3867	Arabinogalactan endo-beta-1,4-galactanase
XppCFBP412P_03430	COG1960	acyl-CoA dehydrogenase activity
XppCFBP412P_03460	COG0457	Tetratricopeptide repeat
XppCFBP412P_03470	COG0457	Tetratricopeptide repeat
XppCFBP412P_03480	COG1024	Enoyl-CoA hydratase
XppCFBP412P_03480	COG1250	3-hydroxyacyl-CoA dehydrogenase
XppCFBP412P_03495	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XppCFBP412P_03500	COG0481	GTPase activity
XppCFBP412P_03515	COG0571	ribonuclease III activity
XppCFBP412P_03520	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
XppCFBP412P_03525	COG1381	Involved in DNA repair and RecF pathway recombination
XppCFBP412P_03535	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
XppCFBP412P_03540	COG2954	triphosphatase activity
XppCFBP412P_03545	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
XppCFBP412P_03550	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
XppCFBP412P_03555	COG3046	protein related to deoxyribodipyrimidine photolyase
XppCFBP412P_03560	COG1472	Belongs to the glycosyl hydrolase 3 family
XppCFBP412P_03565	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
XppCFBP412P_03570	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
XppCFBP412P_03575	COG1278	Cold shock
XppCFBP412P_03580	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XppCFBP412P_03590	COG1201	RNA secondary structure unwinding
XppCFBP412P_03595	COG1793	dna ligase
XppCFBP412P_03605	COG1793	dna ligase
XppCFBP412P_03605	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
XppCFBP412P_03645	COG0183	Belongs to the thiolase family
XppCFBP412P_03665	COG1451	nucleotide metabolic process
XppCFBP412P_03670	COG5487	UPF0391 membrane protein
XppCFBP412P_03680	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
XppCFBP412P_03700	COG1077	Cell shape determining protein MreB Mrl
XppCFBP412P_03705	COG1047	Peptidyl-prolyl cis-trans
XppCFBP412P_03715	COG2824	Alkylphosphonate utilization operon protein PhnA
XppCFBP412P_03725	COG1902	pentaerythritol trinitrate reductase activity
XppCFBP412P_03730	COG2814	Major facilitator Superfamily
XppCFBP412P_03760	COG0392	lysyltransferase activity
XppCFBP412P_03760	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
XppCFBP412P_03770	COG0251	oxidation-reduction process
XppCFBP412P_03775	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
XppCFBP412P_03790	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
XppCFBP412P_03815	COG1595	DNA-templated transcription, initiation
XppCFBP412P_03830	COG2878	Part of a membrane complex involved in electron transport
XppCFBP412P_03840	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
XppCFBP412P_03840	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
XppCFBP412P_03860	COG0346	lactoylglutathione lyase activity
XppCFBP412P_03875	COG0833	amino acid
XppCFBP412P_03880	COG2040	homocysteine
XppCFBP412P_03890	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
XppCFBP412P_03910	COG1695	Transcriptional regulator
XppCFBP412P_03930	COG1981	membrane
XppCFBP412P_03945	COG0825	malonyl-CoA metabolic process
XppCFBP412P_03960	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XppCFBP412P_03965	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XppCFBP412P_03970	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
XppCFBP412P_03975	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XppCFBP412P_03990	COG0750	zinc metalloprotease
XppCFBP412P_03995	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
XppCFBP412P_04000	COG0575	Belongs to the CDS family
XppCFBP412P_04005	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
XppCFBP412P_04010	COG0233	cytoplasmic translational termination
XppCFBP412P_04015	COG0528	UMP kinase activity
XppCFBP412P_04025	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
XppCFBP412P_04030	COG0052	Belongs to the universal ribosomal protein uS2 family
XppCFBP412P_04070	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
XppCFBP412P_04080	COG1393	Belongs to the ArsC family
XppCFBP412P_04085	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XppCFBP412P_04090	COG0367	asparagine synthase
XppCFBP412P_04100	COG4774	siderophore transport
XppCFBP412P_04155	COG3328	transposase activity
XppCFBP412P_04190	COG1566	PFAM secretion protein HlyD family protein
XppCFBP412P_04195	COG2814	Major facilitator Superfamily
XppCFBP412P_04225	COG3104	oligopeptide transport
XppCFBP412P_04255	COG0339	signal peptide processing
XppCFBP412P_04260	COG0386	Belongs to the glutathione peroxidase family
XppCFBP412P_04320	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
XppCFBP412P_04325	COG0084	hydrolase, TatD family'
XppCFBP412P_04340	COG1960	acyl-CoA dehydrogenase activity
XppCFBP412P_04360	COG0367	asparagine synthase
XppCFBP412P_04370	COG0305	Participates in initiation and elongation during chromosome replication
XppCFBP412P_04375	COG0415	Belongs to the DNA photolyase family
XppCFBP412P_04385	COG0583	DNA-binding transcription factor activity
XppCFBP412P_04430	COG3706	GGDEF domain
XppCFBP412P_04450	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
XppCFBP412P_04465	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XppCFBP412P_04475	COG0497	DNA recombination
XppCFBP412P_04480	COG1420	regulation of RNA biosynthetic process
XppCFBP412P_04485	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
XppCFBP412P_04490	COG0443	Heat shock 70 kDa protein
XppCFBP412P_04495	COG0484	heat shock protein binding
XppCFBP412P_04500	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
XppCFBP412P_04530	COG0583	DNA-binding transcription factor activity
XppCFBP412P_04535	COG1132	(ABC) transporter
XppCFBP412P_04570	COG2850	peptidyl-arginine hydroxylation
XppCFBP412P_04590	COG1253	flavin adenine dinucleotide binding
XppCFBP412P_04625	COG1131	(ABC) transporter
XppCFBP412P_04630	COG1725	Transcriptional regulator
XppCFBP412P_04640	COG0386	Belongs to the glutathione peroxidase family
XppCFBP412P_04660	COG2900	Belongs to the SlyX family
XppCFBP412P_04690	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XppCFBP412P_04700	COG1410	methionine synthase
XppCFBP412P_04700	COG0646	methionine synthase
XppCFBP412P_04705	COG0646	methionine synthase
XppCFBP412P_04705	COG1410	methionine synthase
XppCFBP412P_04710	COG2226	methyltransferase
XppCFBP412P_04715	COG1960	acyl-CoA dehydrogenase activity
XppCFBP412P_04720	COG1960	acyl-CoA dehydrogenase activity
XppCFBP412P_04735	COG0557	exoribonuclease II activity
XppCFBP412P_04745	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
XppCFBP412P_04760	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
XppCFBP412P_04770	COG0704	Plays a role in the regulation of phosphate uptake
XppCFBP412P_04775	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
XppCFBP412P_04780	COG0581	inorganic phosphate transmembrane transporter activity
XppCFBP412P_04785	COG0573	inorganic phosphate transmembrane transporter activity
XppCFBP412P_04790	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
XppCFBP412P_04815	COG0659	secondary active sulfate transmembrane transporter activity
XppCFBP412P_04820	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
XppCFBP412P_04830	COG1024	Enoyl-CoA hydratase
XppCFBP412P_04840	COG0494	nUDIX hydrolase
XppCFBP412P_04875	COG0488	(ABC) transporter
XppCFBP412P_04885	COG0116	Belongs to the methyltransferase superfamily
XppCFBP412P_04885	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
XppCFBP412P_04890	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
XppCFBP412P_04910	COG2925	Exonuclease
XppCFBP412P_04920	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XppCFBP412P_04925	COG3844	kynureninase activity
XppCFBP412P_04935	COG0662	Cupin 2, conserved barrel domain protein
XppCFBP412P_04940	COG0288	reversible hydration of carbon dioxide
XppCFBP412P_05020	COG0017	Asparaginyl-tRNA synthetase
XppCFBP412P_05030	COG0316	Belongs to the HesB IscA family
XppCFBP412P_05035	COG0360	Binds together with S18 to 16S ribosomal RNA
XppCFBP412P_05040	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
XppCFBP412P_05045	COG0359	binds to the 23S rRNA
XppCFBP412P_05055	COG3115	cell septum assembly
XppCFBP412P_05065	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XppCFBP412P_05070	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
XppCFBP412P_05075	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
XppCFBP412P_05090	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
XppCFBP412P_05100	COG4993	Dehydrogenase
XppCFBP412P_05110	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
XppCFBP412P_05125	COG2986	histidine ammonia-lyase
XppCFBP412P_05130	COG1228	amidohydrolase
XppCFBP412P_05170	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
XppCFBP412P_05175	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
XppCFBP412P_05180	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
XppCFBP412P_05185	COG0077	Prephenate dehydratase
XppCFBP412P_05185	COG1605	Chorismate mutase
XppCFBP412P_05190	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
XppCFBP412P_05205	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
XppCFBP412P_05210	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
XppCFBP412P_05215	COG0583	DNA-binding transcription factor activity
XppCFBP412P_05240	COG0840	transmembrane signaling receptor activity
XppCFBP412P_05260	COG0784	Response regulator, receiver
XppCFBP412P_05260	COG4191	Histidine kinase
XppCFBP412P_05270	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
XppCFBP412P_05290	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XppCFBP412P_05300	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
XppCFBP412P_05310	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
XppCFBP412P_05325	COG1595	DNA-templated transcription, initiation
XppCFBP412P_05380	COG2244	polysaccharide biosynthetic process
XppCFBP412P_05410	COG2264	protein methyltransferase activity
XppCFBP412P_05420	COG0438	transferase activity, transferring glycosyl groups
XppCFBP412P_05435	COG1136	(ABC) transporter
XppCFBP412P_05445	COG0477	Major facilitator Superfamily
XppCFBP412P_05450	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XppCFBP412P_05465	COG1253	flavin adenine dinucleotide binding
XppCFBP412P_05480	COG0306	phosphate transporter
XppCFBP412P_05505	COG0504	CTP synthase activity
XppCFBP412P_05510	COG2877	3-deoxy-8-phosphooctulonate synthase activity
XppCFBP412P_05520	COG0148	phosphopyruvate hydratase activity
XppCFBP412P_05525	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
XppCFBP412P_05535	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
XppCFBP412P_05540	COG0585	pseudouridine synthase activity
XppCFBP412P_05545	COG2840	Smr protein MutS2
XppCFBP412P_05550	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
XppCFBP412P_05555	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
XppCFBP412P_05560	COG1238	metal cluster binding
XppCFBP412P_05570	COG3737	Protein of unknown function (DUF498/DUF598)
XppCFBP412P_05575	COG1534	Rna-binding protein
XppCFBP412P_05580	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
XppCFBP412P_05590	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
XppCFBP412P_05595	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
XppCFBP412P_05605	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
