locus-tag	class	description
OM951_00005	COG2963	transposase activity
OM951_00010	COG3104	oligopeptide transport
OM951_00030	COG2852	Protein conserved in bacteria
OM951_00035	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
OM951_00055	COG1320	monovalent cation:proton antiporter activity
OM951_00060	COG2212	antiporter activity
OM951_00070	COG0651	ATP synthesis coupled electron transport
OM951_00075	COG1006	Multisubunit Na H antiporter MnhC subunit
OM951_00080	COG2111	Na H antiporter
OM951_00080	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
OM951_00100	COG3179	chitinase
OM951_00120	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
OM951_00125	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
OM951_00145	COG1597	lipid kinase activity
OM951_00175	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
OM951_00180	COG0134	indole-3-glycerol-phosphate synthase activity
OM951_00190	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OM951_00195	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
OM951_00205	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
OM951_00215	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
OM951_00230	COG1051	belongs to the nudix hydrolase family
OM951_00270	COG0316	Belongs to the HesB IscA family
OM951_00285	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
OM951_00300	COG2814	Major facilitator Superfamily
OM951_00310	COG2814	Major facilitator Superfamily
OM951_00315	COG1289	transmembrane transporter activity
OM951_00325	COG0151	Belongs to the GarS family
OM951_00335	COG0138	bifunctional purine biosynthesis protein purh
OM951_00340	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
OM951_00345	COG2267	carboxylic ester hydrolase activity
OM951_00350	COG2453	phosphatase
OM951_00350	COG0671	phosphoesterase, PA-phosphatase related
OM951_00375	COG4589	Belongs to the CDS family
OM951_00380	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
OM951_00400	COG2264	protein methyltransferase activity
OM951_00415	COG0439	Biotin carboxylase
OM951_00425	COG0511	ligase activity, forming carbon-carbon bonds
OM951_00430	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
OM951_00440	COG1324	tolerance protein
OM951_00460	COG0459	protein refolding
OM951_00475	COG3550	peptidyl-serine autophosphorylation
OM951_00480	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
OM951_00505	COG3386	PFAM SMP-30 Gluconolaconase
OM951_00515	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
OM951_00520	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
OM951_00540	COG3039	Transposase
OM951_00560	COG0778	Nitroreductase
OM951_00565	COG2353	YceI-like domain
OM951_00600	COG3052	prosthetic group binding
OM951_00625	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
OM951_00635	COG1802	Transcriptional regulator
OM951_00690	COG3328	transposase activity
OM951_00745	COG1959	2 iron, 2 sulfur cluster binding
OM951_00770	COG0697	spore germination
OM951_00775	COG4305	rare lipoprotein A
OM951_00780	COG5297	Belongs to the glycosyl hydrolase family 6
OM951_00790	COG1113	amino acid transport
OM951_00800	COG0598	Magnesium transport protein CorA
OM951_00845	COG5002	protein histidine kinase activity
OM951_00845	COG5001	Diguanylate cyclase
OM951_00845	COG3447	MASE1 domain protein
OM951_00855	COG2205	protein histidine kinase activity
OM951_00855	COG0784	Response regulator, receiver
OM951_00885	COG2943	transferase activity, transferring hexosyl groups
OM951_00895	COG3275	phosphorelay sensor kinase activity
OM951_00905	COG0181	hydroxymethylbilane synthase activity
OM951_00940	COG1505	serine-type exopeptidase activity
OM951_00950	COG0436	Aminotransferase
OM951_00960	COG2832	Protein of unknown function (DUF454)
OM951_00970	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
OM951_00980	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
OM951_00985	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
OM951_00990	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
OM951_01015	COG2226	methyltransferase
OM951_01020	COG5001	Diguanylate cyclase
OM951_01020	COG3300	MHYT domain
OM951_01025	COG0308	aminopeptidase N
OM951_01070	COG3284	Transcriptional regulator
OM951_01085	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OM951_01090	COG1077	Cell shape determining protein MreB Mrl
OM951_01095	COG1792	Involved in formation and maintenance of cell shape
OM951_01110	COG0772	Belongs to the SEDS family
OM951_01150	COG2951	lytic endotransglycosylase activity
OM951_01155	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
OM951_01160	COG1686	Belongs to the peptidase S11 family
OM951_01170	COG2921	Belongs to the UPF0250 family
OM951_01175	COG0321	lipoyl(octanoyl) transferase activity
OM951_01180	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
OM951_01205	COG1056	cytidyltransferase-related domain
OM951_01205	COG1051	belongs to the nudix hydrolase family
OM951_01240	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
OM951_01245	COG0673	inositol 2-dehydrogenase activity
OM951_01250	COG2823	Periplasmic or secreted lipoprotein
OM951_01255	COG4251	negative regulation of phosphorylation
OM951_01260	COG0784	Response regulator, receiver
OM951_01265	COG4191	Histidine kinase
OM951_01270	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
OM951_01325	COG1459	type II secretion system
OM951_01370	COG2188	Transcriptional regulator
OM951_01380	COG1609	Transcriptional regulator
OM951_01385	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
OM951_01390	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
OM951_01400	COG0617	tRNA 3'-terminal CCA addition
OM951_01405	COG3039	Transposase
OM951_01420	COG0525	valine-tRNA ligase activity
OM951_01435	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
OM951_01445	COG0795	lipopolysaccharide-transporting ATPase activity
OM951_01460	COG4974	Belongs to the 'phage' integrase family
OM951_01470	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
OM951_01475	COG0047	phosphoribosylformylglycinamidine synthase activity
OM951_01475	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
OM951_01480	COG5295	Hep Hag repeat protein
OM951_01485	COG1404	Belongs to the peptidase S8 family
OM951_01495	COG1404	Belongs to the peptidase S8 family
OM951_01500	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
OM951_01505	COG1459	type II secretion system
OM951_01510	COG2165	general secretion pathway protein
OM951_01515	COG4970	Tfp pilus assembly protein FimT
OM951_01520	COG2165	general secretion pathway protein
OM951_01525	COG4795	General secretion pathway protein
OM951_01530	COG3156	type II secretion system protein K
OM951_01535	COG3166	PFAM Fimbrial assembly family protein
OM951_01550	COG1450	Type ii and iii secretion system protein
OM951_01565	COG2188	Transcriptional regulator
OM951_01635	COG1215	transferase activity, transferring glycosyl groups
OM951_01640	COG1215	transferase activity, transferring glycosyl groups
OM951_01645	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
OM951_01670	COG0242	peptide deformylase activity
OM951_01675	COG0488	(ABC) transporter
OM951_01685	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
OM951_01690	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
OM951_01700	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OM951_01700	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OM951_01720	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
