locus-tag	class	description
AC611_00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
AC611_00015	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
AC611_00020	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AC611_00030	ENOG4108K0D	peptidase, M48
AC611_00080	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
AC611_00090	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
AC611_00115	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
AC611_00135	ENOG4105CN1	protease
AC611_00140	ENOG41063SB	peptidase
AC611_00150	ENOG4107VAM	peptidase, m28
AC611_00180	ENOG4105DQ4	alcohol dehydrogenase
AC611_00190	ENOG4105BZ8	glutamate synthase
AC611_00195	ENOG4105CBC	glutamate synthase
AC611_00220	ENOG4105EXG	Transcriptional regulator
AC611_00280	ENOG4108I5C	dEAD DEAH box helicase
AC611_00285	ENOG4108UT2	hemolysin iii
AC611_00295	ENOG4107FW0	short-chain dehydrogenase reductase
AC611_00300	ENOG4105CHR	reductase
AC611_00330	ENOG4105DYS	nad(p)h dehydrogenase (quinone)
AC611_00340	ENOG4105F2I	Transposase
AC611_00350	ENOG4105F2I	Transposase
AC611_00365	ENOG41067RQ	csbd family
AC611_00390	ENOG4105D4Y	metalloprotease
AC611_00415	ENOG4105K63	Thioredoxin
AC611_00420	ENOG4105CSH	Transporter
AC611_00460	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
AC611_00500	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AC611_00505	ENOG4105CGF	Aromatic amino acid aminotransferase
AC611_00510	ENOG4105CHB	tonB-dependent Receptor
AC611_00535	ENOG4105DMF	Dehydrogenase
AC611_00545	ENOG4105BZU	Histidine kinase
AC611_00550	ENOG4105WH1	Two component transcriptional regulator luxr family
AC611_00575	ENOG4105RKW	reductase (By
AC611_00580	ENOG4105F2I	Transposase
AC611_00600	ENOG4105EP6	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity)
AC611_00605	ENOG4105CG3	alpha amylase, catalytic region
AC611_00610	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
AC611_00625	ENOG4105EBR	Carboxylesterase
AC611_00640	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
AC611_00650	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
AC611_00655	ENOG4105DSG	hydrolase family 43
AC611_00660	ENOG4105ETE	Transcriptional regulator (LacI family
AC611_00665	ENOG4105D50	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate (By similarity)
AC611_00670	ENOG4105CHR	reductase
AC611_00680	ENOG4107TDE	lipolytic protein G-D-S-L family
AC611_00690	ENOG4105MIR	Phenylalanine 4-monooxygenase
AC611_00695	ENOG4108YXU	transcriptional regulator AsnC family
AC611_00700	ENOG4105CNM	Receptor
AC611_00705	ENOG4105D78	K07001 NTE family protein
AC611_00715	ENOG4105DKW	ABC transporter
AC611_00730	ENOG4108IJ8	ABC transporter
AC611_00735	ENOG4105E90	ABC transporter
AC611_00775	ENOG4105D1F	ATP-binding protein
AC611_00780	ENOG4105M4E	phosphohistidine phosphatase, SixA
AC611_00790	ENOG4107RZC	phospholipase d
AC611_00795	ENOG4105KA0	thioesterase Superfamily protein
AC611_00830	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
AC611_00835	ENOG4105C5F	glutamine synthetase
AC611_00845	ENOG4105BZU	Histidine kinase
AC611_00850	ENOG4105CUX	Signal transduction histidine kinase
AC611_00855	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AC611_00860	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
AC611_00865	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
AC611_00880	ENOG4105CHU	acetyl-coa acetyltransferase
AC611_00915	ENOG4107YZP	Rhodanese domain protein
AC611_00920	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
AC611_00925	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
AC611_00955	ENOG4108TQ9	Histidine kinase
AC611_00960	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AC611_00980	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
AC611_00995	ENOG4105E2T	synthase III
AC611_01000	ENOG4107R3N	Filamentation induced by cAMP protein fic
AC611_01005	ENOG4108J2P	Alpha beta hydrolase fold
AC611_01010	ENOG4105PI0	Ferredoxin
AC611_01015	ENOG410680H	amp-dependent synthetase and ligase
AC611_01020	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
AC611_01040	ENOG4105CPF	Cell wall formation (By similarity)
AC611_01055	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
AC611_01065	ENOG4105DR9	pseudouridine synthase
AC611_01075	ENOG4108YZN	class I peptide chain release factor
AC611_01085	ENOG4105D44	asparaginase
AC611_01090	ENOG4105DGW	oligopeptidase A
AC611_01130	ENOG4107QP3	malate synthase g
AC611_01140	ENOG4105BZU	Histidine kinase
AC611_01155	ENOG4105F2I	Transposase
AC611_01175	ENOG4107QX3	carboxylase
AC611_01180	ENOG4105C1G	acyl-Coa dehydrogenase
AC611_01250	ENOG4108TZV	Membrane
AC611_01260	ENOG4105D6Z	AFG1 family ATPase
AC611_01265	ENOG4105K56	Transcriptional regulator
AC611_01270	ENOG4108ZHJ	Organic hydroperoxide resistance protein
AC611_01290	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
AC611_01305	ENOG4108R99	pseudouridine synthase
AC611_01315	ENOG4105CQ7	ATP-dependent helicase
AC611_01320	ENOG4108W15	Protein of unknown function (DUF1456)
AC611_01325	ENOG4105VT2	5-hydroxyisourate hydrolase
AC611_01330	ENOG4105E1J	oxidoreductase
AC611_01350	ENOG4105C5R	Aminotransferase
AC611_01360	ENOG4105HEI	LysR family (Transcriptional regulator
AC611_01375	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
AC611_01385	ENOG4105DU0	nucleoside hydrolase
AC611_01395	ENOG4105C7N	Xanthine uracil vitamin C permease
AC611_01415	ENOG4105ETT	transcriptional Regulator, LysR family
AC611_01420	ENOG4105F8V	Hydrolase, tatD family
AC611_01435	ENOG4106NZI	LysR family Transcriptional regulator
AC611_01440	ENOG4105D94	Major Facilitator Superfamily
AC611_01455	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
AC611_01460	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
AC611_01480	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
AC611_01485	ENOG4105EB3	Histidine kinase
AC611_01490	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
AC611_01495	ENOG4105BZS	acriflavin resistance protein
AC611_01500	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
AC611_01515	ENOG4105WPN	DNA integration recombination invertion protein
AC611_01520	ENOG4105DZ2	Transcriptional regulator
AC611_01525	ENOG4108UZX	fmn reductase
AC611_01535	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
AC611_01540	ENOG4105CAX	The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity)
AC611_01560	ENOG4105ECR	NmrA family
AC611_01585	ENOG4105D5G	Transposase
AC611_01625	ENOG4105CMM	transposase
AC611_01635	ENOG4105C01	Dihydroxy-acid dehydratase
AC611_01655	ENOG4108Z0R	Transferase
AC611_01665	ENOG4105D2S	major facilitator superfamily
AC611_01670	ENOG4105CPI	Metal Dependent Phosphohydrolase
AC611_01700	ENOG41072AC	4-hydroxybenzoate 3-monooxygenase
AC611_01710	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
AC611_01715	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
AC611_01720	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
AC611_01725	ENOG4105E98	transcriptional regulator DeoR family
AC611_01750	ENOG4105CHU	acetyl-coa acetyltransferase
AC611_01765	ENOG4107RAW	3-carboxy-cis-cis-muconate cycloisomerase
AC611_01770	ENOG4105F2Z	3-oxoadipate enol-lactonase
AC611_01775	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
AC611_01785	ENOG4107HP6	Transcriptional regulator
AC611_01805	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
AC611_01845	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
AC611_01855	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
AC611_01860	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
AC611_01865	ENOG41081UC	Inherit from COG: Competence protein
AC611_01870	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
AC611_01890	ENOG4105F2I	Transposase
AC611_01930	ENOG4105VS8	Flagellar biosynthetic protein fliq
AC611_01950	ENOG4108HR8	type iii secretion
AC611_01970	ENOG4107Y59	type iii secretion
AC611_01985	ENOG4108JIR	Flagellum-specific ATP synthase
AC611_01995	ENOG4108TN6	type iii secretion
AC611_02000	ENOG4105K44	type iii secretion
AC611_02010	ENOG4105FTC	Lytic transglycosylase catalytic
AC611_02025	ENOG4105EGS	Mechanosensitive ion channel
AC611_02030	ENOG4107RES	phosphoglycerol transferase I
AC611_02040	ENOG4105CKW	Inner membrane protein yedI
AC611_02045	ENOG4105BZU	Histidine kinase
AC611_02050	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
AC611_02055	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
AC611_02060	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
AC611_02085	ENOG4105K4T	epimerase
AC611_02110	ENOG4105D5G	Transposase
AC611_02120	ENOG4105F2I	Transposase
AC611_02160	ENOG4105BZS	acriflavin resistance protein
AC611_02165	ENOG4105CHR	reductase
AC611_02175	ENOG4105C1J	atp-dependent rna helicase
AC611_02180	ENOG4105C7S	Dehydrogenase
AC611_02190	ENOG4105CPP	Dehydrogenase, E1 component
AC611_02195	ENOG4107RUY	(E1 component), alpha subunit
AC611_02205	ENOG4105HJ8	Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity)
AC611_02210	ENOG4105DUX	Transporter
AC611_02230	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
AC611_02235	ENOG4105F1J	Homogentisate 1,2-dioxygenase
AC611_02250	ENOG4105KJM	monovalent cation h antiporter subunit g
AC611_02255	ENOG4105W4C	monovalent cation H antiporter subunit F
AC611_02265	ENOG4107R4Z	monovalent cation h antiporter subunit d
AC611_02270	ENOG4108ZE9	Monovalent cation H antiporter subunit C
AC611_02275	ENOG4105D65	subunit l
AC611_02295	ENOG4105NVB	glycoside hydrolase, family 19
AC611_02315	ENOG4105C8V	SAICAR synthetase
AC611_02320	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
AC611_02340	ENOG4107TE5	Lipid kinase
AC611_02345	ENOG4105CRQ	synthase (Component I)
AC611_02355	ENOG4105DDQ	anthranilate synthase
AC611_02365	ENOG4108I0Q	anthranilate phosphoribosyltransferase
AC611_02370	ENOG4105DK0	Indole-3-glycerol phosphate synthase
AC611_02380	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
AC611_02385	ENOG4105FDS	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
AC611_02395	ENOG4108S0N	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol (By similarity)
AC611_02400	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
AC611_02405	ENOG4108UJD	30S ribosomal protein S9
AC611_02420	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
AC611_02430	ENOG4108UQY	Iron-storage protein
AC611_02435	ENOG4105BZU	Histidine kinase
AC611_02460	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
AC611_02475	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
AC611_02490	ENOG4108J8Q	Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity)
AC611_02505	ENOG4105EM2	membrane
AC611_02515	ENOG4105C12	Phosphoribosylglycinamide synthetase
AC611_02525	ENOG4105DC1	bifunctional purine biosynthesis protein purh
AC611_02530	ENOG4108UMZ	Cdp-alcohol phosphatidyltransferase
AC611_02535	ENOG4105E8V	Alpha Beta Hydrolase Fold protein
AC611_02540	ENOG41077RS	Phosphatase
AC611_02565	ENOG4108HPI	phosphatidate Cytidylyltransferase
AC611_02570	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
AC611_02595	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
AC611_02610	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
AC611_02620	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
AC611_02625	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
AC611_02635	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
AC611_02640	ENOG4105VF7	tolerance protein
AC611_02650	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
AC611_02670	ENOG4105EUP	HipA domain protein
AC611_02675	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
AC611_02705	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
AC611_02710	ENOG4105EX9	Membrane
AC611_02725	ENOG4105F2I	Transposase
AC611_02740	ENOG4108RDT	NADH dehydrogenase NAD(P)H nitroreductase)
AC611_02745	ENOG4108YYC	ycei family
AC611_02780	ENOG4105WSE	Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism (By similarity)
AC611_02795	ENOG41065ZS	Transfers 2'-(5-triphosphoribosyl)-3'-dephosphocoenzyme- A to the apo- acyl-carrier-protein of the malonate decarboxylase to yield holo- acyl-carrier-protein (By similarity)
AC611_02800	ENOG4108K6F	triphosphoribosyl-dephospho-CoA synthase
AC611_02805	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
AC611_02815	ENOG4105DRR	Transcriptional regulator, GntR family
AC611_02860	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
AC611_02865	ENOG4105D5G	Transposase
AC611_02875	ENOG4107GJV	short-chain dehydrogenase reductase
AC611_02900	ENOG4105PDP	Short chain dehydrogenase
AC611_02910	ENOG4105CHF	Glutathione S-transferase
AC611_02955	ENOG4107QS8	(LipO)protein
AC611_02960	ENOG4105BZU	Histidine kinase
AC611_02965	ENOG4108Z40	Transcriptional regulator
AC611_02990	ENOG4105DFI	Membrane
AC611_02995	ENOG4108YQE	rare lipoprotein a
AC611_03005	ENOG41065HY	1,4-beta-cellobiosidase
AC611_03020	ENOG4105C85	amino acid
AC611_03030	ENOG4105D7N	magnesium and cobalt transport protein CorA
AC611_03040	ENOG4105E53	ec 3.2.1.28
AC611_03080	ENOG4105BZU	Histidine kinase
AC611_03095	ENOG4106R7G	Glycoside hydrolase family 5
AC611_03125	ENOG4105C3A	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity)
AC611_03135	ENOG4108HRK	Histidine kinase
AC611_03140	ENOG4108NEV	two component transcriptional regulator, LytTR family
AC611_03145	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
AC611_03200	ENOG4105WD1	Membrane
AC611_03210	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
AC611_03220	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
AC611_03225	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
