locus-tag	class	description
OM947_00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
OM947_00020	COG0187	DNA topoisomerase II activity
OM947_00030	COG0501	Belongs to the peptidase M48B family
OM947_00075	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
OM947_00085	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OM947_00130	COG0793	Belongs to the peptidase S41A family
OM947_00135	COG4942	peptidase
OM947_00145	COG2234	aminopeptidase activity
OM947_00155	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
OM947_00160	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
OM947_00170	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
OM947_00175	COG1064	alcohol dehydrogenase
OM947_00190	COG0493	'glutamate synthase
OM947_00195	COG0067	glutamate synthase
OM947_00195	COG0069	glutamate synthase activity
OM947_00195	COG0070	glutamate synthase
OM947_00285	COG1205	dead DEAH box helicase
OM947_00285	COG1111	helicase
OM947_00290	COG1272	protein, Hemolysin III
OM947_00310	COG0300	oxidoreductase activity
OM947_00315	COG1028	Short-chain dehydrogenase reductase Sdr
OM947_00340	COG2249	NAD(P)H dehydrogenase (quinone) activity
OM947_00350	COG3039	Transposase
OM947_00365	COG3039	Transposase
OM947_00375	COG3237	CsbD-like
OM947_00425	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OM947_00475	COG0714	Associated with various cellular activities
OM947_00515	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
OM947_00525	COG4772	TonB-dependent receptor
OM947_00550	COG1304	FMN binding
OM947_00555	COG1755	Isoprenylcysteine carboxyl methyltransferase
OM947_00560	COG4585	Histidine kinase
OM947_00565	COG2197	response regulator
OM947_00590	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
OM947_00655	COG3328	transposase activity
OM947_00670	COG3039	Transposase
OM947_00685	COG0366	Alpha amylase catalytic
OM947_00690	COG0366	Alpha amylase catalytic
OM947_00695	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
OM947_00715	COG0657	acetylesterase activity
OM947_00715	COG2755	lipolytic protein G-D-S-L family
OM947_00725	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
OM947_00740	COG3507	Belongs to the glycosyl hydrolase 43 family
OM947_00745	COG1609	Transcriptional regulator
OM947_00750	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
OM947_00755	COG1028	Short-chain dehydrogenase reductase Sdr
OM947_00765	COG2755	lipolytic protein G-D-S-L family
OM947_00775	COG3186	Phenylalanine-4-hydroxylase
OM947_00780	COG1522	sequence-specific DNA binding
OM947_00790	COG1752	Esterase of the alpha-beta hydrolase superfamily
OM947_00800	COG1119	ATPase activity
OM947_00815	COG0517	IMP dehydrogenase activity
OM947_00815	COG1125	glycine betaine transport
OM947_00830	COG1262	PFAM Formylglycine-generating sulfatase enzyme
OM947_00860	COG0489	protein tyrosine kinase activity
OM947_00865	COG2062	phosphohistidine phosphatase, SixA
OM947_00875	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OM947_00915	COG1968	undecaprenyl-diphosphatase activity
OM947_00920	COG0174	glutamine synthetase
OM947_00925	COG0347	Belongs to the P(II) protein family
OM947_00930	COG0004	ammonium transporteR
OM947_00935	COG3852	Histidine kinase
OM947_00940	COG2204	response regulator
OM947_00945	COG2032	superoxide dismutase activity
OM947_00950	COG2032	superoxide dismutase activity
OM947_00965	COG0183	Belongs to the thiolase family
OM947_01000	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OM947_01005	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
OM947_01010	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
OM947_01035	COG2205	protein histidine kinase activity
OM947_01060	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
OM947_01075	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OM947_01080	COG3177	Filamentation induced by cAMP protein fic
OM947_01085	COG0596	Alpha beta hydrolase
OM947_01090	COG0727	PFAM Uncharacterised protein family (UPF0153)
OM947_01095	COG0318	PFAM AMP-dependent synthetase and ligase
OM947_01100	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OM947_01115	COG1181	Belongs to the D-alanine--D-alanine ligase family
OM947_01125	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
OM947_01135	COG0564	pseudouridine synthase activity
OM947_01155	COG1446	asparaginase
OM947_01160	COG0339	signal peptide processing
OM947_01195	COG0475	glutathione-regulated potassium exporter activity
OM947_01200	COG0583	DNA-binding transcription factor activity
OM947_01205	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
OM947_01210	COG2224	Isocitrate lyase
OM947_01230	COG3039	Transposase
OM947_01250	COG4770	biotin carboxylase activity
OM947_01255	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
OM947_01260	COG1960	acyl-CoA dehydrogenase activity
OM947_01325	COG0697	spore germination
OM947_01335	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
OM947_01340	COG1846	Transcriptional regulator
OM947_01345	COG1764	response to oxidative stress
OM947_01365	COG2130	NADP-dependent
OM947_01380	COG1187	pseudouridine synthase activity
OM947_01390	COG1643	Atp-dependent helicase
OM947_01395	COG4807	Protein conserved in bacteria
OM947_01405	COG2072	flavoprotein involved in K transport
OM947_01425	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
OM947_01435	COG0583	DNA-binding transcription factor activity
OM947_01470	COG2252	PERMEase
OM947_01490	COG0084	hydrolase, TatD family'
OM947_01505	COG0583	DNA-binding transcription factor activity
OM947_01510	COG2814	Major facilitator Superfamily
OM947_01525	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
OM947_01530	COG1902	pentaerythritol trinitrate reductase activity
OM947_01550	COG0745	RESPONSE REGULATOR receiver
OM947_01555	COG2205	protein histidine kinase activity
OM947_01560	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OM947_01585	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
OM947_01590	COG0583	DNA-binding transcription factor activity
OM947_01625	COG0702	epimerase
OM947_01630	COG1733	regulation of RNA biosynthetic process
OM947_01675	COG0129	dihydroxy-acid dehydratase activity
OM947_01690	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
OM947_01745	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
OM947_01750	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
OM947_01775	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
OM947_01790	COG3485	protocatechuate 3,4-dioxygenase
OM947_01795	COG3485	protocatechuate 3,4-dioxygenase
OM947_01805	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OM947_01810	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OM947_01820	COG1414	Transcriptional regulator
OM947_01830	COG0657	acetylesterase activity
OM947_01840	COG0445	tRNA wobble uridine modification
OM947_01850	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
OM947_01880	COG2267	carboxylic ester hydrolase activity
OM947_01890	COG0156	8-amino-7-oxononanoate synthase activity
OM947_01895	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
OM947_01900	COG1040	competence protein
OM947_01905	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
OM947_01925	COG3039	Transposase
OM947_01990	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
OM947_02060	COG1511	domain protein
OM947_02060	COG3264	Mechanosensitive ion channel
OM947_02065	COG1368	sulfuric ester hydrolase activity
OM947_02070	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
OM947_02075	COG2354	Protein conserved in bacteria
OM947_02085	COG0297	glycogen (starch) synthase activity
OM947_02090	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
OM947_02095	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
OM947_02120	COG0702	epimerase
OM947_02130	COG1858	cytochrome C peroxidase
OM947_02145	COG3328	transposase activity
OM947_02155	COG3039	Transposase
OM947_02165	COG1028	Short-chain dehydrogenase reductase Sdr
OM947_02200	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OM947_02205	COG1028	Short-chain dehydrogenase reductase Sdr
OM947_02215	COG0513	Belongs to the DEAD box helicase family
OM947_02220	COG0508	dehydrogenase complex catalyzes the overall conversion of
OM947_02235	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
OM947_02245	COG3483	tryptophan 2,3-dioxygenase activity
OM947_02250	COG3104	oligopeptide transport
OM947_02270	COG2852	Protein conserved in bacteria
OM947_02275	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
OM947_02295	COG1320	monovalent cation:proton antiporter activity
OM947_02300	COG2212	antiporter activity
OM947_02310	COG0651	ATP synthesis coupled electron transport
OM947_02315	COG1006	Multisubunit Na H antiporter MnhC subunit
OM947_02320	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
OM947_02320	COG2111	Na H antiporter
OM947_02340	COG3179	chitinase
OM947_02360	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
OM947_02365	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
OM947_02385	COG1597	lipid kinase activity
OM947_02415	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
OM947_02420	COG0134	indole-3-glycerol-phosphate synthase activity
OM947_02430	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OM947_02435	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
OM947_02445	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
OM947_02455	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
OM947_02470	COG1051	belongs to the nudix hydrolase family
OM947_02510	COG0316	Belongs to the HesB IscA family
OM947_02525	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
OM947_02540	COG2814	Major facilitator Superfamily
OM947_02550	COG2814	Major facilitator Superfamily
OM947_02555	COG1289	transmembrane transporter activity
OM947_02565	COG0151	Belongs to the GarS family
OM947_02575	COG0138	bifunctional purine biosynthesis protein purh
OM947_02580	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
OM947_02585	COG2267	carboxylic ester hydrolase activity
OM947_02590	COG0671	phosphoesterase, PA-phosphatase related
OM947_02590	COG2453	phosphatase
OM947_02615	COG4589	Belongs to the CDS family
OM947_02620	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
OM947_02640	COG2264	protein methyltransferase activity
OM947_02655	COG0439	Biotin carboxylase
OM947_02665	COG0511	ligase activity, forming carbon-carbon bonds
OM947_02670	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
OM947_02680	COG1324	tolerance protein
OM947_02700	COG0459	protein refolding
OM947_02715	COG3550	peptidyl-serine autophosphorylation
OM947_02720	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
OM947_02735	COG3386	PFAM SMP-30 Gluconolaconase
OM947_02745	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
OM947_02750	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
OM947_02775	COG3039	Transposase
OM947_02795	COG0778	Nitroreductase
OM947_02800	COG2353	YceI-like domain
OM947_02835	COG3052	prosthetic group binding
OM947_02860	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
OM947_02870	COG1802	Transcriptional regulator
OM947_02925	COG3328	transposase activity
OM947_02935	COG4221	oxidoreductase activity
OM947_02965	COG4221	oxidoreductase activity
OM947_02975	COG0435	Glutathione S-transferase
OM947_03040	COG1959	2 iron, 2 sulfur cluster binding
OM947_03065	COG0697	spore germination
OM947_03070	COG4305	rare lipoprotein A
OM947_03075	COG5297	Belongs to the glycosyl hydrolase family 6
OM947_03085	COG1113	amino acid transport
OM947_03095	COG0598	Magnesium transport protein CorA
OM947_03140	COG5002	protein histidine kinase activity
OM947_03140	COG5001	Diguanylate cyclase
OM947_03140	COG3447	MASE1 domain protein
OM947_03155	COG2205	protein histidine kinase activity
OM947_03155	COG0784	Response regulator, receiver
OM947_03190	COG2943	transferase activity, transferring hexosyl groups
OM947_03200	COG3275	phosphorelay sensor kinase activity
OM947_03210	COG0181	hydroxymethylbilane synthase activity
OM947_03245	COG1505	serine-type exopeptidase activity
OM947_03255	COG0436	Aminotransferase
OM947_03265	COG2832	Protein of unknown function (DUF454)
OM947_03275	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
OM947_03285	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
OM947_03290	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
OM947_03295	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
OM947_03320	COG2226	methyltransferase
OM947_03325	COG3300	MHYT domain
OM947_03325	COG5001	Diguanylate cyclase
OM947_03330	COG0308	aminopeptidase N
OM947_03375	COG3284	Transcriptional regulator