OM951_01725	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
OM951_01730	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
OM951_01745	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
OM951_01750	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
OM951_01760	COG2205	protein histidine kinase activity
OM951_01765	COG0745	RESPONSE REGULATOR receiver
OM951_01780	COG1988	membrane-bound metal-dependent
OM951_01785	COG0792	nuclease activity
OM951_01825	COG3116	cell division
OM951_01835	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
OM951_01840	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
OM951_01845	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
OM951_01855	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
OM951_01860	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
OM951_01865	COG1181	Belongs to the D-alanine--D-alanine ligase family
OM951_01870	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
OM951_01885	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
OM951_01895	COG0739	heme binding
OM951_01900	COG0653	protein targeting
OM951_01905	COG0494	nUDIX hydrolase
OM951_01915	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
OM951_01925	COG0604	alcohol dehydrogenase
OM951_01925	COG1028	Short-chain dehydrogenase reductase Sdr
OM951_01925	COG3321	synthase
OM951_01940	COG0366	Alpha amylase catalytic
OM951_01975	COG2226	methyltransferase
OM951_01980	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
OM951_01990	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
OM951_02030	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
OM951_02040	COG4106	trans-aconitate 2-methyltransferase activity
OM951_02045	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OM951_02060	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OM951_02065	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
OM951_02070	COG0667	Aldo Keto reductase
OM951_02080	COG4771	TonB-dependent receptor
OM951_02100	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OM951_02105	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
OM951_02115	COG2175	clavaminate synthase activity
OM951_02125	COG4181	ATPase activity
OM951_02140	COG0642	Histidine kinase
OM951_02150	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
OM951_02160	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
OM951_02170	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
OM951_02175	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
OM951_02190	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
OM951_02195	COG2967	ApaG domain
OM951_02200	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
OM951_02205	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
OM951_02210	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
OM951_02215	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
OM951_02225	COG0123	including yeast histone deacetylase and acetoin utilization protein
OM951_02230	COG2096	Adenosyltransferase
OM951_02240	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OM951_02245	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OM951_02275	COG3384	dioxygenase
OM951_02280	COG0583	DNA-binding transcription factor activity
OM951_02285	COG0318	PFAM AMP-dependent synthetase and ligase
OM951_02295	COG1024	Enoyl-CoA hydratase
OM951_02315	COG3386	PFAM SMP-30 Gluconolaconase
OM951_02325	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
OM951_02350	COG0697	spore germination
OM951_02360	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OM951_02380	COG2205	protein histidine kinase activity
OM951_02385	COG2197	response regulator
OM951_02395	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OM951_02410	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
OM951_02415	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
OM951_02420	COG0583	DNA-binding transcription factor activity
OM951_02425	COG3634	alkyl hydroperoxide reductase activity
OM951_02435	COG2890	protein-(glutamine-N5) methyltransferase activity
OM951_02455	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OM951_02455	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OM951_02510	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
OM951_02515	COG1404	Belongs to the peptidase S8 family
OM951_02520	COG1404	Belongs to the peptidase S8 family
OM951_02525	COG1404	Belongs to the peptidase S8 family
OM951_02530	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
OM951_02555	COG1295	ribonuclease BN
OM951_02560	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OM951_02565	COG1254	Belongs to the acylphosphatase family
OM951_02580	COG0521	Mo-molybdopterin cofactor biosynthetic process
OM951_02590	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
OM951_02595	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
OM951_02605	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
OM951_02610	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
OM951_02620	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
OM951_02625	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
OM951_02630	COG0193	aminoacyl-tRNA hydrolase activity
OM951_02635	COG0012	GTP binding
OM951_02655	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
OM951_02670	COG0250	Participates in transcription elongation, termination and antitermination
OM951_02675	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
OM951_02680	COG0081	regulation of translation
OM951_02685	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
OM951_02695	COG0085	RNA polymerase activity
OM951_02700	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
OM951_02705	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
OM951_02710	COG0049	tRNA binding
OM951_02715	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
OM951_02720	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
OM951_02740	COG3328	transposase activity
OM951_02745	COG0051	transcription antitermination factor activity, RNA binding
OM951_02750	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
OM951_02755	COG0088	Forms part of the polypeptide exit tunnel
OM951_02760	COG0089	rRNA binding
OM951_02765	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
OM951_02770	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
OM951_02780	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
OM951_02785	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
OM951_02790	COG0255	Belongs to the universal ribosomal protein uL29 family
OM951_02795	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
OM951_02805	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
OM951_02810	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
OM951_02820	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
OM951_02825	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
OM951_02830	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
OM951_02840	COG1841	ribosomal large subunit assembly
OM951_02845	COG0200	Binds to the 23S rRNA
OM951_02850	COG0201	protein transport
OM951_02875	COG0203	ribosomal protein L17
OM951_02880	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
OM951_02900	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
OM951_02910	COG0154	amidase activity
OM951_02920	COG1217	gtp-binding protein TYPA