AC611_03230	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
AC611_03255	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
AC611_03260	ENOG4105BZU	Histidine kinase
AC611_03265	ENOG4105CD8	aminopeptidase N
AC611_03285	ENOG4105DZG	Dehydrogenase
AC611_03290	ENOG4108Q1J	Extracellular solute-binding protein, family 3
AC611_03315	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
AC611_03335	ENOG4105DFF	Rod shape-determining protein mreb
AC611_03340	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
AC611_03355	ENOG4105CNI	cell division protein FtsW
AC611_03365	ENOG4105F2I	Transposase
AC611_03385	ENOG4107WN4	Polygalacturonase
AC611_03390	ENOG4105CVE	Lytic murein transglycosylase
AC611_03395	ENOG4105K6T	rare lipoprotein A
AC611_03400	ENOG4105DZ1	carboxypeptidase
AC611_03415	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
AC611_03420	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
AC611_03425	ENOG4105CN1	protease
AC611_03435	ENOG4108KSA	LysR family transcriptional regulator
AC611_03480	ENOG4108J5G	6-phosphogluconate dehydrogenase
AC611_03485	ENOG4105D9R	oxidoreductase
AC611_03490	ENOG4105W4M	Transport-associated protein
AC611_03495	ENOG4105BZU	Histidine kinase
AC611_03505	ENOG4105BZU	Histidine kinase
AC611_03515	ENOG4105CHR	reductase
AC611_03555	ENOG4105GVR	general secretion pathway protein D
AC611_03560	ENOG4107QHF	type ii secretion system protein e
AC611_03565	ENOG4105D7Q	type ii secretion system
AC611_03570	ENOG4108VAU	general secretion pathway protein G
AC611_03575	ENOG4105VWV	general secretion pathway protein h
AC611_03580	ENOG4105X5Z	General secretion pathway protein I
AC611_03590	ENOG4108RTD	type II secretion system protein K
AC611_03610	ENOG4105FDP	GntR family transcriptional regulator
AC611_03620	ENOG4105ETE	Transcriptional regulator (LacI family
AC611_03625	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
AC611_03630	ENOG4105CE4	GlcNAc 6-P deacetylase
AC611_03640	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
AC611_03645	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
AC611_03655	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
AC611_03670	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
AC611_03680	ENOG4108K5H	permease YjgP YjgQ family protein
AC611_03695	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
AC611_03700	ENOG4105T95	Thiol disulfide interChange protein
AC611_03705	ENOG4108ETH	Formylglycinamide ribotide synthetase
AC611_03715	ENOG4105EUR	Domain-Containing protein
AC611_03720	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
AC611_03725	ENOG4105EUR	Domain-Containing protein
AC611_03730	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
AC611_03735	ENOG4107QHF	type ii secretion system protein e
AC611_03740	ENOG4105D7Q	type ii secretion system
AC611_03750	ENOG4105WMT	general secretion pathway protein h
AC611_03760	ENOG41069G9	General secretion pathway protein J
AC611_03765	ENOG4105UV2	general secretion pathway protein K
AC611_03770	ENOG41090VX	general secretion pathway protein L
AC611_03775	ENOG410678M	general secretion pathway protein M
AC611_03785	ENOG4105GVR	general secretion pathway protein D
AC611_03795	ENOG4106S9K	Transcriptional regulator
AC611_03855	ENOG4107RH7	Nicotinate phosphoribosyltransferase
AC611_03870	ENOG4107QZ7	Cellulose synthase catalytic subunit
AC611_03875	ENOG4107EEX	Cellulose synthase regulator protein
AC611_03880	ENOG4105K2Z	endo-1,4-d-glucanase (EC 3.2.1.4)
AC611_03910	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
AC611_03915	ENOG4105C5H	ABC transporter
AC611_03925	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
AC611_03930	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
AC611_03940	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
AC611_03950	ENOG4105D5G	Transposase
AC611_03965	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
AC611_03970	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
AC611_03975	ENOG4107YIM	Involved in the transcription termination process (By similarity)
AC611_03980	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
AC611_03995	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
AC611_04000	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
AC611_04010	ENOG4105C08	Histidine kinase
AC611_04015	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
AC611_04025	ENOG4105CQB	FAD linked oxidase domain protein
AC611_04030	ENOG4105S2T	inner membrane protein YbcI
AC611_04035	ENOG41082RQ	UPF0102 protein
AC611_04060	ENOG4108V6E	Cell division protein mraZ
AC611_04070	ENOG4106932	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
AC611_04075	ENOG4105CJN	penicillin-binding protein
AC611_04080	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
AC611_04085	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
AC611_04090	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
AC611_04100	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
AC611_04105	ENOG4105DFU	Cell wall formation (By similarity)
AC611_04110	ENOG4105CPF	Cell wall formation (By similarity)
AC611_04115	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
AC611_04120	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
AC611_04125	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
AC611_04130	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
AC611_04140	ENOG4105DR5	peptidase
AC611_04145	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
AC611_04150	ENOG4105M6F	mutator MutT protein
AC611_04160	ENOG4105SYT	Methylenetetrahydrofolate reductase
AC611_04225	ENOG4105DXX	methyltransferase
AC611_04230	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
AC611_04240	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
AC611_04260	ENOG4105UYK	outer membrane protein a
AC611_04275	ENOG4105D6F	Phosphatase
AC611_04280	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
AC611_04290	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
AC611_04295	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
AC611_04305	ENOG4108RVA	ribokinase
AC611_04310	ENOG4105D9N	nucleoside
AC611_04315	ENOG4105CPC	Aldo Keto reductase
AC611_04325	ENOG4105D05	Receptor
AC611_04345	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
AC611_04360	ENOG4105E2B	Taurine dioxygenase
AC611_04370	ENOG4108I0Y	(ABC) transporter
AC611_04375	ENOG4108UJV	acyl-CoA thioesterase i
AC611_04380	ENOG4105ETX	regulatoR
AC611_04385	ENOG4105DHQ	Histidine kinase
AC611_04395	ENOG41080IJ	Diacylglycerol kinase
AC611_04405	ENOG4105HA9	of methanol dehydrogenase type
AC611_04415	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
AC611_04420	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
AC611_04435	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
AC611_04440	ENOG4105NWN	ApaG protein
AC611_04450	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
AC611_04455	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
AC611_04460	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
AC611_04475	ENOG4108WBT	adenosyltransferase
AC611_04485	ENOG4105D0A	hydroxylase
AC611_04490	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
AC611_04525	ENOG4105DDW	LysR family Transcriptional regulator
AC611_04530	ENOG4105CEY	Amp-dependent synthetase and ligase
AC611_04540	ENOG4108D7R	p-hydroxycinnamoyl CoA hydratase lyase
AC611_04570	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
AC611_04595	ENOG4105DXC	membrane
AC611_04605	ENOG4105CX6	glutaminyL-tRNA synthetase
AC611_04620	ENOG4105BZU	Histidine kinase
AC611_04625	ENOG4105BZU	Histidine kinase
AC611_04630	ENOG4105WH1	Two component transcriptional regulator luxr family
AC611_04650	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
AC611_04655	ENOG4105NXH	GreA GreB family elongation factor
AC611_04660	ENOG4105C5Q	Transcriptional regulator
AC611_04675	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
AC611_04695	ENOG4105C2M	dna polymerase I
AC611_04750	ENOG4105CM2	brancheD-chain amino acid aminotransferase
AC611_04755	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
AC611_04760	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
AC611_04765	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
AC611_04770	ENOG4108Z66	YbaK ebsC protein
AC611_04790	ENOG4105CS1	NAD(P)H quinone oxidoreductase
AC611_04795	ENOG4107S2Z	UPF0761 membrane protein
AC611_04800	ENOG4107QX9	Thiol disulfide interChange protein
AC611_04815	ENOG4105CSR	polyphosphate kinase 2
AC611_04820	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
AC611_04830	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
AC611_04835	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
AC611_04840	ENOG4105DJQ	tetratricopeptide tpr_2 repeat protein
AC611_04845	ENOG4105QVB	outer membrane lipoprotein LolB
AC611_04850	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
AC611_04860	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
AC611_04865	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
AC611_04870	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
AC611_04875	ENOG4105C3G	gtp-binding protein
AC611_04895	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
AC611_04905	ENOG4105PM1	preprotein translocase subunit SecE
AC611_04910	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
AC611_04915	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
AC611_04920	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
AC611_04925	ENOG4108VZM	50s ribosomal protein L10
AC611_04930	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
AC611_04935	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AC611_04940	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AC611_04945	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
AC611_04950	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
AC611_04955	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
AC611_04960	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
AC611_04970	ENOG4105D5G	Transposase
AC611_04975	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
AC611_04980	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
AC611_04985	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
AC611_04990	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
AC611_04995	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AC611_05000	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
AC611_05005	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
AC611_05010	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
AC611_05015	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
AC611_05025	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
AC611_05030	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
AC611_05035	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
AC611_05040	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AC611_05045	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
AC611_05050	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
AC611_05055	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
AC611_05060	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
AC611_05065	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
AC611_05075	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
AC611_05080	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
AC611_05085	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AC611_05090	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
AC611_05095	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
AC611_05100	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AC611_05105	ENOG4108ZT0	50S ribosomal protein l17
AC611_05110	ENOG41080I0	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
AC611_05130	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
AC611_05140	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
AC611_05155	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
AC611_05160	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
AC611_05165	ENOG4108K3A	Glutathione S-transferase
AC611_05175	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
AC611_05180	ENOG4105CIS	alcohol dehydrogenase
AC611_05185	ENOG4105D5G	Transposase
AC611_05190	ENOG4105F2I	Transposase
AC611_05195	ENOG4105F37	PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6
AC611_05205	ENOG4108R99	pseudouridine synthase
AC611_05215	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
AC611_05220	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
AC611_05225	ENOG4108I5D	sulfate abc transporter
AC611_05235	ENOG4108IJ6	ABC transporter
AC611_05245	ENOG4105D5G	Transposase
AC611_05250	ENOG4105CPQ	Dehydrogenase
AC611_05260	ENOG4105HSS	phospholipase C
AC611_05270	ENOG4105CVJ	phosphoglycerate mutase
AC611_05280	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
AC611_05295	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
AC611_05300	ENOG4105ED9	Protein of unknown function (DUF455)
AC611_05315	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
AC611_05320	ENOG4105EYK	Phosphatidylglycerophosphatase B
AC611_05325	ENOG4105BZF	Glycosyl transferase (Group 1
AC611_05330	ENOG4105C9X	ppx gppa phosphatase
AC611_05335	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
AC611_05340	ENOG4105BZU	Histidine kinase
AC611_05345	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AC611_05350	ENOG4105ERG	peptidase m48, ste24p
AC611_05355	ENOG4105VW4	glutaredoxin 3
AC611_05365	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
AC611_05400	ENOG4105D5G	Transposase
AC611_05415	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
AC611_05420	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