OM947_03390	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OM947_03395	COG1077	Cell shape determining protein MreB Mrl
OM947_03400	COG1792	Involved in formation and maintenance of cell shape
OM947_03415	COG0772	Belongs to the SEDS family
OM947_03430	COG3039	Transposase
OM947_03465	COG2951	lytic endotransglycosylase activity
OM947_03470	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
OM947_03475	COG1686	Belongs to the peptidase S11 family
OM947_03485	COG2921	Belongs to the UPF0250 family
OM947_03490	COG0321	lipoyl(octanoyl) transferase activity
OM947_03495	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
OM947_03520	COG1051	belongs to the nudix hydrolase family
OM947_03520	COG1056	cytidyltransferase-related domain
OM947_03555	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
OM947_03560	COG0673	inositol 2-dehydrogenase activity
OM947_03565	COG2823	Periplasmic or secreted lipoprotein
OM947_03570	COG4251	negative regulation of phosphorylation
OM947_03575	COG0784	Response regulator, receiver
OM947_03580	COG4191	Histidine kinase
OM947_03585	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
OM947_03640	COG1459	type II secretion system
OM947_03685	COG2188	Transcriptional regulator
OM947_03695	COG1609	Transcriptional regulator
OM947_03700	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
OM947_03705	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
OM947_03715	COG0617	tRNA 3'-terminal CCA addition
OM947_03730	COG0525	valine-tRNA ligase activity
OM947_03745	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
OM947_03755	COG0795	lipopolysaccharide-transporting ATPase activity
OM947_03770	COG4974	Belongs to the 'phage' integrase family
OM947_03780	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
OM947_03785	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
OM947_03785	COG0047	phosphoribosylformylglycinamidine synthase activity
OM947_03790	COG5295	Hep Hag repeat protein
OM947_03795	COG1404	Belongs to the peptidase S8 family
OM947_03800	COG5295	Hep Hag repeat protein
OM947_03805	COG1404	Belongs to the peptidase S8 family
OM947_03810	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
OM947_03815	COG1459	type II secretion system
OM947_03820	COG2165	general secretion pathway protein
OM947_03825	COG4970	Tfp pilus assembly protein FimT
OM947_03830	COG2165	general secretion pathway protein
OM947_03835	COG4795	General secretion pathway protein
OM947_03840	COG3156	type II secretion system protein K
OM947_03845	COG3166	PFAM Fimbrial assembly family protein
OM947_03860	COG1450	Type ii and iii secretion system protein
OM947_03870	COG2188	Transcriptional regulator
OM947_03940	COG1215	transferase activity, transferring glycosyl groups
OM947_03945	COG1215	transferase activity, transferring glycosyl groups
OM947_03950	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
OM947_03975	COG0242	peptide deformylase activity
OM947_03980	COG0488	(ABC) transporter
OM947_03990	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
OM947_03995	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
OM947_04005	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OM947_04005	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OM947_04025	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
OM947_04030	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
OM947_04035	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
OM947_04050	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
OM947_04055	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
OM947_04065	COG2205	protein histidine kinase activity
OM947_04070	COG0745	RESPONSE REGULATOR receiver
OM947_04080	COG0277	FAD linked oxidase domain protein
OM947_04085	COG1988	membrane-bound metal-dependent
OM947_04090	COG0792	nuclease activity
OM947_04130	COG3116	cell division
OM947_04140	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
OM947_04145	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
OM947_04150	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
OM947_04160	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
OM947_04165	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
OM947_04170	COG1181	Belongs to the D-alanine--D-alanine ligase family
OM947_04175	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
OM947_04190	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
OM947_04200	COG0739	heme binding
OM947_04205	COG0653	protein targeting
OM947_04210	COG0494	nUDIX hydrolase
OM947_04220	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
OM947_04245	COG0366	Alpha amylase catalytic
OM947_04280	COG2226	methyltransferase
OM947_04285	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
OM947_04295	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
OM947_04335	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
OM947_04345	COG4106	trans-aconitate 2-methyltransferase activity
OM947_04350	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OM947_04365	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OM947_04370	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
OM947_04375	COG0667	Aldo Keto reductase
OM947_04385	COG4771	TonB-dependent receptor
OM947_04405	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OM947_04410	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
OM947_04420	COG2175	clavaminate synthase activity
OM947_04430	COG4181	ATPase activity
OM947_04445	COG0642	Histidine kinase
OM947_04455	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
OM947_04465	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
OM947_04475	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
OM947_04480	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
OM947_04495	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
OM947_04500	COG2967	ApaG domain
OM947_04505	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
OM947_04510	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
OM947_04515	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
OM947_04520	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
OM947_04530	COG0123	including yeast histone deacetylase and acetoin utilization protein
OM947_04535	COG2096	Adenosyltransferase
OM947_04545	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OM947_04550	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OM947_04580	COG3384	dioxygenase
OM947_04585	COG0583	DNA-binding transcription factor activity
OM947_04590	COG0318	PFAM AMP-dependent synthetase and ligase
OM947_04600	COG1024	Enoyl-CoA hydratase
OM947_04620	COG3386	PFAM SMP-30 Gluconolaconase
OM947_04630	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
OM947_04655	COG0697	spore germination
OM947_04665	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OM947_04690	COG2197	response regulator
OM947_04700	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OM947_04715	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
OM947_04720	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
OM947_04725	COG0583	DNA-binding transcription factor activity
OM947_04730	COG3634	alkyl hydroperoxide reductase activity
OM947_04740	COG2890	protein-(glutamine-N5) methyltransferase activity
OM947_04760	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OM947_04760	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OM947_04815	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
OM947_04820	COG1404	Belongs to the peptidase S8 family
OM947_04825	COG1404	Belongs to the peptidase S8 family
OM947_04830	COG1404	Belongs to the peptidase S8 family
OM947_04835	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
OM947_04860	COG1295	ribonuclease BN
OM947_04865	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OM947_04870	COG1254	Belongs to the acylphosphatase family
OM947_04885	COG0521	Mo-molybdopterin cofactor biosynthetic process
OM947_04895	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
OM947_04900	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
OM947_04910	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
OM947_04915	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
OM947_04925	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
OM947_04930	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
OM947_04935	COG0193	aminoacyl-tRNA hydrolase activity
OM947_04940	COG0012	GTP binding
OM947_04960	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
OM947_04975	COG0250	Participates in transcription elongation, termination and antitermination
OM947_04980	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
OM947_04985	COG0081	regulation of translation
OM947_04990	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
OM947_05000	COG0085	RNA polymerase activity
OM947_05005	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
OM947_05010	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
OM947_05015	COG0049	tRNA binding
OM947_05020	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
OM947_05025	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
OM947_05045	COG3328	transposase activity
OM947_05050	COG0051	transcription antitermination factor activity, RNA binding
OM947_05055	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
OM947_05060	COG0088	Forms part of the polypeptide exit tunnel
OM947_05065	COG0089	rRNA binding
OM947_05070	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
OM947_05075	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
OM947_05085	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
OM947_05090	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
OM947_05095	COG0255	Belongs to the universal ribosomal protein uL29 family
OM947_05100	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
OM947_05110	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
OM947_05115	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
OM947_05125	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
OM947_05130	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
OM947_05135	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
OM947_05145	COG1841	ribosomal large subunit assembly
OM947_05150	COG0200	Binds to the 23S rRNA
OM947_05155	COG0201	protein transport
OM947_05180	COG0203	ribosomal protein L17
OM947_05185	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
OM947_05205	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
OM947_05215	COG0154	amidase activity
OM947_05225	COG1217	gtp-binding protein TYPA
OM947_05230	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
OM947_05235	COG0039	L-malate dehydrogenase activity
OM947_05240	COG0625	glutathione transferase activity
OM947_05255	COG0446	pyridine nucleotide-disulphide oxidoreductase
OM947_05255	COG1902	pentaerythritol trinitrate reductase activity
OM947_05260	COG0604	alcohol dehydrogenase
OM947_05265	COG3039	Transposase
OM947_05270	COG2885	chlorophyll binding
OM947_05290	COG0156	8-amino-7-oxononanoate synthase activity
OM947_05295	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
OM947_05300	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
OM947_05305	COG4208	sulfate ABC transporter
OM947_05310	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
OM947_05345	COG0406	alpha-ribazole phosphatase activity
OM947_05355	COG0285	dihydrofolate synthase activity
OM947_05375	COG2833	Protein of unknown function (DUF455)
OM947_05390	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
OM947_05395	COG0671	phosphoesterase, PA-phosphatase related
OM947_05400	COG0438	transferase activity, transferring glycosyl groups
OM947_05410	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
OM947_05425	COG4783	chaperone-mediated protein folding
OM947_05440	COG0473	3-isopropylmalate dehydrogenase activity
OM947_05480	COG3328	transposase activity
OM947_05495	COG0544	peptidyl-prolyl cis-trans isomerase activity
OM947_05505	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
OM947_05535	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
OM947_05545	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OM947_05555	COG0328	RNA-DNA hybrid ribonuclease activity
OM947_05560	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
OM947_05565	COG0631	protein serine/threonine phosphatase activity
OM947_05590	COG0859	PFAM glycosyl transferase family 9
OM947_05595	COG3642	lipopolysaccharide core region biosynthetic process
OM947_05600	COG1234	tRNA 3'-trailer cleavage
OM947_05605	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
OM947_05615	COG0315	cyclic pyranopterin monophosphate synthase activity
OM947_05620	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
