locus-tag	class	description
XppCFBP6546P_00005	COG1611	Belongs to the LOG family
XppCFBP6546P_00085	COG4695	Portal protein
XppCFBP6546P_00130	COG3179	chitinase
XppCFBP6546P_00300	COG0556	nucleotide-excision repair
XppCFBP6546P_00315	COG3505	Type IV secretory pathway VirD4
XppCFBP6546P_00335	COG2948	multi-organism process
XppCFBP6546P_00355	COG3702	type iv secretory pathway
XppCFBP6546P_00440	COG0326	Molecular chaperone. Has ATPase activity
XppCFBP6546P_00445	COG0742	ribosomal rna small subunit methyltransferase
XppCFBP6546P_00450	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
XppCFBP6546P_00465	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
XppCFBP6546P_00520	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
XppCFBP6546P_00525	COG0343	queuine tRNA-ribosyltransferase activity
XppCFBP6546P_00530	COG1862	Preprotein translocase
XppCFBP6546P_00540	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
XppCFBP6546P_00550	COG3328	transposase activity
XppCFBP6546P_00565	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
XppCFBP6546P_00565	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
XppCFBP6546P_00570	COG1105	Belongs to the carbohydrate kinase PfkB family
XppCFBP6546P_00575	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
XppCFBP6546P_00575	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
XppCFBP6546P_00580	COG1609	Transcriptional regulator
XppCFBP6546P_00585	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XppCFBP6546P_00590	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XppCFBP6546P_00600	COG2902	Dehydrogenase
XppCFBP6546P_00630	COG0840	transmembrane signaling receptor activity
XppCFBP6546P_00635	COG0477	Major facilitator Superfamily
XppCFBP6546P_00645	COG5002	protein histidine kinase activity
XppCFBP6546P_00645	COG0784	Response regulator, receiver
XppCFBP6546P_00645	COG2205	protein histidine kinase activity
XppCFBP6546P_00650	COG2733	membrane
XppCFBP6546P_00680	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
XppCFBP6546P_00685	COG0243	molybdopterin cofactor binding
XppCFBP6546P_00695	COG0477	Major facilitator Superfamily
XppCFBP6546P_00700	COG2703	oxygen carrier activity
XppCFBP6546P_00705	COG3706	GGDEF domain
XppCFBP6546P_00705	COG0745	RESPONSE REGULATOR receiver
XppCFBP6546P_00710	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XppCFBP6546P_00715	COG0174	glutamine synthetase
XppCFBP6546P_00720	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
XppCFBP6546P_00735	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
XppCFBP6546P_00755	COG3842	ATPase activity
XppCFBP6546P_00760	COG1176	ABC-type spermidine putrescine transport system, permease component I
XppCFBP6546P_00765	COG1177	transmembrane transport
XppCFBP6546P_00770	COG1012	belongs to the aldehyde dehydrogenase family
XppCFBP6546P_00785	COG4535	Mg2 and Co2 transporter CorC
XppCFBP6546P_00795	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
XppCFBP6546P_00805	COG1702	phosphate starvation-inducible protein PhoH
XppCFBP6546P_00810	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
XppCFBP6546P_00825	COG0741	lytic transglycosylase activity
XppCFBP6546P_00835	COG0723	plastoquinol--plastocyanin reductase activity
XppCFBP6546P_00840	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
XppCFBP6546P_00845	COG2857	Cytochrome c1
XppCFBP6546P_00850	COG0625	glutathione transferase activity
XppCFBP6546P_00855	COG2969	positive regulation of protein catabolic process
XppCFBP6546P_00875	COG1201	RNA secondary structure unwinding
XppCFBP6546P_00880	COG2094	Belongs to the DNA glycosylase MPG family
XppCFBP6546P_00885	COG0840	transmembrane signaling receptor activity
XppCFBP6546P_00890	COG0835	chemotaxis
XppCFBP6546P_00935	COG1262	PFAM Formylglycine-generating sulfatase enzyme
XppCFBP6546P_00950	COG1570	exodeoxyribonuclease VII activity
XppCFBP6546P_00955	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
XppCFBP6546P_00960	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
XppCFBP6546P_00960	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
XppCFBP6546P_00965	COG0802	atpase or kinase
XppCFBP6546P_00970	COG0860	N-Acetylmuramoyl-L-alanine amidase
XppCFBP6546P_00975	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
XppCFBP6546P_01000	COG1028	Short-chain dehydrogenase reductase Sdr
XppCFBP6546P_01005	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
XppCFBP6546P_01010	COG0501	Belongs to the peptidase M48B family
XppCFBP6546P_01020	COG2081	HI0933 family
XppCFBP6546P_01025	COG4681	YaeQ
XppCFBP6546P_01035	COG0625	glutathione transferase activity
XppCFBP6546P_01055	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
XppCFBP6546P_01060	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
XppCFBP6546P_01065	COG0513	Belongs to the DEAD box helicase family
XppCFBP6546P_01090	COG0483	inositol monophosphate 1-phosphatase activity
XppCFBP6546P_01105	COG3300	MHYT domain
XppCFBP6546P_01105	COG5001	Diguanylate cyclase
XppCFBP6546P_01110	COG1509	lysine 2,3-aminomutase activity
XppCFBP6546P_01115	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
XppCFBP6546P_01125	COG0402	S-adenosylhomocysteine deaminase activity
XppCFBP6546P_01130	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
XppCFBP6546P_01160	COG3039	Transposase
XppCFBP6546P_01190	COG4302	ethanolamine ammonia-lyase activity
XppCFBP6546P_01220	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
XppCFBP6546P_01225	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
XppCFBP6546P_01230	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
XppCFBP6546P_01240	COG2166	iron-sulfur cluster assembly
XppCFBP6546P_01245	COG0215	cysteine-tRNA ligase activity
XppCFBP6546P_01255	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
XppCFBP6546P_01260	COG0137	argininosuccinate synthase activity
XppCFBP6546P_01285	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
XppCFBP6546P_01290	COG0165	Argininosuccinate lyase
XppCFBP6546P_01300	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
XppCFBP6546P_01305	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
XppCFBP6546P_01335	COG1294	oxidase, subunit
XppCFBP6546P_01345	COG4988	ABC transporter
XppCFBP6546P_01350	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
XppCFBP6546P_01360	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XppCFBP6546P_01385	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
XppCFBP6546P_01405	COG4133	protoheme IX ABC transporter activity
XppCFBP6546P_01410	COG0436	Aminotransferase
XppCFBP6546P_01415	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XppCFBP6546P_01430	COG1187	pseudouridine synthase activity
XppCFBP6546P_01435	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
XppCFBP6546P_01445	COG2350	Protein conserved in bacteria
XppCFBP6546P_01480	COG1175	transmembrane transport
XppCFBP6546P_01485	COG0395	ABC-type sugar transport system, permease component
XppCFBP6546P_01510	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XppCFBP6546P_01525	COG0257	Belongs to the bacterial ribosomal protein bL36 family
XppCFBP6546P_01530	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
XppCFBP6546P_01535	COG0539	negative regulation of cytoplasmic translation
XppCFBP6546P_01540	COG0776	regulation of translation
XppCFBP6546P_01550	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
XppCFBP6546P_01555	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
XppCFBP6546P_01565	COG1210	Utp--glucose-1-phosphate uridylyltransferase
XppCFBP6546P_01570	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
XppCFBP6546P_01570	COG0475	glutathione-regulated potassium exporter activity
XppCFBP6546P_01580	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
XppCFBP6546P_01590	COG0518	GMP synthase (glutamine-hydrolyzing) activity
XppCFBP6546P_01590	COG0519	Catalyzes the synthesis of GMP from XMP
XppCFBP6546P_01650	COG3384	dioxygenase
XppCFBP6546P_01655	COG0604	alcohol dehydrogenase
XppCFBP6546P_01665	COG3002	Belongs to the UPF0753 family
XppCFBP6546P_01670	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
XppCFBP6546P_01675	COG0583	DNA-binding transcription factor activity
XppCFBP6546P_01700	COG2197	response regulator
XppCFBP6546P_01720	COG1335	isochorismatase
XppCFBP6546P_01735	COG2814	Major facilitator Superfamily
XppCFBP6546P_01755	COG1914	H( )-stimulated, divalent metal cation uptake system
XppCFBP6546P_01760	COG1321	iron dependent repressor
XppCFBP6546P_01765	COG0590	tRNA wobble adenosine to inosine editing
XppCFBP6546P_01770	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
XppCFBP6546P_01785	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
XppCFBP6546P_01800	COG1028	Short-chain dehydrogenase reductase Sdr
XppCFBP6546P_01805	COG1183	phosphatidylcholine synthase activity
XppCFBP6546P_01815	COG3243	poly(R)-hydroxyalkanoic acid synthase
XppCFBP6546P_01830	COG0723	plastoquinol--plastocyanin reductase activity
XppCFBP6546P_01830	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XppCFBP6546P_01840	COG2183	response to ionizing radiation
XppCFBP6546P_01845	COG2205	protein histidine kinase activity
XppCFBP6546P_01845	COG0784	Response regulator, receiver
XppCFBP6546P_01910	COG0800	Aldolase
XppCFBP6546P_01915	COG0129	dihydroxy-acid dehydratase activity
XppCFBP6546P_01920	COG0363	glucosamine-6-phosphate deaminase activity
XppCFBP6546P_01925	COG0837	glucose binding
XppCFBP6546P_01930	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
XppCFBP6546P_01940	COG0354	folic acid binding
XppCFBP6546P_01955	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
XppCFBP6546P_01970	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
XppCFBP6546P_01975	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
XppCFBP6546P_01985	COG4591	ABC-type transport system involved in lipoprotein release permease component
XppCFBP6546P_01990	COG1136	(ABC) transporter
XppCFBP6546P_02005	COG0811	peptide transport
XppCFBP6546P_02015	COG1132	(ABC) transporter
XppCFBP6546P_02020	COG1663	tetraacyldisaccharide 4'-kinase activity
XppCFBP6546P_02025	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
XppCFBP6546P_02030	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
XppCFBP6546P_02040	COG0322	excinuclease ABC activity
XppCFBP6546P_02045	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
XppCFBP6546P_02070	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
XppCFBP6546P_02100	COG3039	Transposase
XppCFBP6546P_02115	COG3064	Membrane
XppCFBP6546P_02120	COG0428	transporter
XppCFBP6546P_02130	COG2154	pterin-4-alpha-carbinolamine dehydratase
XppCFBP6546P_02145	COG1309	transcriptional regulator
XppCFBP6546P_02180	COG3328	transposase activity
XppCFBP6546P_02225	COG3012	SEC-C Motif Domain Protein
XppCFBP6546P_02225	COG3318	Belongs to the UPF0149 family
XppCFBP6546P_02285	COG3328	transposase activity
XppCFBP6546P_02325	COG3328	transposase activity
XppCFBP6546P_02425	COG0363	glucosamine-6-phosphate deaminase activity
XppCFBP6546P_02440	COG2226	methyltransferase
XppCFBP6546P_02440	COG1073	alpha beta
XppCFBP6546P_02450	COG3328	transposase activity
XppCFBP6546P_02540	COG3328	transposase activity
XppCFBP6546P_02545	COG3039	Transposase
XppCFBP6546P_02555	COG3328	transposase activity
XppCFBP6546P_02610	COG4566	intracellular signal transduction
XppCFBP6546P_02620	COG5001	Diguanylate cyclase
XppCFBP6546P_02640	COG3685	Protein conserved in bacteria
XppCFBP6546P_02655	COG0243	molybdopterin cofactor binding
XppCFBP6546P_02670	COG2223	nitrite transmembrane transporter activity
XppCFBP6546P_02675	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
XppCFBP6546P_02685	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
XppCFBP6546P_02685	COG1648	precorrin-2 dehydrogenase activity
XppCFBP6546P_02710	COG0746	molybdenum cofactor guanylyltransferase activity
XppCFBP6546P_02715	COG0303	'Molybdopterin
XppCFBP6546P_02725	COG0708	Exodeoxyribonuclease III
XppCFBP6546P_02760	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
XppCFBP6546P_02765	COG0303	'Molybdopterin
XppCFBP6546P_02770	COG1160	GTP binding
XppCFBP6546P_02775	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XppCFBP6546P_02800	COG0105	UTP biosynthetic process
XppCFBP6546P_02810	COG1250	3-hydroxyacyl-CoA dehydrogenase
XppCFBP6546P_02810	COG1024	Enoyl-CoA hydratase
XppCFBP6546P_02815	COG0183	Belongs to the thiolase family
XppCFBP6546P_02820	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
XppCFBP6546P_02825	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
XppCFBP6546P_02835	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
XppCFBP6546P_02845	COG1674	ftsk spoiiie
XppCFBP6546P_02850	COG0492	ferredoxin-NADP+ reductase activity
XppCFBP6546P_02860	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
XppCFBP6546P_02865	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
XppCFBP6546P_02870	COG0542	response to heat
XppCFBP6546P_02875	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
XppCFBP6546P_02885	COG0482	sulfurtransferase activity
XppCFBP6546P_02890	COG2915	High frequency lysogenization protein hflD homolog
XppCFBP6546P_02910	COG4585	Histidine kinase
XppCFBP6546P_02920	COG5002	protein histidine kinase activity
XppCFBP6546P_02940	COG0784	Response regulator, receiver
XppCFBP6546P_02940	COG0835	chemotaxis
XppCFBP6546P_02950	COG1558	bacterial-type flagellum-dependent cell motility
XppCFBP6546P_02955	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
XppCFBP6546P_02960	COG1749	Flagellar hook protein flgE
XppCFBP6546P_02965	COG4787	bacterial-type flagellum-dependent cell motility
XppCFBP6546P_02985	COG3858	chitin binding
XppCFBP6546P_02985	COG1388	LysM domain
XppCFBP6546P_02990	COG3525	Glycosyl hydrolase, family 20, catalytic domain