OM951_02925	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
OM951_02930	COG0039	L-malate dehydrogenase activity
OM951_02935	COG0625	glutathione transferase activity
OM951_02950	COG0446	pyridine nucleotide-disulphide oxidoreductase
OM951_02950	COG1902	pentaerythritol trinitrate reductase activity
OM951_02955	COG0604	alcohol dehydrogenase
OM951_02965	COG3328	transposase activity
OM951_02975	COG2885	chlorophyll binding
OM951_02995	COG0156	8-amino-7-oxononanoate synthase activity
OM951_03000	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
OM951_03005	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
OM951_03010	COG4208	sulfate ABC transporter
OM951_03015	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
OM951_03050	COG0406	alpha-ribazole phosphatase activity
OM951_03060	COG0285	dihydrofolate synthase activity
OM951_03080	COG2833	Protein of unknown function (DUF455)
OM951_03090	COG3291	Pkd domain containing protein
OM951_03100	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
OM951_03105	COG0671	phosphoesterase, PA-phosphatase related
OM951_03110	COG0438	transferase activity, transferring glycosyl groups
OM951_03120	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
OM951_03135	COG4783	chaperone-mediated protein folding
OM951_03150	COG0473	3-isopropylmalate dehydrogenase activity
OM951_03190	COG3328	transposase activity
OM951_03205	COG0544	peptidyl-prolyl cis-trans isomerase activity
OM951_03215	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
OM951_03245	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
OM951_03255	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OM951_03265	COG0328	RNA-DNA hybrid ribonuclease activity
OM951_03270	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
OM951_03275	COG0631	protein serine/threonine phosphatase activity
OM951_03300	COG0859	PFAM glycosyl transferase family 9
OM951_03305	COG3642	lipopolysaccharide core region biosynthetic process
OM951_03310	COG1234	tRNA 3'-trailer cleavage
OM951_03315	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
OM951_03325	COG0315	cyclic pyranopterin monophosphate synthase activity
OM951_03330	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
OM951_03335	COG0314	molybdopterin synthase activity
OM951_03355	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
OM951_03360	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
OM951_03365	COG0537	adenosine 5'-monophosphoramidase activity
OM951_03385	COG0714	Associated with various cellular activities
OM951_03395	COG0424	maF-like protein
OM951_03400	COG1399	metal-binding, possibly nucleic acid-binding protein
OM951_03405	COG0333	Belongs to the bacterial ribosomal protein bL32 family
OM951_03410	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OM951_03425	COG1028	Short-chain dehydrogenase reductase Sdr
OM951_03440	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
OM951_03445	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
OM951_03475	COG3829	transcription factor binding
OM951_03495	COG3328	transposase activity
OM951_03525	COG2373	Large extracellular alpha-helical protein
OM951_03545	COG3852	Histidine kinase
OM951_03550	COG4953	penicillin-binding protein 1C
OM951_03560	COG0678	peroxiredoxin activity
OM951_03580	COG0330	HflC and HflK could
OM951_03585	COG0330	HflC and HflK could
OM951_03595	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
OM951_03600	COG0308	aminopeptidase N
OM951_03610	COG1028	Short-chain dehydrogenase reductase Sdr
OM951_03615	COG1309	transcriptional regulator
OM951_03640	COG3328	transposase activity
OM951_03690	COG3387	PFAM Glycoside hydrolase 15-related
OM951_03695	COG1028	Short-chain dehydrogenase reductase Sdr
OM951_03700	COG3537	Alpha-1,2-mannosidase
OM951_03725	COG0492	ferredoxin-NADP+ reductase activity
OM951_03755	COG1529	Aldehyde oxidase and xanthine dehydrogenase
OM951_03760	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
OM951_03765	COG2080	2 iron, 2 sulfur cluster binding
OM951_03800	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
OM951_03815	COG0587	DNA-directed DNA polymerase activity
OM951_03835	COG1297	OPT oligopeptide transporter protein
OM951_03860	COG1506	peptidase
OM951_03860	COG0823	Involved in the tonB-independent uptake of proteins
OM951_03890	COG2207	Transcriptional regulator
OM951_03890	COG1917	Cupin 2, conserved barrel domain protein
OM951_03905	COG0753	catalase activity
OM951_03910	COG0656	L-ascorbic acid biosynthetic process
OM951_03920	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
OM951_03920	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
OM951_03970	COG2194	sulfuric ester hydrolase activity
OM951_03985	COG0745	RESPONSE REGULATOR receiver
OM951_03990	COG0642	Histidine kinase
OM951_04000	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
OM951_04005	COG2894	cell division
OM951_04010	COG0850	regulation of cytokinetic process
OM951_04020	COG4585	Histidine kinase
OM951_04025	COG2197	response regulator
OM951_04040	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
OM951_04065	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
OM951_04075	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
OM951_04090	COG1595	DNA-templated transcription, initiation
OM951_04100	COG1946	Acyl-CoA thioesterase
OM951_04115	COG0824	Thioesterase
OM951_04120	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
OM951_04125	COG0261	This protein binds to 23S rRNA in the presence of protein L20
OM951_04130	COG0211	Belongs to the bacterial ribosomal protein bL27 family
OM951_04135	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
OM951_04140	COG0268	Binds directly to 16S ribosomal RNA
OM951_04150	COG0196	riboflavin kinase activity
OM951_04155	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
OM951_04160	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
OM951_04165	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
OM951_04180	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
OM951_04185	COG1845	cytochrome c oxidase, subunit III
OM951_04190	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
OM951_04205	COG3152	Membrane
OM951_04215	COG2207	Transcriptional regulator
OM951_04240	COG1366	Belongs to the anti-sigma-factor antagonist family
OM951_04245	COG1366	Belongs to the anti-sigma-factor antagonist family
OM951_04250	COG2172	sigma factor antagonist activity
OM951_04275	COG4771	TonB-dependent receptor
OM951_04285	COG5507	3-demethylubiquinone-9 3-methyltransferase
OM951_04290	COG2205	protein histidine kinase activity
OM951_04300	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
OM951_04310	COG4191	Histidine kinase
OM951_04310	COG0784	Response regulator, receiver
OM951_04335	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
OM951_04345	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
OM951_04350	COG0228	four-way junction DNA binding
OM951_04355	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
OM951_04360	COG0336	Belongs to the RNA methyltransferase TrmD family
OM951_04365	COG0335	large ribosomal subunit rRNA binding
OM951_04370	COG0534	Mate efflux family protein
OM951_04395	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
OM951_04405	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
OM951_04410	COG2801	Transposase and inactivated derivatives
OM951_04445	COG1960	acyl-CoA dehydrogenase activity