OM947_05625	COG0314	molybdopterin synthase activity
OM947_05645	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
OM947_05650	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
OM947_05655	COG0537	adenosine 5'-monophosphoramidase activity
OM947_05675	COG0714	Associated with various cellular activities
OM947_05685	COG0424	maF-like protein
OM947_05690	COG1399	metal-binding, possibly nucleic acid-binding protein
OM947_05695	COG0333	Belongs to the bacterial ribosomal protein bL32 family
OM947_05700	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OM947_05715	COG1028	Short-chain dehydrogenase reductase Sdr
OM947_05730	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
OM947_05735	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
OM947_05765	COG3829	transcription factor binding
OM947_05810	COG2373	Large extracellular alpha-helical protein
OM947_05830	COG3852	Histidine kinase
OM947_05835	COG4953	penicillin-binding protein 1C
OM947_05845	COG0678	peroxiredoxin activity
OM947_05865	COG0330	HflC and HflK could
OM947_05870	COG0330	HflC and HflK could
OM947_05880	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
OM947_05885	COG0308	aminopeptidase N
OM947_05895	COG1028	Short-chain dehydrogenase reductase Sdr
OM947_05900	COG1309	transcriptional regulator
OM947_05945	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
OM947_05955	COG3387	PFAM Glycoside hydrolase 15-related
OM947_05960	COG1028	Short-chain dehydrogenase reductase Sdr
OM947_05965	COG3537	Alpha-1,2-mannosidase
OM947_05990	COG0492	ferredoxin-NADP+ reductase activity
OM947_06020	COG1529	Aldehyde oxidase and xanthine dehydrogenase
OM947_06025	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
OM947_06030	COG2080	2 iron, 2 sulfur cluster binding
OM947_06065	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
OM947_06080	COG0587	DNA-directed DNA polymerase activity
OM947_06100	COG1297	OPT oligopeptide transporter protein
OM947_06125	COG0823	Involved in the tonB-independent uptake of proteins
OM947_06125	COG1506	peptidase
OM947_06155	COG1917	Cupin 2, conserved barrel domain protein
OM947_06155	COG2207	Transcriptional regulator
OM947_06160	COG3328	transposase activity
OM947_06165	COG0753	catalase activity
OM947_06170	COG0656	L-ascorbic acid biosynthetic process
OM947_06180	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
OM947_06180	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
OM947_06205	COG2814	Major facilitator Superfamily
OM947_06235	COG2194	sulfuric ester hydrolase activity
OM947_06250	COG0745	RESPONSE REGULATOR receiver
OM947_06255	COG0642	Histidine kinase
OM947_06265	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
OM947_06270	COG2894	cell division
OM947_06275	COG0850	regulation of cytokinetic process
OM947_06285	COG4585	Histidine kinase
OM947_06290	COG2197	response regulator
OM947_06305	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
OM947_06330	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
OM947_06340	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
OM947_06355	COG1595	DNA-templated transcription, initiation
OM947_06365	COG1946	Acyl-CoA thioesterase
OM947_06380	COG0824	Thioesterase
OM947_06385	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
OM947_06390	COG0261	This protein binds to 23S rRNA in the presence of protein L20
OM947_06395	COG0211	Belongs to the bacterial ribosomal protein bL27 family
OM947_06400	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
OM947_06405	COG0268	Binds directly to 16S ribosomal RNA
OM947_06415	COG0196	riboflavin kinase activity
OM947_06420	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
OM947_06425	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
OM947_06430	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
OM947_06530	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OM947_06530	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
OM947_06560	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
OM947_06565	COG1845	cytochrome c oxidase, subunit III
OM947_06570	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
OM947_06585	COG3152	Membrane
OM947_06595	COG2207	Transcriptional regulator
OM947_06600	COG0326	Molecular chaperone. Has ATPase activity
OM947_06610	COG1366	Belongs to the anti-sigma-factor antagonist family
OM947_06615	COG1366	Belongs to the anti-sigma-factor antagonist family
OM947_06645	COG4771	TonB-dependent receptor
OM947_06655	COG5507	3-demethylubiquinone-9 3-methyltransferase
OM947_06660	COG2205	protein histidine kinase activity
OM947_06670	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
OM947_06675	COG3850	Histidine kinase
OM947_06675	COG4999	Histidine kinase
OM947_06675	COG2205	protein histidine kinase activity
OM947_06675	COG3437	response regulator, receiver
OM947_06680	COG0784	Response regulator, receiver
OM947_06680	COG4191	Histidine kinase
OM947_06705	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
OM947_06715	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
OM947_06720	COG0228	four-way junction DNA binding
OM947_06725	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
OM947_06730	COG0336	Belongs to the RNA methyltransferase TrmD family
OM947_06735	COG0335	large ribosomal subunit rRNA binding
OM947_06740	COG0534	Mate efflux family protein
OM947_06765	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
OM947_06775	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
OM947_06780	COG2801	Transposase and inactivated derivatives
OM947_06800	COG3328	transposase activity
OM947_06815	COG3328	transposase activity
OM947_06850	COG3250	beta-galactosidase activity
OM947_06855	COG3867	Arabinogalactan endo-beta-1,4-galactanase
OM947_06875	COG1960	acyl-CoA dehydrogenase activity
OM947_06905	COG0457	Tetratricopeptide repeat
OM947_06915	COG0457	Tetratricopeptide repeat
OM947_06925	COG1250	3-hydroxyacyl-CoA dehydrogenase
OM947_06925	COG1024	Enoyl-CoA hydratase
OM947_06940	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OM947_06945	COG0481	GTPase activity
OM947_06960	COG0571	ribonuclease III activity
OM947_06965	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
OM947_06970	COG1381	Involved in DNA repair and RecF pathway recombination
OM947_06980	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
OM947_06985	COG2954	triphosphatase activity
OM947_06990	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
OM947_06995	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
OM947_07000	COG3046	protein related to deoxyribodipyrimidine photolyase
OM947_07005	COG1472	Belongs to the glycosyl hydrolase 3 family
OM947_07010	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
OM947_07015	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
OM947_07020	COG1278	Cold shock
OM947_07025	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OM947_07035	COG1201	RNA secondary structure unwinding
OM947_07040	COG1793	dna ligase
OM947_07050	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
OM947_07050	COG1793	dna ligase
OM947_07085	COG0183	Belongs to the thiolase family
OM947_07105	COG1451	nucleotide metabolic process
OM947_07110	COG5487	UPF0391 membrane protein
OM947_07120	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
OM947_07135	COG1077	Cell shape determining protein MreB Mrl
OM947_07140	COG1047	Peptidyl-prolyl cis-trans
OM947_07150	COG2824	Alkylphosphonate utilization operon protein PhnA
OM947_07160	COG1902	pentaerythritol trinitrate reductase activity
OM947_07165	COG2814	Major facilitator Superfamily
OM947_07200	COG0392	lysyltransferase activity
OM947_07200	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
OM947_07210	COG0251	oxidation-reduction process
OM947_07215	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
OM947_07230	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
OM947_07255	COG1595	DNA-templated transcription, initiation
OM947_07270	COG2878	Part of a membrane complex involved in electron transport
OM947_07280	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OM947_07280	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OM947_07300	COG0346	lactoylglutathione lyase activity
OM947_07315	COG0833	amino acid
OM947_07320	COG2040	homocysteine
OM947_07330	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
OM947_07350	COG1695	Transcriptional regulator
OM947_07370	COG1981	membrane
OM947_07385	COG0825	malonyl-CoA metabolic process
OM947_07400	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
OM947_07405	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
OM947_07410	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
OM947_07415	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
OM947_07430	COG0750	zinc metalloprotease
OM947_07435	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
OM947_07440	COG0575	Belongs to the CDS family
OM947_07445	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
OM947_07450	COG0233	cytoplasmic translational termination
OM947_07455	COG0528	UMP kinase activity
OM947_07465	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
OM947_07470	COG0052	Belongs to the universal ribosomal protein uS2 family
OM947_07520	COG1393	Belongs to the ArsC family
OM947_07525	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
OM947_07535	COG0367	asparagine synthase
OM947_07545	COG4774	siderophore transport
OM947_07595	COG2801	Transposase and inactivated derivatives
OM947_07600	COG3328	transposase activity
OM947_07635	COG1566	PFAM secretion protein HlyD family protein
OM947_07640	COG2814	Major facilitator Superfamily
OM947_07670	COG3104	oligopeptide transport
OM947_07700	COG0339	signal peptide processing
OM947_07705	COG0386	Belongs to the glutathione peroxidase family
OM947_07765	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
OM947_07770	COG0084	hydrolase, TatD family'
OM947_07785	COG1960	acyl-CoA dehydrogenase activity
OM947_07800	COG0367	asparagine synthase
OM947_07810	COG0305	Participates in initiation and elongation during chromosome replication
OM947_07815	COG0415	Belongs to the DNA photolyase family
OM947_07830	COG0583	DNA-binding transcription factor activity
OM947_07875	COG3706	GGDEF domain
OM947_07900	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
OM947_07915	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
OM947_07925	COG0497	DNA recombination
OM947_07930	COG1420	regulation of RNA biosynthetic process
OM947_07935	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
OM947_07940	COG0443	Heat shock 70 kDa protein
OM947_07945	COG0484	heat shock protein binding
OM947_07950	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
OM947_07980	COG0583	DNA-binding transcription factor activity
OM947_07985	COG1132	(ABC) transporter
OM947_08020	COG2850	peptidyl-arginine hydroxylation
OM947_08040	COG1253	flavin adenine dinucleotide binding
OM947_08070	COG1131	(ABC) transporter
OM947_08075	COG1725	Transcriptional regulator
OM947_08085	COG0386	Belongs to the glutathione peroxidase family
OM947_08100	COG2900	Belongs to the SlyX family
OM947_08130	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OM947_08140	COG1410	methionine synthase
OM947_08140	COG0646	methionine synthase
OM947_08145	COG1410	methionine synthase
OM947_08145	COG0646	methionine synthase
OM947_08150	COG2226	methyltransferase
OM947_08155	COG1960	acyl-CoA dehydrogenase activity
OM947_08175	COG0557	exoribonuclease II activity
OM947_08185	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OM947_08195	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
OM947_08205	COG0704	Plays a role in the regulation of phosphate uptake
OM947_08210	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
OM947_08215	COG0581	inorganic phosphate transmembrane transporter activity
OM947_08220	COG0573	inorganic phosphate transmembrane transporter activity
OM947_08225	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
OM947_08250	COG0659	secondary active sulfate transmembrane transporter activity
OM947_08255	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
OM947_08265	COG1024	Enoyl-CoA hydratase
OM947_08275	COG0494	nUDIX hydrolase
OM947_08310	COG0488	(ABC) transporter
OM947_08320	COG0116	Belongs to the methyltransferase superfamily
OM947_08320	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
OM947_08325	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
OM947_08345	COG2925	Exonuclease
OM947_08355	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OM947_08360	COG3844	kynureninase activity
OM947_08370	COG0662	Cupin 2, conserved barrel domain protein