XppCFBP6546P_03000	COG1472	Belongs to the glycosyl hydrolase 3 family
XppCFBP6546P_03010	COG3537	Alpha-1,2-mannosidase
XppCFBP6546P_03055	COG3142	Participates in the control of copper homeostasis
XppCFBP6546P_03060	COG1446	asparaginase
XppCFBP6546P_03095	COG0840	transmembrane signaling receptor activity
XppCFBP6546P_03115	COG0189	ligase activity
XppCFBP6546P_03125	COG1397	ADP-ribosylglycohydrolase
XppCFBP6546P_03135	COG1199	ATP-dependent helicase activity
XppCFBP6546P_03145	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
XppCFBP6546P_03150	COG1215	transferase activity, transferring glycosyl groups
XppCFBP6546P_03165	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
XppCFBP6546P_03175	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
XppCFBP6546P_03180	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
XppCFBP6546P_03185	COG0535	radical SAM domain protein
XppCFBP6546P_03190	COG0535	radical SAM domain protein
XppCFBP6546P_03205	COG0837	glucose binding
XppCFBP6546P_03215	COG3328	transposase activity
XppCFBP6546P_03225	COG1643	Atp-dependent helicase
XppCFBP6546P_03230	COG0783	Belongs to the Dps family
XppCFBP6546P_03235	COG0514	ATP-dependent DNA helicase (RecQ)
XppCFBP6546P_03270	COG0840	transmembrane signaling receptor activity
XppCFBP6546P_03290	COG3920	Histidine kinase
XppCFBP6546P_03305	COG0602	queuosine metabolic process
XppCFBP6546P_03315	COG2885	chlorophyll binding
XppCFBP6546P_03320	COG0823	Involved in the tonB-independent uptake of proteins
XppCFBP6546P_03330	COG0848	biopolymer transport protein
XppCFBP6546P_03340	COG0824	Thioesterase
XppCFBP6546P_03345	COG2255	four-way junction helicase activity
XppCFBP6546P_03355	COG3158	transport of potassium into the cell
XppCFBP6546P_03360	COG0632	four-way junction helicase activity
XppCFBP6546P_03365	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
XppCFBP6546P_03370	COG0217	transcriptional regulatory protein
XppCFBP6546P_03385	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
XppCFBP6546P_03400	COG0477	Major facilitator Superfamily
XppCFBP6546P_03480	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
XppCFBP6546P_03480	COG4651	solute:proton antiporter activity
XppCFBP6546P_03500	COG0659	secondary active sulfate transmembrane transporter activity
XppCFBP6546P_03525	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
XppCFBP6546P_03530	COG0573	inorganic phosphate transmembrane transporter activity
XppCFBP6546P_03535	COG0581	inorganic phosphate transmembrane transporter activity
XppCFBP6546P_03540	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
XppCFBP6546P_03545	COG0704	Plays a role in the regulation of phosphate uptake
XppCFBP6546P_03555	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
XppCFBP6546P_03570	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
XppCFBP6546P_03580	COG0557	exoribonuclease II activity
XppCFBP6546P_03595	COG1960	acyl-CoA dehydrogenase activity
XppCFBP6546P_03600	COG1960	acyl-CoA dehydrogenase activity
XppCFBP6546P_03625	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XppCFBP6546P_03655	COG2900	Belongs to the SlyX family
XppCFBP6546P_03675	COG0386	Belongs to the glutathione peroxidase family
XppCFBP6546P_03685	COG1725	Transcriptional regulator
XppCFBP6546P_03690	COG1131	(ABC) transporter
XppCFBP6546P_03725	COG1253	flavin adenine dinucleotide binding
XppCFBP6546P_03745	COG2850	peptidyl-arginine hydroxylation
XppCFBP6546P_03780	COG1132	(ABC) transporter
XppCFBP6546P_03785	COG0583	DNA-binding transcription factor activity
XppCFBP6546P_03815	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
XppCFBP6546P_03820	COG0484	heat shock protein binding
XppCFBP6546P_03825	COG0443	Heat shock 70 kDa protein
XppCFBP6546P_03830	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
XppCFBP6546P_03835	COG1420	regulation of RNA biosynthetic process
XppCFBP6546P_03840	COG0497	DNA recombination
XppCFBP6546P_03850	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XppCFBP6546P_03865	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
XppCFBP6546P_03885	COG3706	GGDEF domain
XppCFBP6546P_03895	COG3706	GGDEF domain
XppCFBP6546P_03930	COG0583	DNA-binding transcription factor activity
XppCFBP6546P_03940	COG0415	Belongs to the DNA photolyase family
XppCFBP6546P_03945	COG0305	Participates in initiation and elongation during chromosome replication
XppCFBP6546P_03955	COG0367	asparagine synthase
XppCFBP6546P_03975	COG1960	acyl-CoA dehydrogenase activity
XppCFBP6546P_03990	COG0084	hydrolase, TatD family'
XppCFBP6546P_03995	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
XppCFBP6546P_04055	COG0386	Belongs to the glutathione peroxidase family
XppCFBP6546P_04060	COG0339	signal peptide processing
XppCFBP6546P_04120	COG2814	Major facilitator Superfamily
XppCFBP6546P_04125	COG1566	PFAM secretion protein HlyD family protein
XppCFBP6546P_04185	COG2963	transposase activity
XppCFBP6546P_04225	COG4774	siderophore transport
XppCFBP6546P_04235	COG0367	asparagine synthase
XppCFBP6546P_04240	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XppCFBP6546P_04245	COG1393	Belongs to the ArsC family
XppCFBP6546P_04255	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
XppCFBP6546P_04260	COG0024	Methionine aminopeptidase
XppCFBP6546P_04295	COG0052	Belongs to the universal ribosomal protein uS2 family
XppCFBP6546P_04300	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
XppCFBP6546P_04305	COG3706	GGDEF domain
XppCFBP6546P_04305	COG0745	RESPONSE REGULATOR receiver
XppCFBP6546P_04310	COG0528	UMP kinase activity
XppCFBP6546P_04315	COG0233	cytoplasmic translational termination
XppCFBP6546P_04320	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
XppCFBP6546P_04325	COG0575	Belongs to the CDS family
XppCFBP6546P_04335	COG0750	zinc metalloprotease
XppCFBP6546P_04350	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XppCFBP6546P_04355	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
XppCFBP6546P_04360	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XppCFBP6546P_04365	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XppCFBP6546P_04380	COG0825	malonyl-CoA metabolic process
XppCFBP6546P_04415	COG1695	Transcriptional regulator
XppCFBP6546P_04435	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
XppCFBP6546P_04445	COG2040	homocysteine
XppCFBP6546P_04450	COG0833	amino acid
XppCFBP6546P_04465	COG0346	lactoylglutathione lyase activity
XppCFBP6546P_04485	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
XppCFBP6546P_04485	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
XppCFBP6546P_04495	COG2878	Part of a membrane complex involved in electron transport
XppCFBP6546P_04510	COG1595	DNA-templated transcription, initiation
XppCFBP6546P_04535	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
XppCFBP6546P_04550	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
XppCFBP6546P_04555	COG0251	oxidation-reduction process
XppCFBP6546P_04565	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
XppCFBP6546P_04565	COG0392	lysyltransferase activity
XppCFBP6546P_04595	COG2814	Major facilitator Superfamily
XppCFBP6546P_04600	COG1902	pentaerythritol trinitrate reductase activity
XppCFBP6546P_04610	COG2824	Alkylphosphonate utilization operon protein PhnA
XppCFBP6546P_04620	COG1047	Peptidyl-prolyl cis-trans
XppCFBP6546P_04625	COG1077	Cell shape determining protein MreB Mrl
XppCFBP6546P_04645	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
XppCFBP6546P_04655	COG5487	UPF0391 membrane protein
XppCFBP6546P_04660	COG1451	nucleotide metabolic process
XppCFBP6546P_04680	COG0183	Belongs to the thiolase family
XppCFBP6546P_04700	COG0745	RESPONSE REGULATOR receiver
XppCFBP6546P_04700	COG3706	GGDEF domain
XppCFBP6546P_04720	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
XppCFBP6546P_04720	COG1793	dna ligase
XppCFBP6546P_04730	COG1793	dna ligase
XppCFBP6546P_04735	COG1201	RNA secondary structure unwinding
XppCFBP6546P_04750	COG1278	Cold shock
XppCFBP6546P_04755	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
XppCFBP6546P_04765	COG1472	Belongs to the glycosyl hydrolase 3 family
XppCFBP6546P_04770	COG3046	protein related to deoxyribodipyrimidine photolyase
XppCFBP6546P_04775	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
XppCFBP6546P_04780	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
XppCFBP6546P_04790	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
XppCFBP6546P_04800	COG1381	Involved in DNA repair and RecF pathway recombination
XppCFBP6546P_04805	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
XppCFBP6546P_04810	COG0571	ribonuclease III activity
XppCFBP6546P_04825	COG0481	GTPase activity
XppCFBP6546P_04830	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XppCFBP6546P_04845	COG1250	3-hydroxyacyl-CoA dehydrogenase
XppCFBP6546P_04845	COG1024	Enoyl-CoA hydratase
XppCFBP6546P_04855	COG0457	Tetratricopeptide repeat
XppCFBP6546P_04865	COG0457	Tetratricopeptide repeat
XppCFBP6546P_04895	COG1960	acyl-CoA dehydrogenase activity
XppCFBP6546P_04915	COG3867	Arabinogalactan endo-beta-1,4-galactanase
XppCFBP6546P_04920	COG3250	beta-galactosidase activity
XppCFBP6546P_04965	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
XppCFBP6546P_04980	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
XppCFBP6546P_05005	COG0534	Mate efflux family protein
XppCFBP6546P_05010	COG0335	large ribosomal subunit rRNA binding
XppCFBP6546P_05015	COG0336	Belongs to the RNA methyltransferase TrmD family
XppCFBP6546P_05020	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
XppCFBP6546P_05025	COG0228	four-way junction DNA binding
XppCFBP6546P_05030	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
XppCFBP6546P_05040	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
XppCFBP6546P_05065	COG0784	Response regulator, receiver
XppCFBP6546P_05065	COG4191	Histidine kinase
XppCFBP6546P_05070	COG2205	protein histidine kinase activity
XppCFBP6546P_05070	COG3437	response regulator, receiver
XppCFBP6546P_05070	COG3850	Histidine kinase
XppCFBP6546P_05070	COG4999	Histidine kinase
XppCFBP6546P_05075	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
XppCFBP6546P_05085	COG2205	protein histidine kinase activity
XppCFBP6546P_05090	COG5507	3-demethylubiquinone-9 3-methyltransferase
XppCFBP6546P_05100	COG4771	TonB-dependent receptor
XppCFBP6546P_05130	COG1366	Belongs to the anti-sigma-factor antagonist family
XppCFBP6546P_05135	COG1366	Belongs to the anti-sigma-factor antagonist family
XppCFBP6546P_05145	COG0326	Molecular chaperone. Has ATPase activity
XppCFBP6546P_05150	COG2207	Transcriptional regulator
XppCFBP6546P_05160	COG3152	Membrane
XppCFBP6546P_05175	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
XppCFBP6546P_05180	COG1845	cytochrome c oxidase, subunit III
XppCFBP6546P_05185	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
XppCFBP6546P_05200	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
XppCFBP6546P_05205	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
XppCFBP6546P_05210	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
XppCFBP6546P_05215	COG0196	riboflavin kinase activity
XppCFBP6546P_05225	COG0268	Binds directly to 16S ribosomal RNA
XppCFBP6546P_05230	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
XppCFBP6546P_05235	COG0211	Belongs to the bacterial ribosomal protein bL27 family
XppCFBP6546P_05240	COG0261	This protein binds to 23S rRNA in the presence of protein L20
XppCFBP6546P_05245	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
XppCFBP6546P_05250	COG0824	Thioesterase
XppCFBP6546P_05265	COG1946	Acyl-CoA thioesterase
XppCFBP6546P_05275	COG1595	DNA-templated transcription, initiation
XppCFBP6546P_05290	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
XppCFBP6546P_05300	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
XppCFBP6546P_05325	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
XppCFBP6546P_05340	COG2197	response regulator
XppCFBP6546P_05345	COG4585	Histidine kinase
XppCFBP6546P_05360	COG0850	regulation of cytokinetic process
XppCFBP6546P_05365	COG2894	cell division
XppCFBP6546P_05370	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
XppCFBP6546P_05380	COG0642	Histidine kinase
XppCFBP6546P_05385	COG0745	RESPONSE REGULATOR receiver
XppCFBP6546P_05400	COG2194	sulfuric ester hydrolase activity
XppCFBP6546P_05430	COG2814	Major facilitator Superfamily
XppCFBP6546P_05455	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
XppCFBP6546P_05455	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
XppCFBP6546P_05465	COG0656	L-ascorbic acid biosynthetic process
XppCFBP6546P_05485	COG3328	transposase activity
XppCFBP6546P_05495	COG2207	Transcriptional regulator
XppCFBP6546P_05495	COG1917	Cupin 2, conserved barrel domain protein
XppCFBP6546P_05515	COG2963	transposase activity
XppCFBP6546P_05525	COG0823	Involved in the tonB-independent uptake of proteins
XppCFBP6546P_05525	COG1506	peptidase
XppCFBP6546P_05545	COG1297	OPT oligopeptide transporter protein
XppCFBP6546P_05580	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
XppCFBP6546P_05615	COG2080	2 iron, 2 sulfur cluster binding
XppCFBP6546P_05620	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
XppCFBP6546P_05625	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XppCFBP6546P_05675	COG3537	Alpha-1,2-mannosidase
XppCFBP6546P_05685	COG1028	Short-chain dehydrogenase reductase Sdr
XppCFBP6546P_05690	COG3387	PFAM Glycoside hydrolase 15-related
XppCFBP6546P_05700	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
XppCFBP6546P_05740	COG3328	transposase activity
XppCFBP6546P_05770	COG1028	Short-chain dehydrogenase reductase Sdr
XppCFBP6546P_05780	COG0308	aminopeptidase N
XppCFBP6546P_05785	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