OM951_04455	COG1309	transcriptional regulator
OM951_04460	COG4771	TonB-dependent receptor
OM951_04470	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
OM951_04475	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OM951_04480	COG0463	Glycosyl transferase, family 2
OM951_04485	COG0516	GMP reductase activity
OM951_04485	COG0517	IMP dehydrogenase activity
OM951_04490	COG2982	Protein involved in outer membrane biogenesis
OM951_04495	COG1272	protein, Hemolysin III
OM951_04500	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
OM951_04505	COG0739	heme binding
OM951_04510	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OM951_04515	COG0626	cystathionine gamma-synthase activity
OM951_04520	COG0460	homoserine dehydrogenase
OM951_04520	COG0527	aspartate kinase activity
OM951_04530	COG1760	l-serine dehydratase
OM951_04550	COG2353	YceI-like domain
OM951_04580	COG2814	Major facilitator Superfamily
OM951_04585	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
OM951_04595	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
OM951_04600	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
OM951_04605	COG0259	pyridoxamine-phosphate oxidase activity
OM951_04615	COG1842	Phage shock protein A
OM951_04640	COG0754	glutathionylspermidine amidase activity
OM951_04645	COG2814	Major facilitator Superfamily
OM951_04705	COG0531	amino acid
OM951_04710	COG2197	response regulator
OM951_04740	COG3328	transposase activity
OM951_04745	COG3328	transposase activity
OM951_04750	COG2801	Transposase and inactivated derivatives
OM951_04765	COG1113	amino acid transport
OM951_04775	COG1271	oxidase subunit
OM951_04845	COG2951	lytic endotransglycosylase activity
OM951_04860	COG0551	DNA topoisomerase type I activity
OM951_04860	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OM951_04910	COG1294	oxidase, subunit
OM951_04920	COG2239	Acts as a magnesium transporter
OM951_04930	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
OM951_04935	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
OM951_04945	COG1660	Displays ATPase and GTPase activities
OM951_04950	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
OM951_04955	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
OM951_04970	COG1137	ATPase activity
OM951_04975	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
OM951_04985	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
OM951_04995	COG0271	Belongs to the BolA IbaG family
OM951_05000	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
OM951_05020	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
OM951_05035	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
OM951_05045	COG0628	permease
OM951_05055	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
OM951_05070	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
OM951_05075	COG1555	photosystem II stabilization
OM951_05080	COG3328	transposase activity
OM951_05090	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
OM951_05095	COG1477	protein flavinylation
OM951_05120	COG3128	pkhd-type hydroxylase
OM951_05125	COG4774	siderophore transport
OM951_05130	COG2146	nitrite reductase [NAD(P)H] activity
OM951_05135	COG0456	acetyltransferase
OM951_05140	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
OM951_05145	COG0719	Fe-S assembly protein
OM951_05155	COG0719	Fe-S assembly protein
OM951_05160	COG1959	2 iron, 2 sulfur cluster binding
OM951_05170	COG0693	protein deglycase activity
OM951_05190	COG0739	heme binding
OM951_05205	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
OM951_05230	COG0519	Catalyzes the synthesis of GMP from XMP
OM951_05235	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
OM951_05240	COG1678	Uncharacterized ACR, COG1678
OM951_05245	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
OM951_05250	COG0540	Belongs to the ATCase OTCase family
OM951_05255	COG1764	response to oxidative stress
OM951_05265	COG0384	phenazine biosynthesis protein PhzF
OM951_05270	COG0384	phenazine biosynthesis protein PhzF
OM951_05275	COG0527	aspartate kinase activity
OM951_05290	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
OM951_05300	COG0142	geranyltranstransferase activity
OM951_05305	COG0629	single-stranded DNA binding
OM951_05310	COG3706	GGDEF domain
OM951_05310	COG5001	Diguanylate cyclase
OM951_05310	COG2203	Gaf domain
OM951_05310	COG4251	negative regulation of phosphorylation
OM951_05320	COG2080	2 iron, 2 sulfur cluster binding
OM951_05325	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
OM951_05330	COG1529	Aldehyde oxidase and xanthine dehydrogenase
OM951_05335	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
OM951_05375	COG2879	small protein
OM951_05380	COG1966	Carbon starvation protein
OM951_05385	COG1741	Belongs to the pirin family
OM951_05400	COG1741	Belongs to the pirin family
OM951_05410	COG1515	deoxyribonuclease V activity
OM951_05425	COG3590	peptidase
OM951_05435	COG2201	protein-glutamate methylesterase activity
OM951_05440	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
OM951_05445	COG2199	diguanylate cyclase activity
OM951_05445	COG2202	Pas domain
OM951_05445	COG2200	EAL domain
OM951_05450	COG0835	chemotaxis
OM951_05455	COG0840	transmembrane signaling receptor activity
OM951_05460	COG0643	Histidine kinase
OM951_05460	COG2198	Histidine kinase
OM951_05470	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
OM951_05485	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
OM951_05490	COG0745	RESPONSE REGULATOR receiver
OM951_05495	COG2205	protein histidine kinase activity
OM951_05510	COG4452	Inner membrane protein CreD
OM951_05535	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OM951_05540	COG0735	belongs to the Fur family
OM951_05555	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OM951_05565	COG1309	transcriptional regulator
OM951_05575	COG2207	Transcriptional regulator
OM951_05585	COG0583	DNA-binding transcription factor activity
OM951_05590	COG2814	Major facilitator Superfamily
OM951_05595	COG0667	Aldo Keto reductase
OM951_05710	COG1595	DNA-templated transcription, initiation
OM951_05720	COG5001	Diguanylate cyclase
OM951_05720	COG5002	protein histidine kinase activity
OM951_05725	COG1187	pseudouridine synthase activity
OM951_05745	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
OM951_05755	COG0475	glutathione-regulated potassium exporter activity
OM951_05760	COG5000	phosphorelay sensor kinase activity
OM951_05760	COG5002	protein histidine kinase activity
OM951_05765	COG0745	RESPONSE REGULATOR receiver
OM951_05795	COG1132	(ABC) transporter
OM951_05845	COG2155	Conserved Protein
OM951_05870	COG3118	belongs to the thioredoxin family
OM951_05880	COG0495	leucyl-tRNA aminoacylation
OM951_05910	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
OM951_05925	COG3328	transposase activity
OM951_05935	COG2968	Membrane
OM951_05940	COG0424	maF-like protein
OM951_05950	COG3164	Protein of unknown function
OM951_05960	COG0312	modulator of DNA gyrase
OM951_05965	COG3028	Belongs to the UPF0307 family
OM951_05970	COG0312	modulator of DNA gyrase
OM951_05980	COG4104	PAAR repeat-containing protein
OM951_05985	COG0142	geranyltranstransferase activity
OM951_05990	COG1722	exodeoxyribonuclease VII activity
OM951_05995	COG0037	tRNA processing
OM951_06000	COG1785	Belongs to the alkaline phosphatase family
