locus-tag	class	description
AC609_00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
AC609_00015	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
AC609_00020	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AC609_00030	ENOG4108K0D	peptidase, M48
AC609_00080	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
AC609_00090	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
AC609_00115	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
AC609_00135	ENOG4105CN1	protease
AC609_00140	ENOG41063SB	peptidase
AC609_00150	ENOG4107VAM	peptidase, m28
AC609_00180	ENOG4105DQ4	alcohol dehydrogenase
AC609_00190	ENOG4105BZ8	glutamate synthase
AC609_00195	ENOG4105CBC	glutamate synthase
AC609_00220	ENOG4105EXG	Transcriptional regulator
AC609_00280	ENOG4108I5C	dEAD DEAH box helicase
AC609_00285	ENOG4108UT2	hemolysin iii
AC609_00295	ENOG4107FW0	short-chain dehydrogenase reductase
AC609_00300	ENOG4105CHR	reductase
AC609_00330	ENOG4105DYS	nad(p)h dehydrogenase (quinone)
AC609_00340	ENOG4105F2I	Transposase
AC609_00350	ENOG4105F2I	Transposase
AC609_00365	ENOG41067RQ	csbd family
AC609_00390	ENOG4105D4Y	metalloprotease
AC609_00415	ENOG4105K63	Thioredoxin
AC609_00420	ENOG4105CSH	Transporter
AC609_00460	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
AC609_00500	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AC609_00505	ENOG4105CGF	Aromatic amino acid aminotransferase
AC609_00510	ENOG4105CHB	tonB-dependent Receptor
AC609_00535	ENOG4105DMF	Dehydrogenase
AC609_00545	ENOG4105BZU	Histidine kinase
AC609_00550	ENOG4105WH1	Two component transcriptional regulator luxr family
AC609_00575	ENOG4105RKW	reductase (By
AC609_00580	ENOG4105F2I	Transposase
AC609_00600	ENOG4105EP6	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity)
AC609_00605	ENOG4105CG3	alpha amylase, catalytic region
AC609_00610	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
AC609_00625	ENOG4105EBR	Carboxylesterase
AC609_00640	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
AC609_00650	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
AC609_00655	ENOG4105DSG	hydrolase family 43
AC609_00660	ENOG4105ETE	Transcriptional regulator (LacI family
AC609_00665	ENOG4105D50	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate (By similarity)
AC609_00670	ENOG4105CHR	reductase
AC609_00680	ENOG4107TDE	lipolytic protein G-D-S-L family
AC609_00690	ENOG4105MIR	Phenylalanine 4-monooxygenase
AC609_00695	ENOG4108YXU	transcriptional regulator AsnC family
AC609_00700	ENOG4105CNM	Receptor
AC609_00705	ENOG4105D78	K07001 NTE family protein
AC609_00715	ENOG4105DKW	ABC transporter
AC609_00730	ENOG4108IJ8	ABC transporter
AC609_00735	ENOG4105E90	ABC transporter
AC609_00775	ENOG4105D1F	ATP-binding protein
AC609_00780	ENOG4105M4E	phosphohistidine phosphatase, SixA
AC609_00790	ENOG4107RZC	phospholipase d
AC609_00795	ENOG4105KA0	thioesterase Superfamily protein
AC609_00830	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
AC609_00835	ENOG4105C5F	glutamine synthetase
AC609_00845	ENOG4105BZU	Histidine kinase
AC609_00850	ENOG4105CUX	Signal transduction histidine kinase
AC609_00855	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AC609_00860	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
AC609_00865	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
AC609_00880	ENOG4105CHU	acetyl-coa acetyltransferase
AC609_00915	ENOG4107YZP	Rhodanese domain protein
AC609_00920	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
AC609_00925	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
AC609_00955	ENOG4108TQ9	Histidine kinase
AC609_00960	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AC609_00980	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
AC609_00995	ENOG4105E2T	synthase III
AC609_01000	ENOG4107R3N	Filamentation induced by cAMP protein fic
AC609_01005	ENOG4108J2P	Alpha beta hydrolase fold
AC609_01010	ENOG4105PI0	Ferredoxin
AC609_01015	ENOG410680H	amp-dependent synthetase and ligase
AC609_01020	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
AC609_01040	ENOG4105CPF	Cell wall formation (By similarity)
AC609_01050	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
AC609_01060	ENOG4105DR9	pseudouridine synthase
AC609_01070	ENOG4108YZN	class I peptide chain release factor
AC609_01080	ENOG4105D44	asparaginase
AC609_01085	ENOG4105DGW	oligopeptidase A
AC609_01125	ENOG4107QP3	malate synthase g
AC609_01135	ENOG4105BZU	Histidine kinase
AC609_01150	ENOG4105F2I	Transposase
AC609_01170	ENOG4107QX3	carboxylase
AC609_01175	ENOG4105C1G	acyl-Coa dehydrogenase
AC609_01245	ENOG4108TZV	Membrane
AC609_01255	ENOG4105D6Z	AFG1 family ATPase
AC609_01260	ENOG4105K56	Transcriptional regulator
AC609_01265	ENOG4108ZHJ	Organic hydroperoxide resistance protein
AC609_01285	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
AC609_01300	ENOG4108R99	pseudouridine synthase
AC609_01310	ENOG4105CQ7	ATP-dependent helicase
AC609_01315	ENOG4108W15	Protein of unknown function (DUF1456)
AC609_01320	ENOG4105VT2	5-hydroxyisourate hydrolase
AC609_01325	ENOG4105E1J	oxidoreductase
AC609_01345	ENOG4105C5R	Aminotransferase
AC609_01355	ENOG4105HEI	LysR family (Transcriptional regulator
AC609_01370	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
AC609_01380	ENOG4105DU0	nucleoside hydrolase
AC609_01390	ENOG4105C7N	Xanthine uracil vitamin C permease
AC609_01410	ENOG4105ETT	transcriptional Regulator, LysR family
AC609_01415	ENOG4105F8V	Hydrolase, tatD family
AC609_01430	ENOG4106NZI	LysR family Transcriptional regulator
AC609_01435	ENOG4105D94	Major Facilitator Superfamily
AC609_01450	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
AC609_01455	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
AC609_01475	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
AC609_01480	ENOG4105EB3	Histidine kinase
AC609_01485	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
AC609_01490	ENOG4105BZS	acriflavin resistance protein
AC609_01495	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
AC609_01510	ENOG4105WPN	DNA integration recombination invertion protein
AC609_01515	ENOG4105DZ2	Transcriptional regulator
AC609_01520	ENOG4108UZX	fmn reductase
AC609_01530	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
AC609_01535	ENOG4105CAX	The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity)
AC609_01555	ENOG4105ECR	NmrA family
AC609_01580	ENOG4105D5G	Transposase
AC609_01620	ENOG4105CMM	transposase
AC609_01630	ENOG4105C01	Dihydroxy-acid dehydratase
AC609_01650	ENOG4108Z0R	Transferase
AC609_01660	ENOG4105D2S	major facilitator superfamily
AC609_01665	ENOG4105CPI	Metal Dependent Phosphohydrolase
AC609_01695	ENOG41072AC	4-hydroxybenzoate 3-monooxygenase
AC609_01705	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
AC609_01710	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
AC609_01715	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
AC609_01720	ENOG4105E98	transcriptional regulator DeoR family
AC609_01745	ENOG4105CHU	acetyl-coa acetyltransferase
AC609_01760	ENOG4107RAW	3-carboxy-cis-cis-muconate cycloisomerase
AC609_01765	ENOG4105F2Z	3-oxoadipate enol-lactonase
AC609_01770	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
AC609_01780	ENOG4107HP6	Transcriptional regulator
AC609_01800	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
AC609_01840	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
AC609_01850	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
AC609_01855	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
AC609_01860	ENOG41081UC	Inherit from COG: Competence protein
AC609_01865	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
AC609_01885	ENOG4105F2I	Transposase
AC609_01925	ENOG4105VS8	Flagellar biosynthetic protein fliq
AC609_01945	ENOG4108HR8	type iii secretion
AC609_01965	ENOG4107Y59	type iii secretion
AC609_01980	ENOG4108JIR	Flagellum-specific ATP synthase
AC609_01990	ENOG4108TN6	type iii secretion
AC609_01995	ENOG4105K44	type iii secretion
AC609_02005	ENOG4105FTC	Lytic transglycosylase catalytic
AC609_02020	ENOG4105EGS	Mechanosensitive ion channel
AC609_02025	ENOG4107RES	phosphoglycerol transferase I
AC609_02035	ENOG4105CKW	Inner membrane protein yedI
AC609_02040	ENOG4105BZU	Histidine kinase
AC609_02045	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
AC609_02050	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
AC609_02055	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
AC609_02080	ENOG4105K4T	epimerase
AC609_02105	ENOG4105D5G	Transposase
AC609_02115	ENOG4105F2I	Transposase
AC609_02155	ENOG4105BZS	acriflavin resistance protein
AC609_02160	ENOG4105CHR	reductase
AC609_02170	ENOG4105C1J	atp-dependent rna helicase
AC609_02175	ENOG4105C7S	Dehydrogenase
AC609_02185	ENOG4105CPP	Dehydrogenase, E1 component
AC609_02190	ENOG4107RUY	(E1 component), alpha subunit
AC609_02200	ENOG4105HJ8	Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity)
AC609_02205	ENOG4105DUX	Transporter
AC609_02225	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
AC609_02230	ENOG4105F1J	Homogentisate 1,2-dioxygenase
AC609_02245	ENOG4105KJM	monovalent cation h antiporter subunit g
AC609_02250	ENOG4105W4C	monovalent cation H antiporter subunit F
AC609_02260	ENOG4107R4Z	monovalent cation h antiporter subunit d
AC609_02265	ENOG4108ZE9	Monovalent cation H antiporter subunit C
AC609_02270	ENOG4105D65	subunit l
AC609_02290	ENOG4105NVB	glycoside hydrolase, family 19
AC609_02310	ENOG4105C8V	SAICAR synthetase
AC609_02315	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
AC609_02335	ENOG4107TE5	Lipid kinase
AC609_02340	ENOG4105CRQ	synthase (Component I)
AC609_02350	ENOG4105DDQ	anthranilate synthase
AC609_02360	ENOG4108I0Q	anthranilate phosphoribosyltransferase
AC609_02365	ENOG4105DK0	Indole-3-glycerol phosphate synthase
AC609_02375	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
AC609_02380	ENOG4105FDS	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
AC609_02390	ENOG4108S0N	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol (By similarity)
AC609_02395	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
AC609_02400	ENOG4108UJD	30S ribosomal protein S9
AC609_02415	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
AC609_02425	ENOG4108UQY	Iron-storage protein
AC609_02430	ENOG4105BZU	Histidine kinase
AC609_02455	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
AC609_02470	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
AC609_02485	ENOG4108J8Q	Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity)
AC609_02500	ENOG4105EM2	membrane
AC609_02510	ENOG4105C12	Phosphoribosylglycinamide synthetase
AC609_02520	ENOG4105DC1	bifunctional purine biosynthesis protein purh
AC609_02525	ENOG4108UMZ	Cdp-alcohol phosphatidyltransferase
AC609_02530	ENOG4105E8V	Alpha Beta Hydrolase Fold protein
AC609_02535	ENOG41077RS	Phosphatase
AC609_02560	ENOG4108HPI	phosphatidate Cytidylyltransferase
AC609_02565	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
AC609_02590	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
AC609_02605	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
AC609_02615	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
AC609_02620	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
AC609_02630	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
AC609_02635	ENOG4105VF7	tolerance protein
AC609_02645	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
AC609_02665	ENOG4105EUP	HipA domain protein
AC609_02670	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
AC609_02700	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
AC609_02705	ENOG4105EX9	Membrane
AC609_02720	ENOG4105F2I	Transposase
AC609_02735	ENOG4108RDT	NADH dehydrogenase NAD(P)H nitroreductase)
AC609_02740	ENOG4108YYC	ycei family
AC609_02775	ENOG4105WSE	Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism (By similarity)
AC609_02790	ENOG41065ZS	Transfers 2'-(5-triphosphoribosyl)-3'-dephosphocoenzyme- A to the apo- acyl-carrier-protein of the malonate decarboxylase to yield holo- acyl-carrier-protein (By similarity)
AC609_02795	ENOG4108K6F	triphosphoribosyl-dephospho-CoA synthase
AC609_02800	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
AC609_02810	ENOG4105DRR	Transcriptional regulator, GntR family
AC609_02855	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
AC609_02860	ENOG4105D5G	Transposase
AC609_02870	ENOG4107GJV	short-chain dehydrogenase reductase
AC609_02895	ENOG4105PDP	Short chain dehydrogenase
AC609_02905	ENOG4105CHF	Glutathione S-transferase
AC609_02950	ENOG4107QS8	(LipO)protein
AC609_02955	ENOG4105BZU	Histidine kinase
AC609_02960	ENOG4108Z40	Transcriptional regulator
AC609_02985	ENOG4105DFI	Membrane
AC609_02990	ENOG4108YQE	rare lipoprotein a
AC609_03000	ENOG41065HY	1,4-beta-cellobiosidase
AC609_03015	ENOG4105C85	amino acid
AC609_03025	ENOG4105D7N	magnesium and cobalt transport protein CorA
AC609_03035	ENOG4105E53	ec 3.2.1.28
AC609_03075	ENOG4105BZU	Histidine kinase
AC609_03090	ENOG4106R7G	Glycoside hydrolase family 5
AC609_03120	ENOG4105C3A	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity)
AC609_03130	ENOG4108HRK	Histidine kinase
AC609_03135	ENOG4108NEV	two component transcriptional regulator, LytTR family
AC609_03140	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
AC609_03195	ENOG4105WD1	Membrane
AC609_03205	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
AC609_03215	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
AC609_03220	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
AC609_03225	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