XppCFBP6546P_05795	COG0330	HflC and HflK could
XppCFBP6546P_05800	COG0330	HflC and HflK could
XppCFBP6546P_05820	COG0678	peroxiredoxin activity
XppCFBP6546P_05830	COG4953	penicillin-binding protein 1C
XppCFBP6546P_05835	COG3852	Histidine kinase
XppCFBP6546P_05855	COG2373	Large extracellular alpha-helical protein
XppCFBP6546P_05905	COG3829	transcription factor binding
XppCFBP6546P_05940	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
XppCFBP6546P_05955	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
XppCFBP6546P_05960	COG1028	Short-chain dehydrogenase reductase Sdr
XppCFBP6546P_05975	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XppCFBP6546P_05980	COG0333	Belongs to the bacterial ribosomal protein bL32 family
XppCFBP6546P_05985	COG1399	metal-binding, possibly nucleic acid-binding protein
XppCFBP6546P_05990	COG0424	maF-like protein
XppCFBP6546P_06025	COG0537	adenosine 5'-monophosphoramidase activity
XppCFBP6546P_06030	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
XppCFBP6546P_06035	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
XppCFBP6546P_06055	COG0314	molybdopterin synthase activity
XppCFBP6546P_06060	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
XppCFBP6546P_06065	COG0315	cyclic pyranopterin monophosphate synthase activity
XppCFBP6546P_06075	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
XppCFBP6546P_06080	COG1234	tRNA 3'-trailer cleavage
XppCFBP6546P_06085	COG3642	lipopolysaccharide core region biosynthetic process
XppCFBP6546P_06090	COG0859	PFAM glycosyl transferase family 9
XppCFBP6546P_06115	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
XppCFBP6546P_06120	COG0328	RNA-DNA hybrid ribonuclease activity
XppCFBP6546P_06130	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XppCFBP6546P_06140	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
XppCFBP6546P_06170	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
XppCFBP6546P_06175	COG0740	serine-type endopeptidase activity
XppCFBP6546P_06180	COG0544	peptidyl-prolyl cis-trans isomerase activity
XppCFBP6546P_06195	COG3328	transposase activity
XppCFBP6546P_06235	COG0473	3-isopropylmalate dehydrogenase activity
XppCFBP6546P_06250	COG4783	chaperone-mediated protein folding
XppCFBP6546P_06265	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
XppCFBP6546P_06280	COG0671	phosphoesterase, PA-phosphatase related
XppCFBP6546P_06285	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XppCFBP6546P_06305	COG2833	Protein of unknown function (DUF455)
XppCFBP6546P_06325	COG0285	dihydrofolate synthase activity
XppCFBP6546P_06335	COG0406	alpha-ribazole phosphatase activity
XppCFBP6546P_06355	COG1063	alcohol dehydrogenase
XppCFBP6546P_06360	COG3328	transposase activity
XppCFBP6546P_06370	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
XppCFBP6546P_06375	COG4208	sulfate ABC transporter
XppCFBP6546P_06380	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
XppCFBP6546P_06385	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
XppCFBP6546P_06390	COG0156	8-amino-7-oxononanoate synthase activity
XppCFBP6546P_06410	COG2885	chlorophyll binding
XppCFBP6546P_06415	COG3039	Transposase
XppCFBP6546P_06420	COG3328	transposase activity
XppCFBP6546P_06430	COG0604	alcohol dehydrogenase
XppCFBP6546P_06435	COG1902	pentaerythritol trinitrate reductase activity
XppCFBP6546P_06435	COG0446	pyridine nucleotide-disulphide oxidoreductase
XppCFBP6546P_06455	COG0625	glutathione transferase activity
XppCFBP6546P_06460	COG0039	L-malate dehydrogenase activity
XppCFBP6546P_06465	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
XppCFBP6546P_06490	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
XppCFBP6546P_06510	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
XppCFBP6546P_06515	COG0203	ribosomal protein L17
XppCFBP6546P_06520	COG0202	RNA polymerase activity
XppCFBP6546P_06525	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
XppCFBP6546P_06530	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
XppCFBP6546P_06535	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
XppCFBP6546P_06540	COG0201	protein transport
XppCFBP6546P_06545	COG0200	Binds to the 23S rRNA
XppCFBP6546P_06550	COG1841	ribosomal large subunit assembly
XppCFBP6546P_06555	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
XppCFBP6546P_06560	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
XppCFBP6546P_06565	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
XppCFBP6546P_06570	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
XppCFBP6546P_06575	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
XppCFBP6546P_06580	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
XppCFBP6546P_06585	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
XppCFBP6546P_06590	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
XppCFBP6546P_06595	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
XppCFBP6546P_06600	COG0255	Belongs to the universal ribosomal protein uL29 family
XppCFBP6546P_06605	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
XppCFBP6546P_06610	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
XppCFBP6546P_06615	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
XppCFBP6546P_06620	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
XppCFBP6546P_06625	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
XppCFBP6546P_06630	COG0089	rRNA binding
XppCFBP6546P_06635	COG0088	Forms part of the polypeptide exit tunnel
XppCFBP6546P_06640	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
XppCFBP6546P_06645	COG0051	transcription antitermination factor activity, RNA binding
XppCFBP6546P_06650	COG3328	transposase activity
XppCFBP6546P_06665	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
XppCFBP6546P_06670	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
XppCFBP6546P_06675	COG0049	tRNA binding
XppCFBP6546P_06680	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
XppCFBP6546P_06685	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
XppCFBP6546P_06690	COG0085	RNA polymerase activity
XppCFBP6546P_06700	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
XppCFBP6546P_06705	COG0081	regulation of translation
XppCFBP6546P_06710	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
XppCFBP6546P_06715	COG0250	Participates in transcription elongation, termination and antitermination
XppCFBP6546P_06720	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
XppCFBP6546P_06730	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
XppCFBP6546P_06750	COG0012	GTP binding
XppCFBP6546P_06755	COG0193	aminoacyl-tRNA hydrolase activity
XppCFBP6546P_06760	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
XppCFBP6546P_06765	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
XppCFBP6546P_06775	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
XppCFBP6546P_06780	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
XppCFBP6546P_06790	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
XppCFBP6546P_06795	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
XppCFBP6546P_06805	COG0521	Mo-molybdopterin cofactor biosynthetic process
XppCFBP6546P_06820	COG1254	Belongs to the acylphosphatase family
XppCFBP6546P_06825	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XppCFBP6546P_06830	COG1295	ribonuclease BN
XppCFBP6546P_06855	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
XppCFBP6546P_06860	COG1404	Belongs to the peptidase S8 family
XppCFBP6546P_06865	COG1404	Belongs to the peptidase S8 family
XppCFBP6546P_06875	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
XppCFBP6546P_06895	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
XppCFBP6546P_06935	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
XppCFBP6546P_06935	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
XppCFBP6546P_06955	COG2890	protein-(glutamine-N5) methyltransferase activity
XppCFBP6546P_06965	COG3634	alkyl hydroperoxide reductase activity
XppCFBP6546P_06970	COG0583	DNA-binding transcription factor activity
XppCFBP6546P_06980	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XppCFBP6546P_06985	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
XppCFBP6546P_07000	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
XppCFBP6546P_07010	COG2197	response regulator
XppCFBP6546P_07020	COG3706	GGDEF domain
XppCFBP6546P_07020	COG0745	RESPONSE REGULATOR receiver
XppCFBP6546P_07035	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
XppCFBP6546P_07045	COG0697	spore germination
XppCFBP6546P_07065	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
XppCFBP6546P_07075	COG3386	PFAM SMP-30 Gluconolaconase
XppCFBP6546P_07095	COG1024	Enoyl-CoA hydratase
XppCFBP6546P_07105	COG0318	PFAM AMP-dependent synthetase and ligase
XppCFBP6546P_07110	COG0583	DNA-binding transcription factor activity
XppCFBP6546P_07115	COG3384	dioxygenase
XppCFBP6546P_07145	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XppCFBP6546P_07150	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XppCFBP6546P_07165	COG2096	Adenosyltransferase
XppCFBP6546P_07170	COG0123	including yeast histone deacetylase and acetoin utilization protein
XppCFBP6546P_07185	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
XppCFBP6546P_07190	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
XppCFBP6546P_07195	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
XppCFBP6546P_07205	COG2967	ApaG domain
XppCFBP6546P_07210	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
XppCFBP6546P_07225	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
XppCFBP6546P_07230	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
XppCFBP6546P_07240	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
XppCFBP6546P_07250	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
XppCFBP6546P_07275	COG4181	ATPase activity
XppCFBP6546P_07285	COG2175	clavaminate synthase activity
XppCFBP6546P_07295	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
XppCFBP6546P_07300	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XppCFBP6546P_07320	COG4771	TonB-dependent receptor
XppCFBP6546P_07330	COG0667	Aldo Keto reductase
XppCFBP6546P_07335	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
XppCFBP6546P_07340	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XppCFBP6546P_07355	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
XppCFBP6546P_07360	COG4106	trans-aconitate 2-methyltransferase activity
XppCFBP6546P_07370	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
XppCFBP6546P_07410	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
XppCFBP6546P_07420	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
XppCFBP6546P_07425	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
XppCFBP6546P_07470	COG3321	synthase
XppCFBP6546P_07470	COG1028	Short-chain dehydrogenase reductase Sdr
XppCFBP6546P_07470	COG0604	alcohol dehydrogenase
XppCFBP6546P_07480	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
XppCFBP6546P_07490	COG0494	nUDIX hydrolase
XppCFBP6546P_07495	COG0653	protein targeting
XppCFBP6546P_07500	COG0739	heme binding
XppCFBP6546P_07510	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
XppCFBP6546P_07525	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
XppCFBP6546P_07530	COG1181	Belongs to the D-alanine--D-alanine ligase family
XppCFBP6546P_07535	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
XppCFBP6546P_07540	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
XppCFBP6546P_07550	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
XppCFBP6546P_07555	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
XppCFBP6546P_07560	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
XppCFBP6546P_07570	COG3116	cell division
XppCFBP6546P_07580	COG2001	Belongs to the MraZ family
XppCFBP6546P_07615	COG0792	nuclease activity
XppCFBP6546P_07620	COG1988	membrane-bound metal-dependent
XppCFBP6546P_07625	COG0277	FAD linked oxidase domain protein
XppCFBP6546P_07650	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
XppCFBP6546P_07655	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
XppCFBP6546P_07675	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
XppCFBP6546P_07680	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
XppCFBP6546P_07685	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
XppCFBP6546P_07705	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
XppCFBP6546P_07705	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
XppCFBP6546P_07715	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
XppCFBP6546P_07720	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
XppCFBP6546P_07730	COG0488	(ABC) transporter
XppCFBP6546P_07735	COG0242	peptide deformylase activity
XppCFBP6546P_07760	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
XppCFBP6546P_07765	COG1215	transferase activity, transferring glycosyl groups
XppCFBP6546P_07770	COG1215	transferase activity, transferring glycosyl groups
XppCFBP6546P_07845	COG2188	Transcriptional regulator
XppCFBP6546P_07855	COG1450	Type ii and iii secretion system protein
XppCFBP6546P_07870	COG3166	PFAM Fimbrial assembly family protein
XppCFBP6546P_07875	COG3156	type II secretion system protein K
XppCFBP6546P_07880	COG4795	General secretion pathway protein
XppCFBP6546P_07885	COG2165	general secretion pathway protein
XppCFBP6546P_07890	COG4970	Tfp pilus assembly protein FimT
XppCFBP6546P_07895	COG2165	general secretion pathway protein
XppCFBP6546P_07900	COG1459	type II secretion system
XppCFBP6546P_07905	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
XppCFBP6546P_07910	COG1404	Belongs to the peptidase S8 family
XppCFBP6546P_07915	COG5295	Hep Hag repeat protein
XppCFBP6546P_07920	COG1404	Belongs to the peptidase S8 family
