locus-tag	class	description
XppCFBP6982P_00030	COG2226	methyltransferase
XppCFBP6982P_00030	COG1073	alpha beta
XppCFBP6982P_00045	COG0363	glucosamine-6-phosphate deaminase activity
XppCFBP6982P_00085	COG1309	transcriptional regulator
XppCFBP6982P_00100	COG2154	pterin-4-alpha-carbinolamine dehydratase
XppCFBP6982P_00110	COG0428	transporter
XppCFBP6982P_00115	COG3064	Membrane
XppCFBP6982P_00125	COG1530	ribonuclease E activity
XppCFBP6982P_00130	COG3039	Transposase
XppCFBP6982P_00160	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
XppCFBP6982P_00185	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
XppCFBP6982P_00190	COG0322	excinuclease ABC activity
XppCFBP6982P_00200	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
XppCFBP6982P_00205	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
XppCFBP6982P_00210	COG1663	tetraacyldisaccharide 4'-kinase activity
XppCFBP6982P_00215	COG1132	(ABC) transporter
XppCFBP6982P_00225	COG0811	peptide transport
XppCFBP6982P_00240	COG1136	(ABC) transporter
XppCFBP6982P_00245	COG4591	ABC-type transport system involved in lipoprotein release permease component
XppCFBP6982P_00255	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
XppCFBP6982P_00260	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
XppCFBP6982P_00275	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
XppCFBP6982P_00290	COG0354	folic acid binding
XppCFBP6982P_00300	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
XppCFBP6982P_00305	COG0837	glucose binding
XppCFBP6982P_00310	COG0363	glucosamine-6-phosphate deaminase activity
XppCFBP6982P_00315	COG0129	dihydroxy-acid dehydratase activity
XppCFBP6982P_00320	COG0800	Aldolase
XppCFBP6982P_00385	COG0784	Response regulator, receiver
XppCFBP6982P_00385	COG2205	protein histidine kinase activity
XppCFBP6982P_00390	COG2183	response to ionizing radiation
XppCFBP6982P_00400	COG0723	plastoquinol--plastocyanin reductase activity
XppCFBP6982P_00400	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XppCFBP6982P_00415	COG3243	poly(R)-hydroxyalkanoic acid synthase
XppCFBP6982P_00425	COG1183	phosphatidylcholine synthase activity
XppCFBP6982P_00430	COG1028	Short-chain dehydrogenase reductase Sdr
XppCFBP6982P_00445	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
XppCFBP6982P_00460	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
XppCFBP6982P_00465	COG0590	tRNA wobble adenosine to inosine editing
XppCFBP6982P_00470	COG1321	iron dependent repressor
XppCFBP6982P_00475	COG1914	H( )-stimulated, divalent metal cation uptake system
XppCFBP6982P_00495	COG2814	Major facilitator Superfamily
XppCFBP6982P_00510	COG1335	isochorismatase
XppCFBP6982P_00530	COG2197	response regulator
XppCFBP6982P_00560	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
XppCFBP6982P_00565	COG3002	Belongs to the UPF0753 family
XppCFBP6982P_00575	COG0604	alcohol dehydrogenase
XppCFBP6982P_00580	COG3384	dioxygenase
XppCFBP6982P_00610	COG0583	DNA-binding transcription factor activity
XppCFBP6982P_00655	COG0519	Catalyzes the synthesis of GMP from XMP
XppCFBP6982P_00655	COG0518	GMP synthase (glutamine-hydrolyzing) activity
XppCFBP6982P_00665	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
XppCFBP6982P_00675	COG0475	glutathione-regulated potassium exporter activity
XppCFBP6982P_00675	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
XppCFBP6982P_00680	COG1210	Utp--glucose-1-phosphate uridylyltransferase
XppCFBP6982P_00690	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
XppCFBP6982P_00695	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
XppCFBP6982P_00705	COG0776	regulation of translation
XppCFBP6982P_00710	COG0539	negative regulation of cytoplasmic translation
XppCFBP6982P_00715	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
XppCFBP6982P_00720	COG0257	Belongs to the bacterial ribosomal protein bL36 family
XppCFBP6982P_00730	COG2957	Belongs to the agmatine deiminase family
XppCFBP6982P_00735	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XppCFBP6982P_00760	COG0395	ABC-type sugar transport system, permease component
XppCFBP6982P_00765	COG1175	transmembrane transport
XppCFBP6982P_00800	COG2350	Protein conserved in bacteria
XppCFBP6982P_00805	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
XppCFBP6982P_00810	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
XppCFBP6982P_00815	COG1187	pseudouridine synthase activity
XppCFBP6982P_00830	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XppCFBP6982P_00835	COG0436	Aminotransferase
XppCFBP6982P_00840	COG4133	protoheme IX ABC transporter activity
XppCFBP6982P_00860	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
XppCFBP6982P_00885	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XppCFBP6982P_00895	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
XppCFBP6982P_00900	COG4988	ABC transporter
XppCFBP6982P_00910	COG1294	oxidase, subunit
XppCFBP6982P_00940	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
XppCFBP6982P_00945	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
XppCFBP6982P_00955	COG0165	Argininosuccinate lyase
XppCFBP6982P_00960	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
XppCFBP6982P_00970	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
XppCFBP6982P_00985	COG0137	argininosuccinate synthase activity
XppCFBP6982P_00990	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
XppCFBP6982P_01000	COG0215	cysteine-tRNA ligase activity
XppCFBP6982P_01005	COG2166	iron-sulfur cluster assembly
XppCFBP6982P_01015	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
XppCFBP6982P_01020	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
XppCFBP6982P_01025	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
XppCFBP6982P_01055	COG4302	ethanolamine ammonia-lyase activity
XppCFBP6982P_01085	COG3039	Transposase
XppCFBP6982P_01115	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
XppCFBP6982P_01120	COG0402	S-adenosylhomocysteine deaminase activity
XppCFBP6982P_01130	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
XppCFBP6982P_01135	COG1509	lysine 2,3-aminomutase activity
XppCFBP6982P_01140	COG3300	MHYT domain
XppCFBP6982P_01140	COG5001	Diguanylate cyclase
XppCFBP6982P_01155	COG0483	inositol monophosphate 1-phosphatase activity
XppCFBP6982P_01180	COG0513	Belongs to the DEAD box helicase family
XppCFBP6982P_01185	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
XppCFBP6982P_01190	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
XppCFBP6982P_01210	COG0625	glutathione transferase activity
XppCFBP6982P_01220	COG4681	YaeQ
XppCFBP6982P_01225	COG2081	HI0933 family
XppCFBP6982P_01235	COG0501	Belongs to the peptidase M48B family
XppCFBP6982P_01240	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
XppCFBP6982P_01245	COG1028	Short-chain dehydrogenase reductase Sdr
XppCFBP6982P_01270	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
XppCFBP6982P_01275	COG0860	N-Acetylmuramoyl-L-alanine amidase
XppCFBP6982P_01280	COG0802	atpase or kinase
XppCFBP6982P_01285	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
XppCFBP6982P_01285	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
XppCFBP6982P_01290	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
XppCFBP6982P_01295	COG1570	exodeoxyribonuclease VII activity
XppCFBP6982P_01310	COG1262	PFAM Formylglycine-generating sulfatase enzyme
XppCFBP6982P_01355	COG0835	chemotaxis
XppCFBP6982P_01360	COG0840	transmembrane signaling receptor activity
XppCFBP6982P_01365	COG2094	Belongs to the DNA glycosylase MPG family
XppCFBP6982P_01370	COG1201	RNA secondary structure unwinding
XppCFBP6982P_01390	COG2969	positive regulation of protein catabolic process
XppCFBP6982P_01395	COG0625	glutathione transferase activity
XppCFBP6982P_01400	COG2857	Cytochrome c1
XppCFBP6982P_01405	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
XppCFBP6982P_01410	COG0723	plastoquinol--plastocyanin reductase activity
XppCFBP6982P_01420	COG0741	lytic transglycosylase activity
XppCFBP6982P_01435	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
XppCFBP6982P_01440	COG1702	phosphate starvation-inducible protein PhoH
XppCFBP6982P_01450	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
XppCFBP6982P_01460	COG4535	Mg2 and Co2 transporter CorC
XppCFBP6982P_01475	COG1012	belongs to the aldehyde dehydrogenase family
XppCFBP6982P_01480	COG1177	transmembrane transport
XppCFBP6982P_01485	COG1176	ABC-type spermidine putrescine transport system, permease component I
XppCFBP6982P_01490	COG3842	ATPase activity
XppCFBP6982P_01510	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
XppCFBP6982P_01525	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
XppCFBP6982P_01530	COG0174	glutamine synthetase
XppCFBP6982P_01535	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XppCFBP6982P_01540	COG0745	RESPONSE REGULATOR receiver
XppCFBP6982P_01540	COG3706	GGDEF domain
XppCFBP6982P_01545	COG2703	oxygen carrier activity
XppCFBP6982P_01550	COG0477	Major facilitator Superfamily
XppCFBP6982P_01560	COG0243	molybdopterin cofactor binding
XppCFBP6982P_01565	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
XppCFBP6982P_01595	COG2733	membrane
XppCFBP6982P_01600	COG0784	Response regulator, receiver
XppCFBP6982P_01600	COG2205	protein histidine kinase activity
XppCFBP6982P_01600	COG5002	protein histidine kinase activity
XppCFBP6982P_01610	COG0477	Major facilitator Superfamily
XppCFBP6982P_01615	COG0840	transmembrane signaling receptor activity
XppCFBP6982P_01645	COG2902	Dehydrogenase
XppCFBP6982P_01655	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XppCFBP6982P_01660	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XppCFBP6982P_01665	COG1609	Transcriptional regulator
XppCFBP6982P_01670	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
XppCFBP6982P_01670	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
XppCFBP6982P_01675	COG1105	Belongs to the carbohydrate kinase PfkB family
XppCFBP6982P_01680	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
XppCFBP6982P_01680	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
XppCFBP6982P_01700	COG3328	transposase activity
XppCFBP6982P_01720	COG3328	transposase activity
XppCFBP6982P_01730	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
XppCFBP6982P_01740	COG1862	Preprotein translocase
XppCFBP6982P_01745	COG0343	queuine tRNA-ribosyltransferase activity
XppCFBP6982P_01750	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
XppCFBP6982P_01790	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
XppCFBP6982P_01795	COG3291	Pkd domain containing protein
XppCFBP6982P_01800	COG0405	Gamma-glutamyltransferase
XppCFBP6982P_01805	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
XppCFBP6982P_01820	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
XppCFBP6982P_01825	COG0742	ribosomal rna small subunit methyltransferase
XppCFBP6982P_01830	COG0326	Molecular chaperone. Has ATPase activity
XppCFBP6982P_01910	COG3702	type iv secretory pathway
XppCFBP6982P_01930	COG2948	multi-organism process
XppCFBP6982P_01950	COG3505	Type IV secretory pathway VirD4
XppCFBP6982P_01965	COG0556	nucleotide-excision repair
XppCFBP6982P_01970	COG3039	Transposase
XppCFBP6982P_02135	COG3179	chitinase
XppCFBP6982P_02185	COG4695	Portal protein
XppCFBP6982P_02225	COG3328	transposase activity
XppCFBP6982P_02265	COG3275	phosphorelay sensor kinase activity
XppCFBP6982P_02270	COG1611	Belongs to the LOG family
XppCFBP6982P_02285	COG2095	MarC family integral membrane protein
XppCFBP6982P_02295	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
XppCFBP6982P_02300	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
XppCFBP6982P_02330	COG1185	polyribonucleotide nucleotidyltransferase activity
XppCFBP6982P_02335	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
XppCFBP6982P_02340	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
XppCFBP6982P_02345	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
XppCFBP6982P_02350	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
XppCFBP6982P_02355	COG0195	Participates in both transcription termination and antitermination
XppCFBP6982P_02360	COG0779	Required for maturation of 30S ribosomal subunits
XppCFBP6982P_02370	COG1007	ATP synthesis coupled electron transport
XppCFBP6982P_02385	COG0713	ATP synthesis coupled electron transport
XppCFBP6982P_02395	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XppCFBP6982P_02400	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
XppCFBP6982P_02410	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
XppCFBP6982P_02415	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
XppCFBP6982P_02420	COG0649	NAD binding
XppCFBP6982P_02425	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XppCFBP6982P_02430	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XppCFBP6982P_02435	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XppCFBP6982P_02450	COG0149	triose-phosphate isomerase activity
XppCFBP6982P_02455	COG4221	oxidoreductase activity
XppCFBP6982P_02485	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
XppCFBP6982P_02490	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
XppCFBP6982P_02495	COG0159	tryptophan synthase activity
XppCFBP6982P_02505	COG0133	tryptophan synthase activity
XppCFBP6982P_02515	COG0135	phosphoribosylanthranilate isomerase activity
XppCFBP6982P_02520	COG0101	tRNA pseudouridine synthase activity
XppCFBP6982P_02535	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
XppCFBP6982P_02540	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
XppCFBP6982P_02545	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
XppCFBP6982P_02550	COG2890	protein-(glutamine-N5) methyltransferase activity
XppCFBP6982P_02560	COG0688	phosphatidylethanolamine metabolic process
XppCFBP6982P_02570	COG0433	COG0433 Predicted ATPase
XppCFBP6982P_02595	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XppCFBP6982P_02600	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
XppCFBP6982P_02620	COG0717	Belongs to the dCTP deaminase family
XppCFBP6982P_02630	COG0489	protein tyrosine kinase activity
XppCFBP6982P_02660	COG3590	peptidase
XppCFBP6982P_02685	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XppCFBP6982P_02690	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XppCFBP6982P_02695	COG2311	Membrane
XppCFBP6982P_02700	COG1047	Peptidyl-prolyl cis-trans
XppCFBP6982P_02705	COG0791	NLP P60 protein
XppCFBP6982P_02710	COG0791	NLP P60 protein
XppCFBP6982P_02720	COG4106	trans-aconitate 2-methyltransferase activity