AC609_03250	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
AC609_03255	ENOG4105BZU	Histidine kinase
AC609_03260	ENOG4105CD8	aminopeptidase N
AC609_03280	ENOG4105DZG	Dehydrogenase
AC609_03285	ENOG4108Q1J	Extracellular solute-binding protein, family 3
AC609_03310	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
AC609_03330	ENOG4105DFF	Rod shape-determining protein mreb
AC609_03335	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
AC609_03350	ENOG4105CNI	cell division protein FtsW
AC609_03360	ENOG4105F2I	Transposase
AC609_03380	ENOG4107WN4	Polygalacturonase
AC609_03385	ENOG4105CVE	Lytic murein transglycosylase
AC609_03390	ENOG4105K6T	rare lipoprotein A
AC609_03395	ENOG4105DZ1	carboxypeptidase
AC609_03410	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
AC609_03415	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
AC609_03420	ENOG4105CN1	protease
AC609_03430	ENOG4108KSA	LysR family transcriptional regulator
AC609_03475	ENOG4108J5G	6-phosphogluconate dehydrogenase
AC609_03480	ENOG4105D9R	oxidoreductase
AC609_03485	ENOG4105W4M	Transport-associated protein
AC609_03490	ENOG4105BZU	Histidine kinase
AC609_03500	ENOG4105BZU	Histidine kinase
AC609_03550	ENOG4105GVR	general secretion pathway protein D
AC609_03555	ENOG4107QHF	type ii secretion system protein e
AC609_03560	ENOG4105D7Q	type ii secretion system
AC609_03565	ENOG4108VAU	general secretion pathway protein G
AC609_03570	ENOG4105VWV	general secretion pathway protein h
AC609_03575	ENOG4105X5Z	General secretion pathway protein I
AC609_03585	ENOG4108RTD	type II secretion system protein K
AC609_03605	ENOG4105FDP	GntR family transcriptional regulator
AC609_03615	ENOG4105ETE	Transcriptional regulator (LacI family
AC609_03620	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
AC609_03625	ENOG4105CE4	GlcNAc 6-P deacetylase
AC609_03635	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
AC609_03640	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
AC609_03650	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
AC609_03665	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
AC609_03675	ENOG4108K5H	permease YjgP YjgQ family protein
AC609_03690	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
AC609_03695	ENOG4105T95	Thiol disulfide interChange protein
AC609_03700	ENOG4108ETH	Formylglycinamide ribotide synthetase
AC609_03710	ENOG4105EUR	Domain-Containing protein
AC609_03715	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
AC609_03720	ENOG4105EUR	Domain-Containing protein
AC609_03725	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
AC609_03730	ENOG4107QHF	type ii secretion system protein e
AC609_03735	ENOG4105D7Q	type ii secretion system
AC609_03745	ENOG4105WMT	general secretion pathway protein h
AC609_03755	ENOG41069G9	General secretion pathway protein J
AC609_03760	ENOG4105UV2	general secretion pathway protein K
AC609_03765	ENOG41090VX	general secretion pathway protein L
AC609_03770	ENOG410678M	general secretion pathway protein M
AC609_03780	ENOG4105GVR	general secretion pathway protein D
AC609_03790	ENOG4106S9K	Transcriptional regulator
AC609_03850	ENOG4107RH7	Nicotinate phosphoribosyltransferase
AC609_03865	ENOG4107QZ7	Cellulose synthase catalytic subunit
AC609_03870	ENOG4107EEX	Cellulose synthase regulator protein
AC609_03875	ENOG4105K2Z	endo-1,4-d-glucanase (EC 3.2.1.4)
AC609_03905	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
AC609_03910	ENOG4105C5H	ABC transporter
AC609_03920	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
AC609_03925	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
AC609_03935	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
AC609_03945	ENOG4105D5G	Transposase
AC609_03960	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
AC609_03965	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
AC609_03970	ENOG4107YIM	Involved in the transcription termination process (By similarity)
AC609_03975	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
AC609_03990	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
AC609_03995	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
AC609_04005	ENOG4105C08	Histidine kinase
AC609_04010	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
AC609_04020	ENOG4105CQB	FAD linked oxidase domain protein
AC609_04025	ENOG4105S2T	inner membrane protein YbcI
AC609_04030	ENOG41082RQ	UPF0102 protein
AC609_04055	ENOG4108V6E	Cell division protein mraZ
AC609_04065	ENOG4106932	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
AC609_04070	ENOG4105CJN	penicillin-binding protein
AC609_04075	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
AC609_04080	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
AC609_04085	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
AC609_04095	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
AC609_04100	ENOG4105DFU	Cell wall formation (By similarity)
AC609_04105	ENOG4105CPF	Cell wall formation (By similarity)
AC609_04110	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
AC609_04115	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
AC609_04120	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
AC609_04125	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
AC609_04135	ENOG4105DR5	peptidase
AC609_04140	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
AC609_04145	ENOG4105M6F	mutator MutT protein
AC609_04155	ENOG4105SYT	Methylenetetrahydrofolate reductase
AC609_04220	ENOG4105DXX	methyltransferase
AC609_04225	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
AC609_04235	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
AC609_04255	ENOG4105UYK	outer membrane protein a
AC609_04270	ENOG4105D6F	Phosphatase
AC609_04275	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
AC609_04285	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
AC609_04290	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
AC609_04300	ENOG4108RVA	ribokinase
AC609_04305	ENOG4105D9N	nucleoside
AC609_04310	ENOG4105CPC	Aldo Keto reductase
AC609_04320	ENOG4105D05	Receptor
AC609_04340	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
AC609_04355	ENOG4105E2B	Taurine dioxygenase
AC609_04365	ENOG4108I0Y	(ABC) transporter
AC609_04370	ENOG4108UJV	acyl-CoA thioesterase i
AC609_04375	ENOG4105ETX	regulatoR
AC609_04380	ENOG4105DHQ	Histidine kinase
AC609_04390	ENOG41080IJ	Diacylglycerol kinase
AC609_04400	ENOG4105HA9	of methanol dehydrogenase type
AC609_04410	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
AC609_04415	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
AC609_04430	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
AC609_04435	ENOG4105NWN	ApaG protein
AC609_04445	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
AC609_04450	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
AC609_04455	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
AC609_04470	ENOG4108WBT	adenosyltransferase
AC609_04480	ENOG4105D0A	hydroxylase
AC609_04485	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
AC609_04520	ENOG4105DDW	LysR family Transcriptional regulator
AC609_04525	ENOG4105CEY	Amp-dependent synthetase and ligase
AC609_04535	ENOG4108D7R	p-hydroxycinnamoyl CoA hydratase lyase
AC609_04565	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
AC609_04590	ENOG4105DXC	membrane
AC609_04600	ENOG4105CX6	glutaminyL-tRNA synthetase
AC609_04615	ENOG4105BZU	Histidine kinase
AC609_04620	ENOG4105BZU	Histidine kinase
AC609_04625	ENOG4105WH1	Two component transcriptional regulator luxr family
AC609_04645	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
AC609_04650	ENOG4105NXH	GreA GreB family elongation factor
AC609_04655	ENOG4105C5Q	Transcriptional regulator
AC609_04670	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
AC609_04690	ENOG4105C2M	dna polymerase I
AC609_04745	ENOG4105CM2	brancheD-chain amino acid aminotransferase
AC609_04750	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
AC609_04755	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
AC609_04760	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
AC609_04765	ENOG4108Z66	YbaK ebsC protein
AC609_04785	ENOG4105CS1	NAD(P)H quinone oxidoreductase
AC609_04790	ENOG4107S2Z	UPF0761 membrane protein
AC609_04795	ENOG4107QX9	Thiol disulfide interChange protein
AC609_04810	ENOG4105CSR	polyphosphate kinase 2
AC609_04815	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
AC609_04825	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
AC609_04830	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
AC609_04835	ENOG4105DJQ	tetratricopeptide tpr_2 repeat protein
AC609_04840	ENOG4105QVB	outer membrane lipoprotein LolB
AC609_04845	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
AC609_04855	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
AC609_04860	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
AC609_04865	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
AC609_04870	ENOG4105C3G	gtp-binding protein
AC609_04890	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
AC609_04900	ENOG4105PM1	preprotein translocase subunit SecE
AC609_04905	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
AC609_04910	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
AC609_04915	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
AC609_04920	ENOG4108VZM	50s ribosomal protein L10
AC609_04925	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
AC609_04930	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AC609_04935	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AC609_04940	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
AC609_04945	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
AC609_04950	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
AC609_04955	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
AC609_04965	ENOG4105D5G	Transposase
AC609_04970	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
AC609_04975	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
AC609_04980	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
AC609_04985	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
AC609_04990	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AC609_04995	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
AC609_05000	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
AC609_05005	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
AC609_05010	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
AC609_05020	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
AC609_05025	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
AC609_05030	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
AC609_05035	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AC609_05040	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
AC609_05045	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
AC609_05050	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
AC609_05055	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
AC609_05060	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
AC609_05070	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
AC609_05075	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
AC609_05080	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AC609_05085	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
AC609_05090	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
AC609_05095	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AC609_05100	ENOG4108ZT0	50S ribosomal protein l17
AC609_05105	ENOG41080I0	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
AC609_05125	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
AC609_05135	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
AC609_05150	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
AC609_05155	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
AC609_05160	ENOG4108K3A	Glutathione S-transferase
AC609_05170	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
AC609_05175	ENOG4105CIS	alcohol dehydrogenase
AC609_05180	ENOG4105D5G	Transposase
AC609_05185	ENOG4105F2I	Transposase
AC609_05190	ENOG4105F37	PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6
AC609_05200	ENOG4108R99	pseudouridine synthase
AC609_05210	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
AC609_05215	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
AC609_05220	ENOG4108I5D	sulfate abc transporter
AC609_05230	ENOG4108IJ6	ABC transporter
AC609_05240	ENOG4105D5G	Transposase
AC609_05245	ENOG4105CPQ	Dehydrogenase
AC609_05255	ENOG4105HSS	phospholipase C
AC609_05265	ENOG4105CVJ	phosphoglycerate mutase
AC609_05275	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
AC609_05290	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
AC609_05295	ENOG4105ED9	Protein of unknown function (DUF455)
AC609_05310	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
AC609_05315	ENOG4105EYK	Phosphatidylglycerophosphatase B
AC609_05320	ENOG4105BZF	Glycosyl transferase (Group 1
AC609_05325	ENOG4105C9X	ppx gppa phosphatase
AC609_05330	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
AC609_05335	ENOG4105BZU	Histidine kinase
AC609_05340	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AC609_05345	ENOG4105ERG	peptidase m48, ste24p
AC609_05350	ENOG4105VW4	glutaredoxin 3
AC609_05360	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
AC609_05395	ENOG4105D5G	Transposase
AC609_05410	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
AC609_05415	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