XppCFBP6546P_07925	COG5295	Hep Hag repeat protein
XppCFBP6546P_07930	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
XppCFBP6546P_07930	COG0047	phosphoribosylformylglycinamidine synthase activity
XppCFBP6546P_07940	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
XppCFBP6546P_07955	COG4974	Belongs to the 'phage' integrase family
XppCFBP6546P_07970	COG0795	lipopolysaccharide-transporting ATPase activity
XppCFBP6546P_07980	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
XppCFBP6546P_07995	COG0525	valine-tRNA ligase activity
XppCFBP6546P_08015	COG0617	tRNA 3'-terminal CCA addition
XppCFBP6546P_08025	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
XppCFBP6546P_08030	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
XppCFBP6546P_08035	COG1609	Transcriptional regulator
XppCFBP6546P_08090	COG1459	type II secretion system
XppCFBP6546P_08145	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
XppCFBP6546P_08150	COG4191	Histidine kinase
XppCFBP6546P_08155	COG0784	Response regulator, receiver
XppCFBP6546P_08160	COG4251	negative regulation of phosphorylation
XppCFBP6546P_08165	COG2823	Periplasmic or secreted lipoprotein
XppCFBP6546P_08175	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
XppCFBP6546P_08210	COG1051	belongs to the nudix hydrolase family
XppCFBP6546P_08210	COG1056	cytidyltransferase-related domain
XppCFBP6546P_08235	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
XppCFBP6546P_08240	COG0321	lipoyl(octanoyl) transferase activity
XppCFBP6546P_08245	COG2921	Belongs to the UPF0250 family
XppCFBP6546P_08255	COG1686	Belongs to the peptidase S11 family
XppCFBP6546P_08260	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
XppCFBP6546P_08265	COG2951	lytic endotransglycosylase activity
XppCFBP6546P_08295	COG3039	Transposase
XppCFBP6546P_08310	COG0772	Belongs to the SEDS family
XppCFBP6546P_08325	COG1792	Involved in formation and maintenance of cell shape
XppCFBP6546P_08330	COG1077	Cell shape determining protein MreB Mrl
XppCFBP6546P_08350	COG3284	Transcriptional regulator
XppCFBP6546P_08400	COG0308	aminopeptidase N
XppCFBP6546P_08405	COG5001	Diguanylate cyclase
XppCFBP6546P_08405	COG3300	MHYT domain
XppCFBP6546P_08410	COG2226	methyltransferase
XppCFBP6546P_08440	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
XppCFBP6546P_08445	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
XppCFBP6546P_08450	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
XppCFBP6546P_08460	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
XppCFBP6546P_08470	COG2832	Protein of unknown function (DUF454)
XppCFBP6546P_08490	COG1505	serine-type exopeptidase activity
XppCFBP6546P_08530	COG0181	hydroxymethylbilane synthase activity
XppCFBP6546P_08540	COG3275	phosphorelay sensor kinase activity
XppCFBP6546P_08550	COG2943	transferase activity, transferring hexosyl groups
XppCFBP6546P_08575	COG3468	outer membrane autotransporter barrel domain protein
XppCFBP6546P_08600	COG0784	Response regulator, receiver
XppCFBP6546P_08600	COG2205	protein histidine kinase activity
XppCFBP6546P_08615	COG5002	protein histidine kinase activity
XppCFBP6546P_08615	COG3447	MASE1 domain protein
XppCFBP6546P_08615	COG5001	Diguanylate cyclase
XppCFBP6546P_08645	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
XppCFBP6546P_08660	COG0598	Magnesium transport protein CorA
XppCFBP6546P_08670	COG1113	amino acid transport
XppCFBP6546P_08680	COG5297	Belongs to the glycosyl hydrolase family 6
XppCFBP6546P_08685	COG4305	rare lipoprotein A
XppCFBP6546P_08690	COG0697	spore germination
XppCFBP6546P_08715	COG1959	2 iron, 2 sulfur cluster binding
XppCFBP6546P_08720	COG3706	GGDEF domain
XppCFBP6546P_08785	COG0435	Glutathione S-transferase
XppCFBP6546P_08795	COG4221	oxidoreductase activity
XppCFBP6546P_08825	COG4221	oxidoreductase activity
XppCFBP6546P_08835	COG3328	transposase activity
XppCFBP6546P_08840	COG3328	transposase activity
XppCFBP6546P_08890	COG1802	Transcriptional regulator
XppCFBP6546P_08900	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
XppCFBP6546P_08905	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
XppCFBP6546P_08925	COG3052	prosthetic group binding
XppCFBP6546P_08960	COG2353	YceI-like domain
XppCFBP6546P_08965	COG0778	Nitroreductase
XppCFBP6546P_08985	COG3039	Transposase
XppCFBP6546P_09005	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
XppCFBP6546P_09010	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
XppCFBP6546P_09035	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
XppCFBP6546P_09040	COG3550	peptidyl-serine autophosphorylation
XppCFBP6546P_09055	COG0459	protein refolding
XppCFBP6546P_09060	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
XppCFBP6546P_09075	COG1324	tolerance protein
XppCFBP6546P_09085	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
XppCFBP6546P_09090	COG0511	ligase activity, forming carbon-carbon bonds
XppCFBP6546P_09100	COG0439	Biotin carboxylase
XppCFBP6546P_09120	COG2264	protein methyltransferase activity
XppCFBP6546P_09145	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
XppCFBP6546P_09150	COG4589	Belongs to the CDS family
XppCFBP6546P_09175	COG2453	phosphatase
XppCFBP6546P_09175	COG0671	phosphoesterase, PA-phosphatase related
XppCFBP6546P_09180	COG2267	carboxylic ester hydrolase activity
XppCFBP6546P_09185	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
XppCFBP6546P_09190	COG0138	bifunctional purine biosynthesis protein purh
XppCFBP6546P_09200	COG0151	Belongs to the GarS family
XppCFBP6546P_09210	COG1289	transmembrane transporter activity
XppCFBP6546P_09215	COG2814	Major facilitator Superfamily
XppCFBP6546P_09225	COG2814	Major facilitator Superfamily
XppCFBP6546P_09240	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
XppCFBP6546P_09260	COG0316	Belongs to the HesB IscA family
XppCFBP6546P_09300	COG1051	belongs to the nudix hydrolase family
XppCFBP6546P_09315	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
XppCFBP6546P_09320	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
XppCFBP6546P_09325	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
XppCFBP6546P_09335	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
XppCFBP6546P_09340	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XppCFBP6546P_09350	COG0134	indole-3-glycerol-phosphate synthase activity
XppCFBP6546P_09355	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
XppCFBP6546P_09380	COG1597	lipid kinase activity
XppCFBP6546P_09400	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
XppCFBP6546P_09405	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
XppCFBP6546P_09425	COG3179	chitinase
XppCFBP6546P_09445	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
XppCFBP6546P_09445	COG2111	Na H antiporter
XppCFBP6546P_09450	COG1006	Multisubunit Na H antiporter MnhC subunit
XppCFBP6546P_09455	COG0651	ATP synthesis coupled electron transport
XppCFBP6546P_09465	COG2212	antiporter activity
XppCFBP6546P_09470	COG1320	monovalent cation:proton antiporter activity
XppCFBP6546P_09490	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
XppCFBP6546P_09495	COG2852	Protein conserved in bacteria
XppCFBP6546P_09520	COG3483	tryptophan 2,3-dioxygenase activity
XppCFBP6546P_09530	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
XppCFBP6546P_09545	COG0508	dehydrogenase complex catalyzes the overall conversion of
XppCFBP6546P_09550	COG0513	Belongs to the DEAD box helicase family
XppCFBP6546P_09560	COG1028	Short-chain dehydrogenase reductase Sdr
XppCFBP6546P_09565	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XppCFBP6546P_09605	COG3039	Transposase
XppCFBP6546P_09615	COG3328	transposase activity
XppCFBP6546P_09635	COG0702	epimerase
XppCFBP6546P_09660	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
XppCFBP6546P_09665	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
XppCFBP6546P_09670	COG0297	glycogen (starch) synthase activity
XppCFBP6546P_09675	COG3706	GGDEF domain
XppCFBP6546P_09675	COG0745	RESPONSE REGULATOR receiver
XppCFBP6546P_09680	COG2354	Protein conserved in bacteria
XppCFBP6546P_09685	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
XppCFBP6546P_09690	COG1368	sulfuric ester hydrolase activity
XppCFBP6546P_09695	COG3264	Mechanosensitive ion channel
XppCFBP6546P_09695	COG1511	domain protein
XppCFBP6546P_09770	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
XppCFBP6546P_09840	COG3039	Transposase
XppCFBP6546P_09865	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
XppCFBP6546P_09870	COG1040	competence protein
XppCFBP6546P_09875	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
XppCFBP6546P_09880	COG0156	8-amino-7-oxononanoate synthase activity
XppCFBP6546P_09890	COG2267	carboxylic ester hydrolase activity
XppCFBP6546P_09935	COG0445	tRNA wobble uridine modification
XppCFBP6546P_09955	COG1414	Transcriptional regulator
XppCFBP6546P_09965	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
XppCFBP6546P_09970	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XppCFBP6546P_09980	COG3485	protocatechuate 3,4-dioxygenase
XppCFBP6546P_09985	COG3485	protocatechuate 3,4-dioxygenase
XppCFBP6546P_10000	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
XppCFBP6546P_10025	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
XppCFBP6546P_10030	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
XppCFBP6546P_10085	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
XppCFBP6546P_10100	COG0129	dihydroxy-acid dehydratase activity
XppCFBP6546P_10145	COG3328	transposase activity
XppCFBP6546P_10160	COG1733	regulation of RNA biosynthetic process
XppCFBP6546P_10165	COG0702	epimerase
XppCFBP6546P_10190	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
XppCFBP6546P_10205	COG0583	DNA-binding transcription factor activity
XppCFBP6546P_10210	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
XppCFBP6546P_10235	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XppCFBP6546P_10240	COG2205	protein histidine kinase activity
XppCFBP6546P_10245	COG0745	RESPONSE REGULATOR receiver
XppCFBP6546P_10265	COG1902	pentaerythritol trinitrate reductase activity
XppCFBP6546P_10270	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
XppCFBP6546P_10285	COG2814	Major facilitator Superfamily
XppCFBP6546P_10290	COG0583	DNA-binding transcription factor activity
XppCFBP6546P_10305	COG0084	hydrolase, TatD family'
XppCFBP6546P_10330	COG2252	PERMEase
XppCFBP6546P_10370	COG0583	DNA-binding transcription factor activity
XppCFBP6546P_10380	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
XppCFBP6546P_10400	COG2072	flavoprotein involved in K transport
XppCFBP6546P_10405	COG2351	hydroxyisourate hydrolase activity
XppCFBP6546P_10410	COG4807	Protein conserved in bacteria
XppCFBP6546P_10425	COG1643	Atp-dependent helicase
XppCFBP6546P_10435	COG1187	pseudouridine synthase activity
XppCFBP6546P_10450	COG2130	NADP-dependent
XppCFBP6546P_10470	COG1764	response to oxidative stress
XppCFBP6546P_10475	COG1846	Transcriptional regulator
XppCFBP6546P_10480	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
XppCFBP6546P_10490	COG0697	spore germination
XppCFBP6546P_10560	COG1960	acyl-CoA dehydrogenase activity
XppCFBP6546P_10565	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
XppCFBP6546P_10590	COG3039	Transposase
XppCFBP6546P_10605	COG3706	GGDEF domain
XppCFBP6546P_10610	COG2224	Isocitrate lyase
XppCFBP6546P_10625	COG0475	glutathione-regulated potassium exporter activity
XppCFBP6546P_10660	COG0339	signal peptide processing
XppCFBP6546P_10665	COG1446	asparaginase
XppCFBP6546P_10685	COG0564	pseudouridine synthase activity
XppCFBP6546P_10695	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
XppCFBP6546P_10710	COG1181	Belongs to the D-alanine--D-alanine ligase family
XppCFBP6546P_10725	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XppCFBP6546P_10730	COG0318	PFAM AMP-dependent synthetase and ligase
XppCFBP6546P_10740	COG0596	Alpha beta hydrolase
XppCFBP6546P_10745	COG3177	Filamentation induced by cAMP protein fic
XppCFBP6546P_10750	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XppCFBP6546P_10765	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
XppCFBP6546P_10790	COG2205	protein histidine kinase activity
XppCFBP6546P_10815	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
XppCFBP6546P_10820	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
XppCFBP6546P_10825	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
XppCFBP6546P_10865	COG0183	Belongs to the thiolase family
XppCFBP6546P_10880	COG2032	superoxide dismutase activity
XppCFBP6546P_10885	COG2032	superoxide dismutase activity
XppCFBP6546P_10890	COG2204	response regulator
XppCFBP6546P_10895	COG3852	Histidine kinase
XppCFBP6546P_10900	COG0004	ammonium transporteR
XppCFBP6546P_10905	COG0347	Belongs to the P(II) protein family
XppCFBP6546P_10910	COG0174	glutamine synthetase
XppCFBP6546P_10920	COG1968	undecaprenyl-diphosphatase activity
XppCFBP6546P_10970	COG2062	phosphohistidine phosphatase, SixA
XppCFBP6546P_10975	COG0489	protein tyrosine kinase activity
XppCFBP6546P_11005	COG1262	PFAM Formylglycine-generating sulfatase enzyme
XppCFBP6546P_11020	COG0517	IMP dehydrogenase activity
XppCFBP6546P_11020	COG1125	glycine betaine transport
XppCFBP6546P_11035	COG1119	ATPase activity
XppCFBP6546P_11045	COG1752	Esterase of the alpha-beta hydrolase superfamily
XppCFBP6546P_11055	COG1522	sequence-specific DNA binding
XppCFBP6546P_11060	COG3186	Phenylalanine-4-hydroxylase
XppCFBP6546P_11070	COG2755	lipolytic protein G-D-S-L family
XppCFBP6546P_11080	COG1028	Short-chain dehydrogenase reductase Sdr
XppCFBP6546P_11085	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
XppCFBP6546P_11095	COG1609	Transcriptional regulator