AC611_05425	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
AC611_05455	ENOG4105EIN	peptidylprolyl cis-trans isomerase
AC611_05465	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
AC611_05475	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
AC611_05480	ENOG4107RZZ	dna polymerase iii epsilon subunit
AC611_05485	ENOG4108ZF3	Phosphatase
AC611_05500	ENOG4105DKP	glycosyl transferase, family 9
AC611_05505	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
AC611_05510	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
AC611_05515	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
AC611_05525	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
AC611_05530	ENOG4105M00	molybdopterin converting factor, subunit 1
AC611_05535	ENOG4108ZAF	Molybdopterin
AC611_05545	ENOG4107QMP	dna polymerase iii subunits gamma and tau
AC611_05550	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
AC611_05555	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
AC611_05560	ENOG4105K59	histidine triad (HIT) protein
AC611_05570	ENOG4105F8C	transglutaminase domain-containing protein
AC611_05580	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
AC611_05590	ENOG4108UHJ	MAF-like protein
AC611_05595	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
AC611_05600	ENOG4105VGS	50s ribosomal protein l32
AC611_05605	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
AC611_05615	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
AC611_05620	ENOG4105CHR	reductase
AC611_05625	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
AC611_05630	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
AC611_05640	ENOG4105HHA	aminodeoxychorismate lyase
AC611_05645	ENOG4107QRG	dna polymerase iii
AC611_05675	ENOG4108JU7	Transcriptional regulator
AC611_05680	ENOG4105CR4	methylisocitrate lyase
AC611_05685	ENOG4105BZN	citrate synthase
AC611_05690	ENOG4108I0Z	Aconitate hydratase
AC611_05700	ENOG4105C7F	AcnD-accessory protein PrpF
AC611_05715	ENOG4105DN3	alpha-2-macroglobulin domain protein
AC611_05735	ENOG4105CUX	Signal transduction histidine kinase
AC611_05740	ENOG4108JQB	penicillin-binding protein 1C
AC611_05765	ENOG4105M3Z	response regulator
AC611_05770	ENOG4107QJR	hflk protein
AC611_05775	ENOG4105EPW	hflc protein
AC611_05785	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
AC611_05790	ENOG4105CD8	aminopeptidase N
AC611_05800	ENOG4105F6U	Short-chain dehydrogenase reductase Sdr
AC611_05805	ENOG4108XFH	Transcriptional regulator
AC611_05855	ENOG4107Z4K	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
AC611_05865	ENOG4105BZP	glycoside hydrolase 15-related
AC611_05875	ENOG4105CWX	Alpha-1,2-mannosidase
AC611_05900	ENOG4105C3M	thioredoxin reductase
AC611_05935	ENOG4105C7W	Xanthine dehydrogenase
AC611_05940	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
AC611_05945	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
AC611_05980	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
AC611_06000	ENOG4105C0B	DNA polymerase III (alpha subunit)
AC611_06015	ENOG4105EPD	Oligopeptide transporter, Opt family
AC611_06040	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
AC611_06060	ENOG4106AXJ	AraC family transcriptional regulator
AC611_06075	ENOG4105D5G	Transposase
AC611_06090	ENOG4105CV8	reductase
AC611_06095	ENOG4105EBR	Carboxylesterase
AC611_06100	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AC611_06120	ENOG4108JJA	ABC, transporter
AC611_06125	ENOG4105C2C	drug resistance transporter, Bcr CflA
AC611_06165	ENOG4105DIJ	Phosphoethanolamine transferase
AC611_06180	ENOG4105ETX	regulatoR
AC611_06185	ENOG4105DHQ	Histidine kinase
AC611_06195	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
AC611_06200	ENOG4107QMS	site-determining protein
AC611_06205	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
AC611_06215	ENOG4105BZU	Histidine kinase
AC611_06220	ENOG4105WH1	Two component transcriptional regulator luxr family
AC611_06265	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
AC611_06275	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
AC611_06290	ENOG4105GFR	rna polymerase sigma factor
AC611_06300	ENOG4105C29	acyl-CoA thioesterase
AC611_06315	ENOG4108TGP	Thioesterase superfamily protein
AC611_06320	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
AC611_06325	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
AC611_06330	ENOG4105K46	50S ribosomal protein l27
AC611_06335	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AC611_06340	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
AC611_06345	ENOG4105CJR	Integral membrane protein (MviN
AC611_06350	ENOG4105DTN	riboflavin biosynthesis protein ribF
AC611_06355	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
AC611_06360	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
AC611_06365	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
AC611_06505	ENOG4105E2S	oxidase) subunit II
AC611_06510	ENOG4105BZ9	Cytochrome C oxidase, subunit I
AC611_06515	ENOG4105CCU	oxidase (Subunit III)
AC611_06520	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
AC611_06530	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
AC611_06535	ENOG4105KAF	membrAne
AC611_06550	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
AC611_06560	ENOG4107MMM	Anti-sigma-factor antagonist
AC611_06565	ENOG4105FUA	antagonist
AC611_06580	ENOG4105BZU	Histidine kinase
AC611_06605	ENOG4105KCV	RNA signal recognition particle 4.5S RNA
AC611_06610	ENOG4105C08	Histidine kinase
AC611_06615	ENOG4107Z5C	methylesterase
AC611_06620	ENOG4105BZU	Histidine kinase
AC611_06625	ENOG4105BZU	Histidine kinase
AC611_06640	ENOG4105CZZ	Alpha-N-arabinofuranosidase (EC 3.2.1.55)
AC611_06650	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
AC611_06660	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AC611_06670	ENOG4107QWG	2-Nitropropane dioxygenase
AC611_06675	ENOG4105CM2	brancheD-chain amino acid aminotransferase
AC611_06680	ENOG4105K5M	30s ribosomal protein S16
AC611_06685	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
AC611_06690	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
AC611_06695	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
AC611_06700	ENOG4107QJQ	Mate efflux family protein
AC611_06720	ENOG4105VEJ	Heat shock protein
AC611_06725	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
AC611_06735	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
AC611_06755	ENOG4105CMM	transposase
AC611_06760	ENOG4105CMM	transposase
AC611_06785	ENOG4105CNT	hydrolase family 2
AC611_06790	ENOG4106FKC	arabinogalactan endo-1,4-beta-galactosidase
AC611_06805	ENOG4105C26	Dehydrogenase
AC611_06810	ENOG4105C1G	acyl-Coa dehydrogenase
AC611_06820	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
AC611_06825	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
AC611_06840	ENOG4107RDJ	Sulfotransferase
AC611_06850	ENOG4107RDJ	Sulfotransferase
AC611_06860	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
AC611_06865	ENOG4105EMN	RNA polymerase sigma factor
AC611_06875	ENOG4105C0H	protease
AC611_06880	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
AC611_06885	ENOG4105C3F	Signal peptidase i
AC611_06895	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
AC611_06900	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
AC611_06905	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
AC611_06915	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
AC611_06920	ENOG41080ZE	Adenylate cyclase
AC611_06925	ENOG4107ZXU	DSBA oxidoreductase
AC611_06930	ENOG4108QDE	fad dependent oxidoreductase
AC611_06935	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
AC611_06940	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
AC611_06945	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
AC611_06950	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
AC611_06955	ENOG4105VEQ	Cold shock protein
AC611_06960	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
AC611_06970	ENOG4107QRT	dEAD DEAH box helicase
AC611_06975	ENOG4107T0X	DNA ligase
AC611_06985	ENOG4107T0X	DNA ligase
AC611_07000	ENOG4105BZU	Histidine kinase
AC611_07015	ENOG4105CHU	acetyl-coa acetyltransferase
AC611_07035	ENOG4108VKG	metal-dependent hydrolase
AC611_07050	ENOG4105KSC	Transcriptional regulator, TraR DksA family
AC611_07075	ENOG4108YZY	peptidylprolyl cis-trans isomerase
AC611_07085	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
AC611_07095	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
AC611_07100	ENOG4105F27	Major Facilitator
AC611_07145	ENOG4105M4H	endoribonuclease L-psp
AC611_07150	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
AC611_07165	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
AC611_07190	ENOG4105K6V	RNA polymerase
AC611_07210	ENOG4108R3D	Electron transport complex
AC611_07220	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
AC611_07240	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
AC611_07255	ENOG4108IQI	permease
AC611_07260	ENOG4107QK5	Homocysteine s-methyltransferase
AC611_07310	ENOG4108YXA	Membrane
AC611_07325	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
AC611_07340	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
AC611_07345	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
AC611_07350	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
AC611_07355	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
AC611_07370	ENOG4105DZP	Membrane-associated zinc metalloprotease
AC611_07375	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
AC611_07380	ENOG4105KNE	Phosphatidate cytidylyltransferase
AC611_07385	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
AC611_07390	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
AC611_07395	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
AC611_07400	ENOG4105BZU	Histidine kinase
AC611_07405	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
AC611_07410	ENOG4105CE9	30S ribosomal protein S2
AC611_07445	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
AC611_07450	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
AC611_07460	ENOG4105KUZ	arsenate reductase
AC611_07465	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
AC611_07470	ENOG4105CAQ	asparagine synthetase
AC611_07485	ENOG4108ESX	Receptor
AC611_07495	ENOG4108UWD	Iron-storage protein
AC611_07515	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AC611_07540	ENOG4105D5G	Transposase
AC611_07575	ENOG4105CW7	secretion protein, HlyD family
AC611_07580	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
AC611_07610	ENOG4105DUX	Transporter
AC611_07640	ENOG4105DGW	oligopeptidase A
AC611_07645	ENOG4108V06	Glutathione peroxidase
AC611_07650	ENOG4105DP0	ferredoxin-NADP reductase
AC611_07660	ENOG4107GFK	fumarate
AC611_07680	ENOG4105HDD	phospholipase
AC611_07690	ENOG4105VEQ	Cold shock protein
AC611_07705	ENOG4105CUZ	uba thif-type nad fad binding protein
AC611_07710	ENOG4105EYA	deoxyribonuclease
AC611_07725	ENOG4105C1G	acyl-Coa dehydrogenase
AC611_07735	ENOG4108RXX	maleylacetoacetate isomerase
AC611_07740	ENOG4105CAQ	asparagine synthetase
AC611_07750	ENOG4105CDU	Replicative dna helicase
AC611_07755	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
AC611_07760	ENOG4105CDV	Ompa motb domain protein
AC611_07765	ENOG4105CR8	Transcriptional regulator
AC611_07800	ENOG4105BZU	Histidine kinase
AC611_07810	ENOG4106TD9	Diguanylate cyclase
AC611_07830	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
AC611_07835	ENOG4108Z1B	Cyclase dehydrase
AC611_07845	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
AC611_07850	ENOG41090R7	Ferric uptake
AC611_07855	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
AC611_07860	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
AC611_07865	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AC611_07870	ENOG4105CFG	Acts as a chaperone (By similarity)
AC611_07875	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
AC611_07910	ENOG4105C5Q	Transcriptional regulator
AC611_07915	ENOG4105BZ1	(ABC) transporter
AC611_07925	ENOG4108URH	decarboxylase
AC611_07935	ENOG4105C7S	Dehydrogenase
AC611_07940	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
AC611_07950	ENOG4105EZE	Cupin 4 family protein
AC611_07960	ENOG4107QTF	adenylosuccinate lyase
AC611_07970	ENOG4105C37	(CBS) domain
AC611_08000	ENOG4105CZV	ABC transporter
AC611_08005	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
AC611_08015	ENOG4108V1T	peptidylprolyl cis-trans isomerase
AC611_08020	ENOG41069P5	Protein slyX homolog
AC611_08035	ENOG4105ETE	Transcriptional regulator (LacI family
AC611_08045	ENOG4105D7K	pfkb domain protein
AC611_08055	ENOG4105C3R	Methionine synthase
AC611_08060	ENOG4105C3R	Methionine synthase
AC611_08070	ENOG4105C1G	acyl-Coa dehydrogenase
AC611_08085	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
AC611_08095	ENOG4105C2N	RNA methyltransferase TrmH family group 3
AC611_08110	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
AC611_08120	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
AC611_08125	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
AC611_08130	ENOG4105E2Z	phosphate ABC transporter (Permease
AC611_08135	ENOG4105C8U	phosphate abc transporter
AC611_08140	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
AC611_08160	ENOG4107B2H	carbonic anhydrase
AC611_08165	ENOG4105CHH	sulfate transporter
AC611_08170	ENOG4105CSM	endonuclease III
AC611_08180	ENOG4105E39	Enoyl-CoA hydratase
AC611_08185	ENOG4108V1T	peptidylprolyl cis-trans isomerase
AC611_08190	ENOG4105P8F	nudix hydrolase