OM947_08375	COG0288	reversible hydration of carbon dioxide
OM947_08455	COG0017	Asparaginyl-tRNA synthetase
OM947_08460	COG0316	Belongs to the HesB IscA family
OM947_08465	COG0360	Binds together with S18 to 16S ribosomal RNA
OM947_08470	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
OM947_08475	COG0359	binds to the 23S rRNA
OM947_08485	COG3115	cell septum assembly
OM947_08495	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
OM947_08500	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
OM947_08505	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
OM947_08515	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
OM947_08525	COG4993	Dehydrogenase
OM947_08535	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
OM947_08545	COG2986	histidine ammonia-lyase
OM947_08550	COG1228	amidohydrolase
OM947_08590	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
OM947_08595	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
OM947_08600	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
OM947_08605	COG1605	Chorismate mutase
OM947_08605	COG0077	Prephenate dehydratase
OM947_08610	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
OM947_08625	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
OM947_08630	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
OM947_08635	COG0583	DNA-binding transcription factor activity
OM947_08660	COG0840	transmembrane signaling receptor activity
OM947_08680	COG4191	Histidine kinase
OM947_08680	COG0784	Response regulator, receiver
OM947_08685	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
OM947_08705	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OM947_08715	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
OM947_08725	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
OM947_08740	COG1595	DNA-templated transcription, initiation
OM947_08790	COG2244	polysaccharide biosynthetic process
OM947_08820	COG2264	protein methyltransferase activity
OM947_08830	COG0438	transferase activity, transferring glycosyl groups
OM947_08845	COG1136	(ABC) transporter
OM947_08855	COG0477	Major facilitator Superfamily
OM947_08860	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OM947_08875	COG1253	flavin adenine dinucleotide binding
OM947_08885	COG0306	phosphate transporter
OM947_08910	COG0504	CTP synthase activity
OM947_08915	COG2877	3-deoxy-8-phosphooctulonate synthase activity
OM947_08925	COG0148	phosphopyruvate hydratase activity
OM947_08930	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
OM947_08940	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
OM947_08945	COG0585	pseudouridine synthase activity
OM947_08950	COG2840	Smr protein MutS2
OM947_08955	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
OM947_08960	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
OM947_08965	COG1238	metal cluster binding
OM947_08975	COG3737	Protein of unknown function (DUF498/DUF598)
OM947_08980	COG1534	Rna-binding protein
OM947_08985	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
OM947_08995	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
OM947_09000	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
OM947_09010	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
OM947_09015	COG1546	Belongs to the CinA family
OM947_09025	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
OM947_09030	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
OM947_09035	COG2137	regulation of response to DNA damage stimulus
OM947_09040	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
OM947_09045	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
OM947_09065	COG0583	DNA-binding transcription factor activity
OM947_09090	COG0351	phosphomethylpyrimidine kinase
OM947_09105	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
OM947_09110	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
OM947_09125	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OM947_09135	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
OM947_09140	COG3734	2-keto-3-deoxy-galactonokinase
OM947_09150	COG4948	Mandelate Racemase Muconate Lactonizing
OM947_09155	COG0800	Aldolase
OM947_09190	COG1501	Belongs to the glycosyl hydrolase 31 family
OM947_09200	COG1070	Carbohydrate kinase
OM947_09205	COG2115	Belongs to the xylose isomerase family
OM947_09210	COG0477	Major facilitator Superfamily
OM947_09225	COG0860	N-Acetylmuramoyl-L-alanine amidase
OM947_09230	COG1469	GTP cyclohydrolase I activity
OM947_09255	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
OM947_09260	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
OM947_09265	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
OM947_09270	COG0166	Belongs to the GPI family
OM947_09290	COG1472	Belongs to the glycosyl hydrolase 3 family
OM947_09300	COG3706	GGDEF domain
OM947_09300	COG2203	Gaf domain
OM947_09300	COG5001	Diguanylate cyclase
OM947_09300	COG4251	negative regulation of phosphorylation
OM947_09305	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
OM947_09310	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
OM947_09320	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
OM947_09325	COG0671	phosphoesterase, PA-phosphatase related
OM947_09335	COG1794	racemase activity, acting on amino acids and derivatives
OM947_09340	COG0697	spore germination
OM947_09345	COG0812	UDP-N-acetylmuramate dehydrogenase activity
OM947_09350	COG0167	dihydroorotate dehydrogenase activity
OM947_09365	COG1012	belongs to the aldehyde dehydrogenase family
OM947_09380	COG3328	transposase activity
OM947_09385	COG0366	Alpha amylase catalytic
OM947_09405	COG1082	Xylose isomerase domain protein TIM barrel
OM947_09415	COG2211	Major facilitator Superfamily
OM947_09430	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
OM947_09435	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
OM947_09450	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
OM947_09455	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OM947_09455	COG0072	phenylalanine-tRNA ligase activity
OM947_09505	COG0438	transferase activity, transferring glycosyl groups
OM947_09510	COG0438	transferase activity, transferring glycosyl groups
OM947_09520	COG0438	transferase activity, transferring glycosyl groups
OM947_09545	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OM947_09555	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OM947_09575	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
OM947_09585	COG1960	acyl-CoA dehydrogenase activity
OM947_09595	COG3040	lipid binding
OM947_09610	COG0322	excinuclease ABC activity
OM947_09625	COG4191	Histidine kinase
OM947_09625	COG0784	Response regulator, receiver
OM947_09645	COG1194	a g-specific adenine glycosylase
OM947_09650	COG0552	protein localization to endoplasmic reticulum
OM947_09660	COG3938	Belongs to the proline racemase family
OM947_09665	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OM947_09680	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OM947_09690	COG0006	proline dipeptidase activity
OM947_09705	COG0531	amino acid
OM947_09805	COG3328	transposase activity
OM947_09815	COG0840	transmembrane signaling receptor activity
OM947_09825	COG3328	transposase activity
OM947_09860	COG3210	domain, Protein
OM947_09865	COG3328	transposase activity
OM947_09870	COG0460	homoserine dehydrogenase
OM947_09870	COG0527	aspartate kinase activity
OM947_09905	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OM947_09910	COG0124	histidyl-tRNA synthetase
OM947_09920	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
OM947_09925	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
OM947_09930	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
OM947_09935	COG0131	Imidazoleglycerol-phosphate dehydratase
OM947_09935	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
OM947_09940	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
OM947_09945	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
OM947_09950	COG0107	imidazoleglycerol-phosphate synthase activity
OM947_09955	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
OM947_09955	COG0140	phosphoribosyl-ATP diphosphatase activity
OM947_09970	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
OM947_09975	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
OM947_09980	COG0235	Class ii aldolase
OM947_09985	COG0531	amino acid
OM947_09990	COG0531	amino acid
OM947_10000	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
OM947_10005	COG0277	FAD linked oxidase domain protein
OM947_10025	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
OM947_10070	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OM947_10075	COG2258	MOSC domain
OM947_10080	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
OM947_10085	COG0505	Belongs to the CarA family
OM947_10095	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
OM947_10100	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
OM947_10110	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
OM947_10130	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
OM947_10140	COG0784	Response regulator, receiver
OM947_10140	COG2198	Histidine kinase
OM947_10140	COG2205	protein histidine kinase activity
OM947_10145	COG0784	Response regulator, receiver
OM947_10145	COG2198	Histidine kinase
OM947_10145	COG2205	protein histidine kinase activity
OM947_10150	COG1024	Enoyl-CoA hydratase
OM947_10155	COG0318	PFAM AMP-dependent synthetase and ligase
OM947_10190	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OM947_10200	COG2201	protein-glutamate methylesterase activity
OM947_10205	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
OM947_10215	COG0840	transmembrane signaling receptor activity
OM947_10225	COG0835	chemotaxis
OM947_10235	COG0840	transmembrane signaling receptor activity
OM947_10240	COG0840	transmembrane signaling receptor activity
OM947_10245	COG0840	transmembrane signaling receptor activity
OM947_10250	COG0840	transmembrane signaling receptor activity
OM947_10255	COG0840	transmembrane signaling receptor activity
OM947_10270	COG0840	transmembrane signaling receptor activity
OM947_10275	COG0840	transmembrane signaling receptor activity
OM947_10280	COG0840	transmembrane signaling receptor activity
OM947_10285	COG0840	transmembrane signaling receptor activity
OM947_10295	COG0840	transmembrane signaling receptor activity
OM947_10310	COG0840	transmembrane signaling receptor activity
OM947_10315	COG0840	transmembrane signaling receptor activity
OM947_10325	COG0745	RESPONSE REGULATOR receiver
OM947_10335	COG0835	chemotaxis
OM947_10340	COG1192	Involved in chromosome partitioning
OM947_10345	COG1360	Flagellar Motor Protein
OM947_10350	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
OM947_10385	COG3328	transposase activity
OM947_10400	COG0643	Histidine kinase
OM947_10400	COG0784	Response regulator, receiver
OM947_10400	COG2198	Histidine kinase
OM947_10430	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
OM947_10455	COG3039	Transposase
OM947_10465	COG1684	flagellar biosynthetic protein fliR
OM947_10485	COG3190	flagellar
OM947_10535	COG1677	Flagellar hook-basal body complex protein FliE
OM947_10560	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
OM947_10590	COG1028	Short-chain dehydrogenase reductase Sdr
OM947_10595	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OM947_10615	COG2201	protein-glutamate methylesterase activity
OM947_10625	COG2197	response regulator
OM947_10650	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
OM947_10660	COG3039	Transposase
OM947_10665	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
OM947_10675	COG3951	Flagellar rod assembly protein muramidase FlgJ
OM947_10675	COG1705	Flagellar rod assembly protein muramidase FlgJ
OM947_10680	COG1706	bacterial-type flagellum-dependent cell motility
OM947_10685	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
OM947_10695	COG4787	bacterial-type flagellum-dependent cell motility
OM947_10705	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
OM947_10710	COG1558	bacterial-type flagellum-dependent cell motility
OM947_10720	COG0784	Response regulator, receiver
OM947_10720	COG0835	chemotaxis
OM947_10740	COG5002	protein histidine kinase activity
OM947_10750	COG4585	Histidine kinase
OM947_10770	COG2915	High frequency lysogenization protein hflD homolog
OM947_10775	COG0482	sulfurtransferase activity
OM947_10795	COG0542	response to heat
OM947_10805	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
OM947_10815	COG0492	ferredoxin-NADP+ reductase activity
OM947_10820	COG1674	ftsk spoiiie
OM947_10830	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