XppCFBP412P_05610	COG1546	Belongs to the CinA family
XppCFBP412P_05620	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
XppCFBP412P_05625	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
XppCFBP412P_05635	COG2137	regulation of response to DNA damage stimulus
XppCFBP412P_05640	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
XppCFBP412P_05645	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
XppCFBP412P_05670	COG0583	DNA-binding transcription factor activity
XppCFBP412P_05695	COG0351	phosphomethylpyrimidine kinase
XppCFBP412P_05710	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
XppCFBP412P_05715	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
XppCFBP412P_05730	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
XppCFBP412P_05740	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
XppCFBP412P_05745	COG3734	2-keto-3-deoxy-galactonokinase
XppCFBP412P_05755	COG4948	Mandelate Racemase Muconate Lactonizing
XppCFBP412P_05760	COG0800	Aldolase
XppCFBP412P_05800	COG1501	Belongs to the glycosyl hydrolase 31 family
XppCFBP412P_05810	COG1070	Carbohydrate kinase
XppCFBP412P_05815	COG2115	Belongs to the xylose isomerase family
XppCFBP412P_05820	COG0477	Major facilitator Superfamily
XppCFBP412P_05840	COG0860	N-Acetylmuramoyl-L-alanine amidase
XppCFBP412P_05845	COG1469	GTP cyclohydrolase I activity
XppCFBP412P_05870	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
XppCFBP412P_05875	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
XppCFBP412P_05880	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
XppCFBP412P_05885	COG0166	Belongs to the GPI family
XppCFBP412P_05905	COG1472	Belongs to the glycosyl hydrolase 3 family
XppCFBP412P_05920	COG2203	Gaf domain
XppCFBP412P_05920	COG5001	Diguanylate cyclase
XppCFBP412P_05920	COG4251	negative regulation of phosphorylation
XppCFBP412P_05920	COG3706	GGDEF domain
XppCFBP412P_05925	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XppCFBP412P_05930	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
XppCFBP412P_05940	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
XppCFBP412P_05945	COG0671	phosphoesterase, PA-phosphatase related
XppCFBP412P_05955	COG1794	racemase activity, acting on amino acids and derivatives
XppCFBP412P_05960	COG0697	spore germination
XppCFBP412P_05965	COG0812	UDP-N-acetylmuramate dehydrogenase activity
XppCFBP412P_05970	COG0167	dihydroorotate dehydrogenase activity
XppCFBP412P_05990	COG1012	belongs to the aldehyde dehydrogenase family
XppCFBP412P_06005	COG3328	transposase activity
XppCFBP412P_06010	COG0366	Alpha amylase catalytic
XppCFBP412P_06030	COG1082	Xylose isomerase domain protein TIM barrel
XppCFBP412P_06040	COG2211	Major facilitator Superfamily
XppCFBP412P_06055	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
XppCFBP412P_06060	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
XppCFBP412P_06075	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
XppCFBP412P_06080	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
XppCFBP412P_06080	COG0072	phenylalanine-tRNA ligase activity
XppCFBP412P_06130	COG0438	transferase activity, transferring glycosyl groups
XppCFBP412P_06135	COG0438	transferase activity, transferring glycosyl groups
XppCFBP412P_06145	COG0438	transferase activity, transferring glycosyl groups
XppCFBP412P_06170	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XppCFBP412P_06180	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XppCFBP412P_06200	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
XppCFBP412P_06210	COG1960	acyl-CoA dehydrogenase activity
XppCFBP412P_06220	COG3040	lipid binding
XppCFBP412P_06235	COG0322	excinuclease ABC activity
XppCFBP412P_06250	COG0784	Response regulator, receiver
XppCFBP412P_06250	COG4191	Histidine kinase
XppCFBP412P_06270	COG1194	a g-specific adenine glycosylase
XppCFBP412P_06280	COG0552	protein localization to endoplasmic reticulum
XppCFBP412P_06290	COG3938	Belongs to the proline racemase family
XppCFBP412P_06295	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XppCFBP412P_06310	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
XppCFBP412P_06320	COG0006	proline dipeptidase activity
XppCFBP412P_06335	COG0531	amino acid
XppCFBP412P_06450	COG3328	transposase activity
XppCFBP412P_06465	COG3328	transposase activity
XppCFBP412P_06495	COG3328	transposase activity
XppCFBP412P_06500	COG0460	homoserine dehydrogenase
XppCFBP412P_06500	COG0527	aspartate kinase activity
XppCFBP412P_06535	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XppCFBP412P_06540	COG0124	histidyl-tRNA synthetase
XppCFBP412P_06550	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
XppCFBP412P_06555	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
XppCFBP412P_06560	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XppCFBP412P_06565	COG0131	Imidazoleglycerol-phosphate dehydratase
XppCFBP412P_06565	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
XppCFBP412P_06570	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
XppCFBP412P_06575	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
XppCFBP412P_06580	COG0107	imidazoleglycerol-phosphate synthase activity
XppCFBP412P_06585	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
XppCFBP412P_06585	COG0140	phosphoribosyl-ATP diphosphatase activity
XppCFBP412P_06600	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
XppCFBP412P_06605	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
XppCFBP412P_06610	COG0235	Class ii aldolase
XppCFBP412P_06615	COG0531	amino acid
XppCFBP412P_06620	COG0531	amino acid
XppCFBP412P_06630	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
XppCFBP412P_06635	COG0277	FAD linked oxidase domain protein
XppCFBP412P_06655	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
XppCFBP412P_06700	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
XppCFBP412P_06705	COG2258	MOSC domain
XppCFBP412P_06710	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
XppCFBP412P_06715	COG0505	Belongs to the CarA family
XppCFBP412P_06725	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
XppCFBP412P_06730	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XppCFBP412P_06740	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
XppCFBP412P_06760	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
XppCFBP412P_06770	COG0784	Response regulator, receiver
XppCFBP412P_06770	COG2198	Histidine kinase
XppCFBP412P_06770	COG2205	protein histidine kinase activity
XppCFBP412P_06775	COG0784	Response regulator, receiver
XppCFBP412P_06775	COG2198	Histidine kinase
XppCFBP412P_06775	COG2205	protein histidine kinase activity
XppCFBP412P_06780	COG1024	Enoyl-CoA hydratase
XppCFBP412P_06785	COG0318	PFAM AMP-dependent synthetase and ligase
XppCFBP412P_06820	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XppCFBP412P_06830	COG2201	protein-glutamate methylesterase activity
XppCFBP412P_06835	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
XppCFBP412P_06845	COG0840	transmembrane signaling receptor activity
XppCFBP412P_06855	COG0835	chemotaxis
XppCFBP412P_06870	COG0840	transmembrane signaling receptor activity
XppCFBP412P_06875	COG0840	transmembrane signaling receptor activity
XppCFBP412P_06880	COG0840	transmembrane signaling receptor activity
XppCFBP412P_06885	COG0840	transmembrane signaling receptor activity
XppCFBP412P_06890	COG0840	transmembrane signaling receptor activity
XppCFBP412P_06905	COG0840	transmembrane signaling receptor activity
XppCFBP412P_06910	COG0840	transmembrane signaling receptor activity
XppCFBP412P_06915	COG0840	transmembrane signaling receptor activity
XppCFBP412P_06920	COG0840	transmembrane signaling receptor activity
XppCFBP412P_06935	COG0840	transmembrane signaling receptor activity
XppCFBP412P_06950	COG0840	transmembrane signaling receptor activity
XppCFBP412P_06955	COG0840	transmembrane signaling receptor activity
XppCFBP412P_06965	COG0745	RESPONSE REGULATOR receiver
XppCFBP412P_06975	COG0835	chemotaxis
XppCFBP412P_06980	COG1192	Involved in chromosome partitioning
XppCFBP412P_06985	COG1360	Flagellar Motor Protein
XppCFBP412P_06990	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
XppCFBP412P_07025	COG3328	transposase activity
XppCFBP412P_07030	COG0643	Histidine kinase
XppCFBP412P_07030	COG0784	Response regulator, receiver
XppCFBP412P_07030	COG2198	Histidine kinase
XppCFBP412P_07060	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
XppCFBP412P_07085	COG3039	Transposase
XppCFBP412P_07095	COG1684	flagellar biosynthetic protein fliR
XppCFBP412P_07115	COG3190	flagellar
XppCFBP412P_07165	COG1677	Flagellar hook-basal body complex protein FliE
XppCFBP412P_07220	COG1028	Short-chain dehydrogenase reductase Sdr
XppCFBP412P_07225	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XppCFBP412P_07245	COG2201	protein-glutamate methylesterase activity
XppCFBP412P_07275	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
XppCFBP412P_07285	COG3039	Transposase
XppCFBP412P_07290	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
XppCFBP412P_07300	COG3951	Flagellar rod assembly protein muramidase FlgJ
XppCFBP412P_07300	COG1705	Flagellar rod assembly protein muramidase FlgJ
XppCFBP412P_07305	COG1706	bacterial-type flagellum-dependent cell motility
XppCFBP412P_07310	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
XppCFBP412P_07320	COG4787	bacterial-type flagellum-dependent cell motility
XppCFBP412P_07330	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
XppCFBP412P_07335	COG1558	bacterial-type flagellum-dependent cell motility
XppCFBP412P_07345	COG0835	chemotaxis
XppCFBP412P_07345	COG0784	Response regulator, receiver
XppCFBP412P_07365	COG5002	protein histidine kinase activity
XppCFBP412P_07375	COG4585	Histidine kinase
XppCFBP412P_07395	COG2915	High frequency lysogenization protein hflD homolog
XppCFBP412P_07400	COG0482	sulfurtransferase activity
XppCFBP412P_07415	COG0542	response to heat
XppCFBP412P_07425	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
XppCFBP412P_07435	COG0492	ferredoxin-NADP+ reductase activity
XppCFBP412P_07440	COG1674	ftsk spoiiie
XppCFBP412P_07450	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
XppCFBP412P_07460	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
XppCFBP412P_07465	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
XppCFBP412P_07470	COG0183	Belongs to the thiolase family
XppCFBP412P_07475	COG1250	3-hydroxyacyl-CoA dehydrogenase
XppCFBP412P_07475	COG1024	Enoyl-CoA hydratase
XppCFBP412P_07490	COG0820	rRNA (adenine-C2-)-methyltransferase activity
XppCFBP412P_07510	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XppCFBP412P_07515	COG1160	GTP binding
XppCFBP412P_07520	COG0303	'Molybdopterin
XppCFBP412P_07525	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
XppCFBP412P_07560	COG0708	Exodeoxyribonuclease III
XppCFBP412P_07570	COG0303	'Molybdopterin
XppCFBP412P_07575	COG0746	molybdenum cofactor guanylyltransferase activity
XppCFBP412P_07600	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
XppCFBP412P_07600	COG1648	precorrin-2 dehydrogenase activity
XppCFBP412P_07610	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
XppCFBP412P_07615	COG2223	nitrite transmembrane transporter activity
XppCFBP412P_07620	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
