locus-tag	class	description
AC609_00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AC609_00020	COG0187	DNA topoisomerase II activity
AC609_00030	COG0501	Belongs to the peptidase M48B family
AC609_00080	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AC609_00135	COG0793	Belongs to the peptidase S41A family
AC609_00140	COG4942	peptidase
AC609_00150	COG2234	aminopeptidase activity
AC609_00160	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
AC609_00165	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
AC609_00175	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
AC609_00180	COG1064	alcohol dehydrogenase
AC609_00190	COG0493	'glutamate synthase
AC609_00195	COG0070	glutamate synthase
AC609_00195	COG0069	glutamate synthase activity
AC609_00195	COG0067	glutamate synthase
AC609_00280	COG1111	helicase
AC609_00280	COG1205	dead DEAH box helicase
AC609_00285	COG1272	protein, Hemolysin III
AC609_00295	COG0300	oxidoreductase activity
AC609_00300	COG1028	Short-chain dehydrogenase reductase Sdr
AC609_00330	COG2249	NAD(P)H dehydrogenase (quinone) activity
AC609_00335	COG2963	transposase activity
AC609_00340	COG3039	Transposase
AC609_00350	COG3039	Transposase
AC609_00365	COG3237	CsbD-like
AC609_00415	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AC609_00420	COG0477	Major facilitator Superfamily
AC609_00460	COG0714	Associated with various cellular activities
AC609_00500	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AC609_00510	COG4772	TonB-dependent receptor
AC609_00535	COG1304	FMN binding
AC609_00540	COG1755	Isoprenylcysteine carboxyl methyltransferase
AC609_00545	COG4585	Histidine kinase
AC609_00550	COG2197	response regulator
AC609_00575	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AC609_00580	COG3039	Transposase
AC609_00600	COG0366	Alpha amylase catalytic
AC609_00605	COG0366	Alpha amylase catalytic
AC609_00610	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AC609_00630	COG0657	acetylesterase activity
AC609_00630	COG2755	lipolytic protein G-D-S-L family
AC609_00640	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AC609_00655	COG3507	Belongs to the glycosyl hydrolase 43 family
AC609_00660	COG1609	Transcriptional regulator
AC609_00665	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
AC609_00670	COG1028	Short-chain dehydrogenase reductase Sdr
AC609_00680	COG2755	lipolytic protein G-D-S-L family
AC609_00690	COG3186	Phenylalanine-4-hydroxylase
AC609_00695	COG1522	sequence-specific DNA binding
AC609_00705	COG1752	Esterase of the alpha-beta hydrolase superfamily
AC609_00715	COG1119	ATPase activity
AC609_00730	COG1125	glycine betaine transport
AC609_00730	COG0517	IMP dehydrogenase activity
AC609_00745	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AC609_00775	COG0489	protein tyrosine kinase activity
AC609_00780	COG2062	phosphohistidine phosphatase, SixA
AC609_00790	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AC609_00830	COG1968	undecaprenyl-diphosphatase activity
AC609_00835	COG0174	glutamine synthetase
AC609_00840	COG0347	Belongs to the P(II) protein family
AC609_00845	COG0004	ammonium transporteR
AC609_00850	COG3852	Histidine kinase
AC609_00855	COG2204	response regulator
AC609_00860	COG2032	superoxide dismutase activity
AC609_00865	COG2032	superoxide dismutase activity
AC609_00880	COG0183	Belongs to the thiolase family
AC609_00915	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AC609_00920	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
AC609_00925	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AC609_00955	COG2205	protein histidine kinase activity
AC609_00980	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AC609_00995	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AC609_01000	COG3177	Filamentation induced by cAMP protein fic
AC609_01005	COG0596	Alpha beta hydrolase
AC609_01015	COG0318	PFAM AMP-dependent synthetase and ligase
AC609_01020	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AC609_01040	COG1181	Belongs to the D-alanine--D-alanine ligase family
AC609_01050	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AC609_01060	COG0564	pseudouridine synthase activity
AC609_01080	COG1446	asparaginase
AC609_01085	COG0339	signal peptide processing
AC609_01115	COG0475	glutathione-regulated potassium exporter activity
AC609_01125	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AC609_01130	COG2224	Isocitrate lyase
AC609_01135	COG3706	GGDEF domain
AC609_01150	COG3039	Transposase
AC609_01170	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AC609_01175	COG1960	acyl-CoA dehydrogenase activity
AC609_01245	COG0697	spore germination
AC609_01255	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AC609_01260	COG1846	Transcriptional regulator
AC609_01265	COG1764	response to oxidative stress
AC609_01285	COG2130	NADP-dependent
AC609_01300	COG1187	pseudouridine synthase activity
AC609_01310	COG1643	Atp-dependent helicase
AC609_01315	COG4807	Protein conserved in bacteria
AC609_01320	COG2351	hydroxyisourate hydrolase activity
AC609_01325	COG2072	flavoprotein involved in K transport
AC609_01345	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AC609_01355	COG0583	DNA-binding transcription factor activity
AC609_01390	COG2252	PERMEase
AC609_01415	COG0084	hydrolase, TatD family'
AC609_01430	COG0583	DNA-binding transcription factor activity
AC609_01435	COG2814	Major facilitator Superfamily
AC609_01450	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AC609_01455	COG1902	pentaerythritol trinitrate reductase activity
AC609_01475	COG0745	RESPONSE REGULATOR receiver
AC609_01480	COG2205	protein histidine kinase activity
AC609_01485	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AC609_01510	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AC609_01515	COG0583	DNA-binding transcription factor activity
AC609_01530	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AC609_01555	COG0702	epimerase
AC609_01560	COG1733	regulation of RNA biosynthetic process
AC609_01580	COG3328	transposase activity
AC609_01615	COG2963	transposase activity
AC609_01620	COG2801	Transposase and inactivated derivatives
AC609_01630	COG0129	dihydroxy-acid dehydratase activity
AC609_01650	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AC609_01705	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AC609_01710	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AC609_01735	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AC609_01750	COG3485	protocatechuate 3,4-dioxygenase
AC609_01755	COG3485	protocatechuate 3,4-dioxygenase
AC609_01765	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AC609_01770	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AC609_01780	COG1414	Transcriptional regulator
AC609_01800	COG0445	tRNA wobble uridine modification
AC609_01840	COG2267	carboxylic ester hydrolase activity
AC609_01850	COG0156	8-amino-7-oxononanoate synthase activity
AC609_01855	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AC609_01860	COG1040	competence protein
AC609_01865	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AC609_01885	COG3039	Transposase
AC609_01950	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AC609_02020	COG3264	Mechanosensitive ion channel
AC609_02020	COG1511	domain protein
AC609_02025	COG1368	sulfuric ester hydrolase activity
AC609_02030	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AC609_02035	COG2354	Protein conserved in bacteria
AC609_02040	COG0745	RESPONSE REGULATOR receiver
AC609_02040	COG3706	GGDEF domain
AC609_02045	COG0297	glycogen (starch) synthase activity
AC609_02050	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AC609_02055	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AC609_02080	COG0702	epimerase
AC609_02105	COG3328	transposase activity
AC609_02110	COG2963	transposase activity
AC609_02115	COG3039	Transposase
AC609_02120	COG1028	Short-chain dehydrogenase reductase Sdr
AC609_02155	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AC609_02160	COG1028	Short-chain dehydrogenase reductase Sdr
AC609_02170	COG0513	Belongs to the DEAD box helicase family
AC609_02175	COG0508	dehydrogenase complex catalyzes the overall conversion of
AC609_02190	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AC609_02200	COG3483	tryptophan 2,3-dioxygenase activity
AC609_02205	COG3104	oligopeptide transport
AC609_02230	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
AC609_02245	COG1320	monovalent cation:proton antiporter activity
AC609_02250	COG2212	antiporter activity
AC609_02260	COG0651	ATP synthesis coupled electron transport
AC609_02265	COG1006	Multisubunit Na H antiporter MnhC subunit
AC609_02270	COG2111	Na H antiporter
AC609_02270	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AC609_02290	COG3179	chitinase
AC609_02310	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AC609_02315	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AC609_02335	COG1597	lipid kinase activity
AC609_02360	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AC609_02365	COG0134	indole-3-glycerol-phosphate synthase activity
AC609_02375	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AC609_02380	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
AC609_02390	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
AC609_02395	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AC609_02400	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AC609_02415	COG1051	belongs to the nudix hydrolase family
AC609_02455	COG0316	Belongs to the HesB IscA family
AC609_02470	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
AC609_02485	COG2814	Major facilitator Superfamily
AC609_02495	COG2814	Major facilitator Superfamily
AC609_02500	COG1289	transmembrane transporter activity
AC609_02510	COG0151	Belongs to the GarS family
AC609_02520	COG0138	bifunctional purine biosynthesis protein purh
AC609_02525	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AC609_02530	COG2267	carboxylic ester hydrolase activity
AC609_02535	COG2453	phosphatase
AC609_02535	COG0671	phosphoesterase, PA-phosphatase related
AC609_02560	COG4589	Belongs to the CDS family
AC609_02565	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
AC609_02590	COG2264	protein methyltransferase activity
AC609_02605	COG0439	Biotin carboxylase
AC609_02615	COG0511	ligase activity, forming carbon-carbon bonds
AC609_02620	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AC609_02635	COG1324	tolerance protein
AC609_02645	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AC609_02650	COG0459	protein refolding
AC609_02665	COG3550	peptidyl-serine autophosphorylation
AC609_02670	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AC609_02690	COG3386	PFAM SMP-30 Gluconolaconase
AC609_02700	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AC609_02705	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AC609_02720	COG3039	Transposase
AC609_02735	COG0778	Nitroreductase
AC609_02740	COG2353	YceI-like domain
AC609_02775	COG3052	prosthetic group binding
AC609_02795	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
AC609_02800	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AC609_02810	COG1802	Transcriptional regulator
AC609_02860	COG3328	transposase activity
AC609_02870	COG4221	oxidoreductase activity
AC609_02895	COG4221	oxidoreductase activity
AC609_02905	COG0435	Glutathione S-transferase
AC609_02955	COG3706	GGDEF domain
AC609_02960	COG1959	2 iron, 2 sulfur cluster binding
AC609_02985	COG0697	spore germination
AC609_02990	COG4305	rare lipoprotein A
AC609_03000	COG5297	Belongs to the glycosyl hydrolase family 6
AC609_03015	COG1113	amino acid transport
AC609_03025	COG0598	Magnesium transport protein CorA
AC609_03035	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
AC609_03075	COG2205	protein histidine kinase activity
AC609_03075	COG0784	Response regulator, receiver
AC609_03090	COG5297	Belongs to the glycosyl hydrolase family 6
AC609_03090	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
AC609_03120	COG2943	transferase activity, transferring hexosyl groups
AC609_03130	COG3275	phosphorelay sensor kinase activity
AC609_03140	COG0181	hydroxymethylbilane synthase activity
AC609_03175	COG1505	serine-type exopeptidase activity
AC609_03195	COG2832	Protein of unknown function (DUF454)
AC609_03205	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AC609_03215	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AC609_03220	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AC609_03225	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AC609_03250	COG2226	methyltransferase
AC609_03255	COG5001	Diguanylate cyclase
AC609_03255	COG3300	MHYT domain
AC609_03260	COG0308	aminopeptidase N
AC609_03310	COG3284	Transcriptional regulator
AC609_03330	COG1077	Cell shape determining protein MreB Mrl
AC609_03335	COG1792	Involved in formation and maintenance of cell shape
AC609_03350	COG0772	Belongs to the SEDS family