OM947_10840	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
OM947_10845	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
OM947_10850	COG0183	Belongs to the thiolase family
OM947_10855	COG1024	Enoyl-CoA hydratase
OM947_10855	COG1250	3-hydroxyacyl-CoA dehydrogenase
OM947_10870	COG0820	rRNA (adenine-C2-)-methyltransferase activity
OM947_10890	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
OM947_10895	COG1160	GTP binding
OM947_10900	COG0303	'Molybdopterin
OM947_10905	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
OM947_10940	COG0708	Exodeoxyribonuclease III
OM947_10950	COG0303	'Molybdopterin
OM947_10955	COG0746	molybdenum cofactor guanylyltransferase activity
OM947_10980	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
OM947_10980	COG1648	precorrin-2 dehydrogenase activity
OM947_10990	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OM947_10995	COG2223	nitrite transmembrane transporter activity
OM947_11000	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OM947_11010	COG0243	molybdopterin cofactor binding
OM947_11030	COG3685	Protein conserved in bacteria
OM947_11050	COG5001	Diguanylate cyclase
OM947_11060	COG4566	intracellular signal transduction
OM947_11110	COG3328	transposase activity
OM947_11135	COG3328	transposase activity
OM947_11145	COG2226	methyltransferase
OM947_11145	COG1073	alpha beta
OM947_11160	COG0363	glucosamine-6-phosphate deaminase activity
OM947_11200	COG1309	transcriptional regulator
OM947_11215	COG2154	pterin-4-alpha-carbinolamine dehydratase
OM947_11225	COG0428	transporter
OM947_11230	COG3064	Membrane
OM947_11240	COG1530	ribonuclease E activity
OM947_11245	COG3039	Transposase
OM947_11255	COG1054	Belongs to the UPF0176 family
OM947_11275	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
OM947_11300	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
OM947_11305	COG0322	excinuclease ABC activity
OM947_11315	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
OM947_11320	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
OM947_11325	COG1663	tetraacyldisaccharide 4'-kinase activity
OM947_11330	COG1132	(ABC) transporter
OM947_11340	COG0811	peptide transport
OM947_11355	COG1136	(ABC) transporter
OM947_11360	COG4591	ABC-type transport system involved in lipoprotein release permease component
OM947_11370	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
OM947_11375	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
OM947_11390	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
OM947_11405	COG0354	folic acid binding
OM947_11415	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
OM947_11420	COG0837	glucose binding
OM947_11425	COG0363	glucosamine-6-phosphate deaminase activity
OM947_11430	COG0129	dihydroxy-acid dehydratase activity
OM947_11435	COG0800	Aldolase
OM947_11500	COG0784	Response regulator, receiver
OM947_11500	COG2205	protein histidine kinase activity
OM947_11505	COG2183	response to ionizing radiation
OM947_11515	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OM947_11515	COG0723	plastoquinol--plastocyanin reductase activity
OM947_11530	COG3243	poly(R)-hydroxyalkanoic acid synthase
OM947_11540	COG1183	phosphatidylcholine synthase activity
OM947_11545	COG1028	Short-chain dehydrogenase reductase Sdr
OM947_11560	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
OM947_11575	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
OM947_11590	COG1914	H( )-stimulated, divalent metal cation uptake system
OM947_11610	COG2814	Major facilitator Superfamily
OM947_11625	COG1335	isochorismatase
OM947_11640	COG2197	response regulator
OM947_11675	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
OM947_11680	COG3002	Belongs to the UPF0753 family
OM947_11690	COG0604	alcohol dehydrogenase
OM947_11695	COG3384	dioxygenase
OM947_11705	COG2801	Transposase and inactivated derivatives
OM947_11720	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
OM947_11735	COG0583	DNA-binding transcription factor activity
OM947_11780	COG0518	GMP synthase (glutamine-hydrolyzing) activity
OM947_11780	COG0519	Catalyzes the synthesis of GMP from XMP
OM947_11790	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
OM947_11800	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
OM947_11800	COG0475	glutathione-regulated potassium exporter activity
OM947_11805	COG1210	Utp--glucose-1-phosphate uridylyltransferase
OM947_11815	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
OM947_11820	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
OM947_11830	COG0776	regulation of translation
OM947_11835	COG0539	negative regulation of cytoplasmic translation
OM947_11840	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
OM947_11855	COG2957	Belongs to the agmatine deiminase family
OM947_11860	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OM947_11885	COG0395	ABC-type sugar transport system, permease component
OM947_11890	COG1175	transmembrane transport
OM947_11920	COG2350	Protein conserved in bacteria
OM947_11925	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
OM947_11930	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
OM947_11935	COG1187	pseudouridine synthase activity
OM947_11950	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OM947_11955	COG0436	Aminotransferase
OM947_11960	COG4133	protoheme IX ABC transporter activity
OM947_11980	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
OM947_12005	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OM947_12015	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
OM947_12020	COG4988	ABC transporter
OM947_12030	COG1294	oxidase, subunit
OM947_12060	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
OM947_12065	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
OM947_12075	COG0165	Argininosuccinate lyase
OM947_12080	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
OM947_12090	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
OM947_12095	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
OM947_12105	COG0137	argininosuccinate synthase activity
OM947_12110	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
OM947_12120	COG0215	cysteine-tRNA ligase activity
OM947_12125	COG2166	iron-sulfur cluster assembly
OM947_12145	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
OM947_12150	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
OM947_12175	COG4302	ethanolamine ammonia-lyase activity
OM947_12205	COG3039	Transposase
OM947_12230	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
OM947_12235	COG0402	S-adenosylhomocysteine deaminase activity
OM947_12245	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
OM947_12250	COG1509	lysine 2,3-aminomutase activity
OM947_12255	COG3300	MHYT domain
OM947_12255	COG5001	Diguanylate cyclase
OM947_12270	COG0483	inositol monophosphate 1-phosphatase activity
OM947_12275	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
OM947_12290	COG0488	(ABC) transporter
OM947_12295	COG0513	Belongs to the DEAD box helicase family
OM947_12300	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
OM947_12305	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
OM947_12320	COG0625	glutathione transferase activity
OM947_12330	COG4681	YaeQ
OM947_12335	COG2081	HI0933 family
OM947_12345	COG0501	Belongs to the peptidase M48B family
OM947_12350	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OM947_12355	COG1028	Short-chain dehydrogenase reductase Sdr
OM947_12380	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
OM947_12385	COG0860	N-Acetylmuramoyl-L-alanine amidase
OM947_12390	COG0802	atpase or kinase
OM947_12395	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
OM947_12395	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
OM947_12400	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
OM947_12405	COG1570	exodeoxyribonuclease VII activity
OM947_12415	COG1262	PFAM Formylglycine-generating sulfatase enzyme
OM947_12460	COG0835	chemotaxis
OM947_12465	COG0840	transmembrane signaling receptor activity
OM947_12470	COG2094	Belongs to the DNA glycosylase MPG family
OM947_12475	COG1201	RNA secondary structure unwinding
OM947_12495	COG2969	positive regulation of protein catabolic process
OM947_12500	COG0625	glutathione transferase activity
OM947_12505	COG2857	Cytochrome c1
OM947_12510	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
OM947_12515	COG0723	plastoquinol--plastocyanin reductase activity
OM947_12520	COG0741	lytic transglycosylase activity
OM947_12535	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
OM947_12540	COG1702	phosphate starvation-inducible protein PhoH
OM947_12550	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
OM947_12560	COG4535	Mg2 and Co2 transporter CorC
OM947_12575	COG1012	belongs to the aldehyde dehydrogenase family
OM947_12580	COG1177	transmembrane transport
OM947_12585	COG1176	ABC-type spermidine putrescine transport system, permease component I
OM947_12590	COG3842	ATPase activity
OM947_12610	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
OM947_12630	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
OM947_12635	COG0174	glutamine synthetase
OM947_12640	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OM947_12650	COG2703	oxygen carrier activity
OM947_12655	COG0477	Major facilitator Superfamily
OM947_12665	COG0243	molybdopterin cofactor binding
OM947_12670	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
OM947_12675	COG2223	nitrite transmembrane transporter activity
OM947_12685	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
OM947_12695	COG2733	membrane
OM947_12700	COG2205	protein histidine kinase activity
OM947_12700	COG5002	protein histidine kinase activity
OM947_12700	COG0784	Response regulator, receiver
OM947_12710	COG0477	Major facilitator Superfamily
OM947_12715	COG0840	transmembrane signaling receptor activity
OM947_12745	COG2902	Dehydrogenase
OM947_12755	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OM947_12760	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OM947_12765	COG1609	Transcriptional regulator
OM947_12770	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
OM947_12770	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
OM947_12775	COG1105	Belongs to the carbohydrate kinase PfkB family
OM947_12780	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OM947_12780	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OM947_12800	COG3328	transposase activity
OM947_12820	COG3328	transposase activity
OM947_12825	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OM947_12835	COG1862	Preprotein translocase
OM947_12840	COG0343	queuine tRNA-ribosyltransferase activity
OM947_12845	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
OM947_12880	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
OM947_12885	COG3291	Pkd domain containing protein
OM947_12890	COG0405	Gamma-glutamyltransferase
OM947_12895	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
OM947_12905	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
OM947_12910	COG0742	ribosomal rna small subunit methyltransferase
OM947_12915	COG0326	Molecular chaperone. Has ATPase activity
OM947_12965	COG3702	type iv secretory pathway
OM947_12985	COG2948	multi-organism process
OM947_13005	COG3505	Type IV secretory pathway VirD4
OM947_13020	COG0556	nucleotide-excision repair
OM947_13185	COG3179	chitinase
OM947_13240	COG4695	Portal protein
OM947_13315	COG3275	phosphorelay sensor kinase activity
OM947_13320	COG1611	Belongs to the LOG family
OM947_13330	COG2095	MarC family integral membrane protein
OM947_13340	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
OM947_13375	COG1185	polyribonucleotide nucleotidyltransferase activity
OM947_13380	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
OM947_13385	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
OM947_13390	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
OM947_13395	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
OM947_13400	COG0195	Participates in both transcription termination and antitermination
OM947_13405	COG0779	Required for maturation of 30S ribosomal subunits
OM947_13415	COG1007	ATP synthesis coupled electron transport
OM947_13440	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OM947_13445	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
OM947_13455	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
OM947_13460	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
OM947_13465	COG0649	NAD binding