OM951_06005	COG1301	dicarboxylic acid transport
OM951_06010	COG4106	trans-aconitate 2-methyltransferase activity
OM951_06020	COG0791	NLP P60 protein
OM951_06025	COG0791	NLP P60 protein
OM951_06030	COG1047	Peptidyl-prolyl cis-trans
OM951_06035	COG2311	Membrane
OM951_06040	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OM951_06045	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OM951_06100	COG0489	protein tyrosine kinase activity
OM951_06105	COG0717	Belongs to the dCTP deaminase family
OM951_06130	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
OM951_06135	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
OM951_06160	COG0433	COG0433 Predicted ATPase
OM951_06170	COG0688	phosphatidylethanolamine metabolic process
OM951_06180	COG2890	protein-(glutamine-N5) methyltransferase activity
OM951_06185	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
OM951_06190	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OM951_06195	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
OM951_06210	COG0101	tRNA pseudouridine synthase activity
OM951_06215	COG0135	phosphoribosylanthranilate isomerase activity
OM951_06225	COG0133	tryptophan synthase activity
OM951_06235	COG0159	tryptophan synthase activity
OM951_06240	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
OM951_06245	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OM951_06275	COG4221	oxidoreductase activity
OM951_06280	COG0149	triose-phosphate isomerase activity
OM951_06295	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OM951_06300	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OM951_06305	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OM951_06310	COG0649	NAD binding
OM951_06315	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
OM951_06320	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
OM951_06330	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
OM951_06335	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OM951_06360	COG1007	ATP synthesis coupled electron transport
OM951_06370	COG0779	Required for maturation of 30S ribosomal subunits
OM951_06375	COG0195	Participates in both transcription termination and antitermination
OM951_06380	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
OM951_06385	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
OM951_06390	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
OM951_06395	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
OM951_06400	COG1185	polyribonucleotide nucleotidyltransferase activity
OM951_06435	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
OM951_06445	COG2095	MarC family integral membrane protein
OM951_06455	COG1611	Belongs to the LOG family
OM951_06460	COG3275	phosphorelay sensor kinase activity
OM951_06605	COG3179	chitinase
OM951_06650	COG4695	Portal protein
OM951_06760	COG0556	nucleotide-excision repair
OM951_06775	COG3505	Type IV secretory pathway VirD4
OM951_06795	COG2948	multi-organism process
OM951_06815	COG3702	type iv secretory pathway
OM951_06860	COG0326	Molecular chaperone. Has ATPase activity
OM951_06865	COG0742	ribosomal rna small subunit methyltransferase
OM951_06870	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
OM951_06880	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
OM951_06885	COG0405	Gamma-glutamyltransferase
OM951_06890	COG3291	Pkd domain containing protein
OM951_06895	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
OM951_06930	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
OM951_06935	COG0343	queuine tRNA-ribosyltransferase activity
OM951_06940	COG1862	Preprotein translocase
OM951_06950	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OM951_06955	COG3328	transposase activity
OM951_06975	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OM951_06975	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OM951_06980	COG1105	Belongs to the carbohydrate kinase PfkB family
OM951_06985	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
OM951_06985	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
OM951_06990	COG1609	Transcriptional regulator
OM951_06995	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OM951_07000	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OM951_07010	COG2902	Dehydrogenase
OM951_07040	COG0840	transmembrane signaling receptor activity
OM951_07045	COG0477	Major facilitator Superfamily
OM951_07055	COG0784	Response regulator, receiver
OM951_07055	COG5002	protein histidine kinase activity
OM951_07055	COG2205	protein histidine kinase activity
OM951_07060	COG2733	membrane
OM951_07070	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
OM951_07080	COG2223	nitrite transmembrane transporter activity
OM951_07085	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
OM951_07090	COG0243	molybdopterin cofactor binding
OM951_07100	COG0477	Major facilitator Superfamily
OM951_07105	COG2703	oxygen carrier activity
OM951_07115	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OM951_07120	COG0174	glutamine synthetase
OM951_07125	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
OM951_07145	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
OM951_07165	COG3842	ATPase activity
OM951_07170	COG1176	ABC-type spermidine putrescine transport system, permease component I
OM951_07175	COG1177	transmembrane transport
OM951_07180	COG1012	belongs to the aldehyde dehydrogenase family
OM951_07195	COG4535	Mg2 and Co2 transporter CorC
OM951_07205	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
OM951_07215	COG1702	phosphate starvation-inducible protein PhoH
OM951_07220	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
OM951_07235	COG0741	lytic transglycosylase activity
OM951_07240	COG0723	plastoquinol--plastocyanin reductase activity
OM951_07245	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
OM951_07250	COG2857	Cytochrome c1
OM951_07255	COG0625	glutathione transferase activity
OM951_07260	COG2969	positive regulation of protein catabolic process
OM951_07290	COG0840	transmembrane signaling receptor activity
OM951_07295	COG0835	chemotaxis
OM951_07340	COG1262	PFAM Formylglycine-generating sulfatase enzyme
OM951_07350	COG1570	exodeoxyribonuclease VII activity
OM951_07355	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
OM951_07360	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
OM951_07360	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
OM951_07365	COG0802	atpase or kinase
OM951_07370	COG0860	N-Acetylmuramoyl-L-alanine amidase
OM951_07375	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
OM951_07400	COG1028	Short-chain dehydrogenase reductase Sdr
OM951_07405	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OM951_07410	COG0501	Belongs to the peptidase M48B family
OM951_07420	COG2081	HI0933 family
OM951_07425	COG4681	YaeQ
OM951_07435	COG0625	glutathione transferase activity
OM951_07445	COG3328	transposase activity
OM951_07470	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
OM951_07475	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
OM951_07480	COG0513	Belongs to the DEAD box helicase family
OM951_07485	COG0488	(ABC) transporter
OM951_07500	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
OM951_07505	COG0483	inositol monophosphate 1-phosphatase activity
OM951_07520	COG3300	MHYT domain
OM951_07520	COG5001	Diguanylate cyclase
OM951_07525	COG1509	lysine 2,3-aminomutase activity