XppCFBP412P_07630	COG0243	molybdopterin cofactor binding
XppCFBP412P_07645	COG3685	Protein conserved in bacteria
XppCFBP412P_07665	COG5001	Diguanylate cyclase
XppCFBP412P_07675	COG4566	intracellular signal transduction
XppCFBP412P_07730	COG3328	transposase activity
XppCFBP412P_07810	COG3039	Transposase
XppCFBP412P_07820	COG3328	transposase activity
XppCFBP412P_07830	COG1073	alpha beta
XppCFBP412P_07830	COG2226	methyltransferase
XppCFBP412P_07845	COG0363	glucosamine-6-phosphate deaminase activity
XppCFBP412P_07885	COG1309	transcriptional regulator
XppCFBP412P_07900	COG2154	pterin-4-alpha-carbinolamine dehydratase
XppCFBP412P_07910	COG0428	transporter
XppCFBP412P_07915	COG3064	Membrane
XppCFBP412P_07925	COG1530	ribonuclease E activity
XppCFBP412P_07930	COG3039	Transposase
XppCFBP412P_07940	COG1054	Belongs to the UPF0176 family
XppCFBP412P_07960	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
XppCFBP412P_07985	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
XppCFBP412P_07990	COG0322	excinuclease ABC activity
XppCFBP412P_08000	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
XppCFBP412P_08005	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
XppCFBP412P_08010	COG1663	tetraacyldisaccharide 4'-kinase activity
XppCFBP412P_08015	COG1132	(ABC) transporter
XppCFBP412P_08025	COG0811	peptide transport
XppCFBP412P_08040	COG1136	(ABC) transporter
XppCFBP412P_08045	COG4591	ABC-type transport system involved in lipoprotein release permease component
XppCFBP412P_08055	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
XppCFBP412P_08060	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
XppCFBP412P_08075	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
XppCFBP412P_08090	COG0354	folic acid binding
XppCFBP412P_08100	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
XppCFBP412P_08105	COG0837	glucose binding
XppCFBP412P_08110	COG0363	glucosamine-6-phosphate deaminase activity
XppCFBP412P_08115	COG0129	dihydroxy-acid dehydratase activity
XppCFBP412P_08120	COG0800	Aldolase
XppCFBP412P_08185	COG0784	Response regulator, receiver
XppCFBP412P_08185	COG2205	protein histidine kinase activity
XppCFBP412P_08190	COG2183	response to ionizing radiation
XppCFBP412P_08200	COG0723	plastoquinol--plastocyanin reductase activity
XppCFBP412P_08200	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XppCFBP412P_08215	COG3243	poly(R)-hydroxyalkanoic acid synthase
XppCFBP412P_08225	COG1183	phosphatidylcholine synthase activity
XppCFBP412P_08230	COG1028	Short-chain dehydrogenase reductase Sdr
XppCFBP412P_08245	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
XppCFBP412P_08260	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
XppCFBP412P_08275	COG1914	H( )-stimulated, divalent metal cation uptake system
XppCFBP412P_08295	COG2814	Major facilitator Superfamily
XppCFBP412P_08310	COG1335	isochorismatase
XppCFBP412P_08330	COG2197	response regulator
XppCFBP412P_08360	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
XppCFBP412P_08365	COG3002	Belongs to the UPF0753 family
XppCFBP412P_08375	COG0604	alcohol dehydrogenase
XppCFBP412P_08380	COG3384	dioxygenase
XppCFBP412P_08395	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
XppCFBP412P_08410	COG0583	DNA-binding transcription factor activity
XppCFBP412P_08455	COG0519	Catalyzes the synthesis of GMP from XMP
XppCFBP412P_08455	COG0518	GMP synthase (glutamine-hydrolyzing) activity
XppCFBP412P_08465	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
XppCFBP412P_08475	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
XppCFBP412P_08475	COG0475	glutathione-regulated potassium exporter activity
XppCFBP412P_08480	COG1210	Utp--glucose-1-phosphate uridylyltransferase
XppCFBP412P_08490	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
XppCFBP412P_08495	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
XppCFBP412P_08505	COG0776	regulation of translation
XppCFBP412P_08510	COG0539	negative regulation of cytoplasmic translation
XppCFBP412P_08515	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
XppCFBP412P_08530	COG2957	Belongs to the agmatine deiminase family
XppCFBP412P_08535	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XppCFBP412P_08560	COG0395	ABC-type sugar transport system, permease component
XppCFBP412P_08565	COG1175	transmembrane transport
XppCFBP412P_08600	COG2350	Protein conserved in bacteria
XppCFBP412P_08605	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
XppCFBP412P_08610	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
XppCFBP412P_08615	COG1187	pseudouridine synthase activity
XppCFBP412P_08630	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XppCFBP412P_08635	COG0436	Aminotransferase
XppCFBP412P_08640	COG4133	protoheme IX ABC transporter activity
XppCFBP412P_08660	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
XppCFBP412P_08685	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XppCFBP412P_08695	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
XppCFBP412P_08700	COG4988	ABC transporter
XppCFBP412P_08710	COG1294	oxidase, subunit
XppCFBP412P_08740	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
XppCFBP412P_08745	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
XppCFBP412P_08755	COG0165	Argininosuccinate lyase
XppCFBP412P_08760	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
XppCFBP412P_08770	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
XppCFBP412P_08775	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XppCFBP412P_08785	COG0137	argininosuccinate synthase activity
XppCFBP412P_08790	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
XppCFBP412P_08800	COG0215	cysteine-tRNA ligase activity
XppCFBP412P_08805	COG2166	iron-sulfur cluster assembly
XppCFBP412P_08820	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
XppCFBP412P_08825	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
XppCFBP412P_08855	COG4302	ethanolamine ammonia-lyase activity
XppCFBP412P_08885	COG3039	Transposase
XppCFBP412P_08915	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
XppCFBP412P_08920	COG0402	S-adenosylhomocysteine deaminase activity
XppCFBP412P_08930	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
XppCFBP412P_08935	COG1509	lysine 2,3-aminomutase activity
XppCFBP412P_08940	COG3300	MHYT domain
XppCFBP412P_08940	COG5001	Diguanylate cyclase
XppCFBP412P_08955	COG0483	inositol monophosphate 1-phosphatase activity
XppCFBP412P_08960	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
XppCFBP412P_08975	COG0488	(ABC) transporter
XppCFBP412P_08980	COG0513	Belongs to the DEAD box helicase family
XppCFBP412P_08985	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
XppCFBP412P_08990	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
XppCFBP412P_09010	COG0625	glutathione transferase activity
XppCFBP412P_09020	COG4681	YaeQ
XppCFBP412P_09025	COG2081	HI0933 family
XppCFBP412P_09035	COG0501	Belongs to the peptidase M48B family
XppCFBP412P_09040	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
XppCFBP412P_09045	COG1028	Short-chain dehydrogenase reductase Sdr
XppCFBP412P_09070	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
XppCFBP412P_09075	COG0860	N-Acetylmuramoyl-L-alanine amidase
XppCFBP412P_09080	COG0802	atpase or kinase
XppCFBP412P_09085	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
XppCFBP412P_09085	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
XppCFBP412P_09090	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
XppCFBP412P_09095	COG1570	exodeoxyribonuclease VII activity
XppCFBP412P_09110	COG1262	PFAM Formylglycine-generating sulfatase enzyme
XppCFBP412P_09155	COG0835	chemotaxis
XppCFBP412P_09160	COG0840	transmembrane signaling receptor activity
XppCFBP412P_09165	COG2094	Belongs to the DNA glycosylase MPG family
XppCFBP412P_09170	COG1201	RNA secondary structure unwinding
XppCFBP412P_09190	COG2969	positive regulation of protein catabolic process
XppCFBP412P_09195	COG0625	glutathione transferase activity
XppCFBP412P_09200	COG2857	Cytochrome c1
XppCFBP412P_09205	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
XppCFBP412P_09210	COG0723	plastoquinol--plastocyanin reductase activity
XppCFBP412P_09220	COG0741	lytic transglycosylase activity
XppCFBP412P_09235	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
XppCFBP412P_09240	COG1702	phosphate starvation-inducible protein PhoH
XppCFBP412P_09250	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
XppCFBP412P_09260	COG4535	Mg2 and Co2 transporter CorC
XppCFBP412P_09275	COG1012	belongs to the aldehyde dehydrogenase family
XppCFBP412P_09280	COG1177	transmembrane transport
XppCFBP412P_09285	COG1176	ABC-type spermidine putrescine transport system, permease component I
XppCFBP412P_09290	COG3842	ATPase activity
XppCFBP412P_09310	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
XppCFBP412P_09325	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
XppCFBP412P_09330	COG0174	glutamine synthetase
XppCFBP412P_09335	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XppCFBP412P_09345	COG2703	oxygen carrier activity
XppCFBP412P_09350	COG0477	Major facilitator Superfamily
XppCFBP412P_09360	COG0243	molybdopterin cofactor binding
XppCFBP412P_09365	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
XppCFBP412P_09370	COG2223	nitrite transmembrane transporter activity
XppCFBP412P_09385	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
XppCFBP412P_09395	COG2733	membrane
XppCFBP412P_09400	COG0784	Response regulator, receiver
XppCFBP412P_09400	COG2205	protein histidine kinase activity
XppCFBP412P_09400	COG5002	protein histidine kinase activity
XppCFBP412P_09410	COG0477	Major facilitator Superfamily
XppCFBP412P_09445	COG2902	Dehydrogenase
XppCFBP412P_09455	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XppCFBP412P_09460	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XppCFBP412P_09465	COG1609	Transcriptional regulator
XppCFBP412P_09470	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
XppCFBP412P_09470	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
XppCFBP412P_09475	COG1105	Belongs to the carbohydrate kinase PfkB family
XppCFBP412P_09480	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
XppCFBP412P_09480	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
XppCFBP412P_09500	COG3328	transposase activity
XppCFBP412P_09510	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
XppCFBP412P_09520	COG1862	Preprotein translocase
XppCFBP412P_09525	COG0343	queuine tRNA-ribosyltransferase activity
XppCFBP412P_09530	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
XppCFBP412P_09570	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
XppCFBP412P_09575	COG3291	Pkd domain containing protein
XppCFBP412P_09580	COG0405	Gamma-glutamyltransferase
XppCFBP412P_09585	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
XppCFBP412P_09600	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
XppCFBP412P_09605	COG0742	ribosomal rna small subunit methyltransferase
XppCFBP412P_09610	COG0326	Molecular chaperone. Has ATPase activity
XppCFBP412P_09690	COG3702	type iv secretory pathway
XppCFBP412P_09710	COG2948	multi-organism process
XppCFBP412P_09730	COG3505	Type IV secretory pathway VirD4
XppCFBP412P_09745	COG0556	nucleotide-excision repair