AC611_08195	ENOG4105KHC	sulfurtransferase
AC611_08225	ENOG4105C5H	ABC transporter
AC611_08235	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
AC611_08240	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
AC611_08260	ENOG4105CJB	Exodeoxyribonuclease I
AC611_08265	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
AC611_08270	ENOG4105CKY	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively (By similarity)
AC611_08280	ENOG4105C3W	Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate (By similarity)
AC611_08285	ENOG41077A9	carbonic anhydrase
AC611_08330	ENOG4105WH1	Two component transcriptional regulator luxr family
AC611_08360	ENOG4105C5S	asparaginyl-tRNA synthetase
AC611_08365	ENOG4108Z4V	iron-sulfur cluster assembly
AC611_08370	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
AC611_08375	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
AC611_08380	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
AC611_08390	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
AC611_08400	ENOG4105CIH	Imidazole acetol-phosphate transaminase
AC611_08405	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
AC611_08410	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
AC611_08420	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
AC611_08425	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AC611_08430	ENOG4105DZG	Dehydrogenase
AC611_08440	ENOG4105CGP	Urocanate hydratase
AC611_08455	ENOG4105C84	Histidine ammonia-lyase
AC611_08460	ENOG4105CI2	imidazolone-5-propionate hydrolase
AC611_08500	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
AC611_08505	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
AC611_08510	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
AC611_08520	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
AC611_08535	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
AC611_08540	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
AC611_08545	ENOG4105CC0	LysR family Transcriptional regulator
AC611_08610	ENOG4105CQZ	Histidine kinase
AC611_08635	ENOG4105KWW	Biogenesis protein
AC611_08640	ENOG4107QX9	Thiol disulfide interChange protein
AC611_08645	ENOG4105DA4	cytochrome c-type biogenesis protein
AC611_08650	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
AC611_08660	ENOG41060IM	Heme exporter protein
AC611_08675	ENOG4105EMN	RNA polymerase sigma factor
AC611_08725	ENOG4105EGZ	biosynthesis protein
AC611_08755	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
AC611_08780	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
AC611_08790	ENOG41079KZ	Major Facilitator Superfamily
AC611_08795	ENOG4105DEN	Luciferase family
AC611_08820	ENOG4105CJ3	phosphate transporter
AC611_08835	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AC611_08845	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
AC611_08850	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
AC611_08860	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
AC611_08865	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
AC611_08875	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
AC611_08880	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
AC611_08885	ENOG4108DG9	Smr protein MutS2
AC611_08890	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
AC611_08895	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
AC611_08900	ENOG4108UM1	dedA family
AC611_08905	ENOG4108K5P	(LipO)protein
AC611_08910	ENOG4108UIV	Protein of unknown function (DUF498/DUF598)
AC611_08915	ENOG4105HBR	Rna-binding protein
AC611_08920	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
AC611_08925	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
AC611_08930	ENOG4105EEI	dihydropteroate synthase
AC611_08935	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
AC611_08940	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
AC611_08945	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
AC611_08950	ENOG4107TH8	cina domain protein
AC611_08955	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
AC611_08960	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
AC611_08965	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
AC611_08970	ENOG4105Y3E	Modulates RecA activity (By similarity)
AC611_08975	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
AC611_08980	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
AC611_08990	ENOG4107SDU	Methyl-accepting chemotaxis
AC611_09005	ENOG4105CWB	LysR family transcriptional Regulator
AC611_09045	ENOG4108IAB	Phoh family
AC611_09050	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AC611_09065	ENOG4107TUS	Dihydrodipicolinate synthase
AC611_09075	ENOG4108Z4U	Ferredoxin
AC611_09080	ENOG4105EI3	2-dehydro-3-deoxygalactonokinase EC 2.7.1.58
AC611_09090	ENOG4105CXK	mandelate racemase muconate lactonizing
AC611_09095	ENOG4108RTU	Aldolase
AC611_09145	ENOG4105CMG	Carbohydrate kinase
AC611_09150	ENOG4105C93	Xylose Isomerase
AC611_09165	ENOG4105D5G	Transposase
AC611_09180	ENOG4108KNB	n-acetylmuramoyl-l-alanine amidase
AC611_09185	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
AC611_09200	ENOG4105DJ0	Poly(A) Polymerase
AC611_09205	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AC611_09210	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
AC611_09215	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
AC611_09220	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
AC611_09225	ENOG4107QP8	phosphohexose isomerase
AC611_09265	ENOG4105KU2	hydrolase family 5
AC611_09270	ENOG4108UYB	regulatoR
AC611_09280	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
AC611_09285	ENOG410841Q	phosphoesterase PA-phosphatase related protein
AC611_09290	ENOG4105CSH	Transporter
AC611_09300	ENOG4108SXK	Transporter Drug Metabolite Exporter family
AC611_09305	ENOG4105D4A	Cell wall formation (By similarity)
AC611_09310	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
AC611_09325	ENOG4105C26	Dehydrogenase
AC611_09340	ENOG4105D5G	Transposase
AC611_09345	ENOG4105D5G	Transposase
AC611_09350	ENOG4105CG3	alpha amylase, catalytic region
AC611_09385	ENOG4105ETE	Transcriptional regulator (LacI family
AC611_09390	ENOG4105C22	threonyL-tRNA synthetase
AC611_09395	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
AC611_09400	ENOG41082NX	50s ribosomal protein l35
AC611_09405	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
AC611_09410	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
AC611_09415	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
AC611_09420	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
AC611_09425	ENOG4105WJX	transcriptional regulator MERR family
AC611_09445	ENOG4105D3Q	Sugar transferase
AC611_09470	ENOG4107Y2G	Glycosyl transferase (Group 1
AC611_09480	ENOG4108NQK	Catalyzes the transfer of a glucuronic acid (GlcA) residue from UDP-glucuronate to mannose-alpha-1,3-glucose-beta- 1,4-glucose-P-P-polyisoprenyl to form the lipid-linked tetrasaccharide GlcA-Man-Glc(2)-PP-Pol, with a glucuronic acid- beta-mannose linkage. Is involved in the biosynthesis of the exopolysaccharide xanthan, since it catalyzes the fourth glycosylation step in the assembly of the pentasaccharide-P-P- polyisoprenyl repeating unit of xanthan. Is unable to use the trisaccharide acceptor freed from the pyrophosphate lipid moiety. Does not show specificity for the lipidic portion of the acceptor. Shows diminished activity when tested with 6-O-acetyl-mannose- alpha-1,3-glucose-beta-1,4-glucose-P-P-polyisoprenyl, a
AC611_09505	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
AC611_09515	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
AC611_09535	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
AC611_09545	ENOG4105CSU	acyl-Coa dehydrogenase
AC611_09555	ENOG4105QNF	Outer membrane lipoprotein
AC611_09570	ENOG4105DKD	Incises the DNA at the 3' side of a lesion during nucleotide excision repair. Incises the DNA farther away from the lesion than UvrC. Not able to incise the 5' site of a lesion. When a lesion remains because UvrC is not able to induce the 3' incision, Cho incises the DNA. Then UvrC makes the 5' incision. The combined action of Cho and UvrC broadens the substrate range of nucleotide excision repair (By similarity)
AC611_09585	ENOG4105CQZ	Histidine kinase
AC611_09605	ENOG4105CEN	a g-specific adenine glycosylase
AC611_09610	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
AC611_09620	ENOG4105CTU	Proline racemase
AC611_09625	ENOG41080HI	glycine oxidase
AC611_09640	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
AC611_09650	ENOG4105DC7	peptidase M24
AC611_09665	ENOG4107QTZ	amino acid
AC611_09780	ENOG4105D5G	Transposase
AC611_09825	ENOG4105D5G	Transposase
AC611_09835	ENOG4105CMM	transposase
AC611_09845	ENOG4105KAV	tspo and mbr like protein
AC611_09850	ENOG4105D5G	Transposase
AC611_09855	ENOG4105CFH	Aspartokinase
AC611_09870	ENOG4105R0I	Feruloyl esterase
AC611_09890	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
AC611_09895	ENOG4105CUT	histidyl-tRNA synthetase
AC611_09910	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
AC611_09915	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
AC611_09920	ENOG4105CIH	Imidazole acetol-phosphate transaminase
AC611_09925	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
AC611_09930	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
AC611_09935	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
AC611_09940	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
AC611_09945	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
AC611_09960	ENOG4106YVY	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) (By similarity)
AC611_09965	ENOG4108CAF	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity)
AC611_09970	ENOG4107QY0	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity)
AC611_09975	ENOG4105CUB	amino acid
AC611_09980	ENOG4105CUB	amino acid
AC611_09990	ENOG4108JQ1	Dehydrogenase
AC611_09995	ENOG4105CQB	FAD linked oxidase domain protein
AC611_10015	ENOG4105FUQ	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
AC611_10025	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
AC611_10045	ENOG4105CE1	Ferrous iron transport protein b
AC611_10060	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
AC611_10065	ENOG4108RPX	mosc domain containing protein
AC611_10070	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
AC611_10075	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
AC611_10085	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
AC611_10090	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
AC611_10100	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
AC611_10115	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
AC611_10120	ENOG4105CRK	lysyL-tRNA synthetase
AC611_10125	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
AC611_10130	ENOG4105BZU	Histidine kinase
AC611_10135	ENOG4105BZU	Histidine kinase
AC611_10140	ENOG4105E39	Enoyl-CoA hydratase
AC611_10145	ENOG4105CEY	Amp-dependent synthetase and ligase
AC611_10160	ENOG4107QM5	aconitate hydratase
AC611_10175	ENOG4107QIJ	Aconitate hydratase 2
AC611_10180	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
AC611_10185	ENOG4105BZU	Histidine kinase
AC611_10190	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
AC611_10195	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
AC611_10200	ENOG4105BZU	Histidine kinase
AC611_10205	ENOG4105C8Q	Methyl-accepting chemotaxis
AC611_10215	ENOG4108V3W	Chemotaxis protein, CheW
AC611_10225	ENOG4105C8Q	Methyl-accepting chemotaxis
AC611_10230	ENOG4105C8Q	Methyl-accepting chemotaxis
AC611_10235	ENOG4105C8Q	Methyl-accepting chemotaxis
AC611_10240	ENOG4105C8Q	Methyl-accepting chemotaxis
AC611_10245	ENOG4105C8Q	Methyl-accepting chemotaxis
AC611_10255	ENOG4105C8Q	Methyl-accepting chemotaxis
AC611_10260	ENOG4105C8Q	Methyl-accepting chemotaxis
AC611_10270	ENOG4105C8Q	Methyl-accepting chemotaxis
AC611_10280	ENOG4105C8Q	Methyl-accepting chemotaxis
AC611_10285	ENOG4105C8Q	Methyl-accepting chemotaxis
AC611_10295	ENOG4105C8Q	Methyl-accepting chemotaxis
AC611_10300	ENOG4105C8Q	Methyl-accepting chemotaxis
AC611_10305	ENOG4105CBS	Chea signal transduction histidine kinase
AC611_10310	ENOG4108VYJ	response regulator receiver protein
AC611_10320	ENOG4108V3W	Chemotaxis protein, CheW
AC611_10325	ENOG4107QJE	Chromosome Partitioning Protein
AC611_10330	ENOG4105ER2	Ompa motb domain protein
AC611_10335	ENOG4105E14	MotA TolQ exbB proton channel
AC611_10375	ENOG4105CBS	Chea signal transduction histidine kinase
AC611_10385	ENOG4108VYJ	response regulator receiver protein
AC611_10390	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AC611_10395	ENOG4107R21	site-determining protein
AC611_10400	ENOG4105FZW	flagellar biosynthesis regulator FlhF
AC611_10405	ENOG4105D7B	Flagellar biosynthesis protein flha
AC611_10410	ENOG4105D00	flagellar biosynthetic protein flhB
AC611_10415	ENOG4105BZU	Histidine kinase
AC611_10425	ENOG4105F2I	Transposase
AC611_10435	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
AC611_10440	ENOG4105VS8	Flagellar biosynthetic protein fliq
AC611_10445	ENOG4105F2I	Transposase
AC611_10450	ENOG4105CN7	Flagellar biosynthetic protein FliP
AC611_10455	ENOG4105K0P	flagellar biosynthesis protein
AC611_10460	ENOG4105DD5	Flagellar motor switch protein
AC611_10465	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
AC611_10485	ENOG4108JIR	Flagellum-specific ATP synthase
AC611_10495	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
AC611_10500	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