OM951_07530	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
OM951_07540	COG0402	S-adenosylhomocysteine deaminase activity
OM951_07545	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
OM951_07575	COG3039	Transposase
OM951_07605	COG4302	ethanolamine ammonia-lyase activity
OM951_07620	COG3328	transposase activity
OM951_07635	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
OM951_07640	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
OM951_07660	COG2166	iron-sulfur cluster assembly
OM951_07665	COG0215	cysteine-tRNA ligase activity
OM951_07675	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
OM951_07680	COG0137	argininosuccinate synthase activity
OM951_07690	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
OM951_07695	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
OM951_07705	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
OM951_07710	COG0165	Argininosuccinate lyase
OM951_07720	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
OM951_07725	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
OM951_07755	COG1294	oxidase, subunit
OM951_07765	COG4988	ABC transporter
OM951_07770	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
OM951_07780	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OM951_07805	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
OM951_07825	COG4133	protoheme IX ABC transporter activity
OM951_07830	COG0436	Aminotransferase
OM951_07835	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OM951_07850	COG1187	pseudouridine synthase activity
OM951_07855	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
OM951_07860	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
OM951_07865	COG2350	Protein conserved in bacteria
OM951_07895	COG1175	transmembrane transport
OM951_07900	COG0395	ABC-type sugar transport system, permease component
OM951_07925	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OM951_07930	COG2957	Belongs to the agmatine deiminase family
OM951_07945	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
OM951_07950	COG0539	negative regulation of cytoplasmic translation
OM951_07955	COG0776	regulation of translation
OM951_07965	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
OM951_07970	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
OM951_07980	COG1210	Utp--glucose-1-phosphate uridylyltransferase
OM951_07985	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
OM951_07985	COG0475	glutathione-regulated potassium exporter activity
OM951_07995	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
OM951_08005	COG0518	GMP synthase (glutamine-hydrolyzing) activity
OM951_08005	COG0519	Catalyzes the synthesis of GMP from XMP
OM951_08035	COG3328	transposase activity
OM951_08050	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
OM951_08060	COG2801	Transposase and inactivated derivatives
OM951_08070	COG3384	dioxygenase
OM951_08075	COG0604	alcohol dehydrogenase
OM951_08085	COG3002	Belongs to the UPF0753 family
OM951_08090	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
OM951_08095	COG0583	DNA-binding transcription factor activity
OM951_08125	COG2197	response regulator
OM951_08140	COG1335	isochorismatase
OM951_08155	COG2814	Major facilitator Superfamily
OM951_08175	COG1914	H( )-stimulated, divalent metal cation uptake system
OM951_08190	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
OM951_08205	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
OM951_08220	COG1028	Short-chain dehydrogenase reductase Sdr
OM951_08225	COG1183	phosphatidylcholine synthase activity
OM951_08235	COG3243	poly(R)-hydroxyalkanoic acid synthase
OM951_08250	COG0723	plastoquinol--plastocyanin reductase activity
OM951_08250	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OM951_08260	COG2183	response to ionizing radiation
OM951_08265	COG2205	protein histidine kinase activity
OM951_08265	COG0784	Response regulator, receiver
OM951_08285	COG3328	transposase activity
OM951_08335	COG0800	Aldolase
OM951_08340	COG0129	dihydroxy-acid dehydratase activity
OM951_08345	COG0363	glucosamine-6-phosphate deaminase activity
OM951_08350	COG0837	glucose binding
OM951_08355	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
OM951_08365	COG0354	folic acid binding
OM951_08380	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
OM951_08395	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
OM951_08400	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
OM951_08410	COG4591	ABC-type transport system involved in lipoprotein release permease component
OM951_08415	COG1136	(ABC) transporter
OM951_08430	COG0811	peptide transport
OM951_08440	COG1132	(ABC) transporter
OM951_08445	COG1663	tetraacyldisaccharide 4'-kinase activity
OM951_08450	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
OM951_08455	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
OM951_08465	COG0322	excinuclease ABC activity
OM951_08470	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
OM951_08495	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
OM951_08515	COG1054	Belongs to the UPF0176 family
OM951_08525	COG3328	transposase activity
OM951_08530	COG3039	Transposase
OM951_08545	COG3064	Membrane
OM951_08550	COG0428	transporter
OM951_08560	COG2154	pterin-4-alpha-carbinolamine dehydratase
OM951_08600	COG0640	Transcriptional regulator
OM951_08725	COG3328	transposase activity
OM951_08745	COG1238	metal cluster binding
OM951_08805	COG4566	intracellular signal transduction
OM951_08815	COG5001	Diguanylate cyclase
OM951_08835	COG3685	Protein conserved in bacteria
OM951_08855	COG0243	molybdopterin cofactor binding
OM951_08865	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OM951_08870	COG2223	nitrite transmembrane transporter activity
OM951_08875	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OM951_08885	COG1648	precorrin-2 dehydrogenase activity
OM951_08885	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
OM951_08910	COG0746	molybdenum cofactor guanylyltransferase activity
OM951_08915	COG0303	'Molybdopterin
OM951_08925	COG0708	Exodeoxyribonuclease III
OM951_08940	COG3328	transposase activity
OM951_08975	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
OM951_08980	COG0303	'Molybdopterin
OM951_08985	COG1160	GTP binding
OM951_08990	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
OM951_09010	COG0820	rRNA (adenine-C2-)-methyltransferase activity
OM951_09025	COG1024	Enoyl-CoA hydratase
OM951_09025	COG1250	3-hydroxyacyl-CoA dehydrogenase
OM951_09030	COG0183	Belongs to the thiolase family
OM951_09035	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
OM951_09040	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
OM951_09050	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
OM951_09060	COG1674	ftsk spoiiie
OM951_09065	COG0492	ferredoxin-NADP+ reductase activity
OM951_09075	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
OM951_09085	COG0542	response to heat
OM951_09105	COG0482	sulfurtransferase activity
OM951_09110	COG2915	High frequency lysogenization protein hflD homolog
OM951_09130	COG4585	Histidine kinase
OM951_09140	COG5002	protein histidine kinase activity
OM951_09160	COG0784	Response regulator, receiver
OM951_09160	COG0835	chemotaxis
OM951_09170	COG1558	bacterial-type flagellum-dependent cell motility
OM951_09175	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