XppCFBP412P_09910	COG3179	chitinase
XppCFBP412P_09960	COG4695	Portal protein
XppCFBP412P_10030	COG3275	phosphorelay sensor kinase activity
XppCFBP412P_10035	COG1611	Belongs to the LOG family
XppCFBP412P_10050	COG2095	MarC family integral membrane protein
XppCFBP412P_10060	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
XppCFBP412P_10095	COG1185	polyribonucleotide nucleotidyltransferase activity
XppCFBP412P_10100	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
XppCFBP412P_10105	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
XppCFBP412P_10110	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
XppCFBP412P_10115	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
XppCFBP412P_10120	COG0195	Participates in both transcription termination and antitermination
XppCFBP412P_10125	COG0779	Required for maturation of 30S ribosomal subunits
XppCFBP412P_10135	COG1007	ATP synthesis coupled electron transport
XppCFBP412P_10160	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XppCFBP412P_10165	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
XppCFBP412P_10175	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
XppCFBP412P_10180	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
XppCFBP412P_10185	COG0649	NAD binding
XppCFBP412P_10190	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XppCFBP412P_10195	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XppCFBP412P_10200	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XppCFBP412P_10215	COG0149	triose-phosphate isomerase activity
XppCFBP412P_10220	COG4221	oxidoreductase activity
XppCFBP412P_10250	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
XppCFBP412P_10255	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
XppCFBP412P_10260	COG0159	tryptophan synthase activity
XppCFBP412P_10270	COG0133	tryptophan synthase activity
XppCFBP412P_10280	COG0135	phosphoribosylanthranilate isomerase activity
XppCFBP412P_10285	COG0101	tRNA pseudouridine synthase activity
XppCFBP412P_10300	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
XppCFBP412P_10305	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
XppCFBP412P_10310	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
XppCFBP412P_10315	COG2890	protein-(glutamine-N5) methyltransferase activity
XppCFBP412P_10325	COG0688	phosphatidylethanolamine metabolic process
XppCFBP412P_10335	COG0433	COG0433 Predicted ATPase
XppCFBP412P_10360	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XppCFBP412P_10365	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
XppCFBP412P_10385	COG0717	Belongs to the dCTP deaminase family
XppCFBP412P_10395	COG0489	protein tyrosine kinase activity
XppCFBP412P_10425	COG3590	peptidase
XppCFBP412P_10450	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XppCFBP412P_10455	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XppCFBP412P_10460	COG2311	Membrane
XppCFBP412P_10465	COG1047	Peptidyl-prolyl cis-trans
XppCFBP412P_10470	COG0791	NLP P60 protein
XppCFBP412P_10475	COG0791	NLP P60 protein
XppCFBP412P_10485	COG4106	trans-aconitate 2-methyltransferase activity
XppCFBP412P_10490	COG1301	dicarboxylic acid transport
XppCFBP412P_10495	COG1785	Belongs to the alkaline phosphatase family
XppCFBP412P_10505	COG0037	tRNA processing
XppCFBP412P_10510	COG1722	exodeoxyribonuclease VII activity
XppCFBP412P_10515	COG0142	geranyltranstransferase activity
XppCFBP412P_10520	COG4104	PAAR repeat-containing protein
XppCFBP412P_10530	COG0312	modulator of DNA gyrase
XppCFBP412P_10535	COG3028	Belongs to the UPF0307 family
XppCFBP412P_10540	COG0312	modulator of DNA gyrase
XppCFBP412P_10550	COG3164	Protein of unknown function
XppCFBP412P_10560	COG0424	maF-like protein
XppCFBP412P_10565	COG2968	Membrane
XppCFBP412P_10580	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
XppCFBP412P_10595	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
XppCFBP412P_10615	COG0495	leucyl-tRNA aminoacylation
XppCFBP412P_10625	COG3118	belongs to the thioredoxin family
XppCFBP412P_10650	COG2155	Conserved Protein
XppCFBP412P_10700	COG1132	(ABC) transporter
XppCFBP412P_10730	COG0745	RESPONSE REGULATOR receiver
XppCFBP412P_10735	COG5000	phosphorelay sensor kinase activity
XppCFBP412P_10735	COG5002	protein histidine kinase activity
XppCFBP412P_10740	COG0475	glutathione-regulated potassium exporter activity
XppCFBP412P_10750	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
XppCFBP412P_10770	COG1187	pseudouridine synthase activity
XppCFBP412P_10775	COG5001	Diguanylate cyclase
XppCFBP412P_10775	COG5002	protein histidine kinase activity
XppCFBP412P_10785	COG1595	DNA-templated transcription, initiation
XppCFBP412P_10900	COG0667	Aldo Keto reductase
XppCFBP412P_10905	COG2814	Major facilitator Superfamily
XppCFBP412P_10910	COG0583	DNA-binding transcription factor activity
XppCFBP412P_10920	COG2207	Transcriptional regulator
XppCFBP412P_10930	COG1309	transcriptional regulator
XppCFBP412P_10940	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XppCFBP412P_10955	COG0735	belongs to the Fur family
XppCFBP412P_10960	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
XppCFBP412P_10985	COG4452	Inner membrane protein CreD
XppCFBP412P_11005	COG0745	RESPONSE REGULATOR receiver
XppCFBP412P_11010	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
XppCFBP412P_11020	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
XppCFBP412P_11030	COG0643	Histidine kinase
XppCFBP412P_11030	COG2198	Histidine kinase
XppCFBP412P_11035	COG0840	transmembrane signaling receptor activity
XppCFBP412P_11040	COG0835	chemotaxis
XppCFBP412P_11045	COG2199	diguanylate cyclase activity
XppCFBP412P_11045	COG2200	EAL domain
XppCFBP412P_11045	COG2202	Pas domain
XppCFBP412P_11050	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
XppCFBP412P_11055	COG2201	protein-glutamate methylesterase activity
XppCFBP412P_11070	COG3590	peptidase
XppCFBP412P_11085	COG1515	deoxyribonuclease V activity
XppCFBP412P_11095	COG1741	Belongs to the pirin family
XppCFBP412P_11110	COG1741	Belongs to the pirin family
XppCFBP412P_11115	COG1966	Carbon starvation protein
XppCFBP412P_11120	COG2879	small protein
XppCFBP412P_11165	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
XppCFBP412P_11170	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XppCFBP412P_11175	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
XppCFBP412P_11180	COG2080	2 iron, 2 sulfur cluster binding
XppCFBP412P_11185	COG1028	Short-chain dehydrogenase reductase Sdr
XppCFBP412P_11185	COG3321	synthase
XppCFBP412P_11185	COG0604	alcohol dehydrogenase
XppCFBP412P_11190	COG3706	GGDEF domain
XppCFBP412P_11190	COG2203	Gaf domain
XppCFBP412P_11190	COG5001	Diguanylate cyclase
XppCFBP412P_11190	COG4251	negative regulation of phosphorylation
XppCFBP412P_11195	COG0629	single-stranded DNA binding
XppCFBP412P_11200	COG0142	geranyltranstransferase activity
XppCFBP412P_11210	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
XppCFBP412P_11225	COG0527	aspartate kinase activity
XppCFBP412P_11230	COG0384	phenazine biosynthesis protein PhzF
XppCFBP412P_11235	COG0384	phenazine biosynthesis protein PhzF
XppCFBP412P_11245	COG1764	response to oxidative stress
XppCFBP412P_11250	COG0540	Belongs to the ATCase OTCase family
XppCFBP412P_11255	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
XppCFBP412P_11260	COG1678	Uncharacterized ACR, COG1678
XppCFBP412P_11265	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
XppCFBP412P_11270	COG0519	Catalyzes the synthesis of GMP from XMP
XppCFBP412P_11295	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
XppCFBP412P_11310	COG0739	heme binding
XppCFBP412P_11330	COG0693	protein deglycase activity
XppCFBP412P_11340	COG1959	2 iron, 2 sulfur cluster binding
XppCFBP412P_11345	COG0719	Fe-S assembly protein
XppCFBP412P_11350	COG0396	ATPase activity
XppCFBP412P_11355	COG0719	Fe-S assembly protein
XppCFBP412P_11360	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
XppCFBP412P_11365	COG0456	acetyltransferase
XppCFBP412P_11370	COG2146	nitrite reductase [NAD(P)H] activity
XppCFBP412P_11375	COG4774	siderophore transport
XppCFBP412P_11380	COG3128	pkhd-type hydroxylase
XppCFBP412P_11405	COG3328	transposase activity
XppCFBP412P_11410	COG1477	protein flavinylation
XppCFBP412P_11415	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
XppCFBP412P_11425	COG1555	photosystem II stabilization
XppCFBP412P_11445	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
XppCFBP412P_11455	COG0628	permease
XppCFBP412P_11465	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
XppCFBP412P_11480	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
XppCFBP412P_11500	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
XppCFBP412P_11505	COG0271	Belongs to the BolA IbaG family
XppCFBP412P_11515	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
XppCFBP412P_11525	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
XppCFBP412P_11530	COG1137	ATPase activity
XppCFBP412P_11545	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
XppCFBP412P_11550	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
XppCFBP412P_11555	COG1660	Displays ATPase and GTPase activities
XppCFBP412P_11565	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
XppCFBP412P_11570	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
XppCFBP412P_11580	COG2239	Acts as a magnesium transporter
XppCFBP412P_11590	COG1294	oxidase, subunit
XppCFBP412P_11610	COG1113	amino acid transport
XppCFBP412P_11640	COG2197	response regulator
XppCFBP412P_11645	COG0531	amino acid
XppCFBP412P_11735	COG2814	Major facilitator Superfamily
XppCFBP412P_11745	COG0754	glutathionylspermidine amidase activity
XppCFBP412P_11770	COG1842	Phage shock protein A
XppCFBP412P_11780	COG0259	pyridoxamine-phosphate oxidase activity
XppCFBP412P_11785	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
XppCFBP412P_11790	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
XppCFBP412P_11800	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
XppCFBP412P_11805	COG2814	Major facilitator Superfamily
XppCFBP412P_11830	COG0784	Response regulator, receiver
XppCFBP412P_11830	COG2205	protein histidine kinase activity
XppCFBP412P_11830	COG2198	Histidine kinase
XppCFBP412P_11835	COG2353	YceI-like domain
XppCFBP412P_11855	COG1760	l-serine dehydratase
XppCFBP412P_11865	COG0460	homoserine dehydrogenase
XppCFBP412P_11865	COG0527	aspartate kinase activity
XppCFBP412P_11870	COG0626	cystathionine gamma-synthase activity
XppCFBP412P_11875	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XppCFBP412P_11880	COG0739	heme binding
XppCFBP412P_11885	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
XppCFBP412P_11890	COG1272	protein, Hemolysin III
XppCFBP412P_11895	COG2982	Protein involved in outer membrane biogenesis
XppCFBP412P_11900	COG0517	IMP dehydrogenase activity
XppCFBP412P_11900	COG0516	GMP reductase activity
XppCFBP412P_11905	COG0463	Glycosyl transferase, family 2
XppCFBP412P_11910	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
XppCFBP412P_11915	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
XppCFBP412P_11925	COG4771	TonB-dependent receptor
XppCFBP412P_11930	COG1309	transcriptional regulator
XppCFBP412P_11940	COG1960	acyl-CoA dehydrogenase activity
XppCFBP412P_11965	COG3328	transposase activity