OM947_13470	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OM947_13475	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OM947_13480	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OM947_13495	COG0149	triose-phosphate isomerase activity
OM947_13500	COG4221	oxidoreductase activity
OM947_13530	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OM947_13535	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
OM947_13540	COG0159	tryptophan synthase activity
OM947_13550	COG0133	tryptophan synthase activity
OM947_13560	COG0135	phosphoribosylanthranilate isomerase activity
OM947_13565	COG0101	tRNA pseudouridine synthase activity
OM947_13580	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
OM947_13585	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OM947_13590	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
OM947_13595	COG2890	protein-(glutamine-N5) methyltransferase activity
OM947_13605	COG0688	phosphatidylethanolamine metabolic process
OM947_13615	COG0433	COG0433 Predicted ATPase
OM947_13640	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
OM947_13645	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
OM947_13670	COG0717	Belongs to the dCTP deaminase family
OM947_13675	COG0489	protein tyrosine kinase activity
OM947_13705	COG3590	peptidase
OM947_13730	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OM947_13735	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OM947_13740	COG2311	Membrane
OM947_13745	COG1047	Peptidyl-prolyl cis-trans
OM947_13750	COG0791	NLP P60 protein
OM947_13755	COG0791	NLP P60 protein
OM947_13765	COG4106	trans-aconitate 2-methyltransferase activity
OM947_13770	COG1301	dicarboxylic acid transport
OM947_13775	COG1785	Belongs to the alkaline phosphatase family
OM947_13780	COG0037	tRNA processing
OM947_13785	COG1722	exodeoxyribonuclease VII activity
OM947_13790	COG0142	geranyltranstransferase activity
OM947_13795	COG4104	PAAR repeat-containing protein
OM947_13805	COG0312	modulator of DNA gyrase
OM947_13810	COG3028	Belongs to the UPF0307 family
OM947_13815	COG0312	modulator of DNA gyrase
OM947_13825	COG3164	Protein of unknown function
OM947_13835	COG0424	maF-like protein
OM947_13840	COG2968	Membrane
OM947_13855	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
OM947_13870	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
OM947_13885	COG0495	leucyl-tRNA aminoacylation
OM947_13895	COG3118	belongs to the thioredoxin family
OM947_13920	COG2155	Conserved Protein
OM947_13970	COG1132	(ABC) transporter
OM947_14000	COG0745	RESPONSE REGULATOR receiver
OM947_14005	COG5002	protein histidine kinase activity
OM947_14005	COG5000	phosphorelay sensor kinase activity
OM947_14010	COG0475	glutathione-regulated potassium exporter activity
OM947_14020	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
OM947_14040	COG1187	pseudouridine synthase activity
OM947_14045	COG5002	protein histidine kinase activity
OM947_14045	COG5001	Diguanylate cyclase
OM947_14055	COG1595	DNA-templated transcription, initiation
OM947_14170	COG0667	Aldo Keto reductase
OM947_14175	COG2814	Major facilitator Superfamily
OM947_14180	COG0583	DNA-binding transcription factor activity
OM947_14190	COG2207	Transcriptional regulator
OM947_14200	COG1309	transcriptional regulator
OM947_14210	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OM947_14225	COG0735	belongs to the Fur family
OM947_14230	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OM947_14255	COG4452	Inner membrane protein CreD
OM947_14275	COG0745	RESPONSE REGULATOR receiver
OM947_14280	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
OM947_14295	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
OM947_14305	COG0643	Histidine kinase
OM947_14305	COG2198	Histidine kinase
OM947_14310	COG0840	transmembrane signaling receptor activity
OM947_14315	COG0835	chemotaxis
OM947_14320	COG2202	Pas domain
OM947_14320	COG2199	diguanylate cyclase activity
OM947_14320	COG2200	EAL domain
OM947_14325	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
OM947_14330	COG2201	protein-glutamate methylesterase activity
OM947_14340	COG3590	peptidase
OM947_14355	COG1515	deoxyribonuclease V activity
OM947_14365	COG1741	Belongs to the pirin family
OM947_14380	COG1741	Belongs to the pirin family
OM947_14385	COG1966	Carbon starvation protein
OM947_14390	COG2879	small protein
OM947_14425	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
OM947_14430	COG1529	Aldehyde oxidase and xanthine dehydrogenase
OM947_14435	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
OM947_14440	COG2080	2 iron, 2 sulfur cluster binding
OM947_14445	COG1028	Short-chain dehydrogenase reductase Sdr
OM947_14445	COG3321	synthase
OM947_14445	COG0604	alcohol dehydrogenase
OM947_14450	COG5001	Diguanylate cyclase
OM947_14450	COG3706	GGDEF domain
OM947_14450	COG4251	negative regulation of phosphorylation
OM947_14450	COG2203	Gaf domain
OM947_14455	COG0629	single-stranded DNA binding
OM947_14460	COG0142	geranyltranstransferase activity
OM947_14470	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
OM947_14485	COG0527	aspartate kinase activity
OM947_14490	COG0384	phenazine biosynthesis protein PhzF
OM947_14495	COG0384	phenazine biosynthesis protein PhzF
OM947_14505	COG1764	response to oxidative stress
OM947_14510	COG0540	Belongs to the ATCase OTCase family
OM947_14515	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
OM947_14520	COG1678	Uncharacterized ACR, COG1678
OM947_14525	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
OM947_14530	COG0519	Catalyzes the synthesis of GMP from XMP
OM947_14555	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
OM947_14570	COG0739	heme binding
OM947_14590	COG0693	protein deglycase activity
OM947_14600	COG1959	2 iron, 2 sulfur cluster binding
OM947_14605	COG0719	Fe-S assembly protein
OM947_14610	COG0396	ATPase activity
OM947_14615	COG0719	Fe-S assembly protein
OM947_14620	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
OM947_14625	COG0456	acetyltransferase
OM947_14630	COG2146	nitrite reductase [NAD(P)H] activity
OM947_14635	COG4774	siderophore transport
OM947_14640	COG3128	pkhd-type hydroxylase
OM947_14665	COG3328	transposase activity
OM947_14670	COG1477	protein flavinylation
OM947_14675	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
OM947_14685	COG1555	photosystem II stabilization
OM947_14705	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
OM947_14715	COG0628	permease
OM947_14725	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
OM947_14740	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
OM947_14760	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
OM947_14765	COG0271	Belongs to the BolA IbaG family
OM947_14775	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
OM947_14785	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
OM947_14790	COG1137	ATPase activity
OM947_14805	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
OM947_14810	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
OM947_14815	COG1660	Displays ATPase and GTPase activities
OM947_14825	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
OM947_14830	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
OM947_14840	COG2239	Acts as a magnesium transporter
OM947_14850	COG1294	oxidase, subunit
OM947_14860	COG1271	oxidase subunit
OM947_14870	COG1113	amino acid transport
OM947_14895	COG2197	response regulator
OM947_14900	COG0531	amino acid
OM947_14965	COG2814	Major facilitator Superfamily
OM947_14970	COG0754	glutathionylspermidine amidase activity
OM947_14995	COG1842	Phage shock protein A
OM947_15005	COG0259	pyridoxamine-phosphate oxidase activity
OM947_15010	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
OM947_15015	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
OM947_15025	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
OM947_15030	COG2814	Major facilitator Superfamily
OM947_15055	COG2198	Histidine kinase
OM947_15055	COG2205	protein histidine kinase activity
OM947_15055	COG0784	Response regulator, receiver
OM947_15060	COG2353	YceI-like domain
OM947_15080	COG1760	l-serine dehydratase
OM947_15090	COG0527	aspartate kinase activity
OM947_15090	COG0460	homoserine dehydrogenase
OM947_15095	COG0626	cystathionine gamma-synthase activity
OM947_15100	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OM947_15105	COG0739	heme binding
OM947_15110	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
OM947_15115	COG1272	protein, Hemolysin III
OM947_15120	COG2982	Protein involved in outer membrane biogenesis
OM947_15125	COG0516	GMP reductase activity
OM947_15125	COG0517	IMP dehydrogenase activity
OM947_15130	COG0463	Glycosyl transferase, family 2
OM947_15135	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OM947_15140	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
OM947_15150	COG4771	TonB-dependent receptor
OM947_15155	COG1309	transcriptional regulator
OM947_15165	COG1960	acyl-CoA dehydrogenase activity
OM947_15190	COG3328	transposase activity
OM947_15210	COG0509	glycine decarboxylation via glycine cleavage system
OM947_15215	COG0404	The glycine cleavage system catalyzes the degradation of glycine
OM947_15225	COG0330	HflC and HflK could
OM947_15230	COG1742	UPF0060 membrane protein
OM947_15235	COG3956	TIGRFAM MazG family protein
OM947_15245	COG0494	nUDIX hydrolase
OM947_15255	COG1385	rRNA (uridine-N3-)-methyltransferase activity
OM947_15260	COG0837	glucose binding
OM947_15285	COG1388	LysM domain
OM947_15285	COG3858	chitin binding
OM947_15290	COG3525	Glycosyl hydrolase, family 20, catalytic domain
OM947_15300	COG1472	Belongs to the glycosyl hydrolase 3 family
OM947_15310	COG3537	Alpha-1,2-mannosidase
OM947_15345	COG3142	Participates in the control of copper homeostasis
OM947_15350	COG1446	asparaginase
OM947_15375	COG2198	Histidine kinase
OM947_15375	COG0784	Response regulator, receiver
OM947_15375	COG0643	Histidine kinase
OM947_15380	COG0840	transmembrane signaling receptor activity
OM947_15385	COG0835	chemotaxis
OM947_15400	COG0189	ligase activity
OM947_15410	COG1397	ADP-ribosylglycohydrolase
OM947_15420	COG1199	ATP-dependent helicase activity
OM947_15430	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OM947_15435	COG1215	transferase activity, transferring glycosyl groups
OM947_15445	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
OM947_15455	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
OM947_15460	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
OM947_15465	COG0535	radical SAM domain protein
OM947_15470	COG0535	radical SAM domain protein
OM947_15485	COG0837	glucose binding
OM947_15495	COG3328	transposase activity
OM947_15505	COG1643	Atp-dependent helicase
OM947_15510	COG0783	Belongs to the Dps family
OM947_15515	COG0514	ATP-dependent DNA helicase (RecQ)
OM947_15555	COG0840	transmembrane signaling receptor activity
OM947_15575	COG3920	Histidine kinase
OM947_15580	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
OM947_15590	COG0602	queuosine metabolic process
OM947_15600	COG2885	chlorophyll binding
OM947_15605	COG0823	Involved in the tonB-independent uptake of proteins
OM947_15615	COG0848	biopolymer transport protein
OM947_15625	COG0824	Thioesterase
OM947_15630	COG2255	four-way junction helicase activity
OM947_15640	COG3158	transport of potassium into the cell
OM947_15645	COG0632	four-way junction helicase activity
OM947_15650	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
OM947_15655	COG0217	transcriptional regulatory protein
OM947_15670	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
OM947_15685	COG0477	Major facilitator Superfamily
OM947_15705	COG0657	acetylesterase activity
OM947_15705	COG2755	lipolytic protein G-D-S-L family
OM947_15725	COG0488	(ABC) transporter
OM947_15755	COG4651	solute:proton antiporter activity
OM947_15755	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
OM947_15770	COG3328	transposase activity
OM947_15790	COG4772	TonB-dependent receptor
OM947_15800	COG4264	IucA IucC family
OM947_15815	COG0019	diaminopimelate decarboxylase activity
OM947_15845	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
OM947_15855	COG1492	cobalamin metabolic process
OM947_15865	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
OM947_15890	COG4206	TonB-dependent receptor
OM947_15900	COG0542	response to heat
OM947_15945	COG1877	trehalose-phosphatase activity
OM947_15950	COG3387	PFAM Glycoside hydrolase 15-related
OM947_15970	COG0840	transmembrane signaling receptor activity
OM947_15975	COG3011	Protein conserved in bacteria
OM947_15990	COG0564	pseudouridine synthase activity
OM947_15995	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