AC609_05420	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
AC609_05450	ENOG4105EIN	peptidylprolyl cis-trans isomerase
AC609_05460	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
AC609_05470	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
AC609_05475	ENOG4107RZZ	dna polymerase iii epsilon subunit
AC609_05480	ENOG4108ZF3	Phosphatase
AC609_05495	ENOG4105DKP	glycosyl transferase, family 9
AC609_05500	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
AC609_05505	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
AC609_05510	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
AC609_05520	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
AC609_05525	ENOG4105M00	molybdopterin converting factor, subunit 1
AC609_05530	ENOG4108ZAF	Molybdopterin
AC609_05540	ENOG4107QMP	dna polymerase iii subunits gamma and tau
AC609_05545	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
AC609_05550	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
AC609_05555	ENOG4105K59	histidine triad (HIT) protein
AC609_05565	ENOG4105F8C	transglutaminase domain-containing protein
AC609_05575	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
AC609_05585	ENOG4108UHJ	MAF-like protein
AC609_05590	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
AC609_05595	ENOG4105VGS	50s ribosomal protein l32
AC609_05600	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
AC609_05610	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
AC609_05615	ENOG4105CHR	reductase
AC609_05620	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
AC609_05625	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
AC609_05635	ENOG4105HHA	aminodeoxychorismate lyase
AC609_05640	ENOG4107QRG	dna polymerase iii
AC609_05670	ENOG4108JU7	Transcriptional regulator
AC609_05675	ENOG4105CR4	methylisocitrate lyase
AC609_05680	ENOG4105BZN	citrate synthase
AC609_05685	ENOG4108I0Z	Aconitate hydratase
AC609_05695	ENOG4105C7F	AcnD-accessory protein PrpF
AC609_05710	ENOG4105DN3	alpha-2-macroglobulin domain protein
AC609_05730	ENOG4105CUX	Signal transduction histidine kinase
AC609_05735	ENOG4108JQB	penicillin-binding protein 1C
AC609_05760	ENOG4105M3Z	response regulator
AC609_05765	ENOG4107QJR	hflk protein
AC609_05770	ENOG4105EPW	hflc protein
AC609_05780	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
AC609_05785	ENOG4105CD8	aminopeptidase N
AC609_05795	ENOG4105F6U	Short-chain dehydrogenase reductase Sdr
AC609_05800	ENOG4108XFH	Transcriptional regulator
AC609_05850	ENOG4107Z4K	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
AC609_05860	ENOG4105BZP	glycoside hydrolase 15-related
AC609_05865	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
AC609_05870	ENOG4105CWX	Alpha-1,2-mannosidase
AC609_05895	ENOG4105C3M	thioredoxin reductase
AC609_05930	ENOG4105C7W	Xanthine dehydrogenase
AC609_05935	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
AC609_05940	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
AC609_05975	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
AC609_05995	ENOG4105C0B	DNA polymerase III (alpha subunit)
AC609_06010	ENOG4105EPD	Oligopeptide transporter, Opt family
AC609_06035	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
AC609_06055	ENOG4106AXJ	AraC family transcriptional regulator
AC609_06070	ENOG4105D5G	Transposase
AC609_06085	ENOG4105CV8	reductase
AC609_06090	ENOG4105EBR	Carboxylesterase
AC609_06095	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AC609_06115	ENOG4108JJA	ABC, transporter
AC609_06120	ENOG4105C2C	drug resistance transporter, Bcr CflA
AC609_06160	ENOG4105DIJ	Phosphoethanolamine transferase
AC609_06175	ENOG4105ETX	regulatoR
AC609_06180	ENOG4105DHQ	Histidine kinase
AC609_06190	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
AC609_06195	ENOG4107QMS	site-determining protein
AC609_06200	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
AC609_06210	ENOG4105BZU	Histidine kinase
AC609_06215	ENOG4105WH1	Two component transcriptional regulator luxr family
AC609_06260	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
AC609_06270	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
AC609_06285	ENOG4105GFR	rna polymerase sigma factor
AC609_06295	ENOG4105C29	acyl-CoA thioesterase
AC609_06310	ENOG4108TGP	Thioesterase superfamily protein
AC609_06315	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
AC609_06320	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
AC609_06325	ENOG4105K46	50S ribosomal protein l27
AC609_06330	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AC609_06335	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
AC609_06340	ENOG4105CJR	Integral membrane protein (MviN
AC609_06345	ENOG4105DTN	riboflavin biosynthesis protein ribF
AC609_06350	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
AC609_06355	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
AC609_06360	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
AC609_06500	ENOG4105E2S	oxidase) subunit II
AC609_06505	ENOG4105BZ9	Cytochrome C oxidase, subunit I
AC609_06510	ENOG4105CCU	oxidase (Subunit III)
AC609_06515	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
AC609_06525	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
AC609_06530	ENOG4105KAF	membrAne
AC609_06545	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
AC609_06555	ENOG4107MMM	Anti-sigma-factor antagonist
AC609_06560	ENOG4105FUA	antagonist
AC609_06575	ENOG4105BZU	Histidine kinase
AC609_06600	ENOG4105KCV	RNA signal recognition particle 4.5S RNA
AC609_06605	ENOG4105C08	Histidine kinase
AC609_06610	ENOG4107Z5C	methylesterase
AC609_06615	ENOG4105BZU	Histidine kinase
AC609_06620	ENOG4105BZU	Histidine kinase
AC609_06635	ENOG4105CZZ	Alpha-N-arabinofuranosidase (EC 3.2.1.55)
AC609_06645	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
AC609_06655	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AC609_06665	ENOG4107QWG	2-Nitropropane dioxygenase
AC609_06670	ENOG4105CM2	brancheD-chain amino acid aminotransferase
AC609_06675	ENOG4105K5M	30s ribosomal protein S16
AC609_06680	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
AC609_06685	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
AC609_06690	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
AC609_06695	ENOG4107QJQ	Mate efflux family protein
AC609_06715	ENOG4105VEJ	Heat shock protein
AC609_06720	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
AC609_06730	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
AC609_06750	ENOG4105CMM	transposase
AC609_06755	ENOG4105CMM	transposase
AC609_06780	ENOG4105CNT	hydrolase family 2
AC609_06785	ENOG4106FKC	arabinogalactan endo-1,4-beta-galactosidase
AC609_06800	ENOG4105C26	Dehydrogenase
AC609_06805	ENOG4105C1G	acyl-Coa dehydrogenase
AC609_06815	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
AC609_06820	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
AC609_06835	ENOG4107RDJ	Sulfotransferase
AC609_06845	ENOG4107RDJ	Sulfotransferase
AC609_06855	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
AC609_06860	ENOG4105EMN	RNA polymerase sigma factor
AC609_06870	ENOG4105C0H	protease
AC609_06875	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
AC609_06880	ENOG4105C3F	Signal peptidase i
AC609_06890	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
AC609_06895	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
AC609_06900	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
AC609_06910	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
AC609_06915	ENOG41080ZE	Adenylate cyclase
AC609_06920	ENOG4107ZXU	DSBA oxidoreductase
AC609_06925	ENOG4108QDE	fad dependent oxidoreductase
AC609_06930	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
AC609_06935	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
AC609_06940	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
AC609_06945	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
AC609_06950	ENOG4105VEQ	Cold shock protein
AC609_06955	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
AC609_06965	ENOG4107QRT	dEAD DEAH box helicase
AC609_06970	ENOG4107T0X	DNA ligase
AC609_06980	ENOG4107T0X	DNA ligase
AC609_06995	ENOG4105BZU	Histidine kinase
AC609_07010	ENOG4105CHU	acetyl-coa acetyltransferase
AC609_07030	ENOG4108VKG	metal-dependent hydrolase
AC609_07045	ENOG4105KSC	Transcriptional regulator, TraR DksA family
AC609_07070	ENOG4108YZY	peptidylprolyl cis-trans isomerase
AC609_07080	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
AC609_07090	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
AC609_07095	ENOG4105F27	Major Facilitator
AC609_07140	ENOG4105M4H	endoribonuclease L-psp
AC609_07145	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
AC609_07160	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
AC609_07185	ENOG4105K6V	RNA polymerase
AC609_07205	ENOG4108R3D	Electron transport complex
AC609_07215	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
AC609_07235	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
AC609_07250	ENOG4108IQI	permease
AC609_07255	ENOG4107QK5	Homocysteine s-methyltransferase
AC609_07305	ENOG4108YXA	Membrane
AC609_07320	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
AC609_07335	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
AC609_07340	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
AC609_07345	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
AC609_07350	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
AC609_07365	ENOG4105DZP	Membrane-associated zinc metalloprotease
AC609_07370	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
AC609_07375	ENOG4105KNE	Phosphatidate cytidylyltransferase
AC609_07380	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
AC609_07385	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
AC609_07390	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
AC609_07395	ENOG4105BZU	Histidine kinase
AC609_07400	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
AC609_07405	ENOG4105CE9	30S ribosomal protein S2
AC609_07440	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
AC609_07445	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
AC609_07455	ENOG4105KUZ	arsenate reductase
AC609_07460	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
AC609_07465	ENOG4105CAQ	asparagine synthetase
AC609_07480	ENOG4108ESX	Receptor
AC609_07490	ENOG4108UWD	Iron-storage protein
AC609_07510	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AC609_07535	ENOG4105D5G	Transposase
AC609_07570	ENOG4105CW7	secretion protein, HlyD family
AC609_07575	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
AC609_07605	ENOG4105DUX	Transporter
AC609_07635	ENOG4105DGW	oligopeptidase A
AC609_07640	ENOG4108V06	Glutathione peroxidase
AC609_07645	ENOG4105DP0	ferredoxin-NADP reductase
AC609_07655	ENOG4107GFK	fumarate
AC609_07675	ENOG4105HDD	phospholipase
AC609_07685	ENOG4105VEQ	Cold shock protein
AC609_07700	ENOG4105CUZ	uba thif-type nad fad binding protein
AC609_07705	ENOG4105EYA	deoxyribonuclease
AC609_07720	ENOG4105C1G	acyl-Coa dehydrogenase
AC609_07730	ENOG4108RXX	maleylacetoacetate isomerase
AC609_07735	ENOG4105CAQ	asparagine synthetase
AC609_07745	ENOG4105CDU	Replicative dna helicase
AC609_07750	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
AC609_07755	ENOG4105CDV	Ompa motb domain protein
AC609_07760	ENOG4105CR8	Transcriptional regulator
AC609_07795	ENOG4105BZU	Histidine kinase
AC609_07805	ENOG4106TD9	Diguanylate cyclase
AC609_07825	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
AC609_07830	ENOG4108Z1B	Cyclase dehydrase
AC609_07840	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
AC609_07845	ENOG41090R7	Ferric uptake
AC609_07850	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
AC609_07855	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
AC609_07860	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AC609_07865	ENOG4105CFG	Acts as a chaperone (By similarity)
AC609_07870	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
AC609_07905	ENOG4105C5Q	Transcriptional regulator
AC609_07910	ENOG4105BZ1	(ABC) transporter
AC609_07920	ENOG4108URH	decarboxylase
AC609_07930	ENOG4105C7S	Dehydrogenase
AC609_07935	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
AC609_07945	ENOG4105EZE	Cupin 4 family protein
AC609_07955	ENOG4107QTF	adenylosuccinate lyase
AC609_07965	ENOG4105C37	(CBS) domain
AC609_07995	ENOG4105CZV	ABC transporter
AC609_08000	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
AC609_08010	ENOG4108V1T	peptidylprolyl cis-trans isomerase
AC609_08015	ENOG41069P5	Protein slyX homolog
AC609_08030	ENOG4105ETE	Transcriptional regulator (LacI family
AC609_08040	ENOG4105D7K	pfkb domain protein
AC609_08050	ENOG4105C3R	Methionine synthase
AC609_08055	ENOG4105C3R	Methionine synthase
AC609_08065	ENOG4105C1G	acyl-Coa dehydrogenase
AC609_08080	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
AC609_08090	ENOG4105C2N	RNA methyltransferase TrmH family group 3
AC609_08105	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
AC609_08115	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
AC609_08120	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
AC609_08125	ENOG4105E2Z	phosphate ABC transporter (Permease
AC609_08130	ENOG4105C8U	phosphate abc transporter
AC609_08135	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
AC609_08155	ENOG4107B2H	carbonic anhydrase
AC609_08160	ENOG4105CHH	sulfate transporter
AC609_08165	ENOG4105CSM	endonuclease III
AC609_08175	ENOG4105E39	Enoyl-CoA hydratase
AC609_08180	ENOG4108V1T	peptidylprolyl cis-trans isomerase
AC609_08185	ENOG4105P8F	nudix hydrolase