AC611_10505	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
AC611_10510	ENOG4107RGC	Glycosyl transferase, family 2
AC611_10530	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
AC611_10545	ENOG4105D5G	Transposase
AC611_10580	ENOG4108P1X	synthase
AC611_10595	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AC611_10600	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
AC611_10605	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AC611_10625	ENOG4105MQ3	flagellar protein FliS
AC611_10630	ENOG4107W9T	flagellar hook-associated
AC611_10640	ENOG4105F2I	Transposase
AC611_10645	ENOG4105DTJ	flagellar hook-associated protein
AC611_10655	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
AC611_10660	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
AC611_10665	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
AC611_10670	ENOG4105CGA	flagellar basal-body rod protein FlgG
AC611_10685	ENOG4108KPB	Flagellar basal-body rod protein FlgF
AC611_10690	ENOG4105BZE	flagellar hook protein, FlgE
AC611_10695	ENOG410822I	Flagellar hook capping protein
AC611_10700	ENOG4108ZC9	flagellar basal-body rod protein flgc
AC611_10710	ENOG4107R88	Chemotaxis protein (CheV)
AC611_10735	ENOG4105BZU	Histidine kinase
AC611_10740	ENOG4105BZU	Histidine kinase
AC611_10745	ENOG4105BZU	Histidine kinase
AC611_10750	ENOG4105BZU	Histidine kinase
AC611_10770	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
AC611_10780	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
AC611_10785	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
AC611_10790	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
AC611_10795	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
AC611_10805	ENOG4105C3M	thioredoxin reductase
AC611_10810	ENOG4105CNU	cell division protein FtsK
AC611_10820	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
AC611_10830	ENOG4105D1H	recombination factor protein RarA
AC611_10835	ENOG41082MI	Protein CrcB homolog
AC611_10840	ENOG4105CHU	acetyl-coa acetyltransferase
AC611_10855	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
AC611_10860	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
AC611_10870	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
AC611_10880	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
AC611_10885	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
AC611_10890	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
AC611_10895	ENOG4105D06	uba thif-type nad fad binding protein
AC611_10930	ENOG4105CGK	Exodeoxyribonuclease III
AC611_10940	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
AC611_10945	ENOG41085AN	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
AC611_10965	ENOG4105H3G	oxidoreductase
AC611_10970	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
AC611_10980	ENOG4105I5W	Transporter
AC611_10990	ENOG4108IFG	nitrite reductase, (NAD(P)H)
AC611_11005	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
AC611_11015	ENOG4108N8X	transition metal ion binding
AC611_11045	ENOG4108ZXC	Two component transcriptional regulator, luxr family
AC611_11095	ENOG4105D5G	Transposase
AC611_11105	ENOG4105F2I	Transposase
AC611_11110	ENOG4105D5G	Transposase
AC611_11175	ENOG4105D5G	Transposase
AC611_11185	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
AC611_11200	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
AC611_11220	ENOG4105D5G	Transposase
AC611_11295	ENOG4105D5G	Transposase
AC611_11305	ENOG4107SKI	cobyrinic Acid a,c-diamide synthase
AC611_11350	ENOG4106RHG	Yeca family
AC611_11390	ENOG4105D5G	Transposase
AC611_11420	ENOG4105MKU	Transcriptional regulator
AC611_11435	ENOG41090A4	Pterin carbinolamine dehydratase
AC611_11445	ENOG4105DUN	Mediates zinc uptake. May also transport other divalent cations (By similarity)
AC611_11450	ENOG4108NST	exported protein
AC611_11455	ENOG4105EI2	Pseudouridine synthase
AC611_11460	ENOG4105C03	ribonuclease
AC611_11465	ENOG4105F2I	Transposase
AC611_11475	ENOG4105C72	UPF0176 protein
AC611_11485	ENOG4108V1T	peptidylprolyl cis-trans isomerase
AC611_11495	ENOG4107QQG	Dehydrogenase
AC611_11520	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
AC611_11525	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
AC611_11540	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
AC611_11545	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
AC611_11550	ENOG4105BZ1	(ABC) transporter
AC611_11565	ENOG4108EC8	DNA internalization-related competence protein ComEC
AC611_11575	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
AC611_11580	ENOG4105D60	lipoprotein releasing system transmembrane protein
AC611_11590	ENOG410681N	tpr repeat protein
AC611_11615	ENOG410612Q	succinate dehydrogenase (cytochrome b-556 subunit)
AC611_11620	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
AC611_11635	ENOG4105CHC	glucokinase (EC 2.7.1.2)
AC611_11640	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
AC611_11645	ENOG4105C01	Dihydroxy-acid dehydratase
AC611_11650	ENOG4108UHU	Aldolase
AC611_11675	ENOG4105N7H	Cytochrome
AC611_11720	ENOG4105BZU	Histidine kinase
AC611_11725	ENOG4105BZM	domain protein
AC611_11750	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
AC611_11760	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
AC611_11780	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
AC611_11795	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
AC611_11800	ENOG4108Z6B	deaminase
AC611_11805	ENOG4105KST	dependent repressor
AC611_11810	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
AC611_11830	ENOG4107SFI	Major Facilitator superfamily
AC611_11845	ENOG4105CHJ	isochorismatase hydrolase
AC611_11865	ENOG4105WH1	Two component transcriptional regulator luxr family
AC611_11900	ENOG4105DND	Transcriptional regulator
AC611_11910	ENOG4105EVH	UPF0753 protein
AC611_11920	ENOG4105CB2	alcohol dehydrogenase
AC611_11925	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
AC611_11985	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
AC611_11990	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
AC611_11995	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
AC611_12005	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
AC611_12010	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
AC611_12020	ENOG4105ESV	Glycosyl transferase, family 4
AC611_12025	ENOG4105CFV	Tetratricopeptide repeat protein
AC611_12035	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
AC611_12040	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
AC611_12045	ENOG4105CAT	Cytidine monophosphate kinase
AC611_12050	ENOG4105YK5	50S ribosomal protein L36
AC611_12060	ENOG4105DWY	Agmatine deiminase
AC611_12090	ENOG4105DRS	transport system, permease
AC611_12095	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
AC611_12130	ENOG4105K9H	YciI-like protein
AC611_12135	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
AC611_12140	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
AC611_12145	ENOG4105FE9	pseudouridine synthase
AC611_12160	ENOG4105CZ7	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
AC611_12165	ENOG4105CHM	Aminotransferase
AC611_12170	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
AC611_12175	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
AC611_12180	ENOG41060IM	Heme exporter protein
AC611_12190	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
AC611_12195	ENOG4105DA4	cytochrome c-type biogenesis protein
AC611_12205	ENOG4105KWW	Biogenesis protein
AC611_12210	ENOG4108M1T	Cytochrome c-type biogenesis protein
AC611_12215	ENOG4105DWV	Homoserine O-trans-acetylase
AC611_12225	ENOG4108JJ8	(ABC) transporter
AC611_12230	ENOG4108JJ9	ABC, transporter
AC611_12235	ENOG4105C4M	(Ubiquinol oxidase) subunit I
AC611_12240	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
AC611_12270	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
AC611_12275	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
AC611_12285	ENOG4105CH7	arginosuccinase
AC611_12290	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
AC611_12300	ENOG4105CAS	nag kinase
AC611_12315	ENOG4105CDH	Citrulline--aspartate ligase
AC611_12320	ENOG4105DBV	ornithine carbamoyltransferase
AC611_12330	ENOG4105C8N	cysteinyl-tRNA synthetase
AC611_12335	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
AC611_12345	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AC611_12355	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
AC611_12360	ENOG4105CD3	dihydroorotase
AC611_12380	ENOG4105CPD	ethanolamine ammonia-lyase
AC611_12385	ENOG4107FQ9	ethanolamine ammonia-lyase
AC611_12410	ENOG4105F2I	Transposase
AC611_12435	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
AC611_12440	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
AC611_12445	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
AC611_12455	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
AC611_12460	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
AC611_12465	ENOG4105BZU	Histidine kinase
AC611_12480	ENOG4105ECY	inositol monophosphatase
AC611_12485	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
AC611_12500	ENOG4105C5H	ABC transporter
AC611_12505	ENOG4105C1J	atp-dependent rna helicase
AC611_12510	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
AC611_12515	ENOG4105CNG	UPF0061 protein
AC611_12535	ENOG4108RXX	maleylacetoacetate isomerase
AC611_12540	ENOG4105VEQ	Cold shock protein
AC611_12545	ENOG4108VWS	Yaeq family
AC611_12550	ENOG4105CBX	hi0933 family
AC611_12560	ENOG4105D0M	Protease HtpX homolog
AC611_12565	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
AC611_12570	ENOG4105CHR	reductase
AC611_12590	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
AC611_12595	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
AC611_12600	ENOG4105K8N	protein family UPF0079, ATPase
AC611_12605	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
AC611_12610	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
AC611_12615	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
AC611_12625	ENOG4105E6M	Sulphatase-modifying factor protein
AC611_12635	ENOG4105DQE	DNA ligase
AC611_12665	ENOG4108V3W	Chemotaxis protein, CheW
AC611_12670	ENOG4105C8Q	Methyl-accepting chemotaxis
AC611_12675	ENOG4108VX5	3-methyladenine DNA glycosylase
AC611_12680	ENOG4107QRT	dEAD DEAH box helicase
AC611_12695	ENOG4105KB2	stringent starvation protein b
AC611_12700	ENOG4107MKT	Stringent starvation protein a
AC611_12705	ENOG4105EIX	cytochrome c1
AC611_12710	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
AC611_12715	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
AC611_12725	ENOG4105E4C	Lytic transglycosylase catalytic
AC611_12740	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
AC611_12745	ENOG4105C9A	Phoh family
AC611_12755	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
AC611_12765	ENOG4108JU5	Magnesium and cobalt efflux protein
AC611_12790	ENOG4105D38	putrescine abc transporter
AC611_12795	ENOG4105F38	ABC transporter, permease
AC611_12800	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
AC611_12820	ENOG4107RUE	extracellular solute-binding protein family 1
AC611_12825	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
AC611_12840	ENOG4105CFQ	glutamine synthetase
AC611_12845	ENOG4105CJP	fad dependent oxidoreductase
AC611_12850	ENOG4105BZU	Histidine kinase
AC611_12855	ENOG4105W3S	hemerythrin-like, metal-binding protein
AC611_12860	ENOG4105CSH	Transporter
AC611_12870	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
AC611_12875	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
AC611_12880	ENOG4105FCD	Major Facilitator
AC611_12885	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
AC611_12895	ENOG4106BRA	Membrane
AC611_12900	ENOG4105BZU	Histidine kinase
AC611_12905	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
AC611_12910	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
AC611_12915	ENOG4105C8Q	Methyl-accepting chemotaxis
AC611_12945	ENOG4105C7I	Dehydrogenase
AC611_12955	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
AC611_12960	ENOG4105BZS	acriflavin resistance protein
AC611_12965	ENOG4108M60	Transcriptional regulator
AC611_12970	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
AC611_12975	ENOG4105DE4	1-phosphofructokinase
AC611_12980	ENOG4105DM4	PTS System
AC611_12995	ENOG4105D5G	Transposase
AC611_13000	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
AC611_13005	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
AC611_13010	ENOG4105VIE	preprotein translocase, subunit YajC
AC611_13015	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
AC611_13020	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
AC611_13065	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
AC611_13070	ENOG4105E08	Glycoside hydrolase, family 9
AC611_13080	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
AC611_13085	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
AC611_13100	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
AC611_13105	ENOG4106H78	methyltransferase
AC611_13110	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
AC611_13220	ENOG4105CMA	conjugation trbi family protein
AC611_13255	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
AC611_13325	ENOG4105CMM	transposase
AC611_13425	ENOG4105NVB	glycoside hydrolase, family 19
AC611_13470	ENOG4105ED4	portal protein
AC611_13500	ENOG4105CMM	transposase
AC611_13515	ENOG4108ZUW	Major pilin subunit
AC611_13535	ENOG4105D5G	Transposase
AC611_13540	ENOG4108HRK	Histidine kinase
AC611_13545	ENOG4105EWT	decarboxylase family
AC611_13550	ENOG4108KPZ	tonB-dependent Receptor
AC611_13555	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
AC611_13565	ENOG4105M2J	Glutaredoxin
AC611_13570	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
AC611_13575	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
AC611_13580	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
AC611_13590	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
AC611_13600	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
AC611_13605	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
AC611_13610	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
AC611_13615	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
AC611_13625	ENOG4105CHV	Transcription elongation factor NusA
AC611_13630	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
AC611_13640	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AC611_13645	ENOG4105C8S	subunit m
AC611_13650	ENOG4105D65	subunit l
AC611_13660	ENOG4105DF2	NADH dehydrogenase subunit j
AC611_13665	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AC611_13670	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
AC611_13675	ENOG4107R0R	NADH dehydrogenase subunit g
AC611_13680	ENOG4107QIZ	NADH dehydrogenase
AC611_13685	ENOG4105GKE	subunit e
AC611_13690	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AC611_13695	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AC611_13700	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AC611_13705	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AC611_13720	ENOG4105CP7	Triose-phosphate isomerase
AC611_13725	ENOG4105EMU	Dehydrogenase
AC611_13740	ENOG4105BZU	Histidine kinase
AC611_13760	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
AC611_13765	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
AC611_13770	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
AC611_13780	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
AC611_13790	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
AC611_13795	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
AC611_13815	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
AC611_13820	ENOG4105C5I	Dehydrogenase
AC611_13825	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
AC611_13830	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
AC611_13840	ENOG4105DJ4	phosphatidylserine decarboxylase
AC611_13850	ENOG4105D7A	ATP-binding protein
AC611_13870	ENOG4108RRZ	Transcription elongation factor GreB
AC611_13875	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
AC611_13900	ENOG4105DHP	deoxycytidine triphosphate deaminase
AC611_13940	ENOG4105C9K	Endothelin-converting enzyme 1
AC611_13965	ENOG4105DC8	reductase
AC611_13970	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
AC611_13980	ENOG4108YZY	peptidylprolyl cis-trans isomerase
AC611_13985	ENOG4105K4H	Nlp p60 protein
AC611_13990	ENOG4105K4H	Nlp p60 protein
AC611_14000	ENOG41082K6	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
AC611_14010	ENOG4105G6Z	alkaline phosphatase
AC611_14015	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
AC611_14020	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
AC611_14025	ENOG4105CTB	Polyprenyl synthetase
AC611_14040	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
AC611_14045	ENOG4105N42	UPF0307 protein
AC611_14050	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
AC611_14060	ENOG4105QD6	exported protein
AC611_14065	ENOG4105C03	ribonuclease
AC611_14070	ENOG4108Z03	MAF-like protein
AC611_14075	ENOG4105MPN	Membrane
AC611_14090	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
AC611_14105	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
AC611_14120	ENOG4105C8T	Leucyl-tRNA synthetase
AC611_14130	ENOG4107QR8	Thioredoxin
AC611_14155	ENOG4105WG9	Conserved Protein
AC611_14160	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
AC611_14210	ENOG4105BZ1	(ABC) transporter
AC611_14235	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
AC611_14240	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AC611_14245	ENOG4105BZU	Histidine kinase
AC611_14255	ENOG4105FQP	Beta-lactamase
AC611_14260	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
AC611_14275	ENOG4105BZU	Histidine kinase
AC611_14280	ENOG4105FE9	pseudouridine synthase
AC611_14285	ENOG4105BZU	Histidine kinase
AC611_14295	ENOG4105EMN	RNA polymerase sigma factor
AC611_14365	ENOG4105UGU	tonB-dependent Receptor
AC611_14410	ENOG4105CPC	Aldo Keto reductase
AC611_14415	ENOG4105F27	Major Facilitator
AC611_14420	ENOG4105CC0	LysR family Transcriptional regulator
AC611_14430	ENOG4105CF7	AraC family transcriptional regulator
AC611_14440	ENOG4108JGH	Tetr family transcriptional regulator
AC611_14445	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
AC611_14450	ENOG4105BZS	acriflavin resistance protein
AC611_14455	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
AC611_14465	ENOG4105MYN	Zinc uptake regulation protein
AC611_14470	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
AC611_14495	ENOG4105CT7	inner membrane cred family protein
AC611_14515	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
AC611_14520	ENOG4105D6S	protein involved in catabolism of external DNA
AC611_14540	ENOG4108JA2	transcriptioN-repair coupling factor
AC611_14550	ENOG4105CBS	Chea signal transduction histidine kinase
AC611_14555	ENOG4105C8Q	Methyl-accepting chemotaxis
AC611_14560	ENOG4108V3W	Chemotaxis protein, CheW
AC611_14565	ENOG4105BZU	Histidine kinase
AC611_14570	ENOG4105BZU	Histidine kinase
AC611_14575	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
AC611_14585	ENOG4105C9K	Endothelin-converting enzyme 1
AC611_14600	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
AC611_14615	ENOG4105EUB	pirin domain protein
AC611_14630	ENOG4105EUB	pirin domain protein
AC611_14635	ENOG4105D22	carbon starvation protein
AC611_14640	ENOG4105VCD	cytoplasmic protein
AC611_14685	ENOG4107XAN	XdhC and CoxI family
AC611_14690	ENOG4105C7W	Xanthine dehydrogenase
AC611_14695	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
AC611_14700	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
AC611_14715	ENOG4108UUM	single-stranded DNA-binding protein
AC611_14720	ENOG4105EAH	synthase
AC611_14730	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
AC611_14745	ENOG4105CFH	Aspartokinase
AC611_14750	ENOG4105JAB	phenazine biosynthesis protein, phzf family
AC611_14755	ENOG4105JAB	phenazine biosynthesis protein, phzf family
AC611_14765	ENOG4108Z9K	Osmotically inducible protein
AC611_14770	ENOG4105CXT	aspartate transcarbamylase
AC611_14775	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
AC611_14780	ENOG4108UJU	UPF0301 protein
AC611_14785	ENOG4108MAJ	Membrane
AC611_14790	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
AC611_14805	ENOG4105CZX	twitching motility protein
AC611_14810	ENOG4105CZX	twitching motility protein
AC611_14815	ENOG4105DFA	alanine racemase domain protein
AC611_14820	ENOG4105II7	pyrroline-5-carboxylate reductase
AC611_14830	ENOG4105FAA	peptidase M23
AC611_14850	ENOG4108Z0Z	intracellular protease Pfpi family
AC611_14870	ENOG4105C3K	feS assembly ATPase SufC
AC611_14875	ENOG4105JRK	feS assembly protein SufD
AC611_14880	ENOG4105C9B	Cysteine desulfurase
AC611_14885	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
AC611_14895	ENOG4108IU3	tonb-dependent siderophore receptor
AC611_14900	ENOG4107E2E	PKHD-type hydroxylase
AC611_14925	ENOG4105D5G	Transposase
AC611_14930	ENOG4105CJ2	(LipO)protein
AC611_14935	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
AC611_14940	ENOG41090B9	response to stress
AC611_14945	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
AC611_14960	ENOG4105EHM	Aminoglycoside phosphotransferase
AC611_14965	ENOG4108S0S	Nucleotidyl transferase
AC611_14975	ENOG4105C02	permease
AC611_14985	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
AC611_15000	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
AC611_15020	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
AC611_15030	ENOG4105C2X	Arabinose 5-phosphate isomerase
AC611_15035	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
AC611_15045	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
AC611_15050	ENOG4108IUZ	ABC transporter
AC611_15055	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AC611_15060	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
AC611_15065	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
AC611_15070	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
AC611_15075	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
AC611_15085	ENOG41080Z8	PHOSPHOCARRIER protein
AC611_15100	ENOG4105CJW	magnesium transporter
AC611_15105	ENOG4107UWA	esterase
AC611_15110	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
AC611_15175	ENOG4105CVE	Lytic murein transglycosylase
AC611_15240	ENOG4105C4M	(Ubiquinol oxidase) subunit I
AC611_15250	ENOG4105C85	amino acid
AC611_15255	ENOG4108NFF	pectate lyase
AC611_15265	ENOG4105CMM	transposase
AC611_15290	ENOG4105CUB	amino acid
AC611_15345	ENOG4108Z4X	TRANSCRIPTIONal
AC611_15355	ENOG4106032	Glutathionylspermidine synthase
AC611_15380	ENOG4108P9J	Phage shock protein A
AC611_15390	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
AC611_15395	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
AC611_15400	ENOG4105D49	3-dehydroquinate synthase
AC611_15410	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
AC611_15415	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
AC611_15420	ENOG4105BZU	Histidine kinase
AC611_15425	ENOG4105BZU	Histidine kinase
AC611_15430	ENOG4105BZU	Histidine kinase
AC611_15440	ENOG4105BZU	Histidine kinase
AC611_15445	ENOG4108YYC	ycei family
AC611_15465	ENOG4105EJQ	L-serine dehydratase
AC611_15475	ENOG4105CFH	Aspartokinase
AC611_15480	ENOG4105C28	cystathionine
AC611_15485	ENOG4106TYC	homoserine o-acetyltransferase (EC 2.3.1.31)
AC611_15490	ENOG4105DR5	peptidase
AC611_15495	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
AC611_15500	ENOG4108UT2	hemolysin iii
AC611_15505	ENOG41066T0	asmA family
AC611_15510	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
AC611_15520	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
AC611_15525	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
AC611_15535	ENOG4105D05	Receptor
AC611_15540	ENOG4108IG5	Transcriptional regulator
AC611_15550	ENOG4107QPN	acyl-Coa dehydrogenase
AC611_15575	ENOG4105D5G	Transposase
AC611_15595	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
AC611_15600	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
AC611_15610	ENOG4107QX8	SPFH domain, Band 7 family protein
AC611_15615	ENOG4105KK4	UPF0060 membrane protein
AC611_15625	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
AC611_15630	ENOG4107RK2	ADP-ribose diphosphatase NudE
AC611_15640	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
AC611_15645	ENOG4105CHC	glucokinase (EC 2.7.1.2)
AC611_15675	ENOG4105VRS	hydrolase family 18
AC611_15680	ENOG4105E2D	ec 3.2.1.52
AC611_15700	ENOG4105CWX	Alpha-1,2-mannosidase
AC611_15735	ENOG4106N3A	copper homeostasis protein cutc
AC611_15750	ENOG4105D9U	N-acetyltransferase
AC611_15765	ENOG4105CBS	Chea signal transduction histidine kinase
AC611_15770	ENOG4105C8Q	Methyl-accepting chemotaxis
AC611_15780	ENOG4105M3Z	response regulator
AC611_15785	ENOG4108UNF	response regulator
AC611_15790	ENOG4105D7Z	glutathione synthase
AC611_15800	ENOG41065RQ	ADP-ribosylation crystallin J1
AC611_15805	ENOG41072GX	Peptidase M22 Glycoprotease
AC611_15815	ENOG4105DVT	helicase
AC611_15825	ENOG4105BZ4	penicillin-binding protein
AC611_15840	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
AC611_15845	ENOG4105JIE	May be involved in the transport of PQQ or its precursor to the periplasm (By similarity)
AC611_15850	ENOG41086XE	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ (By similarity)
AC611_15855	ENOG4105Z85	coenzyme PQQ synthesis
AC611_15860	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
AC611_15875	ENOG4105CHC	glucokinase (EC 2.7.1.2)
AC611_15885	ENOG4105D5G	Transposase
AC611_15895	ENOG4105CQ7	ATP-dependent helicase
AC611_15905	ENOG4105C9U	ATP-dependent DNA helicase RecQ
AC611_15960	ENOG4105C8Q	Methyl-accepting chemotaxis
AC611_15980	ENOG410903D	sensor protein
AC611_15995	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
AC611_16005	ENOG4105KCK	Peptidoglycan-associated lipoprotein
AC611_16010	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
AC611_16025	ENOG4105E02	MotA TolQ exbB proton channel
AC611_16030	ENOG4107YD3	Thioesterase
AC611_16035	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
AC611_16045	ENOG4105DFH	Transport of potassium into the cell (By similarity)
AC611_16050	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
AC611_16055	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
AC611_16060	ENOG4105CDY	transcriptional regulatory protein
AC611_16075	ENOG4105C9M	aspartyl-trna synthetase
AC611_16090	ENOG4108ISG	Major Facilitator
AC611_16100	ENOG4105HSS	phospholipase C
AC611_16120	ENOG4105ETT	transcriptional Regulator, LysR family
AC611_16130	ENOG4105C5H	ABC transporter
AC611_16135	ENOG4107RNH	Outer membrane receptor FepA
AC611_16145	ENOG4107RNH	Outer membrane receptor FepA
AC611_16150	ENOG4107RNH	Outer membrane receptor FepA
AC611_16160	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
AC611_16185	ENOG4105GAV	receptor
AC611_16210	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
AC611_16235	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
AC611_16240	ENOG4108YZT	Adenosylcobinamide kinase