XppCFBP412P_11990	COG0509	glycine decarboxylation via glycine cleavage system
XppCFBP412P_11995	COG0404	The glycine cleavage system catalyzes the degradation of glycine
XppCFBP412P_12005	COG0330	HflC and HflK could
XppCFBP412P_12010	COG1742	UPF0060 membrane protein
XppCFBP412P_12015	COG3956	TIGRFAM MazG family protein
XppCFBP412P_12025	COG0494	nUDIX hydrolase
XppCFBP412P_12035	COG1385	rRNA (uridine-N3-)-methyltransferase activity
XppCFBP412P_12040	COG0837	glucose binding
XppCFBP412P_12065	COG1388	LysM domain
XppCFBP412P_12065	COG3858	chitin binding
XppCFBP412P_12070	COG3525	Glycosyl hydrolase, family 20, catalytic domain
XppCFBP412P_12080	COG1472	Belongs to the glycosyl hydrolase 3 family
XppCFBP412P_12090	COG3537	Alpha-1,2-mannosidase
XppCFBP412P_12135	COG3142	Participates in the control of copper homeostasis
XppCFBP412P_12140	COG1446	asparaginase
XppCFBP412P_12170	COG2198	Histidine kinase
XppCFBP412P_12170	COG0643	Histidine kinase
XppCFBP412P_12170	COG0784	Response regulator, receiver
XppCFBP412P_12175	COG0840	transmembrane signaling receptor activity
XppCFBP412P_12180	COG0835	chemotaxis
XppCFBP412P_12195	COG0189	ligase activity
XppCFBP412P_12205	COG1397	ADP-ribosylglycohydrolase
XppCFBP412P_12215	COG1199	ATP-dependent helicase activity
XppCFBP412P_12225	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
XppCFBP412P_12230	COG1215	transferase activity, transferring glycosyl groups
XppCFBP412P_12245	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
XppCFBP412P_12255	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
XppCFBP412P_12260	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
XppCFBP412P_12265	COG0535	radical SAM domain protein
XppCFBP412P_12270	COG0535	radical SAM domain protein
XppCFBP412P_12285	COG0837	glucose binding
XppCFBP412P_12295	COG3328	transposase activity
XppCFBP412P_12305	COG1643	Atp-dependent helicase
XppCFBP412P_12310	COG0783	Belongs to the Dps family
XppCFBP412P_12315	COG0514	ATP-dependent DNA helicase (RecQ)
XppCFBP412P_12350	COG0840	transmembrane signaling receptor activity
XppCFBP412P_12370	COG3920	Histidine kinase
XppCFBP412P_12375	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
XppCFBP412P_12385	COG0602	queuosine metabolic process
XppCFBP412P_12395	COG2885	chlorophyll binding
XppCFBP412P_12400	COG0823	Involved in the tonB-independent uptake of proteins
XppCFBP412P_12410	COG0848	biopolymer transport protein
XppCFBP412P_12420	COG0824	Thioesterase
XppCFBP412P_12425	COG2255	four-way junction helicase activity
XppCFBP412P_12435	COG3158	transport of potassium into the cell
XppCFBP412P_12440	COG0632	four-way junction helicase activity
XppCFBP412P_12445	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
XppCFBP412P_12450	COG0217	transcriptional regulatory protein
XppCFBP412P_12465	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
XppCFBP412P_12480	COG0477	Major facilitator Superfamily
XppCFBP412P_12505	COG0657	acetylesterase activity
XppCFBP412P_12505	COG2755	lipolytic protein G-D-S-L family
XppCFBP412P_12525	COG0488	(ABC) transporter
XppCFBP412P_12560	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
XppCFBP412P_12560	COG4651	solute:proton antiporter activity
XppCFBP412P_12575	COG3328	transposase activity
XppCFBP412P_12590	COG4772	TonB-dependent receptor
XppCFBP412P_12600	COG4264	IucA IucC family
XppCFBP412P_12615	COG0019	diaminopimelate decarboxylase activity
XppCFBP412P_12640	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
XppCFBP412P_12650	COG1492	cobalamin metabolic process
XppCFBP412P_12660	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
XppCFBP412P_12685	COG4206	TonB-dependent receptor
XppCFBP412P_12695	COG0542	response to heat
XppCFBP412P_12745	COG1877	trehalose-phosphatase activity
XppCFBP412P_12750	COG3387	PFAM Glycoside hydrolase 15-related
XppCFBP412P_12775	COG0840	transmembrane signaling receptor activity
XppCFBP412P_12780	COG3011	Protein conserved in bacteria
XppCFBP412P_12795	COG0564	pseudouridine synthase activity
XppCFBP412P_12800	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XppCFBP412P_12810	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XppCFBP412P_12810	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
XppCFBP412P_12825	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
XppCFBP412P_12830	COG0045	succinate-CoA ligase (ADP-forming) activity
XppCFBP412P_12875	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
XppCFBP412P_12880	COG0237	dephospho-CoA kinase activity
XppCFBP412P_12920	COG0745	RESPONSE REGULATOR receiver
XppCFBP412P_12930	COG0189	ligase activity
XppCFBP412P_12975	COG2003	Belongs to the UPF0758 family
XppCFBP412P_12995	COG3328	transposase activity
XppCFBP412P_13030	COG2022	thiamine diphosphate biosynthetic process
XppCFBP412P_13040	COG0220	tRNA (guanine-N7-)-methyltransferase activity
XppCFBP412P_13045	COG0471	metal ion transport
XppCFBP412P_13045	COG3273	potassium ion transport
XppCFBP412P_13070	COG1970	mechanosensitive ion channel activity
XppCFBP412P_13080	COG1609	Transcriptional regulator
XppCFBP412P_13090	COG3250	beta-galactosidase activity
XppCFBP412P_13095	COG4948	Mandelate Racemase Muconate Lactonizing
XppCFBP412P_13105	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
XppCFBP412P_13115	COG0308	aminopeptidase N
XppCFBP412P_13120	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XppCFBP412P_13130	COG2895	sulfate adenylyltransferase (ATP) activity
XppCFBP412P_13130	COG0529	Catalyzes the synthesis of activated sulfate
XppCFBP412P_13135	COG0175	sulfate reduction
XppCFBP412P_13140	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
XppCFBP412P_13145	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
XppCFBP412P_13150	COG0175	sulfate reduction
XppCFBP412P_13170	COG2198	Histidine kinase
XppCFBP412P_13170	COG0784	Response regulator, receiver
XppCFBP412P_13170	COG2205	protein histidine kinase activity
XppCFBP412P_13190	COG1648	precorrin-2 dehydrogenase activity
XppCFBP412P_13190	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
XppCFBP412P_13205	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
XppCFBP412P_13210	COG3588	fructose-bisphosphate aldolase
XppCFBP412P_13220	COG0469	pyruvate kinase activity
XppCFBP412P_13230	COG0126	phosphoglycerate kinase activity
XppCFBP412P_13265	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
XppCFBP412P_13275	COG3047	cAMP biosynthetic process
XppCFBP412P_13290	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XppCFBP412P_13290	COG3453	Protein conserved in bacteria
XppCFBP412P_13295	COG0725	ABC transporter, periplasmic molybdate-binding protein
XppCFBP412P_13300	COG4149	molybdate abc transporter
XppCFBP412P_13305	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
XppCFBP412P_13325	COG0642	Histidine kinase
XppCFBP412P_13350	COG1022	Amp-dependent synthetase and ligase
XppCFBP412P_13375	COG1376	ErfK ybiS ycfS ynhG family protein
XppCFBP412P_13380	COG0739	heme binding
XppCFBP412P_13385	COG4773	Receptor
XppCFBP412P_13400	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
XppCFBP412P_13405	COG1301	dicarboxylic acid transport
XppCFBP412P_13415	COG2304	oxidoreductase activity
XppCFBP412P_13435	COG0714	Associated with various cellular activities
XppCFBP412P_13465	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
XppCFBP412P_13485	COG1957	nucleoside hydrolase
XppCFBP412P_13490	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
XppCFBP412P_13500	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
XppCFBP412P_13515	COG1561	YicC-like family, N-terminal region
XppCFBP412P_13520	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
XppCFBP412P_13530	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
XppCFBP412P_13535	COG0635	Involved in the biosynthesis of porphyrin-containing compound
XppCFBP412P_13550	COG0006	proline dipeptidase activity
XppCFBP412P_13560	COG0006	proline dipeptidase activity
XppCFBP412P_13565	COG3079	Belongs to the UPF0149 family
XppCFBP412P_13585	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
XppCFBP412P_13605	COG2912	Transglutaminase-like superfamily
XppCFBP412P_13615	COG1773	rubredoxin
XppCFBP412P_13620	COG0352	thiamine-phosphate diphosphorylase activity
XppCFBP412P_13650	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
XppCFBP412P_13660	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
XppCFBP412P_13665	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XppCFBP412P_13695	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
XppCFBP412P_13700	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XppCFBP412P_13705	COG1028	Short-chain dehydrogenase reductase Sdr
XppCFBP412P_13715	COG0671	phosphoesterase, PA-phosphatase related
XppCFBP412P_13725	COG3781	membrane
XppCFBP412P_13735	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
XppCFBP412P_13740	COG0563	adenylate kinase activity
XppCFBP412P_13755	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
XppCFBP412P_13765	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
XppCFBP412P_13785	COG3710	Transcriptional regulator
XppCFBP412P_13790	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
XppCFBP412P_13805	COG0840	transmembrane signaling receptor activity
XppCFBP412P_13810	COG0405	Gamma-glutamyltransferase
XppCFBP412P_13815	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
XppCFBP412P_13835	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
XppCFBP412P_13840	COG0473	3-isopropylmalate dehydrogenase activity
XppCFBP412P_13845	COG0066	3-isopropylmalate dehydratase activity
XppCFBP412P_13850	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
XppCFBP412P_13870	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
XppCFBP412P_13875	COG1538	Outer membrane efflux protein
XppCFBP412P_13880	COG1519	Transferase
XppCFBP412P_13885	COG1560	Kdo2-lipid A biosynthetic process
XppCFBP412P_13910	COG0280	phosphate acetyltransferase
XppCFBP412P_13910	COG0281	malic enzyme
XppCFBP412P_13915	COG1301	dicarboxylic acid transport
XppCFBP412P_13940	COG0583	DNA-binding transcription factor activity
XppCFBP412P_13945	COG0667	Aldo Keto reductase
XppCFBP412P_13960	COG2197	response regulator
XppCFBP412P_13975	COG0642	Histidine kinase
XppCFBP412P_13995	COG2851	Citrate transporter
XppCFBP412P_14000	COG1028	Short-chain dehydrogenase reductase Sdr
XppCFBP412P_14005	COG1609	Transcriptional regulator
XppCFBP412P_14010	COG2211	Major facilitator Superfamily
XppCFBP412P_14035	COG1162	GTPase activity
XppCFBP412P_14040	COG0436	Aminotransferase
XppCFBP412P_14055	COG0726	polysaccharide deacetylase
XppCFBP412P_14060	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
XppCFBP412P_14075	COG3964	amidohydrolase
XppCFBP412P_14080	COG0402	S-adenosylhomocysteine deaminase activity
XppCFBP412P_14115	COG3328	transposase activity
XppCFBP412P_14125	COG1307	EDD domain protein, DegV family
XppCFBP412P_14145	COG3791	Glutathione-dependent formaldehyde-activating
XppCFBP412P_14175	COG2205	protein histidine kinase activity
XppCFBP412P_14190	COG0218	Necessary for normal cell division and for the maintenance of normal septation
XppCFBP412P_14205	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
XppCFBP412P_14215	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
XppCFBP412P_14220	COG1012	belongs to the aldehyde dehydrogenase family