XppCFBP6546P_11100	COG3507	Belongs to the glycosyl hydrolase 43 family
XppCFBP6546P_11115	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
XppCFBP6546P_11125	COG2755	lipolytic protein G-D-S-L family
XppCFBP6546P_11125	COG0657	acetylesterase activity
XppCFBP6546P_11145	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
XppCFBP6546P_11150	COG0366	Alpha amylase catalytic
XppCFBP6546P_11170	COG3039	Transposase
XppCFBP6546P_11175	COG3039	Transposase
XppCFBP6546P_11220	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
XppCFBP6546P_11245	COG2197	response regulator
XppCFBP6546P_11250	COG4585	Histidine kinase
XppCFBP6546P_11255	COG1755	Isoprenylcysteine carboxyl methyltransferase
XppCFBP6546P_11260	COG1304	FMN binding
XppCFBP6546P_11290	COG4772	TonB-dependent receptor
XppCFBP6546P_11345	COG0714	Associated with various cellular activities
XppCFBP6546P_11390	COG0477	Major facilitator Superfamily
XppCFBP6546P_11400	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XppCFBP6546P_11445	COG3237	CsbD-like
XppCFBP6546P_11455	COG3039	Transposase
XppCFBP6546P_11470	COG3039	Transposase
XppCFBP6546P_11480	COG2249	NAD(P)H dehydrogenase (quinone) activity
XppCFBP6546P_11510	COG1028	Short-chain dehydrogenase reductase Sdr
XppCFBP6546P_11515	COG0300	oxidoreductase activity
XppCFBP6546P_11535	COG1272	protein, Hemolysin III
XppCFBP6546P_11540	COG1111	helicase
XppCFBP6546P_11540	COG1205	dead DEAH box helicase
XppCFBP6546P_11635	COG0067	glutamate synthase
XppCFBP6546P_11635	COG0069	glutamate synthase activity
XppCFBP6546P_11635	COG0070	glutamate synthase
XppCFBP6546P_11640	COG0493	'glutamate synthase
XppCFBP6546P_11655	COG1064	alcohol dehydrogenase
XppCFBP6546P_11665	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XppCFBP6546P_11675	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XppCFBP6546P_11680	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XppCFBP6546P_11690	COG2234	aminopeptidase activity
XppCFBP6546P_11700	COG4942	peptidase
XppCFBP6546P_11705	COG0793	Belongs to the peptidase S41A family
XppCFBP6546P_11760	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
XppCFBP6546P_11805	COG0501	Belongs to the peptidase M48B family
XppCFBP6546P_11815	COG0187	DNA topoisomerase II activity
XppCFBP6546P_11820	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
XppCFBP6546P_11840	COG0230	Belongs to the bacterial ribosomal protein bL34 family
XppCFBP6546P_11845	COG0594	ribonuclease P activity
XppCFBP6546P_11850	COG0706	membrane insertase activity
XppCFBP6546P_11860	COG0726	polysaccharide deacetylase
XppCFBP6546P_11865	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
XppCFBP6546P_11880	COG0584	glycerophosphoryl diester phosphodiesterase
XppCFBP6546P_11905	COG0861	Integral membrane protein TerC family
XppCFBP6546P_11915	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
XppCFBP6546P_11930	COG2271	Major facilitator Superfamily
XppCFBP6546P_11935	COG1929	Belongs to the glycerate kinase type-1 family
XppCFBP6546P_11940	COG3835	regulator
XppCFBP6546P_11945	COG2199	diguanylate cyclase activity
XppCFBP6546P_11945	COG2203	Gaf domain
XppCFBP6546P_11960	COG3537	Alpha-1,2-mannosidase
XppCFBP6546P_11965	COG0531	amino acid
XppCFBP6546P_11985	COG0583	DNA-binding transcription factor activity
XppCFBP6546P_11995	COG1322	Protein conserved in bacteria
XppCFBP6546P_12005	COG0386	Belongs to the glutathione peroxidase family
XppCFBP6546P_12015	COG2853	Lipoprotein
XppCFBP6546P_12030	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
XppCFBP6546P_12035	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
XppCFBP6546P_12040	COG1127	ABC transporter
XppCFBP6546P_12075	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
XppCFBP6546P_12080	COG1074	ATP-dependent DNA helicase activity
XppCFBP6546P_12145	COG1028	Short-chain dehydrogenase reductase Sdr
XppCFBP6546P_12175	COG0439	Biotin carboxylase
XppCFBP6546P_12275	COG3039	Transposase
XppCFBP6546P_12410	COG4789	Type iii secretion
XppCFBP6546P_12420	COG1157	protein secretion by the type III secretion system
XppCFBP6546P_12540	COG0564	pseudouridine synthase activity
XppCFBP6546P_12565	COG3328	transposase activity
XppCFBP6546P_12590	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XppCFBP6546P_12595	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XppCFBP6546P_12605	COG4221	oxidoreductase activity
XppCFBP6546P_12610	COG0583	DNA-binding transcription factor activity
XppCFBP6546P_12620	COG0477	Major facilitator Superfamily
XppCFBP6546P_12625	COG1289	transmembrane transporter activity
XppCFBP6546P_12635	COG1566	PFAM secretion protein HlyD family protein
XppCFBP6546P_12650	COG0302	gtp cyclohydrolase
XppCFBP6546P_12665	COG3328	transposase activity
XppCFBP6546P_12675	COG0730	response to heat
XppCFBP6546P_12690	COG3328	transposase activity
XppCFBP6546P_12725	COG3012	SEC-C Motif Domain Protein
XppCFBP6546P_12735	COG0676	glucose-6-phosphate 1-epimerase activity
XppCFBP6546P_12795	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
XppCFBP6546P_12805	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
XppCFBP6546P_12815	COG1435	thymidine kinase activity
XppCFBP6546P_12820	COG0210	DNA helicase
XppCFBP6546P_12870	COG0635	Involved in the biosynthesis of porphyrin-containing compound
XppCFBP6546P_12880	COG3132	Protein of unknown function, DUF480
XppCFBP6546P_12885	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
XppCFBP6546P_12890	COG0284	orotidine-5'-phosphate decarboxylase activity
XppCFBP6546P_12925	COG2937	Belongs to the GPAT DAPAT family
XppCFBP6546P_12970	COG3328	transposase activity
XppCFBP6546P_13000	COG3039	Transposase
XppCFBP6546P_13045	COG2211	Major facilitator Superfamily
XppCFBP6546P_13060	COG3693	PFAM glycoside hydrolase, family 10
XppCFBP6546P_13070	COG3693	PFAM glycoside hydrolase, family 10
XppCFBP6546P_13075	COG1904	glucuronate isomerase
XppCFBP6546P_13090	COG3386	PFAM SMP-30 Gluconolaconase
XppCFBP6546P_13115	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
XppCFBP6546P_13180	COG0246	Mannitol dehydrogenase
XppCFBP6546P_13185	COG1472	Belongs to the glycosyl hydrolase 3 family
XppCFBP6546P_13195	COG4948	Mandelate Racemase Muconate Lactonizing
XppCFBP6546P_13205	COG3661	Belongs to the glycosyl hydrolase 67 family
XppCFBP6546P_13215	COG2115	Belongs to the xylose isomerase family
XppCFBP6546P_13225	COG0037	tRNA processing
XppCFBP6546P_13230	COG2974	May be involved in recombination
XppCFBP6546P_13250	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
XppCFBP6546P_13260	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
XppCFBP6546P_13270	COG0805	protein transport
XppCFBP6546P_13285	COG0518	GMP synthase (glutamine-hydrolyzing) activity
XppCFBP6546P_13285	COG0519	Catalyzes the synthesis of GMP from XMP
XppCFBP6546P_13300	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
XppCFBP6546P_13305	COG0752	glycyl-tRNA synthetase alpha subunit
XppCFBP6546P_13315	COG0457	Tetratricopeptide repeat
XppCFBP6546P_13325	COG4771	TonB-dependent receptor
XppCFBP6546P_13330	COG0729	surface antigen
XppCFBP6546P_13335	COG2911	Protein conserved in bacteria
XppCFBP6546P_13340	COG3328	transposase activity
XppCFBP6546P_13360	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XppCFBP6546P_13370	COG3265	gluconokinase activity
XppCFBP6546P_13375	COG2211	Major facilitator Superfamily
XppCFBP6546P_13380	COG3459	Glycosyltransferase 36 associated
XppCFBP6546P_13395	COG2205	protein histidine kinase activity
XppCFBP6546P_13400	COG1971	Probably functions as a manganese efflux pump
XppCFBP6546P_13410	COG1917	Cupin 2, conserved barrel domain protein
XppCFBP6546P_13410	COG2207	Transcriptional regulator
XppCFBP6546P_13415	COG1414	Transcriptional regulator
XppCFBP6546P_13420	COG0738	Major facilitator superfamily
XppCFBP6546P_13425	COG3254	rhamnose metabolic process
XppCFBP6546P_13430	COG4948	Mandelate Racemase Muconate Lactonizing
XppCFBP6546P_13435	COG0179	Fumarylacetoacetate (FAA) hydrolase
XppCFBP6546P_13440	COG1028	Short-chain dehydrogenase reductase Sdr
XppCFBP6546P_13460	COG3507	Belongs to the glycosyl hydrolase 43 family
XppCFBP6546P_13490	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
XppCFBP6546P_13500	COG3162	membrane
XppCFBP6546P_13525	COG1846	Transcriptional regulator
XppCFBP6546P_13525	COG1940	carbohydrate kinase activity
XppCFBP6546P_13530	COG0708	Exodeoxyribonuclease III
XppCFBP6546P_13545	COG2091	lysine biosynthetic process via aminoadipic acid
XppCFBP6546P_13555	COG3540	Alkaline phosphatase
XppCFBP6546P_13560	COG0357	Ribosomal RNA small subunit methyltransferase G
XppCFBP6546P_13585	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XppCFBP6546P_13605	COG0227	Belongs to the bacterial ribosomal protein bL28 family
XppCFBP6546P_13610	COG0267	Belongs to the bacterial ribosomal protein bL33 family
XppCFBP6546P_13615	COG2159	amidohydrolase
XppCFBP6546P_13630	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
XppCFBP6546P_13635	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XppCFBP6546P_13735	COG3328	transposase activity
XppCFBP6546P_13760	COG0154	amidase activity
XppCFBP6546P_13820	COG3501	Rhs element vgr protein
XppCFBP6546P_13835	COG0583	DNA-binding transcription factor activity
XppCFBP6546P_13840	COG0667	Aldo Keto reductase
XppCFBP6546P_13865	COG0631	protein serine/threonine phosphatase activity
XppCFBP6546P_13870	COG0515	serine threonine protein kinase
XppCFBP6546P_13955	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
XppCFBP6546P_13970	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
XppCFBP6546P_14010	COG1028	Short-chain dehydrogenase reductase Sdr
XppCFBP6546P_14020	COG0463	Glycosyl transferase, family 2
XppCFBP6546P_14030	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
XppCFBP6546P_14035	COG3100	YcgL domain-containing protein
XppCFBP6546P_14050	COG3387	PFAM Glycoside hydrolase 15-related
XppCFBP6546P_14055	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
XppCFBP6546P_14085	COG2239	Acts as a magnesium transporter
XppCFBP6546P_14090	COG0045	succinate-CoA ligase (ADP-forming) activity
XppCFBP6546P_14090	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
XppCFBP6546P_14090	COG1042	CoA-binding domain protein
XppCFBP6546P_14105	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
XppCFBP6546P_14110	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
XppCFBP6546P_14130	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XppCFBP6546P_14160	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
XppCFBP6546P_14165	COG0842	Transport permease protein
XppCFBP6546P_14170	COG1131	(ABC) transporter
XppCFBP6546P_14175	COG0633	Ferredoxin
XppCFBP6546P_14175	COG0543	2 iron, 2 sulfur cluster binding
XppCFBP6546P_14180	COG1230	cation diffusion facilitator family transporter
XppCFBP6546P_14200	COG1476	TRANSCRIPTIONal
XppCFBP6546P_14210	COG4555	ABC transporter
XppCFBP6546P_14300	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
XppCFBP6546P_14315	COG1199	ATP-dependent helicase activity
XppCFBP6546P_14330	COG3328	transposase activity
XppCFBP6546P_14370	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
XppCFBP6546P_14380	COG0745	RESPONSE REGULATOR receiver
XppCFBP6546P_14385	COG2205	protein histidine kinase activity
XppCFBP6546P_14400	COG3228	Belongs to the MtfA family
XppCFBP6546P_14415	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
XppCFBP6546P_14415	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
XppCFBP6546P_14420	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
XppCFBP6546P_14435	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
XppCFBP6546P_14480	COG3237	CsbD-like
XppCFBP6546P_14485	COG0180	Tryptophanyl-tRNA synthetase
XppCFBP6546P_14490	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XppCFBP6546P_14495	COG3328	transposase activity
XppCFBP6546P_14520	COG0697	spore germination
XppCFBP6546P_14545	COG1136	(ABC) transporter
XppCFBP6546P_14550	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XppCFBP6546P_14555	COG4585	Histidine kinase
XppCFBP6546P_14560	COG2197	response regulator
XppCFBP6546P_14580	COG0753	catalase activity
XppCFBP6546P_14595	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
XppCFBP6546P_14600	COG1011	Hydrolase
XppCFBP6546P_14645	COG0642	Histidine kinase
XppCFBP6546P_14650	COG0745	RESPONSE REGULATOR receiver
XppCFBP6546P_14655	COG1090	epimerase
XppCFBP6546P_14695	COG1690	Belongs to the RtcB family
XppCFBP6546P_14730	COG4943	cyclic-guanylate-specific phosphodiesterase activity
XppCFBP6546P_14740	COG0606	chelatase, subunit chli
XppCFBP6546P_14760	COG3525	Glycosyl hydrolase, family 20, catalytic domain
XppCFBP6546P_14760	COG3291	Pkd domain containing protein
XppCFBP6546P_14780	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
XppCFBP6546P_14785	COG1166	arginine decarboxylase activity
XppCFBP6546P_14790	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
XppCFBP6546P_14800	COG2755	lipolytic protein G-D-S-L family
XppCFBP6546P_14800	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
XppCFBP6546P_14805	COG4221	oxidoreductase activity
XppCFBP6546P_14820	COG0018	arginyl-trna synthetase
XppCFBP6546P_14825	COG2003	Belongs to the UPF0758 family
XppCFBP6546P_14830	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
XppCFBP6546P_14835	COG0756	dUTP diphosphatase activity
XppCFBP6546P_14855	COG0463	Glycosyl transferase, family 2
XppCFBP6546P_14870	COG1475	DNA binding
XppCFBP6546P_14875	COG1192	Involved in chromosome partitioning
XppCFBP6546P_14890	COG0708	Exodeoxyribonuclease III
XppCFBP6546P_14895	COG2223	nitrite transmembrane transporter activity
XppCFBP6546P_14905	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
XppCFBP6546P_14915	COG0739	heme binding
XppCFBP6546P_14920	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