XppCFBP6982P_02725	COG1301	dicarboxylic acid transport
XppCFBP6982P_02730	COG1785	Belongs to the alkaline phosphatase family
XppCFBP6982P_02740	COG0037	tRNA processing
XppCFBP6982P_02745	COG1722	exodeoxyribonuclease VII activity
XppCFBP6982P_02750	COG0142	geranyltranstransferase activity
XppCFBP6982P_02755	COG4104	PAAR repeat-containing protein
XppCFBP6982P_02765	COG0312	modulator of DNA gyrase
XppCFBP6982P_02770	COG3028	Belongs to the UPF0307 family
XppCFBP6982P_02775	COG0312	modulator of DNA gyrase
XppCFBP6982P_02785	COG3164	Protein of unknown function
XppCFBP6982P_02790	COG1530	ribonuclease E activity
XppCFBP6982P_02795	COG0424	maF-like protein
XppCFBP6982P_02800	COG2968	Membrane
XppCFBP6982P_02815	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
XppCFBP6982P_02830	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
XppCFBP6982P_02850	COG0495	leucyl-tRNA aminoacylation
XppCFBP6982P_02860	COG3118	belongs to the thioredoxin family
XppCFBP6982P_02880	COG5487	UPF0391 membrane protein
XppCFBP6982P_02885	COG2155	Conserved Protein
XppCFBP6982P_02890	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
XppCFBP6982P_02935	COG1132	(ABC) transporter
XppCFBP6982P_02965	COG0745	RESPONSE REGULATOR receiver
XppCFBP6982P_02970	COG5000	phosphorelay sensor kinase activity
XppCFBP6982P_02970	COG5002	protein histidine kinase activity
XppCFBP6982P_02975	COG0475	glutathione-regulated potassium exporter activity
XppCFBP6982P_02980	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
XppCFBP6982P_02985	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
XppCFBP6982P_03000	COG0745	RESPONSE REGULATOR receiver
XppCFBP6982P_03000	COG3706	GGDEF domain
XppCFBP6982P_03005	COG1187	pseudouridine synthase activity
XppCFBP6982P_03010	COG5001	Diguanylate cyclase
XppCFBP6982P_03010	COG5002	protein histidine kinase activity
XppCFBP6982P_03020	COG1595	DNA-templated transcription, initiation
XppCFBP6982P_03135	COG0667	Aldo Keto reductase
XppCFBP6982P_03140	COG2814	Major facilitator Superfamily
XppCFBP6982P_03145	COG0583	DNA-binding transcription factor activity
XppCFBP6982P_03155	COG2207	Transcriptional regulator
XppCFBP6982P_03165	COG1309	transcriptional regulator
XppCFBP6982P_03170	COG1538	Outer membrane efflux protein
XppCFBP6982P_03175	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XppCFBP6982P_03190	COG0735	belongs to the Fur family
XppCFBP6982P_03195	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
XppCFBP6982P_03220	COG4452	Inner membrane protein CreD
XppCFBP6982P_03240	COG0745	RESPONSE REGULATOR receiver
XppCFBP6982P_03245	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
XppCFBP6982P_03255	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
XppCFBP6982P_03265	COG0643	Histidine kinase
XppCFBP6982P_03265	COG2198	Histidine kinase
XppCFBP6982P_03270	COG0840	transmembrane signaling receptor activity
XppCFBP6982P_03275	COG0835	chemotaxis
XppCFBP6982P_03280	COG2200	EAL domain
XppCFBP6982P_03280	COG2202	Pas domain
XppCFBP6982P_03280	COG2199	diguanylate cyclase activity
XppCFBP6982P_03285	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
XppCFBP6982P_03290	COG2201	protein-glutamate methylesterase activity
XppCFBP6982P_03295	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XppCFBP6982P_03305	COG3590	peptidase
XppCFBP6982P_03320	COG1515	deoxyribonuclease V activity
XppCFBP6982P_03330	COG1741	Belongs to the pirin family
XppCFBP6982P_03345	COG1741	Belongs to the pirin family
XppCFBP6982P_03350	COG1966	Carbon starvation protein
XppCFBP6982P_03355	COG2879	small protein
XppCFBP6982P_03400	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
XppCFBP6982P_03405	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XppCFBP6982P_03410	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
XppCFBP6982P_03415	COG2080	2 iron, 2 sulfur cluster binding
XppCFBP6982P_03420	COG0604	alcohol dehydrogenase
XppCFBP6982P_03420	COG1028	Short-chain dehydrogenase reductase Sdr
XppCFBP6982P_03420	COG3321	synthase
XppCFBP6982P_03425	COG2203	Gaf domain
XppCFBP6982P_03425	COG3706	GGDEF domain
XppCFBP6982P_03425	COG4251	negative regulation of phosphorylation
XppCFBP6982P_03425	COG5001	Diguanylate cyclase
XppCFBP6982P_03430	COG0629	single-stranded DNA binding
XppCFBP6982P_03435	COG0142	geranyltranstransferase activity
XppCFBP6982P_03445	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
XppCFBP6982P_03460	COG0527	aspartate kinase activity
XppCFBP6982P_03465	COG0384	phenazine biosynthesis protein PhzF
XppCFBP6982P_03470	COG0384	phenazine biosynthesis protein PhzF
XppCFBP6982P_03480	COG1764	response to oxidative stress
XppCFBP6982P_03485	COG0540	Belongs to the ATCase OTCase family
XppCFBP6982P_03490	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
XppCFBP6982P_03495	COG1678	Uncharacterized ACR, COG1678
XppCFBP6982P_03500	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
XppCFBP6982P_03505	COG0519	Catalyzes the synthesis of GMP from XMP
XppCFBP6982P_03530	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
XppCFBP6982P_03545	COG0739	heme binding
XppCFBP6982P_03565	COG0693	protein deglycase activity
XppCFBP6982P_03575	COG1959	2 iron, 2 sulfur cluster binding
XppCFBP6982P_03580	COG0719	Fe-S assembly protein
XppCFBP6982P_03585	COG0396	ATPase activity
XppCFBP6982P_03590	COG0719	Fe-S assembly protein
XppCFBP6982P_03595	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
XppCFBP6982P_03600	COG0456	acetyltransferase
XppCFBP6982P_03610	COG4774	siderophore transport
XppCFBP6982P_03615	COG3128	pkhd-type hydroxylase
XppCFBP6982P_03640	COG3328	transposase activity
XppCFBP6982P_03645	COG1477	protein flavinylation
XppCFBP6982P_03650	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
XppCFBP6982P_03660	COG1555	photosystem II stabilization
XppCFBP6982P_03680	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
XppCFBP6982P_03690	COG0628	permease
XppCFBP6982P_03700	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
XppCFBP6982P_03715	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
XppCFBP6982P_03735	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
XppCFBP6982P_03740	COG0271	Belongs to the BolA IbaG family
XppCFBP6982P_03750	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
XppCFBP6982P_03760	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
XppCFBP6982P_03765	COG1137	ATPase activity
XppCFBP6982P_03780	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
XppCFBP6982P_03785	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
XppCFBP6982P_03790	COG1660	Displays ATPase and GTPase activities
XppCFBP6982P_03800	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
XppCFBP6982P_03805	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
XppCFBP6982P_03815	COG2239	Acts as a magnesium transporter
XppCFBP6982P_03825	COG1294	oxidase, subunit
XppCFBP6982P_03835	COG1271	oxidase subunit
XppCFBP6982P_03845	COG1113	amino acid transport
XppCFBP6982P_03875	COG2197	response regulator
XppCFBP6982P_03880	COG0531	amino acid
XppCFBP6982P_03970	COG2814	Major facilitator Superfamily
XppCFBP6982P_03980	COG0754	glutathionylspermidine amidase activity
XppCFBP6982P_04005	COG1842	Phage shock protein A
XppCFBP6982P_04015	COG0259	pyridoxamine-phosphate oxidase activity
XppCFBP6982P_04020	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
XppCFBP6982P_04025	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
XppCFBP6982P_04035	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
XppCFBP6982P_04040	COG2814	Major facilitator Superfamily
XppCFBP6982P_04065	COG0784	Response regulator, receiver
XppCFBP6982P_04065	COG2198	Histidine kinase
XppCFBP6982P_04065	COG2205	protein histidine kinase activity
XppCFBP6982P_04070	COG2353	YceI-like domain
XppCFBP6982P_04090	COG1760	l-serine dehydratase
XppCFBP6982P_04100	COG0527	aspartate kinase activity
XppCFBP6982P_04100	COG0460	homoserine dehydrogenase
XppCFBP6982P_04105	COG0626	cystathionine gamma-synthase activity
XppCFBP6982P_04110	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XppCFBP6982P_04115	COG0739	heme binding
XppCFBP6982P_04120	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
XppCFBP6982P_04125	COG1272	protein, Hemolysin III
XppCFBP6982P_04130	COG2982	Protein involved in outer membrane biogenesis
XppCFBP6982P_04135	COG0517	IMP dehydrogenase activity
XppCFBP6982P_04135	COG0516	GMP reductase activity
XppCFBP6982P_04140	COG0463	Glycosyl transferase, family 2
XppCFBP6982P_04145	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
XppCFBP6982P_04150	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
XppCFBP6982P_04160	COG4771	TonB-dependent receptor
XppCFBP6982P_04165	COG1309	transcriptional regulator
XppCFBP6982P_04175	COG1960	acyl-CoA dehydrogenase activity
XppCFBP6982P_04200	COG3328	transposase activity
XppCFBP6982P_04225	COG0509	glycine decarboxylation via glycine cleavage system
XppCFBP6982P_04230	COG0404	The glycine cleavage system catalyzes the degradation of glycine
XppCFBP6982P_04240	COG0330	HflC and HflK could
XppCFBP6982P_04245	COG1742	UPF0060 membrane protein
XppCFBP6982P_04250	COG3956	TIGRFAM MazG family protein
XppCFBP6982P_04260	COG0494	nUDIX hydrolase
XppCFBP6982P_04270	COG1385	rRNA (uridine-N3-)-methyltransferase activity
XppCFBP6982P_04275	COG0837	glucose binding
XppCFBP6982P_04300	COG3858	chitin binding
XppCFBP6982P_04300	COG1388	LysM domain
XppCFBP6982P_04305	COG3525	Glycosyl hydrolase, family 20, catalytic domain
XppCFBP6982P_04315	COG1472	Belongs to the glycosyl hydrolase 3 family
XppCFBP6982P_04325	COG3537	Alpha-1,2-mannosidase
XppCFBP6982P_04370	COG3142	Participates in the control of copper homeostasis
XppCFBP6982P_04375	COG1446	asparaginase
XppCFBP6982P_04410	COG0840	transmembrane signaling receptor activity
XppCFBP6982P_04430	COG0189	ligase activity
XppCFBP6982P_04440	COG1397	ADP-ribosylglycohydrolase
XppCFBP6982P_04450	COG1199	ATP-dependent helicase activity
XppCFBP6982P_04460	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
XppCFBP6982P_04465	COG1215	transferase activity, transferring glycosyl groups
XppCFBP6982P_04480	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
XppCFBP6982P_04490	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
XppCFBP6982P_04495	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
XppCFBP6982P_04500	COG0535	radical SAM domain protein
XppCFBP6982P_04505	COG0535	radical SAM domain protein
XppCFBP6982P_04520	COG0837	glucose binding
XppCFBP6982P_04530	COG3328	transposase activity
XppCFBP6982P_04540	COG1643	Atp-dependent helicase
XppCFBP6982P_04545	COG0783	Belongs to the Dps family
XppCFBP6982P_04550	COG0514	ATP-dependent DNA helicase (RecQ)
XppCFBP6982P_04585	COG0840	transmembrane signaling receptor activity
XppCFBP6982P_04605	COG3920	Histidine kinase
XppCFBP6982P_04620	COG0602	queuosine metabolic process
XppCFBP6982P_04630	COG2885	chlorophyll binding
XppCFBP6982P_04635	COG0823	Involved in the tonB-independent uptake of proteins
XppCFBP6982P_04645	COG0848	biopolymer transport protein
XppCFBP6982P_04655	COG0824	Thioesterase
XppCFBP6982P_04660	COG2255	four-way junction helicase activity
XppCFBP6982P_04670	COG3158	transport of potassium into the cell
XppCFBP6982P_04675	COG0632	four-way junction helicase activity
XppCFBP6982P_04680	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
XppCFBP6982P_04685	COG0217	transcriptional regulatory protein
XppCFBP6982P_04700	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
XppCFBP6982P_04715	COG0477	Major facilitator Superfamily
XppCFBP6982P_04740	COG0657	acetylesterase activity
XppCFBP6982P_04740	COG2755	lipolytic protein G-D-S-L family
XppCFBP6982P_04760	COG0488	(ABC) transporter
XppCFBP6982P_04795	COG4651	solute:proton antiporter activity
XppCFBP6982P_04795	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
XppCFBP6982P_04810	COG3328	transposase activity
XppCFBP6982P_04825	COG4772	TonB-dependent receptor
XppCFBP6982P_04835	COG4264	IucA IucC family
XppCFBP6982P_04850	COG0019	diaminopimelate decarboxylase activity
XppCFBP6982P_04875	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
XppCFBP6982P_04885	COG1492	cobalamin metabolic process
XppCFBP6982P_04895	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
XppCFBP6982P_04920	COG4206	TonB-dependent receptor
XppCFBP6982P_04930	COG0542	response to heat
XppCFBP6982P_04980	COG1877	trehalose-phosphatase activity
XppCFBP6982P_04985	COG3387	PFAM Glycoside hydrolase 15-related
XppCFBP6982P_05010	COG0840	transmembrane signaling receptor activity
XppCFBP6982P_05015	COG3011	Protein conserved in bacteria
XppCFBP6982P_05030	COG0564	pseudouridine synthase activity
XppCFBP6982P_05035	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XppCFBP6982P_05045	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XppCFBP6982P_05045	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
XppCFBP6982P_05060	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
XppCFBP6982P_05065	COG0045	succinate-CoA ligase (ADP-forming) activity
XppCFBP6982P_05110	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
XppCFBP6982P_05115	COG0237	dephospho-CoA kinase activity
XppCFBP6982P_05120	COG3328	transposase activity
XppCFBP6982P_05145	COG0745	RESPONSE REGULATOR receiver
XppCFBP6982P_05155	COG0189	ligase activity
XppCFBP6982P_05185	COG2856	Zn peptidase
XppCFBP6982P_05365	COG2003	Belongs to the UPF0758 family
XppCFBP6982P_05395	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
XppCFBP6982P_05430	COG2022	thiamine diphosphate biosynthetic process
XppCFBP6982P_05440	COG0220	tRNA (guanine-N7-)-methyltransferase activity
XppCFBP6982P_05445	COG0471	metal ion transport
XppCFBP6982P_05445	COG3273	potassium ion transport
XppCFBP6982P_05470	COG1970	mechanosensitive ion channel activity
XppCFBP6982P_05480	COG1609	Transcriptional regulator
XppCFBP6982P_05490	COG3250	beta-galactosidase activity
XppCFBP6982P_05495	COG4948	Mandelate Racemase Muconate Lactonizing
XppCFBP6982P_05505	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
XppCFBP6982P_05515	COG0308	aminopeptidase N
XppCFBP6982P_05520	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XppCFBP6982P_05530	COG0529	Catalyzes the synthesis of activated sulfate
XppCFBP6982P_05530	COG2895	sulfate adenylyltransferase (ATP) activity
XppCFBP6982P_05535	COG0175	sulfate reduction
XppCFBP6982P_05540	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
XppCFBP6982P_05545	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
XppCFBP6982P_05550	COG0175	sulfate reduction