AC611_16245	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
AC611_16250	ENOG4105EFT	decarboxylase
AC611_16255	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
AC611_16260	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
AC611_16275	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
AC611_16285	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
AC611_16330	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
AC611_16335	ENOG4108K4C	ec 3.1.3.12
AC611_16340	ENOG4105BZP	glycoside hydrolase 15-related
AC611_16345	ENOG4105C1K	alpha-alpha-trehalose-phosphate synthase
AC611_16350	ENOG4105DZG	Dehydrogenase
AC611_16370	ENOG4105C8Q	Methyl-accepting chemotaxis
AC611_16375	ENOG4105KIR	Thiol-disulfide oxidoreductase dcc
AC611_16390	ENOG4105C34	Pseudouridine synthase
AC611_16395	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AC611_16405	ENOG4105C4K	Nad synthetase
AC611_16420	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
AC611_16425	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
AC611_16430	ENOG4107TUY	Histidine kinase
AC611_16440	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AC611_16445	ENOG4107QHF	type ii secretion system protein e
AC611_16450	ENOG4107QHF	type ii secretion system protein e
AC611_16465	ENOG4105D5G	Transposase
AC611_16475	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
AC611_16480	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
AC611_16495	ENOG4105BZU	Histidine kinase
AC611_16500	ENOG4105ETX	regulatoR
AC611_16510	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
AC611_16555	ENOG4105W5Q	DNA repair protein (RadC
AC611_16575	ENOG4105F2I	Transposase
AC611_16580	ENOG4105D5G	Transposase
AC611_16590	ENOG4105D5G	Transposase
AC611_16595	ENOG4105ESI	atpase involved in dna repair
AC611_16610	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
AC611_16615	ENOG4105KT5	UmuD protein
AC611_16635	ENOG4107QJE	Chromosome Partitioning Protein
AC611_16700	ENOG4108IYH	Dna topoisomerase
AC611_16705	ENOG4105NI8	Cytosine-specific methyltransferase
AC611_16795	ENOG4105D5G	Transposase
AC611_16990	ENOG4106NZI	LysR family Transcriptional regulator
AC611_17010	ENOG4105DFP	Integrase
AC611_17030	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
AC611_17035	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
AC611_17065	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
AC611_17080	ENOG4105ETE	Transcriptional regulator (LacI family
AC611_17105	ENOG4105C2N	RNA methyltransferase TrmH family group 3
AC611_17115	ENOG4105CD8	aminopeptidase N
AC611_17120	ENOG4105BZS	acriflavin resistance protein
AC611_17130	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
AC611_17135	ENOG4105C11	sulfate adenylyltransferase), subunit 2
AC611_17140	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
AC611_17145	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
AC611_17150	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
AC611_17170	ENOG4105BZU	Histidine kinase
AC611_17180	ENOG4107R11	Transcriptional regulator
AC611_17200	ENOG4108UVJ	appr-1-p processing domain protein
AC611_17205	ENOG4107R1Y	fructose-bisphosphate aldolase
AC611_17210	ENOG4105CA9	Pyruvate kinase
AC611_17220	ENOG4105BZA	Phosphoglycerate kinase
AC611_17250	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
AC611_17260	ENOG4105EIF	outer membrane protein W
AC611_17275	ENOG4107S76	domain protein
AC611_17280	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
AC611_17285	ENOG4105E0C	molybdate abc transporter
AC611_17290	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
AC611_17310	ENOG4105DHQ	Histidine kinase
AC611_17315	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
AC611_17335	ENOG4108IQE	Amp-dependent synthetase and ligase
AC611_17360	ENOG4107Y2H	ErfK ybiS ycfS ynhG family protein
AC611_17365	ENOG4105DR5	peptidase
AC611_17385	ENOG4105CV1	Transketolase (EC 2.2.1.1)
AC611_17390	ENOG4105CK2	sodium dicarboxylate symporter
AC611_17400	ENOG4107QVM	von Willebrand factor, type A
AC611_17420	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
AC611_17425	ENOG4105E4G	Type IV pilus
AC611_17450	ENOG4108JQC	penicillin-binding protein 1A
AC611_17465	ENOG4105NRA	50s ribosomal protein l31 type b
AC611_17470	ENOG4105DU0	nucleoside hydrolase
AC611_17475	ENOG4105CB5	ATP-dependent DNA helicase recG
AC611_17480	ENOG4105KME	endoribonuclease L-psp
AC611_17485	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
AC611_17490	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
AC611_17495	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
AC611_17500	ENOG4105DSJ	YicC domain protein
AC611_17505	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
AC611_17515	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
AC611_17520	ENOG4105CSA	Coproporphyrinogen iii oxidase
AC611_17535	ENOG4105D9Y	Splits dipeptides with a prolyl residue in the C- terminal position (By similarity)
AC611_17545	ENOG4107RAQ	aminopeptidase
AC611_17550	ENOG4105E07	UPF0149 protein
AC611_17560	ENOG4105W8B	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
AC611_17565	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
AC611_17585	ENOG41063JG	Transcriptional regulator
AC611_17590	ENOG4105VCQ	rubredoxin
AC611_17595	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
AC611_17625	ENOG41061ZR	Transcriptional regulator
AC611_17630	ENOG41090JD	Blue (Type 1) copper domain protein
AC611_17635	ENOG4105CIH	Imidazole acetol-phosphate transaminase
AC611_17665	ENOG4105C8Y	Acetylornithine aminotransferase
AC611_17670	ENOG4105EYW	Ion transport protein
AC611_17685	ENOG410841Q	phosphoesterase PA-phosphatase related protein
AC611_17690	ENOG4105FFC	UPF0187 protein
AC611_17700	ENOG4105DFU	Cell wall formation (By similarity)
AC611_17705	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
AC611_17720	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
AC611_17730	ENOG4105F0N	pyrophosphate phospho-hydrolase
AC611_17745	ENOG4105ECQ	AraC Family Transcriptional Regulator
AC611_17750	ENOG4108M3R	transcriptional activator CadC
AC611_17755	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
AC611_17765	ENOG4105C8Q	Methyl-accepting chemotaxis
AC611_17770	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
AC611_17775	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
AC611_17790	ENOG4105C7B	Threonine dehydratase
AC611_17795	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
AC611_17800	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
AC611_17805	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
AC611_17810	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
AC611_17815	ENOG4108MP6	LysR family Transcriptional regulator
AC611_17830	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
AC611_17835	ENOG4105DFG	type I secretion outer membrane protein
AC611_17840	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
AC611_17845	ENOG4105D1S	lipid A biosynthesis
AC611_17870	ENOG4105C6K	Malic enzyme
AC611_17875	ENOG4105CK2	sodium dicarboxylate symporter
AC611_17885	ENOG4105CQZ	Histidine kinase
AC611_17890	ENOG4105CSH	Transporter
AC611_17900	ENOG4105F04	LysR family Transcriptional regulator
AC611_17910	ENOG4105CPC	Aldo Keto reductase
AC611_17925	ENOG4105WH1	Two component transcriptional regulator luxr family
AC611_17930	ENOG4106JDA	Phosphoglycerate transport regulatory protein PGTC
AC611_17935	ENOG4105DHQ	Histidine kinase
AC611_17950	ENOG4105D4T	Citrate transporter
AC611_17955	ENOG4105CHR	reductase
AC611_17960	ENOG4105ETE	Transcriptional regulator (LacI family
AC611_17975	ENOG4107QW3	Sucrose phosphorylase
AC611_17990	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
AC611_17995	ENOG4105CHM	Aminotransferase
AC611_18030	ENOG41069H0	dihydroorotase EC 3.5.2.3
AC611_18035	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
AC611_18060	ENOG4105D5G	Transposase
AC611_18070	ENOG4108RMV	DegV Family
AC611_18090	ENOG4105C4W	S-formylglutathione hydrolase
AC611_18095	ENOG4108QBQ	Catalyzes the condensation of formaldehyde and glutathione to S-hydroxymethylglutathione (By similarity)
AC611_18120	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
AC611_18125	ENOG4105JJR	Histidine kinase
AC611_18150	ENOG4106RE7	Cytochrome
AC611_18160	ENOG4108Z33	Thiol disulfide Interchange Protein
AC611_18170	ENOG4105C94	Transporter
AC611_18175	ENOG4105C26	Dehydrogenase
AC611_18180	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
AC611_18205	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
AC611_18215	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
AC611_18220	ENOG4105VFQ	Histone family protein nucleoid-structuring protein H-NS
AC611_18235	ENOG4105DHJ	ABC, transporter
AC611_18240	ENOG4108SNX	Mammalian cell entry related domain protein
AC611_18255	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
AC611_18270	ENOG4107QKV	phosphomannomutase
AC611_18275	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
AC611_18285	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
AC611_18290	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
AC611_18305	ENOG4105BZJ	Electron transfer flavoprotein
AC611_18310	ENOG4105C10	Electron transfer flavoprotein
AC611_18325	ENOG4105IQ5	FAD linked oxidase domain protein
AC611_18335	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
AC611_18370	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
AC611_18375	ENOG4105CGN	Glycosyl transferase (Group 1
AC611_18385	ENOG4105EY8	ABC transporter
AC611_18415	ENOG4105C28	cystathionine
AC611_18440	ENOG4105CZX	twitching motility protein
AC611_18445	ENOG4108RXX	maleylacetoacetate isomerase
AC611_18455	ENOG4105C1J	atp-dependent rna helicase
AC611_18460	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
AC611_18470	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
AC611_18490	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
AC611_18495	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
AC611_18500	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
AC611_18510	ENOG4106MWK	domain protein
AC611_18520	ENOG4105DGW	oligopeptidase A
AC611_18535	ENOG4105E3B	Multicopper oxidase
AC611_18570	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
AC611_18575	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
AC611_18580	ENOG4105C19	ABC transporter
AC611_18585	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AC611_18600	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AC611_18610	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
AC611_18625	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
AC611_18630	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
AC611_18635	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
AC611_18640	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
AC611_18645	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
AC611_18650	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
AC611_18655	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
AC611_18660	ENOG4107RAZ	it plays a direct role in the translocation of protons across the membrane (By similarity)
AC611_18680	ENOG4107QN2	dihydrolipoyl dehydrogenase
AC611_18690	ENOG4107QSN	dihydrolipoamide acetyltransferase
AC611_18725	ENOG4105D01	(LipO)protein
AC611_18730	ENOG4108UMI	ABC transporter, permease
AC611_18735	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
AC611_18740	ENOG4108EHX	EamA-like transporter family
AC611_18745	ENOG4108VPT	UPF0234 protein
AC611_18755	ENOG4105BZU	Histidine kinase
AC611_18775	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
AC611_18780	ENOG4107S75	HAD-superfamily hydrolase subfamily IA variant 3
AC611_18785	ENOG4105I08	Pseudouridine synthase
AC611_18790	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
AC611_18800	ENOG4105F2I	Transposase
AC611_18805	ENOG4105D5G	Transposase
AC611_18820	ENOG4105BZU	Histidine kinase
AC611_18840	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
AC611_18845	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
AC611_18850	ENOG4105EW9	transcriptional regulator AsnC family
AC611_18870	ENOG4107RD7	Flagellar Motor Protein, MotA
AC611_18875	ENOG4105ER2	Ompa motb domain protein
AC611_18900	ENOG4105E3A	(ABC) transporter
AC611_18905	ENOG4105DA5	(ABC) transporter
AC611_18910	ENOG4105EEQ	Na H antiporter
AC611_18920	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
AC611_18930	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
AC611_18940	ENOG4105CBN	LysR family transcriptional regulator
AC611_18950	ENOG4105CPC	Aldo Keto reductase
AC611_18960	ENOG4105C9K	Endothelin-converting enzyme 1
AC611_18975	ENOG4107QTZ	amino acid
AC611_18985	ENOG4108VAC	response regulator
AC611_18990	ENOG4105C2F	Histidine kinase
AC611_19005	ENOG4108Z9Z	response to DNA damage stimulus
AC611_19010	ENOG4105WEF	catalase
AC611_19030	ENOG4105BZU	Histidine kinase
AC611_19045	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AC611_19060	ENOG4105C4M	(Ubiquinol oxidase) subunit I
AC611_19065	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
AC611_19080	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
AC611_19100	ENOG4105E2A	Dehydrogenase
AC611_19110	ENOG4105D5G	Transposase
AC611_19160	ENOG4105CIG	ABC transporter
AC611_19175	ENOG4108UQ8	endoribonuclease L-psp
AC611_19205	ENOG4105CHH	sulfate transporter
AC611_19210	ENOG4105CMQ	Chloride channel
AC611_19255	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AC611_19260	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
AC611_19265	ENOG4105D1S	lipid A biosynthesis
AC611_19270	ENOG4108Z7F	N-acetyltransferase