XppCFBP6546P_14960	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
XppCFBP6546P_14970	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
XppCFBP6546P_15000	COG0109	protoheme IX farnesyltransferase activity
XppCFBP6546P_15015	COG0358	DNA primase activity
XppCFBP6546P_15020	COG1295	ribonuclease BN
XppCFBP6546P_15030	COG1610	YqeY-like protein
XppCFBP6546P_15035	COG0828	Belongs to the bacterial ribosomal protein bS21 family
XppCFBP6546P_15040	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
XppCFBP6546P_15045	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
XppCFBP6546P_15055	COG2133	pyrroloquinoline quinone binding
XppCFBP6546P_15060	COG4682	membrane
XppCFBP6546P_15065	COG3328	transposase activity
XppCFBP6546P_15085	COG0531	amino acid
XppCFBP6546P_15105	COG3023	N-Acetylmuramoyl-L-alanine amidase
XppCFBP6546P_15110	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
XppCFBP6546P_15150	COG5383	Protein conserved in bacteria
XppCFBP6546P_15170	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XppCFBP6546P_15175	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XppCFBP6546P_15180	COG1473	amidohydrolase
XppCFBP6546P_15185	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
XppCFBP6546P_15185	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
XppCFBP6546P_15190	COG1652	LysM domain
XppCFBP6546P_15215	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
XppCFBP6546P_15225	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
XppCFBP6546P_15230	COG3118	belongs to the thioredoxin family
XppCFBP6546P_15235	COG0513	Belongs to the DEAD box helicase family
XppCFBP6546P_15240	COG2884	Cell division ATP-binding protein ftsE
XppCFBP6546P_15245	COG2177	Part of the ABC transporter FtsEX involved in
XppCFBP6546P_15250	COG2201	protein-glutamate methylesterase activity
XppCFBP6546P_15255	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
XppCFBP6546P_15260	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
XppCFBP6546P_15265	COG2860	membrane
XppCFBP6546P_15285	COG0625	glutathione transferase activity
XppCFBP6546P_15290	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
XppCFBP6546P_15310	COG0534	Mate efflux family protein
XppCFBP6546P_15315	COG0616	signal peptide processing
XppCFBP6546P_15330	COG1028	Short-chain dehydrogenase reductase Sdr
XppCFBP6546P_15345	COG0009	L-threonylcarbamoyladenylate synthase
XppCFBP6546P_15350	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
XppCFBP6546P_15350	COG1754	DNA topoisomerase type I activity
XppCFBP6546P_15370	COG0758	DNA mediated transformation
XppCFBP6546P_15375	COG1652	LysM domain
XppCFBP6546P_15380	COG0242	peptide deformylase activity
XppCFBP6546P_15385	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
XppCFBP6546P_15390	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
XppCFBP6546P_15390	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
XppCFBP6546P_15435	COG1560	Kdo2-lipid A biosynthetic process
XppCFBP6546P_15440	COG1490	D-aminoacyl-tRNA deacylase activity
XppCFBP6546P_15445	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
XppCFBP6546P_15480	COG0024	Methionine aminopeptidase
XppCFBP6546P_15490	COG0038	chloride channel
XppCFBP6546P_15520	COG0251	oxidation-reduction process
XppCFBP6546P_15590	COG3328	transposase activity
XppCFBP6546P_15600	COG1063	alcohol dehydrogenase
XppCFBP6546P_15620	COG1028	Short-chain dehydrogenase reductase Sdr
XppCFBP6546P_15635	COG1294	oxidase, subunit
XppCFBP6546P_15640	COG1271	oxidase subunit
XppCFBP6546P_15690	COG3546	catalase activity
XppCFBP6546P_15695	COG3685	Protein conserved in bacteria
XppCFBP6546P_15715	COG2972	Histidine kinase
XppCFBP6546P_15730	COG0531	amino acid
XppCFBP6546P_15760	COG0667	Aldo Keto reductase
XppCFBP6546P_15770	COG0583	DNA-binding transcription factor activity
XppCFBP6546P_15780	COG3384	dioxygenase
XppCFBP6546P_15790	COG1573	uracil-dna glycosylase
XppCFBP6546P_15795	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
XppCFBP6546P_15805	COG0025	NhaP-type Na H and K H
XppCFBP6546P_15810	COG1131	(ABC) transporter
XppCFBP6546P_15815	COG0842	Transport permease protein
XppCFBP6546P_15865	COG1522	sequence-specific DNA binding
XppCFBP6546P_15875	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
XppCFBP6546P_15895	COG2205	protein histidine kinase activity
XppCFBP6546P_15895	COG2202	Pas domain
XppCFBP6546P_15910	COG3328	transposase activity
XppCFBP6546P_15915	COG3039	Transposase
XppCFBP6546P_15935	COG1187	pseudouridine synthase activity
XppCFBP6546P_15940	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
XppCFBP6546P_15965	COG0784	Response regulator, receiver
XppCFBP6546P_15965	COG2198	Histidine kinase
XppCFBP6546P_15965	COG5002	protein histidine kinase activity
XppCFBP6546P_15975	COG1666	GTP binding
XppCFBP6546P_15980	COG0697	spore germination
XppCFBP6546P_15985	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
XppCFBP6546P_15990	COG2011	ABC-type metal ion transport system permease component
XppCFBP6546P_16030	COG0508	dehydrogenase complex catalyzes the overall conversion of
XppCFBP6546P_16040	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XppCFBP6546P_16060	COG0356	it plays a direct role in the translocation of protons across the membrane
XppCFBP6546P_16070	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
XppCFBP6546P_16075	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
XppCFBP6546P_16080	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
XppCFBP6546P_16085	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
XppCFBP6546P_16090	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
XppCFBP6546P_16095	COG0355	proton-transporting ATP synthase activity, rotational mechanism
XppCFBP6546P_16110	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
XppCFBP6546P_16115	COG4191	Histidine kinase
XppCFBP6546P_16120	COG2204	response regulator
XppCFBP6546P_16135	COG0577	efflux transmembrane transporter activity
XppCFBP6546P_16135	COG1136	(ABC) transporter
XppCFBP6546P_16140	COG1136	(ABC) transporter
XppCFBP6546P_16145	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XppCFBP6546P_16150	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
XppCFBP6546P_16185	COG2132	Multicopper oxidase
XppCFBP6546P_16200	COG0339	signal peptide processing
XppCFBP6546P_16210	COG4991	sh3 domain protein
XppCFBP6546P_16220	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
XppCFBP6546P_16225	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
XppCFBP6546P_16240	COG1956	GAF domain-containing protein
XppCFBP6546P_16250	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
XppCFBP6546P_16260	COG0720	synthase
XppCFBP6546P_16265	COG0513	Belongs to the DEAD box helicase family
XppCFBP6546P_16280	COG0625	glutathione transferase activity
XppCFBP6546P_16310	COG0626	cystathionine gamma-synthase activity
XppCFBP6546P_16320	COG0438	transferase activity, transferring glycosyl groups
XppCFBP6546P_16340	COG0438	transferase activity, transferring glycosyl groups
XppCFBP6546P_16345	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
XppCFBP6546P_16375	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XppCFBP6546P_16385	COG0277	FAD linked oxidase domain protein
XppCFBP6546P_16390	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
XppCFBP6546P_16390	COG0546	phosphoglycolate phosphatase activity
XppCFBP6546P_16405	COG2086	electron transfer activity
XppCFBP6546P_16440	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
XppCFBP6546P_16470	COG3218	ABC-type transport auxiliary lipoprotein component
XppCFBP6546P_16470	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
XppCFBP6546P_16475	COG1127	ABC transporter
XppCFBP6546P_16480	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
XppCFBP6546P_16495	COG0442	prolyl-tRNA aminoacylation
XppCFBP6546P_16505	COG1183	phosphatidylcholine synthase activity
XppCFBP6546P_16525	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
XppCFBP6546P_16530	COG1012	belongs to the aldehyde dehydrogenase family
XppCFBP6546P_16535	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
XppCFBP6546P_16545	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
XppCFBP6546P_16575	COG2205	protein histidine kinase activity
XppCFBP6546P_16580	COG0745	RESPONSE REGULATOR receiver
XppCFBP6546P_16605	COG3791	Glutathione-dependent formaldehyde-activating
XppCFBP6546P_16610	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
XppCFBP6546P_16630	COG1307	EDD domain protein, DegV family
XppCFBP6546P_16670	COG0402	S-adenosylhomocysteine deaminase activity
XppCFBP6546P_16675	COG3964	amidohydrolase
XppCFBP6546P_16690	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
XppCFBP6546P_16695	COG0726	polysaccharide deacetylase
XppCFBP6546P_16710	COG0436	Aminotransferase
XppCFBP6546P_16715	COG1162	GTPase activity
XppCFBP6546P_16740	COG2211	Major facilitator Superfamily
XppCFBP6546P_16745	COG1609	Transcriptional regulator
XppCFBP6546P_16750	COG1028	Short-chain dehydrogenase reductase Sdr
XppCFBP6546P_16755	COG2851	Citrate transporter
XppCFBP6546P_16775	COG0642	Histidine kinase
XppCFBP6546P_16780	COG1840	ABC-type Fe3 transport system, periplasmic component
XppCFBP6546P_16790	COG2197	response regulator
XppCFBP6546P_16805	COG0667	Aldo Keto reductase
XppCFBP6546P_16810	COG0583	DNA-binding transcription factor activity
XppCFBP6546P_16835	COG1301	dicarboxylic acid transport
XppCFBP6546P_16840	COG0280	phosphate acetyltransferase
XppCFBP6546P_16840	COG0281	malic enzyme
XppCFBP6546P_16865	COG1560	Kdo2-lipid A biosynthetic process
XppCFBP6546P_16870	COG1519	Transferase
XppCFBP6546P_16875	COG1538	Outer membrane efflux protein
XppCFBP6546P_16880	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
XppCFBP6546P_16900	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
XppCFBP6546P_16905	COG0066	3-isopropylmalate dehydratase activity
XppCFBP6546P_16910	COG0473	3-isopropylmalate dehydrogenase activity
XppCFBP6546P_16915	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
XppCFBP6546P_16935	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
XppCFBP6546P_16940	COG0405	Gamma-glutamyltransferase
XppCFBP6546P_16945	COG0840	transmembrane signaling receptor activity
XppCFBP6546P_16960	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
XppCFBP6546P_16965	COG3710	Transcriptional regulator
XppCFBP6546P_16985	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
XppCFBP6546P_16995	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
XppCFBP6546P_17010	COG0563	adenylate kinase activity
XppCFBP6546P_17015	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
XppCFBP6546P_17025	COG3781	membrane
XppCFBP6546P_17035	COG0671	phosphoesterase, PA-phosphatase related
XppCFBP6546P_17045	COG1028	Short-chain dehydrogenase reductase Sdr
XppCFBP6546P_17050	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XppCFBP6546P_17055	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
XppCFBP6546P_17085	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XppCFBP6546P_17090	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
XppCFBP6546P_17100	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
XppCFBP6546P_17130	COG0352	thiamine-phosphate diphosphorylase activity
XppCFBP6546P_17135	COG1773	rubredoxin
XppCFBP6546P_17145	COG2912	Transglutaminase-like superfamily
XppCFBP6546P_17165	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
XppCFBP6546P_17185	COG3079	Belongs to the UPF0149 family
XppCFBP6546P_17190	COG0006	proline dipeptidase activity
XppCFBP6546P_17200	COG0006	proline dipeptidase activity
XppCFBP6546P_17215	COG0635	Involved in the biosynthesis of porphyrin-containing compound
XppCFBP6546P_17220	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
XppCFBP6546P_17230	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
XppCFBP6546P_17235	COG1561	YicC-like family, N-terminal region
XppCFBP6546P_17245	COG1758	RNA polymerase activity
XppCFBP6546P_17250	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
XppCFBP6546P_17260	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
XppCFBP6546P_17265	COG1957	nucleoside hydrolase
XppCFBP6546P_17270	COG0254	rRNA binding
XppCFBP6546P_17285	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
XppCFBP6546P_17335	COG2304	oxidoreductase activity
XppCFBP6546P_17345	COG1301	dicarboxylic acid transport
XppCFBP6546P_17350	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
XppCFBP6546P_17365	COG4773	Receptor
XppCFBP6546P_17370	COG0739	heme binding
XppCFBP6546P_17375	COG1376	ErfK ybiS ycfS ynhG family protein
XppCFBP6546P_17400	COG1022	Amp-dependent synthetase and ligase
XppCFBP6546P_17420	COG0745	RESPONSE REGULATOR receiver
XppCFBP6546P_17425	COG0642	Histidine kinase
XppCFBP6546P_17445	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
XppCFBP6546P_17450	COG4149	molybdate abc transporter
XppCFBP6546P_17455	COG0725	ABC transporter, periplasmic molybdate-binding protein
XppCFBP6546P_17460	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XppCFBP6546P_17460	COG3453	Protein conserved in bacteria
XppCFBP6546P_17475	COG3047	cAMP biosynthetic process
XppCFBP6546P_17485	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
XppCFBP6546P_17520	COG0126	phosphoglycerate kinase activity
XppCFBP6546P_17530	COG0469	pyruvate kinase activity
XppCFBP6546P_17540	COG3588	fructose-bisphosphate aldolase
XppCFBP6546P_17545	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
XppCFBP6546P_17560	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
XppCFBP6546P_17560	COG1648	precorrin-2 dehydrogenase activity
XppCFBP6546P_17600	COG0175	sulfate reduction
XppCFBP6546P_17605	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
XppCFBP6546P_17610	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