AC609_03360	COG3039	Transposase
AC609_03385	COG2951	lytic endotransglycosylase activity
AC609_03390	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AC609_03395	COG1686	Belongs to the peptidase S11 family
AC609_03405	COG2921	Belongs to the UPF0250 family
AC609_03410	COG0321	lipoyl(octanoyl) transferase activity
AC609_03415	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AC609_03440	COG1056	cytidyltransferase-related domain
AC609_03440	COG1051	belongs to the nudix hydrolase family
AC609_03475	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
AC609_03480	COG0673	inositol 2-dehydrogenase activity
AC609_03485	COG2823	Periplasmic or secreted lipoprotein
AC609_03490	COG4251	negative regulation of phosphorylation
AC609_03495	COG0784	Response regulator, receiver
AC609_03500	COG4191	Histidine kinase
AC609_03505	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AC609_03560	COG1459	type II secretion system
AC609_03615	COG1609	Transcriptional regulator
AC609_03620	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AC609_03625	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AC609_03635	COG0617	tRNA 3'-terminal CCA addition
AC609_03650	COG0525	valine-tRNA ligase activity
AC609_03665	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AC609_03675	COG0795	lipopolysaccharide-transporting ATPase activity
AC609_03690	COG4974	Belongs to the 'phage' integrase family
AC609_03695	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AC609_03700	COG0047	phosphoribosylformylglycinamidine synthase activity
AC609_03700	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AC609_03710	COG5295	Hep Hag repeat protein
AC609_03715	COG1404	Belongs to the peptidase S8 family
AC609_03720	COG5295	Hep Hag repeat protein
AC609_03725	COG1404	Belongs to the peptidase S8 family
AC609_03730	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AC609_03735	COG1459	type II secretion system
AC609_03740	COG2165	general secretion pathway protein
AC609_03745	COG4970	Tfp pilus assembly protein FimT
AC609_03750	COG2165	general secretion pathway protein
AC609_03755	COG4795	General secretion pathway protein
AC609_03760	COG3156	type II secretion system protein K
AC609_03765	COG3166	PFAM Fimbrial assembly family protein
AC609_03780	COG1450	Type ii and iii secretion system protein
AC609_03790	COG2188	Transcriptional regulator
AC609_03850	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AC609_03865	COG1215	transferase activity, transferring glycosyl groups
AC609_03870	COG1215	transferase activity, transferring glycosyl groups
AC609_03875	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
AC609_03905	COG0242	peptide deformylase activity
AC609_03910	COG0488	(ABC) transporter
AC609_03920	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AC609_03925	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AC609_03935	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AC609_03935	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AC609_03945	COG3328	transposase activity
AC609_03965	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AC609_03970	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AC609_03975	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AC609_03990	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
AC609_03995	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
AC609_04005	COG2205	protein histidine kinase activity
AC609_04010	COG0745	RESPONSE REGULATOR receiver
AC609_04020	COG0277	FAD linked oxidase domain protein
AC609_04025	COG1988	membrane-bound metal-dependent
AC609_04030	COG0792	nuclease activity
AC609_04055	COG2001	Belongs to the MraZ family
AC609_04065	COG3116	cell division
AC609_04075	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AC609_04080	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AC609_04085	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AC609_04095	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AC609_04100	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AC609_04105	COG1181	Belongs to the D-alanine--D-alanine ligase family
AC609_04110	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AC609_04125	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
AC609_04135	COG0739	heme binding
AC609_04140	COG0653	protein targeting
AC609_04145	COG0494	nUDIX hydrolase
AC609_04155	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AC609_04165	COG1028	Short-chain dehydrogenase reductase Sdr
AC609_04165	COG3321	synthase
AC609_04165	COG0604	alcohol dehydrogenase
AC609_04185	COG0366	Alpha amylase catalytic
AC609_04220	COG2226	methyltransferase
AC609_04225	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AC609_04235	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AC609_04275	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AC609_04285	COG4106	trans-aconitate 2-methyltransferase activity
AC609_04290	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AC609_04300	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AC609_04305	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AC609_04310	COG0667	Aldo Keto reductase
AC609_04320	COG4771	TonB-dependent receptor
AC609_04340	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AC609_04345	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AC609_04355	COG2175	clavaminate synthase activity
AC609_04365	COG4181	ATPase activity
AC609_04380	COG0642	Histidine kinase
AC609_04390	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AC609_04400	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
AC609_04410	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AC609_04415	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AC609_04430	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AC609_04435	COG2967	ApaG domain
AC609_04445	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AC609_04450	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AC609_04455	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AC609_04465	COG0123	including yeast histone deacetylase and acetoin utilization protein
AC609_04470	COG2096	Adenosyltransferase
AC609_04480	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AC609_04485	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AC609_04515	COG3384	dioxygenase
AC609_04520	COG0583	DNA-binding transcription factor activity
AC609_04525	COG0318	PFAM AMP-dependent synthetase and ligase
AC609_04535	COG1024	Enoyl-CoA hydratase
AC609_04555	COG3386	PFAM SMP-30 Gluconolaconase
AC609_04565	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
AC609_04590	COG0697	spore germination
AC609_04600	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AC609_04615	COG3706	GGDEF domain
AC609_04615	COG0745	RESPONSE REGULATOR receiver
AC609_04625	COG2197	response regulator
AC609_04635	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AC609_04645	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AC609_04650	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AC609_04655	COG0583	DNA-binding transcription factor activity
AC609_04660	COG3634	alkyl hydroperoxide reductase activity
AC609_04670	COG2890	protein-(glutamine-N5) methyltransferase activity
AC609_04690	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AC609_04690	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AC609_04745	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AC609_04750	COG1404	Belongs to the peptidase S8 family
AC609_04755	COG1404	Belongs to the peptidase S8 family
AC609_04760	COG1404	Belongs to the peptidase S8 family
AC609_04765	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AC609_04790	COG1295	ribonuclease BN
AC609_04795	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AC609_04800	COG1254	Belongs to the acylphosphatase family
AC609_04815	COG0521	Mo-molybdopterin cofactor biosynthetic process
AC609_04825	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AC609_04830	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AC609_04840	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
AC609_04845	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AC609_04855	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AC609_04860	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AC609_04865	COG0193	aminoacyl-tRNA hydrolase activity
AC609_04870	COG0012	GTP binding
AC609_04890	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AC609_04900	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AC609_04905	COG0250	Participates in transcription elongation, termination and antitermination
AC609_04910	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AC609_04915	COG0081	regulation of translation
AC609_04920	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AC609_04930	COG0085	RNA polymerase activity
AC609_04935	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AC609_04940	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AC609_04945	COG0049	tRNA binding
AC609_04950	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AC609_04955	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AC609_04965	COG3328	transposase activity
AC609_04970	COG0051	transcription antitermination factor activity, RNA binding
AC609_04975	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AC609_04980	COG0088	Forms part of the polypeptide exit tunnel
AC609_04985	COG0089	rRNA binding
AC609_04990	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AC609_04995	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AC609_05000	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AC609_05005	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AC609_05010	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AC609_05015	COG0255	Belongs to the universal ribosomal protein uL29 family
AC609_05020	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AC609_05025	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AC609_05030	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AC609_05035	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AC609_05040	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AC609_05045	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AC609_05050	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AC609_05055	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AC609_05060	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AC609_05065	COG1841	ribosomal large subunit assembly
AC609_05070	COG0200	Binds to the 23S rRNA
AC609_05075	COG0201	protein transport
AC609_05080	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AC609_05085	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AC609_05090	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AC609_05095	COG0202	RNA polymerase activity
AC609_05100	COG0203	ribosomal protein L17
AC609_05105	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AC609_05125	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
AC609_05135	COG0154	amidase activity
AC609_05150	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AC609_05155	COG0039	L-malate dehydrogenase activity
AC609_05160	COG0625	glutathione transferase activity
AC609_05170	COG1902	pentaerythritol trinitrate reductase activity
AC609_05170	COG0446	pyridine nucleotide-disulphide oxidoreductase
AC609_05175	COG0604	alcohol dehydrogenase
AC609_05180	COG3328	transposase activity
AC609_05185	COG3039	Transposase
AC609_05190	COG2885	chlorophyll binding
AC609_05210	COG0156	8-amino-7-oxononanoate synthase activity
AC609_05215	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AC609_05220	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AC609_05225	COG4208	sulfate ABC transporter
AC609_05230	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AC609_05240	COG3328	transposase activity
AC609_05245	COG1063	alcohol dehydrogenase
AC609_05265	COG0406	alpha-ribazole phosphatase activity
AC609_05275	COG0285	dihydrofolate synthase activity
AC609_05295	COG2833	Protein of unknown function (DUF455)
AC609_05310	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AC609_05315	COG0671	phosphoesterase, PA-phosphatase related
AC609_05320	COG0438	transferase activity, transferring glycosyl groups
AC609_05330	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AC609_05345	COG4783	chaperone-mediated protein folding
AC609_05360	COG0473	3-isopropylmalate dehydrogenase activity
AC609_05395	COG3328	transposase activity
AC609_05410	COG0544	peptidyl-prolyl cis-trans isomerase activity
AC609_05415	COG0740	serine-type endopeptidase activity
AC609_05420	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AC609_05450	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AC609_05460	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AC609_05470	COG0328	RNA-DNA hybrid ribonuclease activity
AC609_05475	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AC609_05480	COG0631	protein serine/threonine phosphatase activity
AC609_05495	COG0859	PFAM glycosyl transferase family 9
AC609_05500	COG3642	lipopolysaccharide core region biosynthetic process
AC609_05505	COG1234	tRNA 3'-trailer cleavage
AC609_05510	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AC609_05520	COG0315	cyclic pyranopterin monophosphate synthase activity
AC609_05525	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AC609_05530	COG0314	molybdopterin synthase activity
AC609_05545	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AC609_05550	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AC609_05555	COG0537	adenosine 5'-monophosphoramidase activity
AC609_05575	COG0714	Associated with various cellular activities
AC609_05585	COG0424	maF-like protein
AC609_05590	COG1399	metal-binding, possibly nucleic acid-binding protein
AC609_05595	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AC609_05600	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AC609_05615	COG1028	Short-chain dehydrogenase reductase Sdr
AC609_05620	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AC609_05630	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AC609_05635	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AC609_05670	COG3829	transcription factor binding
AC609_05710	COG2373	Large extracellular alpha-helical protein
AC609_05730	COG3852	Histidine kinase
AC609_05735	COG4953	penicillin-binding protein 1C
AC609_05745	COG0678	peroxiredoxin activity
AC609_05765	COG0330	HflC and HflK could
AC609_05770	COG0330	HflC and HflK could
AC609_05780	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AC609_05785	COG0308	aminopeptidase N
AC609_05795	COG1028	Short-chain dehydrogenase reductase Sdr
AC609_05800	COG1309	transcriptional regulator
AC609_05850	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AC609_05860	COG3387	PFAM Glycoside hydrolase 15-related
AC609_05865	COG1028	Short-chain dehydrogenase reductase Sdr
AC609_05870	COG3537	Alpha-1,2-mannosidase
AC609_05895	COG0492	ferredoxin-NADP+ reductase activity
AC609_05930	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AC609_05935	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AC609_05940	COG2080	2 iron, 2 sulfur cluster binding
AC609_05975	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AC609_05995	COG0587	DNA-directed DNA polymerase activity
AC609_06010	COG1297	OPT oligopeptide transporter protein
AC609_06035	COG1506	peptidase
AC609_06035	COG0823	Involved in the tonB-independent uptake of proteins
AC609_06055	COG2207	Transcriptional regulator
AC609_06055	COG1917	Cupin 2, conserved barrel domain protein
AC609_06070	COG3328	transposase activity
AC609_06080	COG0753	catalase activity
AC609_06085	COG0656	L-ascorbic acid biosynthetic process
AC609_06095	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AC609_06095	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AC609_06120	COG2814	Major facilitator Superfamily
AC609_06130	COG2801	Transposase and inactivated derivatives
AC609_06160	COG2194	sulfuric ester hydrolase activity
AC609_06175	COG0745	RESPONSE REGULATOR receiver
AC609_06180	COG0642	Histidine kinase
AC609_06190	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
AC609_06195	COG2894	cell division
AC609_06200	COG0850	regulation of cytokinetic process
AC609_06210	COG4585	Histidine kinase
AC609_06215	COG2197	response regulator
AC609_06235	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AC609_06260	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AC609_06270	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
AC609_06285	COG1595	DNA-templated transcription, initiation
AC609_06295	COG1946	Acyl-CoA thioesterase
AC609_06310	COG0824	Thioesterase
AC609_06315	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AC609_06320	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AC609_06325	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AC609_06330	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AC609_06335	COG0268	Binds directly to 16S ribosomal RNA
AC609_06345	COG0196	riboflavin kinase activity
AC609_06350	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AC609_06355	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AC609_06360	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AC609_06465	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
AC609_06465	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AC609_06505	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AC609_06510	COG1845	cytochrome c oxidase, subunit III
AC609_06515	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AC609_06530	COG3152	Membrane
AC609_06540	COG2207	Transcriptional regulator
AC609_06545	COG0326	Molecular chaperone. Has ATPase activity
AC609_06555	COG1366	Belongs to the anti-sigma-factor antagonist family
AC609_06560	COG1366	Belongs to the anti-sigma-factor antagonist family
AC609_06590	COG4771	TonB-dependent receptor
AC609_06600	COG5507	3-demethylubiquinone-9 3-methyltransferase
AC609_06605	COG2205	protein histidine kinase activity
AC609_06615	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AC609_06620	COG3850	Histidine kinase
AC609_06620	COG4999	Histidine kinase
AC609_06620	COG3437	response regulator, receiver
AC609_06620	COG2205	protein histidine kinase activity
AC609_06625	COG4191	Histidine kinase
AC609_06625	COG0784	Response regulator, receiver
AC609_06655	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AC609_06670	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AC609_06675	COG0228	four-way junction DNA binding
AC609_06680	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AC609_06685	COG0336	Belongs to the RNA methyltransferase TrmD family
AC609_06690	COG0335	large ribosomal subunit rRNA binding
AC609_06695	COG0534	Mate efflux family protein
AC609_06720	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
AC609_06730	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AC609_06735	COG2801	Transposase and inactivated derivatives
AC609_06740	COG2963	transposase activity
AC609_06745	COG2963	transposase activity
AC609_06750	COG2801	Transposase and inactivated derivatives
AC609_06755	COG2801	Transposase and inactivated derivatives
AC609_06760	COG2963	transposase activity
AC609_06780	COG3250	beta-galactosidase activity
AC609_06785	COG3867	Arabinogalactan endo-beta-1,4-galactanase
AC609_06805	COG1960	acyl-CoA dehydrogenase activity
AC609_06835	COG0457	Tetratricopeptide repeat
AC609_06845	COG0457	Tetratricopeptide repeat
AC609_06855	COG1250	3-hydroxyacyl-CoA dehydrogenase
AC609_06855	COG1024	Enoyl-CoA hydratase
AC609_06870	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AC609_06875	COG0481	GTPase activity
AC609_06890	COG0571	ribonuclease III activity
AC609_06895	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AC609_06900	COG1381	Involved in DNA repair and RecF pathway recombination
AC609_06910	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AC609_06920	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AC609_06925	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
AC609_06930	COG3046	protein related to deoxyribodipyrimidine photolyase
AC609_06935	COG1472	Belongs to the glycosyl hydrolase 3 family
AC609_06945	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AC609_06950	COG1278	Cold shock
AC609_06955	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AC609_06965	COG1201	RNA secondary structure unwinding
AC609_06970	COG1793	dna ligase
AC609_06980	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AC609_06980	COG1793	dna ligase
AC609_06995	COG3706	GGDEF domain
AC609_06995	COG0745	RESPONSE REGULATOR receiver
AC609_07010	COG0183	Belongs to the thiolase family
AC609_07030	COG1451	nucleotide metabolic process
AC609_07035	COG5487	UPF0391 membrane protein
AC609_07045	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AC609_07065	COG1077	Cell shape determining protein MreB Mrl
AC609_07070	COG1047	Peptidyl-prolyl cis-trans
AC609_07080	COG2824	Alkylphosphonate utilization operon protein PhnA
AC609_07090	COG1902	pentaerythritol trinitrate reductase activity
AC609_07095	COG2814	Major facilitator Superfamily
AC609_07130	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
AC609_07130	COG0392	lysyltransferase activity
AC609_07140	COG0251	oxidation-reduction process
AC609_07145	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AC609_07160	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AC609_07185	COG1595	DNA-templated transcription, initiation
AC609_07205	COG2878	Part of a membrane complex involved in electron transport
AC609_07215	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AC609_07215	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AC609_07235	COG0346	lactoylglutathione lyase activity
AC609_07250	COG0833	amino acid
AC609_07255	COG2040	homocysteine
AC609_07265	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AC609_07285	COG1695	Transcriptional regulator
AC609_07320	COG0825	malonyl-CoA metabolic process
AC609_07335	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AC609_07340	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AC609_07345	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AC609_07350	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AC609_07365	COG0750	zinc metalloprotease
AC609_07370	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AC609_07375	COG0575	Belongs to the CDS family
AC609_07380	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AC609_07385	COG0233	cytoplasmic translational termination
AC609_07390	COG0528	UMP kinase activity
AC609_07395	COG3706	GGDEF domain
AC609_07395	COG0745	RESPONSE REGULATOR receiver
AC609_07400	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AC609_07405	COG0052	Belongs to the universal ribosomal protein uS2 family
AC609_07440	COG0024	Methionine aminopeptidase
AC609_07445	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AC609_07455	COG1393	Belongs to the ArsC family
AC609_07460	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AC609_07465	COG0367	asparagine synthase
AC609_07480	COG4774	siderophore transport
AC609_07525	COG2963	transposase activity
AC609_07530	COG2801	Transposase and inactivated derivatives
AC609_07535	COG3328	transposase activity
AC609_07570	COG1566	PFAM secretion protein HlyD family protein
AC609_07575	COG2814	Major facilitator Superfamily
AC609_07635	COG0339	signal peptide processing
AC609_07640	COG0386	Belongs to the glutathione peroxidase family
AC609_07700	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AC609_07705	COG0084	hydrolase, TatD family'
AC609_07720	COG1960	acyl-CoA dehydrogenase activity
AC609_07735	COG0367	asparagine synthase
AC609_07745	COG0305	Participates in initiation and elongation during chromosome replication
AC609_07750	COG0415	Belongs to the DNA photolyase family
AC609_07760	COG0583	DNA-binding transcription factor activity
AC609_07795	COG3706	GGDEF domain
AC609_07805	COG3706	GGDEF domain
AC609_07825	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AC609_07840	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AC609_07850	COG0497	DNA recombination
AC609_07855	COG1420	regulation of RNA biosynthetic process
AC609_07860	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AC609_07865	COG0443	Heat shock 70 kDa protein
AC609_07870	COG0484	heat shock protein binding
AC609_07875	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
AC609_07905	COG0583	DNA-binding transcription factor activity
AC609_07910	COG1132	(ABC) transporter
AC609_07945	COG2850	peptidyl-arginine hydroxylation
AC609_07965	COG1253	flavin adenine dinucleotide binding
AC609_07995	COG1131	(ABC) transporter
AC609_08000	COG1725	Transcriptional regulator
AC609_08005	COG0386	Belongs to the glutathione peroxidase family
AC609_08015	COG2900	Belongs to the SlyX family
AC609_08040	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AC609_08050	COG0646	methionine synthase
AC609_08050	COG1410	methionine synthase
AC609_08065	COG1960	acyl-CoA dehydrogenase activity
AC609_08080	COG0557	exoribonuclease II activity
AC609_08090	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AC609_08105	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AC609_08115	COG0704	Plays a role in the regulation of phosphate uptake
AC609_08120	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AC609_08125	COG0581	inorganic phosphate transmembrane transporter activity
AC609_08130	COG0573	inorganic phosphate transmembrane transporter activity
AC609_08135	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AC609_08160	COG0659	secondary active sulfate transmembrane transporter activity
AC609_08165	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AC609_08175	COG1024	Enoyl-CoA hydratase
AC609_08185	COG0494	nUDIX hydrolase
AC609_08230	COG0116	Belongs to the methyltransferase superfamily
AC609_08230	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AC609_08235	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AC609_08255	COG2925	Exonuclease
AC609_08260	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AC609_08265	COG3844	kynureninase activity
AC609_08275	COG0662	Cupin 2, conserved barrel domain protein
AC609_08280	COG0288	reversible hydration of carbon dioxide
AC609_08355	COG0017	Asparaginyl-tRNA synthetase
AC609_08360	COG0316	Belongs to the HesB IscA family
AC609_08365	COG0360	Binds together with S18 to 16S ribosomal RNA
AC609_08370	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AC609_08375	COG0359	binds to the 23S rRNA
AC609_08385	COG3115	cell septum assembly
AC609_08395	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AC609_08400	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AC609_08405	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
AC609_08415	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
AC609_08425	COG4993	Dehydrogenase
AC609_08435	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
AC609_08450	COG2986	histidine ammonia-lyase
AC609_08455	COG1228	amidohydrolase
AC609_08495	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
AC609_08500	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AC609_08505	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AC609_08510	COG0077	Prephenate dehydratase
AC609_08510	COG1605	Chorismate mutase
AC609_08515	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AC609_08530	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AC609_08535	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AC609_08540	COG0583	DNA-binding transcription factor activity
AC609_08605	COG0784	Response regulator, receiver
AC609_08605	COG4191	Histidine kinase
AC609_08615	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
AC609_08635	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AC609_08645	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
AC609_08655	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AC609_08670	COG1595	DNA-templated transcription, initiation
AC609_08720	COG2244	polysaccharide biosynthetic process
AC609_08750	COG2264	protein methyltransferase activity
AC609_08775	COG1136	(ABC) transporter
AC609_08785	COG0477	Major facilitator Superfamily
AC609_08790	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AC609_08805	COG1253	flavin adenine dinucleotide binding
AC609_08815	COG0306	phosphate transporter
AC609_08840	COG0504	CTP synthase activity
AC609_08845	COG2877	3-deoxy-8-phosphooctulonate synthase activity
AC609_08855	COG0148	phosphopyruvate hydratase activity
AC609_08860	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AC609_08870	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AC609_08875	COG0585	pseudouridine synthase activity
AC609_08880	COG2840	Smr protein MutS2
AC609_08885	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AC609_08890	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AC609_08895	COG1238	metal cluster binding
AC609_08905	COG3737	Protein of unknown function (DUF498/DUF598)
AC609_08910	COG1534	Rna-binding protein
AC609_08915	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AC609_08920	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AC609_08925	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AC609_08930	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AC609_08935	COG1923	regulation of RNA biosynthetic process
AC609_08940	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AC609_08945	COG1546	Belongs to the CinA family
AC609_08955	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AC609_08960	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AC609_08965	COG2137	regulation of response to DNA damage stimulus
AC609_08970	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AC609_08975	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
AC609_09000	COG0583	DNA-binding transcription factor activity
AC609_09025	COG0351	phosphomethylpyrimidine kinase
AC609_09040	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AC609_09045	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AC609_09060	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AC609_09070	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AC609_09075	COG3734	2-keto-3-deoxy-galactonokinase
AC609_09085	COG4948	Mandelate Racemase Muconate Lactonizing
AC609_09090	COG0800	Aldolase
AC609_09130	COG1501	Belongs to the glycosyl hydrolase 31 family
AC609_09140	COG1070	Carbohydrate kinase
AC609_09145	COG2115	Belongs to the xylose isomerase family
AC609_09150	COG0477	Major facilitator Superfamily
AC609_09160	COG3328	transposase activity
AC609_09175	COG0860	N-Acetylmuramoyl-L-alanine amidase
AC609_09180	COG1469	GTP cyclohydrolase I activity
AC609_09205	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AC609_09210	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AC609_09215	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AC609_09220	COG0166	Belongs to the GPI family
AC609_09240	COG1472	Belongs to the glycosyl hydrolase 3 family
AC609_09250	COG5001	Diguanylate cyclase
AC609_09250	COG4251	negative regulation of phosphorylation
AC609_09250	COG3706	GGDEF domain
AC609_09250	COG2203	Gaf domain
AC609_09260	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
AC609_09265	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
AC609_09275	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AC609_09280	COG0671	phosphoesterase, PA-phosphatase related
AC609_09290	COG1794	racemase activity, acting on amino acids and derivatives
AC609_09295	COG0697	spore germination
AC609_09300	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AC609_09305	COG0167	dihydroorotate dehydrogenase activity
AC609_09320	COG1012	belongs to the aldehyde dehydrogenase family
AC609_09335	COG3328	transposase activity
AC609_09340	COG3328	transposase activity
AC609_09345	COG0366	Alpha amylase catalytic
AC609_09360	COG1082	Xylose isomerase domain protein TIM barrel
AC609_09370	COG2211	Major facilitator Superfamily
AC609_09385	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AC609_09390	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AC609_09395	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AC609_09400	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AC609_09405	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AC609_09410	COG0072	phenylalanine-tRNA ligase activity
AC609_09410	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AC609_09415	COG0776	regulation of translation
AC609_09460	COG0438	transferase activity, transferring glycosyl groups
AC609_09465	COG0438	transferase activity, transferring glycosyl groups
AC609_09500	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AC609_09510	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AC609_09530	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AC609_09540	COG1960	acyl-CoA dehydrogenase activity
AC609_09550	COG3040	lipid binding
AC609_09565	COG0322	excinuclease ABC activity
AC609_09580	COG4191	Histidine kinase
AC609_09580	COG0784	Response regulator, receiver
AC609_09600	COG1194	a g-specific adenine glycosylase
AC609_09605	COG0552	protein localization to endoplasmic reticulum
AC609_09615	COG3938	Belongs to the proline racemase family
AC609_09620	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AC609_09635	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AC609_09645	COG0006	proline dipeptidase activity
AC609_09660	COG0531	amino acid
AC609_09775	COG3328	transposase activity
AC609_09820	COG3328	transposase activity
AC609_09830	COG2801	Transposase and inactivated derivatives
AC609_09835	COG2963	transposase activity
AC609_09840	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
AC609_09845	COG3328	transposase activity
AC609_09850	COG0460	homoserine dehydrogenase
AC609_09850	COG0527	aspartate kinase activity
AC609_09885	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AC609_09890	COG0124	histidyl-tRNA synthetase
AC609_09905	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AC609_09910	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AC609_09915	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AC609_09920	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AC609_09920	COG0131	Imidazoleglycerol-phosphate dehydratase
AC609_09925	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AC609_09930	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AC609_09935	COG0107	imidazoleglycerol-phosphate synthase activity
AC609_09940	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AC609_09940	COG0140	phosphoribosyl-ATP diphosphatase activity
AC609_09955	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
AC609_09960	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
AC609_09965	COG0235	Class ii aldolase
AC609_09970	COG0531	amino acid
AC609_09975	COG0531	amino acid
AC609_09985	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AC609_09990	COG0277	FAD linked oxidase domain protein
AC609_10010	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AC609_10055	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AC609_10060	COG2258	MOSC domain
AC609_10065	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AC609_10070	COG0505	Belongs to the CarA family
AC609_10080	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AC609_10085	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AC609_10095	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AC609_10110	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AC609_10115	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AC609_10130	COG2205	protein histidine kinase activity
AC609_10130	COG0784	Response regulator, receiver
AC609_10130	COG2198	Histidine kinase
AC609_10135	COG1024	Enoyl-CoA hydratase
AC609_10140	COG0318	PFAM AMP-dependent synthetase and ligase
AC609_10175	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AC609_10185	COG2201	protein-glutamate methylesterase activity
AC609_10190	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
AC609_10200	COG0840	transmembrane signaling receptor activity
AC609_10210	COG0835	chemotaxis
AC609_10220	COG0840	transmembrane signaling receptor activity
AC609_10225	COG0840	transmembrane signaling receptor activity
AC609_10230	COG0840	transmembrane signaling receptor activity
AC609_10235	COG0840	transmembrane signaling receptor activity
AC609_10240	COG0840	transmembrane signaling receptor activity
AC609_10250	COG0840	transmembrane signaling receptor activity
AC609_10255	COG0840	transmembrane signaling receptor activity
AC609_10260	COG0840	transmembrane signaling receptor activity
AC609_10265	COG0840	transmembrane signaling receptor activity
AC609_10275	COG0840	transmembrane signaling receptor activity
AC609_10280	COG0840	transmembrane signaling receptor activity
AC609_10290	COG0840	transmembrane signaling receptor activity
AC609_10295	COG0840	transmembrane signaling receptor activity
AC609_10305	COG0745	RESPONSE REGULATOR receiver
AC609_10315	COG0835	chemotaxis
AC609_10320	COG1192	Involved in chromosome partitioning
AC609_10325	COG1360	Flagellar Motor Protein
AC609_10330	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AC609_10370	COG0643	Histidine kinase
AC609_10370	COG2198	Histidine kinase
AC609_10390	COG0455	bacterial-type flagellum organization
AC609_10400	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AC609_10420	COG3039	Transposase
AC609_10430	COG1684	flagellar biosynthetic protein fliR
AC609_10435	COG1987	bacterial-type flagellum assembly
AC609_10440	COG3039	Transposase
AC609_10450	COG3190	flagellar
AC609_10500	COG1677	Flagellar hook-basal body complex protein FliE
AC609_10525	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AC609_10540	COG3328	transposase activity
AC609_10570	COG1028	Short-chain dehydrogenase reductase Sdr
AC609_10575	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AC609_10590	COG2204	response regulator
AC609_10595	COG2201	protein-glutamate methylesterase activity
AC609_10625	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
AC609_10635	COG3039	Transposase
AC609_10640	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AC609_10650	COG3951	Flagellar rod assembly protein muramidase FlgJ
AC609_10650	COG1705	Flagellar rod assembly protein muramidase FlgJ
AC609_10655	COG1706	bacterial-type flagellum-dependent cell motility
AC609_10660	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
AC609_10665	COG4786	Flagellar basal body rod
AC609_10680	COG4787	bacterial-type flagellum-dependent cell motility
AC609_10685	COG1749	Flagellar hook protein flgE
AC609_10690	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
AC609_10695	COG1558	bacterial-type flagellum-dependent cell motility
AC609_10705	COG0835	chemotaxis
AC609_10705	COG0784	Response regulator, receiver
AC609_10730	COG5002	protein histidine kinase activity
AC609_10740	COG4585	Histidine kinase
AC609_10760	COG2915	High frequency lysogenization protein hflD homolog
AC609_10765	COG0482	sulfurtransferase activity
AC609_10775	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AC609_10780	COG0542	response to heat
AC609_10785	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AC609_10790	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AC609_10800	COG0492	ferredoxin-NADP+ reductase activity
AC609_10805	COG1674	ftsk spoiiie
AC609_10815	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AC609_10825	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AC609_10830	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AC609_10835	COG0183	Belongs to the thiolase family
AC609_10840	COG1024	Enoyl-CoA hydratase
AC609_10840	COG1250	3-hydroxyacyl-CoA dehydrogenase
AC609_10850	COG0105	UTP biosynthetic process
AC609_10875	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AC609_10880	COG1160	GTP binding
AC609_10885	COG0303	'Molybdopterin
AC609_10890	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AC609_10925	COG0708	Exodeoxyribonuclease III
AC609_10935	COG0303	'Molybdopterin
AC609_10940	COG0746	molybdenum cofactor guanylyltransferase activity
AC609_10965	COG1648	precorrin-2 dehydrogenase activity
AC609_10965	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AC609_10975	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AC609_10980	COG2223	nitrite transmembrane transporter activity
AC609_10985	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AC609_10995	COG0243	molybdopterin cofactor binding
AC609_11010	COG3685	Protein conserved in bacteria
AC609_11030	COG5001	Diguanylate cyclase
AC609_11040	COG4566	intracellular signal transduction
AC609_11090	COG3328	transposase activity
AC609_11100	COG3039	Transposase
AC609_11105	COG3328	transposase activity
AC609_11115	COG3328	transposase activity
AC609_11125	COG1073	alpha beta
AC609_11125	COG2226	methyltransferase
AC609_11140	COG0363	glucosamine-6-phosphate deaminase activity
AC609_11160	COG3328	transposase activity
AC609_11235	COG3328	transposase activity
AC609_11245	COG1192	Involved in chromosome partitioning
AC609_11290	COG3318	Belongs to the UPF0149 family
AC609_11290	COG3012	SEC-C Motif Domain Protein
AC609_11330	COG3328	transposase activity
AC609_11360	COG1309	transcriptional regulator
AC609_11375	COG2154	pterin-4-alpha-carbinolamine dehydratase
AC609_11385	COG0428	transporter
AC609_11390	COG3064	Membrane
AC609_11400	COG1530	ribonuclease E activity
AC609_11405	COG3039	Transposase
AC609_11435	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AC609_11460	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AC609_11465	COG0322	excinuclease ABC activity
AC609_11475	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AC609_11480	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AC609_11485	COG1663	tetraacyldisaccharide 4'-kinase activity
AC609_11490	COG1132	(ABC) transporter
AC609_11500	COG0811	peptide transport
AC609_11515	COG1136	(ABC) transporter
AC609_11520	COG4591	ABC-type transport system involved in lipoprotein release permease component
AC609_11530	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AC609_11535	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AC609_11550	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AC609_11560	COG0354	folic acid binding
AC609_11570	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AC609_11575	COG0837	glucose binding
AC609_11580	COG0363	glucosamine-6-phosphate deaminase activity
AC609_11585	COG0129	dihydroxy-acid dehydratase activity
AC609_11590	COG0800	Aldolase
AC609_11660	COG0784	Response regulator, receiver
AC609_11660	COG2205	protein histidine kinase activity
AC609_11665	COG2183	response to ionizing radiation
AC609_11675	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AC609_11675	COG0723	plastoquinol--plastocyanin reductase activity
AC609_11690	COG3243	poly(R)-hydroxyalkanoic acid synthase
AC609_11700	COG1183	phosphatidylcholine synthase activity
AC609_11705	COG1028	Short-chain dehydrogenase reductase Sdr
AC609_11720	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AC609_11735	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AC609_11740	COG0590	tRNA wobble adenosine to inosine editing
AC609_11745	COG1321	iron dependent repressor
AC609_11750	COG1914	H( )-stimulated, divalent metal cation uptake system
AC609_11770	COG2814	Major facilitator Superfamily
AC609_11785	COG1335	isochorismatase
AC609_11805	COG2197	response regulator
AC609_11840	COG0583	DNA-binding transcription factor activity
AC609_11845	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AC609_11850	COG3002	Belongs to the UPF0753 family
AC609_11860	COG0604	alcohol dehydrogenase
AC609_11865	COG3384	dioxygenase
AC609_11875	COG2801	Transposase and inactivated derivatives
AC609_11880	COG2963	transposase activity
AC609_11925	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AC609_11925	COG0519	Catalyzes the synthesis of GMP from XMP
AC609_11935	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AC609_11945	COG0475	glutathione-regulated potassium exporter activity
AC609_11945	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AC609_11950	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AC609_11960	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AC609_11965	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
AC609_11975	COG0776	regulation of translation
AC609_11980	COG0539	negative regulation of cytoplasmic translation
AC609_11985	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AC609_11990	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AC609_12000	COG2957	Belongs to the agmatine deiminase family
AC609_12005	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AC609_12030	COG0395	ABC-type sugar transport system, permease component
AC609_12035	COG1175	transmembrane transport
AC609_12070	COG2350	Protein conserved in bacteria
AC609_12075	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AC609_12080	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AC609_12085	COG1187	pseudouridine synthase activity
AC609_12100	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AC609_12105	COG0436	Aminotransferase
AC609_12110	COG4133	protoheme IX ABC transporter activity
AC609_12130	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
AC609_12155	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AC609_12165	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AC609_12170	COG4988	ABC transporter
AC609_12180	COG1294	oxidase, subunit
AC609_12210	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AC609_12215	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AC609_12225	COG0165	Argininosuccinate lyase
AC609_12230	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AC609_12240	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AC609_12255	COG0137	argininosuccinate synthase activity
AC609_12260	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AC609_12270	COG0215	cysteine-tRNA ligase activity
AC609_12275	COG2166	iron-sulfur cluster assembly
AC609_12285	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AC609_12295	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AC609_12300	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AC609_12325	COG4302	ethanolamine ammonia-lyase activity
AC609_12350	COG3039	Transposase
AC609_12380	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AC609_12385	COG0402	S-adenosylhomocysteine deaminase activity
AC609_12395	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AC609_12400	COG1509	lysine 2,3-aminomutase activity
AC609_12405	COG5001	Diguanylate cyclase
AC609_12405	COG3300	MHYT domain
AC609_12420	COG0483	inositol monophosphate 1-phosphatase activity
AC609_12445	COG0513	Belongs to the DEAD box helicase family
AC609_12450	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AC609_12455	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AC609_12475	COG0625	glutathione transferase activity
AC609_12485	COG4681	YaeQ
AC609_12490	COG2081	HI0933 family
AC609_12500	COG0501	Belongs to the peptidase M48B family
AC609_12505	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AC609_12510	COG1028	Short-chain dehydrogenase reductase Sdr
AC609_12530	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AC609_12535	COG0860	N-Acetylmuramoyl-L-alanine amidase
AC609_12540	COG0802	atpase or kinase
AC609_12545	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AC609_12545	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AC609_12550	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AC609_12555	COG1570	exodeoxyribonuclease VII activity
AC609_12565	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AC609_12605	COG0835	chemotaxis
AC609_12610	COG0840	transmembrane signaling receptor activity
AC609_12615	COG2094	Belongs to the DNA glycosylase MPG family
AC609_12620	COG1201	RNA secondary structure unwinding
AC609_12635	COG2969	positive regulation of protein catabolic process
AC609_12640	COG0625	glutathione transferase activity
AC609_12645	COG2857	Cytochrome c1
AC609_12650	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AC609_12655	COG0723	plastoquinol--plastocyanin reductase activity
AC609_12665	COG0741	lytic transglycosylase activity
AC609_12680	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AC609_12685	COG1702	phosphate starvation-inducible protein PhoH
AC609_12695	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AC609_12705	COG4535	Mg2 and Co2 transporter CorC
AC609_12720	COG1012	belongs to the aldehyde dehydrogenase family
AC609_12730	COG1177	transmembrane transport
AC609_12735	COG1176	ABC-type spermidine putrescine transport system, permease component I
AC609_12740	COG3842	ATPase activity
AC609_12760	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AC609_12775	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AC609_12780	COG0174	glutamine synthetase
AC609_12785	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AC609_12790	COG3706	GGDEF domain
AC609_12790	COG0745	RESPONSE REGULATOR receiver
AC609_12795	COG2703	oxygen carrier activity
AC609_12800	COG0477	Major facilitator Superfamily
AC609_12810	COG0243	molybdopterin cofactor binding
AC609_12815	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AC609_12835	COG2733	membrane
AC609_12840	COG2205	protein histidine kinase activity
AC609_12840	COG5002	protein histidine kinase activity
AC609_12840	COG0784	Response regulator, receiver
AC609_12850	COG0477	Major facilitator Superfamily
AC609_12855	COG0840	transmembrane signaling receptor activity
AC609_12885	COG2902	Dehydrogenase
AC609_12895	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AC609_12900	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AC609_12905	COG1609	Transcriptional regulator
AC609_12910	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AC609_12910	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AC609_12915	COG1105	Belongs to the carbohydrate kinase PfkB family
AC609_12920	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AC609_12920	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AC609_12935	COG3328	transposase activity
AC609_12940	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AC609_12950	COG1862	Preprotein translocase
AC609_12955	COG0343	queuine tRNA-ribosyltransferase activity
AC609_12960	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AC609_13005	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AC609_13010	COG3291	Pkd domain containing protein
AC609_13020	COG0405	Gamma-glutamyltransferase
AC609_13025	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AC609_13040	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AC609_13045	COG0742	ribosomal rna small subunit methyltransferase
AC609_13050	COG0326	Molecular chaperone. Has ATPase activity
AC609_13095	COG3328	transposase activity
AC609_13160	COG2948	multi-organism process
AC609_13180	COG3505	Type IV secretory pathway VirD4
AC609_13195	COG0556	nucleotide-excision repair
AC609_13265	COG2801	Transposase and inactivated derivatives
AC609_13270	COG2963	transposase activity
AC609_13365	COG3179	chitinase
AC609_13410	COG4695	Portal protein
AC609_13435	COG2963	transposase activity
AC609_13440	COG2801	Transposase and inactivated derivatives
AC609_13490	COG3275	phosphorelay sensor kinase activity
AC609_13495	COG1611	Belongs to the LOG family
AC609_13505	COG2095	MarC family integral membrane protein
AC609_13515	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AC609_13520	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AC609_13550	COG1185	polyribonucleotide nucleotidyltransferase activity
AC609_13555	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AC609_13560	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AC609_13565	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AC609_13570	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AC609_13575	COG0195	Participates in both transcription termination and antitermination
AC609_13580	COG0779	Required for maturation of 30S ribosomal subunits
AC609_13590	COG1007	ATP synthesis coupled electron transport
AC609_13605	COG0713	ATP synthesis coupled electron transport
AC609_13615	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AC609_13620	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AC609_13630	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AC609_13635	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
AC609_13640	COG0649	NAD binding
AC609_13645	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AC609_13650	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AC609_13655	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AC609_13670	COG0149	triose-phosphate isomerase activity
AC609_13675	COG4221	oxidoreductase activity
AC609_13710	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AC609_13715	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AC609_13720	COG0159	tryptophan synthase activity
AC609_13730	COG0133	tryptophan synthase activity
AC609_13740	COG0135	phosphoribosylanthranilate isomerase activity
AC609_13745	COG0101	tRNA pseudouridine synthase activity
AC609_13765	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AC609_13770	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AC609_13775	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AC609_13780	COG2890	protein-(glutamine-N5) methyltransferase activity
AC609_13790	COG0688	phosphatidylethanolamine metabolic process
AC609_13800	COG0433	COG0433 Predicted ATPase
AC609_13820	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AC609_13825	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AC609_13850	COG0717	Belongs to the dCTP deaminase family
AC609_13855	COG0489	protein tyrosine kinase activity
AC609_13890	COG3590	peptidase
AC609_13915	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AC609_13920	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AC609_13925	COG2311	Membrane
AC609_13930	COG1047	Peptidyl-prolyl cis-trans
AC609_13935	COG0791	NLP P60 protein
AC609_13940	COG0791	NLP P60 protein
AC609_13950	COG4106	trans-aconitate 2-methyltransferase activity
AC609_13955	COG1301	dicarboxylic acid transport
AC609_13960	COG1785	Belongs to the alkaline phosphatase family
AC609_13965	COG0037	tRNA processing
AC609_13970	COG1722	exodeoxyribonuclease VII activity
AC609_13975	COG0142	geranyltranstransferase activity
AC609_13980	COG4104	PAAR repeat-containing protein
AC609_13990	COG0312	modulator of DNA gyrase
AC609_13995	COG3028	Belongs to the UPF0307 family
AC609_14000	COG0312	modulator of DNA gyrase
AC609_14010	COG3164	Protein of unknown function
AC609_14015	COG1530	ribonuclease E activity
AC609_14020	COG0424	maF-like protein
AC609_14025	COG2968	Membrane
AC609_14040	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AC609_14055	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AC609_14070	COG0495	leucyl-tRNA aminoacylation
AC609_14080	COG3118	belongs to the thioredoxin family
AC609_14100	COG5487	UPF0391 membrane protein
AC609_14105	COG2155	Conserved Protein
AC609_14110	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AC609_14160	COG1132	(ABC) transporter
AC609_14190	COG0745	RESPONSE REGULATOR receiver
AC609_14195	COG5000	phosphorelay sensor kinase activity
AC609_14195	COG5002	protein histidine kinase activity
AC609_14200	COG0475	glutathione-regulated potassium exporter activity
AC609_14205	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AC609_14210	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AC609_14225	COG3706	GGDEF domain
AC609_14225	COG0745	RESPONSE REGULATOR receiver
AC609_14230	COG1187	pseudouridine synthase activity
AC609_14235	COG5001	Diguanylate cyclase
AC609_14235	COG5002	protein histidine kinase activity
AC609_14245	COG1595	DNA-templated transcription, initiation
AC609_14280	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AC609_14360	COG0667	Aldo Keto reductase
AC609_14365	COG2814	Major facilitator Superfamily
AC609_14370	COG0583	DNA-binding transcription factor activity
AC609_14380	COG2207	Transcriptional regulator
AC609_14390	COG1309	transcriptional regulator
AC609_14395	COG1538	Outer membrane efflux protein
AC609_14400	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AC609_14415	COG0735	belongs to the Fur family
AC609_14420	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AC609_14445	COG4452	Inner membrane protein CreD
AC609_14465	COG0745	RESPONSE REGULATOR receiver
AC609_14470	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AC609_14490	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AC609_14500	COG0643	Histidine kinase
AC609_14500	COG2198	Histidine kinase
AC609_14505	COG0840	transmembrane signaling receptor activity
AC609_14510	COG0835	chemotaxis
AC609_14515	COG2199	diguanylate cyclase activity
AC609_14515	COG2200	EAL domain
AC609_14515	COG2202	Pas domain
AC609_14520	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AC609_14525	COG2201	protein-glutamate methylesterase activity
AC609_14535	COG3590	peptidase
AC609_14550	COG1515	deoxyribonuclease V activity
AC609_14565	COG1741	Belongs to the pirin family
AC609_14580	COG1741	Belongs to the pirin family
AC609_14585	COG1966	Carbon starvation protein
AC609_14590	COG2879	small protein
AC609_14635	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AC609_14640	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AC609_14645	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AC609_14650	COG2080	2 iron, 2 sulfur cluster binding
AC609_14655	COG3321	synthase
AC609_14655	COG0604	alcohol dehydrogenase
AC609_14655	COG1028	Short-chain dehydrogenase reductase Sdr
AC609_14660	COG2203	Gaf domain
AC609_14660	COG4251	negative regulation of phosphorylation
AC609_14660	COG5001	Diguanylate cyclase
AC609_14660	COG3706	GGDEF domain
AC609_14665	COG0629	single-stranded DNA binding
AC609_14670	COG0142	geranyltranstransferase activity
AC609_14680	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AC609_14695	COG0527	aspartate kinase activity
AC609_14700	COG0384	phenazine biosynthesis protein PhzF
AC609_14705	COG0384	phenazine biosynthesis protein PhzF
AC609_14715	COG1764	response to oxidative stress
AC609_14720	COG0540	Belongs to the ATCase OTCase family
AC609_14725	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AC609_14730	COG1678	Uncharacterized ACR, COG1678
AC609_14735	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
AC609_14740	COG0519	Catalyzes the synthesis of GMP from XMP
AC609_14765	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AC609_14780	COG0739	heme binding
AC609_14800	COG0693	protein deglycase activity
AC609_14810	COG1959	2 iron, 2 sulfur cluster binding
AC609_14815	COG0719	Fe-S assembly protein
AC609_14820	COG0396	ATPase activity
AC609_14825	COG0719	Fe-S assembly protein
AC609_14830	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AC609_14835	COG0456	acetyltransferase
AC609_14845	COG4774	siderophore transport
AC609_14850	COG3128	pkhd-type hydroxylase
AC609_14875	COG3328	transposase activity
AC609_14880	COG1477	protein flavinylation
AC609_14885	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AC609_14895	COG1555	photosystem II stabilization
AC609_14915	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AC609_14925	COG0628	permease
AC609_14935	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AC609_14950	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AC609_14970	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AC609_14975	COG0271	Belongs to the BolA IbaG family
AC609_14985	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AC609_14995	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AC609_15000	COG1137	ATPase activity
AC609_15015	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AC609_15020	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
AC609_15025	COG1660	Displays ATPase and GTPase activities
AC609_15035	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AC609_15050	COG2239	Acts as a magnesium transporter
AC609_15060	COG1294	oxidase, subunit
AC609_15125	COG2951	lytic endotransglycosylase activity
AC609_15130	COG4644	lycopene metabolic process
AC609_15190	COG1271	oxidase subunit
AC609_15200	COG1113	amino acid transport
AC609_15210	COG2963	transposase activity
AC609_15215	COG2801	Transposase and inactivated derivatives
AC609_15235	COG2197	response regulator
AC609_15240	COG0531	amino acid
AC609_15300	COG2814	Major facilitator Superfamily
AC609_15305	COG0754	glutathionylspermidine amidase activity
AC609_15330	COG1842	Phage shock protein A
AC609_15340	COG0259	pyridoxamine-phosphate oxidase activity
AC609_15345	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AC609_15350	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AC609_15360	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AC609_15365	COG2814	Major facilitator Superfamily
AC609_15390	COG2205	protein histidine kinase activity
AC609_15390	COG2198	Histidine kinase
AC609_15390	COG0784	Response regulator, receiver
AC609_15395	COG2353	YceI-like domain
AC609_15415	COG1760	l-serine dehydratase
AC609_15425	COG0460	homoserine dehydrogenase
AC609_15425	COG0527	aspartate kinase activity
AC609_15430	COG0626	cystathionine gamma-synthase activity
AC609_15435	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AC609_15440	COG0739	heme binding
AC609_15445	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AC609_15450	COG1272	protein, Hemolysin III
AC609_15455	COG2982	Protein involved in outer membrane biogenesis
AC609_15460	COG0517	IMP dehydrogenase activity
AC609_15460	COG0516	GMP reductase activity
AC609_15465	COG0463	Glycosyl transferase, family 2
AC609_15470	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AC609_15475	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AC609_15485	COG4771	TonB-dependent receptor
AC609_15490	COG1309	transcriptional regulator
AC609_15500	COG1960	acyl-CoA dehydrogenase activity
AC609_15525	COG3328	transposase activity
AC609_15545	COG0509	glycine decarboxylation via glycine cleavage system
AC609_15550	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AC609_15560	COG0330	HflC and HflK could
AC609_15565	COG1742	UPF0060 membrane protein
AC609_15580	COG0494	nUDIX hydrolase
AC609_15590	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AC609_15595	COG0837	glucose binding
AC609_15625	COG1388	LysM domain
AC609_15625	COG3858	chitin binding
AC609_15630	COG3525	Glycosyl hydrolase, family 20, catalytic domain
AC609_15640	COG1472	Belongs to the glycosyl hydrolase 3 family
AC609_15650	COG3537	Alpha-1,2-mannosidase
AC609_15685	COG3142	Participates in the control of copper homeostasis
AC609_15690	COG1446	asparaginase
AC609_15720	COG0840	transmembrane signaling receptor activity
AC609_15740	COG0189	ligase activity
AC609_15750	COG1397	ADP-ribosylglycohydrolase
AC609_15765	COG1199	ATP-dependent helicase activity
AC609_15775	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AC609_15780	COG1215	transferase activity, transferring glycosyl groups
AC609_15790	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AC609_15795	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AC609_15800	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
AC609_15805	COG0535	radical SAM domain protein
AC609_15810	COG0535	radical SAM domain protein
AC609_15825	COG0837	glucose binding
AC609_15835	COG3328	transposase activity
AC609_15845	COG1643	Atp-dependent helicase
AC609_15850	COG0783	Belongs to the Dps family
AC609_15855	COG0514	ATP-dependent DNA helicase (RecQ)
AC609_15910	COG0840	transmembrane signaling receptor activity
AC609_15930	COG3920	Histidine kinase
AC609_15945	COG0602	queuosine metabolic process
AC609_15955	COG2885	chlorophyll binding
AC609_15960	COG0823	Involved in the tonB-independent uptake of proteins
AC609_15970	COG0848	biopolymer transport protein
AC609_15980	COG0824	Thioesterase
AC609_15985	COG2255	four-way junction helicase activity
AC609_15995	COG3158	transport of potassium into the cell
AC609_16000	COG0632	four-way junction helicase activity
AC609_16005	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AC609_16010	COG0217	transcriptional regulatory protein
AC609_16025	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AC609_16040	COG0477	Major facilitator Superfamily
AC609_16060	COG2755	lipolytic protein G-D-S-L family
AC609_16060	COG0657	acetylesterase activity
AC609_16080	COG0488	(ABC) transporter
AC609_16110	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AC609_16110	COG4651	solute:proton antiporter activity
AC609_16135	COG4772	TonB-dependent receptor
AC609_16145	COG4264	IucA IucC family
AC609_16160	COG0019	diaminopimelate decarboxylase activity
AC609_16185	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
AC609_16195	COG1492	cobalamin metabolic process
AC609_16205	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
AC609_16225	COG4206	TonB-dependent receptor
AC609_16235	COG0542	response to heat
AC609_16285	COG1877	trehalose-phosphatase activity
AC609_16290	COG3387	PFAM Glycoside hydrolase 15-related
AC609_16320	COG0840	transmembrane signaling receptor activity
AC609_16325	COG3011	Protein conserved in bacteria
AC609_16340	COG0564	pseudouridine synthase activity
AC609_16345	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AC609_16355	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AC609_16355	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AC609_16370	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AC609_16375	COG0045	succinate-CoA ligase (ADP-forming) activity
AC609_16415	COG3328	transposase activity
AC609_16425	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
AC609_16430	COG0237	dephospho-CoA kinase activity
AC609_16450	COG0745	RESPONSE REGULATOR receiver
AC609_16460	COG0189	ligase activity
AC609_16485	COG2963	transposase activity
AC609_16490	COG2801	Transposase and inactivated derivatives
AC609_16500	COG2003	Belongs to the UPF0758 family
AC609_16520	COG3039	Transposase
AC609_16525	COG3328	transposase activity
AC609_16535	COG3328	transposase activity
AC609_16540	COG1196	nuclear chromosome segregation
AC609_16590	COG1192	Involved in chromosome partitioning
AC609_16660	COG0270	DNA (cytosine-5-)-methyltransferase activity
AC609_16745	COG3328	transposase activity
AC609_16875	COG5001	Diguanylate cyclase
AC609_16970	COG0583	DNA-binding transcription factor activity
AC609_16990	COG0582	viral genome integration into host DNA
AC609_17010	COG2022	thiamine diphosphate biosynthetic process
AC609_17015	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AC609_17020	COG3273	potassium ion transport
AC609_17020	COG0471	metal ion transport
AC609_17045	COG1970	mechanosensitive ion channel activity
AC609_17060	COG1609	Transcriptional regulator
AC609_17070	COG3250	beta-galactosidase activity
AC609_17075	COG4948	Mandelate Racemase Muconate Lactonizing
AC609_17085	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AC609_17095	COG0308	aminopeptidase N
AC609_17100	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AC609_17110	COG2895	sulfate adenylyltransferase (ATP) activity
AC609_17110	COG0529	Catalyzes the synthesis of activated sulfate
AC609_17115	COG0175	sulfate reduction
AC609_17120	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AC609_17125	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AC609_17130	COG0175	sulfate reduction
AC609_17180	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
AC609_17185	COG3588	fructose-bisphosphate aldolase
AC609_17190	COG0469	pyruvate kinase activity
AC609_17200	COG0126	phosphoglycerate kinase activity
AC609_17230	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AC609_17240	COG3047	cAMP biosynthetic process
AC609_17255	COG3453	Protein conserved in bacteria
AC609_17255	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AC609_17260	COG0725	ABC transporter, periplasmic molybdate-binding protein
AC609_17265	COG4149	molybdate abc transporter
AC609_17270	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AC609_17290	COG0642	Histidine kinase
AC609_17295	COG0745	RESPONSE REGULATOR receiver
AC609_17315	COG1022	Amp-dependent synthetase and ligase
AC609_17340	COG1376	ErfK ybiS ycfS ynhG family protein
AC609_17345	COG0739	heme binding
AC609_17365	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AC609_17370	COG1301	dicarboxylic acid transport
AC609_17380	COG2304	oxidoreductase activity
AC609_17400	COG0714	Associated with various cellular activities
AC609_17430	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AC609_17445	COG0254	rRNA binding
AC609_17450	COG1957	nucleoside hydrolase
AC609_17455	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AC609_17465	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AC609_17470	COG1758	RNA polymerase activity
AC609_17480	COG1561	YicC-like family, N-terminal region
AC609_17485	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AC609_17495	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AC609_17500	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AC609_17515	COG0006	proline dipeptidase activity
AC609_17525	COG0006	proline dipeptidase activity
AC609_17530	COG3079	Belongs to the UPF0149 family
AC609_17545	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AC609_17565	COG2912	Transglutaminase-like superfamily
AC609_17570	COG1773	rubredoxin
AC609_17575	COG0352	thiamine-phosphate diphosphorylase activity
AC609_17600	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AC609_17610	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
AC609_17615	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AC609_17645	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AC609_17650	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AC609_17655	COG1028	Short-chain dehydrogenase reductase Sdr
AC609_17665	COG0671	phosphoesterase, PA-phosphatase related
AC609_17670	COG3781	membrane
AC609_17680	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AC609_17685	COG0563	adenylate kinase activity
AC609_17700	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
AC609_17710	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AC609_17730	COG3710	Transcriptional regulator
AC609_17735	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AC609_17745	COG0840	transmembrane signaling receptor activity
AC609_17750	COG0405	Gamma-glutamyltransferase
AC609_17755	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AC609_17775	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AC609_17780	COG0473	3-isopropylmalate dehydrogenase activity
AC609_17785	COG0066	3-isopropylmalate dehydratase activity
AC609_17790	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AC609_17810	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AC609_17815	COG1538	Outer membrane efflux protein
AC609_17820	COG1519	Transferase
AC609_17825	COG1560	Kdo2-lipid A biosynthetic process
AC609_17850	COG0280	phosphate acetyltransferase
AC609_17850	COG0281	malic enzyme
AC609_17855	COG1301	dicarboxylic acid transport
AC609_17880	COG0583	DNA-binding transcription factor activity
AC609_17890	COG0667	Aldo Keto reductase
AC609_17905	COG2197	response regulator
AC609_17910	COG1840	ABC-type Fe3 transport system, periplasmic component
AC609_17915	COG0642	Histidine kinase
AC609_17930	COG2851	Citrate transporter
AC609_17935	COG1028	Short-chain dehydrogenase reductase Sdr
AC609_17940	COG1609	Transcriptional regulator
AC609_17945	COG2211	Major facilitator Superfamily
AC609_17970	COG1162	GTPase activity
AC609_17975	COG0436	Aminotransferase
AC609_17990	COG0726	polysaccharide deacetylase
AC609_17995	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AC609_18010	COG3964	amidohydrolase
AC609_18015	COG0402	S-adenosylhomocysteine deaminase activity
AC609_18040	COG3328	transposase activity
AC609_18050	COG1307	EDD domain protein, DegV family
AC609_18060	COG2963	transposase activity
AC609_18065	COG2801	Transposase and inactivated derivatives
AC609_18070	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
AC609_18075	COG3791	Glutathione-dependent formaldehyde-activating
AC609_18100	COG0745	RESPONSE REGULATOR receiver
AC609_18105	COG2205	protein histidine kinase activity
AC609_18140	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AC609_18150	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AC609_18155	COG1012	belongs to the aldehyde dehydrogenase family
AC609_18160	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
AC609_18185	COG1183	phosphatidylcholine synthase activity
AC609_18195	COG0442	prolyl-tRNA aminoacylation
AC609_18210	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AC609_18215	COG1127	ABC transporter
AC609_18220	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AC609_18220	COG3218	ABC-type transport auxiliary lipoprotein component
AC609_18250	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AC609_18255	COG0662	Cupin 2, conserved barrel domain protein
AC609_18255	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
AC609_18285	COG2086	electron transfer activity
AC609_18300	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AC609_18300	COG0546	phosphoglycolate phosphatase activity
AC609_18305	COG0277	FAD linked oxidase domain protein
AC609_18315	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AC609_18350	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
AC609_18355	COG0438	transferase activity, transferring glycosyl groups
AC609_18395	COG0626	cystathionine gamma-synthase activity
AC609_18425	COG0625	glutathione transferase activity
AC609_18435	COG0513	Belongs to the DEAD box helicase family
AC609_18440	COG0720	synthase
AC609_18450	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AC609_18460	COG1956	GAF domain-containing protein
AC609_18475	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AC609_18480	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AC609_18490	COG4991	sh3 domain protein
AC609_18500	COG0339	signal peptide processing
AC609_18515	COG2132	Multicopper oxidase
AC609_18550	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AC609_18555	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AC609_18560	COG1136	(ABC) transporter
AC609_18565	COG1136	(ABC) transporter
AC609_18565	COG0577	efflux transmembrane transporter activity
AC609_18580	COG2204	response regulator
AC609_18585	COG4191	Histidine kinase
AC609_18590	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AC609_18605	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AC609_18610	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AC609_18615	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AC609_18620	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AC609_18625	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AC609_18630	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AC609_18640	COG0356	it plays a direct role in the translocation of protons across the membrane
AC609_18660	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AC609_18670	COG0508	dehydrogenase complex catalyzes the overall conversion of
AC609_18710	COG2011	ABC-type metal ion transport system permease component
AC609_18715	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AC609_18720	COG0697	spore germination
AC609_18725	COG1666	GTP binding
AC609_18735	COG2198	Histidine kinase
AC609_18735	COG0784	Response regulator, receiver
AC609_18735	COG5002	protein histidine kinase activity
AC609_18760	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AC609_18765	COG1187	pseudouridine synthase activity
AC609_18770	COG2813	Specifically methylates the guanine in position
AC609_18780	COG3039	Transposase
AC609_18785	COG3328	transposase activity
AC609_18800	COG2202	Pas domain
AC609_18800	COG2205	protein histidine kinase activity
AC609_18820	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AC609_18825	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AC609_18830	COG1522	sequence-specific DNA binding
AC609_18880	COG0842	Transport permease protein
AC609_18885	COG1131	(ABC) transporter
AC609_18890	COG0025	NhaP-type Na H and K H
AC609_18895	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
AC609_18900	COG1573	uracil-dna glycosylase
AC609_18910	COG3384	dioxygenase
AC609_18920	COG0583	DNA-binding transcription factor activity
AC609_18930	COG0667	Aldo Keto reductase
AC609_18940	COG3590	peptidase
AC609_18955	COG0531	amino acid
AC609_18970	COG2972	Histidine kinase
AC609_18985	COG3685	Protein conserved in bacteria
AC609_18990	COG3546	catalase activity
AC609_19040	COG1271	oxidase subunit
AC609_19045	COG1294	oxidase, subunit
AC609_19060	COG1028	Short-chain dehydrogenase reductase Sdr
AC609_19080	COG1063	alcohol dehydrogenase
AC609_19090	COG3328	transposase activity
AC609_19155	COG0251	oxidation-reduction process
AC609_19185	COG0659	secondary active sulfate transmembrane transporter activity
AC609_19190	COG0038	chloride channel
AC609_19200	COG0024	Methionine aminopeptidase
AC609_19235	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AC609_19240	COG1490	D-aminoacyl-tRNA deacylase activity
AC609_19245	COG1560	Kdo2-lipid A biosynthetic process
AC609_19295	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AC609_19295	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AC609_19300	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AC609_19305	COG0242	peptide deformylase activity
AC609_19310	COG1652	LysM domain
AC609_19315	COG0758	DNA mediated transformation
AC609_19335	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AC609_19335	COG1754	DNA topoisomerase type I activity
AC609_19340	COG0009	L-threonylcarbamoyladenylate synthase
AC609_19355	COG1028	Short-chain dehydrogenase reductase Sdr
AC609_19365	COG0616	signal peptide processing
AC609_19370	COG0534	Mate efflux family protein
AC609_19390	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AC609_19395	COG0625	glutathione transferase activity
AC609_19415	COG2860	membrane
AC609_19420	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AC609_19425	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AC609_19430	COG2201	protein-glutamate methylesterase activity
AC609_19435	COG2177	Part of the ABC transporter FtsEX involved in
AC609_19440	COG2884	Cell division ATP-binding protein ftsE
AC609_19445	COG0513	Belongs to the DEAD box helicase family
AC609_19450	COG3118	belongs to the thioredoxin family
AC609_19455	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AC609_19465	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
AC609_19490	COG1652	LysM domain
AC609_19495	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AC609_19495	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AC609_19500	COG1473	amidohydrolase
AC609_19505	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AC609_19510	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AC609_19530	COG5383	Protein conserved in bacteria
AC609_19555	COG3328	transposase activity
AC609_19575	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
AC609_19580	COG3023	N-Acetylmuramoyl-L-alanine amidase
AC609_19600	COG0531	amino acid
AC609_19620	COG3328	transposase activity
AC609_19630	COG2133	pyrroloquinoline quinone binding
AC609_19650	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AC609_19655	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AC609_19660	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AC609_19665	COG1610	YqeY-like protein
AC609_19675	COG1295	ribonuclease BN
AC609_19680	COG0358	DNA primase activity
AC609_19695	COG0109	protoheme IX farnesyltransferase activity
AC609_19725	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
AC609_19740	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AC609_19780	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AC609_19785	COG0739	heme binding
AC609_19790	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AC609_19800	COG2223	nitrite transmembrane transporter activity
AC609_19805	COG0708	Exodeoxyribonuclease III
AC609_19810	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AC609_19820	COG1192	Involved in chromosome partitioning
AC609_19825	COG1475	DNA binding
AC609_19840	COG0463	Glycosyl transferase, family 2
AC609_19860	COG0756	dUTP diphosphatase activity
AC609_19865	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AC609_19870	COG2003	Belongs to the UPF0758 family
AC609_19875	COG0018	arginyl-trna synthetase
AC609_19890	COG4221	oxidoreductase activity
AC609_19900	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AC609_19900	COG2755	lipolytic protein G-D-S-L family
AC609_19910	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AC609_19915	COG1166	arginine decarboxylase activity
AC609_19920	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AC609_19945	COG3525	Glycosyl hydrolase, family 20, catalytic domain
AC609_19945	COG3291	Pkd domain containing protein
AC609_19960	COG0606	chelatase, subunit chli
AC609_19975	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AC609_20010	COG1690	Belongs to the RtcB family
AC609_20050	COG1090	epimerase
AC609_20055	COG0745	RESPONSE REGULATOR receiver
AC609_20060	COG0642	Histidine kinase
AC609_20080	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AC609_20105	COG1011	Hydrolase
AC609_20110	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AC609_20125	COG0753	catalase activity
AC609_20145	COG2197	response regulator
AC609_20150	COG4585	Histidine kinase
AC609_20155	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AC609_20160	COG1136	(ABC) transporter
AC609_20185	COG0697	spore germination
AC609_20205	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AC609_20210	COG0180	Tryptophanyl-tRNA synthetase
AC609_20215	COG3237	CsbD-like
AC609_20255	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AC609_20270	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AC609_20275	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
AC609_20275	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
AC609_20285	COG3228	Belongs to the MtfA family
AC609_20300	COG2205	protein histidine kinase activity
AC609_20305	COG0745	RESPONSE REGULATOR receiver
AC609_20315	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AC609_20355	COG3328	transposase activity
AC609_20370	COG1199	ATP-dependent helicase activity
AC609_20385	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AC609_20475	COG4555	ABC transporter
AC609_20485	COG1476	TRANSCRIPTIONal
AC609_20505	COG1230	cation diffusion facilitator family transporter
AC609_20510	COG0633	Ferredoxin
AC609_20510	COG0543	2 iron, 2 sulfur cluster binding
AC609_20515	COG1131	(ABC) transporter
AC609_20520	COG0842	Transport permease protein
AC609_20525	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AC609_20555	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AC609_20575	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AC609_20580	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AC609_20590	COG0045	succinate-CoA ligase (ADP-forming) activity
AC609_20590	COG1042	CoA-binding domain protein
AC609_20590	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AC609_20595	COG2239	Acts as a magnesium transporter
AC609_20620	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AC609_20625	COG3387	PFAM Glycoside hydrolase 15-related
AC609_20640	COG3100	YcgL domain-containing protein
AC609_20645	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AC609_20655	COG0463	Glycosyl transferase, family 2
AC609_20665	COG1028	Short-chain dehydrogenase reductase Sdr
AC609_20705	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AC609_20720	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AC609_20760	COG0408	coproporphyrinogen oxidase activity
AC609_20795	COG0515	serine threonine protein kinase
AC609_20800	COG0631	protein serine/threonine phosphatase activity
AC609_20825	COG0667	Aldo Keto reductase
AC609_20830	COG0583	DNA-binding transcription factor activity
AC609_20845	COG3501	Rhs element vgr protein
AC609_20900	COG0154	amidase activity
AC609_20930	COG3328	transposase activity
AC609_20935	COG3039	Transposase
AC609_21015	COG0210	DNA helicase
AC609_21030	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AC609_21035	COG0583	DNA-binding transcription factor activity
AC609_21040	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AC609_21050	COG2159	amidohydrolase
AC609_21055	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AC609_21060	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AC609_21080	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AC609_21100	COG0357	Ribosomal RNA small subunit methyltransferase G
AC609_21105	COG3540	Alkaline phosphatase
AC609_21115	COG2091	lysine biosynthetic process via aminoadipic acid
AC609_21135	COG0708	Exodeoxyribonuclease III
AC609_21140	COG1846	Transcriptional regulator
AC609_21140	COG1940	carbohydrate kinase activity
AC609_21160	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AC609_21165	COG3162	membrane
AC609_21175	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AC609_21200	COG3507	Belongs to the glycosyl hydrolase 43 family
AC609_21220	COG1028	Short-chain dehydrogenase reductase Sdr
AC609_21225	COG0179	Fumarylacetoacetate (FAA) hydrolase
AC609_21230	COG4948	Mandelate Racemase Muconate Lactonizing
AC609_21235	COG3254	rhamnose metabolic process
AC609_21240	COG0738	Major facilitator superfamily
AC609_21245	COG1414	Transcriptional regulator
AC609_21250	COG2207	Transcriptional regulator
AC609_21250	COG1917	Cupin 2, conserved barrel domain protein
AC609_21260	COG1971	Probably functions as a manganese efflux pump
AC609_21265	COG2205	protein histidine kinase activity
AC609_21275	COG3459	Glycosyltransferase 36 associated
AC609_21280	COG2211	Major facilitator Superfamily
AC609_21285	COG3265	gluconokinase activity
AC609_21290	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AC609_21310	COG2911	Protein conserved in bacteria
AC609_21315	COG0729	surface antigen
AC609_21320	COG4771	TonB-dependent receptor
AC609_21330	COG0457	Tetratricopeptide repeat
AC609_21340	COG0752	glycyl-tRNA synthetase alpha subunit
AC609_21345	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AC609_21355	COG0519	Catalyzes the synthesis of GMP from XMP
AC609_21355	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AC609_21370	COG0805	protein transport
AC609_21375	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AC609_21380	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AC609_21390	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AC609_21420	COG2974	May be involved in recombination
AC609_21425	COG0037	tRNA processing
AC609_21430	COG2115	Belongs to the xylose isomerase family
AC609_21440	COG3661	Belongs to the glycosyl hydrolase 67 family
AC609_21450	COG4948	Mandelate Racemase Muconate Lactonizing
AC609_21460	COG1472	Belongs to the glycosyl hydrolase 3 family
AC609_21465	COG0246	Mannitol dehydrogenase
AC609_21520	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AC609_21545	COG3386	PFAM SMP-30 Gluconolaconase
AC609_21555	COG3250	beta-galactosidase activity
AC609_21560	COG1904	glucuronate isomerase
AC609_21565	COG3693	PFAM glycoside hydrolase, family 10
AC609_21575	COG3693	PFAM glycoside hydrolase, family 10
AC609_21590	COG2211	Major facilitator Superfamily
AC609_21660	COG2937	Belongs to the GPAT DAPAT family
AC609_21695	COG0284	orotidine-5'-phosphate decarboxylase activity
AC609_21700	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
AC609_21705	COG3132	Protein of unknown function, DUF480
AC609_21715	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AC609_21770	COG0210	DNA helicase
AC609_21775	COG1435	thymidine kinase activity
AC609_21785	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
AC609_21805	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AC609_21835	COG3135	benzoate transporter
AC609_21860	COG0676	glucose-6-phosphate 1-epimerase activity
AC609_21870	COG3012	SEC-C Motif Domain Protein
AC609_21935	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AC609_21945	COG4221	oxidoreductase activity
AC609_21950	COG0583	DNA-binding transcription factor activity
AC609_21960	COG0477	Major facilitator Superfamily
AC609_21965	COG1289	transmembrane transporter activity
AC609_21975	COG1566	PFAM secretion protein HlyD family protein
AC609_21990	COG0302	gtp cyclohydrolase
AC609_22010	COG3328	transposase activity
AC609_22020	COG0730	response to heat
AC609_22035	COG3328	transposase activity
AC609_22060	COG0564	pseudouridine synthase activity
AC609_22155	COG4790	Type iii secretion
AC609_22175	COG1157	protein secretion by the type III secretion system
AC609_22185	COG4789	Type iii secretion
AC609_22290	COG3039	Transposase
AC609_22330	COG2963	transposase activity
AC609_22335	COG2801	Transposase and inactivated derivatives
AC609_22375	COG2801	Transposase and inactivated derivatives
AC609_22380	COG2963	transposase activity
AC609_22400	COG0439	Biotin carboxylase
AC609_22430	COG1028	Short-chain dehydrogenase reductase Sdr
AC609_22470	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AC609_22475	COG1074	ATP-dependent DNA helicase activity
AC609_22480	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AC609_22515	COG1127	ABC transporter
AC609_22520	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AC609_22525	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AC609_22540	COG2853	Lipoprotein
AC609_22555	COG0386	Belongs to the glutathione peroxidase family
AC609_22565	COG1322	Protein conserved in bacteria
AC609_22575	COG0583	DNA-binding transcription factor activity
AC609_22600	COG0531	amino acid
AC609_22605	COG3537	Alpha-1,2-mannosidase
AC609_22615	COG2199	diguanylate cyclase activity
AC609_22615	COG2203	Gaf domain
AC609_22620	COG3835	regulator
AC609_22625	COG1929	Belongs to the glycerate kinase type-1 family
AC609_22645	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AC609_22650	COG0861	Integral membrane protein TerC family
AC609_22660	COG0584	glycerophosphoryl diester phosphodiesterase
AC609_22675	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AC609_22680	COG0726	polysaccharide deacetylase
AC609_22685	COG0706	membrane insertase activity
AC609_22690	COG0594	ribonuclease P activity
AC609_22695	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AC609_22810	COG3328	transposase activity
AC609_22860	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AC609_22865	COG4691	Plasmid stability protein
AC609_22870	COG1487	ribonuclease activity
AC609_22885	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AC609_22935	COG3846	protein secretion by the type IV secretion system
AC609_22945	COG3451	type IV secretory pathway VirB4
AC609_22955	COG4962	Type ii secretion system protein e
AC609_23105	COG3039	Transposase
AC609_23130	COG3328	transposase activity
AC609_23175	COG3328	transposase activity
AC609_23230	COG1487	ribonuclease activity
AC609_23235	COG4691	Plasmid stability protein
AC609_23240	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AC609_23345	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)