XppCFBP412P_14225	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
XppCFBP412P_14245	COG1183	phosphatidylcholine synthase activity
XppCFBP412P_14255	COG0442	prolyl-tRNA aminoacylation
XppCFBP412P_14270	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
XppCFBP412P_14275	COG1127	ABC transporter
XppCFBP412P_14280	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
XppCFBP412P_14280	COG3218	ABC-type transport auxiliary lipoprotein component
XppCFBP412P_14310	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
XppCFBP412P_14315	COG0662	Cupin 2, conserved barrel domain protein
XppCFBP412P_14315	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
XppCFBP412P_14345	COG2086	electron transfer activity
XppCFBP412P_14360	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
XppCFBP412P_14360	COG0546	phosphoglycolate phosphatase activity
XppCFBP412P_14365	COG0277	FAD linked oxidase domain protein
XppCFBP412P_14375	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XppCFBP412P_14395	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XppCFBP412P_14400	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
XppCFBP412P_14405	COG0438	transferase activity, transferring glycosyl groups
XppCFBP412P_14425	COG0438	transferase activity, transferring glycosyl groups
XppCFBP412P_14435	COG0626	cystathionine gamma-synthase activity
XppCFBP412P_14465	COG0625	glutathione transferase activity
XppCFBP412P_14480	COG0513	Belongs to the DEAD box helicase family
XppCFBP412P_14485	COG0720	synthase
XppCFBP412P_14495	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
XppCFBP412P_14505	COG1956	GAF domain-containing protein
XppCFBP412P_14520	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
XppCFBP412P_14525	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
XppCFBP412P_14535	COG4991	sh3 domain protein
XppCFBP412P_14545	COG0339	signal peptide processing
XppCFBP412P_14560	COG2132	Multicopper oxidase
XppCFBP412P_14595	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
XppCFBP412P_14600	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XppCFBP412P_14605	COG1136	(ABC) transporter
XppCFBP412P_14610	COG0577	efflux transmembrane transporter activity
XppCFBP412P_14610	COG1136	(ABC) transporter
XppCFBP412P_14630	COG4191	Histidine kinase
XppCFBP412P_14635	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
XppCFBP412P_14650	COG0355	proton-transporting ATP synthase activity, rotational mechanism
XppCFBP412P_14655	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
XppCFBP412P_14660	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
XppCFBP412P_14665	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
XppCFBP412P_14670	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
XppCFBP412P_14685	COG0356	it plays a direct role in the translocation of protons across the membrane
XppCFBP412P_14705	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XppCFBP412P_14715	COG0508	dehydrogenase complex catalyzes the overall conversion of
XppCFBP412P_14755	COG2011	ABC-type metal ion transport system permease component
XppCFBP412P_14760	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
XppCFBP412P_14765	COG0697	spore germination
XppCFBP412P_14770	COG1666	GTP binding
XppCFBP412P_14780	COG0784	Response regulator, receiver
XppCFBP412P_14780	COG2198	Histidine kinase
XppCFBP412P_14780	COG5002	protein histidine kinase activity
XppCFBP412P_14805	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
XppCFBP412P_14810	COG1187	pseudouridine synthase activity
XppCFBP412P_14815	COG2813	Specifically methylates the guanine in position
XppCFBP412P_14830	COG3039	Transposase
XppCFBP412P_14860	COG2205	protein histidine kinase activity
XppCFBP412P_14860	COG2202	Pas domain
XppCFBP412P_14880	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
XppCFBP412P_14885	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XppCFBP412P_14940	COG0842	Transport permease protein
XppCFBP412P_14945	COG1131	(ABC) transporter
XppCFBP412P_14950	COG0025	NhaP-type Na H and K H
XppCFBP412P_14960	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
XppCFBP412P_14965	COG1573	uracil-dna glycosylase
XppCFBP412P_14975	COG3384	dioxygenase
XppCFBP412P_14985	COG0583	DNA-binding transcription factor activity
XppCFBP412P_14995	COG0667	Aldo Keto reductase
XppCFBP412P_15010	COG3590	peptidase
XppCFBP412P_15025	COG0531	amino acid
XppCFBP412P_15040	COG2972	Histidine kinase
XppCFBP412P_15060	COG3685	Protein conserved in bacteria
XppCFBP412P_15065	COG3546	catalase activity
XppCFBP412P_15115	COG1271	oxidase subunit
XppCFBP412P_15120	COG1294	oxidase, subunit
XppCFBP412P_15135	COG1028	Short-chain dehydrogenase reductase Sdr
XppCFBP412P_15155	COG1063	alcohol dehydrogenase
XppCFBP412P_15165	COG3328	transposase activity
XppCFBP412P_15235	COG0251	oxidation-reduction process
XppCFBP412P_15260	COG0659	secondary active sulfate transmembrane transporter activity
XppCFBP412P_15265	COG0038	chloride channel
XppCFBP412P_15275	COG0024	Methionine aminopeptidase
XppCFBP412P_15310	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
XppCFBP412P_15315	COG1490	D-aminoacyl-tRNA deacylase activity
XppCFBP412P_15320	COG1560	Kdo2-lipid A biosynthetic process
XppCFBP412P_15365	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
XppCFBP412P_15365	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
XppCFBP412P_15370	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
XppCFBP412P_15375	COG0242	peptide deformylase activity
XppCFBP412P_15380	COG1652	LysM domain
XppCFBP412P_15385	COG0758	DNA mediated transformation
XppCFBP412P_15405	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
XppCFBP412P_15405	COG1754	DNA topoisomerase type I activity
XppCFBP412P_15410	COG0009	L-threonylcarbamoyladenylate synthase
XppCFBP412P_15425	COG1028	Short-chain dehydrogenase reductase Sdr
XppCFBP412P_15440	COG0616	signal peptide processing
XppCFBP412P_15445	COG0534	Mate efflux family protein
XppCFBP412P_15465	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
XppCFBP412P_15470	COG0625	glutathione transferase activity
XppCFBP412P_15485	COG1252	NADH dehydrogenase
XppCFBP412P_15490	COG2860	membrane
XppCFBP412P_15495	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
XppCFBP412P_15500	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
XppCFBP412P_15505	COG2201	protein-glutamate methylesterase activity
XppCFBP412P_15510	COG2177	Part of the ABC transporter FtsEX involved in
XppCFBP412P_15515	COG2884	Cell division ATP-binding protein ftsE
XppCFBP412P_15520	COG0513	Belongs to the DEAD box helicase family
XppCFBP412P_15525	COG3118	belongs to the thioredoxin family
XppCFBP412P_15530	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
XppCFBP412P_15540	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
XppCFBP412P_15565	COG1652	LysM domain
XppCFBP412P_15570	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
XppCFBP412P_15570	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
XppCFBP412P_15575	COG1473	amidohydrolase
XppCFBP412P_15580	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XppCFBP412P_15585	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XppCFBP412P_15605	COG5383	Protein conserved in bacteria
XppCFBP412P_15645	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
XppCFBP412P_15650	COG3023	N-Acetylmuramoyl-L-alanine amidase
XppCFBP412P_15670	COG0531	amino acid
XppCFBP412P_15690	COG3328	transposase activity
XppCFBP412P_15700	COG2133	pyrroloquinoline quinone binding
XppCFBP412P_15710	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
XppCFBP412P_15715	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
XppCFBP412P_15725	COG1610	YqeY-like protein
XppCFBP412P_15735	COG1295	ribonuclease BN
XppCFBP412P_15740	COG0358	DNA primase activity
XppCFBP412P_15755	COG0109	protoheme IX farnesyltransferase activity
XppCFBP412P_15785	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
XppCFBP412P_15795	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
XppCFBP412P_15835	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
XppCFBP412P_15840	COG0739	heme binding
XppCFBP412P_15845	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
XppCFBP412P_15855	COG2223	nitrite transmembrane transporter activity
XppCFBP412P_15860	COG0708	Exodeoxyribonuclease III
XppCFBP412P_15865	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
XppCFBP412P_15875	COG1192	Involved in chromosome partitioning
XppCFBP412P_15880	COG1475	DNA binding
XppCFBP412P_15895	COG0463	Glycosyl transferase, family 2
XppCFBP412P_15915	COG0756	dUTP diphosphatase activity
XppCFBP412P_15920	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
XppCFBP412P_15925	COG2003	Belongs to the UPF0758 family
XppCFBP412P_15930	COG0018	arginyl-trna synthetase
XppCFBP412P_15945	COG4221	oxidoreductase activity
XppCFBP412P_15950	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
XppCFBP412P_15950	COG2755	lipolytic protein G-D-S-L family
XppCFBP412P_15960	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
XppCFBP412P_15965	COG1166	arginine decarboxylase activity
XppCFBP412P_15970	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
XppCFBP412P_15990	COG3525	Glycosyl hydrolase, family 20, catalytic domain
XppCFBP412P_15990	COG3291	Pkd domain containing protein
XppCFBP412P_16010	COG0606	chelatase, subunit chli
XppCFBP412P_16020	COG4943	cyclic-guanylate-specific phosphodiesterase activity
XppCFBP412P_16050	COG1690	Belongs to the RtcB family
XppCFBP412P_16090	COG1090	epimerase
XppCFBP412P_16100	COG0642	Histidine kinase
XppCFBP412P_16120	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XppCFBP412P_16145	COG1011	Hydrolase
XppCFBP412P_16150	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
XppCFBP412P_16165	COG0753	catalase activity
XppCFBP412P_16185	COG2197	response regulator
XppCFBP412P_16190	COG4585	Histidine kinase
XppCFBP412P_16195	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XppCFBP412P_16200	COG1136	(ABC) transporter
XppCFBP412P_16225	COG0697	spore germination
XppCFBP412P_16250	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XppCFBP412P_16255	COG0180	Tryptophanyl-tRNA synthetase
XppCFBP412P_16260	COG3237	CsbD-like
XppCFBP412P_16305	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
XppCFBP412P_16320	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
XppCFBP412P_16325	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
XppCFBP412P_16325	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
XppCFBP412P_16340	COG3228	Belongs to the MtfA family
XppCFBP412P_16370	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
XppCFBP412P_16410	COG3328	transposase activity
XppCFBP412P_16425	COG1199	ATP-dependent helicase activity
XppCFBP412P_16440	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
XppCFBP412P_16530	COG4555	ABC transporter
XppCFBP412P_16540	COG1476	TRANSCRIPTIONal
XppCFBP412P_16560	COG1230	cation diffusion facilitator family transporter
XppCFBP412P_16565	COG0543	2 iron, 2 sulfur cluster binding
XppCFBP412P_16565	COG0633	Ferredoxin
XppCFBP412P_16570	COG1131	(ABC) transporter
XppCFBP412P_16575	COG0842	Transport permease protein
XppCFBP412P_16580	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