AC609_08190	ENOG4105KHC	sulfurtransferase
AC609_08220	ENOG4105C5H	ABC transporter
AC609_08230	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
AC609_08235	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
AC609_08255	ENOG4105CJB	Exodeoxyribonuclease I
AC609_08260	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
AC609_08265	ENOG4105CKY	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively (By similarity)
AC609_08275	ENOG4105C3W	Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate (By similarity)
AC609_08280	ENOG41077A9	carbonic anhydrase
AC609_08325	ENOG4105WH1	Two component transcriptional regulator luxr family
AC609_08355	ENOG4105C5S	asparaginyl-tRNA synthetase
AC609_08360	ENOG4108Z4V	iron-sulfur cluster assembly
AC609_08365	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
AC609_08370	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
AC609_08375	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
AC609_08385	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
AC609_08395	ENOG4105CIH	Imidazole acetol-phosphate transaminase
AC609_08400	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
AC609_08405	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
AC609_08415	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
AC609_08420	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AC609_08425	ENOG4105DZG	Dehydrogenase
AC609_08435	ENOG4105CGP	Urocanate hydratase
AC609_08450	ENOG4105C84	Histidine ammonia-lyase
AC609_08455	ENOG4105CI2	imidazolone-5-propionate hydrolase
AC609_08495	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
AC609_08500	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
AC609_08505	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
AC609_08515	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
AC609_08530	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
AC609_08535	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
AC609_08540	ENOG4105CC0	LysR family Transcriptional regulator
AC609_08605	ENOG4105CQZ	Histidine kinase
AC609_08630	ENOG4105KWW	Biogenesis protein
AC609_08635	ENOG4107QX9	Thiol disulfide interChange protein
AC609_08640	ENOG4105DA4	cytochrome c-type biogenesis protein
AC609_08645	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
AC609_08655	ENOG41060IM	Heme exporter protein
AC609_08670	ENOG4105EMN	RNA polymerase sigma factor
AC609_08720	ENOG4105EGZ	biosynthesis protein
AC609_08750	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
AC609_08775	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
AC609_08785	ENOG41079KZ	Major Facilitator Superfamily
AC609_08790	ENOG4105DEN	Luciferase family
AC609_08815	ENOG4105CJ3	phosphate transporter
AC609_08830	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AC609_08840	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
AC609_08845	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
AC609_08855	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
AC609_08860	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
AC609_08870	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
AC609_08875	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
AC609_08880	ENOG4108DG9	Smr protein MutS2
AC609_08885	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
AC609_08890	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
AC609_08895	ENOG4108UM1	dedA family
AC609_08900	ENOG4108K5P	(LipO)protein
AC609_08905	ENOG4108UIV	Protein of unknown function (DUF498/DUF598)
AC609_08910	ENOG4105HBR	Rna-binding protein
AC609_08915	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
AC609_08920	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
AC609_08925	ENOG4105EEI	dihydropteroate synthase
AC609_08930	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
AC609_08935	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
AC609_08940	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
AC609_08945	ENOG4107TH8	cina domain protein
AC609_08950	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
AC609_08955	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
AC609_08960	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
AC609_08965	ENOG4105Y3E	Modulates RecA activity (By similarity)
AC609_08970	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
AC609_08975	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
AC609_08985	ENOG4107SDU	Methyl-accepting chemotaxis
AC609_09000	ENOG4105CWB	LysR family transcriptional Regulator
AC609_09040	ENOG4108IAB	Phoh family
AC609_09045	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AC609_09060	ENOG4107TUS	Dihydrodipicolinate synthase
AC609_09070	ENOG4108Z4U	Ferredoxin
AC609_09075	ENOG4105EI3	2-dehydro-3-deoxygalactonokinase EC 2.7.1.58
AC609_09085	ENOG4105CXK	mandelate racemase muconate lactonizing
AC609_09090	ENOG4108RTU	Aldolase
AC609_09140	ENOG4105CMG	Carbohydrate kinase
AC609_09145	ENOG4105C93	Xylose Isomerase
AC609_09160	ENOG4105D5G	Transposase
AC609_09175	ENOG4108KNB	n-acetylmuramoyl-l-alanine amidase
AC609_09180	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
AC609_09195	ENOG4105DJ0	Poly(A) Polymerase
AC609_09200	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AC609_09205	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
AC609_09210	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
AC609_09215	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
AC609_09220	ENOG4107QP8	phosphohexose isomerase
AC609_09260	ENOG4105KU2	hydrolase family 5
AC609_09265	ENOG4108UYB	regulatoR
AC609_09275	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
AC609_09280	ENOG410841Q	phosphoesterase PA-phosphatase related protein
AC609_09285	ENOG4105CSH	Transporter
AC609_09295	ENOG4108SXK	Transporter Drug Metabolite Exporter family
AC609_09300	ENOG4105D4A	Cell wall formation (By similarity)
AC609_09305	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
AC609_09320	ENOG4105C26	Dehydrogenase
AC609_09335	ENOG4105D5G	Transposase
AC609_09340	ENOG4105D5G	Transposase
AC609_09345	ENOG4105CG3	alpha amylase, catalytic region
AC609_09380	ENOG4105ETE	Transcriptional regulator (LacI family
AC609_09385	ENOG4105C22	threonyL-tRNA synthetase
AC609_09390	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
AC609_09395	ENOG41082NX	50s ribosomal protein l35
AC609_09400	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
AC609_09405	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
AC609_09410	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
AC609_09415	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
AC609_09420	ENOG4105WJX	transcriptional regulator MERR family
AC609_09440	ENOG4105D3Q	Sugar transferase
AC609_09465	ENOG4107Y2G	Glycosyl transferase (Group 1
AC609_09475	ENOG4108NQK	Catalyzes the transfer of a glucuronic acid (GlcA) residue from UDP-glucuronate to mannose-alpha-1,3-glucose-beta- 1,4-glucose-P-P-polyisoprenyl to form the lipid-linked tetrasaccharide GlcA-Man-Glc(2)-PP-Pol, with a glucuronic acid- beta-mannose linkage. Is involved in the biosynthesis of the exopolysaccharide xanthan, since it catalyzes the fourth glycosylation step in the assembly of the pentasaccharide-P-P- polyisoprenyl repeating unit of xanthan. Is unable to use the trisaccharide acceptor freed from the pyrophosphate lipid moiety. Does not show specificity for the lipidic portion of the acceptor. Shows diminished activity when tested with 6-O-acetyl-mannose- alpha-1,3-glucose-beta-1,4-glucose-P-P-polyisoprenyl, a
AC609_09500	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
AC609_09510	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
AC609_09530	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
AC609_09540	ENOG4105CSU	acyl-Coa dehydrogenase
AC609_09550	ENOG4105QNF	Outer membrane lipoprotein
AC609_09565	ENOG4105DKD	Incises the DNA at the 3' side of a lesion during nucleotide excision repair. Incises the DNA farther away from the lesion than UvrC. Not able to incise the 5' site of a lesion. When a lesion remains because UvrC is not able to induce the 3' incision, Cho incises the DNA. Then UvrC makes the 5' incision. The combined action of Cho and UvrC broadens the substrate range of nucleotide excision repair (By similarity)
AC609_09580	ENOG4105CQZ	Histidine kinase
AC609_09600	ENOG4105CEN	a g-specific adenine glycosylase
AC609_09605	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
AC609_09615	ENOG4105CTU	Proline racemase
AC609_09620	ENOG41080HI	glycine oxidase
AC609_09635	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
AC609_09645	ENOG4105DC7	peptidase M24
AC609_09660	ENOG4107QTZ	amino acid
AC609_09775	ENOG4105D5G	Transposase
AC609_09820	ENOG4105D5G	Transposase
AC609_09830	ENOG4105CMM	transposase
AC609_09840	ENOG4105KAV	tspo and mbr like protein
AC609_09845	ENOG4105D5G	Transposase
AC609_09850	ENOG4105CFH	Aspartokinase
AC609_09865	ENOG4105R0I	Feruloyl esterase
AC609_09885	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
AC609_09890	ENOG4105CUT	histidyl-tRNA synthetase
AC609_09905	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
AC609_09910	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
AC609_09915	ENOG4105CIH	Imidazole acetol-phosphate transaminase
AC609_09920	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
AC609_09925	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
AC609_09930	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
AC609_09935	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
AC609_09940	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
AC609_09955	ENOG4106YVY	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) (By similarity)
AC609_09960	ENOG4108CAF	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity)
AC609_09965	ENOG4107QY0	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity)
AC609_09970	ENOG4105CUB	amino acid
AC609_09975	ENOG4105CUB	amino acid
AC609_09985	ENOG4108JQ1	Dehydrogenase
AC609_09990	ENOG4105CQB	FAD linked oxidase domain protein
AC609_10010	ENOG4105FUQ	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
AC609_10020	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
AC609_10040	ENOG4105CE1	Ferrous iron transport protein b
AC609_10055	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
AC609_10060	ENOG4108RPX	mosc domain containing protein
AC609_10065	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
AC609_10070	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
AC609_10080	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
AC609_10085	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
AC609_10095	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
AC609_10110	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
AC609_10115	ENOG4105CRK	lysyL-tRNA synthetase
AC609_10120	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
AC609_10125	ENOG4105BZU	Histidine kinase
AC609_10130	ENOG4105BZU	Histidine kinase
AC609_10135	ENOG4105E39	Enoyl-CoA hydratase
AC609_10140	ENOG4105CEY	Amp-dependent synthetase and ligase
AC609_10155	ENOG4107QM5	aconitate hydratase
AC609_10170	ENOG4107QIJ	Aconitate hydratase 2
AC609_10175	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
AC609_10180	ENOG4105BZU	Histidine kinase
AC609_10185	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
AC609_10190	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
AC609_10195	ENOG4105BZU	Histidine kinase
AC609_10200	ENOG4105C8Q	Methyl-accepting chemotaxis
AC609_10210	ENOG4108V3W	Chemotaxis protein, CheW
AC609_10220	ENOG4105C8Q	Methyl-accepting chemotaxis
AC609_10225	ENOG4105C8Q	Methyl-accepting chemotaxis
AC609_10230	ENOG4105C8Q	Methyl-accepting chemotaxis
AC609_10235	ENOG4105C8Q	Methyl-accepting chemotaxis
AC609_10240	ENOG4105C8Q	Methyl-accepting chemotaxis
AC609_10250	ENOG4105C8Q	Methyl-accepting chemotaxis
AC609_10255	ENOG4105C8Q	Methyl-accepting chemotaxis
AC609_10265	ENOG4105C8Q	Methyl-accepting chemotaxis
AC609_10275	ENOG4105C8Q	Methyl-accepting chemotaxis
AC609_10280	ENOG4105C8Q	Methyl-accepting chemotaxis
AC609_10290	ENOG4105C8Q	Methyl-accepting chemotaxis
AC609_10295	ENOG4105C8Q	Methyl-accepting chemotaxis
AC609_10300	ENOG4105CBS	Chea signal transduction histidine kinase
AC609_10305	ENOG4108VYJ	response regulator receiver protein
AC609_10315	ENOG4108V3W	Chemotaxis protein, CheW
AC609_10320	ENOG4107QJE	Chromosome Partitioning Protein
AC609_10325	ENOG4105ER2	Ompa motb domain protein
AC609_10330	ENOG4105E14	MotA TolQ exbB proton channel
AC609_10370	ENOG4105CBS	Chea signal transduction histidine kinase
AC609_10380	ENOG4108VYJ	response regulator receiver protein
AC609_10385	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AC609_10390	ENOG4107R21	site-determining protein
AC609_10395	ENOG4105FZW	flagellar biosynthesis regulator FlhF
AC609_10400	ENOG4105D7B	Flagellar biosynthesis protein flha
AC609_10405	ENOG4105D00	flagellar biosynthetic protein flhB
AC609_10410	ENOG4105BZU	Histidine kinase
AC609_10420	ENOG4105F2I	Transposase
AC609_10430	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
AC609_10435	ENOG4105VS8	Flagellar biosynthetic protein fliq
AC609_10440	ENOG4105F2I	Transposase
AC609_10445	ENOG4105CN7	Flagellar biosynthetic protein FliP
AC609_10450	ENOG4105K0P	flagellar biosynthesis protein
AC609_10455	ENOG4105DD5	Flagellar motor switch protein
AC609_10460	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
AC609_10480	ENOG4108JIR	Flagellum-specific ATP synthase
AC609_10490	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
AC609_10495	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