OM951_09185	COG4787	bacterial-type flagellum-dependent cell motility
OM951_09195	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
OM951_09200	COG1706	bacterial-type flagellum-dependent cell motility
OM951_09205	COG1705	Flagellar rod assembly protein muramidase FlgJ
OM951_09205	COG3951	Flagellar rod assembly protein muramidase FlgJ
OM951_09215	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
OM951_09225	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
OM951_09250	COG2197	response regulator
OM951_09260	COG2201	protein-glutamate methylesterase activity
OM951_09280	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OM951_09285	COG1028	Short-chain dehydrogenase reductase Sdr
OM951_09315	COG3328	transposase activity
OM951_09325	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
OM951_09350	COG1677	Flagellar hook-basal body complex protein FliE
OM951_09400	COG3190	flagellar
OM951_09420	COG1684	flagellar biosynthetic protein fliR
OM951_09430	COG3039	Transposase
OM951_09450	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
OM951_09480	COG0784	Response regulator, receiver
OM951_09480	COG2198	Histidine kinase
OM951_09480	COG0643	Histidine kinase
OM951_09500	COG3039	Transposase
OM951_09520	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
OM951_09525	COG1360	Flagellar Motor Protein
OM951_09530	COG1192	Involved in chromosome partitioning
OM951_09535	COG0835	chemotaxis
OM951_09545	COG0745	RESPONSE REGULATOR receiver
OM951_09560	COG0840	transmembrane signaling receptor activity
OM951_09565	COG0840	transmembrane signaling receptor activity
OM951_09580	COG0840	transmembrane signaling receptor activity
OM951_09590	COG0840	transmembrane signaling receptor activity
OM951_09595	COG0840	transmembrane signaling receptor activity
OM951_09600	COG0840	transmembrane signaling receptor activity
OM951_09605	COG0840	transmembrane signaling receptor activity
OM951_09620	COG0840	transmembrane signaling receptor activity
OM951_09625	COG0840	transmembrane signaling receptor activity
OM951_09630	COG0840	transmembrane signaling receptor activity
OM951_09635	COG0840	transmembrane signaling receptor activity
OM951_09640	COG0840	transmembrane signaling receptor activity
OM951_09650	COG0835	chemotaxis
OM951_09660	COG0840	transmembrane signaling receptor activity
OM951_09670	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
OM951_09675	COG2201	protein-glutamate methylesterase activity
OM951_09685	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OM951_09720	COG0318	PFAM AMP-dependent synthetase and ligase
OM951_09725	COG1024	Enoyl-CoA hydratase
OM951_09730	COG0784	Response regulator, receiver
OM951_09730	COG2198	Histidine kinase
OM951_09730	COG2205	protein histidine kinase activity
OM951_09735	COG0784	Response regulator, receiver
OM951_09735	COG2198	Histidine kinase
OM951_09735	COG2205	protein histidine kinase activity
OM951_09745	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
OM951_09750	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
OM951_09765	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
OM951_09775	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
OM951_09780	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
OM951_09790	COG0505	Belongs to the CarA family
OM951_09795	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
OM951_09800	COG2258	MOSC domain
OM951_09805	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OM951_09850	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
OM951_09870	COG0277	FAD linked oxidase domain protein
OM951_09875	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
OM951_09885	COG0531	amino acid
OM951_09890	COG0531	amino acid
OM951_09895	COG0235	Class ii aldolase
OM951_09900	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
OM951_09905	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
OM951_09920	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
OM951_09920	COG0140	phosphoribosyl-ATP diphosphatase activity
OM951_09925	COG0107	imidazoleglycerol-phosphate synthase activity
OM951_09930	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
OM951_09935	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
OM951_09940	COG0131	Imidazoleglycerol-phosphate dehydratase
OM951_09940	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
OM951_09945	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
OM951_09950	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
OM951_09955	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
OM951_09965	COG0124	histidyl-tRNA synthetase
OM951_09970	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OM951_10005	COG0460	homoserine dehydrogenase
OM951_10005	COG0527	aspartate kinase activity
OM951_10115	COG0531	amino acid
OM951_10130	COG0006	proline dipeptidase activity
OM951_10140	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OM951_10155	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OM951_10160	COG3938	Belongs to the proline racemase family
OM951_10170	COG0552	protein localization to endoplasmic reticulum
OM951_10175	COG1194	a g-specific adenine glycosylase
OM951_10210	COG0322	excinuclease ABC activity
OM951_10225	COG3040	lipid binding
OM951_10235	COG1960	acyl-CoA dehydrogenase activity
OM951_10245	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
OM951_10265	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OM951_10275	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OM951_10300	COG0438	transferase activity, transferring glycosyl groups
OM951_10310	COG0438	transferase activity, transferring glycosyl groups
OM951_10315	COG0438	transferase activity, transferring glycosyl groups
OM951_10365	COG0072	phenylalanine-tRNA ligase activity
OM951_10365	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OM951_10370	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
OM951_10385	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
OM951_10390	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
OM951_10405	COG2211	Major facilitator Superfamily
OM951_10415	COG1082	Xylose isomerase domain protein TIM barrel
OM951_10455	COG1012	belongs to the aldehyde dehydrogenase family
OM951_10470	COG0167	dihydroorotate dehydrogenase activity
OM951_10475	COG0812	UDP-N-acetylmuramate dehydrogenase activity
OM951_10480	COG0697	spore germination
OM951_10485	COG1794	racemase activity, acting on amino acids and derivatives
OM951_10500	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
OM951_10510	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
OM951_10515	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
OM951_10520	COG2203	Gaf domain
OM951_10520	COG3706	GGDEF domain
OM951_10520	COG4251	negative regulation of phosphorylation
OM951_10520	COG5001	Diguanylate cyclase
OM951_10530	COG1472	Belongs to the glycosyl hydrolase 3 family
OM951_10550	COG0166	Belongs to the GPI family
OM951_10555	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
OM951_10560	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
OM951_10565	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
OM951_10590	COG1469	GTP cyclohydrolase I activity
OM951_10595	COG3328	transposase activity
OM951_10610	COG0477	Major facilitator Superfamily
OM951_10615	COG2115	Belongs to the xylose isomerase family
OM951_10620	COG1070	Carbohydrate kinase