XppCFBP412P_16605	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XppCFBP412P_16625	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
XppCFBP412P_16630	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
XppCFBP412P_16645	COG0045	succinate-CoA ligase (ADP-forming) activity
XppCFBP412P_16645	COG1042	CoA-binding domain protein
XppCFBP412P_16645	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
XppCFBP412P_16650	COG2239	Acts as a magnesium transporter
XppCFBP412P_16680	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
XppCFBP412P_16685	COG3387	PFAM Glycoside hydrolase 15-related
XppCFBP412P_16700	COG3100	YcgL domain-containing protein
XppCFBP412P_16705	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
XppCFBP412P_16715	COG0463	Glycosyl transferase, family 2
XppCFBP412P_16725	COG1028	Short-chain dehydrogenase reductase Sdr
XppCFBP412P_16765	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
XppCFBP412P_16780	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
XppCFBP412P_16830	COG0408	coproporphyrinogen oxidase activity
XppCFBP412P_16865	COG0515	serine threonine protein kinase
XppCFBP412P_16870	COG0631	protein serine/threonine phosphatase activity
XppCFBP412P_16895	COG0667	Aldo Keto reductase
XppCFBP412P_16900	COG0583	DNA-binding transcription factor activity
XppCFBP412P_16975	COG0154	amidase activity
XppCFBP412P_16980	COG3039	Transposase
XppCFBP412P_17005	COG3328	transposase activity
XppCFBP412P_17090	COG0210	DNA helicase
XppCFBP412P_17105	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XppCFBP412P_17110	COG0583	DNA-binding transcription factor activity
XppCFBP412P_17115	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
XppCFBP412P_17130	COG2159	amidohydrolase
XppCFBP412P_17155	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XppCFBP412P_17180	COG0357	Ribosomal RNA small subunit methyltransferase G
XppCFBP412P_17185	COG3540	Alkaline phosphatase
XppCFBP412P_17195	COG2091	lysine biosynthetic process via aminoadipic acid
XppCFBP412P_17210	COG0708	Exodeoxyribonuclease III
XppCFBP412P_17215	COG1846	Transcriptional regulator
XppCFBP412P_17215	COG1940	carbohydrate kinase activity
XppCFBP412P_17225	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
XppCFBP412P_17235	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
XppCFBP412P_17240	COG3162	membrane
XppCFBP412P_17250	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
XppCFBP412P_17280	COG3507	Belongs to the glycosyl hydrolase 43 family
XppCFBP412P_17300	COG1028	Short-chain dehydrogenase reductase Sdr
XppCFBP412P_17305	COG0179	Fumarylacetoacetate (FAA) hydrolase
XppCFBP412P_17310	COG4948	Mandelate Racemase Muconate Lactonizing
XppCFBP412P_17315	COG3254	rhamnose metabolic process
XppCFBP412P_17320	COG0738	Major facilitator superfamily
XppCFBP412P_17325	COG1414	Transcriptional regulator
XppCFBP412P_17330	COG1917	Cupin 2, conserved barrel domain protein
XppCFBP412P_17330	COG2207	Transcriptional regulator
XppCFBP412P_17340	COG1971	Probably functions as a manganese efflux pump
XppCFBP412P_17345	COG2205	protein histidine kinase activity
XppCFBP412P_17360	COG3459	Glycosyltransferase 36 associated
XppCFBP412P_17365	COG2211	Major facilitator Superfamily
XppCFBP412P_17370	COG3265	gluconokinase activity
XppCFBP412P_17380	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XppCFBP412P_17400	COG2911	Protein conserved in bacteria
XppCFBP412P_17405	COG0729	surface antigen
XppCFBP412P_17410	COG4771	TonB-dependent receptor
XppCFBP412P_17420	COG0457	Tetratricopeptide repeat
XppCFBP412P_17430	COG0752	glycyl-tRNA synthetase alpha subunit
XppCFBP412P_17435	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
XppCFBP412P_17455	COG0518	GMP synthase (glutamine-hydrolyzing) activity
XppCFBP412P_17455	COG0519	Catalyzes the synthesis of GMP from XMP
XppCFBP412P_17470	COG0805	protein transport
XppCFBP412P_17475	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
XppCFBP412P_17480	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
XppCFBP412P_17490	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
XppCFBP412P_17510	COG2974	May be involved in recombination
XppCFBP412P_17515	COG0037	tRNA processing
XppCFBP412P_17525	COG2115	Belongs to the xylose isomerase family
XppCFBP412P_17535	COG3661	Belongs to the glycosyl hydrolase 67 family
XppCFBP412P_17545	COG4948	Mandelate Racemase Muconate Lactonizing
XppCFBP412P_17555	COG1472	Belongs to the glycosyl hydrolase 3 family
XppCFBP412P_17560	COG0246	Mannitol dehydrogenase
XppCFBP412P_17625	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
XppCFBP412P_17650	COG3386	PFAM SMP-30 Gluconolaconase
XppCFBP412P_17660	COG3250	beta-galactosidase activity
XppCFBP412P_17665	COG1904	glucuronate isomerase
XppCFBP412P_17670	COG3693	PFAM glycoside hydrolase, family 10
XppCFBP412P_17680	COG3693	PFAM glycoside hydrolase, family 10
XppCFBP412P_17695	COG2211	Major facilitator Superfamily
XppCFBP412P_17745	COG3328	transposase activity
XppCFBP412P_17785	COG2937	Belongs to the GPAT DAPAT family
XppCFBP412P_17820	COG0284	orotidine-5'-phosphate decarboxylase activity
XppCFBP412P_17825	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
XppCFBP412P_17840	COG0635	Involved in the biosynthesis of porphyrin-containing compound
XppCFBP412P_17890	COG0210	DNA helicase
XppCFBP412P_17895	COG1435	thymidine kinase activity
XppCFBP412P_17905	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
XppCFBP412P_17915	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
XppCFBP412P_17945	COG3135	benzoate transporter
XppCFBP412P_17975	COG0676	glucose-6-phosphate 1-epimerase activity
XppCFBP412P_17985	COG3012	SEC-C Motif Domain Protein
XppCFBP412P_18035	COG3039	Transposase
XppCFBP412P_18080	COG0730	response to heat
XppCFBP412P_18090	COG3328	transposase activity
XppCFBP412P_18105	COG0302	gtp cyclohydrolase
XppCFBP412P_18120	COG1566	PFAM secretion protein HlyD family protein
XppCFBP412P_18130	COG1289	transmembrane transporter activity
XppCFBP412P_18135	COG0477	Major facilitator Superfamily
XppCFBP412P_18145	COG0583	DNA-binding transcription factor activity
XppCFBP412P_18150	COG4221	oxidoreductase activity
XppCFBP412P_18160	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XppCFBP412P_18185	COG3328	transposase activity
XppCFBP412P_18210	COG0564	pseudouridine synthase activity
XppCFBP412P_18240	COG3012	SEC-C Motif Domain Protein
XppCFBP412P_18310	COG4790	Type iii secretion
XppCFBP412P_18380	COG3039	Transposase
XppCFBP412P_18465	COG3039	Transposase
XppCFBP412P_18560	COG0439	Biotin carboxylase
XppCFBP412P_18590	COG1028	Short-chain dehydrogenase reductase Sdr
XppCFBP412P_18650	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
XppCFBP412P_18655	COG1074	ATP-dependent DNA helicase activity
XppCFBP412P_18660	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
XppCFBP412P_18695	COG1127	ABC transporter
XppCFBP412P_18700	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
XppCFBP412P_18705	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
XppCFBP412P_18720	COG2853	Lipoprotein
XppCFBP412P_18735	COG0386	Belongs to the glutathione peroxidase family
XppCFBP412P_18745	COG1322	Protein conserved in bacteria
XppCFBP412P_18755	COG0583	DNA-binding transcription factor activity
XppCFBP412P_18775	COG0531	amino acid
XppCFBP412P_18780	COG3537	Alpha-1,2-mannosidase
XppCFBP412P_18795	COG2199	diguanylate cyclase activity
XppCFBP412P_18795	COG2203	Gaf domain
XppCFBP412P_18800	COG3835	regulator
XppCFBP412P_18805	COG1929	Belongs to the glycerate kinase type-1 family
XppCFBP412P_18825	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
XppCFBP412P_18835	COG0861	Integral membrane protein TerC family
XppCFBP412P_18860	COG0584	glycerophosphoryl diester phosphodiesterase
XppCFBP412P_18875	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
XppCFBP412P_18880	COG0726	polysaccharide deacetylase
XppCFBP412P_18890	COG0706	membrane insertase activity
XppCFBP412P_18895	COG0594	ribonuclease P activity
XppCFBP412P_18920	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
XppCFBP412P_18925	COG0187	DNA topoisomerase II activity
XppCFBP412P_18935	COG0501	Belongs to the peptidase M48B family
XppCFBP412P_18980	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
XppCFBP412P_18990	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XppCFBP412P_19035	COG0793	Belongs to the peptidase S41A family
XppCFBP412P_19040	COG4942	peptidase
XppCFBP412P_19050	COG2234	aminopeptidase activity
XppCFBP412P_19060	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XppCFBP412P_19075	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XppCFBP412P_19085	COG1064	alcohol dehydrogenase
XppCFBP412P_19100	COG0493	'glutamate synthase
XppCFBP412P_19105	COG0067	glutamate synthase
XppCFBP412P_19105	COG0069	glutamate synthase activity
XppCFBP412P_19105	COG0070	glutamate synthase
XppCFBP412P_19200	COG1205	dead DEAH box helicase
XppCFBP412P_19200	COG1111	helicase
XppCFBP412P_19205	COG1272	protein, Hemolysin III
XppCFBP412P_19225	COG0300	oxidoreductase activity
XppCFBP412P_19230	COG1028	Short-chain dehydrogenase reductase Sdr
XppCFBP412P_19260	COG2249	NAD(P)H dehydrogenase (quinone) activity
XppCFBP412P_19275	COG3039	Transposase
XppCFBP412P_19290	COG3039	Transposase
XppCFBP412P_19295	COG3237	CsbD-like
XppCFBP412P_19340	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XppCFBP412P_19390	COG0714	Associated with various cellular activities
XppCFBP412P_19435	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
XppCFBP412P_19445	COG4772	TonB-dependent receptor
XppCFBP412P_19475	COG1304	FMN binding
XppCFBP412P_19480	COG1755	Isoprenylcysteine carboxyl methyltransferase
XppCFBP412P_19485	COG4585	Histidine kinase
XppCFBP412P_19490	COG2197	response regulator
XppCFBP412P_19520	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
XppCFBP412P_19575	COG3328	transposase activity
XppCFBP412P_19595	COG3039	Transposase
XppCFBP412P_19610	COG0366	Alpha amylase catalytic
XppCFBP412P_19615	COG0366	Alpha amylase catalytic
XppCFBP412P_19620	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
XppCFBP412P_19640	COG2755	lipolytic protein G-D-S-L family
XppCFBP412P_19640	COG0657	acetylesterase activity
XppCFBP412P_19650	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
XppCFBP412P_19665	COG3507	Belongs to the glycosyl hydrolase 43 family
XppCFBP412P_19670	COG1609	Transcriptional regulator
XppCFBP412P_19680	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
XppCFBP412P_19685	COG1028	Short-chain dehydrogenase reductase Sdr
XppCFBP412P_19695	COG2755	lipolytic protein G-D-S-L family
XppCFBP412P_19705	COG3186	Phenylalanine-4-hydroxylase
XppCFBP412P_19710	COG1522	sequence-specific DNA binding
XppCFBP412P_19720	COG1752	Esterase of the alpha-beta hydrolase superfamily
XppCFBP412P_19730	COG1119	ATPase activity
XppCFBP412P_19745	COG1125	glycine betaine transport
XppCFBP412P_19745	COG0517	IMP dehydrogenase activity
XppCFBP412P_19760	COG1262	PFAM Formylglycine-generating sulfatase enzyme
XppCFBP412P_19790	COG0489	protein tyrosine kinase activity
XppCFBP412P_19795	COG2062	phosphohistidine phosphatase, SixA
XppCFBP412P_19805	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XppCFBP412P_19850	COG1968	undecaprenyl-diphosphatase activity
XppCFBP412P_19860	COG0174	glutamine synthetase
XppCFBP412P_19865	COG0347	Belongs to the P(II) protein family