XppCFBP6982P_05590	COG1648	precorrin-2 dehydrogenase activity
XppCFBP6982P_05590	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
XppCFBP6982P_05605	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
XppCFBP6982P_05610	COG3588	fructose-bisphosphate aldolase
XppCFBP6982P_05620	COG0469	pyruvate kinase activity
XppCFBP6982P_05630	COG0126	phosphoglycerate kinase activity
XppCFBP6982P_05665	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
XppCFBP6982P_05675	COG3328	transposase activity
XppCFBP6982P_05685	COG3047	cAMP biosynthetic process
XppCFBP6982P_05700	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XppCFBP6982P_05700	COG3453	Protein conserved in bacteria
XppCFBP6982P_05705	COG0725	ABC transporter, periplasmic molybdate-binding protein
XppCFBP6982P_05710	COG4149	molybdate abc transporter
XppCFBP6982P_05715	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
XppCFBP6982P_05735	COG0642	Histidine kinase
XppCFBP6982P_05740	COG0745	RESPONSE REGULATOR receiver
XppCFBP6982P_05760	COG1022	Amp-dependent synthetase and ligase
XppCFBP6982P_05785	COG1376	ErfK ybiS ycfS ynhG family protein
XppCFBP6982P_05790	COG0739	heme binding
XppCFBP6982P_05795	COG4773	Receptor
XppCFBP6982P_05810	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
XppCFBP6982P_05815	COG1301	dicarboxylic acid transport
XppCFBP6982P_05825	COG2304	oxidoreductase activity
XppCFBP6982P_05845	COG0714	Associated with various cellular activities
XppCFBP6982P_05875	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
XppCFBP6982P_05890	COG0254	rRNA binding
XppCFBP6982P_05895	COG1957	nucleoside hydrolase
XppCFBP6982P_05900	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
XppCFBP6982P_05910	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
XppCFBP6982P_05915	COG1758	RNA polymerase activity
XppCFBP6982P_05925	COG1561	YicC-like family, N-terminal region
XppCFBP6982P_05930	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
XppCFBP6982P_05940	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
XppCFBP6982P_05945	COG0635	Involved in the biosynthesis of porphyrin-containing compound
XppCFBP6982P_05960	COG0006	proline dipeptidase activity
XppCFBP6982P_05970	COG0006	proline dipeptidase activity
XppCFBP6982P_05975	COG3079	Belongs to the UPF0149 family
XppCFBP6982P_05995	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
XppCFBP6982P_06015	COG2912	Transglutaminase-like superfamily
XppCFBP6982P_06025	COG1773	rubredoxin
XppCFBP6982P_06030	COG0352	thiamine-phosphate diphosphorylase activity
XppCFBP6982P_06060	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
XppCFBP6982P_06070	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
XppCFBP6982P_06075	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XppCFBP6982P_06105	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
XppCFBP6982P_06110	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XppCFBP6982P_06115	COG1028	Short-chain dehydrogenase reductase Sdr
XppCFBP6982P_06125	COG0671	phosphoesterase, PA-phosphatase related
XppCFBP6982P_06135	COG3781	membrane
XppCFBP6982P_06145	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
XppCFBP6982P_06150	COG0563	adenylate kinase activity
XppCFBP6982P_06165	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
XppCFBP6982P_06175	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
XppCFBP6982P_06195	COG3710	Transcriptional regulator
XppCFBP6982P_06200	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
XppCFBP6982P_06215	COG0840	transmembrane signaling receptor activity
XppCFBP6982P_06220	COG0405	Gamma-glutamyltransferase
XppCFBP6982P_06225	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
XppCFBP6982P_06245	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
XppCFBP6982P_06250	COG0473	3-isopropylmalate dehydrogenase activity
XppCFBP6982P_06255	COG0066	3-isopropylmalate dehydratase activity
XppCFBP6982P_06260	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
XppCFBP6982P_06280	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
XppCFBP6982P_06285	COG1538	Outer membrane efflux protein
XppCFBP6982P_06290	COG1519	Transferase
XppCFBP6982P_06295	COG1560	Kdo2-lipid A biosynthetic process
XppCFBP6982P_06320	COG0280	phosphate acetyltransferase
XppCFBP6982P_06320	COG0281	malic enzyme
XppCFBP6982P_06325	COG1301	dicarboxylic acid transport
XppCFBP6982P_06350	COG0583	DNA-binding transcription factor activity
XppCFBP6982P_06355	COG0667	Aldo Keto reductase
XppCFBP6982P_06370	COG2197	response regulator
XppCFBP6982P_06380	COG1840	ABC-type Fe3 transport system, periplasmic component
XppCFBP6982P_06385	COG0642	Histidine kinase
XppCFBP6982P_06405	COG2851	Citrate transporter
XppCFBP6982P_06410	COG1028	Short-chain dehydrogenase reductase Sdr
XppCFBP6982P_06415	COG1609	Transcriptional regulator
XppCFBP6982P_06420	COG2211	Major facilitator Superfamily
XppCFBP6982P_06445	COG1162	GTPase activity
XppCFBP6982P_06450	COG0436	Aminotransferase
XppCFBP6982P_06465	COG0726	polysaccharide deacetylase
XppCFBP6982P_06470	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
XppCFBP6982P_06485	COG3964	amidohydrolase
XppCFBP6982P_06490	COG0402	S-adenosylhomocysteine deaminase activity
XppCFBP6982P_06525	COG3328	transposase activity
XppCFBP6982P_06535	COG1307	EDD domain protein, DegV family
XppCFBP6982P_06550	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
XppCFBP6982P_06555	COG3791	Glutathione-dependent formaldehyde-activating
XppCFBP6982P_06580	COG0745	RESPONSE REGULATOR receiver
XppCFBP6982P_06585	COG2205	protein histidine kinase activity
XppCFBP6982P_06615	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
XppCFBP6982P_06625	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
XppCFBP6982P_06630	COG1012	belongs to the aldehyde dehydrogenase family
XppCFBP6982P_06635	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
XppCFBP6982P_06655	COG1183	phosphatidylcholine synthase activity
XppCFBP6982P_06665	COG0442	prolyl-tRNA aminoacylation
XppCFBP6982P_06680	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
XppCFBP6982P_06685	COG1127	ABC transporter
XppCFBP6982P_06690	COG3218	ABC-type transport auxiliary lipoprotein component
XppCFBP6982P_06690	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
XppCFBP6982P_06720	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
XppCFBP6982P_06725	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
XppCFBP6982P_06725	COG0662	Cupin 2, conserved barrel domain protein
XppCFBP6982P_06755	COG2086	electron transfer activity
XppCFBP6982P_06770	COG0546	phosphoglycolate phosphatase activity
XppCFBP6982P_06770	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
XppCFBP6982P_06775	COG0277	FAD linked oxidase domain protein
XppCFBP6982P_06785	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XppCFBP6982P_06805	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XppCFBP6982P_06810	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
XppCFBP6982P_06815	COG0438	transferase activity, transferring glycosyl groups
XppCFBP6982P_06835	COG0438	transferase activity, transferring glycosyl groups
XppCFBP6982P_06845	COG0626	cystathionine gamma-synthase activity
XppCFBP6982P_06875	COG0625	glutathione transferase activity
XppCFBP6982P_06890	COG0513	Belongs to the DEAD box helicase family
XppCFBP6982P_06895	COG0720	synthase
XppCFBP6982P_06905	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
XppCFBP6982P_06915	COG1956	GAF domain-containing protein
XppCFBP6982P_06930	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
XppCFBP6982P_06935	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
XppCFBP6982P_06945	COG4991	sh3 domain protein
XppCFBP6982P_06955	COG0339	signal peptide processing
XppCFBP6982P_06970	COG2132	Multicopper oxidase
XppCFBP6982P_07005	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
XppCFBP6982P_07010	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XppCFBP6982P_07015	COG1136	(ABC) transporter
XppCFBP6982P_07020	COG0577	efflux transmembrane transporter activity
XppCFBP6982P_07020	COG1136	(ABC) transporter
XppCFBP6982P_07035	COG2204	response regulator
XppCFBP6982P_07040	COG4191	Histidine kinase
XppCFBP6982P_07045	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
XppCFBP6982P_07060	COG0355	proton-transporting ATP synthase activity, rotational mechanism
XppCFBP6982P_07065	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
XppCFBP6982P_07070	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
XppCFBP6982P_07075	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
XppCFBP6982P_07080	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
XppCFBP6982P_07085	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
XppCFBP6982P_07095	COG0356	it plays a direct role in the translocation of protons across the membrane
XppCFBP6982P_07115	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XppCFBP6982P_07125	COG0508	dehydrogenase complex catalyzes the overall conversion of
XppCFBP6982P_07165	COG2011	ABC-type metal ion transport system permease component
XppCFBP6982P_07170	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
XppCFBP6982P_07175	COG0697	spore germination
XppCFBP6982P_07180	COG1666	GTP binding
XppCFBP6982P_07190	COG5002	protein histidine kinase activity
XppCFBP6982P_07190	COG2198	Histidine kinase
XppCFBP6982P_07190	COG0784	Response regulator, receiver
XppCFBP6982P_07215	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
XppCFBP6982P_07220	COG1187	pseudouridine synthase activity
XppCFBP6982P_07225	COG2813	Specifically methylates the guanine in position
XppCFBP6982P_07240	COG3039	Transposase
XppCFBP6982P_07270	COG2202	Pas domain
XppCFBP6982P_07270	COG2205	protein histidine kinase activity
XppCFBP6982P_07290	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
XppCFBP6982P_07295	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XppCFBP6982P_07300	COG1522	sequence-specific DNA binding
XppCFBP6982P_07350	COG0842	Transport permease protein
XppCFBP6982P_07355	COG1131	(ABC) transporter
XppCFBP6982P_07360	COG0025	NhaP-type Na H and K H
XppCFBP6982P_07370	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
XppCFBP6982P_07375	COG1573	uracil-dna glycosylase
XppCFBP6982P_07385	COG3384	dioxygenase
XppCFBP6982P_07395	COG0583	DNA-binding transcription factor activity
XppCFBP6982P_07405	COG0667	Aldo Keto reductase
XppCFBP6982P_07420	COG3590	peptidase
XppCFBP6982P_07435	COG0531	amino acid
XppCFBP6982P_07450	COG2972	Histidine kinase
XppCFBP6982P_07470	COG3685	Protein conserved in bacteria
XppCFBP6982P_07475	COG3546	catalase activity
XppCFBP6982P_07525	COG1271	oxidase subunit
XppCFBP6982P_07530	COG1294	oxidase, subunit
XppCFBP6982P_07545	COG1028	Short-chain dehydrogenase reductase Sdr
XppCFBP6982P_07565	COG1063	alcohol dehydrogenase
XppCFBP6982P_07575	COG3328	transposase activity
XppCFBP6982P_07645	COG0251	oxidation-reduction process
XppCFBP6982P_07670	COG0659	secondary active sulfate transmembrane transporter activity
XppCFBP6982P_07675	COG0038	chloride channel
XppCFBP6982P_07685	COG0024	Methionine aminopeptidase
XppCFBP6982P_07720	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
XppCFBP6982P_07725	COG1490	D-aminoacyl-tRNA deacylase activity
XppCFBP6982P_07730	COG1560	Kdo2-lipid A biosynthetic process
XppCFBP6982P_07775	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
XppCFBP6982P_07775	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
XppCFBP6982P_07780	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
XppCFBP6982P_07785	COG0242	peptide deformylase activity
XppCFBP6982P_07790	COG1652	LysM domain
XppCFBP6982P_07795	COG0758	DNA mediated transformation
XppCFBP6982P_07815	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
XppCFBP6982P_07815	COG1754	DNA topoisomerase type I activity
XppCFBP6982P_07820	COG0009	L-threonylcarbamoyladenylate synthase
XppCFBP6982P_07835	COG1028	Short-chain dehydrogenase reductase Sdr
XppCFBP6982P_07850	COG0616	signal peptide processing
XppCFBP6982P_07855	COG0534	Mate efflux family protein
XppCFBP6982P_07875	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
XppCFBP6982P_07880	COG0625	glutathione transferase activity
XppCFBP6982P_07895	COG1252	NADH dehydrogenase
XppCFBP6982P_07900	COG2860	membrane
XppCFBP6982P_07905	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
XppCFBP6982P_07910	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
XppCFBP6982P_07915	COG2201	protein-glutamate methylesterase activity
XppCFBP6982P_07920	COG2177	Part of the ABC transporter FtsEX involved in
XppCFBP6982P_07925	COG2884	Cell division ATP-binding protein ftsE
XppCFBP6982P_07930	COG0513	Belongs to the DEAD box helicase family
XppCFBP6982P_07935	COG3118	belongs to the thioredoxin family
XppCFBP6982P_07940	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
XppCFBP6982P_07950	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
XppCFBP6982P_07975	COG1652	LysM domain
XppCFBP6982P_07980	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
XppCFBP6982P_07980	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
XppCFBP6982P_07985	COG1473	amidohydrolase
XppCFBP6982P_07990	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XppCFBP6982P_07995	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XppCFBP6982P_08015	COG5383	Protein conserved in bacteria
XppCFBP6982P_08055	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
XppCFBP6982P_08060	COG3023	N-Acetylmuramoyl-L-alanine amidase
XppCFBP6982P_08080	COG0531	amino acid
XppCFBP6982P_08100	COG3328	transposase activity
XppCFBP6982P_08105	COG4682	membrane
XppCFBP6982P_08110	COG2133	pyrroloquinoline quinone binding
XppCFBP6982P_08120	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
XppCFBP6982P_08125	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
XppCFBP6982P_08130	COG0828	Belongs to the bacterial ribosomal protein bS21 family
XppCFBP6982P_08135	COG1610	YqeY-like protein
XppCFBP6982P_08145	COG1295	ribonuclease BN
XppCFBP6982P_08150	COG0358	DNA primase activity
XppCFBP6982P_08165	COG0109	protoheme IX farnesyltransferase activity
XppCFBP6982P_08195	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
XppCFBP6982P_08205	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
XppCFBP6982P_08245	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
XppCFBP6982P_08250	COG0739	heme binding
XppCFBP6982P_08255	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
XppCFBP6982P_08265	COG2223	nitrite transmembrane transporter activity