AC609_10500	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
AC609_10505	ENOG4107RGC	Glycosyl transferase, family 2
AC609_10525	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
AC609_10540	ENOG4105D5G	Transposase
AC609_10575	ENOG4108P1X	synthase
AC609_10590	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AC609_10595	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
AC609_10600	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AC609_10620	ENOG4105MQ3	flagellar protein FliS
AC609_10625	ENOG4107W9T	flagellar hook-associated
AC609_10635	ENOG4105F2I	Transposase
AC609_10640	ENOG4105DTJ	flagellar hook-associated protein
AC609_10650	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
AC609_10655	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
AC609_10660	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
AC609_10665	ENOG4105CGA	flagellar basal-body rod protein FlgG
AC609_10680	ENOG4108KPB	Flagellar basal-body rod protein FlgF
AC609_10685	ENOG4105BZE	flagellar hook protein, FlgE
AC609_10690	ENOG410822I	Flagellar hook capping protein
AC609_10695	ENOG4108ZC9	flagellar basal-body rod protein flgc
AC609_10705	ENOG4107R88	Chemotaxis protein (CheV)
AC609_10730	ENOG4105BZU	Histidine kinase
AC609_10735	ENOG4105BZU	Histidine kinase
AC609_10740	ENOG4105BZU	Histidine kinase
AC609_10745	ENOG4105BZU	Histidine kinase
AC609_10765	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
AC609_10775	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
AC609_10780	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
AC609_10785	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
AC609_10790	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
AC609_10800	ENOG4105C3M	thioredoxin reductase
AC609_10805	ENOG4105CNU	cell division protein FtsK
AC609_10815	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
AC609_10825	ENOG4105D1H	recombination factor protein RarA
AC609_10830	ENOG41082MI	Protein CrcB homolog
AC609_10835	ENOG4105CHU	acetyl-coa acetyltransferase
AC609_10850	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
AC609_10855	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
AC609_10865	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
AC609_10875	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
AC609_10880	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
AC609_10885	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
AC609_10890	ENOG4105D06	uba thif-type nad fad binding protein
AC609_10925	ENOG4105CGK	Exodeoxyribonuclease III
AC609_10935	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
AC609_10940	ENOG41085AN	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
AC609_10960	ENOG4105H3G	oxidoreductase
AC609_10965	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
AC609_10975	ENOG4105I5W	Transporter
AC609_10985	ENOG4108IFG	nitrite reductase, (NAD(P)H)
AC609_11000	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
AC609_11010	ENOG4108N8X	transition metal ion binding
AC609_11040	ENOG4108ZXC	Two component transcriptional regulator, luxr family
AC609_11090	ENOG4105D5G	Transposase
AC609_11100	ENOG4105F2I	Transposase
AC609_11105	ENOG4105D5G	Transposase
AC609_11115	ENOG4105D5G	Transposase
AC609_11125	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
AC609_11140	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
AC609_11160	ENOG4105D5G	Transposase
AC609_11235	ENOG4105D5G	Transposase
AC609_11245	ENOG4107SKI	cobyrinic Acid a,c-diamide synthase
AC609_11290	ENOG4106RHG	Yeca family
AC609_11330	ENOG4105D5G	Transposase
AC609_11360	ENOG4105MKU	Transcriptional regulator
AC609_11375	ENOG41090A4	Pterin carbinolamine dehydratase
AC609_11385	ENOG4105DUN	Mediates zinc uptake. May also transport other divalent cations (By similarity)
AC609_11390	ENOG4108NST	exported protein
AC609_11395	ENOG4105EI2	Pseudouridine synthase
AC609_11400	ENOG4105C03	ribonuclease
AC609_11405	ENOG4105F2I	Transposase
AC609_11415	ENOG4105C72	UPF0176 protein
AC609_11425	ENOG4108V1T	peptidylprolyl cis-trans isomerase
AC609_11435	ENOG4107QQG	Dehydrogenase
AC609_11460	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
AC609_11465	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
AC609_11480	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
AC609_11485	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
AC609_11490	ENOG4105BZ1	(ABC) transporter
AC609_11505	ENOG4108EC8	DNA internalization-related competence protein ComEC
AC609_11515	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
AC609_11520	ENOG4105D60	lipoprotein releasing system transmembrane protein
AC609_11530	ENOG410681N	tpr repeat protein
AC609_11555	ENOG410612Q	succinate dehydrogenase (cytochrome b-556 subunit)
AC609_11560	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
AC609_11575	ENOG4105CHC	glucokinase (EC 2.7.1.2)
AC609_11580	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
AC609_11585	ENOG4105C01	Dihydroxy-acid dehydratase
AC609_11590	ENOG4108UHU	Aldolase
AC609_11615	ENOG4105N7H	Cytochrome
AC609_11660	ENOG4105BZU	Histidine kinase
AC609_11665	ENOG4105BZM	domain protein
AC609_11690	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
AC609_11700	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
AC609_11720	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
AC609_11735	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
AC609_11740	ENOG4108Z6B	deaminase
AC609_11745	ENOG4105KST	dependent repressor
AC609_11750	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
AC609_11770	ENOG4107SFI	Major Facilitator superfamily
AC609_11785	ENOG4105CHJ	isochorismatase hydrolase
AC609_11805	ENOG4105WH1	Two component transcriptional regulator luxr family
AC609_11840	ENOG4105DND	Transcriptional regulator
AC609_11850	ENOG4105EVH	UPF0753 protein
AC609_11860	ENOG4105CB2	alcohol dehydrogenase
AC609_11865	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
AC609_11925	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
AC609_11930	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
AC609_11935	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
AC609_11945	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
AC609_11950	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
AC609_11960	ENOG4105ESV	Glycosyl transferase, family 4
AC609_11965	ENOG4105CFV	Tetratricopeptide repeat protein
AC609_11975	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
AC609_11980	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
AC609_11985	ENOG4105CAT	Cytidine monophosphate kinase
AC609_11990	ENOG4105YK5	50S ribosomal protein L36
AC609_12000	ENOG4105DWY	Agmatine deiminase
AC609_12030	ENOG4105DRS	transport system, permease
AC609_12035	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
AC609_12070	ENOG4105K9H	YciI-like protein
AC609_12075	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
AC609_12080	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
AC609_12085	ENOG4105FE9	pseudouridine synthase
AC609_12100	ENOG4105CZ7	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
AC609_12105	ENOG4105CHM	Aminotransferase
AC609_12110	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
AC609_12115	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
AC609_12120	ENOG41060IM	Heme exporter protein
AC609_12130	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
AC609_12135	ENOG4105DA4	cytochrome c-type biogenesis protein
AC609_12145	ENOG4105KWW	Biogenesis protein
AC609_12150	ENOG4108M1T	Cytochrome c-type biogenesis protein
AC609_12155	ENOG4105DWV	Homoserine O-trans-acetylase
AC609_12165	ENOG4108JJ8	(ABC) transporter
AC609_12170	ENOG4108JJ9	ABC, transporter
AC609_12175	ENOG4105C4M	(Ubiquinol oxidase) subunit I
AC609_12180	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
AC609_12210	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
AC609_12215	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
AC609_12225	ENOG4105CH7	arginosuccinase
AC609_12230	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
AC609_12240	ENOG4105CAS	nag kinase
AC609_12255	ENOG4105CDH	Citrulline--aspartate ligase
AC609_12260	ENOG4105DBV	ornithine carbamoyltransferase
AC609_12270	ENOG4105C8N	cysteinyl-tRNA synthetase
AC609_12275	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
AC609_12285	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AC609_12295	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
AC609_12300	ENOG4105CD3	dihydroorotase
AC609_12320	ENOG4105CPD	ethanolamine ammonia-lyase
AC609_12325	ENOG4107FQ9	ethanolamine ammonia-lyase
AC609_12350	ENOG4105F2I	Transposase
AC609_12375	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
AC609_12380	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
AC609_12385	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
AC609_12395	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
AC609_12400	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
AC609_12405	ENOG4105BZU	Histidine kinase
AC609_12420	ENOG4105ECY	inositol monophosphatase
AC609_12425	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
AC609_12440	ENOG4105C5H	ABC transporter
AC609_12445	ENOG4105C1J	atp-dependent rna helicase
AC609_12450	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
AC609_12455	ENOG4105CNG	UPF0061 protein
AC609_12475	ENOG4108RXX	maleylacetoacetate isomerase
AC609_12480	ENOG4105VEQ	Cold shock protein
AC609_12485	ENOG4108VWS	Yaeq family
AC609_12490	ENOG4105CBX	hi0933 family
AC609_12500	ENOG4105D0M	Protease HtpX homolog
AC609_12505	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
AC609_12510	ENOG4105CHR	reductase
AC609_12530	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
AC609_12535	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
AC609_12540	ENOG4105K8N	protein family UPF0079, ATPase
AC609_12545	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
AC609_12550	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
AC609_12555	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
AC609_12565	ENOG4105E6M	Sulphatase-modifying factor protein
AC609_12575	ENOG4105DQE	DNA ligase
AC609_12605	ENOG4108V3W	Chemotaxis protein, CheW
AC609_12610	ENOG4105C8Q	Methyl-accepting chemotaxis
AC609_12615	ENOG4108VX5	3-methyladenine DNA glycosylase
AC609_12620	ENOG4107QRT	dEAD DEAH box helicase
AC609_12635	ENOG4105KB2	stringent starvation protein b
AC609_12640	ENOG4107MKT	Stringent starvation protein a
AC609_12645	ENOG4105EIX	cytochrome c1
AC609_12650	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
AC609_12655	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
AC609_12665	ENOG4105E4C	Lytic transglycosylase catalytic
AC609_12680	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
AC609_12685	ENOG4105C9A	Phoh family
AC609_12695	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
AC609_12705	ENOG4108JU5	Magnesium and cobalt efflux protein
AC609_12730	ENOG4105D38	putrescine abc transporter
AC609_12735	ENOG4105F38	ABC transporter, permease
AC609_12740	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
AC609_12760	ENOG4107RUE	extracellular solute-binding protein family 1
AC609_12765	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
AC609_12780	ENOG4105CFQ	glutamine synthetase
AC609_12785	ENOG4105CJP	fad dependent oxidoreductase
AC609_12790	ENOG4105BZU	Histidine kinase
AC609_12795	ENOG4105W3S	hemerythrin-like, metal-binding protein
AC609_12800	ENOG4105CSH	Transporter
AC609_12810	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
AC609_12815	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
AC609_12820	ENOG4105FCD	Major Facilitator
AC609_12825	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
AC609_12835	ENOG4106BRA	Membrane
AC609_12840	ENOG4105BZU	Histidine kinase
AC609_12845	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
AC609_12850	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
AC609_12855	ENOG4105C8Q	Methyl-accepting chemotaxis
AC609_12885	ENOG4105C7I	Dehydrogenase
AC609_12895	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
AC609_12900	ENOG4105BZS	acriflavin resistance protein
AC609_12905	ENOG4108M60	Transcriptional regulator
AC609_12910	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
AC609_12915	ENOG4105DE4	1-phosphofructokinase
AC609_12920	ENOG4105DM4	PTS System
AC609_12935	ENOG4105D5G	Transposase
AC609_12940	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
AC609_12945	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
AC609_12950	ENOG4105VIE	preprotein translocase, subunit YajC
AC609_12955	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
AC609_12960	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
AC609_13005	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
AC609_13010	ENOG4105E08	Glycoside hydrolase, family 9
AC609_13020	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
AC609_13025	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
AC609_13040	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
AC609_13045	ENOG4106H78	methyltransferase
AC609_13050	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
AC609_13160	ENOG4105CMA	conjugation trbi family protein
AC609_13195	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
AC609_13265	ENOG4105CMM	transposase
AC609_13365	ENOG4105NVB	glycoside hydrolase, family 19
AC609_13410	ENOG4105ED4	portal protein
AC609_13440	ENOG4105CMM	transposase
AC609_13490	ENOG4108HRK	Histidine kinase
AC609_13495	ENOG4105EWT	decarboxylase family
AC609_13500	ENOG4108KPZ	tonB-dependent Receptor
AC609_13505	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