AC611_19315	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
AC611_19320	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
AC611_19325	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
AC611_19330	ENOG4108WZM	domain protein
AC611_19335	ENOG4105C79	DNA protecting protein DprA
AC611_19340	ENOG4108RPN	Protein smg homolog
AC611_19355	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
AC611_19360	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
AC611_19375	ENOG4105CHR	reductase
AC611_19385	ENOG4105D07	Signal peptide peptidase, SppA
AC611_19390	ENOG4107QI1	Mate efflux family protein
AC611_19410	ENOG4105C25	Primosomal protein n'
AC611_19415	ENOG4108TGY	Glutathione S-transferase
AC611_19435	ENOG4105EN6	Membrane
AC611_19440	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AC611_19445	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
AC611_19450	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
AC611_19455	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
AC611_19460	ENOG4105CAK	Cell division ATP-binding protein ftsE
AC611_19465	ENOG4105C1J	atp-dependent rna helicase
AC611_19470	ENOG4105K63	Thioredoxin
AC611_19475	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
AC611_19485	ENOG4105VS7	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity)
AC611_19500	ENOG4105E9K	Isocitrate dehydrogenase
AC611_19510	ENOG4109066	lysm domain bon superfamily protein
AC611_19515	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
AC611_19520	ENOG4105CH2	amidohydrolase
AC611_19525	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
AC611_19530	ENOG4105BZS	acriflavin resistance protein
AC611_19550	ENOG4105E32	cytoplasmic protein
AC611_19575	ENOG4105D5G	Transposase
AC611_19595	ENOG4108UQS	dipeptidase
AC611_19600	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
AC611_19620	ENOG4105D5Q	Arginine ornithine antiporter
AC611_19640	ENOG4105D5G	Transposase
AC611_19665	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
AC611_19670	ENOG4107ZVW	dihydroneopterin aldolase
AC611_19675	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
AC611_19680	ENOG4105VCC	30S ribosomal protein S21
AC611_19685	ENOG4105KTH	gatB Yqey
AC611_19695	ENOG4107S2Z	UPF0761 membrane protein
AC611_19700	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
AC611_19705	ENOG4105DHU	Bile acid
AC611_19715	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
AC611_19740	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
AC611_19745	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
AC611_19760	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
AC611_19800	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
AC611_19805	ENOG4105DR5	peptidase
AC611_19810	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
AC611_19820	ENOG4105EYM	Major Facilitator superfamily
AC611_19825	ENOG4105CGK	Exodeoxyribonuclease III
AC611_19830	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
AC611_19840	ENOG4107QJE	Chromosome Partitioning Protein
AC611_19845	ENOG4105FA0	parb-like partition protein
AC611_19860	ENOG4105CKK	Glycosyl transferase, family 2
AC611_19880	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
AC611_19885	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
AC611_19890	ENOG4105W5Q	DNA repair protein (RadC
AC611_19895	ENOG4105C75	arginyL-tRNA synthetase
AC611_19910	ENOG4105EMU	Dehydrogenase
AC611_19920	ENOG4105EXC	Acyl-transferase
AC611_19930	ENOG4105CEY	Amp-dependent synthetase and ligase
AC611_19935	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
AC611_19940	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
AC611_19965	ENOG4105CPE	K01197 hyaluronoglucosaminidase EC 3.2.1.35
AC611_19970	ENOG4108YZA	Nitrogen regulatory protein pii
AC611_19975	ENOG4105W0Z	cytoplasmic protein
AC611_19980	ENOG4105C0P	Mg chelatase subunit ChlI
AC611_19995	ENOG41066DG	(EAL) domain protein
AC611_20010	ENOG4105EJ2	Transcriptional regulator
AC611_20030	ENOG4105E0Y	RtcB Protein
AC611_20070	ENOG4105ECP	epimerase
AC611_20075	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
AC611_20080	ENOG4105DHQ	Histidine kinase
AC611_20100	ENOG4105C0H	protease
AC611_20120	ENOG4105DSF	transport protein
AC611_20125	ENOG4105DFC	had-superfamily hydrolase, subfamily ia, variant
AC611_20130	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
AC611_20145	ENOG4107VGR	Catalase
AC611_20165	ENOG4108S01	response regulator
AC611_20170	ENOG4108ZGX	Histidine kinase
AC611_20175	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
AC611_20180	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AC611_20205	ENOG4105FDR	Membrane
AC611_20225	ENOG4108NNI	Beta-lactamase domain-containing protein
AC611_20230	ENOG4105C31	Tryptophanyl-tRNA synthetase
AC611_20235	ENOG4105VDW	Csbd family
AC611_20295	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
AC611_20305	ENOG4105EXZ	Involved in the regulation of ptsG expression by binding and inactivating Mlc (By similarity)
AC611_20320	ENOG4105EB3	Histidine kinase
AC611_20325	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
AC611_20335	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
AC611_20350	ENOG4105CH6	catalase
AC611_20375	ENOG4105D5G	Transposase
AC611_20385	ENOG4108MBX	Secretion Protein
AC611_20390	ENOG4105DVT	helicase
AC611_20405	ENOG4105E2X	shikimate dehydrogenase
AC611_20425	ENOG4105D52	delta-aminolevulinic acid dehydratase
AC611_20480	ENOG4105QV4	Tryptophan halogenase
AC611_20495	ENOG4108IUW	ABC transporter
AC611_20505	ENOG4105VZ8	Transcriptional regulator
AC611_20525	ENOG4105PGM	cation diffusion facilitator family transporter
AC611_20530	ENOG4108JA0	Oxidoreductase, FAD NAD(P)-binding domain protein
AC611_20535	ENOG4105DA5	(ABC) transporter
AC611_20540	ENOG4105E3A	(ABC) transporter
AC611_20545	ENOG41063V1	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
AC611_20575	ENOG4105K63	Thioredoxin
AC611_20595	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
AC611_20600	ENOG4107QYD	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
AC611_20610	ENOG4105CD5	CoA-binding domain protein
AC611_20615	ENOG4105CJW	magnesium transporter
AC611_20640	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
AC611_20645	ENOG4105BZP	glycoside hydrolase 15-related
AC611_20665	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
AC611_20675	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
AC611_20685	ENOG4105C2D	reductase
AC611_20725	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
AC611_20730	ENOG4105E9Q	Acyl-transferase
AC611_20740	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
AC611_20780	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
AC611_20785	ENOG4105C2M	dna polymerase I
AC611_20815	ENOG4107TPY	serine threonine protein kinase
AC611_20820	ENOG4108ZF3	Phosphatase
AC611_20845	ENOG4107S5I	aldo keto reductase
AC611_20850	ENOG410642W	LysR family Transcriptional regulator
AC611_20865	ENOG4105CS6	Rhs element vgr protein
AC611_20920	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
AC611_20950	ENOG4105D5G	Transposase
AC611_20955	ENOG4105F2I	Transposase
AC611_21000	ENOG4108WC9	type VI secretion system effector, hcp1 family
AC611_21035	ENOG4105C4R	Atp-dependent dna helicase
AC611_21050	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
AC611_21055	ENOG4108KB2	LysR family Transcriptional regulator
AC611_21060	ENOG4105JSC	dimethylmenaquinone methyltransferase
AC611_21070	ENOG4105KHM	amidohydrolase 2
AC611_21075	ENOG4105W0E	50S ribosomal protein L33
AC611_21080	ENOG4105KDC	50s ribosomal protein l28
AC611_21105	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
AC611_21125	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
AC611_21130	ENOG4105DGI	Alkaline phosphatase
AC611_21160	ENOG4105CGK	Exodeoxyribonuclease III
AC611_21165	ENOG4105E2R	ROK family
AC611_21185	ENOG4107QN1	sodium solute
AC611_21190	ENOG41062QD	Membrane
AC611_21200	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
AC611_21225	ENOG4105DSG	hydrolase family 43
AC611_21245	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
AC611_21250	ENOG4105ERH	Fumarylacetoacetate hydrolase
AC611_21255	ENOG4105DIA	mandelate racemase muconate lactonizing
AC611_21260	ENOG4105QJH	Domain of unknown function (DUF718)
AC611_21265	ENOG4105EDR	glucose galactose transporter
AC611_21270	ENOG4108K2P	TRANSCRIPTIONal
AC611_21275	ENOG4106HBX	Transcriptional Regulator AraC Family
AC611_21285	ENOG4108UI1	Probably functions as a manganese efflux pump (By similarity)
AC611_21290	ENOG4105BZU	Histidine kinase
AC611_21300	ENOG4105E2V	Glycosyltransferase 36
AC611_21305	ENOG4105CT4	transporter
AC611_21310	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
AC611_21335	ENOG4105MA0	exported protein
AC611_21340	ENOG4105CFU	surface antigen
AC611_21345	ENOG4105D05	Receptor
AC611_21355	ENOG4107RDJ	Sulfotransferase
AC611_21365	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
AC611_21370	ENOG4107QHF	type ii secretion system protein e
AC611_21380	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
AC611_21395	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
AC611_21400	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
AC611_21415	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
AC611_21445	ENOG4105DH7	May be involved in recombination (By similarity)
AC611_21450	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
AC611_21455	ENOG4105C93	Xylose Isomerase
AC611_21460	ENOG4105ETE	Transcriptional regulator (LacI family
AC611_21465	ENOG4105D0H	Alpha-glucuronidase (EC 3.2.1.139)
AC611_21475	ENOG4105CXK	mandelate racemase muconate lactonizing
AC611_21490	ENOG4105DEI	Mannitol dehydrogenase
AC611_21545	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
AC611_21575	ENOG4105D9F	endo-1,4-beta-xylanase (EC 3.2.1.8)
AC611_21580	ENOG4105CNT	hydrolase family 2
AC611_21585	ENOG4105D2H	Uronic isomerase
AC611_21615	ENOG4105CT4	transporter
AC611_21620	ENOG4105DT9	hydrolase family 43
AC611_21685	ENOG4105E55	glycerol-3-phosphate acyltransferase
AC611_21695	ENOG4105ETE	Transcriptional regulator (LacI family
AC611_21715	ENOG4105QV4	Tryptophan halogenase
AC611_21720	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
AC611_21725	ENOG4105CUR	5'-nucleotidase, lipoprotein e(p4) family
AC611_21730	ENOG4108YXG	UPF0502 protein
AC611_21740	ENOG4105CSA	Coproporphyrinogen iii oxidase
AC611_21795	ENOG4105C4R	Atp-dependent dna helicase
AC611_21800	ENOG4107104	thymidine kinase
AC611_21805	ENOG4105BZU	Histidine kinase
AC611_21810	ENOG4105DJ9	glucan biosynthesis protein
AC611_21830	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
AC611_21860	ENOG4105DKK	Benzoate
AC611_21885	ENOG4105DSB	aldose 1-epimerase
AC611_21895	ENOG4105K5B	UPF0225 protein
AC611_21960	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
AC611_21970	ENOG4105EMU	Dehydrogenase
AC611_21975	ENOG410642W	LysR family Transcriptional regulator
AC611_21985	ENOG4105CSH	Transporter
AC611_21990	ENOG4105DR8	Membrane
AC611_22000	ENOG4105Y49	secretion protein, HlyD family
AC611_22005	ENOG4105ZQC	membrane protein AaeX
AC611_22015	ENOG4105EUJ	GTP cyclohydrolase i
AC611_22035	ENOG4105D5G	Transposase
AC611_22045	ENOG4105EJ9	Membrane
AC611_22060	ENOG4105D5G	Transposase
AC611_22085	ENOG4105D3G	Pseudouridine synthase
AC611_22170	ENOG4108TN6	type iii secretion
AC611_22180	ENOG41075IY	surface presentation of antigens protein SpaP
AC611_22200	ENOG4108JIR	Flagellum-specific ATP synthase
AC611_22210	ENOG4108HR8	type iii secretion
AC611_22215	ENOG4108N8R	Invasion protein
AC611_22235	ENOG4105Y7Q	type iii secretion
AC611_22315	ENOG4105F2I	Transposase
AC611_22400	ENOG4105CMM	transposase
AC611_22425	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
AC611_22455	ENOG4105CBZ	Short-chain dehydrogenase reductase Sdr
AC611_22485	ENOG4105VDM	plasmid maintenance system antidote protein, xre family
AC611_22495	ENOG4107QYX	exodeoxyribonuclease v alpha
AC611_22500	ENOG4107QKA	exodeoxyribonuclease V beta
AC611_22505	ENOG4105DSY	exodeoxyribonuclease V, gamma
AC611_22540	ENOG4105DHJ	ABC, transporter
AC611_22545	ENOG4105CY3	ABC transporter, permease
AC611_22550	ENOG4107PE3	Mammalian cell entry related domain protein
AC611_22565	ENOG410903C	(LipO)protein
AC611_22580	ENOG4108V06	Glutathione peroxidase
AC611_22590	ENOG4107QSV	RmuC domain protein
AC611_22600	ENOG4105EJC	lysr family transcriptional regulator
AC611_22625	ENOG4105CUB	amino acid
AC611_22630	ENOG4105CWX	Alpha-1,2-mannosidase
AC611_22635	ENOG4105NRM	Membrane
AC611_22640	ENOG4105BZU	Histidine kinase
AC611_22645	ENOG4108IXP	Carbohydrate diacid transcriptional activator CdaR
AC611_22650	ENOG4105BZW	Glycerate kinase
AC611_22670	ENOG4105DR4	Methyltransferase
AC611_22675	ENOG4105DU1	integral membrane protein, terc
AC611_22685	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
AC611_22705	ENOG4108ZJ4	polysaccharide deacetylase
AC611_22710	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
AC611_22715	ENOG41067YR	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
AC611_22760	ENOG4105XEZ	This methylase recognizes the double-stranded sequence TCGA, causes specific methylation on A-4 on both strands and protects the DNA from cleavage by the
AC611_22835	ENOG4105D5G	Transposase
AC611_22885	ENOG4108C33	Resolvase
AC611_22910	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
AC611_23085	ENOG4106H6R	UPF0380 protein
AC611_23120	ENOG4105D5G	Transposase
AC611_23125	ENOG4105F2I	Transposase
AC611_23195	ENOG4105D5G	Transposase
AC611_23260	ENOG4108C33	Resolvase
AC611_23350	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)