OM947_16005	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
OM947_16005	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OM947_16015	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
OM947_16020	COG0045	succinate-CoA ligase (ADP-forming) activity
OM947_16065	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
OM947_16070	COG0237	dephospho-CoA kinase activity
OM947_16075	COG3328	transposase activity
OM947_16105	COG0745	RESPONSE REGULATOR receiver
OM947_16115	COG0189	ligase activity
OM947_16145	COG2801	Transposase and inactivated derivatives
OM947_16160	COG2003	Belongs to the UPF0758 family
OM947_16180	COG3328	transposase activity
OM947_16225	COG2022	thiamine diphosphate biosynthetic process
OM947_16230	COG0220	tRNA (guanine-N7-)-methyltransferase activity
OM947_16235	COG0471	metal ion transport
OM947_16235	COG3273	potassium ion transport
OM947_16260	COG1970	mechanosensitive ion channel activity
OM947_16270	COG1609	Transcriptional regulator
OM947_16280	COG3250	beta-galactosidase activity
OM947_16285	COG4948	Mandelate Racemase Muconate Lactonizing
OM947_16295	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OM947_16305	COG0308	aminopeptidase N
OM947_16310	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OM947_16320	COG0529	Catalyzes the synthesis of activated sulfate
OM947_16320	COG2895	sulfate adenylyltransferase (ATP) activity
OM947_16325	COG0175	sulfate reduction
OM947_16330	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
OM947_16335	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OM947_16340	COG0175	sulfate reduction
OM947_16360	COG2205	protein histidine kinase activity
OM947_16360	COG0784	Response regulator, receiver
OM947_16360	COG2198	Histidine kinase
OM947_16375	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
OM947_16375	COG1648	precorrin-2 dehydrogenase activity
OM947_16390	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
OM947_16395	COG3588	fructose-bisphosphate aldolase
OM947_16410	COG0126	phosphoglycerate kinase activity
OM947_16440	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
OM947_16450	COG3047	cAMP biosynthetic process
OM947_16465	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OM947_16465	COG3453	Protein conserved in bacteria
OM947_16470	COG0725	ABC transporter, periplasmic molybdate-binding protein
OM947_16475	COG4149	molybdate abc transporter
OM947_16480	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
OM947_16500	COG0642	Histidine kinase
OM947_16525	COG1022	Amp-dependent synthetase and ligase
OM947_16550	COG1376	ErfK ybiS ycfS ynhG family protein
OM947_16555	COG0739	heme binding
OM947_16560	COG4773	Receptor
OM947_16575	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
OM947_16580	COG1301	dicarboxylic acid transport
OM947_16590	COG2304	oxidoreductase activity
OM947_16610	COG0714	Associated with various cellular activities
OM947_16640	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
OM947_16660	COG1957	nucleoside hydrolase
OM947_16665	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
OM947_16675	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
OM947_16690	COG1561	YicC-like family, N-terminal region
OM947_16695	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
OM947_16705	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
OM947_16710	COG0635	Involved in the biosynthesis of porphyrin-containing compound
OM947_16725	COG0006	proline dipeptidase activity
OM947_16735	COG0006	proline dipeptidase activity
OM947_16740	COG3079	Belongs to the UPF0149 family
OM947_16760	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
OM947_16780	COG2912	Transglutaminase-like superfamily
OM947_16785	COG1773	rubredoxin
OM947_16790	COG0352	thiamine-phosphate diphosphorylase activity
OM947_16810	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
OM947_16820	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
OM947_16825	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
OM947_16855	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
OM947_16860	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OM947_16865	COG1028	Short-chain dehydrogenase reductase Sdr
OM947_16875	COG0671	phosphoesterase, PA-phosphatase related
OM947_16885	COG3781	membrane
OM947_16895	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
OM947_16900	COG0563	adenylate kinase activity
OM947_16915	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
OM947_16925	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
OM947_16945	COG3710	Transcriptional regulator
OM947_16950	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
OM947_16960	COG0840	transmembrane signaling receptor activity
OM947_16965	COG0405	Gamma-glutamyltransferase
OM947_16970	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
OM947_16990	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
OM947_16995	COG0473	3-isopropylmalate dehydrogenase activity
OM947_17000	COG0066	3-isopropylmalate dehydratase activity
OM947_17005	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
OM947_17025	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
OM947_17030	COG1538	Outer membrane efflux protein
OM947_17035	COG1519	Transferase
OM947_17040	COG1560	Kdo2-lipid A biosynthetic process
OM947_17065	COG0281	malic enzyme
OM947_17065	COG0280	phosphate acetyltransferase
OM947_17070	COG1301	dicarboxylic acid transport
OM947_17095	COG0583	DNA-binding transcription factor activity
OM947_17100	COG0667	Aldo Keto reductase
OM947_17115	COG2197	response regulator
OM947_17125	COG0642	Histidine kinase
OM947_17140	COG2851	Citrate transporter
OM947_17145	COG1028	Short-chain dehydrogenase reductase Sdr
OM947_17150	COG1609	Transcriptional regulator
OM947_17155	COG2211	Major facilitator Superfamily
OM947_17180	COG1162	GTPase activity
OM947_17185	COG0436	Aminotransferase
OM947_17200	COG0726	polysaccharide deacetylase
OM947_17205	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
OM947_17220	COG3964	amidohydrolase
OM947_17225	COG0402	S-adenosylhomocysteine deaminase activity
OM947_17250	COG3328	transposase activity
OM947_17260	COG1307	EDD domain protein, DegV family
OM947_17275	COG2801	Transposase and inactivated derivatives
OM947_17285	COG3791	Glutathione-dependent formaldehyde-activating
OM947_17315	COG2205	protein histidine kinase activity
OM947_17330	COG0218	Necessary for normal cell division and for the maintenance of normal septation
OM947_17345	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
OM947_17355	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
OM947_17360	COG1012	belongs to the aldehyde dehydrogenase family
OM947_17365	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
OM947_17390	COG1183	phosphatidylcholine synthase activity
OM947_17400	COG0442	prolyl-tRNA aminoacylation
OM947_17415	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
OM947_17420	COG1127	ABC transporter
OM947_17425	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
OM947_17425	COG3218	ABC-type transport auxiliary lipoprotein component
OM947_17455	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OM947_17460	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
OM947_17460	COG0662	Cupin 2, conserved barrel domain protein
OM947_17490	COG2086	electron transfer activity
OM947_17505	COG0546	phosphoglycolate phosphatase activity
OM947_17505	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
OM947_17510	COG0277	FAD linked oxidase domain protein
OM947_17520	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OM947_17545	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OM947_17550	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
OM947_17555	COG0438	transferase activity, transferring glycosyl groups
OM947_17575	COG0438	transferase activity, transferring glycosyl groups
OM947_17580	COG0626	cystathionine gamma-synthase activity
OM947_17610	COG0625	glutathione transferase activity
OM947_17620	COG0513	Belongs to the DEAD box helicase family
OM947_17625	COG0720	synthase
OM947_17635	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
OM947_17645	COG1956	GAF domain-containing protein
OM947_17660	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OM947_17665	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
OM947_17675	COG4991	sh3 domain protein
OM947_17685	COG0339	signal peptide processing
OM947_17700	COG2132	Multicopper oxidase
OM947_17735	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
OM947_17740	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OM947_17745	COG1136	(ABC) transporter
OM947_17750	COG1136	(ABC) transporter
OM947_17750	COG0577	efflux transmembrane transporter activity
OM947_17770	COG4191	Histidine kinase
OM947_17775	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
OM947_17800	COG0355	proton-transporting ATP synthase activity, rotational mechanism
OM947_17805	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
OM947_17810	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
OM947_17815	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
OM947_17820	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
OM947_17835	COG0356	it plays a direct role in the translocation of protons across the membrane
OM947_17855	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OM947_17865	COG0508	dehydrogenase complex catalyzes the overall conversion of
OM947_17900	COG2011	ABC-type metal ion transport system permease component
OM947_17905	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
OM947_17910	COG0697	spore germination
OM947_17915	COG1666	GTP binding
OM947_17925	COG5002	protein histidine kinase activity
OM947_17925	COG0784	Response regulator, receiver
OM947_17925	COG2198	Histidine kinase
OM947_17950	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OM947_17955	COG1187	pseudouridine synthase activity
OM947_17960	COG2813	Specifically methylates the guanine in position
OM947_17975	COG3039	Transposase
OM947_18005	COG2202	Pas domain
OM947_18005	COG2205	protein histidine kinase activity
OM947_18025	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
OM947_18030	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OM947_18085	COG0842	Transport permease protein
OM947_18090	COG1131	(ABC) transporter
OM947_18095	COG0025	NhaP-type Na H and K H
OM947_18100	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
OM947_18105	COG1573	uracil-dna glycosylase
OM947_18115	COG3384	dioxygenase
OM947_18125	COG0583	DNA-binding transcription factor activity
OM947_18135	COG0667	Aldo Keto reductase
OM947_18150	COG3590	peptidase
OM947_18165	COG0531	amino acid
OM947_18180	COG2972	Histidine kinase
OM947_18195	COG3685	Protein conserved in bacteria
OM947_18200	COG3546	catalase activity
OM947_18250	COG1271	oxidase subunit
OM947_18255	COG1294	oxidase, subunit
OM947_18270	COG1028	Short-chain dehydrogenase reductase Sdr
OM947_18290	COG1063	alcohol dehydrogenase
OM947_18300	COG3328	transposase activity
OM947_18370	COG0251	oxidation-reduction process
OM947_18400	COG0659	secondary active sulfate transmembrane transporter activity
OM947_18405	COG0038	chloride channel
OM947_18415	COG0024	Methionine aminopeptidase
OM947_18430	COG1028	Short-chain dehydrogenase reductase Sdr
OM947_18450	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OM947_18455	COG1490	D-aminoacyl-tRNA deacylase activity
OM947_18460	COG1560	Kdo2-lipid A biosynthetic process
OM947_18505	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
OM947_18505	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
OM947_18510	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
OM947_18515	COG0242	peptide deformylase activity
OM947_18520	COG1652	LysM domain
OM947_18525	COG0758	DNA mediated transformation
OM947_18545	COG1754	DNA topoisomerase type I activity
OM947_18545	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OM947_18550	COG0009	L-threonylcarbamoyladenylate synthase
OM947_18565	COG1028	Short-chain dehydrogenase reductase Sdr
OM947_18575	COG0616	signal peptide processing
OM947_18580	COG0534	Mate efflux family protein
OM947_18600	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
OM947_18605	COG0625	glutathione transferase activity
OM947_18620	COG1252	NADH dehydrogenase
OM947_18625	COG2860	membrane
OM947_18630	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OM947_18635	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
OM947_18640	COG2201	protein-glutamate methylesterase activity
OM947_18645	COG2177	Part of the ABC transporter FtsEX involved in
OM947_18650	COG2884	Cell division ATP-binding protein ftsE