XppCFBP412P_19870	COG0004	ammonium transporteR
XppCFBP412P_19875	COG3852	Histidine kinase
XppCFBP412P_19880	COG2204	response regulator
XppCFBP412P_19885	COG2032	superoxide dismutase activity
XppCFBP412P_19890	COG2032	superoxide dismutase activity
XppCFBP412P_19905	COG0183	Belongs to the thiolase family
XppCFBP412P_19940	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
XppCFBP412P_19945	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
XppCFBP412P_19950	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
XppCFBP412P_19975	COG2205	protein histidine kinase activity
XppCFBP412P_20000	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
XppCFBP412P_20015	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XppCFBP412P_20020	COG3177	Filamentation induced by cAMP protein fic
XppCFBP412P_20025	COG0596	Alpha beta hydrolase
XppCFBP412P_20030	COG0727	PFAM Uncharacterised protein family (UPF0153)
XppCFBP412P_20035	COG0318	PFAM AMP-dependent synthetase and ligase
XppCFBP412P_20040	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XppCFBP412P_20055	COG1181	Belongs to the D-alanine--D-alanine ligase family
XppCFBP412P_20070	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
XppCFBP412P_20080	COG0564	pseudouridine synthase activity
XppCFBP412P_20100	COG1446	asparaginase
XppCFBP412P_20105	COG0339	signal peptide processing
XppCFBP412P_20140	COG0475	glutathione-regulated potassium exporter activity
XppCFBP412P_20145	COG0583	DNA-binding transcription factor activity
XppCFBP412P_20150	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
XppCFBP412P_20155	COG2224	Isocitrate lyase
XppCFBP412P_20175	COG3039	Transposase
XppCFBP412P_20195	COG4770	biotin carboxylase activity
XppCFBP412P_20200	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
XppCFBP412P_20205	COG1960	acyl-CoA dehydrogenase activity
XppCFBP412P_20275	COG0697	spore germination
XppCFBP412P_20285	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
XppCFBP412P_20290	COG1846	Transcriptional regulator
XppCFBP412P_20295	COG1764	response to oxidative stress
XppCFBP412P_20315	COG2130	NADP-dependent
XppCFBP412P_20330	COG1187	pseudouridine synthase activity
XppCFBP412P_20340	COG1643	Atp-dependent helicase
XppCFBP412P_20355	COG4807	Protein conserved in bacteria
XppCFBP412P_20365	COG2072	flavoprotein involved in K transport
XppCFBP412P_20385	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
XppCFBP412P_20395	COG0583	DNA-binding transcription factor activity
XppCFBP412P_20435	COG2252	PERMEase
XppCFBP412P_20460	COG0084	hydrolase, TatD family'
XppCFBP412P_20475	COG0583	DNA-binding transcription factor activity
XppCFBP412P_20480	COG2814	Major facilitator Superfamily
XppCFBP412P_20495	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
XppCFBP412P_20500	COG1902	pentaerythritol trinitrate reductase activity
XppCFBP412P_20520	COG0745	RESPONSE REGULATOR receiver
XppCFBP412P_20525	COG2205	protein histidine kinase activity
XppCFBP412P_20530	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XppCFBP412P_20555	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
XppCFBP412P_20560	COG0583	DNA-binding transcription factor activity
XppCFBP412P_20600	COG0702	epimerase
XppCFBP412P_20605	COG1733	regulation of RNA biosynthetic process
XppCFBP412P_20650	COG0129	dihydroxy-acid dehydratase activity
XppCFBP412P_20665	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
XppCFBP412P_20720	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
XppCFBP412P_20725	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
XppCFBP412P_20750	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
XppCFBP412P_20765	COG3485	protocatechuate 3,4-dioxygenase
XppCFBP412P_20770	COG3485	protocatechuate 3,4-dioxygenase
XppCFBP412P_20780	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XppCFBP412P_20785	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
XppCFBP412P_20795	COG1414	Transcriptional regulator
XppCFBP412P_20805	COG0657	acetylesterase activity
XppCFBP412P_20815	COG0445	tRNA wobble uridine modification
XppCFBP412P_20825	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
XppCFBP412P_20860	COG2267	carboxylic ester hydrolase activity
XppCFBP412P_20870	COG0156	8-amino-7-oxononanoate synthase activity
XppCFBP412P_20875	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
XppCFBP412P_20880	COG1040	competence protein
XppCFBP412P_20885	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
XppCFBP412P_20910	COG3039	Transposase
XppCFBP412P_20975	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
XppCFBP412P_21050	COG3264	Mechanosensitive ion channel
XppCFBP412P_21050	COG1511	domain protein
XppCFBP412P_21055	COG1368	sulfuric ester hydrolase activity
XppCFBP412P_21060	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
XppCFBP412P_21065	COG2354	Protein conserved in bacteria
XppCFBP412P_21075	COG0297	glycogen (starch) synthase activity
XppCFBP412P_21080	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
XppCFBP412P_21085	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
XppCFBP412P_21110	COG0702	epimerase
XppCFBP412P_21130	COG3328	transposase activity
XppCFBP412P_21140	COG3039	Transposase
XppCFBP412P_21145	COG1028	Short-chain dehydrogenase reductase Sdr
XppCFBP412P_21180	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XppCFBP412P_21185	COG1028	Short-chain dehydrogenase reductase Sdr
XppCFBP412P_21195	COG0513	Belongs to the DEAD box helicase family
XppCFBP412P_21200	COG0508	dehydrogenase complex catalyzes the overall conversion of
XppCFBP412P_21215	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
XppCFBP412P_21225	COG3483	tryptophan 2,3-dioxygenase activity
XppCFBP412P_21230	COG3104	oligopeptide transport
XppCFBP412P_21250	COG2852	Protein conserved in bacteria
XppCFBP412P_21255	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
XppCFBP412P_21275	COG1320	monovalent cation:proton antiporter activity
XppCFBP412P_21280	COG2212	antiporter activity
XppCFBP412P_21290	COG0651	ATP synthesis coupled electron transport
XppCFBP412P_21295	COG1006	Multisubunit Na H antiporter MnhC subunit
XppCFBP412P_21300	COG2111	Na H antiporter
XppCFBP412P_21300	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
XppCFBP412P_21340	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
XppCFBP412P_21345	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
XppCFBP412P_21365	COG1597	lipid kinase activity
XppCFBP412P_21390	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
XppCFBP412P_21395	COG0134	indole-3-glycerol-phosphate synthase activity
XppCFBP412P_21405	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XppCFBP412P_21410	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
XppCFBP412P_21420	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
XppCFBP412P_21430	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
XppCFBP412P_21445	COG1051	belongs to the nudix hydrolase family
XppCFBP412P_21485	COG0316	Belongs to the HesB IscA family
XppCFBP412P_21505	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
XppCFBP412P_21520	COG2814	Major facilitator Superfamily
XppCFBP412P_21530	COG2814	Major facilitator Superfamily
XppCFBP412P_21535	COG1289	transmembrane transporter activity
XppCFBP412P_21545	COG0151	Belongs to the GarS family
XppCFBP412P_21555	COG0138	bifunctional purine biosynthesis protein purh
XppCFBP412P_21560	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
XppCFBP412P_21565	COG2267	carboxylic ester hydrolase activity
XppCFBP412P_21570	COG0671	phosphoesterase, PA-phosphatase related
XppCFBP412P_21570	COG2453	phosphatase
XppCFBP412P_21595	COG4589	Belongs to the CDS family
XppCFBP412P_21600	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
XppCFBP412P_21625	COG2264	protein methyltransferase activity
XppCFBP412P_21645	COG0439	Biotin carboxylase
XppCFBP412P_21655	COG0511	ligase activity, forming carbon-carbon bonds
XppCFBP412P_21660	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
XppCFBP412P_21670	COG1324	tolerance protein
XppCFBP412P_21690	COG0459	protein refolding
XppCFBP412P_21705	COG3550	peptidyl-serine autophosphorylation
XppCFBP412P_21710	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
XppCFBP412P_21725	COG3386	PFAM SMP-30 Gluconolaconase
XppCFBP412P_21735	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
XppCFBP412P_21740	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
XppCFBP412P_21760	COG3039	Transposase
XppCFBP412P_21780	COG0778	Nitroreductase
XppCFBP412P_21785	COG2353	YceI-like domain
XppCFBP412P_21820	COG3052	prosthetic group binding
XppCFBP412P_21845	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
XppCFBP412P_21855	COG1802	Transcriptional regulator
XppCFBP412P_21905	COG3328	transposase activity
XppCFBP412P_21915	COG4221	oxidoreductase activity
XppCFBP412P_21945	COG4221	oxidoreductase activity
XppCFBP412P_21955	COG0435	Glutathione S-transferase
XppCFBP412P_22025	COG1959	2 iron, 2 sulfur cluster binding
XppCFBP412P_22050	COG0697	spore germination
XppCFBP412P_22055	COG4305	rare lipoprotein A
XppCFBP412P_22060	COG5297	Belongs to the glycosyl hydrolase family 6
XppCFBP412P_22070	COG1113	amino acid transport
XppCFBP412P_22080	COG0598	Magnesium transport protein CorA
XppCFBP412P_22125	COG5001	Diguanylate cyclase
XppCFBP412P_22125	COG5002	protein histidine kinase activity
XppCFBP412P_22125	COG3447	MASE1 domain protein
XppCFBP412P_22140	COG2205	protein histidine kinase activity
XppCFBP412P_22140	COG0784	Response regulator, receiver
XppCFBP412P_22180	COG2943	transferase activity, transferring hexosyl groups
XppCFBP412P_22190	COG3275	phosphorelay sensor kinase activity
XppCFBP412P_22200	COG0181	hydroxymethylbilane synthase activity
XppCFBP412P_22240	COG1505	serine-type exopeptidase activity
XppCFBP412P_22250	COG0436	Aminotransferase
XppCFBP412P_22260	COG2832	Protein of unknown function (DUF454)
XppCFBP412P_22270	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
XppCFBP412P_22280	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
XppCFBP412P_22285	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
XppCFBP412P_22290	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
XppCFBP412P_22320	COG2226	methyltransferase
XppCFBP412P_22325	COG5001	Diguanylate cyclase
XppCFBP412P_22325	COG3300	MHYT domain
XppCFBP412P_22330	COG0308	aminopeptidase N
XppCFBP412P_22380	COG3284	Transcriptional regulator
XppCFBP412P_22485	COG4962	Type ii secretion system protein e
XppCFBP412P_22510	COG3846	protein secretion by the type IV secretion system
XppCFBP412P_22545	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
XppCFBP412P_22545	COG0551	DNA topoisomerase type I activity
XppCFBP412P_22565	COG2951	lytic endotransglycosylase activity
XppCFBP412P_22615	COG3328	transposase activity
XppCFBP412P_22705	COG1487	ribonuclease activity
XppCFBP412P_22710	COG4691	Plasmid stability protein
XppCFBP412P_22715	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
XppCFBP412P_22875	COG3328	transposase activity
XppCFBP412P_22980	COG3328	transposase activity
XppCFBP412P_23000	COG1192	Involved in chromosome partitioning
XppCFBP412P_23045	COG3012	SEC-C Motif Domain Protein
XppCFBP412P_23045	COG3318	Belongs to the UPF0149 family
XppCFBP412P_23285	COG2201	protein-glutamate methylesterase activity