AC609_13515	ENOG4105M2J	Glutaredoxin
AC609_13520	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
AC609_13525	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
AC609_13530	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
AC609_13540	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
AC609_13550	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
AC609_13555	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
AC609_13560	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
AC609_13565	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
AC609_13575	ENOG4105CHV	Transcription elongation factor NusA
AC609_13580	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
AC609_13590	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AC609_13595	ENOG4105C8S	subunit m
AC609_13600	ENOG4105D65	subunit l
AC609_13610	ENOG4105DF2	NADH dehydrogenase subunit j
AC609_13615	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AC609_13620	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
AC609_13625	ENOG4107R0R	NADH dehydrogenase subunit g
AC609_13630	ENOG4107QIZ	NADH dehydrogenase
AC609_13635	ENOG4105GKE	subunit e
AC609_13640	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AC609_13645	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AC609_13650	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AC609_13655	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AC609_13670	ENOG4105CP7	Triose-phosphate isomerase
AC609_13675	ENOG4105EMU	Dehydrogenase
AC609_13690	ENOG4105BZU	Histidine kinase
AC609_13710	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
AC609_13715	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
AC609_13720	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
AC609_13730	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
AC609_13740	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
AC609_13745	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
AC609_13765	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
AC609_13770	ENOG4105C5I	Dehydrogenase
AC609_13775	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
AC609_13780	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
AC609_13790	ENOG4105DJ4	phosphatidylserine decarboxylase
AC609_13800	ENOG4105D7A	ATP-binding protein
AC609_13820	ENOG4108RRZ	Transcription elongation factor GreB
AC609_13825	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
AC609_13850	ENOG4105DHP	deoxycytidine triphosphate deaminase
AC609_13890	ENOG4105C9K	Endothelin-converting enzyme 1
AC609_13915	ENOG4105DC8	reductase
AC609_13920	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
AC609_13930	ENOG4108YZY	peptidylprolyl cis-trans isomerase
AC609_13935	ENOG4105K4H	Nlp p60 protein
AC609_13940	ENOG4105K4H	Nlp p60 protein
AC609_13950	ENOG41082K6	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
AC609_13960	ENOG4105G6Z	alkaline phosphatase
AC609_13965	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
AC609_13970	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
AC609_13975	ENOG4105CTB	Polyprenyl synthetase
AC609_13990	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
AC609_13995	ENOG4105N42	UPF0307 protein
AC609_14000	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
AC609_14010	ENOG4105QD6	exported protein
AC609_14015	ENOG4105C03	ribonuclease
AC609_14020	ENOG4108Z03	MAF-like protein
AC609_14025	ENOG4105MPN	Membrane
AC609_14040	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
AC609_14055	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
AC609_14070	ENOG4105C8T	Leucyl-tRNA synthetase
AC609_14080	ENOG4107QR8	Thioredoxin
AC609_14105	ENOG4105WG9	Conserved Protein
AC609_14110	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
AC609_14160	ENOG4105BZ1	(ABC) transporter
AC609_14185	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
AC609_14190	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AC609_14195	ENOG4105BZU	Histidine kinase
AC609_14205	ENOG4105FQP	Beta-lactamase
AC609_14210	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
AC609_14225	ENOG4105BZU	Histidine kinase
AC609_14230	ENOG4105FE9	pseudouridine synthase
AC609_14235	ENOG4105BZU	Histidine kinase
AC609_14245	ENOG4105EMN	RNA polymerase sigma factor
AC609_14280	ENOG4105D03	DNA-3-methyladenine glycosylase II
AC609_14315	ENOG4105UGU	tonB-dependent Receptor
AC609_14360	ENOG4105CPC	Aldo Keto reductase
AC609_14365	ENOG4105F27	Major Facilitator
AC609_14370	ENOG4105CC0	LysR family Transcriptional regulator
AC609_14380	ENOG4105CF7	AraC family transcriptional regulator
AC609_14390	ENOG4108JGH	Tetr family transcriptional regulator
AC609_14395	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
AC609_14400	ENOG4105BZS	acriflavin resistance protein
AC609_14405	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
AC609_14415	ENOG4105MYN	Zinc uptake regulation protein
AC609_14420	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
AC609_14445	ENOG4105CT7	inner membrane cred family protein
AC609_14465	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
AC609_14470	ENOG4105D6S	protein involved in catabolism of external DNA
AC609_14490	ENOG4108JA2	transcriptioN-repair coupling factor
AC609_14500	ENOG4105CBS	Chea signal transduction histidine kinase
AC609_14505	ENOG4105C8Q	Methyl-accepting chemotaxis
AC609_14510	ENOG4108V3W	Chemotaxis protein, CheW
AC609_14515	ENOG4105BZU	Histidine kinase
AC609_14520	ENOG4105BZU	Histidine kinase
AC609_14525	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
AC609_14535	ENOG4105C9K	Endothelin-converting enzyme 1
AC609_14550	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
AC609_14565	ENOG4105EUB	pirin domain protein
AC609_14580	ENOG4105EUB	pirin domain protein
AC609_14585	ENOG4105D22	carbon starvation protein
AC609_14590	ENOG4105VCD	cytoplasmic protein
AC609_14635	ENOG4107XAN	XdhC and CoxI family
AC609_14640	ENOG4105C7W	Xanthine dehydrogenase
AC609_14645	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
AC609_14650	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
AC609_14665	ENOG4108UUM	single-stranded DNA-binding protein
AC609_14670	ENOG4105EAH	synthase
AC609_14680	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
AC609_14695	ENOG4105CFH	Aspartokinase
AC609_14700	ENOG4105JAB	phenazine biosynthesis protein, phzf family
AC609_14705	ENOG4105JAB	phenazine biosynthesis protein, phzf family
AC609_14715	ENOG4108Z9K	Osmotically inducible protein
AC609_14720	ENOG4105CXT	aspartate transcarbamylase
AC609_14725	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
AC609_14730	ENOG4108UJU	UPF0301 protein
AC609_14735	ENOG4108MAJ	Membrane
AC609_14740	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
AC609_14755	ENOG4105CZX	twitching motility protein
AC609_14760	ENOG4105CZX	twitching motility protein
AC609_14765	ENOG4105DFA	alanine racemase domain protein
AC609_14770	ENOG4105II7	pyrroline-5-carboxylate reductase
AC609_14780	ENOG4105FAA	peptidase M23
AC609_14800	ENOG4108Z0Z	intracellular protease Pfpi family
AC609_14820	ENOG4105C3K	feS assembly ATPase SufC
AC609_14825	ENOG4105JRK	feS assembly protein SufD
AC609_14830	ENOG4105C9B	Cysteine desulfurase
AC609_14835	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
AC609_14845	ENOG4108IU3	tonb-dependent siderophore receptor
AC609_14850	ENOG4107E2E	PKHD-type hydroxylase
AC609_14875	ENOG4105D5G	Transposase
AC609_14880	ENOG4105CJ2	(LipO)protein
AC609_14885	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
AC609_14890	ENOG41090B9	response to stress
AC609_14895	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
AC609_14910	ENOG4105EHM	Aminoglycoside phosphotransferase
AC609_14915	ENOG4108S0S	Nucleotidyl transferase
AC609_14925	ENOG4105C02	permease
AC609_14935	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
AC609_14950	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
AC609_14970	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
AC609_14980	ENOG4105C2X	Arabinose 5-phosphate isomerase
AC609_14985	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
AC609_14995	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
AC609_15000	ENOG4108IUZ	ABC transporter
AC609_15005	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AC609_15010	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
AC609_15015	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
AC609_15020	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
AC609_15025	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
AC609_15035	ENOG41080Z8	PHOSPHOCARRIER protein
AC609_15050	ENOG4105CJW	magnesium transporter
AC609_15055	ENOG4107UWA	esterase
AC609_15060	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
AC609_15125	ENOG4105CVE	Lytic murein transglycosylase
AC609_15190	ENOG4105C4M	(Ubiquinol oxidase) subunit I
AC609_15200	ENOG4105C85	amino acid
AC609_15205	ENOG4108NFF	pectate lyase
AC609_15215	ENOG4105CMM	transposase
AC609_15240	ENOG4105CUB	amino acid
AC609_15295	ENOG4108Z4X	TRANSCRIPTIONal
AC609_15305	ENOG4106032	Glutathionylspermidine synthase
AC609_15330	ENOG4108P9J	Phage shock protein A
AC609_15340	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
AC609_15345	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
AC609_15350	ENOG4105D49	3-dehydroquinate synthase
AC609_15360	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
AC609_15365	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
AC609_15370	ENOG4105BZU	Histidine kinase
AC609_15375	ENOG4105BZU	Histidine kinase
AC609_15380	ENOG4105BZU	Histidine kinase
AC609_15390	ENOG4105BZU	Histidine kinase
AC609_15395	ENOG4108YYC	ycei family
AC609_15415	ENOG4105EJQ	L-serine dehydratase
AC609_15425	ENOG4105CFH	Aspartokinase
AC609_15430	ENOG4105C28	cystathionine
AC609_15435	ENOG4106TYC	homoserine o-acetyltransferase (EC 2.3.1.31)
AC609_15440	ENOG4105DR5	peptidase
AC609_15445	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
AC609_15450	ENOG4108UT2	hemolysin iii
AC609_15455	ENOG41066T0	asmA family
AC609_15460	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
AC609_15470	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
AC609_15475	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
AC609_15485	ENOG4105D05	Receptor
AC609_15490	ENOG4108IG5	Transcriptional regulator
AC609_15500	ENOG4107QPN	acyl-Coa dehydrogenase
AC609_15525	ENOG4105D5G	Transposase
AC609_15545	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
AC609_15550	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
AC609_15560	ENOG4107QX8	SPFH domain, Band 7 family protein
AC609_15565	ENOG4105KK4	UPF0060 membrane protein
AC609_15575	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
AC609_15580	ENOG4107RK2	ADP-ribose diphosphatase NudE
AC609_15590	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
AC609_15595	ENOG4105CHC	glucokinase (EC 2.7.1.2)
AC609_15625	ENOG4105VRS	hydrolase family 18
AC609_15630	ENOG4105E2D	ec 3.2.1.52
AC609_15650	ENOG4105CWX	Alpha-1,2-mannosidase
AC609_15685	ENOG4106N3A	copper homeostasis protein cutc
AC609_15700	ENOG4105D9U	N-acetyltransferase
AC609_15715	ENOG4105CBS	Chea signal transduction histidine kinase
AC609_15720	ENOG4105C8Q	Methyl-accepting chemotaxis
AC609_15730	ENOG4105M3Z	response regulator
AC609_15735	ENOG4108UNF	response regulator
AC609_15740	ENOG4105D7Z	glutathione synthase
AC609_15750	ENOG41065RQ	ADP-ribosylation crystallin J1
AC609_15755	ENOG41072GX	Peptidase M22 Glycoprotease
AC609_15765	ENOG4105DVT	helicase
AC609_15775	ENOG4105BZ4	penicillin-binding protein
AC609_15790	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
AC609_15795	ENOG4105JIE	May be involved in the transport of PQQ or its precursor to the periplasm (By similarity)
AC609_15800	ENOG41086XE	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ (By similarity)
AC609_15805	ENOG4105Z85	coenzyme PQQ synthesis
AC609_15810	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
AC609_15825	ENOG4105CHC	glucokinase (EC 2.7.1.2)
AC609_15835	ENOG4105D5G	Transposase
AC609_15845	ENOG4105CQ7	ATP-dependent helicase
AC609_15855	ENOG4105C9U	ATP-dependent DNA helicase RecQ
AC609_15910	ENOG4105C8Q	Methyl-accepting chemotaxis
AC609_15930	ENOG410903D	sensor protein
AC609_15945	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
AC609_15955	ENOG4105KCK	Peptidoglycan-associated lipoprotein
AC609_15960	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
AC609_15975	ENOG4105E02	MotA TolQ exbB proton channel
AC609_15980	ENOG4107YD3	Thioesterase
AC609_15985	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
AC609_15995	ENOG4105DFH	Transport of potassium into the cell (By similarity)
AC609_16000	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
AC609_16005	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
AC609_16010	ENOG4105CDY	transcriptional regulatory protein
AC609_16025	ENOG4105C9M	aspartyl-trna synthetase
AC609_16040	ENOG4108ISG	Major Facilitator
AC609_16050	ENOG4105HSS	phospholipase C
AC609_16070	ENOG4105ETT	transcriptional Regulator, LysR family
AC609_16080	ENOG4105C5H	ABC transporter
AC609_16085	ENOG4107RNH	Outer membrane receptor FepA
AC609_16095	ENOG4107RNH	Outer membrane receptor FepA
AC609_16100	ENOG4107RNH	Outer membrane receptor FepA
AC609_16110	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
AC609_16135	ENOG4105GAV	receptor
AC609_16160	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
AC609_16185	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
AC609_16190	ENOG4108YZT	Adenosylcobinamide kinase
AC609_16195	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
AC609_16200	ENOG4105EFT	decarboxylase
AC609_16205	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
AC609_16210	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
AC609_16225	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
AC609_16235	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
AC609_16280	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
AC609_16285	ENOG4108K4C	ec 3.1.3.12
AC609_16290	ENOG4105BZP	glycoside hydrolase 15-related
AC609_16295	ENOG4105C1K	alpha-alpha-trehalose-phosphate synthase
AC609_16300	ENOG4105DZG	Dehydrogenase
AC609_16320	ENOG4105C8Q	Methyl-accepting chemotaxis
AC609_16325	ENOG4105KIR	Thiol-disulfide oxidoreductase dcc
AC609_16340	ENOG4105C34	Pseudouridine synthase
AC609_16345	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AC609_16355	ENOG4105C4K	Nad synthetase
AC609_16370	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
AC609_16375	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
AC609_16380	ENOG4107TUY	Histidine kinase
AC609_16390	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AC609_16395	ENOG4107QHF	type ii secretion system protein e
AC609_16400	ENOG4107QHF	type ii secretion system protein e
AC609_16415	ENOG4105D5G	Transposase
AC609_16425	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
AC609_16430	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
AC609_16445	ENOG4105BZU	Histidine kinase
AC609_16450	ENOG4105ETX	regulatoR
AC609_16460	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
AC609_16500	ENOG4105W5Q	DNA repair protein (RadC
AC609_16520	ENOG4105F2I	Transposase
AC609_16525	ENOG4105D5G	Transposase
AC609_16535	ENOG4105D5G	Transposase
AC609_16540	ENOG4105ESI	atpase involved in dna repair
AC609_16565	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
AC609_16570	ENOG4105KT5	UmuD protein
AC609_16590	ENOG4107QJE	Chromosome Partitioning Protein
AC609_16655	ENOG4108IYH	Dna topoisomerase
AC609_16660	ENOG4105NI8	Cytosine-specific methyltransferase
AC609_16745	ENOG4105D5G	Transposase
AC609_16970	ENOG4106NZI	LysR family Transcriptional regulator
AC609_16990	ENOG4105DFP	Integrase
AC609_17010	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
AC609_17015	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
AC609_17045	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
AC609_17060	ENOG4105ETE	Transcriptional regulator (LacI family
AC609_17085	ENOG4105C2N	RNA methyltransferase TrmH family group 3
AC609_17095	ENOG4105CD8	aminopeptidase N
AC609_17100	ENOG4105BZS	acriflavin resistance protein
AC609_17110	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
AC609_17115	ENOG4105C11	sulfate adenylyltransferase), subunit 2
AC609_17120	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
AC609_17125	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
AC609_17130	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
AC609_17150	ENOG4105BZU	Histidine kinase
AC609_17160	ENOG4107R11	Transcriptional regulator
AC609_17180	ENOG4108UVJ	appr-1-p processing domain protein
AC609_17185	ENOG4107R1Y	fructose-bisphosphate aldolase
AC609_17190	ENOG4105CA9	Pyruvate kinase
AC609_17200	ENOG4105BZA	Phosphoglycerate kinase
AC609_17230	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
AC609_17240	ENOG4105EIF	outer membrane protein W
AC609_17255	ENOG4107S76	domain protein
AC609_17260	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
AC609_17265	ENOG4105E0C	molybdate abc transporter
AC609_17270	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
AC609_17290	ENOG4105DHQ	Histidine kinase
AC609_17295	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
AC609_17315	ENOG4108IQE	Amp-dependent synthetase and ligase
AC609_17340	ENOG4107Y2H	ErfK ybiS ycfS ynhG family protein
AC609_17345	ENOG4105DR5	peptidase
AC609_17365	ENOG4105CV1	Transketolase (EC 2.2.1.1)
AC609_17370	ENOG4105CK2	sodium dicarboxylate symporter
AC609_17380	ENOG4107QVM	von Willebrand factor, type A
AC609_17400	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
AC609_17405	ENOG4105E4G	Type IV pilus
AC609_17430	ENOG4108JQC	penicillin-binding protein 1A
AC609_17445	ENOG4105NRA	50s ribosomal protein l31 type b
AC609_17450	ENOG4105DU0	nucleoside hydrolase
AC609_17455	ENOG4105CB5	ATP-dependent DNA helicase recG
AC609_17460	ENOG4105KME	endoribonuclease L-psp
AC609_17465	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
AC609_17470	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
AC609_17475	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
AC609_17480	ENOG4105DSJ	YicC domain protein
AC609_17485	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
AC609_17495	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
AC609_17500	ENOG4105CSA	Coproporphyrinogen iii oxidase
AC609_17515	ENOG4105D9Y	Splits dipeptides with a prolyl residue in the C- terminal position (By similarity)
AC609_17525	ENOG4107RAQ	aminopeptidase
AC609_17530	ENOG4105E07	UPF0149 protein
AC609_17540	ENOG4105W8B	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
AC609_17545	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
AC609_17565	ENOG41063JG	Transcriptional regulator
AC609_17570	ENOG4105VCQ	rubredoxin
AC609_17575	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
AC609_17605	ENOG41061ZR	Transcriptional regulator
AC609_17610	ENOG41090JD	Blue (Type 1) copper domain protein
AC609_17615	ENOG4105CIH	Imidazole acetol-phosphate transaminase
AC609_17645	ENOG4105C8Y	Acetylornithine aminotransferase
AC609_17650	ENOG4105EYW	Ion transport protein
AC609_17665	ENOG410841Q	phosphoesterase PA-phosphatase related protein
AC609_17670	ENOG4105FFC	UPF0187 protein
AC609_17680	ENOG4105DFU	Cell wall formation (By similarity)
AC609_17685	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
AC609_17700	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
AC609_17710	ENOG4105F0N	pyrophosphate phospho-hydrolase
AC609_17725	ENOG4105ECQ	AraC Family Transcriptional Regulator
AC609_17730	ENOG4108M3R	transcriptional activator CadC
AC609_17735	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
AC609_17745	ENOG4105C8Q	Methyl-accepting chemotaxis
AC609_17750	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
AC609_17755	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
AC609_17770	ENOG4105C7B	Threonine dehydratase
AC609_17775	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
AC609_17780	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
AC609_17785	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
AC609_17790	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
AC609_17795	ENOG4108MP6	LysR family Transcriptional regulator
AC609_17810	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
AC609_17815	ENOG4105DFG	type I secretion outer membrane protein
AC609_17820	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
AC609_17825	ENOG4105D1S	lipid A biosynthesis
AC609_17850	ENOG4105C6K	Malic enzyme
AC609_17855	ENOG4105CK2	sodium dicarboxylate symporter
AC609_17865	ENOG4105CQZ	Histidine kinase
AC609_17870	ENOG4105CSH	Transporter
AC609_17880	ENOG4105F04	LysR family Transcriptional regulator
AC609_17890	ENOG4105CPC	Aldo Keto reductase
AC609_17905	ENOG4105WH1	Two component transcriptional regulator luxr family
AC609_17910	ENOG4106JDA	Phosphoglycerate transport regulatory protein PGTC
AC609_17915	ENOG4105DHQ	Histidine kinase
AC609_17930	ENOG4105D4T	Citrate transporter
AC609_17935	ENOG4105CHR	reductase
AC609_17940	ENOG4105ETE	Transcriptional regulator (LacI family
AC609_17955	ENOG4107QW3	Sucrose phosphorylase
AC609_17970	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
AC609_17975	ENOG4105CHM	Aminotransferase
AC609_18010	ENOG41069H0	dihydroorotase EC 3.5.2.3
AC609_18015	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
AC609_18040	ENOG4105D5G	Transposase
AC609_18050	ENOG4108RMV	DegV Family
AC609_18070	ENOG4105C4W	S-formylglutathione hydrolase
AC609_18075	ENOG4108QBQ	Catalyzes the condensation of formaldehyde and glutathione to S-hydroxymethylglutathione (By similarity)
AC609_18100	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
AC609_18105	ENOG4105JJR	Histidine kinase
AC609_18130	ENOG4106RE7	Cytochrome
AC609_18140	ENOG4108Z33	Thiol disulfide Interchange Protein
AC609_18150	ENOG4105C94	Transporter
AC609_18155	ENOG4105C26	Dehydrogenase
AC609_18160	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
AC609_18185	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
AC609_18195	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
AC609_18200	ENOG4105VFQ	Histone family protein nucleoid-structuring protein H-NS
AC609_18215	ENOG4105DHJ	ABC, transporter
AC609_18220	ENOG4108SNX	Mammalian cell entry related domain protein
AC609_18235	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
AC609_18250	ENOG4107QKV	phosphomannomutase
AC609_18255	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
AC609_18265	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
AC609_18270	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
AC609_18285	ENOG4105BZJ	Electron transfer flavoprotein
AC609_18290	ENOG4105C10	Electron transfer flavoprotein
AC609_18305	ENOG4105IQ5	FAD linked oxidase domain protein
AC609_18315	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
AC609_18350	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
AC609_18355	ENOG4105CGN	Glycosyl transferase (Group 1
AC609_18365	ENOG4105EY8	ABC transporter
AC609_18395	ENOG4105C28	cystathionine
AC609_18420	ENOG4105CZX	twitching motility protein
AC609_18425	ENOG4108RXX	maleylacetoacetate isomerase
AC609_18435	ENOG4105C1J	atp-dependent rna helicase
AC609_18440	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
AC609_18450	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
AC609_18470	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
AC609_18475	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
AC609_18480	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
AC609_18490	ENOG4106MWK	domain protein
AC609_18500	ENOG4105DGW	oligopeptidase A
AC609_18515	ENOG4105E3B	Multicopper oxidase
AC609_18550	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
AC609_18555	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
AC609_18560	ENOG4105C19	ABC transporter
AC609_18565	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AC609_18580	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AC609_18590	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
AC609_18605	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
AC609_18610	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
AC609_18615	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
AC609_18620	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
AC609_18625	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
AC609_18630	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
AC609_18635	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
AC609_18640	ENOG4107RAZ	it plays a direct role in the translocation of protons across the membrane (By similarity)
AC609_18660	ENOG4107QN2	dihydrolipoyl dehydrogenase
AC609_18670	ENOG4107QSN	dihydrolipoamide acetyltransferase
AC609_18705	ENOG4105D01	(LipO)protein
AC609_18710	ENOG4108UMI	ABC transporter, permease
AC609_18715	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
AC609_18720	ENOG4108EHX	EamA-like transporter family
AC609_18725	ENOG4108VPT	UPF0234 protein
AC609_18735	ENOG4105BZU	Histidine kinase
AC609_18755	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
AC609_18760	ENOG4107S75	HAD-superfamily hydrolase subfamily IA variant 3
AC609_18765	ENOG4105I08	Pseudouridine synthase
AC609_18770	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
AC609_18780	ENOG4105F2I	Transposase
AC609_18785	ENOG4105D5G	Transposase
AC609_18800	ENOG4105BZU	Histidine kinase
AC609_18820	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
AC609_18825	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
AC609_18830	ENOG4105EW9	transcriptional regulator AsnC family
AC609_18850	ENOG4107RD7	Flagellar Motor Protein, MotA
AC609_18855	ENOG4105ER2	Ompa motb domain protein
AC609_18880	ENOG4105E3A	(ABC) transporter
AC609_18885	ENOG4105DA5	(ABC) transporter
AC609_18890	ENOG4105EEQ	Na H antiporter
AC609_18900	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
AC609_18910	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
AC609_18920	ENOG4105CBN	LysR family transcriptional regulator
AC609_18930	ENOG4105CPC	Aldo Keto reductase
AC609_18940	ENOG4105C9K	Endothelin-converting enzyme 1
AC609_18955	ENOG4107QTZ	amino acid
AC609_18965	ENOG4108VAC	response regulator
AC609_18970	ENOG4105C2F	Histidine kinase
AC609_18985	ENOG4108Z9Z	response to DNA damage stimulus
AC609_18990	ENOG4105WEF	catalase
AC609_19010	ENOG4105BZU	Histidine kinase
AC609_19025	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AC609_19040	ENOG4105C4M	(Ubiquinol oxidase) subunit I
AC609_19045	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
AC609_19060	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
AC609_19080	ENOG4105E2A	Dehydrogenase
AC609_19090	ENOG4105D5G	Transposase
AC609_19140	ENOG4105CIG	ABC transporter
AC609_19155	ENOG4108UQ8	endoribonuclease L-psp
AC609_19185	ENOG4105CHH	sulfate transporter
AC609_19190	ENOG4105CMQ	Chloride channel
AC609_19235	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AC609_19240	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
AC609_19245	ENOG4105D1S	lipid A biosynthesis
AC609_19250	ENOG4108Z7F	N-acetyltransferase
AC609_19295	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
AC609_19300	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
AC609_19305	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
AC609_19310	ENOG4108WZM	domain protein
AC609_19315	ENOG4105C79	DNA protecting protein DprA
AC609_19320	ENOG4108RPN	Protein smg homolog
AC609_19335	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
AC609_19340	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
AC609_19355	ENOG4105CHR	reductase
AC609_19365	ENOG4105D07	Signal peptide peptidase, SppA
AC609_19370	ENOG4107QI1	Mate efflux family protein
AC609_19390	ENOG4105C25	Primosomal protein n'
AC609_19395	ENOG4108TGY	Glutathione S-transferase
AC609_19415	ENOG4105EN6	Membrane
AC609_19420	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AC609_19425	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
AC609_19430	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
AC609_19435	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
AC609_19440	ENOG4105CAK	Cell division ATP-binding protein ftsE
AC609_19445	ENOG4105C1J	atp-dependent rna helicase
AC609_19450	ENOG4105K63	Thioredoxin
AC609_19455	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
AC609_19465	ENOG4105VS7	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity)
AC609_19480	ENOG4105E9K	Isocitrate dehydrogenase
AC609_19490	ENOG4109066	lysm domain bon superfamily protein
AC609_19495	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
AC609_19500	ENOG4105CH2	amidohydrolase
AC609_19505	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
AC609_19510	ENOG4105BZS	acriflavin resistance protein
AC609_19530	ENOG4105E32	cytoplasmic protein
AC609_19555	ENOG4105D5G	Transposase
AC609_19575	ENOG4108UQS	dipeptidase
AC609_19580	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
AC609_19600	ENOG4105D5Q	Arginine ornithine antiporter
AC609_19620	ENOG4105D5G	Transposase
AC609_19645	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
AC609_19650	ENOG4107ZVW	dihydroneopterin aldolase
AC609_19655	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
AC609_19660	ENOG4105VCC	30S ribosomal protein S21
AC609_19665	ENOG4105KTH	gatB Yqey
AC609_19675	ENOG4107S2Z	UPF0761 membrane protein
AC609_19680	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
AC609_19685	ENOG4105DHU	Bile acid
AC609_19695	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
AC609_19720	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
AC609_19725	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
AC609_19740	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
AC609_19780	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
AC609_19785	ENOG4105DR5	peptidase
AC609_19790	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
AC609_19800	ENOG4105EYM	Major Facilitator superfamily
AC609_19805	ENOG4105CGK	Exodeoxyribonuclease III
AC609_19810	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
AC609_19820	ENOG4107QJE	Chromosome Partitioning Protein
AC609_19825	ENOG4105FA0	parb-like partition protein
AC609_19840	ENOG4105CKK	Glycosyl transferase, family 2
AC609_19860	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
AC609_19865	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
AC609_19870	ENOG4105W5Q	DNA repair protein (RadC
AC609_19875	ENOG4105C75	arginyL-tRNA synthetase
AC609_19890	ENOG4105EMU	Dehydrogenase
AC609_19900	ENOG4105EXC	Acyl-transferase
AC609_19910	ENOG4105CEY	Amp-dependent synthetase and ligase
AC609_19915	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
AC609_19920	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
AC609_19945	ENOG4105CPE	K01197 hyaluronoglucosaminidase EC 3.2.1.35
AC609_19950	ENOG4108YZA	Nitrogen regulatory protein pii
AC609_19955	ENOG4105W0Z	cytoplasmic protein
AC609_19960	ENOG4105C0P	Mg chelatase subunit ChlI
AC609_19975	ENOG41066DG	(EAL) domain protein
AC609_19990	ENOG4105EJ2	Transcriptional regulator
AC609_20010	ENOG4105E0Y	RtcB Protein
AC609_20050	ENOG4105ECP	epimerase
AC609_20055	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
AC609_20060	ENOG4105DHQ	Histidine kinase
AC609_20080	ENOG4105C0H	protease
AC609_20100	ENOG4105DSF	transport protein
AC609_20105	ENOG4105DFC	had-superfamily hydrolase, subfamily ia, variant
AC609_20110	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
AC609_20125	ENOG4107VGR	Catalase
AC609_20145	ENOG4108S01	response regulator
AC609_20150	ENOG4108ZGX	Histidine kinase
AC609_20155	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
AC609_20160	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AC609_20185	ENOG4105FDR	Membrane
AC609_20205	ENOG4108NNI	Beta-lactamase domain-containing protein
AC609_20210	ENOG4105C31	Tryptophanyl-tRNA synthetase
AC609_20215	ENOG4105VDW	Csbd family
AC609_20275	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
AC609_20285	ENOG4105EXZ	Involved in the regulation of ptsG expression by binding and inactivating Mlc (By similarity)
AC609_20300	ENOG4105EB3	Histidine kinase
AC609_20305	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
AC609_20315	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
AC609_20330	ENOG4105CH6	catalase
AC609_20355	ENOG4105D5G	Transposase
AC609_20365	ENOG4108MBX	Secretion Protein
AC609_20370	ENOG4105DVT	helicase
AC609_20385	ENOG4105E2X	shikimate dehydrogenase
AC609_20405	ENOG4105D52	delta-aminolevulinic acid dehydratase
AC609_20460	ENOG4105QV4	Tryptophan halogenase
AC609_20475	ENOG4108IUW	ABC transporter
AC609_20485	ENOG4105VZ8	Transcriptional regulator
AC609_20505	ENOG4105PGM	cation diffusion facilitator family transporter
AC609_20510	ENOG4108JA0	Oxidoreductase, FAD NAD(P)-binding domain protein
AC609_20515	ENOG4105DA5	(ABC) transporter
AC609_20520	ENOG4105E3A	(ABC) transporter
AC609_20525	ENOG41063V1	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
AC609_20555	ENOG4105K63	Thioredoxin
AC609_20575	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
AC609_20580	ENOG4107QYD	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
AC609_20590	ENOG4105CD5	CoA-binding domain protein
AC609_20595	ENOG4105CJW	magnesium transporter
AC609_20620	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
AC609_20625	ENOG4105BZP	glycoside hydrolase 15-related
AC609_20645	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
AC609_20655	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
AC609_20665	ENOG4105C2D	reductase
AC609_20705	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
AC609_20710	ENOG4105E9Q	Acyl-transferase
AC609_20720	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
AC609_20760	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
AC609_20765	ENOG4105C2M	dna polymerase I
AC609_20795	ENOG4107TPY	serine threonine protein kinase
AC609_20800	ENOG4108ZF3	Phosphatase
AC609_20825	ENOG4107S5I	aldo keto reductase
AC609_20830	ENOG410642W	LysR family Transcriptional regulator
AC609_20845	ENOG4105CS6	Rhs element vgr protein
AC609_20900	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
AC609_20930	ENOG4105D5G	Transposase
AC609_20935	ENOG4105F2I	Transposase
AC609_20980	ENOG4108WC9	type VI secretion system effector, hcp1 family
AC609_21015	ENOG4105C4R	Atp-dependent dna helicase
AC609_21030	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
AC609_21035	ENOG4108KB2	LysR family Transcriptional regulator
AC609_21040	ENOG4105JSC	dimethylmenaquinone methyltransferase
AC609_21050	ENOG4105KHM	amidohydrolase 2
AC609_21055	ENOG4105W0E	50S ribosomal protein L33
AC609_21060	ENOG4105KDC	50s ribosomal protein l28
AC609_21080	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
AC609_21100	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
AC609_21105	ENOG4105DGI	Alkaline phosphatase
AC609_21135	ENOG4105CGK	Exodeoxyribonuclease III
AC609_21140	ENOG4105E2R	ROK family
AC609_21160	ENOG4107QN1	sodium solute
AC609_21165	ENOG41062QD	Membrane
AC609_21175	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
AC609_21200	ENOG4105DSG	hydrolase family 43
AC609_21220	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
AC609_21225	ENOG4105ERH	Fumarylacetoacetate hydrolase
AC609_21230	ENOG4105DIA	mandelate racemase muconate lactonizing
AC609_21235	ENOG4105QJH	Domain of unknown function (DUF718)
AC609_21240	ENOG4105EDR	glucose galactose transporter
AC609_21245	ENOG4108K2P	TRANSCRIPTIONal
AC609_21250	ENOG4106HBX	Transcriptional Regulator AraC Family
AC609_21260	ENOG4108UI1	Probably functions as a manganese efflux pump (By similarity)
AC609_21265	ENOG4105BZU	Histidine kinase
AC609_21275	ENOG4105E2V	Glycosyltransferase 36
AC609_21280	ENOG4105CT4	transporter
AC609_21285	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
AC609_21310	ENOG4105MA0	exported protein
AC609_21315	ENOG4105CFU	surface antigen
AC609_21320	ENOG4105D05	Receptor
AC609_21330	ENOG4107RDJ	Sulfotransferase
AC609_21340	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
AC609_21345	ENOG4107QHF	type ii secretion system protein e
AC609_21355	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
AC609_21370	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
AC609_21375	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
AC609_21390	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
AC609_21420	ENOG4105DH7	May be involved in recombination (By similarity)
AC609_21425	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
AC609_21430	ENOG4105C93	Xylose Isomerase
AC609_21435	ENOG4105ETE	Transcriptional regulator (LacI family
AC609_21440	ENOG4105D0H	Alpha-glucuronidase (EC 3.2.1.139)
AC609_21450	ENOG4105CXK	mandelate racemase muconate lactonizing
AC609_21465	ENOG4105DEI	Mannitol dehydrogenase
AC609_21520	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
AC609_21550	ENOG4105D9F	endo-1,4-beta-xylanase (EC 3.2.1.8)
AC609_21555	ENOG4105CNT	hydrolase family 2
AC609_21560	ENOG4105D2H	Uronic isomerase
AC609_21590	ENOG4105CT4	transporter
AC609_21595	ENOG4105DT9	hydrolase family 43
AC609_21660	ENOG4105E55	glycerol-3-phosphate acyltransferase
AC609_21670	ENOG4105ETE	Transcriptional regulator (LacI family
AC609_21690	ENOG4105QV4	Tryptophan halogenase
AC609_21695	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
AC609_21700	ENOG4105CUR	5'-nucleotidase, lipoprotein e(p4) family
AC609_21705	ENOG4108YXG	UPF0502 protein
AC609_21715	ENOG4105CSA	Coproporphyrinogen iii oxidase
AC609_21770	ENOG4105C4R	Atp-dependent dna helicase
AC609_21775	ENOG4107104	thymidine kinase
AC609_21780	ENOG4105BZU	Histidine kinase
AC609_21785	ENOG4105DJ9	glucan biosynthesis protein
AC609_21805	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
AC609_21835	ENOG4105DKK	Benzoate
AC609_21860	ENOG4105DSB	aldose 1-epimerase
AC609_21870	ENOG4105K5B	UPF0225 protein
AC609_21935	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
AC609_21945	ENOG4105EMU	Dehydrogenase
AC609_21950	ENOG410642W	LysR family Transcriptional regulator
AC609_21960	ENOG4105CSH	Transporter
AC609_21965	ENOG4105DR8	Membrane
AC609_21975	ENOG4105Y49	secretion protein, HlyD family
AC609_21980	ENOG4105ZQC	membrane protein AaeX
AC609_21990	ENOG4105EUJ	GTP cyclohydrolase i
AC609_22010	ENOG4105D5G	Transposase
AC609_22020	ENOG4105EJ9	Membrane
AC609_22035	ENOG4105D5G	Transposase
AC609_22060	ENOG4105D3G	Pseudouridine synthase
AC609_22145	ENOG4108TN6	type iii secretion
AC609_22155	ENOG41075IY	surface presentation of antigens protein SpaP
AC609_22175	ENOG4108JIR	Flagellum-specific ATP synthase
AC609_22185	ENOG4108HR8	type iii secretion
AC609_22190	ENOG4108N8R	Invasion protein
AC609_22210	ENOG4105Y7Q	type iii secretion
AC609_22290	ENOG4105F2I	Transposase
AC609_22375	ENOG4105CMM	transposase
AC609_22400	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
AC609_22430	ENOG4105CBZ	Short-chain dehydrogenase reductase Sdr
AC609_22460	ENOG4105VDM	plasmid maintenance system antidote protein, xre family
AC609_22470	ENOG4107QYX	exodeoxyribonuclease v alpha
AC609_22475	ENOG4107QKA	exodeoxyribonuclease V beta
AC609_22480	ENOG4105DSY	exodeoxyribonuclease V, gamma
AC609_22515	ENOG4105DHJ	ABC, transporter
AC609_22520	ENOG4105CY3	ABC transporter, permease
AC609_22525	ENOG4107PE3	Mammalian cell entry related domain protein
AC609_22540	ENOG410903C	(LipO)protein
AC609_22555	ENOG4108V06	Glutathione peroxidase
AC609_22565	ENOG4107QSV	RmuC domain protein
AC609_22575	ENOG4105EJC	lysr family transcriptional regulator
AC609_22600	ENOG4105CUB	amino acid
AC609_22605	ENOG4105CWX	Alpha-1,2-mannosidase
AC609_22610	ENOG4105NRM	Membrane
AC609_22615	ENOG4105BZU	Histidine kinase
AC609_22620	ENOG4108IXP	Carbohydrate diacid transcriptional activator CdaR
AC609_22625	ENOG4105BZW	Glycerate kinase
AC609_22645	ENOG4105DR4	Methyltransferase
AC609_22650	ENOG4105DU1	integral membrane protein, terc
AC609_22660	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
AC609_22680	ENOG4108ZJ4	polysaccharide deacetylase
AC609_22685	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
AC609_22690	ENOG41067YR	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
AC609_22735	ENOG4105XEZ	This methylase recognizes the double-stranded sequence TCGA, causes specific methylation on A-4 on both strands and protects the DNA from cleavage by the
AC609_22810	ENOG4105D5G	Transposase
AC609_22860	ENOG4108C33	Resolvase
AC609_22885	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
AC609_23055	ENOG4106H6R	UPF0380 protein
AC609_23105	ENOG4105F2I	Transposase
AC609_23130	ENOG4105D5G	Transposase
AC609_23175	ENOG4105D5G	Transposase
AC609_23240	ENOG4108C33	Resolvase
AC609_23320	ENOG4108ZUW	Major pilin subunit
AC609_23345	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)