XppCFBP6982P_08270	COG0708	Exodeoxyribonuclease III
XppCFBP6982P_08275	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
XppCFBP6982P_08285	COG1192	Involved in chromosome partitioning
XppCFBP6982P_08290	COG1475	DNA binding
XppCFBP6982P_08305	COG0463	Glycosyl transferase, family 2
XppCFBP6982P_08325	COG0756	dUTP diphosphatase activity
XppCFBP6982P_08330	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
XppCFBP6982P_08335	COG2003	Belongs to the UPF0758 family
XppCFBP6982P_08340	COG0018	arginyl-trna synthetase
XppCFBP6982P_08355	COG4221	oxidoreductase activity
XppCFBP6982P_08360	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
XppCFBP6982P_08360	COG2755	lipolytic protein G-D-S-L family
XppCFBP6982P_08370	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
XppCFBP6982P_08375	COG1166	arginine decarboxylase activity
XppCFBP6982P_08380	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
XppCFBP6982P_08400	COG3291	Pkd domain containing protein
XppCFBP6982P_08400	COG3525	Glycosyl hydrolase, family 20, catalytic domain
XppCFBP6982P_08420	COG0606	chelatase, subunit chli
XppCFBP6982P_08430	COG4943	cyclic-guanylate-specific phosphodiesterase activity
XppCFBP6982P_08460	COG1690	Belongs to the RtcB family
XppCFBP6982P_08500	COG1090	epimerase
XppCFBP6982P_08505	COG0745	RESPONSE REGULATOR receiver
XppCFBP6982P_08510	COG0642	Histidine kinase
XppCFBP6982P_08530	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XppCFBP6982P_08555	COG1011	Hydrolase
XppCFBP6982P_08560	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
XppCFBP6982P_08575	COG0753	catalase activity
XppCFBP6982P_08595	COG2197	response regulator
XppCFBP6982P_08600	COG4585	Histidine kinase
XppCFBP6982P_08605	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XppCFBP6982P_08610	COG1136	(ABC) transporter
XppCFBP6982P_08635	COG0697	spore germination
XppCFBP6982P_08660	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XppCFBP6982P_08665	COG0180	Tryptophanyl-tRNA synthetase
XppCFBP6982P_08670	COG3237	CsbD-like
XppCFBP6982P_08715	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
XppCFBP6982P_08730	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
XppCFBP6982P_08735	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
XppCFBP6982P_08735	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
XppCFBP6982P_08750	COG3228	Belongs to the MtfA family
XppCFBP6982P_08765	COG2205	protein histidine kinase activity
XppCFBP6982P_08770	COG0745	RESPONSE REGULATOR receiver
XppCFBP6982P_08780	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
XppCFBP6982P_08820	COG3328	transposase activity
XppCFBP6982P_08835	COG1199	ATP-dependent helicase activity
XppCFBP6982P_08850	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
XppCFBP6982P_08940	COG4555	ABC transporter
XppCFBP6982P_08950	COG1476	TRANSCRIPTIONal
XppCFBP6982P_08970	COG1230	cation diffusion facilitator family transporter
XppCFBP6982P_08975	COG0633	Ferredoxin
XppCFBP6982P_08975	COG0543	2 iron, 2 sulfur cluster binding
XppCFBP6982P_08980	COG1131	(ABC) transporter
XppCFBP6982P_08985	COG0842	Transport permease protein
XppCFBP6982P_08990	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
XppCFBP6982P_09015	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XppCFBP6982P_09035	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
XppCFBP6982P_09040	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
XppCFBP6982P_09055	COG0045	succinate-CoA ligase (ADP-forming) activity
XppCFBP6982P_09055	COG1042	CoA-binding domain protein
XppCFBP6982P_09055	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
XppCFBP6982P_09060	COG2239	Acts as a magnesium transporter
XppCFBP6982P_09090	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
XppCFBP6982P_09095	COG3387	PFAM Glycoside hydrolase 15-related
XppCFBP6982P_09110	COG3100	YcgL domain-containing protein
XppCFBP6982P_09115	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
XppCFBP6982P_09125	COG0463	Glycosyl transferase, family 2
XppCFBP6982P_09135	COG1028	Short-chain dehydrogenase reductase Sdr
XppCFBP6982P_09175	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
XppCFBP6982P_09190	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
XppCFBP6982P_09240	COG0408	coproporphyrinogen oxidase activity
XppCFBP6982P_09275	COG0515	serine threonine protein kinase
XppCFBP6982P_09280	COG0631	protein serine/threonine phosphatase activity
XppCFBP6982P_09305	COG0667	Aldo Keto reductase
XppCFBP6982P_09310	COG0583	DNA-binding transcription factor activity
XppCFBP6982P_09325	COG3501	Rhs element vgr protein
XppCFBP6982P_09385	COG0154	amidase activity
XppCFBP6982P_09390	COG3039	Transposase
XppCFBP6982P_09415	COG3328	transposase activity
XppCFBP6982P_09500	COG0210	DNA helicase
XppCFBP6982P_09515	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XppCFBP6982P_09520	COG0583	DNA-binding transcription factor activity
XppCFBP6982P_09525	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
XppCFBP6982P_09540	COG2159	amidohydrolase
XppCFBP6982P_09545	COG0267	Belongs to the bacterial ribosomal protein bL33 family
XppCFBP6982P_09550	COG0227	Belongs to the bacterial ribosomal protein bL28 family
XppCFBP6982P_09565	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XppCFBP6982P_09590	COG0357	Ribosomal RNA small subunit methyltransferase G
XppCFBP6982P_09595	COG3540	Alkaline phosphatase
XppCFBP6982P_09605	COG2091	lysine biosynthetic process via aminoadipic acid
XppCFBP6982P_09620	COG0708	Exodeoxyribonuclease III
XppCFBP6982P_09625	COG1846	Transcriptional regulator
XppCFBP6982P_09625	COG1940	carbohydrate kinase activity
XppCFBP6982P_09635	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
XppCFBP6982P_09645	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
XppCFBP6982P_09650	COG3162	membrane
XppCFBP6982P_09660	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
XppCFBP6982P_09690	COG3507	Belongs to the glycosyl hydrolase 43 family
XppCFBP6982P_09710	COG1028	Short-chain dehydrogenase reductase Sdr
XppCFBP6982P_09715	COG0179	Fumarylacetoacetate (FAA) hydrolase
XppCFBP6982P_09720	COG4948	Mandelate Racemase Muconate Lactonizing
XppCFBP6982P_09725	COG3254	rhamnose metabolic process
XppCFBP6982P_09730	COG0738	Major facilitator superfamily
XppCFBP6982P_09735	COG1414	Transcriptional regulator
XppCFBP6982P_09740	COG2207	Transcriptional regulator
XppCFBP6982P_09740	COG1917	Cupin 2, conserved barrel domain protein
XppCFBP6982P_09750	COG1971	Probably functions as a manganese efflux pump
XppCFBP6982P_09755	COG2205	protein histidine kinase activity
XppCFBP6982P_09770	COG3459	Glycosyltransferase 36 associated
XppCFBP6982P_09775	COG2211	Major facilitator Superfamily
XppCFBP6982P_09780	COG3265	gluconokinase activity
XppCFBP6982P_09790	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XppCFBP6982P_09810	COG2911	Protein conserved in bacteria
XppCFBP6982P_09815	COG0729	surface antigen
XppCFBP6982P_09820	COG4771	TonB-dependent receptor
XppCFBP6982P_09830	COG0457	Tetratricopeptide repeat
XppCFBP6982P_09840	COG0752	glycyl-tRNA synthetase alpha subunit
XppCFBP6982P_09845	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
XppCFBP6982P_09860	COG0519	Catalyzes the synthesis of GMP from XMP
XppCFBP6982P_09860	COG0518	GMP synthase (glutamine-hydrolyzing) activity
XppCFBP6982P_09875	COG0805	protein transport
XppCFBP6982P_09880	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
XppCFBP6982P_09885	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
XppCFBP6982P_09895	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
XppCFBP6982P_09915	COG2974	May be involved in recombination
XppCFBP6982P_09920	COG0037	tRNA processing
XppCFBP6982P_09930	COG2115	Belongs to the xylose isomerase family
XppCFBP6982P_09940	COG3661	Belongs to the glycosyl hydrolase 67 family
XppCFBP6982P_09950	COG4948	Mandelate Racemase Muconate Lactonizing
XppCFBP6982P_09960	COG1472	Belongs to the glycosyl hydrolase 3 family
XppCFBP6982P_09965	COG0246	Mannitol dehydrogenase
XppCFBP6982P_10030	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
XppCFBP6982P_10055	COG3386	PFAM SMP-30 Gluconolaconase
XppCFBP6982P_10065	COG3250	beta-galactosidase activity
XppCFBP6982P_10070	COG1904	glucuronate isomerase
XppCFBP6982P_10075	COG3693	PFAM glycoside hydrolase, family 10
XppCFBP6982P_10085	COG3693	PFAM glycoside hydrolase, family 10
XppCFBP6982P_10100	COG2211	Major facilitator Superfamily
XppCFBP6982P_10150	COG3328	transposase activity
XppCFBP6982P_10190	COG2937	Belongs to the GPAT DAPAT family
XppCFBP6982P_10225	COG0284	orotidine-5'-phosphate decarboxylase activity
XppCFBP6982P_10230	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
XppCFBP6982P_10235	COG3132	Protein of unknown function, DUF480
XppCFBP6982P_10245	COG0635	Involved in the biosynthesis of porphyrin-containing compound
XppCFBP6982P_10295	COG0210	DNA helicase
XppCFBP6982P_10300	COG1435	thymidine kinase activity
XppCFBP6982P_10310	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
XppCFBP6982P_10320	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
XppCFBP6982P_10350	COG3135	benzoate transporter
XppCFBP6982P_10380	COG0676	glucose-6-phosphate 1-epimerase activity
XppCFBP6982P_10390	COG3012	SEC-C Motif Domain Protein
XppCFBP6982P_10440	COG3039	Transposase
XppCFBP6982P_10485	COG0730	response to heat
XppCFBP6982P_10495	COG3328	transposase activity
XppCFBP6982P_10510	COG0302	gtp cyclohydrolase
XppCFBP6982P_10525	COG1566	PFAM secretion protein HlyD family protein
XppCFBP6982P_10535	COG1289	transmembrane transporter activity
XppCFBP6982P_10540	COG0477	Major facilitator Superfamily
XppCFBP6982P_10550	COG0583	DNA-binding transcription factor activity
XppCFBP6982P_10555	COG4221	oxidoreductase activity
XppCFBP6982P_10565	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XppCFBP6982P_10590	COG3328	transposase activity
XppCFBP6982P_10615	COG0564	pseudouridine synthase activity
XppCFBP6982P_10715	COG4790	Type iii secretion
XppCFBP6982P_10735	COG1157	protein secretion by the type III secretion system
XppCFBP6982P_10745	COG4789	Type iii secretion
XppCFBP6982P_10865	COG3039	Transposase
XppCFBP6982P_10955	COG0439	Biotin carboxylase
XppCFBP6982P_11045	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
XppCFBP6982P_11050	COG1074	ATP-dependent DNA helicase activity
XppCFBP6982P_11055	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
XppCFBP6982P_11090	COG1127	ABC transporter
XppCFBP6982P_11095	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
XppCFBP6982P_11100	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
XppCFBP6982P_11115	COG2853	Lipoprotein
XppCFBP6982P_11130	COG0386	Belongs to the glutathione peroxidase family
XppCFBP6982P_11140	COG1322	Protein conserved in bacteria
XppCFBP6982P_11150	COG0583	DNA-binding transcription factor activity
XppCFBP6982P_11170	COG0531	amino acid
XppCFBP6982P_11175	COG3537	Alpha-1,2-mannosidase
XppCFBP6982P_11190	COG2203	Gaf domain
XppCFBP6982P_11190	COG2199	diguanylate cyclase activity
XppCFBP6982P_11195	COG3835	regulator
XppCFBP6982P_11200	COG1929	Belongs to the glycerate kinase type-1 family
XppCFBP6982P_11220	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
XppCFBP6982P_11230	COG0861	Integral membrane protein TerC family
XppCFBP6982P_11255	COG0584	glycerophosphoryl diester phosphodiesterase
XppCFBP6982P_11270	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
XppCFBP6982P_11275	COG0726	polysaccharide deacetylase
XppCFBP6982P_11285	COG0706	membrane insertase activity
XppCFBP6982P_11290	COG0594	ribonuclease P activity
XppCFBP6982P_11295	COG0230	Belongs to the bacterial ribosomal protein bL34 family
XppCFBP6982P_11315	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
XppCFBP6982P_11320	COG0187	DNA topoisomerase II activity
XppCFBP6982P_11330	COG0501	Belongs to the peptidase M48B family
XppCFBP6982P_11375	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
XppCFBP6982P_11430	COG0793	Belongs to the peptidase S41A family
XppCFBP6982P_11435	COG4942	peptidase
XppCFBP6982P_11445	COG2234	aminopeptidase activity
XppCFBP6982P_11455	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XppCFBP6982P_11460	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XppCFBP6982P_11470	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XppCFBP6982P_11480	COG1064	alcohol dehydrogenase
XppCFBP6982P_11495	COG0493	'glutamate synthase
XppCFBP6982P_11500	COG0069	glutamate synthase activity
XppCFBP6982P_11500	COG0070	glutamate synthase
XppCFBP6982P_11500	COG0067	glutamate synthase
XppCFBP6982P_11595	COG1205	dead DEAH box helicase
XppCFBP6982P_11595	COG1111	helicase
XppCFBP6982P_11600	COG1272	protein, Hemolysin III
XppCFBP6982P_11620	COG0300	oxidoreductase activity
XppCFBP6982P_11625	COG1028	Short-chain dehydrogenase reductase Sdr
XppCFBP6982P_11655	COG2249	NAD(P)H dehydrogenase (quinone) activity
XppCFBP6982P_11665	COG3039	Transposase
XppCFBP6982P_11680	COG3039	Transposase
XppCFBP6982P_11685	COG3237	CsbD-like
XppCFBP6982P_11730	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XppCFBP6982P_11780	COG0714	Associated with various cellular activities
XppCFBP6982P_11825	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
XppCFBP6982P_11835	COG4772	TonB-dependent receptor
XppCFBP6982P_11865	COG1304	FMN binding
XppCFBP6982P_11870	COG1755	Isoprenylcysteine carboxyl methyltransferase
XppCFBP6982P_11875	COG4585	Histidine kinase
XppCFBP6982P_11880	COG2197	response regulator
XppCFBP6982P_11910	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
XppCFBP6982P_11965	COG3328	transposase activity
XppCFBP6982P_11985	COG3039	Transposase
XppCFBP6982P_12000	COG0366	Alpha amylase catalytic
XppCFBP6982P_12005	COG0366	Alpha amylase catalytic
XppCFBP6982P_12010	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
XppCFBP6982P_12030	COG2755	lipolytic protein G-D-S-L family
XppCFBP6982P_12030	COG0657	acetylesterase activity
XppCFBP6982P_12040	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
XppCFBP6982P_12055	COG3507	Belongs to the glycosyl hydrolase 43 family
XppCFBP6982P_12060	COG1609	Transcriptional regulator
XppCFBP6982P_12070	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
XppCFBP6982P_12075	COG1028	Short-chain dehydrogenase reductase Sdr
XppCFBP6982P_12085	COG2755	lipolytic protein G-D-S-L family
XppCFBP6982P_12095	COG3186	Phenylalanine-4-hydroxylase
XppCFBP6982P_12100	COG1522	sequence-specific DNA binding
XppCFBP6982P_12110	COG1752	Esterase of the alpha-beta hydrolase superfamily
XppCFBP6982P_12120	COG1119	ATPase activity