XppCFBP6546P_17615	COG0175	sulfate reduction
XppCFBP6546P_17620	COG0529	Catalyzes the synthesis of activated sulfate
XppCFBP6546P_17620	COG2895	sulfate adenylyltransferase (ATP) activity
XppCFBP6546P_17630	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XppCFBP6546P_17635	COG0308	aminopeptidase N
XppCFBP6546P_17645	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
XppCFBP6546P_17655	COG4948	Mandelate Racemase Muconate Lactonizing
XppCFBP6546P_17660	COG3250	beta-galactosidase activity
XppCFBP6546P_17670	COG1609	Transcriptional regulator
XppCFBP6546P_17680	COG1970	mechanosensitive ion channel activity
XppCFBP6546P_17705	COG3273	potassium ion transport
XppCFBP6546P_17705	COG0471	metal ion transport
XppCFBP6546P_17710	COG0220	tRNA (guanine-N7-)-methyltransferase activity
XppCFBP6546P_17720	COG2022	thiamine diphosphate biosynthetic process
XppCFBP6546P_17760	COG3328	transposase activity
XppCFBP6546P_17785	COG2003	Belongs to the UPF0758 family
XppCFBP6546P_17810	COG3328	transposase activity
XppCFBP6546P_17830	COG0189	ligase activity
XppCFBP6546P_17840	COG0745	RESPONSE REGULATOR receiver
XppCFBP6546P_17880	COG3328	transposase activity
XppCFBP6546P_17920	COG0045	succinate-CoA ligase (ADP-forming) activity
XppCFBP6546P_17925	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
XppCFBP6546P_17940	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XppCFBP6546P_17940	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
XppCFBP6546P_17950	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XppCFBP6546P_17955	COG0564	pseudouridine synthase activity
XppCFBP6546P_17970	COG3011	Protein conserved in bacteria
XppCFBP6546P_17975	COG0840	transmembrane signaling receptor activity
XppCFBP6546P_17985	COG3328	transposase activity
XppCFBP6546P_18010	COG3387	PFAM Glycoside hydrolase 15-related
XppCFBP6546P_18015	COG1877	trehalose-phosphatase activity
XppCFBP6546P_18065	COG0542	response to heat
XppCFBP6546P_18075	COG4206	TonB-dependent receptor
XppCFBP6546P_18095	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
XppCFBP6546P_18105	COG1492	cobalamin metabolic process
XppCFBP6546P_18115	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
XppCFBP6546P_18140	COG0019	diaminopimelate decarboxylase activity
XppCFBP6546P_18155	COG4264	IucA IucC family
XppCFBP6546P_18165	COG4772	TonB-dependent receptor
XppCFBP6546P_18185	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
XppCFBP6546P_18195	COG1024	Enoyl-CoA hydratase
XppCFBP6546P_18205	COG0494	nUDIX hydrolase
XppCFBP6546P_18250	COG0116	Belongs to the methyltransferase superfamily
XppCFBP6546P_18250	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
XppCFBP6546P_18255	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
XppCFBP6546P_18275	COG2925	Exonuclease
XppCFBP6546P_18285	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XppCFBP6546P_18290	COG3844	kynureninase activity
XppCFBP6546P_18300	COG0662	Cupin 2, conserved barrel domain protein
XppCFBP6546P_18305	COG0288	reversible hydration of carbon dioxide
XppCFBP6546P_18385	COG0017	Asparaginyl-tRNA synthetase
XppCFBP6546P_18395	COG0316	Belongs to the HesB IscA family
XppCFBP6546P_18400	COG0360	Binds together with S18 to 16S ribosomal RNA
XppCFBP6546P_18405	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
XppCFBP6546P_18410	COG0359	binds to the 23S rRNA
XppCFBP6546P_18420	COG3115	cell septum assembly
XppCFBP6546P_18430	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XppCFBP6546P_18435	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
XppCFBP6546P_18440	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
XppCFBP6546P_18455	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
XppCFBP6546P_18465	COG4993	Dehydrogenase
XppCFBP6546P_18475	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
XppCFBP6546P_18490	COG2986	histidine ammonia-lyase
XppCFBP6546P_18495	COG1228	amidohydrolase
XppCFBP6546P_18535	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
XppCFBP6546P_18545	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
XppCFBP6546P_18550	COG0077	Prephenate dehydratase
XppCFBP6546P_18550	COG1605	Chorismate mutase
XppCFBP6546P_18555	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
XppCFBP6546P_18570	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
XppCFBP6546P_18575	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
XppCFBP6546P_18580	COG0583	DNA-binding transcription factor activity
XppCFBP6546P_18600	COG0840	transmembrane signaling receptor activity
XppCFBP6546P_18620	COG0784	Response regulator, receiver
XppCFBP6546P_18620	COG4191	Histidine kinase
XppCFBP6546P_18630	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
XppCFBP6546P_18650	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XppCFBP6546P_18660	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
XppCFBP6546P_18670	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
XppCFBP6546P_18685	COG1595	DNA-templated transcription, initiation
XppCFBP6546P_18740	COG2244	polysaccharide biosynthetic process
XppCFBP6546P_18770	COG2264	protein methyltransferase activity
XppCFBP6546P_18795	COG1136	(ABC) transporter
XppCFBP6546P_18805	COG0477	Major facilitator Superfamily
XppCFBP6546P_18810	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XppCFBP6546P_18825	COG1253	flavin adenine dinucleotide binding
XppCFBP6546P_18840	COG0306	phosphate transporter
XppCFBP6546P_18865	COG0504	CTP synthase activity
XppCFBP6546P_18870	COG2877	3-deoxy-8-phosphooctulonate synthase activity
XppCFBP6546P_18880	COG0148	phosphopyruvate hydratase activity
XppCFBP6546P_18895	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
XppCFBP6546P_18900	COG0585	pseudouridine synthase activity
XppCFBP6546P_18905	COG2840	Smr protein MutS2
XppCFBP6546P_18910	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
XppCFBP6546P_18920	COG1238	metal cluster binding
XppCFBP6546P_18930	COG3737	Protein of unknown function (DUF498/DUF598)
XppCFBP6546P_18935	COG1534	Rna-binding protein
XppCFBP6546P_18940	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
XppCFBP6546P_18945	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
XppCFBP6546P_18950	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
XppCFBP6546P_18955	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
XppCFBP6546P_18960	COG1923	regulation of RNA biosynthetic process
XppCFBP6546P_18965	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
XppCFBP6546P_18970	COG1546	Belongs to the CinA family
XppCFBP6546P_18980	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
XppCFBP6546P_18985	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
XppCFBP6546P_18995	COG2137	regulation of response to DNA damage stimulus
XppCFBP6546P_19000	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
XppCFBP6546P_19005	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
XppCFBP6546P_19030	COG0583	DNA-binding transcription factor activity
XppCFBP6546P_19055	COG0351	phosphomethylpyrimidine kinase
XppCFBP6546P_19070	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
XppCFBP6546P_19075	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
XppCFBP6546P_19090	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
XppCFBP6546P_19100	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
XppCFBP6546P_19105	COG3734	2-keto-3-deoxy-galactonokinase
XppCFBP6546P_19115	COG4948	Mandelate Racemase Muconate Lactonizing
XppCFBP6546P_19120	COG0800	Aldolase
XppCFBP6546P_19170	COG1501	Belongs to the glycosyl hydrolase 31 family
XppCFBP6546P_19180	COG1070	Carbohydrate kinase
XppCFBP6546P_19185	COG2115	Belongs to the xylose isomerase family
XppCFBP6546P_19190	COG0477	Major facilitator Superfamily
XppCFBP6546P_19210	COG0860	N-Acetylmuramoyl-L-alanine amidase
XppCFBP6546P_19215	COG1469	GTP cyclohydrolase I activity
XppCFBP6546P_19240	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
XppCFBP6546P_19245	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
XppCFBP6546P_19250	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
XppCFBP6546P_19255	COG0166	Belongs to the GPI family
XppCFBP6546P_19275	COG1472	Belongs to the glycosyl hydrolase 3 family
XppCFBP6546P_19290	COG2203	Gaf domain
XppCFBP6546P_19290	COG3706	GGDEF domain
XppCFBP6546P_19290	COG4251	negative regulation of phosphorylation
XppCFBP6546P_19290	COG5001	Diguanylate cyclase
XppCFBP6546P_19295	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XppCFBP6546P_19300	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
XppCFBP6546P_19310	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
XppCFBP6546P_19315	COG0671	phosphoesterase, PA-phosphatase related
XppCFBP6546P_19330	COG0697	spore germination
XppCFBP6546P_19335	COG0812	UDP-N-acetylmuramate dehydrogenase activity
XppCFBP6546P_19340	COG0167	dihydroorotate dehydrogenase activity
XppCFBP6546P_19360	COG1012	belongs to the aldehyde dehydrogenase family
XppCFBP6546P_19375	COG3328	transposase activity
XppCFBP6546P_19380	COG0366	Alpha amylase catalytic
XppCFBP6546P_19400	COG1082	Xylose isomerase domain protein TIM barrel
XppCFBP6546P_19410	COG2211	Major facilitator Superfamily
XppCFBP6546P_19425	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
XppCFBP6546P_19430	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
XppCFBP6546P_19435	COG0291	Belongs to the bacterial ribosomal protein bL35 family
XppCFBP6546P_19440	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
XppCFBP6546P_19445	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
XppCFBP6546P_19450	COG0072	phenylalanine-tRNA ligase activity
XppCFBP6546P_19450	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
XppCFBP6546P_19455	COG0776	regulation of translation
XppCFBP6546P_19500	COG0438	transferase activity, transferring glycosyl groups
XppCFBP6546P_19505	COG0438	transferase activity, transferring glycosyl groups
XppCFBP6546P_19540	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XppCFBP6546P_19550	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XppCFBP6546P_19570	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
XppCFBP6546P_19580	COG1960	acyl-CoA dehydrogenase activity
XppCFBP6546P_19590	COG3040	lipid binding
XppCFBP6546P_19605	COG0322	excinuclease ABC activity
XppCFBP6546P_19640	COG1194	a g-specific adenine glycosylase
XppCFBP6546P_19650	COG0552	protein localization to endoplasmic reticulum
XppCFBP6546P_19660	COG3938	Belongs to the proline racemase family
XppCFBP6546P_19665	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XppCFBP6546P_19680	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
XppCFBP6546P_19690	COG0006	proline dipeptidase activity
XppCFBP6546P_19705	COG0531	amino acid
XppCFBP6546P_19810	COG3328	transposase activity
XppCFBP6546P_19850	COG3328	transposase activity
XppCFBP6546P_19880	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
XppCFBP6546P_19885	COG3328	transposase activity
XppCFBP6546P_19890	COG0460	homoserine dehydrogenase
XppCFBP6546P_19890	COG0527	aspartate kinase activity
XppCFBP6546P_19925	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XppCFBP6546P_19930	COG0124	histidyl-tRNA synthetase
XppCFBP6546P_19940	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
XppCFBP6546P_19945	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
XppCFBP6546P_19950	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XppCFBP6546P_19955	COG0131	Imidazoleglycerol-phosphate dehydratase
XppCFBP6546P_19955	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
XppCFBP6546P_19960	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
XppCFBP6546P_19965	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
XppCFBP6546P_19970	COG0107	imidazoleglycerol-phosphate synthase activity
XppCFBP6546P_19975	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
XppCFBP6546P_19975	COG0140	phosphoribosyl-ATP diphosphatase activity
XppCFBP6546P_19990	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
XppCFBP6546P_20000	COG0235	Class ii aldolase
XppCFBP6546P_20005	COG0531	amino acid
XppCFBP6546P_20010	COG0531	amino acid
XppCFBP6546P_20020	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
XppCFBP6546P_20025	COG0277	FAD linked oxidase domain protein
XppCFBP6546P_20045	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
XppCFBP6546P_20090	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
XppCFBP6546P_20095	COG2258	MOSC domain
XppCFBP6546P_20100	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
XppCFBP6546P_20105	COG0505	Belongs to the CarA family
XppCFBP6546P_20115	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
XppCFBP6546P_20120	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XppCFBP6546P_20130	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
XppCFBP6546P_20150	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
XppCFBP6546P_20165	COG2198	Histidine kinase
XppCFBP6546P_20165	COG2205	protein histidine kinase activity
XppCFBP6546P_20165	COG0784	Response regulator, receiver
XppCFBP6546P_20170	COG1024	Enoyl-CoA hydratase
XppCFBP6546P_20175	COG0318	PFAM AMP-dependent synthetase and ligase
XppCFBP6546P_20210	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XppCFBP6546P_20220	COG2201	protein-glutamate methylesterase activity
XppCFBP6546P_20225	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
XppCFBP6546P_20235	COG0840	transmembrane signaling receptor activity
XppCFBP6546P_20245	COG0835	chemotaxis
XppCFBP6546P_20255	COG0840	transmembrane signaling receptor activity
XppCFBP6546P_20260	COG0840	transmembrane signaling receptor activity
XppCFBP6546P_20265	COG0840	transmembrane signaling receptor activity
XppCFBP6546P_20270	COG0840	transmembrane signaling receptor activity
XppCFBP6546P_20275	COG0840	transmembrane signaling receptor activity