OM947_18655	COG0513	Belongs to the DEAD box helicase family
OM947_18660	COG3118	belongs to the thioredoxin family
OM947_18665	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
OM947_18675	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
OM947_18700	COG1652	LysM domain
OM947_18705	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
OM947_18705	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
OM947_18710	COG1473	amidohydrolase
OM947_18715	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OM947_18720	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OM947_18740	COG5383	Protein conserved in bacteria
OM947_18780	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
OM947_18785	COG3023	N-Acetylmuramoyl-L-alanine amidase
OM947_18805	COG0531	amino acid
OM947_18825	COG3328	transposase activity
OM947_18835	COG2133	pyrroloquinoline quinone binding
OM947_18845	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
OM947_18850	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
OM947_18865	COG1610	YqeY-like protein
OM947_18870	COG1295	ribonuclease BN
OM947_18875	COG0358	DNA primase activity
OM947_18890	COG0109	protoheme IX farnesyltransferase activity
OM947_18920	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
OM947_18935	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
OM947_18975	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
OM947_18980	COG0739	heme binding
OM947_18985	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
OM947_18995	COG2223	nitrite transmembrane transporter activity
OM947_19000	COG0708	Exodeoxyribonuclease III
OM947_19005	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
OM947_19015	COG1192	Involved in chromosome partitioning
OM947_19020	COG1475	DNA binding
OM947_19035	COG0463	Glycosyl transferase, family 2
OM947_19055	COG0756	dUTP diphosphatase activity
OM947_19060	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
OM947_19065	COG2003	Belongs to the UPF0758 family
OM947_19070	COG0018	arginyl-trna synthetase
OM947_19085	COG4221	oxidoreductase activity
OM947_19090	COG2755	lipolytic protein G-D-S-L family
OM947_19090	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
OM947_19100	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OM947_19105	COG1166	arginine decarboxylase activity
OM947_19110	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
OM947_19130	COG3291	Pkd domain containing protein
OM947_19130	COG3525	Glycosyl hydrolase, family 20, catalytic domain
OM947_19145	COG0606	chelatase, subunit chli
OM947_19160	COG4943	cyclic-guanylate-specific phosphodiesterase activity
OM947_19185	COG1690	Belongs to the RtcB family
OM947_19225	COG1090	epimerase
OM947_19235	COG0642	Histidine kinase
OM947_19255	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OM947_19280	COG1011	Hydrolase
OM947_19285	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
OM947_19300	COG0753	catalase activity
OM947_19315	COG2197	response regulator
OM947_19320	COG4585	Histidine kinase
OM947_19325	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OM947_19330	COG1136	(ABC) transporter
OM947_19355	COG0697	spore germination
OM947_19380	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OM947_19385	COG0180	Tryptophanyl-tRNA synthetase
OM947_19390	COG3237	CsbD-like
OM947_19430	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
OM947_19445	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
OM947_19450	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
OM947_19450	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
OM947_19460	COG3228	Belongs to the MtfA family
OM947_19490	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OM947_19530	COG3328	transposase activity
OM947_19545	COG1199	ATP-dependent helicase activity
OM947_19560	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
OM947_19650	COG4555	ABC transporter
OM947_19660	COG1476	TRANSCRIPTIONal
OM947_19680	COG1230	cation diffusion facilitator family transporter
OM947_19685	COG0543	2 iron, 2 sulfur cluster binding
OM947_19685	COG0633	Ferredoxin
OM947_19690	COG1131	(ABC) transporter
OM947_19695	COG0842	Transport permease protein
OM947_19700	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
OM947_19725	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OM947_19745	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OM947_19750	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OM947_19765	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OM947_19765	COG1042	CoA-binding domain protein
OM947_19765	COG0045	succinate-CoA ligase (ADP-forming) activity
OM947_19770	COG2239	Acts as a magnesium transporter
OM947_19790	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
OM947_19795	COG3387	PFAM Glycoside hydrolase 15-related
OM947_19810	COG3100	YcgL domain-containing protein
OM947_19815	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
OM947_19825	COG0463	Glycosyl transferase, family 2
OM947_19835	COG1028	Short-chain dehydrogenase reductase Sdr
OM947_19890	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OM947_19925	COG0408	coproporphyrinogen oxidase activity
OM947_19960	COG0515	serine threonine protein kinase
OM947_19965	COG0631	protein serine/threonine phosphatase activity
OM947_19990	COG0667	Aldo Keto reductase
OM947_19995	COG0583	DNA-binding transcription factor activity
OM947_20070	COG0154	amidase activity
OM947_20075	COG3039	Transposase
OM947_20100	COG3328	transposase activity
OM947_20180	COG0210	DNA helicase
OM947_20195	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OM947_20200	COG0583	DNA-binding transcription factor activity
OM947_20205	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
OM947_20215	COG2159	amidohydrolase
OM947_20240	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OM947_20260	COG0357	Ribosomal RNA small subunit methyltransferase G
OM947_20265	COG3540	Alkaline phosphatase
OM947_20275	COG2091	lysine biosynthetic process via aminoadipic acid
OM947_20290	COG0708	Exodeoxyribonuclease III
OM947_20295	COG1940	carbohydrate kinase activity
OM947_20295	COG1846	Transcriptional regulator
OM947_20305	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
OM947_20315	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OM947_20320	COG3162	membrane
OM947_20330	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OM947_20365	COG3507	Belongs to the glycosyl hydrolase 43 family
OM947_20385	COG1028	Short-chain dehydrogenase reductase Sdr
OM947_20390	COG0179	Fumarylacetoacetate (FAA) hydrolase
OM947_20395	COG4948	Mandelate Racemase Muconate Lactonizing
OM947_20400	COG3254	rhamnose metabolic process
OM947_20405	COG0738	Major facilitator superfamily
OM947_20410	COG1414	Transcriptional regulator
OM947_20415	COG2207	Transcriptional regulator
OM947_20415	COG1917	Cupin 2, conserved barrel domain protein
OM947_20425	COG1971	Probably functions as a manganese efflux pump
OM947_20430	COG2205	protein histidine kinase activity
OM947_20440	COG3459	Glycosyltransferase 36 associated
OM947_20445	COG2211	Major facilitator Superfamily
OM947_20450	COG3265	gluconokinase activity
OM947_20455	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
OM947_20475	COG2911	Protein conserved in bacteria
OM947_20480	COG0729	surface antigen
OM947_20485	COG4771	TonB-dependent receptor
OM947_20490	COG0457	Tetratricopeptide repeat
OM947_20500	COG0752	glycyl-tRNA synthetase alpha subunit
OM947_20505	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
OM947_20515	COG0518	GMP synthase (glutamine-hydrolyzing) activity
OM947_20515	COG0519	Catalyzes the synthesis of GMP from XMP
OM947_20530	COG0805	protein transport
OM947_20535	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
OM947_20540	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
OM947_20550	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
OM947_20570	COG2974	May be involved in recombination
OM947_20575	COG0037	tRNA processing
OM947_20580	COG2115	Belongs to the xylose isomerase family
OM947_20590	COG3661	Belongs to the glycosyl hydrolase 67 family
OM947_20600	COG4948	Mandelate Racemase Muconate Lactonizing
OM947_20610	COG1472	Belongs to the glycosyl hydrolase 3 family
OM947_20615	COG0246	Mannitol dehydrogenase
OM947_20670	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
OM947_20695	COG3386	PFAM SMP-30 Gluconolaconase
OM947_20705	COG3250	beta-galactosidase activity
OM947_20710	COG1904	glucuronate isomerase
OM947_20715	COG3693	PFAM glycoside hydrolase, family 10
OM947_20730	COG3693	PFAM glycoside hydrolase, family 10
OM947_20745	COG2211	Major facilitator Superfamily
OM947_20795	COG3328	transposase activity
OM947_20840	COG2937	Belongs to the GPAT DAPAT family
OM947_20870	COG0284	orotidine-5'-phosphate decarboxylase activity
OM947_20875	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
OM947_20890	COG0635	Involved in the biosynthesis of porphyrin-containing compound
OM947_20940	COG0210	DNA helicase
OM947_20945	COG1435	thymidine kinase activity
OM947_20955	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
OM947_20965	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
OM947_20995	COG3135	benzoate transporter
OM947_21020	COG0676	glucose-6-phosphate 1-epimerase activity
OM947_21030	COG3012	SEC-C Motif Domain Protein
OM947_21080	COG3039	Transposase
OM947_21130	COG0730	response to heat
OM947_21140	COG3328	transposase activity
OM947_21160	COG0302	gtp cyclohydrolase
OM947_21175	COG1566	PFAM secretion protein HlyD family protein
OM947_21185	COG1289	transmembrane transporter activity
OM947_21190	COG0477	Major facilitator Superfamily
OM947_21200	COG0583	DNA-binding transcription factor activity
OM947_21205	COG4221	oxidoreductase activity
OM947_21215	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OM947_21240	COG3328	transposase activity
OM947_21265	COG0564	pseudouridine synthase activity
OM947_21295	COG3012	SEC-C Motif Domain Protein
OM947_21365	COG4790	Type iii secretion
OM947_21530	COG3039	Transposase
OM947_21565	COG2801	Transposase and inactivated derivatives
OM947_21625	COG0439	Biotin carboxylase
OM947_21650	COG1028	Short-chain dehydrogenase reductase Sdr
OM947_21700	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
OM947_21705	COG1074	ATP-dependent DNA helicase activity
OM947_21710	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
OM947_21745	COG1127	ABC transporter
OM947_21750	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
OM947_21755	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
OM947_21770	COG2853	Lipoprotein
OM947_21785	COG0386	Belongs to the glutathione peroxidase family
OM947_21795	COG1322	Protein conserved in bacteria
OM947_21805	COG0583	DNA-binding transcription factor activity
OM947_21825	COG0531	amino acid
OM947_21830	COG3537	Alpha-1,2-mannosidase
OM947_21850	COG2199	diguanylate cyclase activity
OM947_21850	COG2203	Gaf domain
OM947_21855	COG3835	regulator
OM947_21860	COG1929	Belongs to the glycerate kinase type-1 family
OM947_21880	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
OM947_21885	COG0861	Integral membrane protein TerC family
OM947_21895	COG0584	glycerophosphoryl diester phosphodiesterase
OM947_21910	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
OM947_21915	COG0726	polysaccharide deacetylase
OM947_21925	COG0706	membrane insertase activity
OM947_21930	COG0594	ribonuclease P activity
OM947_21945	COG3318	Belongs to the UPF0149 family
OM947_21945	COG3012	SEC-C Motif Domain Protein
OM947_21970	COG3328	transposase activity
OM947_22005	COG1196	nuclear chromosome segregation
OM947_22070	COG3328	transposase activity
OM947_22095	COG1192	Involved in chromosome partitioning
OM947_22200	COG3039	Transposase
OM947_22265	COG2801	Transposase and inactivated derivatives
OM947_22320	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
OM947_22340	COG1487	ribonuclease activity
OM947_22345	COG4691	Plasmid stability protein
OM947_22350	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
OM947_22400	COG3328	transposase activity
OM947_22485	COG1487	ribonuclease activity
OM947_22490	COG4691	Plasmid stability protein
OM947_22495	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
OM947_22600	COG4962	Type ii secretion system protein e
OM947_22615	COG3451	type IV secretory pathway VirB4
OM947_22620	COG3451	type IV secretory pathway VirB4
OM947_22635	COG3846	protein secretion by the type IV secretion system
OM947_22670	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OM947_22670	COG0551	DNA topoisomerase type I activity
OM947_22685	COG2951	lytic endotransglycosylase activity