XppCFBP6982P_12135	COG0517	IMP dehydrogenase activity
XppCFBP6982P_12135	COG1125	glycine betaine transport
XppCFBP6982P_12150	COG1262	PFAM Formylglycine-generating sulfatase enzyme
XppCFBP6982P_12180	COG0489	protein tyrosine kinase activity
XppCFBP6982P_12185	COG2062	phosphohistidine phosphatase, SixA
XppCFBP6982P_12195	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XppCFBP6982P_12240	COG1968	undecaprenyl-diphosphatase activity
XppCFBP6982P_12250	COG0174	glutamine synthetase
XppCFBP6982P_12255	COG0347	Belongs to the P(II) protein family
XppCFBP6982P_12260	COG0004	ammonium transporteR
XppCFBP6982P_12265	COG3852	Histidine kinase
XppCFBP6982P_12270	COG2204	response regulator
XppCFBP6982P_12275	COG2032	superoxide dismutase activity
XppCFBP6982P_12280	COG2032	superoxide dismutase activity
XppCFBP6982P_12295	COG0183	Belongs to the thiolase family
XppCFBP6982P_12330	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
XppCFBP6982P_12335	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
XppCFBP6982P_12340	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
XppCFBP6982P_12365	COG2205	protein histidine kinase activity
XppCFBP6982P_12390	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
XppCFBP6982P_12405	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XppCFBP6982P_12410	COG3177	Filamentation induced by cAMP protein fic
XppCFBP6982P_12415	COG0596	Alpha beta hydrolase
XppCFBP6982P_12425	COG0318	PFAM AMP-dependent synthetase and ligase
XppCFBP6982P_12430	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XppCFBP6982P_12445	COG1181	Belongs to the D-alanine--D-alanine ligase family
XppCFBP6982P_12460	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
XppCFBP6982P_12470	COG0564	pseudouridine synthase activity
XppCFBP6982P_12490	COG1446	asparaginase
XppCFBP6982P_12495	COG0339	signal peptide processing
XppCFBP6982P_12530	COG0475	glutathione-regulated potassium exporter activity
XppCFBP6982P_12535	COG0583	DNA-binding transcription factor activity
XppCFBP6982P_12540	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
XppCFBP6982P_12545	COG2224	Isocitrate lyase
XppCFBP6982P_12550	COG3706	GGDEF domain
XppCFBP6982P_12565	COG3039	Transposase
XppCFBP6982P_12590	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
XppCFBP6982P_12595	COG1960	acyl-CoA dehydrogenase activity
XppCFBP6982P_12665	COG0697	spore germination
XppCFBP6982P_12675	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
XppCFBP6982P_12680	COG1846	Transcriptional regulator
XppCFBP6982P_12685	COG1764	response to oxidative stress
XppCFBP6982P_12705	COG2130	NADP-dependent
XppCFBP6982P_12720	COG1187	pseudouridine synthase activity
XppCFBP6982P_12730	COG1643	Atp-dependent helicase
XppCFBP6982P_12745	COG4807	Protein conserved in bacteria
XppCFBP6982P_12750	COG2351	hydroxyisourate hydrolase activity
XppCFBP6982P_12755	COG2072	flavoprotein involved in K transport
XppCFBP6982P_12775	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
XppCFBP6982P_12785	COG0583	DNA-binding transcription factor activity
XppCFBP6982P_12825	COG2252	PERMEase
XppCFBP6982P_12850	COG0084	hydrolase, TatD family'
XppCFBP6982P_12865	COG0583	DNA-binding transcription factor activity
XppCFBP6982P_12870	COG2814	Major facilitator Superfamily
XppCFBP6982P_12885	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
XppCFBP6982P_12890	COG1902	pentaerythritol trinitrate reductase activity
XppCFBP6982P_12910	COG0745	RESPONSE REGULATOR receiver
XppCFBP6982P_12915	COG2205	protein histidine kinase activity
XppCFBP6982P_12920	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XppCFBP6982P_12945	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
XppCFBP6982P_12950	COG0583	DNA-binding transcription factor activity
XppCFBP6982P_12965	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
XppCFBP6982P_12990	COG0702	epimerase
XppCFBP6982P_12995	COG1733	regulation of RNA biosynthetic process
XppCFBP6982P_13040	COG0129	dihydroxy-acid dehydratase activity
XppCFBP6982P_13055	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
XppCFBP6982P_13110	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
XppCFBP6982P_13115	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
XppCFBP6982P_13140	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
XppCFBP6982P_13155	COG3485	protocatechuate 3,4-dioxygenase
XppCFBP6982P_13160	COG3485	protocatechuate 3,4-dioxygenase
XppCFBP6982P_13170	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XppCFBP6982P_13175	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
XppCFBP6982P_13185	COG1414	Transcriptional regulator
XppCFBP6982P_13205	COG0445	tRNA wobble uridine modification
XppCFBP6982P_13250	COG2267	carboxylic ester hydrolase activity
XppCFBP6982P_13260	COG0156	8-amino-7-oxononanoate synthase activity
XppCFBP6982P_13265	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
XppCFBP6982P_13270	COG1040	competence protein
XppCFBP6982P_13275	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
XppCFBP6982P_13300	COG3039	Transposase
XppCFBP6982P_13365	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
XppCFBP6982P_13440	COG1511	domain protein
XppCFBP6982P_13440	COG3264	Mechanosensitive ion channel
XppCFBP6982P_13445	COG1368	sulfuric ester hydrolase activity
XppCFBP6982P_13450	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
XppCFBP6982P_13455	COG2354	Protein conserved in bacteria
XppCFBP6982P_13460	COG0745	RESPONSE REGULATOR receiver
XppCFBP6982P_13460	COG3706	GGDEF domain
XppCFBP6982P_13465	COG0297	glycogen (starch) synthase activity
XppCFBP6982P_13470	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
XppCFBP6982P_13475	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
XppCFBP6982P_13500	COG0702	epimerase
XppCFBP6982P_13520	COG3328	transposase activity
XppCFBP6982P_13530	COG3039	Transposase
XppCFBP6982P_13535	COG1028	Short-chain dehydrogenase reductase Sdr
XppCFBP6982P_13570	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XppCFBP6982P_13575	COG1028	Short-chain dehydrogenase reductase Sdr
XppCFBP6982P_13585	COG0513	Belongs to the DEAD box helicase family
XppCFBP6982P_13590	COG0508	dehydrogenase complex catalyzes the overall conversion of
XppCFBP6982P_13605	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
XppCFBP6982P_13615	COG3483	tryptophan 2,3-dioxygenase activity
XppCFBP6982P_13620	COG3104	oligopeptide transport
XppCFBP6982P_13640	COG2852	Protein conserved in bacteria
XppCFBP6982P_13645	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
XppCFBP6982P_13665	COG1320	monovalent cation:proton antiporter activity
XppCFBP6982P_13670	COG2212	antiporter activity
XppCFBP6982P_13680	COG0651	ATP synthesis coupled electron transport
XppCFBP6982P_13685	COG1006	Multisubunit Na H antiporter MnhC subunit
XppCFBP6982P_13690	COG2111	Na H antiporter
XppCFBP6982P_13690	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
XppCFBP6982P_13710	COG3179	chitinase
XppCFBP6982P_13730	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
XppCFBP6982P_13735	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
XppCFBP6982P_13755	COG1597	lipid kinase activity
XppCFBP6982P_13780	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
XppCFBP6982P_13785	COG0134	indole-3-glycerol-phosphate synthase activity
XppCFBP6982P_13795	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XppCFBP6982P_13800	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
XppCFBP6982P_13810	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
XppCFBP6982P_13815	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
XppCFBP6982P_13820	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
XppCFBP6982P_13835	COG1051	belongs to the nudix hydrolase family
XppCFBP6982P_13875	COG0316	Belongs to the HesB IscA family
XppCFBP6982P_13895	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
XppCFBP6982P_13910	COG2814	Major facilitator Superfamily
XppCFBP6982P_13920	COG2814	Major facilitator Superfamily
XppCFBP6982P_13925	COG1289	transmembrane transporter activity
XppCFBP6982P_13935	COG0151	Belongs to the GarS family
XppCFBP6982P_13945	COG0138	bifunctional purine biosynthesis protein purh
XppCFBP6982P_13950	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
XppCFBP6982P_13955	COG2267	carboxylic ester hydrolase activity
XppCFBP6982P_13960	COG0671	phosphoesterase, PA-phosphatase related
XppCFBP6982P_13960	COG2453	phosphatase
XppCFBP6982P_13985	COG4589	Belongs to the CDS family
XppCFBP6982P_13990	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
XppCFBP6982P_14015	COG2264	protein methyltransferase activity
XppCFBP6982P_14035	COG0439	Biotin carboxylase
XppCFBP6982P_14045	COG0511	ligase activity, forming carbon-carbon bonds
XppCFBP6982P_14050	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
XppCFBP6982P_14060	COG1324	tolerance protein
XppCFBP6982P_14075	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
XppCFBP6982P_14080	COG0459	protein refolding
XppCFBP6982P_14095	COG3550	peptidyl-serine autophosphorylation
XppCFBP6982P_14100	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
XppCFBP6982P_14115	COG3386	PFAM SMP-30 Gluconolaconase
XppCFBP6982P_14125	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
XppCFBP6982P_14130	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
XppCFBP6982P_14150	COG3039	Transposase
XppCFBP6982P_14170	COG0778	Nitroreductase
XppCFBP6982P_14175	COG2353	YceI-like domain
XppCFBP6982P_14210	COG3052	prosthetic group binding
XppCFBP6982P_14230	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
XppCFBP6982P_14235	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
XppCFBP6982P_14245	COG1802	Transcriptional regulator
XppCFBP6982P_14295	COG3328	transposase activity
XppCFBP6982P_14305	COG4221	oxidoreductase activity
XppCFBP6982P_14335	COG4221	oxidoreductase activity
XppCFBP6982P_14345	COG0435	Glutathione S-transferase
XppCFBP6982P_14410	COG3706	GGDEF domain
XppCFBP6982P_14415	COG1959	2 iron, 2 sulfur cluster binding
XppCFBP6982P_14440	COG0697	spore germination
XppCFBP6982P_14445	COG4305	rare lipoprotein A
XppCFBP6982P_14450	COG5297	Belongs to the glycosyl hydrolase family 6
XppCFBP6982P_14460	COG1113	amino acid transport
XppCFBP6982P_14470	COG0598	Magnesium transport protein CorA
XppCFBP6982P_14485	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
XppCFBP6982P_14515	COG5002	protein histidine kinase activity
XppCFBP6982P_14515	COG5001	Diguanylate cyclase
XppCFBP6982P_14515	COG3447	MASE1 domain protein
XppCFBP6982P_14530	COG2205	protein histidine kinase activity
XppCFBP6982P_14530	COG0784	Response regulator, receiver
XppCFBP6982P_14570	COG2943	transferase activity, transferring hexosyl groups
XppCFBP6982P_14580	COG3275	phosphorelay sensor kinase activity
XppCFBP6982P_14590	COG0181	hydroxymethylbilane synthase activity
XppCFBP6982P_14630	COG1505	serine-type exopeptidase activity
XppCFBP6982P_14650	COG2832	Protein of unknown function (DUF454)
XppCFBP6982P_14660	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
XppCFBP6982P_14670	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
XppCFBP6982P_14675	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
XppCFBP6982P_14680	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
XppCFBP6982P_14710	COG2226	methyltransferase
XppCFBP6982P_14715	COG5001	Diguanylate cyclase
XppCFBP6982P_14715	COG3300	MHYT domain
XppCFBP6982P_14720	COG0308	aminopeptidase N
XppCFBP6982P_14770	COG3284	Transcriptional regulator
XppCFBP6982P_14790	COG1077	Cell shape determining protein MreB Mrl
XppCFBP6982P_14795	COG1792	Involved in formation and maintenance of cell shape
XppCFBP6982P_14810	COG0772	Belongs to the SEDS family
XppCFBP6982P_14825	COG3039	Transposase
XppCFBP6982P_14830	COG3039	Transposase
XppCFBP6982P_14860	COG2951	lytic endotransglycosylase activity
XppCFBP6982P_14865	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
XppCFBP6982P_14870	COG1686	Belongs to the peptidase S11 family
XppCFBP6982P_14880	COG2921	Belongs to the UPF0250 family
XppCFBP6982P_14885	COG0321	lipoyl(octanoyl) transferase activity
XppCFBP6982P_14890	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
XppCFBP6982P_14915	COG1051	belongs to the nudix hydrolase family
XppCFBP6982P_14915	COG1056	cytidyltransferase-related domain
XppCFBP6982P_14950	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
XppCFBP6982P_14955	COG0673	inositol 2-dehydrogenase activity
XppCFBP6982P_14960	COG2823	Periplasmic or secreted lipoprotein
XppCFBP6982P_14965	COG4251	negative regulation of phosphorylation
XppCFBP6982P_14970	COG0784	Response regulator, receiver
XppCFBP6982P_14975	COG4191	Histidine kinase
XppCFBP6982P_14980	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
XppCFBP6982P_15035	COG1459	type II secretion system
XppCFBP6982P_15090	COG1609	Transcriptional regulator
XppCFBP6982P_15095	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
XppCFBP6982P_15100	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
XppCFBP6982P_15110	COG0617	tRNA 3'-terminal CCA addition
XppCFBP6982P_15130	COG0525	valine-tRNA ligase activity
XppCFBP6982P_15145	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
XppCFBP6982P_15155	COG0795	lipopolysaccharide-transporting ATPase activity
XppCFBP6982P_15170	COG4974	Belongs to the 'phage' integrase family
XppCFBP6982P_15185	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
XppCFBP6982P_15195	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
XppCFBP6982P_15195	COG0047	phosphoribosylformylglycinamidine synthase activity
XppCFBP6982P_15200	COG5295	Hep Hag repeat protein
XppCFBP6982P_15205	COG1404	Belongs to the peptidase S8 family
XppCFBP6982P_15210	COG5295	Hep Hag repeat protein
XppCFBP6982P_15215	COG1404	Belongs to the peptidase S8 family
XppCFBP6982P_15220	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
XppCFBP6982P_15230	COG1459	type II secretion system
XppCFBP6982P_15235	COG2165	general secretion pathway protein
XppCFBP6982P_15240	COG4970	Tfp pilus assembly protein FimT
XppCFBP6982P_15245	COG2165	general secretion pathway protein
XppCFBP6982P_15250	COG4795	General secretion pathway protein
XppCFBP6982P_15255	COG3156	type II secretion system protein K
XppCFBP6982P_15260	COG3166	PFAM Fimbrial assembly family protein
XppCFBP6982P_15275	COG1450	Type ii and iii secretion system protein
XppCFBP6982P_15285	COG2188	Transcriptional regulator
XppCFBP6982P_15365	COG1215	transferase activity, transferring glycosyl groups
XppCFBP6982P_15370	COG1215	transferase activity, transferring glycosyl groups
XppCFBP6982P_15375	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
XppCFBP6982P_15405	COG0242	peptide deformylase activity
XppCFBP6982P_15410	COG0488	(ABC) transporter
XppCFBP6982P_15420	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
XppCFBP6982P_15425	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
XppCFBP6982P_15435	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
XppCFBP6982P_15435	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
XppCFBP6982P_15455	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
XppCFBP6982P_15460	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
XppCFBP6982P_15465	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
XppCFBP6982P_15485	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
XppCFBP6982P_15490	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
XppCFBP6982P_15500	COG2205	protein histidine kinase activity
XppCFBP6982P_15505	COG0745	RESPONSE REGULATOR receiver
XppCFBP6982P_15515	COG0277	FAD linked oxidase domain protein
XppCFBP6982P_15520	COG1988	membrane-bound metal-dependent
XppCFBP6982P_15525	COG0792	nuclease activity
XppCFBP6982P_15560	COG2001	Belongs to the MraZ family
XppCFBP6982P_15570	COG3116	cell division
XppCFBP6982P_15580	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
XppCFBP6982P_15585	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
XppCFBP6982P_15590	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
XppCFBP6982P_15600	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
XppCFBP6982P_15605	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
XppCFBP6982P_15610	COG1181	Belongs to the D-alanine--D-alanine ligase family
XppCFBP6982P_15615	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
XppCFBP6982P_15630	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
XppCFBP6982P_15640	COG0739	heme binding
XppCFBP6982P_15645	COG0653	protein targeting
XppCFBP6982P_15650	COG0494	nUDIX hydrolase
XppCFBP6982P_15660	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
XppCFBP6982P_15670	COG1028	Short-chain dehydrogenase reductase Sdr
XppCFBP6982P_15670	COG0604	alcohol dehydrogenase
XppCFBP6982P_15670	COG3321	synthase
XppCFBP6982P_15685	COG0366	Alpha amylase catalytic
XppCFBP6982P_15715	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
XppCFBP6982P_15720	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
XppCFBP6982P_15730	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
XppCFBP6982P_15770	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
XppCFBP6982P_15780	COG4106	trans-aconitate 2-methyltransferase activity
XppCFBP6982P_15785	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
XppCFBP6982P_15800	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XppCFBP6982P_15805	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
XppCFBP6982P_15810	COG0667	Aldo Keto reductase
XppCFBP6982P_15820	COG4771	TonB-dependent receptor
XppCFBP6982P_15840	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XppCFBP6982P_15845	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
XppCFBP6982P_15855	COG2175	clavaminate synthase activity
XppCFBP6982P_15865	COG4181	ATPase activity
XppCFBP6982P_15880	COG0642	Histidine kinase
XppCFBP6982P_15890	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
XppCFBP6982P_15900	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
XppCFBP6982P_15910	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
XppCFBP6982P_15915	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
XppCFBP6982P_15930	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
XppCFBP6982P_15935	COG2967	ApaG domain
XppCFBP6982P_15945	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
XppCFBP6982P_15950	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
XppCFBP6982P_15955	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
XppCFBP6982P_15970	COG0123	including yeast histone deacetylase and acetoin utilization protein
XppCFBP6982P_15975	COG2096	Adenosyltransferase
XppCFBP6982P_15990	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XppCFBP6982P_15995	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XppCFBP6982P_16025	COG3384	dioxygenase
XppCFBP6982P_16030	COG0583	DNA-binding transcription factor activity
XppCFBP6982P_16035	COG0318	PFAM AMP-dependent synthetase and ligase
XppCFBP6982P_16045	COG1024	Enoyl-CoA hydratase
XppCFBP6982P_16065	COG3386	PFAM SMP-30 Gluconolaconase
XppCFBP6982P_16075	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
XppCFBP6982P_16095	COG0697	spore germination
XppCFBP6982P_16105	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
XppCFBP6982P_16120	COG0745	RESPONSE REGULATOR receiver
XppCFBP6982P_16120	COG3706	GGDEF domain
XppCFBP6982P_16130	COG2197	response regulator
XppCFBP6982P_16140	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
XppCFBP6982P_16155	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
XppCFBP6982P_16160	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XppCFBP6982P_16170	COG0583	DNA-binding transcription factor activity
XppCFBP6982P_16175	COG3634	alkyl hydroperoxide reductase activity
XppCFBP6982P_16185	COG2890	protein-(glutamine-N5) methyltransferase activity
XppCFBP6982P_16205	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
XppCFBP6982P_16205	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
XppCFBP6982P_16245	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
XppCFBP6982P_16265	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
XppCFBP6982P_16270	COG1404	Belongs to the peptidase S8 family
XppCFBP6982P_16275	COG1404	Belongs to the peptidase S8 family
XppCFBP6982P_16280	COG1404	Belongs to the peptidase S8 family
XppCFBP6982P_16285	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
XppCFBP6982P_16310	COG1295	ribonuclease BN
XppCFBP6982P_16315	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XppCFBP6982P_16320	COG1254	Belongs to the acylphosphatase family
XppCFBP6982P_16335	COG0521	Mo-molybdopterin cofactor biosynthetic process
XppCFBP6982P_16345	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
XppCFBP6982P_16350	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
XppCFBP6982P_16360	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
XppCFBP6982P_16365	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
XppCFBP6982P_16375	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
XppCFBP6982P_16380	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
XppCFBP6982P_16385	COG0193	aminoacyl-tRNA hydrolase activity
XppCFBP6982P_16390	COG0012	GTP binding
XppCFBP6982P_16410	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
XppCFBP6982P_16420	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
XppCFBP6982P_16425	COG0250	Participates in transcription elongation, termination and antitermination
XppCFBP6982P_16430	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
XppCFBP6982P_16435	COG0081	regulation of translation
XppCFBP6982P_16440	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
XppCFBP6982P_16450	COG0085	RNA polymerase activity
XppCFBP6982P_16455	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
XppCFBP6982P_16460	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
XppCFBP6982P_16465	COG0049	tRNA binding
XppCFBP6982P_16470	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
XppCFBP6982P_16475	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
XppCFBP6982P_16490	COG3328	transposase activity
XppCFBP6982P_16495	COG0051	transcription antitermination factor activity, RNA binding
XppCFBP6982P_16500	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
XppCFBP6982P_16505	COG0088	Forms part of the polypeptide exit tunnel
XppCFBP6982P_16510	COG0089	rRNA binding
XppCFBP6982P_16515	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
XppCFBP6982P_16520	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
XppCFBP6982P_16525	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
XppCFBP6982P_16530	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
XppCFBP6982P_16535	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
XppCFBP6982P_16540	COG0255	Belongs to the universal ribosomal protein uL29 family
XppCFBP6982P_16545	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
XppCFBP6982P_16550	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
XppCFBP6982P_16555	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
XppCFBP6982P_16560	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
XppCFBP6982P_16565	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
XppCFBP6982P_16570	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
XppCFBP6982P_16575	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
XppCFBP6982P_16580	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
XppCFBP6982P_16585	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
XppCFBP6982P_16590	COG1841	ribosomal large subunit assembly
XppCFBP6982P_16595	COG0200	Binds to the 23S rRNA
XppCFBP6982P_16600	COG0201	protein transport
XppCFBP6982P_16605	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
XppCFBP6982P_16610	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
XppCFBP6982P_16615	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
XppCFBP6982P_16620	COG0202	RNA polymerase activity
XppCFBP6982P_16625	COG0203	ribosomal protein L17
XppCFBP6982P_16630	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
XppCFBP6982P_16650	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
XppCFBP6982P_16660	COG0154	amidase activity
XppCFBP6982P_16675	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
XppCFBP6982P_16680	COG0039	L-malate dehydrogenase activity
XppCFBP6982P_16685	COG0625	glutathione transferase activity
XppCFBP6982P_16705	COG0446	pyridine nucleotide-disulphide oxidoreductase
XppCFBP6982P_16705	COG1902	pentaerythritol trinitrate reductase activity
XppCFBP6982P_16710	COG0604	alcohol dehydrogenase
XppCFBP6982P_16720	COG3039	Transposase
XppCFBP6982P_16725	COG2885	chlorophyll binding
XppCFBP6982P_16745	COG0156	8-amino-7-oxononanoate synthase activity
XppCFBP6982P_16750	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
XppCFBP6982P_16755	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
XppCFBP6982P_16760	COG4208	sulfate ABC transporter
XppCFBP6982P_16765	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
XppCFBP6982P_16775	COG1063	alcohol dehydrogenase
XppCFBP6982P_16795	COG0406	alpha-ribazole phosphatase activity
XppCFBP6982P_16805	COG0285	dihydrofolate synthase activity
XppCFBP6982P_16825	COG2833	Protein of unknown function (DUF455)
XppCFBP6982P_16845	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XppCFBP6982P_16850	COG0671	phosphoesterase, PA-phosphatase related
XppCFBP6982P_16855	COG0438	transferase activity, transferring glycosyl groups
XppCFBP6982P_16865	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
XppCFBP6982P_16880	COG4783	chaperone-mediated protein folding
XppCFBP6982P_16895	COG0473	3-isopropylmalate dehydrogenase activity
XppCFBP6982P_16935	COG3328	transposase activity
XppCFBP6982P_16950	COG0544	peptidyl-prolyl cis-trans isomerase activity
XppCFBP6982P_16955	COG0740	serine-type endopeptidase activity
XppCFBP6982P_16960	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
XppCFBP6982P_16990	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
XppCFBP6982P_17000	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XppCFBP6982P_17010	COG0328	RNA-DNA hybrid ribonuclease activity
XppCFBP6982P_17015	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
XppCFBP6982P_17020	COG0631	protein serine/threonine phosphatase activity
XppCFBP6982P_17045	COG0859	PFAM glycosyl transferase family 9
XppCFBP6982P_17050	COG3642	lipopolysaccharide core region biosynthetic process
XppCFBP6982P_17055	COG1234	tRNA 3'-trailer cleavage
XppCFBP6982P_17060	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
XppCFBP6982P_17070	COG0315	cyclic pyranopterin monophosphate synthase activity
XppCFBP6982P_17075	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
XppCFBP6982P_17080	COG0314	molybdopterin synthase activity
XppCFBP6982P_17100	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
XppCFBP6982P_17105	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
XppCFBP6982P_17110	COG0537	adenosine 5'-monophosphoramidase activity
XppCFBP6982P_17130	COG0714	Associated with various cellular activities
XppCFBP6982P_17145	COG0424	maF-like protein
XppCFBP6982P_17150	COG1399	metal-binding, possibly nucleic acid-binding protein
XppCFBP6982P_17155	COG0333	Belongs to the bacterial ribosomal protein bL32 family
XppCFBP6982P_17160	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XppCFBP6982P_17175	COG1028	Short-chain dehydrogenase reductase Sdr
XppCFBP6982P_17180	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
XppCFBP6982P_17190	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
XppCFBP6982P_17195	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
XppCFBP6982P_17230	COG3829	transcription factor binding
XppCFBP6982P_17280	COG2373	Large extracellular alpha-helical protein
XppCFBP6982P_17300	COG3852	Histidine kinase
XppCFBP6982P_17305	COG4953	penicillin-binding protein 1C
XppCFBP6982P_17315	COG0678	peroxiredoxin activity
XppCFBP6982P_17335	COG0330	HflC and HflK could
XppCFBP6982P_17340	COG0330	HflC and HflK could
XppCFBP6982P_17350	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
XppCFBP6982P_17355	COG0308	aminopeptidase N
XppCFBP6982P_17365	COG1028	Short-chain dehydrogenase reductase Sdr
XppCFBP6982P_17370	COG1309	transcriptional regulator
XppCFBP6982P_17430	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
XppCFBP6982P_17440	COG3387	PFAM Glycoside hydrolase 15-related
XppCFBP6982P_17445	COG1028	Short-chain dehydrogenase reductase Sdr
XppCFBP6982P_17455	COG3537	Alpha-1,2-mannosidase
XppCFBP6982P_17475	COG0492	ferredoxin-NADP+ reductase activity
XppCFBP6982P_17505	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XppCFBP6982P_17510	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
XppCFBP6982P_17515	COG2080	2 iron, 2 sulfur cluster binding
XppCFBP6982P_17550	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
XppCFBP6982P_17565	COG0587	DNA-directed DNA polymerase activity
XppCFBP6982P_17585	COG1297	OPT oligopeptide transporter protein
XppCFBP6982P_17605	COG1506	peptidase
XppCFBP6982P_17605	COG0823	Involved in the tonB-independent uptake of proteins
XppCFBP6982P_17635	COG1917	Cupin 2, conserved barrel domain protein