XppCFBP6546P_20285	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
XppCFBP6546P_20290	COG0840	transmembrane signaling receptor activity
XppCFBP6546P_20295	COG0840	transmembrane signaling receptor activity
XppCFBP6546P_20300	COG0840	transmembrane signaling receptor activity
XppCFBP6546P_20305	COG0840	transmembrane signaling receptor activity
XppCFBP6546P_20320	COG0840	transmembrane signaling receptor activity
XppCFBP6546P_20325	COG0840	transmembrane signaling receptor activity
XppCFBP6546P_20335	COG0840	transmembrane signaling receptor activity
XppCFBP6546P_20340	COG0840	transmembrane signaling receptor activity
XppCFBP6546P_20350	COG0745	RESPONSE REGULATOR receiver
XppCFBP6546P_20360	COG0835	chemotaxis
XppCFBP6546P_20365	COG1192	Involved in chromosome partitioning
XppCFBP6546P_20370	COG1360	Flagellar Motor Protein
XppCFBP6546P_20375	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
XppCFBP6546P_20415	COG0837	glucose binding
XppCFBP6546P_20420	COG1385	rRNA (uridine-N3-)-methyltransferase activity
XppCFBP6546P_20430	COG0494	nUDIX hydrolase
XppCFBP6546P_20440	COG3956	TIGRFAM MazG family protein
XppCFBP6546P_20445	COG1742	UPF0060 membrane protein
XppCFBP6546P_20450	COG0330	HflC and HflK could
XppCFBP6546P_20460	COG0404	The glycine cleavage system catalyzes the degradation of glycine
XppCFBP6546P_20465	COG0509	glycine decarboxylation via glycine cleavage system
XppCFBP6546P_20490	COG3328	transposase activity
XppCFBP6546P_20515	COG1960	acyl-CoA dehydrogenase activity
XppCFBP6546P_20525	COG1309	transcriptional regulator
XppCFBP6546P_20530	COG4771	TonB-dependent receptor
XppCFBP6546P_20540	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
XppCFBP6546P_20545	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
XppCFBP6546P_20555	COG0516	GMP reductase activity
XppCFBP6546P_20555	COG0517	IMP dehydrogenase activity
XppCFBP6546P_20560	COG2982	Protein involved in outer membrane biogenesis
XppCFBP6546P_20565	COG1272	protein, Hemolysin III
XppCFBP6546P_20570	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
XppCFBP6546P_20575	COG0739	heme binding
XppCFBP6546P_20580	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XppCFBP6546P_20585	COG0626	cystathionine gamma-synthase activity
XppCFBP6546P_20590	COG0527	aspartate kinase activity
XppCFBP6546P_20590	COG0460	homoserine dehydrogenase
XppCFBP6546P_20600	COG1760	l-serine dehydratase
XppCFBP6546P_20620	COG2353	YceI-like domain
XppCFBP6546P_20650	COG2814	Major facilitator Superfamily
XppCFBP6546P_20655	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
XppCFBP6546P_20665	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
XppCFBP6546P_20670	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
XppCFBP6546P_20675	COG0259	pyridoxamine-phosphate oxidase activity
XppCFBP6546P_20685	COG1842	Phage shock protein A
XppCFBP6546P_20710	COG0754	glutathionylspermidine amidase activity
XppCFBP6546P_20720	COG2814	Major facilitator Superfamily
XppCFBP6546P_20810	COG0531	amino acid
XppCFBP6546P_20815	COG2197	response regulator
XppCFBP6546P_20845	COG1113	amino acid transport
XppCFBP6546P_20855	COG1271	oxidase subunit
XppCFBP6546P_20930	COG2951	lytic endotransglycosylase activity
XppCFBP6546P_20945	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
XppCFBP6546P_20945	COG0551	DNA topoisomerase type I activity
XppCFBP6546P_20990	COG1294	oxidase, subunit
XppCFBP6546P_21000	COG2239	Acts as a magnesium transporter
XppCFBP6546P_21015	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
XppCFBP6546P_21025	COG1660	Displays ATPase and GTPase activities
XppCFBP6546P_21030	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
XppCFBP6546P_21035	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
XppCFBP6546P_21050	COG1137	ATPase activity
XppCFBP6546P_21055	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
XppCFBP6546P_21065	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
XppCFBP6546P_21075	COG0271	Belongs to the BolA IbaG family
XppCFBP6546P_21080	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
XppCFBP6546P_21100	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
XppCFBP6546P_21115	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
XppCFBP6546P_21135	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
XppCFBP6546P_21155	COG1555	photosystem II stabilization
XppCFBP6546P_21165	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
XppCFBP6546P_21170	COG1477	protein flavinylation
XppCFBP6546P_21175	COG3328	transposase activity
XppCFBP6546P_21200	COG3128	pkhd-type hydroxylase
XppCFBP6546P_21205	COG4774	siderophore transport
XppCFBP6546P_21215	COG0456	acetyltransferase
XppCFBP6546P_21220	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
XppCFBP6546P_21225	COG0719	Fe-S assembly protein
XppCFBP6546P_21230	COG0396	ATPase activity
XppCFBP6546P_21235	COG0719	Fe-S assembly protein
XppCFBP6546P_21240	COG1959	2 iron, 2 sulfur cluster binding
XppCFBP6546P_21250	COG0693	protein deglycase activity
XppCFBP6546P_21270	COG0739	heme binding
XppCFBP6546P_21285	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
XppCFBP6546P_21310	COG0519	Catalyzes the synthesis of GMP from XMP
XppCFBP6546P_21320	COG1678	Uncharacterized ACR, COG1678
XppCFBP6546P_21325	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
XppCFBP6546P_21330	COG0540	Belongs to the ATCase OTCase family
XppCFBP6546P_21335	COG1764	response to oxidative stress
XppCFBP6546P_21345	COG0384	phenazine biosynthesis protein PhzF
XppCFBP6546P_21350	COG0384	phenazine biosynthesis protein PhzF
XppCFBP6546P_21355	COG0527	aspartate kinase activity
XppCFBP6546P_21370	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
XppCFBP6546P_21380	COG0142	geranyltranstransferase activity
XppCFBP6546P_21385	COG0629	single-stranded DNA binding
XppCFBP6546P_21390	COG2203	Gaf domain
XppCFBP6546P_21390	COG3706	GGDEF domain
XppCFBP6546P_21390	COG4251	negative regulation of phosphorylation
XppCFBP6546P_21390	COG5001	Diguanylate cyclase
XppCFBP6546P_21395	COG0604	alcohol dehydrogenase
XppCFBP6546P_21395	COG1028	Short-chain dehydrogenase reductase Sdr
XppCFBP6546P_21395	COG3321	synthase
XppCFBP6546P_21400	COG2080	2 iron, 2 sulfur cluster binding
XppCFBP6546P_21405	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
XppCFBP6546P_21410	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XppCFBP6546P_21415	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
XppCFBP6546P_21460	COG2879	small protein
XppCFBP6546P_21465	COG1966	Carbon starvation protein
XppCFBP6546P_21470	COG1741	Belongs to the pirin family
XppCFBP6546P_21485	COG1741	Belongs to the pirin family
XppCFBP6546P_21495	COG1515	deoxyribonuclease V activity
XppCFBP6546P_21510	COG3590	peptidase
XppCFBP6546P_21520	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XppCFBP6546P_21525	COG2201	protein-glutamate methylesterase activity
XppCFBP6546P_21530	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
XppCFBP6546P_21535	COG2199	diguanylate cyclase activity
XppCFBP6546P_21535	COG2202	Pas domain
XppCFBP6546P_21535	COG2200	EAL domain
XppCFBP6546P_21540	COG0835	chemotaxis
XppCFBP6546P_21545	COG0840	transmembrane signaling receptor activity
XppCFBP6546P_21550	COG2198	Histidine kinase
XppCFBP6546P_21550	COG0643	Histidine kinase
XppCFBP6546P_21560	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
XppCFBP6546P_21570	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
XppCFBP6546P_21575	COG0745	RESPONSE REGULATOR receiver
XppCFBP6546P_21595	COG4452	Inner membrane protein CreD
XppCFBP6546P_21620	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
XppCFBP6546P_21625	COG0735	belongs to the Fur family
XppCFBP6546P_21640	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XppCFBP6546P_21645	COG1538	Outer membrane efflux protein
XppCFBP6546P_21650	COG1309	transcriptional regulator
XppCFBP6546P_21660	COG2207	Transcriptional regulator
XppCFBP6546P_21675	COG2814	Major facilitator Superfamily
XppCFBP6546P_21680	COG0667	Aldo Keto reductase
XppCFBP6546P_21795	COG1595	DNA-templated transcription, initiation
XppCFBP6546P_21805	COG5001	Diguanylate cyclase
XppCFBP6546P_21805	COG5002	protein histidine kinase activity
XppCFBP6546P_21810	COG1187	pseudouridine synthase activity
XppCFBP6546P_21815	COG0745	RESPONSE REGULATOR receiver
XppCFBP6546P_21815	COG3706	GGDEF domain
XppCFBP6546P_21830	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
XppCFBP6546P_21835	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
XppCFBP6546P_21840	COG0475	glutathione-regulated potassium exporter activity
XppCFBP6546P_21845	COG5000	phosphorelay sensor kinase activity
XppCFBP6546P_21845	COG5002	protein histidine kinase activity
XppCFBP6546P_21850	COG0745	RESPONSE REGULATOR receiver
XppCFBP6546P_21880	COG1132	(ABC) transporter
XppCFBP6546P_21925	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
XppCFBP6546P_21930	COG2155	Conserved Protein
XppCFBP6546P_21935	COG5487	UPF0391 membrane protein
XppCFBP6546P_21955	COG3118	belongs to the thioredoxin family
XppCFBP6546P_21965	COG0495	leucyl-tRNA aminoacylation
XppCFBP6546P_21985	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
XppCFBP6546P_22000	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
XppCFBP6546P_22015	COG2968	Membrane
XppCFBP6546P_22020	COG0424	maF-like protein
XppCFBP6546P_22025	COG1530	ribonuclease E activity
XppCFBP6546P_22030	COG3164	Protein of unknown function
XppCFBP6546P_22045	COG3028	Belongs to the UPF0307 family
XppCFBP6546P_22050	COG0312	modulator of DNA gyrase
XppCFBP6546P_22060	COG4104	PAAR repeat-containing protein
XppCFBP6546P_22065	COG0142	geranyltranstransferase activity
XppCFBP6546P_22070	COG1722	exodeoxyribonuclease VII activity
XppCFBP6546P_22075	COG0037	tRNA processing
XppCFBP6546P_22085	COG1785	Belongs to the alkaline phosphatase family
XppCFBP6546P_22090	COG1301	dicarboxylic acid transport
XppCFBP6546P_22095	COG4106	trans-aconitate 2-methyltransferase activity
XppCFBP6546P_22105	COG0791	NLP P60 protein
XppCFBP6546P_22115	COG1047	Peptidyl-prolyl cis-trans
XppCFBP6546P_22120	COG2311	Membrane
XppCFBP6546P_22125	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XppCFBP6546P_22155	COG3590	peptidase
XppCFBP6546P_22185	COG0489	protein tyrosine kinase activity
XppCFBP6546P_22195	COG0717	Belongs to the dCTP deaminase family
XppCFBP6546P_22215	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
XppCFBP6546P_22220	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XppCFBP6546P_22245	COG0433	COG0433 Predicted ATPase
XppCFBP6546P_22270	COG2890	protein-(glutamine-N5) methyltransferase activity
XppCFBP6546P_22275	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
XppCFBP6546P_22280	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
XppCFBP6546P_22285	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
XppCFBP6546P_22300	COG0101	tRNA pseudouridine synthase activity
XppCFBP6546P_22305	COG0135	phosphoribosylanthranilate isomerase activity
XppCFBP6546P_22315	COG0133	tryptophan synthase activity
XppCFBP6546P_22325	COG0159	tryptophan synthase activity
XppCFBP6546P_22330	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
XppCFBP6546P_22335	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
XppCFBP6546P_22365	COG4221	oxidoreductase activity
XppCFBP6546P_22370	COG0149	triose-phosphate isomerase activity
XppCFBP6546P_22385	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XppCFBP6546P_22390	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XppCFBP6546P_22395	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XppCFBP6546P_22400	COG0649	NAD binding
XppCFBP6546P_22405	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
XppCFBP6546P_22410	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
XppCFBP6546P_22420	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
XppCFBP6546P_22425	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XppCFBP6546P_22435	COG0713	ATP synthesis coupled electron transport
XppCFBP6546P_22450	COG1007	ATP synthesis coupled electron transport
XppCFBP6546P_22460	COG0779	Required for maturation of 30S ribosomal subunits
XppCFBP6546P_22465	COG0195	Participates in both transcription termination and antitermination
XppCFBP6546P_22475	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
XppCFBP6546P_22480	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
XppCFBP6546P_22485	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
XppCFBP6546P_22490	COG1185	polyribonucleotide nucleotidyltransferase activity
XppCFBP6546P_22520	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
XppCFBP6546P_22525	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
XppCFBP6546P_22535	COG2095	MarC family integral membrane protein
XppCFBP6546P_22550	COG1611	Belongs to the LOG family
XppCFBP6546P_22630	COG4695	Portal protein
XppCFBP6546P_22635	COG4695	Portal protein
XppCFBP6546P_22780	COG3328	transposase activity
XppCFBP6546P_22805	COG4962	Type ii secretion system protein e
XppCFBP6546P_22830	COG3846	protein secretion by the type IV secretion system
XppCFBP6546P_22895	COG1487	ribonuclease activity
XppCFBP6546P_22900	COG4691	Plasmid stability protein
XppCFBP6546P_22905	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
XppCFBP6546P_22940	COG3328	transposase activity
XppCFBP6546P_23150	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
XppCFBP6546P_23275	COG3039	Transposase
XppCFBP6546P_23305	COG3328	transposase activity
XppCFBP6546P_23385	COG3328	transposase activity
XppCFBP6546P_23430	COG1487	ribonuclease activity
XppCFBP6546P_23435	COG4691	Plasmid stability protein
XppCFBP6546P_23440	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
XppCFBP6546P_23550	COG4691	Plasmid stability protein
XppCFBP6546P_23555	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs