locus-tag	class	description
AC610_00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AC610_00020	COG0187	DNA topoisomerase II activity
AC610_00030	COG0501	Belongs to the peptidase M48B family
AC610_00080	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AC610_00135	COG0793	Belongs to the peptidase S41A family
AC610_00140	COG4942	peptidase
AC610_00150	COG2234	aminopeptidase activity
AC610_00160	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
AC610_00165	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
AC610_00175	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
AC610_00180	COG1064	alcohol dehydrogenase
AC610_00190	COG0493	'glutamate synthase
AC610_00195	COG0067	glutamate synthase
AC610_00195	COG0069	glutamate synthase activity
AC610_00195	COG0070	glutamate synthase
AC610_00280	COG1205	dead DEAH box helicase
AC610_00280	COG1111	helicase
AC610_00285	COG1272	protein, Hemolysin III
AC610_00295	COG0300	oxidoreductase activity
AC610_00300	COG1028	Short-chain dehydrogenase reductase Sdr
AC610_00330	COG2249	NAD(P)H dehydrogenase (quinone) activity
AC610_00335	COG2963	transposase activity
AC610_00340	COG3039	Transposase
AC610_00350	COG3039	Transposase
AC610_00365	COG3237	CsbD-like
AC610_00415	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AC610_00420	COG0477	Major facilitator Superfamily
AC610_00460	COG0714	Associated with various cellular activities
AC610_00500	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AC610_00510	COG4772	TonB-dependent receptor
AC610_00535	COG1304	FMN binding
AC610_00540	COG1755	Isoprenylcysteine carboxyl methyltransferase
AC610_00545	COG4585	Histidine kinase
AC610_00550	COG2197	response regulator
AC610_00575	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AC610_00580	COG3039	Transposase
AC610_00600	COG0366	Alpha amylase catalytic
AC610_00605	COG0366	Alpha amylase catalytic
AC610_00610	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AC610_00630	COG2755	lipolytic protein G-D-S-L family
AC610_00630	COG0657	acetylesterase activity
AC610_00640	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AC610_00655	COG3507	Belongs to the glycosyl hydrolase 43 family
AC610_00660	COG1609	Transcriptional regulator
AC610_00665	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
AC610_00670	COG1028	Short-chain dehydrogenase reductase Sdr
AC610_00680	COG2755	lipolytic protein G-D-S-L family
AC610_00690	COG3186	Phenylalanine-4-hydroxylase
AC610_00695	COG1522	sequence-specific DNA binding
AC610_00705	COG1752	Esterase of the alpha-beta hydrolase superfamily
AC610_00715	COG1119	ATPase activity
AC610_00730	COG1125	glycine betaine transport
AC610_00730	COG0517	IMP dehydrogenase activity
AC610_00745	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AC610_00775	COG0489	protein tyrosine kinase activity
AC610_00780	COG2062	phosphohistidine phosphatase, SixA
AC610_00790	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AC610_00830	COG1968	undecaprenyl-diphosphatase activity
AC610_00835	COG0174	glutamine synthetase
AC610_00840	COG0347	Belongs to the P(II) protein family
AC610_00845	COG0004	ammonium transporteR
AC610_00850	COG3852	Histidine kinase
AC610_00855	COG2204	response regulator
AC610_00860	COG2032	superoxide dismutase activity
AC610_00865	COG2032	superoxide dismutase activity
AC610_00880	COG0183	Belongs to the thiolase family
AC610_00915	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AC610_00920	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
AC610_00925	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AC610_00955	COG2205	protein histidine kinase activity
AC610_00980	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AC610_00995	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AC610_01000	COG3177	Filamentation induced by cAMP protein fic
AC610_01005	COG0596	Alpha beta hydrolase
AC610_01015	COG0318	PFAM AMP-dependent synthetase and ligase
AC610_01020	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AC610_01040	COG1181	Belongs to the D-alanine--D-alanine ligase family
AC610_01050	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AC610_01060	COG0564	pseudouridine synthase activity
AC610_01080	COG1446	asparaginase
AC610_01085	COG0339	signal peptide processing
AC610_01115	COG0475	glutathione-regulated potassium exporter activity
AC610_01125	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AC610_01130	COG2224	Isocitrate lyase
AC610_01135	COG3706	GGDEF domain
AC610_01150	COG3039	Transposase
AC610_01170	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AC610_01175	COG1960	acyl-CoA dehydrogenase activity
AC610_01245	COG0697	spore germination
AC610_01255	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AC610_01260	COG1846	Transcriptional regulator
AC610_01265	COG1764	response to oxidative stress
AC610_01285	COG2130	NADP-dependent
AC610_01300	COG1187	pseudouridine synthase activity
AC610_01310	COG1643	Atp-dependent helicase
AC610_01315	COG4807	Protein conserved in bacteria
AC610_01320	COG2351	hydroxyisourate hydrolase activity
AC610_01325	COG2072	flavoprotein involved in K transport
AC610_01345	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AC610_01355	COG0583	DNA-binding transcription factor activity
AC610_01390	COG2252	PERMEase
AC610_01415	COG0084	hydrolase, TatD family'
AC610_01430	COG0583	DNA-binding transcription factor activity
AC610_01435	COG2814	Major facilitator Superfamily
AC610_01450	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AC610_01455	COG1902	pentaerythritol trinitrate reductase activity
AC610_01475	COG0745	RESPONSE REGULATOR receiver
AC610_01480	COG2205	protein histidine kinase activity
AC610_01485	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AC610_01510	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AC610_01515	COG0583	DNA-binding transcription factor activity
AC610_01530	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AC610_01555	COG0702	epimerase
AC610_01560	COG1733	regulation of RNA biosynthetic process
AC610_01580	COG3328	transposase activity
AC610_01615	COG2963	transposase activity
AC610_01620	COG2801	Transposase and inactivated derivatives
AC610_01630	COG0129	dihydroxy-acid dehydratase activity
AC610_01650	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AC610_01705	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AC610_01710	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AC610_01735	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AC610_01750	COG3485	protocatechuate 3,4-dioxygenase
AC610_01755	COG3485	protocatechuate 3,4-dioxygenase
AC610_01765	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AC610_01770	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AC610_01780	COG1414	Transcriptional regulator
AC610_01800	COG0445	tRNA wobble uridine modification
AC610_01840	COG2267	carboxylic ester hydrolase activity
AC610_01850	COG0156	8-amino-7-oxononanoate synthase activity
AC610_01855	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AC610_01860	COG1040	competence protein
AC610_01865	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AC610_01885	COG3039	Transposase
AC610_01950	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AC610_02020	COG3264	Mechanosensitive ion channel
AC610_02020	COG1511	domain protein
AC610_02025	COG1368	sulfuric ester hydrolase activity
AC610_02030	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AC610_02035	COG2354	Protein conserved in bacteria
AC610_02040	COG3706	GGDEF domain
AC610_02040	COG0745	RESPONSE REGULATOR receiver
AC610_02045	COG0297	glycogen (starch) synthase activity
AC610_02050	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AC610_02055	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AC610_02080	COG0702	epimerase
AC610_02105	COG3328	transposase activity
AC610_02110	COG2963	transposase activity
AC610_02115	COG3039	Transposase
AC610_02120	COG1028	Short-chain dehydrogenase reductase Sdr
AC610_02155	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AC610_02160	COG1028	Short-chain dehydrogenase reductase Sdr
AC610_02170	COG0513	Belongs to the DEAD box helicase family
AC610_02175	COG0508	dehydrogenase complex catalyzes the overall conversion of
AC610_02190	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AC610_02200	COG3483	tryptophan 2,3-dioxygenase activity
AC610_02205	COG3104	oligopeptide transport
AC610_02230	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
AC610_02245	COG1320	monovalent cation:proton antiporter activity
AC610_02250	COG2212	antiporter activity
AC610_02260	COG0651	ATP synthesis coupled electron transport
AC610_02265	COG1006	Multisubunit Na H antiporter MnhC subunit
AC610_02270	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AC610_02270	COG2111	Na H antiporter
AC610_02290	COG3179	chitinase
AC610_02310	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AC610_02315	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AC610_02335	COG1597	lipid kinase activity
AC610_02360	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AC610_02365	COG0134	indole-3-glycerol-phosphate synthase activity
AC610_02375	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AC610_02380	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
AC610_02390	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
AC610_02395	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AC610_02400	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AC610_02415	COG1051	belongs to the nudix hydrolase family
AC610_02455	COG0316	Belongs to the HesB IscA family
AC610_02470	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
AC610_02485	COG2814	Major facilitator Superfamily
AC610_02495	COG2814	Major facilitator Superfamily
AC610_02500	COG1289	transmembrane transporter activity
AC610_02510	COG0151	Belongs to the GarS family
AC610_02520	COG0138	bifunctional purine biosynthesis protein purh
AC610_02525	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AC610_02530	COG2267	carboxylic ester hydrolase activity
AC610_02535	COG2453	phosphatase
AC610_02535	COG0671	phosphoesterase, PA-phosphatase related
AC610_02560	COG4589	Belongs to the CDS family
AC610_02565	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
AC610_02590	COG2264	protein methyltransferase activity
AC610_02605	COG0439	Biotin carboxylase
AC610_02615	COG0511	ligase activity, forming carbon-carbon bonds
AC610_02620	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AC610_02635	COG1324	tolerance protein
AC610_02645	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AC610_02650	COG0459	protein refolding
AC610_02665	COG3550	peptidyl-serine autophosphorylation
AC610_02670	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AC610_02690	COG3386	PFAM SMP-30 Gluconolaconase
AC610_02700	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AC610_02705	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AC610_02720	COG3039	Transposase
AC610_02735	COG0778	Nitroreductase
AC610_02740	COG2353	YceI-like domain
AC610_02775	COG3052	prosthetic group binding
AC610_02795	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
AC610_02800	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AC610_02810	COG1802	Transcriptional regulator
AC610_02860	COG3328	transposase activity
AC610_02870	COG4221	oxidoreductase activity
AC610_02895	COG4221	oxidoreductase activity
AC610_02905	COG0435	Glutathione S-transferase
AC610_02955	COG3706	GGDEF domain
AC610_02960	COG1959	2 iron, 2 sulfur cluster binding
AC610_02985	COG0697	spore germination
AC610_02990	COG4305	rare lipoprotein A
AC610_03000	COG5297	Belongs to the glycosyl hydrolase family 6
AC610_03015	COG1113	amino acid transport
AC610_03025	COG0598	Magnesium transport protein CorA
AC610_03035	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
AC610_03075	COG2205	protein histidine kinase activity
AC610_03075	COG0784	Response regulator, receiver
AC610_03090	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
AC610_03090	COG5297	Belongs to the glycosyl hydrolase family 6
AC610_03120	COG2943	transferase activity, transferring hexosyl groups
AC610_03130	COG3275	phosphorelay sensor kinase activity
AC610_03140	COG0181	hydroxymethylbilane synthase activity
AC610_03175	COG1505	serine-type exopeptidase activity
AC610_03195	COG2832	Protein of unknown function (DUF454)
AC610_03205	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AC610_03215	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AC610_03220	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AC610_03225	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AC610_03250	COG2226	methyltransferase
AC610_03255	COG3300	MHYT domain
AC610_03255	COG5001	Diguanylate cyclase
AC610_03260	COG0308	aminopeptidase N
AC610_03310	COG3284	Transcriptional regulator
AC610_03330	COG1077	Cell shape determining protein MreB Mrl
AC610_03335	COG1792	Involved in formation and maintenance of cell shape
AC610_03350	COG0772	Belongs to the SEDS family
AC610_03360	COG3039	Transposase
AC610_03385	COG2951	lytic endotransglycosylase activity
AC610_03390	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AC610_03395	COG1686	Belongs to the peptidase S11 family
AC610_03405	COG2921	Belongs to the UPF0250 family
AC610_03410	COG0321	lipoyl(octanoyl) transferase activity
AC610_03415	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AC610_03440	COG1056	cytidyltransferase-related domain
AC610_03440	COG1051	belongs to the nudix hydrolase family
AC610_03475	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
AC610_03480	COG0673	inositol 2-dehydrogenase activity
AC610_03485	COG2823	Periplasmic or secreted lipoprotein
AC610_03490	COG4251	negative regulation of phosphorylation
AC610_03495	COG0784	Response regulator, receiver
AC610_03500	COG4191	Histidine kinase
AC610_03505	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AC610_03560	COG1459	type II secretion system
AC610_03615	COG1609	Transcriptional regulator
AC610_03620	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AC610_03625	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AC610_03635	COG0617	tRNA 3'-terminal CCA addition
AC610_03650	COG0525	valine-tRNA ligase activity
AC610_03665	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AC610_03675	COG0795	lipopolysaccharide-transporting ATPase activity
AC610_03690	COG4974	Belongs to the 'phage' integrase family
AC610_03695	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AC610_03700	COG0047	phosphoribosylformylglycinamidine synthase activity
AC610_03700	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AC610_03710	COG5295	Hep Hag repeat protein
AC610_03715	COG1404	Belongs to the peptidase S8 family
AC610_03720	COG5295	Hep Hag repeat protein
AC610_03725	COG1404	Belongs to the peptidase S8 family
AC610_03730	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AC610_03735	COG1459	type II secretion system
AC610_03740	COG2165	general secretion pathway protein
AC610_03745	COG4970	Tfp pilus assembly protein FimT
AC610_03750	COG2165	general secretion pathway protein
AC610_03755	COG4795	General secretion pathway protein
AC610_03760	COG3156	type II secretion system protein K
AC610_03765	COG3166	PFAM Fimbrial assembly family protein
AC610_03780	COG1450	Type ii and iii secretion system protein
AC610_03790	COG2188	Transcriptional regulator
AC610_03850	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AC610_03865	COG1215	transferase activity, transferring glycosyl groups
AC610_03870	COG1215	transferase activity, transferring glycosyl groups
AC610_03875	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
AC610_03905	COG0242	peptide deformylase activity
AC610_03910	COG0488	(ABC) transporter
AC610_03920	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AC610_03925	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AC610_03935	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AC610_03935	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AC610_03945	COG3328	transposase activity
AC610_03965	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AC610_03970	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AC610_03975	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AC610_03990	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
AC610_03995	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
AC610_04005	COG2205	protein histidine kinase activity
AC610_04010	COG0745	RESPONSE REGULATOR receiver
AC610_04020	COG0277	FAD linked oxidase domain protein
AC610_04025	COG1988	membrane-bound metal-dependent
AC610_04030	COG0792	nuclease activity
AC610_04055	COG2001	Belongs to the MraZ family
AC610_04065	COG3116	cell division
AC610_04075	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AC610_04080	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AC610_04085	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AC610_04095	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AC610_04100	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AC610_04105	COG1181	Belongs to the D-alanine--D-alanine ligase family
AC610_04110	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AC610_04125	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
AC610_04135	COG0739	heme binding
AC610_04140	COG0653	protein targeting
AC610_04145	COG0494	nUDIX hydrolase
AC610_04155	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AC610_04165	COG0604	alcohol dehydrogenase
AC610_04165	COG1028	Short-chain dehydrogenase reductase Sdr
AC610_04165	COG3321	synthase
AC610_04185	COG0366	Alpha amylase catalytic
AC610_04220	COG2226	methyltransferase
AC610_04225	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AC610_04235	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AC610_04275	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AC610_04285	COG4106	trans-aconitate 2-methyltransferase activity
AC610_04290	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AC610_04300	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AC610_04305	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AC610_04310	COG0667	Aldo Keto reductase
AC610_04320	COG4771	TonB-dependent receptor
AC610_04340	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AC610_04345	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AC610_04355	COG2175	clavaminate synthase activity
AC610_04365	COG4181	ATPase activity
AC610_04380	COG0642	Histidine kinase
AC610_04390	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AC610_04400	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
AC610_04410	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AC610_04415	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AC610_04430	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AC610_04435	COG2967	ApaG domain
AC610_04445	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AC610_04450	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AC610_04455	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AC610_04465	COG0123	including yeast histone deacetylase and acetoin utilization protein
AC610_04470	COG2096	Adenosyltransferase
AC610_04480	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AC610_04485	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AC610_04515	COG3384	dioxygenase
AC610_04520	COG0583	DNA-binding transcription factor activity
AC610_04525	COG0318	PFAM AMP-dependent synthetase and ligase
AC610_04535	COG1024	Enoyl-CoA hydratase
AC610_04555	COG3386	PFAM SMP-30 Gluconolaconase
AC610_04565	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
AC610_04590	COG0697	spore germination
AC610_04600	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AC610_04615	COG3706	GGDEF domain
AC610_04615	COG0745	RESPONSE REGULATOR receiver
AC610_04625	COG2197	response regulator
AC610_04635	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AC610_04645	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AC610_04650	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AC610_04655	COG0583	DNA-binding transcription factor activity
AC610_04660	COG3634	alkyl hydroperoxide reductase activity
AC610_04670	COG2890	protein-(glutamine-N5) methyltransferase activity
AC610_04690	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AC610_04690	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AC610_04745	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AC610_04750	COG1404	Belongs to the peptidase S8 family
AC610_04755	COG1404	Belongs to the peptidase S8 family
AC610_04760	COG1404	Belongs to the peptidase S8 family
AC610_04765	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AC610_04790	COG1295	ribonuclease BN
AC610_04795	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AC610_04800	COG1254	Belongs to the acylphosphatase family
AC610_04815	COG0521	Mo-molybdopterin cofactor biosynthetic process
AC610_04825	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AC610_04830	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AC610_04840	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
AC610_04845	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AC610_04855	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AC610_04860	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AC610_04865	COG0193	aminoacyl-tRNA hydrolase activity
AC610_04870	COG0012	GTP binding
AC610_04890	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AC610_04900	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AC610_04905	COG0250	Participates in transcription elongation, termination and antitermination
AC610_04910	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AC610_04915	COG0081	regulation of translation
AC610_04920	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AC610_04930	COG0085	RNA polymerase activity
AC610_04935	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AC610_04940	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AC610_04945	COG0049	tRNA binding
AC610_04950	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AC610_04955	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AC610_04965	COG3328	transposase activity
AC610_04970	COG0051	transcription antitermination factor activity, RNA binding
AC610_04975	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AC610_04980	COG0088	Forms part of the polypeptide exit tunnel
AC610_04985	COG0089	rRNA binding
AC610_04990	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AC610_04995	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AC610_05000	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AC610_05005	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AC610_05010	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AC610_05015	COG0255	Belongs to the universal ribosomal protein uL29 family
AC610_05020	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AC610_05025	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AC610_05030	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AC610_05035	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AC610_05040	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AC610_05045	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AC610_05050	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AC610_05055	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AC610_05060	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AC610_05065	COG1841	ribosomal large subunit assembly
AC610_05070	COG0200	Binds to the 23S rRNA
AC610_05075	COG0201	protein transport
AC610_05080	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AC610_05085	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AC610_05090	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AC610_05095	COG0202	RNA polymerase activity
AC610_05100	COG0203	ribosomal protein L17
AC610_05105	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AC610_05125	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
AC610_05135	COG0154	amidase activity
AC610_05150	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AC610_05155	COG0039	L-malate dehydrogenase activity
AC610_05160	COG0625	glutathione transferase activity
AC610_05170	COG0446	pyridine nucleotide-disulphide oxidoreductase
AC610_05170	COG1902	pentaerythritol trinitrate reductase activity
AC610_05175	COG0604	alcohol dehydrogenase
AC610_05180	COG3328	transposase activity
AC610_05185	COG3039	Transposase
AC610_05190	COG2885	chlorophyll binding
AC610_05210	COG0156	8-amino-7-oxononanoate synthase activity
AC610_05215	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AC610_05220	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AC610_05225	COG4208	sulfate ABC transporter
AC610_05230	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AC610_05240	COG3328	transposase activity
AC610_05245	COG1063	alcohol dehydrogenase
AC610_05265	COG0406	alpha-ribazole phosphatase activity
AC610_05275	COG0285	dihydrofolate synthase activity
AC610_05295	COG2833	Protein of unknown function (DUF455)
AC610_05310	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AC610_05315	COG0671	phosphoesterase, PA-phosphatase related
AC610_05320	COG0438	transferase activity, transferring glycosyl groups
AC610_05330	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AC610_05345	COG4783	chaperone-mediated protein folding
AC610_05360	COG0473	3-isopropylmalate dehydrogenase activity
AC610_05395	COG3328	transposase activity
AC610_05410	COG0544	peptidyl-prolyl cis-trans isomerase activity
AC610_05415	COG0740	serine-type endopeptidase activity
AC610_05420	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AC610_05450	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AC610_05460	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AC610_05470	COG0328	RNA-DNA hybrid ribonuclease activity
AC610_05475	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AC610_05480	COG0631	protein serine/threonine phosphatase activity
AC610_05495	COG0859	PFAM glycosyl transferase family 9
AC610_05500	COG3642	lipopolysaccharide core region biosynthetic process
AC610_05505	COG1234	tRNA 3'-trailer cleavage
AC610_05510	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AC610_05520	COG0315	cyclic pyranopterin monophosphate synthase activity
AC610_05525	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AC610_05530	COG0314	molybdopterin synthase activity
AC610_05545	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AC610_05550	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AC610_05555	COG0537	adenosine 5'-monophosphoramidase activity
AC610_05575	COG0714	Associated with various cellular activities
AC610_05585	COG0424	maF-like protein
AC610_05590	COG1399	metal-binding, possibly nucleic acid-binding protein
AC610_05595	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AC610_05600	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AC610_05615	COG1028	Short-chain dehydrogenase reductase Sdr
AC610_05620	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AC610_05630	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AC610_05635	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AC610_05670	COG3829	transcription factor binding
AC610_05710	COG2373	Large extracellular alpha-helical protein
AC610_05730	COG3852	Histidine kinase
AC610_05735	COG4953	penicillin-binding protein 1C
AC610_05745	COG0678	peroxiredoxin activity
AC610_05765	COG0330	HflC and HflK could
AC610_05770	COG0330	HflC and HflK could
AC610_05780	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AC610_05785	COG0308	aminopeptidase N
AC610_05795	COG1028	Short-chain dehydrogenase reductase Sdr
AC610_05800	COG1309	transcriptional regulator
AC610_05850	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AC610_05860	COG3387	PFAM Glycoside hydrolase 15-related
AC610_05865	COG1028	Short-chain dehydrogenase reductase Sdr
AC610_05870	COG3537	Alpha-1,2-mannosidase
AC610_05890	COG0492	ferredoxin-NADP+ reductase activity
AC610_05925	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AC610_05930	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AC610_05935	COG2080	2 iron, 2 sulfur cluster binding
AC610_05970	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AC610_05990	COG0587	DNA-directed DNA polymerase activity
AC610_06005	COG1297	OPT oligopeptide transporter protein
AC610_06030	COG1506	peptidase
AC610_06030	COG0823	Involved in the tonB-independent uptake of proteins
AC610_06050	COG2207	Transcriptional regulator
AC610_06050	COG1917	Cupin 2, conserved barrel domain protein
AC610_06065	COG3328	transposase activity
AC610_06075	COG0753	catalase activity
AC610_06080	COG0656	L-ascorbic acid biosynthetic process
AC610_06090	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AC610_06090	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AC610_06115	COG2814	Major facilitator Superfamily
AC610_06125	COG2801	Transposase and inactivated derivatives
AC610_06155	COG2194	sulfuric ester hydrolase activity
AC610_06170	COG0745	RESPONSE REGULATOR receiver
AC610_06175	COG0642	Histidine kinase
AC610_06185	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
AC610_06190	COG2894	cell division
AC610_06195	COG0850	regulation of cytokinetic process
AC610_06205	COG4585	Histidine kinase
AC610_06210	COG2197	response regulator
AC610_06230	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AC610_06255	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AC610_06265	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
AC610_06280	COG1595	DNA-templated transcription, initiation
AC610_06290	COG1946	Acyl-CoA thioesterase
AC610_06305	COG0824	Thioesterase
AC610_06310	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AC610_06315	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AC610_06320	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AC610_06325	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AC610_06330	COG0268	Binds directly to 16S ribosomal RNA
AC610_06340	COG0196	riboflavin kinase activity
AC610_06345	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AC610_06350	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AC610_06355	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AC610_06460	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
AC610_06460	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AC610_06500	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AC610_06505	COG1845	cytochrome c oxidase, subunit III
AC610_06510	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AC610_06525	COG3152	Membrane
AC610_06535	COG2207	Transcriptional regulator
AC610_06540	COG0326	Molecular chaperone. Has ATPase activity
AC610_06550	COG1366	Belongs to the anti-sigma-factor antagonist family
AC610_06555	COG1366	Belongs to the anti-sigma-factor antagonist family
AC610_06585	COG4771	TonB-dependent receptor
AC610_06595	COG5507	3-demethylubiquinone-9 3-methyltransferase
AC610_06600	COG2205	protein histidine kinase activity
AC610_06610	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AC610_06615	COG3850	Histidine kinase
AC610_06615	COG4999	Histidine kinase
AC610_06615	COG3437	response regulator, receiver
AC610_06615	COG2205	protein histidine kinase activity
AC610_06620	COG0784	Response regulator, receiver
AC610_06620	COG4191	Histidine kinase
AC610_06650	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AC610_06665	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AC610_06670	COG0228	four-way junction DNA binding
AC610_06675	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AC610_06680	COG0336	Belongs to the RNA methyltransferase TrmD family
AC610_06685	COG0335	large ribosomal subunit rRNA binding
AC610_06690	COG0534	Mate efflux family protein
AC610_06715	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
AC610_06725	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AC610_06730	COG2801	Transposase and inactivated derivatives
AC610_06735	COG2963	transposase activity
AC610_06740	COG2963	transposase activity
AC610_06745	COG2801	Transposase and inactivated derivatives
AC610_06750	COG2801	Transposase and inactivated derivatives
AC610_06755	COG2963	transposase activity
AC610_06775	COG3250	beta-galactosidase activity
AC610_06780	COG3867	Arabinogalactan endo-beta-1,4-galactanase
AC610_06800	COG1960	acyl-CoA dehydrogenase activity
AC610_06830	COG0457	Tetratricopeptide repeat
AC610_06840	COG0457	Tetratricopeptide repeat
AC610_06850	COG1250	3-hydroxyacyl-CoA dehydrogenase
AC610_06850	COG1024	Enoyl-CoA hydratase
AC610_06865	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AC610_06870	COG0481	GTPase activity
AC610_06885	COG0571	ribonuclease III activity
AC610_06890	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AC610_06895	COG1381	Involved in DNA repair and RecF pathway recombination
AC610_06905	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AC610_06915	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AC610_06920	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
AC610_06925	COG3046	protein related to deoxyribodipyrimidine photolyase
AC610_06930	COG1472	Belongs to the glycosyl hydrolase 3 family
AC610_06940	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AC610_06945	COG1278	Cold shock
AC610_06950	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AC610_06960	COG1201	RNA secondary structure unwinding
AC610_06965	COG1793	dna ligase
AC610_06975	COG1793	dna ligase
AC610_06975	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AC610_06990	COG0745	RESPONSE REGULATOR receiver
AC610_06990	COG3706	GGDEF domain
AC610_07005	COG0183	Belongs to the thiolase family
AC610_07025	COG1451	nucleotide metabolic process
AC610_07030	COG5487	UPF0391 membrane protein
AC610_07040	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AC610_07060	COG1077	Cell shape determining protein MreB Mrl
AC610_07065	COG1047	Peptidyl-prolyl cis-trans
AC610_07075	COG2824	Alkylphosphonate utilization operon protein PhnA
AC610_07085	COG1902	pentaerythritol trinitrate reductase activity
AC610_07090	COG2814	Major facilitator Superfamily
AC610_07125	COG0392	lysyltransferase activity
AC610_07125	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
AC610_07135	COG0251	oxidation-reduction process
AC610_07140	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AC610_07155	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AC610_07180	COG1595	DNA-templated transcription, initiation
AC610_07200	COG2878	Part of a membrane complex involved in electron transport
AC610_07210	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AC610_07210	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AC610_07230	COG0346	lactoylglutathione lyase activity
AC610_07245	COG0833	amino acid
AC610_07250	COG2040	homocysteine
AC610_07260	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AC610_07280	COG1695	Transcriptional regulator
AC610_07315	COG0825	malonyl-CoA metabolic process
AC610_07330	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AC610_07335	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AC610_07340	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AC610_07345	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AC610_07360	COG0750	zinc metalloprotease
AC610_07365	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AC610_07370	COG0575	Belongs to the CDS family
AC610_07375	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AC610_07380	COG0233	cytoplasmic translational termination
AC610_07385	COG0528	UMP kinase activity
AC610_07390	COG3706	GGDEF domain
AC610_07390	COG0745	RESPONSE REGULATOR receiver
AC610_07395	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AC610_07400	COG0052	Belongs to the universal ribosomal protein uS2 family
AC610_07435	COG0024	Methionine aminopeptidase
AC610_07440	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AC610_07450	COG1393	Belongs to the ArsC family
AC610_07455	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AC610_07460	COG0367	asparagine synthase
AC610_07475	COG4774	siderophore transport
AC610_07520	COG2963	transposase activity
AC610_07525	COG2801	Transposase and inactivated derivatives
AC610_07530	COG3328	transposase activity
AC610_07565	COG1566	PFAM secretion protein HlyD family protein
AC610_07570	COG2814	Major facilitator Superfamily
AC610_07630	COG0339	signal peptide processing
AC610_07635	COG0386	Belongs to the glutathione peroxidase family
AC610_07695	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AC610_07700	COG0084	hydrolase, TatD family'
AC610_07715	COG1960	acyl-CoA dehydrogenase activity
AC610_07730	COG0367	asparagine synthase
AC610_07740	COG0305	Participates in initiation and elongation during chromosome replication
AC610_07745	COG0415	Belongs to the DNA photolyase family
AC610_07755	COG0583	DNA-binding transcription factor activity
AC610_07790	COG3706	GGDEF domain
AC610_07800	COG3706	GGDEF domain
AC610_07820	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AC610_07835	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AC610_07845	COG0497	DNA recombination
AC610_07850	COG1420	regulation of RNA biosynthetic process
AC610_07855	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AC610_07860	COG0443	Heat shock 70 kDa protein
AC610_07865	COG0484	heat shock protein binding
AC610_07870	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
AC610_07900	COG0583	DNA-binding transcription factor activity
AC610_07905	COG1132	(ABC) transporter
AC610_07940	COG2850	peptidyl-arginine hydroxylation
AC610_07960	COG1253	flavin adenine dinucleotide binding
AC610_07990	COG1131	(ABC) transporter
AC610_07995	COG1725	Transcriptional regulator
AC610_08000	COG0386	Belongs to the glutathione peroxidase family
AC610_08010	COG2900	Belongs to the SlyX family
AC610_08035	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AC610_08045	COG0646	methionine synthase
AC610_08045	COG1410	methionine synthase
AC610_08060	COG1960	acyl-CoA dehydrogenase activity
AC610_08075	COG0557	exoribonuclease II activity
AC610_08085	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AC610_08100	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AC610_08110	COG0704	Plays a role in the regulation of phosphate uptake
AC610_08115	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AC610_08120	COG0581	inorganic phosphate transmembrane transporter activity
AC610_08125	COG0573	inorganic phosphate transmembrane transporter activity
AC610_08130	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AC610_08155	COG0659	secondary active sulfate transmembrane transporter activity
AC610_08160	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AC610_08170	COG1024	Enoyl-CoA hydratase
AC610_08180	COG0494	nUDIX hydrolase
AC610_08225	COG0116	Belongs to the methyltransferase superfamily
AC610_08225	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AC610_08230	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AC610_08250	COG2925	Exonuclease
AC610_08255	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AC610_08260	COG3844	kynureninase activity
AC610_08270	COG0662	Cupin 2, conserved barrel domain protein
AC610_08275	COG0288	reversible hydration of carbon dioxide
AC610_08350	COG0017	Asparaginyl-tRNA synthetase
AC610_08355	COG0316	Belongs to the HesB IscA family
AC610_08360	COG0360	Binds together with S18 to 16S ribosomal RNA
AC610_08365	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AC610_08370	COG0359	binds to the 23S rRNA
AC610_08380	COG3115	cell septum assembly
AC610_08390	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AC610_08395	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AC610_08400	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
AC610_08410	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
AC610_08420	COG4993	Dehydrogenase
AC610_08430	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
AC610_08445	COG2986	histidine ammonia-lyase
AC610_08450	COG1228	amidohydrolase
AC610_08490	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
AC610_08495	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AC610_08500	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AC610_08505	COG0077	Prephenate dehydratase
AC610_08505	COG1605	Chorismate mutase
AC610_08510	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AC610_08525	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AC610_08530	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AC610_08535	COG0583	DNA-binding transcription factor activity
AC610_08600	COG4191	Histidine kinase
AC610_08600	COG0784	Response regulator, receiver
AC610_08610	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
AC610_08630	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AC610_08640	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
AC610_08650	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AC610_08665	COG1595	DNA-templated transcription, initiation
AC610_08715	COG2244	polysaccharide biosynthetic process
AC610_08745	COG2264	protein methyltransferase activity
AC610_08770	COG1136	(ABC) transporter
AC610_08780	COG0477	Major facilitator Superfamily
AC610_08785	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AC610_08800	COG1253	flavin adenine dinucleotide binding
AC610_08810	COG0306	phosphate transporter
AC610_08835	COG0504	CTP synthase activity
AC610_08840	COG2877	3-deoxy-8-phosphooctulonate synthase activity
AC610_08850	COG0148	phosphopyruvate hydratase activity
AC610_08855	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AC610_08865	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AC610_08870	COG0585	pseudouridine synthase activity
AC610_08875	COG2840	Smr protein MutS2
AC610_08880	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AC610_08885	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AC610_08890	COG1238	metal cluster binding
AC610_08900	COG3737	Protein of unknown function (DUF498/DUF598)
AC610_08905	COG1534	Rna-binding protein
AC610_08910	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AC610_08915	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AC610_08920	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AC610_08925	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AC610_08930	COG1923	regulation of RNA biosynthetic process
AC610_08935	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AC610_08940	COG1546	Belongs to the CinA family
AC610_08950	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AC610_08955	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AC610_08960	COG2137	regulation of response to DNA damage stimulus
AC610_08965	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AC610_08970	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
AC610_08995	COG0583	DNA-binding transcription factor activity
AC610_09020	COG0351	phosphomethylpyrimidine kinase
AC610_09035	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AC610_09040	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AC610_09055	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AC610_09065	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AC610_09070	COG3734	2-keto-3-deoxy-galactonokinase
AC610_09080	COG4948	Mandelate Racemase Muconate Lactonizing
AC610_09085	COG0800	Aldolase
AC610_09125	COG1501	Belongs to the glycosyl hydrolase 31 family
AC610_09135	COG1070	Carbohydrate kinase
AC610_09140	COG2115	Belongs to the xylose isomerase family
AC610_09145	COG0477	Major facilitator Superfamily
AC610_09155	COG3328	transposase activity
AC610_09170	COG0860	N-Acetylmuramoyl-L-alanine amidase
AC610_09175	COG1469	GTP cyclohydrolase I activity
AC610_09200	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AC610_09205	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AC610_09210	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AC610_09215	COG0166	Belongs to the GPI family
AC610_09235	COG1472	Belongs to the glycosyl hydrolase 3 family
AC610_09245	COG4251	negative regulation of phosphorylation
AC610_09245	COG3706	GGDEF domain
AC610_09245	COG2203	Gaf domain
AC610_09245	COG5001	Diguanylate cyclase
AC610_09255	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
AC610_09260	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
AC610_09270	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AC610_09275	COG0671	phosphoesterase, PA-phosphatase related
AC610_09285	COG1794	racemase activity, acting on amino acids and derivatives
AC610_09290	COG0697	spore germination
AC610_09295	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AC610_09300	COG0167	dihydroorotate dehydrogenase activity
AC610_09315	COG1012	belongs to the aldehyde dehydrogenase family
AC610_09330	COG3328	transposase activity
AC610_09335	COG3328	transposase activity
AC610_09340	COG0366	Alpha amylase catalytic
AC610_09355	COG1082	Xylose isomerase domain protein TIM barrel
AC610_09365	COG2211	Major facilitator Superfamily
AC610_09380	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AC610_09385	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AC610_09390	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AC610_09395	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AC610_09400	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AC610_09405	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AC610_09405	COG0072	phenylalanine-tRNA ligase activity
AC610_09410	COG0776	regulation of translation
AC610_09455	COG0438	transferase activity, transferring glycosyl groups
AC610_09460	COG0438	transferase activity, transferring glycosyl groups
AC610_09495	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AC610_09505	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AC610_09525	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AC610_09535	COG1960	acyl-CoA dehydrogenase activity
AC610_09545	COG3040	lipid binding
AC610_09560	COG0322	excinuclease ABC activity
AC610_09575	COG0784	Response regulator, receiver
AC610_09575	COG4191	Histidine kinase
AC610_09595	COG1194	a g-specific adenine glycosylase
AC610_09600	COG0552	protein localization to endoplasmic reticulum
AC610_09610	COG3938	Belongs to the proline racemase family
AC610_09615	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AC610_09630	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AC610_09640	COG0006	proline dipeptidase activity
AC610_09655	COG0531	amino acid
AC610_09770	COG3328	transposase activity
AC610_09815	COG3328	transposase activity
AC610_09830	COG2801	Transposase and inactivated derivatives
AC610_09835	COG2963	transposase activity
AC610_09840	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
AC610_09845	COG3328	transposase activity
AC610_09850	COG0460	homoserine dehydrogenase
AC610_09850	COG0527	aspartate kinase activity
AC610_09885	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AC610_09890	COG0124	histidyl-tRNA synthetase
AC610_09905	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AC610_09910	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AC610_09915	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AC610_09920	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AC610_09920	COG0131	Imidazoleglycerol-phosphate dehydratase
AC610_09925	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AC610_09930	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AC610_09935	COG0107	imidazoleglycerol-phosphate synthase activity
AC610_09940	COG0140	phosphoribosyl-ATP diphosphatase activity
AC610_09940	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AC610_09955	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
AC610_09960	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
AC610_09965	COG0235	Class ii aldolase
AC610_09970	COG0531	amino acid
AC610_09975	COG0531	amino acid
AC610_09985	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AC610_09990	COG0277	FAD linked oxidase domain protein
AC610_10010	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AC610_10055	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AC610_10060	COG2258	MOSC domain
AC610_10065	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AC610_10070	COG0505	Belongs to the CarA family
AC610_10080	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AC610_10085	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AC610_10095	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AC610_10110	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AC610_10115	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AC610_10130	COG2198	Histidine kinase
AC610_10130	COG0784	Response regulator, receiver
AC610_10130	COG2205	protein histidine kinase activity
AC610_10135	COG1024	Enoyl-CoA hydratase
AC610_10140	COG0318	PFAM AMP-dependent synthetase and ligase
AC610_10175	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AC610_10185	COG2201	protein-glutamate methylesterase activity
AC610_10190	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
AC610_10200	COG0840	transmembrane signaling receptor activity
AC610_10210	COG0835	chemotaxis
AC610_10220	COG0840	transmembrane signaling receptor activity
AC610_10225	COG0840	transmembrane signaling receptor activity
AC610_10230	COG0840	transmembrane signaling receptor activity
AC610_10235	COG0840	transmembrane signaling receptor activity
AC610_10240	COG0840	transmembrane signaling receptor activity
AC610_10250	COG0840	transmembrane signaling receptor activity
AC610_10255	COG0840	transmembrane signaling receptor activity
AC610_10260	COG0840	transmembrane signaling receptor activity
AC610_10265	COG0840	transmembrane signaling receptor activity
AC610_10275	COG0840	transmembrane signaling receptor activity
AC610_10280	COG0840	transmembrane signaling receptor activity
AC610_10290	COG0840	transmembrane signaling receptor activity
AC610_10295	COG0840	transmembrane signaling receptor activity
AC610_10305	COG0745	RESPONSE REGULATOR receiver
AC610_10315	COG0835	chemotaxis
AC610_10320	COG1192	Involved in chromosome partitioning
AC610_10325	COG1360	Flagellar Motor Protein
AC610_10330	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AC610_10370	COG2198	Histidine kinase
AC610_10370	COG0643	Histidine kinase
AC610_10390	COG0455	bacterial-type flagellum organization
AC610_10400	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AC610_10420	COG3039	Transposase
AC610_10430	COG1684	flagellar biosynthetic protein fliR
AC610_10435	COG1987	bacterial-type flagellum assembly
AC610_10440	COG3039	Transposase
AC610_10450	COG3190	flagellar
AC610_10500	COG1677	Flagellar hook-basal body complex protein FliE
AC610_10525	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AC610_10540	COG3328	transposase activity
AC610_10570	COG1028	Short-chain dehydrogenase reductase Sdr
AC610_10575	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AC610_10590	COG2204	response regulator
AC610_10595	COG2201	protein-glutamate methylesterase activity
AC610_10625	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
AC610_10635	COG3039	Transposase
AC610_10640	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AC610_10650	COG3951	Flagellar rod assembly protein muramidase FlgJ
AC610_10650	COG1705	Flagellar rod assembly protein muramidase FlgJ
AC610_10655	COG1706	bacterial-type flagellum-dependent cell motility
AC610_10660	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
AC610_10665	COG4786	Flagellar basal body rod
AC610_10680	COG4787	bacterial-type flagellum-dependent cell motility
AC610_10685	COG1749	Flagellar hook protein flgE
AC610_10690	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
AC610_10695	COG1558	bacterial-type flagellum-dependent cell motility
AC610_10705	COG0784	Response regulator, receiver
AC610_10705	COG0835	chemotaxis
AC610_10730	COG5002	protein histidine kinase activity
AC610_10740	COG4585	Histidine kinase
AC610_10760	COG2915	High frequency lysogenization protein hflD homolog
AC610_10765	COG0482	sulfurtransferase activity
AC610_10775	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AC610_10780	COG0542	response to heat
AC610_10785	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AC610_10790	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AC610_10800	COG0492	ferredoxin-NADP+ reductase activity
AC610_10805	COG1674	ftsk spoiiie
AC610_10815	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AC610_10825	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AC610_10830	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AC610_10835	COG0183	Belongs to the thiolase family
AC610_10840	COG1250	3-hydroxyacyl-CoA dehydrogenase
AC610_10840	COG1024	Enoyl-CoA hydratase
AC610_10850	COG0105	UTP biosynthetic process
AC610_10875	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AC610_10880	COG1160	GTP binding
AC610_10885	COG0303	'Molybdopterin
AC610_10890	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AC610_10925	COG0708	Exodeoxyribonuclease III
AC610_10935	COG0303	'Molybdopterin
AC610_10940	COG0746	molybdenum cofactor guanylyltransferase activity
AC610_10965	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AC610_10965	COG1648	precorrin-2 dehydrogenase activity
AC610_10975	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AC610_10980	COG2223	nitrite transmembrane transporter activity
AC610_10985	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AC610_10995	COG0243	molybdopterin cofactor binding
AC610_11010	COG3685	Protein conserved in bacteria
AC610_11030	COG5001	Diguanylate cyclase
AC610_11040	COG4566	intracellular signal transduction
AC610_11090	COG3328	transposase activity
AC610_11100	COG3039	Transposase
AC610_11105	COG3328	transposase activity
AC610_11115	COG3328	transposase activity
AC610_11125	COG1073	alpha beta
AC610_11125	COG2226	methyltransferase
AC610_11140	COG0363	glucosamine-6-phosphate deaminase activity
AC610_11160	COG3328	transposase activity
AC610_11235	COG3328	transposase activity
AC610_11245	COG1192	Involved in chromosome partitioning
AC610_11290	COG3318	Belongs to the UPF0149 family
AC610_11290	COG3012	SEC-C Motif Domain Protein
AC610_11330	COG3328	transposase activity
AC610_11360	COG1309	transcriptional regulator
AC610_11375	COG2154	pterin-4-alpha-carbinolamine dehydratase
AC610_11385	COG0428	transporter
AC610_11390	COG3064	Membrane
AC610_11400	COG1530	ribonuclease E activity
AC610_11405	COG3039	Transposase
AC610_11435	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AC610_11460	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AC610_11465	COG0322	excinuclease ABC activity
AC610_11475	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AC610_11480	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AC610_11485	COG1663	tetraacyldisaccharide 4'-kinase activity
AC610_11490	COG1132	(ABC) transporter
AC610_11500	COG0811	peptide transport
AC610_11515	COG1136	(ABC) transporter
AC610_11520	COG4591	ABC-type transport system involved in lipoprotein release permease component
AC610_11530	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AC610_11535	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AC610_11550	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AC610_11560	COG0354	folic acid binding
AC610_11570	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AC610_11575	COG0837	glucose binding
AC610_11580	COG0363	glucosamine-6-phosphate deaminase activity
AC610_11585	COG0129	dihydroxy-acid dehydratase activity
AC610_11590	COG0800	Aldolase
AC610_11660	COG0784	Response regulator, receiver
AC610_11660	COG2205	protein histidine kinase activity
AC610_11665	COG2183	response to ionizing radiation
AC610_11675	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AC610_11675	COG0723	plastoquinol--plastocyanin reductase activity
AC610_11690	COG3243	poly(R)-hydroxyalkanoic acid synthase
AC610_11700	COG1183	phosphatidylcholine synthase activity
AC610_11705	COG1028	Short-chain dehydrogenase reductase Sdr
AC610_11720	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AC610_11735	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AC610_11740	COG0590	tRNA wobble adenosine to inosine editing
AC610_11745	COG1321	iron dependent repressor
AC610_11750	COG1914	H( )-stimulated, divalent metal cation uptake system
AC610_11770	COG2814	Major facilitator Superfamily
AC610_11785	COG1335	isochorismatase
AC610_11805	COG2197	response regulator
AC610_11840	COG0583	DNA-binding transcription factor activity
AC610_11845	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AC610_11850	COG3002	Belongs to the UPF0753 family
AC610_11860	COG0604	alcohol dehydrogenase
AC610_11865	COG3384	dioxygenase
AC610_11875	COG2801	Transposase and inactivated derivatives
AC610_11880	COG2963	transposase activity
AC610_11925	COG0519	Catalyzes the synthesis of GMP from XMP
AC610_11925	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AC610_11935	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AC610_11945	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AC610_11945	COG0475	glutathione-regulated potassium exporter activity
AC610_11950	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AC610_11960	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AC610_11965	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
AC610_11975	COG0776	regulation of translation
AC610_11980	COG0539	negative regulation of cytoplasmic translation
AC610_11985	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AC610_11990	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AC610_12000	COG2957	Belongs to the agmatine deiminase family
AC610_12005	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AC610_12030	COG0395	ABC-type sugar transport system, permease component
AC610_12035	COG1175	transmembrane transport
AC610_12070	COG2350	Protein conserved in bacteria
AC610_12075	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AC610_12080	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AC610_12085	COG1187	pseudouridine synthase activity
AC610_12100	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AC610_12105	COG0436	Aminotransferase
AC610_12110	COG4133	protoheme IX ABC transporter activity
AC610_12130	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
AC610_12155	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AC610_12165	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AC610_12170	COG4988	ABC transporter
AC610_12180	COG1294	oxidase, subunit
AC610_12210	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AC610_12215	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AC610_12225	COG0165	Argininosuccinate lyase
AC610_12230	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AC610_12240	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AC610_12255	COG0137	argininosuccinate synthase activity
AC610_12260	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AC610_12270	COG0215	cysteine-tRNA ligase activity
AC610_12275	COG2166	iron-sulfur cluster assembly
AC610_12285	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AC610_12295	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AC610_12300	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AC610_12325	COG4302	ethanolamine ammonia-lyase activity
AC610_12350	COG3039	Transposase
AC610_12380	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AC610_12385	COG0402	S-adenosylhomocysteine deaminase activity
AC610_12395	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AC610_12400	COG1509	lysine 2,3-aminomutase activity
AC610_12405	COG5001	Diguanylate cyclase
AC610_12405	COG3300	MHYT domain
AC610_12420	COG0483	inositol monophosphate 1-phosphatase activity
AC610_12445	COG0513	Belongs to the DEAD box helicase family
AC610_12450	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AC610_12455	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AC610_12475	COG0625	glutathione transferase activity
AC610_12485	COG4681	YaeQ
AC610_12490	COG2081	HI0933 family
AC610_12500	COG0501	Belongs to the peptidase M48B family
AC610_12505	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AC610_12510	COG1028	Short-chain dehydrogenase reductase Sdr
AC610_12530	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AC610_12535	COG0860	N-Acetylmuramoyl-L-alanine amidase
AC610_12540	COG0802	atpase or kinase
AC610_12545	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AC610_12545	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AC610_12550	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AC610_12555	COG1570	exodeoxyribonuclease VII activity
AC610_12565	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AC610_12605	COG0835	chemotaxis
AC610_12610	COG0840	transmembrane signaling receptor activity
AC610_12615	COG2094	Belongs to the DNA glycosylase MPG family
AC610_12620	COG1201	RNA secondary structure unwinding
AC610_12635	COG2969	positive regulation of protein catabolic process
AC610_12640	COG0625	glutathione transferase activity
AC610_12645	COG2857	Cytochrome c1
AC610_12650	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AC610_12655	COG0723	plastoquinol--plastocyanin reductase activity
AC610_12660	COG0741	lytic transglycosylase activity
AC610_12675	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AC610_12680	COG1702	phosphate starvation-inducible protein PhoH
AC610_12690	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AC610_12700	COG4535	Mg2 and Co2 transporter CorC
AC610_12715	COG1012	belongs to the aldehyde dehydrogenase family
AC610_12725	COG1177	transmembrane transport
AC610_12730	COG1176	ABC-type spermidine putrescine transport system, permease component I
AC610_12735	COG3842	ATPase activity
AC610_12755	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AC610_12770	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AC610_12775	COG0174	glutamine synthetase
AC610_12780	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AC610_12785	COG0745	RESPONSE REGULATOR receiver
AC610_12785	COG3706	GGDEF domain
AC610_12790	COG2703	oxygen carrier activity
AC610_12795	COG0477	Major facilitator Superfamily
AC610_12805	COG0243	molybdopterin cofactor binding
AC610_12810	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AC610_12830	COG2733	membrane
AC610_12835	COG5002	protein histidine kinase activity
AC610_12835	COG2205	protein histidine kinase activity
AC610_12835	COG0784	Response regulator, receiver
AC610_12845	COG0477	Major facilitator Superfamily
AC610_12850	COG0840	transmembrane signaling receptor activity
AC610_12880	COG2902	Dehydrogenase
AC610_12890	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AC610_12895	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AC610_12900	COG1609	Transcriptional regulator
AC610_12905	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AC610_12905	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AC610_12910	COG1105	Belongs to the carbohydrate kinase PfkB family
AC610_12915	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AC610_12915	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AC610_12930	COG3328	transposase activity
AC610_12935	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AC610_12945	COG1862	Preprotein translocase
AC610_12950	COG0343	queuine tRNA-ribosyltransferase activity
AC610_12955	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AC610_13000	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AC610_13005	COG3291	Pkd domain containing protein
AC610_13015	COG0405	Gamma-glutamyltransferase
AC610_13020	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AC610_13035	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AC610_13040	COG0742	ribosomal rna small subunit methyltransferase
AC610_13045	COG0326	Molecular chaperone. Has ATPase activity
AC610_13090	COG3328	transposase activity
AC610_13155	COG2948	multi-organism process
AC610_13175	COG3505	Type IV secretory pathway VirD4
AC610_13190	COG0556	nucleotide-excision repair
AC610_13260	COG2801	Transposase and inactivated derivatives
AC610_13265	COG2963	transposase activity
AC610_13360	COG3179	chitinase
AC610_13405	COG4695	Portal protein
AC610_13430	COG2963	transposase activity
AC610_13435	COG2801	Transposase and inactivated derivatives
AC610_13480	COG3275	phosphorelay sensor kinase activity
AC610_13485	COG1611	Belongs to the LOG family
AC610_13495	COG2095	MarC family integral membrane protein
AC610_13505	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AC610_13510	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AC610_13540	COG1185	polyribonucleotide nucleotidyltransferase activity
AC610_13545	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AC610_13550	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AC610_13555	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AC610_13560	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AC610_13565	COG0195	Participates in both transcription termination and antitermination
AC610_13570	COG0779	Required for maturation of 30S ribosomal subunits
AC610_13580	COG1007	ATP synthesis coupled electron transport
AC610_13595	COG0713	ATP synthesis coupled electron transport
AC610_13605	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AC610_13610	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AC610_13620	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AC610_13625	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
AC610_13630	COG0649	NAD binding
AC610_13635	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AC610_13640	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AC610_13645	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AC610_13660	COG0149	triose-phosphate isomerase activity
AC610_13665	COG4221	oxidoreductase activity
AC610_13700	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AC610_13705	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AC610_13710	COG0159	tryptophan synthase activity
AC610_13720	COG0133	tryptophan synthase activity
AC610_13730	COG0135	phosphoribosylanthranilate isomerase activity
AC610_13735	COG0101	tRNA pseudouridine synthase activity
AC610_13755	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AC610_13760	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AC610_13765	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AC610_13770	COG2890	protein-(glutamine-N5) methyltransferase activity
AC610_13780	COG0688	phosphatidylethanolamine metabolic process
AC610_13790	COG0433	COG0433 Predicted ATPase
AC610_13810	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AC610_13815	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AC610_13840	COG0717	Belongs to the dCTP deaminase family
AC610_13845	COG0489	protein tyrosine kinase activity
AC610_13880	COG3590	peptidase
AC610_13905	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AC610_13910	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AC610_13915	COG2311	Membrane
AC610_13920	COG1047	Peptidyl-prolyl cis-trans
AC610_13925	COG0791	NLP P60 protein
AC610_13930	COG0791	NLP P60 protein
AC610_13940	COG4106	trans-aconitate 2-methyltransferase activity
AC610_13945	COG1301	dicarboxylic acid transport
AC610_13950	COG1785	Belongs to the alkaline phosphatase family
AC610_13955	COG0037	tRNA processing
AC610_13960	COG1722	exodeoxyribonuclease VII activity
AC610_13965	COG0142	geranyltranstransferase activity
AC610_13970	COG4104	PAAR repeat-containing protein
AC610_13980	COG0312	modulator of DNA gyrase
AC610_13985	COG3028	Belongs to the UPF0307 family
AC610_13990	COG0312	modulator of DNA gyrase
AC610_14000	COG3164	Protein of unknown function
AC610_14005	COG1530	ribonuclease E activity
AC610_14010	COG0424	maF-like protein
AC610_14015	COG2968	Membrane
AC610_14030	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AC610_14045	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AC610_14060	COG0495	leucyl-tRNA aminoacylation
AC610_14070	COG3118	belongs to the thioredoxin family
AC610_14090	COG5487	UPF0391 membrane protein
AC610_14095	COG2155	Conserved Protein
AC610_14100	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AC610_14150	COG1132	(ABC) transporter
AC610_14180	COG0745	RESPONSE REGULATOR receiver
AC610_14185	COG5000	phosphorelay sensor kinase activity
AC610_14185	COG5002	protein histidine kinase activity
AC610_14190	COG0475	glutathione-regulated potassium exporter activity
AC610_14195	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AC610_14200	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AC610_14215	COG0745	RESPONSE REGULATOR receiver
AC610_14215	COG3706	GGDEF domain
AC610_14220	COG1187	pseudouridine synthase activity
AC610_14225	COG5002	protein histidine kinase activity
AC610_14225	COG5001	Diguanylate cyclase
AC610_14235	COG1595	DNA-templated transcription, initiation
AC610_14350	COG0667	Aldo Keto reductase
AC610_14355	COG2814	Major facilitator Superfamily
AC610_14360	COG0583	DNA-binding transcription factor activity
AC610_14370	COG2207	Transcriptional regulator
AC610_14380	COG1309	transcriptional regulator
AC610_14385	COG1538	Outer membrane efflux protein
AC610_14390	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AC610_14405	COG0735	belongs to the Fur family
AC610_14410	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AC610_14435	COG4452	Inner membrane protein CreD
AC610_14455	COG0745	RESPONSE REGULATOR receiver
AC610_14460	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AC610_14480	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AC610_14490	COG2198	Histidine kinase
AC610_14490	COG0643	Histidine kinase
AC610_14495	COG0840	transmembrane signaling receptor activity
AC610_14500	COG0835	chemotaxis
AC610_14505	COG2200	EAL domain
AC610_14505	COG2199	diguanylate cyclase activity
AC610_14505	COG2202	Pas domain
AC610_14510	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AC610_14515	COG2201	protein-glutamate methylesterase activity
AC610_14525	COG3590	peptidase
AC610_14540	COG1515	deoxyribonuclease V activity
AC610_14555	COG1741	Belongs to the pirin family
AC610_14570	COG1741	Belongs to the pirin family
AC610_14575	COG1966	Carbon starvation protein
AC610_14580	COG2879	small protein
AC610_14625	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AC610_14630	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AC610_14635	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AC610_14640	COG2080	2 iron, 2 sulfur cluster binding
AC610_14645	COG0604	alcohol dehydrogenase
AC610_14645	COG1028	Short-chain dehydrogenase reductase Sdr
AC610_14645	COG3321	synthase
AC610_14650	COG4251	negative regulation of phosphorylation
AC610_14650	COG3706	GGDEF domain
AC610_14650	COG2203	Gaf domain
AC610_14650	COG5001	Diguanylate cyclase
AC610_14655	COG0629	single-stranded DNA binding
AC610_14660	COG0142	geranyltranstransferase activity
AC610_14670	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AC610_14685	COG0527	aspartate kinase activity
AC610_14690	COG0384	phenazine biosynthesis protein PhzF
AC610_14695	COG0384	phenazine biosynthesis protein PhzF
AC610_14705	COG1764	response to oxidative stress
AC610_14710	COG0540	Belongs to the ATCase OTCase family
AC610_14715	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AC610_14720	COG1678	Uncharacterized ACR, COG1678
AC610_14725	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
AC610_14730	COG0519	Catalyzes the synthesis of GMP from XMP
AC610_14755	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AC610_14770	COG0739	heme binding
AC610_14790	COG0693	protein deglycase activity
AC610_14800	COG1959	2 iron, 2 sulfur cluster binding
AC610_14805	COG0719	Fe-S assembly protein
AC610_14810	COG0396	ATPase activity
AC610_14815	COG0719	Fe-S assembly protein
AC610_14820	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AC610_14825	COG0456	acetyltransferase
AC610_14835	COG4774	siderophore transport
AC610_14840	COG3128	pkhd-type hydroxylase
AC610_14865	COG3328	transposase activity
AC610_14870	COG1477	protein flavinylation
AC610_14875	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AC610_14885	COG1555	photosystem II stabilization
AC610_14905	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AC610_14915	COG0628	permease
AC610_14925	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AC610_14940	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AC610_14960	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AC610_14965	COG0271	Belongs to the BolA IbaG family
AC610_14975	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AC610_14985	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AC610_14990	COG1137	ATPase activity
AC610_15005	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AC610_15010	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
AC610_15015	COG1660	Displays ATPase and GTPase activities
AC610_15025	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AC610_15040	COG2239	Acts as a magnesium transporter
AC610_15050	COG1294	oxidase, subunit
AC610_15120	COG2951	lytic endotransglycosylase activity
AC610_15125	COG4644	lycopene metabolic process
AC610_15185	COG1271	oxidase subunit
AC610_15195	COG1113	amino acid transport
AC610_15205	COG2963	transposase activity
AC610_15210	COG2801	Transposase and inactivated derivatives
AC610_15230	COG2197	response regulator
AC610_15235	COG0531	amino acid
AC610_15295	COG2814	Major facilitator Superfamily
AC610_15300	COG0754	glutathionylspermidine amidase activity
AC610_15325	COG1842	Phage shock protein A
AC610_15335	COG0259	pyridoxamine-phosphate oxidase activity
AC610_15340	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AC610_15345	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AC610_15355	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AC610_15360	COG2814	Major facilitator Superfamily
AC610_15385	COG2205	protein histidine kinase activity
AC610_15385	COG0784	Response regulator, receiver
AC610_15385	COG2198	Histidine kinase
AC610_15390	COG2353	YceI-like domain
AC610_15410	COG1760	l-serine dehydratase
AC610_15420	COG0527	aspartate kinase activity
AC610_15420	COG0460	homoserine dehydrogenase
AC610_15425	COG0626	cystathionine gamma-synthase activity
AC610_15430	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AC610_15435	COG0739	heme binding
AC610_15440	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AC610_15445	COG1272	protein, Hemolysin III
AC610_15450	COG2982	Protein involved in outer membrane biogenesis
AC610_15455	COG0517	IMP dehydrogenase activity
AC610_15455	COG0516	GMP reductase activity
AC610_15460	COG0463	Glycosyl transferase, family 2
AC610_15465	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AC610_15470	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AC610_15480	COG4771	TonB-dependent receptor
AC610_15485	COG1309	transcriptional regulator
AC610_15495	COG1960	acyl-CoA dehydrogenase activity
AC610_15520	COG3328	transposase activity
AC610_15540	COG0509	glycine decarboxylation via glycine cleavage system
AC610_15545	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AC610_15555	COG0330	HflC and HflK could
AC610_15560	COG1742	UPF0060 membrane protein
AC610_15575	COG0494	nUDIX hydrolase
AC610_15585	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AC610_15590	COG0837	glucose binding
AC610_15620	COG1388	LysM domain
AC610_15620	COG3858	chitin binding
AC610_15625	COG3525	Glycosyl hydrolase, family 20, catalytic domain
AC610_15635	COG1472	Belongs to the glycosyl hydrolase 3 family
AC610_15645	COG3537	Alpha-1,2-mannosidase
AC610_15680	COG3142	Participates in the control of copper homeostasis
AC610_15685	COG1446	asparaginase
AC610_15715	COG0840	transmembrane signaling receptor activity
AC610_15735	COG0189	ligase activity
AC610_15745	COG1397	ADP-ribosylglycohydrolase
AC610_15760	COG1199	ATP-dependent helicase activity
AC610_15770	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AC610_15775	COG1215	transferase activity, transferring glycosyl groups
AC610_15785	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AC610_15790	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AC610_15795	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
AC610_15800	COG0535	radical SAM domain protein
AC610_15805	COG0535	radical SAM domain protein
AC610_15820	COG0837	glucose binding
AC610_15830	COG3328	transposase activity
AC610_15840	COG1643	Atp-dependent helicase
AC610_15845	COG0783	Belongs to the Dps family
AC610_15850	COG0514	ATP-dependent DNA helicase (RecQ)
AC610_15905	COG0840	transmembrane signaling receptor activity
AC610_15925	COG3920	Histidine kinase
AC610_15940	COG0602	queuosine metabolic process
AC610_15950	COG2885	chlorophyll binding
AC610_15955	COG0823	Involved in the tonB-independent uptake of proteins
AC610_15965	COG0848	biopolymer transport protein
AC610_15975	COG0824	Thioesterase
AC610_15980	COG2255	four-way junction helicase activity
AC610_15990	COG3158	transport of potassium into the cell
AC610_15995	COG0632	four-way junction helicase activity
AC610_16000	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AC610_16005	COG0217	transcriptional regulatory protein
AC610_16020	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AC610_16035	COG0477	Major facilitator Superfamily
AC610_16055	COG0657	acetylesterase activity
AC610_16055	COG2755	lipolytic protein G-D-S-L family
AC610_16075	COG0488	(ABC) transporter
AC610_16105	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AC610_16105	COG4651	solute:proton antiporter activity
AC610_16130	COG4772	TonB-dependent receptor
AC610_16140	COG4264	IucA IucC family
AC610_16155	COG0019	diaminopimelate decarboxylase activity
AC610_16180	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
AC610_16190	COG1492	cobalamin metabolic process
AC610_16200	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
AC610_16220	COG4206	TonB-dependent receptor
AC610_16230	COG0542	response to heat
AC610_16280	COG1877	trehalose-phosphatase activity
AC610_16285	COG3387	PFAM Glycoside hydrolase 15-related
AC610_16315	COG0840	transmembrane signaling receptor activity
AC610_16320	COG3011	Protein conserved in bacteria
AC610_16335	COG0564	pseudouridine synthase activity
AC610_16340	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AC610_16350	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AC610_16350	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AC610_16365	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AC610_16370	COG0045	succinate-CoA ligase (ADP-forming) activity
AC610_16410	COG3328	transposase activity
AC610_16420	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
AC610_16425	COG0237	dephospho-CoA kinase activity
AC610_16445	COG0745	RESPONSE REGULATOR receiver
AC610_16455	COG0189	ligase activity
AC610_16480	COG2963	transposase activity
AC610_16485	COG2801	Transposase and inactivated derivatives
AC610_16500	COG2003	Belongs to the UPF0758 family
AC610_16520	COG3039	Transposase
AC610_16525	COG3328	transposase activity
AC610_16535	COG3328	transposase activity
AC610_16540	COG1196	nuclear chromosome segregation
AC610_16580	COG1192	Involved in chromosome partitioning
AC610_16650	COG0270	DNA (cytosine-5-)-methyltransferase activity
AC610_16735	COG3328	transposase activity
AC610_16865	COG5001	Diguanylate cyclase
AC610_16960	COG0583	DNA-binding transcription factor activity
AC610_16980	COG0582	viral genome integration into host DNA
AC610_17000	COG2022	thiamine diphosphate biosynthetic process
AC610_17005	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AC610_17010	COG0471	metal ion transport
AC610_17010	COG3273	potassium ion transport
AC610_17035	COG1970	mechanosensitive ion channel activity
AC610_17050	COG1609	Transcriptional regulator
AC610_17060	COG3250	beta-galactosidase activity
AC610_17065	COG4948	Mandelate Racemase Muconate Lactonizing
AC610_17075	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AC610_17085	COG0308	aminopeptidase N
AC610_17090	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AC610_17100	COG2895	sulfate adenylyltransferase (ATP) activity
AC610_17100	COG0529	Catalyzes the synthesis of activated sulfate
AC610_17105	COG0175	sulfate reduction
AC610_17110	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AC610_17115	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AC610_17120	COG0175	sulfate reduction
AC610_17170	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
AC610_17175	COG3588	fructose-bisphosphate aldolase
AC610_17180	COG0469	pyruvate kinase activity
AC610_17190	COG0126	phosphoglycerate kinase activity
AC610_17220	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AC610_17230	COG3047	cAMP biosynthetic process
AC610_17245	COG3453	Protein conserved in bacteria
AC610_17245	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AC610_17250	COG0725	ABC transporter, periplasmic molybdate-binding protein
AC610_17255	COG4149	molybdate abc transporter
AC610_17260	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AC610_17280	COG0642	Histidine kinase
AC610_17285	COG0745	RESPONSE REGULATOR receiver
AC610_17305	COG1022	Amp-dependent synthetase and ligase
AC610_17330	COG1376	ErfK ybiS ycfS ynhG family protein
AC610_17335	COG0739	heme binding
AC610_17355	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AC610_17360	COG1301	dicarboxylic acid transport
AC610_17370	COG2304	oxidoreductase activity
AC610_17390	COG0714	Associated with various cellular activities
AC610_17420	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AC610_17435	COG0254	rRNA binding
AC610_17440	COG1957	nucleoside hydrolase
AC610_17445	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AC610_17455	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AC610_17460	COG1758	RNA polymerase activity
AC610_17470	COG1561	YicC-like family, N-terminal region
AC610_17475	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AC610_17485	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AC610_17490	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AC610_17505	COG0006	proline dipeptidase activity
AC610_17515	COG0006	proline dipeptidase activity
AC610_17520	COG3079	Belongs to the UPF0149 family
AC610_17535	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AC610_17555	COG2912	Transglutaminase-like superfamily
AC610_17560	COG1773	rubredoxin
AC610_17565	COG0352	thiamine-phosphate diphosphorylase activity
AC610_17590	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AC610_17600	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
AC610_17605	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AC610_17635	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AC610_17640	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AC610_17645	COG1028	Short-chain dehydrogenase reductase Sdr
AC610_17655	COG0671	phosphoesterase, PA-phosphatase related
AC610_17660	COG3781	membrane
AC610_17670	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AC610_17675	COG0563	adenylate kinase activity
AC610_17690	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
AC610_17700	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AC610_17720	COG3710	Transcriptional regulator
AC610_17725	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AC610_17735	COG0840	transmembrane signaling receptor activity
AC610_17740	COG0405	Gamma-glutamyltransferase
AC610_17745	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AC610_17765	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AC610_17770	COG0473	3-isopropylmalate dehydrogenase activity
AC610_17775	COG0066	3-isopropylmalate dehydratase activity
AC610_17780	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AC610_17800	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AC610_17805	COG1538	Outer membrane efflux protein
AC610_17810	COG1519	Transferase
AC610_17815	COG1560	Kdo2-lipid A biosynthetic process
AC610_17840	COG0281	malic enzyme
AC610_17840	COG0280	phosphate acetyltransferase
AC610_17845	COG1301	dicarboxylic acid transport
AC610_17870	COG0583	DNA-binding transcription factor activity
AC610_17880	COG0667	Aldo Keto reductase
AC610_17895	COG2197	response regulator
AC610_17900	COG1840	ABC-type Fe3 transport system, periplasmic component
AC610_17905	COG0642	Histidine kinase
AC610_17920	COG2851	Citrate transporter
AC610_17925	COG1028	Short-chain dehydrogenase reductase Sdr
AC610_17930	COG1609	Transcriptional regulator
AC610_17935	COG2211	Major facilitator Superfamily
AC610_17960	COG1162	GTPase activity
AC610_17965	COG0436	Aminotransferase
AC610_17980	COG0726	polysaccharide deacetylase
AC610_17985	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AC610_18000	COG3964	amidohydrolase
AC610_18005	COG0402	S-adenosylhomocysteine deaminase activity
AC610_18030	COG3328	transposase activity
AC610_18040	COG1307	EDD domain protein, DegV family
AC610_18050	COG2963	transposase activity
AC610_18055	COG2801	Transposase and inactivated derivatives
AC610_18060	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
AC610_18065	COG3791	Glutathione-dependent formaldehyde-activating
AC610_18090	COG0745	RESPONSE REGULATOR receiver
AC610_18095	COG2205	protein histidine kinase activity
AC610_18130	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AC610_18140	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AC610_18145	COG1012	belongs to the aldehyde dehydrogenase family
AC610_18150	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
AC610_18175	COG1183	phosphatidylcholine synthase activity
AC610_18185	COG0442	prolyl-tRNA aminoacylation
AC610_18200	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AC610_18205	COG1127	ABC transporter
AC610_18210	COG3218	ABC-type transport auxiliary lipoprotein component
AC610_18210	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AC610_18240	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AC610_18245	COG0662	Cupin 2, conserved barrel domain protein
AC610_18245	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
AC610_18275	COG2086	electron transfer activity
AC610_18290	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AC610_18290	COG0546	phosphoglycolate phosphatase activity
AC610_18295	COG0277	FAD linked oxidase domain protein
AC610_18305	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AC610_18340	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
AC610_18345	COG0438	transferase activity, transferring glycosyl groups
AC610_18385	COG0626	cystathionine gamma-synthase activity
AC610_18415	COG0625	glutathione transferase activity
AC610_18425	COG0513	Belongs to the DEAD box helicase family
AC610_18430	COG0720	synthase
AC610_18440	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AC610_18450	COG1956	GAF domain-containing protein
AC610_18465	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AC610_18470	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AC610_18480	COG4991	sh3 domain protein
AC610_18490	COG0339	signal peptide processing
AC610_18505	COG2132	Multicopper oxidase
AC610_18540	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AC610_18545	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AC610_18550	COG1136	(ABC) transporter
AC610_18555	COG1136	(ABC) transporter
AC610_18555	COG0577	efflux transmembrane transporter activity
AC610_18570	COG2204	response regulator
AC610_18575	COG4191	Histidine kinase
AC610_18580	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AC610_18595	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AC610_18600	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AC610_18605	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AC610_18610	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AC610_18615	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AC610_18620	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AC610_18630	COG0356	it plays a direct role in the translocation of protons across the membrane
AC610_18650	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AC610_18660	COG0508	dehydrogenase complex catalyzes the overall conversion of
AC610_18700	COG2011	ABC-type metal ion transport system permease component
AC610_18705	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AC610_18710	COG0697	spore germination
AC610_18715	COG1666	GTP binding
AC610_18725	COG2198	Histidine kinase
AC610_18725	COG5002	protein histidine kinase activity
AC610_18725	COG0784	Response regulator, receiver
AC610_18750	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AC610_18755	COG1187	pseudouridine synthase activity
AC610_18760	COG2813	Specifically methylates the guanine in position
AC610_18770	COG3039	Transposase
AC610_18775	COG3328	transposase activity
AC610_18790	COG2202	Pas domain
AC610_18790	COG2205	protein histidine kinase activity
AC610_18810	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AC610_18815	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AC610_18820	COG1522	sequence-specific DNA binding
AC610_18870	COG0842	Transport permease protein
AC610_18875	COG1131	(ABC) transporter
AC610_18880	COG0025	NhaP-type Na H and K H
AC610_18885	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
AC610_18890	COG1573	uracil-dna glycosylase
AC610_18900	COG3384	dioxygenase
AC610_18910	COG0583	DNA-binding transcription factor activity
AC610_18920	COG0667	Aldo Keto reductase
AC610_18930	COG3590	peptidase
AC610_18945	COG0531	amino acid
AC610_18960	COG2972	Histidine kinase
AC610_18975	COG3685	Protein conserved in bacteria
AC610_18980	COG3546	catalase activity
AC610_19030	COG1271	oxidase subunit
AC610_19035	COG1294	oxidase, subunit
AC610_19050	COG1028	Short-chain dehydrogenase reductase Sdr
AC610_19070	COG1063	alcohol dehydrogenase
AC610_19080	COG3328	transposase activity
AC610_19145	COG0251	oxidation-reduction process
AC610_19175	COG0659	secondary active sulfate transmembrane transporter activity
AC610_19180	COG0038	chloride channel
AC610_19190	COG0024	Methionine aminopeptidase
AC610_19225	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AC610_19230	COG1490	D-aminoacyl-tRNA deacylase activity
AC610_19235	COG1560	Kdo2-lipid A biosynthetic process
AC610_19285	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AC610_19285	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AC610_19290	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AC610_19295	COG0242	peptide deformylase activity
AC610_19300	COG1652	LysM domain
AC610_19305	COG0758	DNA mediated transformation
AC610_19325	COG1754	DNA topoisomerase type I activity
AC610_19325	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AC610_19330	COG0009	L-threonylcarbamoyladenylate synthase
AC610_19345	COG1028	Short-chain dehydrogenase reductase Sdr
AC610_19355	COG0616	signal peptide processing
AC610_19360	COG0534	Mate efflux family protein
AC610_19380	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AC610_19385	COG0625	glutathione transferase activity
AC610_19405	COG2860	membrane
AC610_19410	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AC610_19415	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AC610_19420	COG2201	protein-glutamate methylesterase activity
AC610_19425	COG2177	Part of the ABC transporter FtsEX involved in
AC610_19430	COG2884	Cell division ATP-binding protein ftsE
AC610_19435	COG0513	Belongs to the DEAD box helicase family
AC610_19440	COG3118	belongs to the thioredoxin family
AC610_19445	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AC610_19455	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
AC610_19480	COG1652	LysM domain
AC610_19485	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AC610_19485	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AC610_19490	COG1473	amidohydrolase
AC610_19495	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AC610_19500	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AC610_19520	COG5383	Protein conserved in bacteria
AC610_19545	COG3328	transposase activity
AC610_19565	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
AC610_19570	COG3023	N-Acetylmuramoyl-L-alanine amidase
AC610_19590	COG0531	amino acid
AC610_19610	COG3328	transposase activity
AC610_19620	COG2133	pyrroloquinoline quinone binding
AC610_19640	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AC610_19645	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AC610_19650	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AC610_19655	COG1610	YqeY-like protein
AC610_19665	COG1295	ribonuclease BN
AC610_19670	COG0358	DNA primase activity
AC610_19685	COG0109	protoheme IX farnesyltransferase activity
AC610_19715	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
AC610_19730	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AC610_19770	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AC610_19775	COG0739	heme binding
AC610_19780	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AC610_19790	COG2223	nitrite transmembrane transporter activity
AC610_19795	COG0708	Exodeoxyribonuclease III
AC610_19800	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AC610_19810	COG1192	Involved in chromosome partitioning
AC610_19815	COG1475	DNA binding
AC610_19830	COG0463	Glycosyl transferase, family 2
AC610_19850	COG0756	dUTP diphosphatase activity
AC610_19855	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AC610_19860	COG2003	Belongs to the UPF0758 family
AC610_19865	COG0018	arginyl-trna synthetase
AC610_19880	COG4221	oxidoreductase activity
AC610_19890	COG2755	lipolytic protein G-D-S-L family
AC610_19890	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AC610_19900	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AC610_19905	COG1166	arginine decarboxylase activity
AC610_19910	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AC610_19935	COG3525	Glycosyl hydrolase, family 20, catalytic domain
AC610_19935	COG3291	Pkd domain containing protein
AC610_19950	COG0606	chelatase, subunit chli
AC610_19965	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AC610_20000	COG1690	Belongs to the RtcB family
AC610_20040	COG1090	epimerase
AC610_20045	COG0745	RESPONSE REGULATOR receiver
AC610_20050	COG0642	Histidine kinase
AC610_20070	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AC610_20095	COG1011	Hydrolase
AC610_20100	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AC610_20115	COG0753	catalase activity
AC610_20135	COG2197	response regulator
AC610_20140	COG4585	Histidine kinase
AC610_20145	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AC610_20150	COG1136	(ABC) transporter
AC610_20175	COG0697	spore germination
AC610_20195	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AC610_20200	COG0180	Tryptophanyl-tRNA synthetase
AC610_20205	COG3237	CsbD-like
AC610_20245	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AC610_20260	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AC610_20265	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
AC610_20265	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
AC610_20275	COG3228	Belongs to the MtfA family
AC610_20290	COG2205	protein histidine kinase activity
AC610_20295	COG0745	RESPONSE REGULATOR receiver
AC610_20305	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AC610_20345	COG3328	transposase activity
AC610_20360	COG1199	ATP-dependent helicase activity
AC610_20375	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AC610_20465	COG4555	ABC transporter
AC610_20475	COG1476	TRANSCRIPTIONal
AC610_20495	COG1230	cation diffusion facilitator family transporter
AC610_20500	COG0543	2 iron, 2 sulfur cluster binding
AC610_20500	COG0633	Ferredoxin
AC610_20505	COG1131	(ABC) transporter
AC610_20510	COG0842	Transport permease protein
AC610_20515	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AC610_20545	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AC610_20565	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AC610_20570	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AC610_20580	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AC610_20580	COG0045	succinate-CoA ligase (ADP-forming) activity
AC610_20580	COG1042	CoA-binding domain protein
AC610_20585	COG2239	Acts as a magnesium transporter
AC610_20610	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AC610_20615	COG3387	PFAM Glycoside hydrolase 15-related
AC610_20630	COG3100	YcgL domain-containing protein
AC610_20635	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AC610_20645	COG0463	Glycosyl transferase, family 2
AC610_20655	COG1028	Short-chain dehydrogenase reductase Sdr
AC610_20695	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AC610_20710	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AC610_20750	COG0408	coproporphyrinogen oxidase activity
AC610_20785	COG0515	serine threonine protein kinase
AC610_20790	COG0631	protein serine/threonine phosphatase activity
AC610_20815	COG0667	Aldo Keto reductase
AC610_20820	COG0583	DNA-binding transcription factor activity
AC610_20835	COG3501	Rhs element vgr protein
AC610_20890	COG0154	amidase activity
AC610_20920	COG3328	transposase activity
AC610_20925	COG3039	Transposase
AC610_21005	COG0210	DNA helicase
AC610_21020	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AC610_21025	COG0583	DNA-binding transcription factor activity
AC610_21030	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AC610_21040	COG2159	amidohydrolase
AC610_21045	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AC610_21050	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AC610_21070	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AC610_21090	COG0357	Ribosomal RNA small subunit methyltransferase G
AC610_21095	COG3540	Alkaline phosphatase
AC610_21105	COG2091	lysine biosynthetic process via aminoadipic acid
AC610_21125	COG0708	Exodeoxyribonuclease III
AC610_21130	COG1940	carbohydrate kinase activity
AC610_21130	COG1846	Transcriptional regulator
AC610_21150	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AC610_21155	COG3162	membrane
AC610_21165	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AC610_21190	COG3507	Belongs to the glycosyl hydrolase 43 family
AC610_21210	COG1028	Short-chain dehydrogenase reductase Sdr
AC610_21215	COG0179	Fumarylacetoacetate (FAA) hydrolase
AC610_21220	COG4948	Mandelate Racemase Muconate Lactonizing
AC610_21225	COG3254	rhamnose metabolic process
AC610_21230	COG0738	Major facilitator superfamily
AC610_21235	COG1414	Transcriptional regulator
AC610_21240	COG2207	Transcriptional regulator
AC610_21240	COG1917	Cupin 2, conserved barrel domain protein
AC610_21250	COG1971	Probably functions as a manganese efflux pump
AC610_21255	COG2205	protein histidine kinase activity
AC610_21265	COG3459	Glycosyltransferase 36 associated
AC610_21270	COG2211	Major facilitator Superfamily
AC610_21275	COG3265	gluconokinase activity
AC610_21280	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AC610_21300	COG2911	Protein conserved in bacteria
AC610_21305	COG0729	surface antigen
AC610_21310	COG4771	TonB-dependent receptor
AC610_21320	COG0457	Tetratricopeptide repeat
AC610_21330	COG0752	glycyl-tRNA synthetase alpha subunit
AC610_21335	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AC610_21345	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AC610_21345	COG0519	Catalyzes the synthesis of GMP from XMP
AC610_21360	COG0805	protein transport
AC610_21365	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AC610_21370	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AC610_21380	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AC610_21410	COG2974	May be involved in recombination
AC610_21415	COG0037	tRNA processing
AC610_21420	COG2115	Belongs to the xylose isomerase family
AC610_21430	COG3661	Belongs to the glycosyl hydrolase 67 family
AC610_21440	COG4948	Mandelate Racemase Muconate Lactonizing
AC610_21450	COG1472	Belongs to the glycosyl hydrolase 3 family
AC610_21455	COG0246	Mannitol dehydrogenase
AC610_21510	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AC610_21535	COG3386	PFAM SMP-30 Gluconolaconase
AC610_21545	COG3250	beta-galactosidase activity
AC610_21550	COG1904	glucuronate isomerase
AC610_21555	COG3693	PFAM glycoside hydrolase, family 10
AC610_21565	COG3693	PFAM glycoside hydrolase, family 10
AC610_21580	COG2211	Major facilitator Superfamily
AC610_21650	COG2937	Belongs to the GPAT DAPAT family
AC610_21685	COG0284	orotidine-5'-phosphate decarboxylase activity
AC610_21690	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
AC610_21695	COG3132	Protein of unknown function, DUF480
AC610_21705	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AC610_21760	COG0210	DNA helicase
AC610_21765	COG1435	thymidine kinase activity
AC610_21775	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
AC610_21795	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AC610_21825	COG3135	benzoate transporter
AC610_21850	COG0676	glucose-6-phosphate 1-epimerase activity
AC610_21860	COG3012	SEC-C Motif Domain Protein
AC610_21925	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AC610_21935	COG4221	oxidoreductase activity
AC610_21940	COG0583	DNA-binding transcription factor activity
AC610_21950	COG0477	Major facilitator Superfamily
AC610_21955	COG1289	transmembrane transporter activity
AC610_21965	COG1566	PFAM secretion protein HlyD family protein
AC610_21980	COG0302	gtp cyclohydrolase
AC610_22000	COG3328	transposase activity
AC610_22010	COG0730	response to heat
AC610_22025	COG3328	transposase activity
AC610_22050	COG0564	pseudouridine synthase activity
AC610_22145	COG4790	Type iii secretion
AC610_22165	COG1157	protein secretion by the type III secretion system
AC610_22175	COG4789	Type iii secretion
AC610_22280	COG3039	Transposase
AC610_22320	COG2963	transposase activity
AC610_22325	COG2801	Transposase and inactivated derivatives
AC610_22365	COG2801	Transposase and inactivated derivatives
AC610_22370	COG2963	transposase activity
AC610_22395	COG0439	Biotin carboxylase
AC610_22425	COG1028	Short-chain dehydrogenase reductase Sdr
AC610_22465	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AC610_22470	COG1074	ATP-dependent DNA helicase activity
AC610_22475	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AC610_22510	COG1127	ABC transporter
AC610_22515	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AC610_22520	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AC610_22535	COG2853	Lipoprotein
AC610_22550	COG0386	Belongs to the glutathione peroxidase family
AC610_22560	COG1322	Protein conserved in bacteria
AC610_22570	COG0583	DNA-binding transcription factor activity
AC610_22595	COG0531	amino acid
AC610_22600	COG3537	Alpha-1,2-mannosidase
AC610_22610	COG2203	Gaf domain
AC610_22610	COG2199	diguanylate cyclase activity
AC610_22615	COG3835	regulator
AC610_22620	COG1929	Belongs to the glycerate kinase type-1 family
AC610_22640	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AC610_22645	COG0861	Integral membrane protein TerC family
AC610_22655	COG0584	glycerophosphoryl diester phosphodiesterase
AC610_22670	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AC610_22675	COG0726	polysaccharide deacetylase
AC610_22680	COG0706	membrane insertase activity
AC610_22685	COG0594	ribonuclease P activity
AC610_22690	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AC610_22805	COG3328	transposase activity
AC610_22855	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AC610_22860	COG4691	Plasmid stability protein
AC610_22865	COG1487	ribonuclease activity
AC610_22880	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AC610_22930	COG3846	protein secretion by the type IV secretion system
AC610_22940	COG3451	type IV secretory pathway VirB4
AC610_22950	COG4962	Type ii secretion system protein e
AC610_23090	COG3328	transposase activity
AC610_23105	COG3039	Transposase
AC610_23130	COG3328	transposase activity
AC610_23175	COG3328	transposase activity
AC610_23225	COG1487	ribonuclease activity
AC610_23230	COG4691	Plasmid stability protein
AC610_23235	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AC610_23325	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)