XppCFBP6982P_17635	COG2207	Transcriptional regulator
XppCFBP6982P_17640	COG3328	transposase activity
XppCFBP6982P_17645	COG0753	catalase activity
XppCFBP6982P_17650	COG0656	L-ascorbic acid biosynthetic process
XppCFBP6982P_17660	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
XppCFBP6982P_17660	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
XppCFBP6982P_17685	COG2814	Major facilitator Superfamily
XppCFBP6982P_17705	COG2963	transposase activity
XppCFBP6982P_17715	COG2194	sulfuric ester hydrolase activity
XppCFBP6982P_17730	COG0745	RESPONSE REGULATOR receiver
XppCFBP6982P_17735	COG0642	Histidine kinase
XppCFBP6982P_17745	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
XppCFBP6982P_17750	COG2894	cell division
XppCFBP6982P_17755	COG0850	regulation of cytokinetic process
XppCFBP6982P_17770	COG4585	Histidine kinase
XppCFBP6982P_17775	COG2197	response regulator
XppCFBP6982P_17790	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
XppCFBP6982P_17815	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
XppCFBP6982P_17825	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
XppCFBP6982P_17840	COG1595	DNA-templated transcription, initiation
XppCFBP6982P_17850	COG1946	Acyl-CoA thioesterase
XppCFBP6982P_17865	COG0824	Thioesterase
XppCFBP6982P_17870	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
XppCFBP6982P_17875	COG0261	This protein binds to 23S rRNA in the presence of protein L20
XppCFBP6982P_17880	COG0211	Belongs to the bacterial ribosomal protein bL27 family
XppCFBP6982P_17885	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
XppCFBP6982P_17890	COG0268	Binds directly to 16S ribosomal RNA
XppCFBP6982P_17900	COG0196	riboflavin kinase activity
XppCFBP6982P_17905	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
XppCFBP6982P_17910	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
XppCFBP6982P_17915	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
XppCFBP6982P_17930	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
XppCFBP6982P_17935	COG1845	cytochrome c oxidase, subunit III
XppCFBP6982P_17940	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
XppCFBP6982P_17955	COG3152	Membrane
XppCFBP6982P_17965	COG2207	Transcriptional regulator
XppCFBP6982P_17970	COG0326	Molecular chaperone. Has ATPase activity
XppCFBP6982P_17980	COG1366	Belongs to the anti-sigma-factor antagonist family
XppCFBP6982P_17985	COG1366	Belongs to the anti-sigma-factor antagonist family
XppCFBP6982P_18015	COG4771	TonB-dependent receptor
XppCFBP6982P_18025	COG5507	3-demethylubiquinone-9 3-methyltransferase
XppCFBP6982P_18030	COG2205	protein histidine kinase activity
XppCFBP6982P_18040	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
XppCFBP6982P_18045	COG3850	Histidine kinase
XppCFBP6982P_18045	COG3437	response regulator, receiver
XppCFBP6982P_18045	COG4999	Histidine kinase
XppCFBP6982P_18045	COG2205	protein histidine kinase activity
XppCFBP6982P_18050	COG0784	Response regulator, receiver
XppCFBP6982P_18050	COG4191	Histidine kinase
XppCFBP6982P_18075	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
XppCFBP6982P_18085	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
XppCFBP6982P_18090	COG0228	four-way junction DNA binding
XppCFBP6982P_18095	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
XppCFBP6982P_18100	COG0336	Belongs to the RNA methyltransferase TrmD family
XppCFBP6982P_18105	COG0335	large ribosomal subunit rRNA binding
XppCFBP6982P_18110	COG0534	Mate efflux family protein
XppCFBP6982P_18135	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
XppCFBP6982P_18145	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
XppCFBP6982P_18185	COG3250	beta-galactosidase activity
XppCFBP6982P_18190	COG3867	Arabinogalactan endo-beta-1,4-galactanase
XppCFBP6982P_18210	COG1960	acyl-CoA dehydrogenase activity
XppCFBP6982P_18240	COG0457	Tetratricopeptide repeat
XppCFBP6982P_18250	COG0457	Tetratricopeptide repeat
XppCFBP6982P_18260	COG1024	Enoyl-CoA hydratase
XppCFBP6982P_18260	COG1250	3-hydroxyacyl-CoA dehydrogenase
XppCFBP6982P_18275	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XppCFBP6982P_18280	COG0481	GTPase activity
XppCFBP6982P_18295	COG0571	ribonuclease III activity
XppCFBP6982P_18300	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
XppCFBP6982P_18305	COG1381	Involved in DNA repair and RecF pathway recombination
XppCFBP6982P_18315	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
XppCFBP6982P_18325	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
XppCFBP6982P_18330	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
XppCFBP6982P_18335	COG3046	protein related to deoxyribodipyrimidine photolyase
XppCFBP6982P_18340	COG1472	Belongs to the glycosyl hydrolase 3 family
XppCFBP6982P_18350	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
XppCFBP6982P_18355	COG1278	Cold shock
XppCFBP6982P_18360	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XppCFBP6982P_18370	COG1201	RNA secondary structure unwinding
XppCFBP6982P_18375	COG1793	dna ligase
XppCFBP6982P_18385	COG1793	dna ligase
XppCFBP6982P_18385	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
XppCFBP6982P_18405	COG3706	GGDEF domain
XppCFBP6982P_18405	COG0745	RESPONSE REGULATOR receiver
XppCFBP6982P_18425	COG0183	Belongs to the thiolase family
XppCFBP6982P_18445	COG1451	nucleotide metabolic process
XppCFBP6982P_18450	COG5487	UPF0391 membrane protein
XppCFBP6982P_18460	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
XppCFBP6982P_18480	COG1077	Cell shape determining protein MreB Mrl
XppCFBP6982P_18485	COG1047	Peptidyl-prolyl cis-trans
XppCFBP6982P_18495	COG2824	Alkylphosphonate utilization operon protein PhnA
XppCFBP6982P_18505	COG1902	pentaerythritol trinitrate reductase activity
XppCFBP6982P_18510	COG2814	Major facilitator Superfamily
XppCFBP6982P_18540	COG0392	lysyltransferase activity
XppCFBP6982P_18540	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
XppCFBP6982P_18550	COG0251	oxidation-reduction process
XppCFBP6982P_18555	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
XppCFBP6982P_18570	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
XppCFBP6982P_18595	COG1595	DNA-templated transcription, initiation
XppCFBP6982P_18610	COG2878	Part of a membrane complex involved in electron transport
XppCFBP6982P_18620	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
XppCFBP6982P_18620	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
XppCFBP6982P_18640	COG0346	lactoylglutathione lyase activity
XppCFBP6982P_18660	COG2040	homocysteine
XppCFBP6982P_18670	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
XppCFBP6982P_18690	COG1695	Transcriptional regulator
XppCFBP6982P_18725	COG0825	malonyl-CoA metabolic process
XppCFBP6982P_18740	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XppCFBP6982P_18745	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XppCFBP6982P_18750	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
XppCFBP6982P_18755	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XppCFBP6982P_18770	COG0750	zinc metalloprotease
XppCFBP6982P_18775	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
XppCFBP6982P_18780	COG0575	Belongs to the CDS family
XppCFBP6982P_18785	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
XppCFBP6982P_18790	COG0233	cytoplasmic translational termination
XppCFBP6982P_18795	COG0528	UMP kinase activity
XppCFBP6982P_18800	COG3706	GGDEF domain
XppCFBP6982P_18800	COG0745	RESPONSE REGULATOR receiver
XppCFBP6982P_18805	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
XppCFBP6982P_18810	COG0052	Belongs to the universal ribosomal protein uS2 family
XppCFBP6982P_18845	COG0024	Methionine aminopeptidase
XppCFBP6982P_18850	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
XppCFBP6982P_18860	COG1393	Belongs to the ArsC family
XppCFBP6982P_18865	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XppCFBP6982P_18870	COG0367	asparagine synthase
XppCFBP6982P_18880	COG4774	siderophore transport
XppCFBP6982P_18935	COG3328	transposase activity
XppCFBP6982P_18970	COG1566	PFAM secretion protein HlyD family protein
XppCFBP6982P_18975	COG2814	Major facilitator Superfamily
XppCFBP6982P_19035	COG0339	signal peptide processing
XppCFBP6982P_19040	COG0386	Belongs to the glutathione peroxidase family
XppCFBP6982P_19100	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
XppCFBP6982P_19105	COG0084	hydrolase, TatD family'
XppCFBP6982P_19120	COG1960	acyl-CoA dehydrogenase activity
XppCFBP6982P_19140	COG0367	asparagine synthase
XppCFBP6982P_19150	COG0305	Participates in initiation and elongation during chromosome replication
XppCFBP6982P_19155	COG0415	Belongs to the DNA photolyase family
XppCFBP6982P_19165	COG0583	DNA-binding transcription factor activity
XppCFBP6982P_19200	COG3706	GGDEF domain
XppCFBP6982P_19210	COG3706	GGDEF domain
XppCFBP6982P_19230	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
XppCFBP6982P_19245	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XppCFBP6982P_19255	COG0497	DNA recombination
XppCFBP6982P_19260	COG1420	regulation of RNA biosynthetic process
XppCFBP6982P_19265	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
XppCFBP6982P_19270	COG0443	Heat shock 70 kDa protein
XppCFBP6982P_19275	COG0484	heat shock protein binding
XppCFBP6982P_19280	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
XppCFBP6982P_19310	COG0583	DNA-binding transcription factor activity
XppCFBP6982P_19315	COG1132	(ABC) transporter
XppCFBP6982P_19350	COG2850	peptidyl-arginine hydroxylation
XppCFBP6982P_19370	COG1253	flavin adenine dinucleotide binding
XppCFBP6982P_19405	COG1131	(ABC) transporter
XppCFBP6982P_19410	COG1725	Transcriptional regulator
XppCFBP6982P_19420	COG0386	Belongs to the glutathione peroxidase family
XppCFBP6982P_19440	COG2900	Belongs to the SlyX family
XppCFBP6982P_19470	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XppCFBP6982P_19480	COG1410	methionine synthase
XppCFBP6982P_19480	COG0646	methionine synthase
XppCFBP6982P_19495	COG1960	acyl-CoA dehydrogenase activity
XppCFBP6982P_19500	COG1960	acyl-CoA dehydrogenase activity
XppCFBP6982P_19515	COG0557	exoribonuclease II activity
XppCFBP6982P_19525	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
XppCFBP6982P_19540	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
XppCFBP6982P_19550	COG0704	Plays a role in the regulation of phosphate uptake
XppCFBP6982P_19555	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
XppCFBP6982P_19560	COG0581	inorganic phosphate transmembrane transporter activity
XppCFBP6982P_19565	COG0573	inorganic phosphate transmembrane transporter activity
XppCFBP6982P_19570	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
XppCFBP6982P_19595	COG0659	secondary active sulfate transmembrane transporter activity
XppCFBP6982P_19600	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
XppCFBP6982P_19610	COG1024	Enoyl-CoA hydratase
XppCFBP6982P_19620	COG0494	nUDIX hydrolase
XppCFBP6982P_19665	COG0116	Belongs to the methyltransferase superfamily
XppCFBP6982P_19665	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
XppCFBP6982P_19670	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
XppCFBP6982P_19690	COG2925	Exonuclease
XppCFBP6982P_19700	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XppCFBP6982P_19705	COG3844	kynureninase activity
XppCFBP6982P_19715	COG0662	Cupin 2, conserved barrel domain protein
XppCFBP6982P_19720	COG0288	reversible hydration of carbon dioxide
XppCFBP6982P_19800	COG0017	Asparaginyl-tRNA synthetase
XppCFBP6982P_19810	COG0316	Belongs to the HesB IscA family
XppCFBP6982P_19815	COG0360	Binds together with S18 to 16S ribosomal RNA
XppCFBP6982P_19820	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
XppCFBP6982P_19825	COG0359	binds to the 23S rRNA
XppCFBP6982P_19835	COG3115	cell septum assembly
XppCFBP6982P_19845	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XppCFBP6982P_19850	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
XppCFBP6982P_19855	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
XppCFBP6982P_19870	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
XppCFBP6982P_19880	COG4993	Dehydrogenase
XppCFBP6982P_19890	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
XppCFBP6982P_19905	COG2986	histidine ammonia-lyase
XppCFBP6982P_19910	COG1228	amidohydrolase
XppCFBP6982P_19950	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
XppCFBP6982P_19955	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
XppCFBP6982P_19960	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
XppCFBP6982P_19965	COG0077	Prephenate dehydratase
XppCFBP6982P_19965	COG1605	Chorismate mutase
XppCFBP6982P_19970	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
XppCFBP6982P_19985	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
XppCFBP6982P_19990	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
XppCFBP6982P_19995	COG0583	DNA-binding transcription factor activity
XppCFBP6982P_20020	COG0840	transmembrane signaling receptor activity
XppCFBP6982P_20040	COG0784	Response regulator, receiver
XppCFBP6982P_20040	COG4191	Histidine kinase
XppCFBP6982P_20050	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
XppCFBP6982P_20070	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XppCFBP6982P_20080	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
XppCFBP6982P_20090	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
XppCFBP6982P_20105	COG1595	DNA-templated transcription, initiation
XppCFBP6982P_20160	COG2244	polysaccharide biosynthetic process
XppCFBP6982P_20190	COG2264	protein methyltransferase activity
XppCFBP6982P_20200	COG0438	transferase activity, transferring glycosyl groups
XppCFBP6982P_20215	COG1136	(ABC) transporter
XppCFBP6982P_20225	COG0477	Major facilitator Superfamily
XppCFBP6982P_20230	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XppCFBP6982P_20245	COG1253	flavin adenine dinucleotide binding
XppCFBP6982P_20260	COG0306	phosphate transporter
XppCFBP6982P_20285	COG0504	CTP synthase activity
XppCFBP6982P_20290	COG2877	3-deoxy-8-phosphooctulonate synthase activity
XppCFBP6982P_20300	COG0148	phosphopyruvate hydratase activity
XppCFBP6982P_20305	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
XppCFBP6982P_20315	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
XppCFBP6982P_20320	COG0585	pseudouridine synthase activity
XppCFBP6982P_20325	COG2840	Smr protein MutS2
XppCFBP6982P_20330	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
XppCFBP6982P_20335	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
XppCFBP6982P_20340	COG1238	metal cluster binding
XppCFBP6982P_20350	COG3737	Protein of unknown function (DUF498/DUF598)
XppCFBP6982P_20355	COG1534	Rna-binding protein
XppCFBP6982P_20360	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
XppCFBP6982P_20365	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
XppCFBP6982P_20370	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
XppCFBP6982P_20375	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
XppCFBP6982P_20380	COG1923	regulation of RNA biosynthetic process
XppCFBP6982P_20385	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
XppCFBP6982P_20390	COG1546	Belongs to the CinA family
XppCFBP6982P_20400	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
XppCFBP6982P_20405	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
XppCFBP6982P_20415	COG2137	regulation of response to DNA damage stimulus
XppCFBP6982P_20420	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
XppCFBP6982P_20425	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
XppCFBP6982P_20450	COG0583	DNA-binding transcription factor activity
XppCFBP6982P_20475	COG0351	phosphomethylpyrimidine kinase
XppCFBP6982P_20490	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
XppCFBP6982P_20495	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
XppCFBP6982P_20510	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
XppCFBP6982P_20520	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
XppCFBP6982P_20525	COG3734	2-keto-3-deoxy-galactonokinase
XppCFBP6982P_20535	COG4948	Mandelate Racemase Muconate Lactonizing
XppCFBP6982P_20540	COG0800	Aldolase
XppCFBP6982P_20580	COG1501	Belongs to the glycosyl hydrolase 31 family
XppCFBP6982P_20590	COG1070	Carbohydrate kinase
XppCFBP6982P_20595	COG2115	Belongs to the xylose isomerase family
XppCFBP6982P_20600	COG0477	Major facilitator Superfamily
XppCFBP6982P_20620	COG0860	N-Acetylmuramoyl-L-alanine amidase
XppCFBP6982P_20625	COG1469	GTP cyclohydrolase I activity
XppCFBP6982P_20650	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
XppCFBP6982P_20655	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
XppCFBP6982P_20660	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
XppCFBP6982P_20665	COG0166	Belongs to the GPI family
XppCFBP6982P_20685	COG1472	Belongs to the glycosyl hydrolase 3 family
XppCFBP6982P_20700	COG3706	GGDEF domain
XppCFBP6982P_20700	COG5001	Diguanylate cyclase
XppCFBP6982P_20700	COG4251	negative regulation of phosphorylation
XppCFBP6982P_20700	COG2203	Gaf domain
XppCFBP6982P_20705	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XppCFBP6982P_20710	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
XppCFBP6982P_20720	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
XppCFBP6982P_20725	COG0671	phosphoesterase, PA-phosphatase related
XppCFBP6982P_20735	COG1794	racemase activity, acting on amino acids and derivatives
XppCFBP6982P_20740	COG0697	spore germination
XppCFBP6982P_20745	COG0812	UDP-N-acetylmuramate dehydrogenase activity
XppCFBP6982P_20750	COG0167	dihydroorotate dehydrogenase activity
XppCFBP6982P_20770	COG1012	belongs to the aldehyde dehydrogenase family
XppCFBP6982P_20785	COG3328	transposase activity
XppCFBP6982P_20790	COG0366	Alpha amylase catalytic
XppCFBP6982P_20810	COG1082	Xylose isomerase domain protein TIM barrel
XppCFBP6982P_20820	COG2211	Major facilitator Superfamily
XppCFBP6982P_20835	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
XppCFBP6982P_20840	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
XppCFBP6982P_20845	COG0291	Belongs to the bacterial ribosomal protein bL35 family
XppCFBP6982P_20850	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
XppCFBP6982P_20855	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
XppCFBP6982P_20860	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
XppCFBP6982P_20860	COG0072	phenylalanine-tRNA ligase activity
XppCFBP6982P_20865	COG0776	regulation of translation
XppCFBP6982P_20910	COG0438	transferase activity, transferring glycosyl groups
XppCFBP6982P_20915	COG0438	transferase activity, transferring glycosyl groups
XppCFBP6982P_20950	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XppCFBP6982P_20960	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XppCFBP6982P_20980	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
XppCFBP6982P_20990	COG1960	acyl-CoA dehydrogenase activity
XppCFBP6982P_21000	COG3040	lipid binding
XppCFBP6982P_21015	COG0322	excinuclease ABC activity
XppCFBP6982P_21030	COG0784	Response regulator, receiver
XppCFBP6982P_21030	COG4191	Histidine kinase
XppCFBP6982P_21050	COG1194	a g-specific adenine glycosylase
XppCFBP6982P_21060	COG0552	protein localization to endoplasmic reticulum
XppCFBP6982P_21070	COG3938	Belongs to the proline racemase family
XppCFBP6982P_21075	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XppCFBP6982P_21090	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
XppCFBP6982P_21100	COG0006	proline dipeptidase activity
XppCFBP6982P_21115	COG0531	amino acid
XppCFBP6982P_21200	COG3039	Transposase
XppCFBP6982P_21205	COG3039	Transposase
XppCFBP6982P_21235	COG3328	transposase activity
XppCFBP6982P_21250	COG3328	transposase activity
XppCFBP6982P_21280	COG3328	transposase activity
XppCFBP6982P_21285	COG0527	aspartate kinase activity
XppCFBP6982P_21285	COG0460	homoserine dehydrogenase
XppCFBP6982P_21320	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XppCFBP6982P_21325	COG0124	histidyl-tRNA synthetase
XppCFBP6982P_21335	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
XppCFBP6982P_21340	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
XppCFBP6982P_21345	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XppCFBP6982P_21350	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
XppCFBP6982P_21350	COG0131	Imidazoleglycerol-phosphate dehydratase
XppCFBP6982P_21355	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
XppCFBP6982P_21360	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
XppCFBP6982P_21365	COG0107	imidazoleglycerol-phosphate synthase activity
XppCFBP6982P_21370	COG0140	phosphoribosyl-ATP diphosphatase activity
XppCFBP6982P_21370	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
XppCFBP6982P_21385	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
XppCFBP6982P_21390	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
XppCFBP6982P_21395	COG0235	Class ii aldolase
XppCFBP6982P_21400	COG0531	amino acid
XppCFBP6982P_21405	COG0531	amino acid
XppCFBP6982P_21415	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
XppCFBP6982P_21420	COG0277	FAD linked oxidase domain protein
XppCFBP6982P_21440	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
XppCFBP6982P_21485	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
XppCFBP6982P_21490	COG2258	MOSC domain
XppCFBP6982P_21495	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
XppCFBP6982P_21500	COG0505	Belongs to the CarA family
XppCFBP6982P_21510	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
XppCFBP6982P_21515	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XppCFBP6982P_21525	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
XppCFBP6982P_21545	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
XppCFBP6982P_21560	COG2205	protein histidine kinase activity
XppCFBP6982P_21560	COG2198	Histidine kinase
XppCFBP6982P_21560	COG0784	Response regulator, receiver
XppCFBP6982P_21565	COG1024	Enoyl-CoA hydratase
XppCFBP6982P_21570	COG0318	PFAM AMP-dependent synthetase and ligase
XppCFBP6982P_21605	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XppCFBP6982P_21615	COG2201	protein-glutamate methylesterase activity
XppCFBP6982P_21620	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
XppCFBP6982P_21630	COG0840	transmembrane signaling receptor activity
XppCFBP6982P_21640	COG0835	chemotaxis
XppCFBP6982P_21655	COG0840	transmembrane signaling receptor activity
XppCFBP6982P_21660	COG0840	transmembrane signaling receptor activity
XppCFBP6982P_21665	COG0840	transmembrane signaling receptor activity
XppCFBP6982P_21670	COG0840	transmembrane signaling receptor activity
XppCFBP6982P_21675	COG0840	transmembrane signaling receptor activity
XppCFBP6982P_21685	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
XppCFBP6982P_21690	COG0840	transmembrane signaling receptor activity
XppCFBP6982P_21695	COG0840	transmembrane signaling receptor activity
XppCFBP6982P_21700	COG0840	transmembrane signaling receptor activity
XppCFBP6982P_21705	COG0840	transmembrane signaling receptor activity
XppCFBP6982P_21720	COG0840	transmembrane signaling receptor activity
XppCFBP6982P_21725	COG0840	transmembrane signaling receptor activity
XppCFBP6982P_21735	COG0840	transmembrane signaling receptor activity
XppCFBP6982P_21740	COG0840	transmembrane signaling receptor activity
XppCFBP6982P_21750	COG0745	RESPONSE REGULATOR receiver
XppCFBP6982P_21760	COG0835	chemotaxis
XppCFBP6982P_21765	COG1192	Involved in chromosome partitioning
XppCFBP6982P_21770	COG1360	Flagellar Motor Protein
XppCFBP6982P_21775	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
XppCFBP6982P_21810	COG3328	transposase activity
XppCFBP6982P_21815	COG0643	Histidine kinase
XppCFBP6982P_21815	COG2198	Histidine kinase
XppCFBP6982P_21835	COG0455	bacterial-type flagellum organization
XppCFBP6982P_21845	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
XppCFBP6982P_21870	COG3039	Transposase
XppCFBP6982P_21880	COG1684	flagellar biosynthetic protein fliR
XppCFBP6982P_21885	COG1987	bacterial-type flagellum assembly
XppCFBP6982P_21900	COG3190	flagellar
XppCFBP6982P_21950	COG1677	Flagellar hook-basal body complex protein FliE
XppCFBP6982P_22005	COG1028	Short-chain dehydrogenase reductase Sdr
XppCFBP6982P_22010	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XppCFBP6982P_22025	COG2204	response regulator
XppCFBP6982P_22030	COG2201	protein-glutamate methylesterase activity
XppCFBP6982P_22060	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
XppCFBP6982P_22070	COG3039	Transposase
XppCFBP6982P_22075	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
XppCFBP6982P_22085	COG1705	Flagellar rod assembly protein muramidase FlgJ
XppCFBP6982P_22085	COG3951	Flagellar rod assembly protein muramidase FlgJ
XppCFBP6982P_22090	COG1706	bacterial-type flagellum-dependent cell motility
XppCFBP6982P_22095	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
XppCFBP6982P_22100	COG4786	Flagellar basal body rod
XppCFBP6982P_22105	COG4787	bacterial-type flagellum-dependent cell motility
XppCFBP6982P_22110	COG1749	Flagellar hook protein flgE
XppCFBP6982P_22115	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
XppCFBP6982P_22120	COG1558	bacterial-type flagellum-dependent cell motility
XppCFBP6982P_22130	COG0784	Response regulator, receiver
XppCFBP6982P_22130	COG0835	chemotaxis
XppCFBP6982P_22150	COG5002	protein histidine kinase activity
XppCFBP6982P_22160	COG4585	Histidine kinase
XppCFBP6982P_22180	COG2915	High frequency lysogenization protein hflD homolog
XppCFBP6982P_22185	COG0482	sulfurtransferase activity
XppCFBP6982P_22195	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
XppCFBP6982P_22200	COG0542	response to heat
XppCFBP6982P_22205	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
XppCFBP6982P_22210	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
XppCFBP6982P_22220	COG0492	ferredoxin-NADP+ reductase activity
XppCFBP6982P_22225	COG1674	ftsk spoiiie
XppCFBP6982P_22235	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
XppCFBP6982P_22245	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
XppCFBP6982P_22250	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
XppCFBP6982P_22255	COG0183	Belongs to the thiolase family
XppCFBP6982P_22260	COG1250	3-hydroxyacyl-CoA dehydrogenase
XppCFBP6982P_22260	COG1024	Enoyl-CoA hydratase
XppCFBP6982P_22270	COG0105	UTP biosynthetic process
XppCFBP6982P_22295	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XppCFBP6982P_22300	COG1160	GTP binding
XppCFBP6982P_22305	COG0303	'Molybdopterin
XppCFBP6982P_22310	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
XppCFBP6982P_22345	COG0708	Exodeoxyribonuclease III
XppCFBP6982P_22355	COG0303	'Molybdopterin
XppCFBP6982P_22360	COG0746	molybdenum cofactor guanylyltransferase activity
XppCFBP6982P_22385	COG1648	precorrin-2 dehydrogenase activity
XppCFBP6982P_22385	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
XppCFBP6982P_22395	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
XppCFBP6982P_22400	COG2223	nitrite transmembrane transporter activity
XppCFBP6982P_22405	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
XppCFBP6982P_22415	COG0243	molybdopterin cofactor binding
XppCFBP6982P_22430	COG3685	Protein conserved in bacteria
XppCFBP6982P_22450	COG5001	Diguanylate cyclase
XppCFBP6982P_22460	COG4566	intracellular signal transduction
XppCFBP6982P_22515	COG3328	transposase activity
XppCFBP6982P_22530	COG3039	Transposase
XppCFBP6982P_22540	COG3328	transposase activity
XppCFBP6982P_22550	COG2226	methyltransferase
XppCFBP6982P_22550	COG1073	alpha beta
XppCFBP6982P_22565	COG0363	glucosamine-6-phosphate deaminase activity
XppCFBP6982P_22685	COG2951	lytic endotransglycosylase activity
XppCFBP6982P_22705	COG0551	DNA topoisomerase type I activity
XppCFBP6982P_22705	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
XppCFBP6982P_22740	COG3846	protein secretion by the type IV secretion system
XppCFBP6982P_22755	COG3328	transposase activity
XppCFBP6982P_22770	COG4962	Type ii secretion system protein e
XppCFBP6982P_22880	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
XppCFBP6982P_22885	COG4691	Plasmid stability protein
XppCFBP6982P_22890	COG1487	ribonuclease activity
XppCFBP6982P_22970	COG3328	transposase activity
XppCFBP6982P_23085	COG3328	transposase activity
XppCFBP6982P_23145	COG1487	ribonuclease activity
XppCFBP6982P_23150	COG4691	Plasmid stability protein
XppCFBP6982P_23155	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
XppCFBP6982P_23280	COG3039	Transposase
XppCFBP6982P_23340	COG3328	transposase activity
XppCFBP6982P_23395	COG1192	Involved in chromosome partitioning
XppCFBP6982P_23415	COG3328	transposase activity
XppCFBP6982P_23520	COG3328	transposase activity
XppCFBP6982P_23555	COG3012	SEC-C Motif Domain Protein
XppCFBP6982P_23555	COG3318	Belongs to the UPF0149 family
XppCFBP6982P_23600	COG1192	Involved in chromosome partitioning
XppCFBP6982P_23620	COG3328	transposase activity