OM951_10630	COG1501	Belongs to the glycosyl hydrolase 31 family
OM951_10665	COG0800	Aldolase
OM951_10670	COG4948	Mandelate Racemase Muconate Lactonizing
OM951_10680	COG3734	2-keto-3-deoxy-galactonokinase
OM951_10685	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
OM951_10695	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OM951_10710	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
OM951_10715	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
OM951_10730	COG0351	phosphomethylpyrimidine kinase
OM951_10755	COG0583	DNA-binding transcription factor activity
OM951_10760	COG1741	Belongs to the pirin family
OM951_10770	COG0582	viral genome integration into host DNA
OM951_10825	COG1196	nuclear chromosome segregation
OM951_10910	COG3179	chitinase
OM951_10965	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
OM951_11125	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
OM951_11130	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
OM951_11135	COG2137	regulation of response to DNA damage stimulus
OM951_11140	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
OM951_11145	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
OM951_11155	COG1546	Belongs to the CinA family
OM951_11160	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
OM951_11170	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
OM951_11175	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
OM951_11185	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
OM951_11190	COG1534	Rna-binding protein
OM951_11195	COG3737	Protein of unknown function (DUF498/DUF598)
OM951_11205	COG1238	metal cluster binding
OM951_11210	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
OM951_11215	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
OM951_11220	COG2840	Smr protein MutS2
OM951_11225	COG0585	pseudouridine synthase activity
OM951_11230	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
OM951_11240	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
OM951_11245	COG0148	phosphopyruvate hydratase activity
OM951_11255	COG2877	3-deoxy-8-phosphooctulonate synthase activity
OM951_11260	COG0504	CTP synthase activity
OM951_11285	COG0306	phosphate transporter
OM951_11295	COG1253	flavin adenine dinucleotide binding
OM951_11310	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OM951_11325	COG1136	(ABC) transporter
OM951_11340	COG0438	transferase activity, transferring glycosyl groups
OM951_11350	COG2264	protein methyltransferase activity
OM951_11380	COG2244	polysaccharide biosynthetic process
OM951_11430	COG1595	DNA-templated transcription, initiation
OM951_11445	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
OM951_11455	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
OM951_11465	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OM951_11485	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
OM951_11490	COG4191	Histidine kinase
OM951_11490	COG0784	Response regulator, receiver
OM951_11510	COG0840	transmembrane signaling receptor activity
OM951_11535	COG0583	DNA-binding transcription factor activity
OM951_11540	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
OM951_11545	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
OM951_11560	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
OM951_11565	COG0077	Prephenate dehydratase
OM951_11565	COG1605	Chorismate mutase
OM951_11570	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
OM951_11575	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
OM951_11580	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
OM951_11620	COG1228	amidohydrolase
OM951_11625	COG2986	histidine ammonia-lyase
OM951_11635	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
OM951_11645	COG4993	Dehydrogenase
OM951_11655	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
OM951_11665	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
OM951_11670	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
OM951_11675	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
OM951_11685	COG3115	cell septum assembly
OM951_11695	COG0359	binds to the 23S rRNA
OM951_11700	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
OM951_11705	COG0360	Binds together with S18 to 16S ribosomal RNA
OM951_11710	COG0316	Belongs to the HesB IscA family
OM951_11715	COG0017	Asparaginyl-tRNA synthetase
OM951_11795	COG0288	reversible hydration of carbon dioxide
OM951_11800	COG0662	Cupin 2, conserved barrel domain protein
OM951_11810	COG3844	kynureninase activity
OM951_11815	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OM951_11825	COG2925	Exonuclease
OM951_11845	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
OM951_11850	COG0116	Belongs to the methyltransferase superfamily
OM951_11850	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
OM951_11860	COG0488	(ABC) transporter
OM951_11895	COG0494	nUDIX hydrolase
OM951_11905	COG1024	Enoyl-CoA hydratase
OM951_11915	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
OM951_11920	COG0659	secondary active sulfate transmembrane transporter activity
OM951_11945	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
OM951_11950	COG0573	inorganic phosphate transmembrane transporter activity
OM951_11955	COG0581	inorganic phosphate transmembrane transporter activity
OM951_11960	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
OM951_11965	COG0704	Plays a role in the regulation of phosphate uptake
OM951_11975	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
OM951_11985	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OM951_11995	COG0557	exoribonuclease II activity
OM951_12010	COG1960	acyl-CoA dehydrogenase activity
OM951_12015	COG2226	methyltransferase
OM951_12020	COG0646	methionine synthase
OM951_12020	COG1410	methionine synthase
OM951_12025	COG0646	methionine synthase
OM951_12025	COG1410	methionine synthase
OM951_12035	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OM951_12065	COG2900	Belongs to the SlyX family
OM951_12080	COG0386	Belongs to the glutathione peroxidase family
OM951_12090	COG1725	Transcriptional regulator
OM951_12095	COG1131	(ABC) transporter
OM951_12145	COG2850	peptidyl-arginine hydroxylation
OM951_12180	COG1132	(ABC) transporter
OM951_12185	COG0583	DNA-binding transcription factor activity
OM951_12215	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
OM951_12220	COG0484	heat shock protein binding
OM951_12225	COG0443	Heat shock 70 kDa protein
OM951_12230	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
OM951_12235	COG1420	regulation of RNA biosynthetic process
OM951_12240	COG0497	DNA recombination
OM951_12250	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
OM951_12265	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
OM951_12290	COG3706	GGDEF domain
OM951_12335	COG0583	DNA-binding transcription factor activity
OM951_12350	COG0415	Belongs to the DNA photolyase family
OM951_12355	COG0305	Participates in initiation and elongation during chromosome replication
OM951_12365	COG0367	asparagine synthase
OM951_12380	COG1960	acyl-CoA dehydrogenase activity
OM951_12395	COG0084	hydrolase, TatD family'
OM951_12400	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
OM951_12460	COG0386	Belongs to the glutathione peroxidase family
OM951_12465	COG0339	signal peptide processing
OM951_12495	COG3104	oligopeptide transport
OM951_12525	COG2814	Major facilitator Superfamily
OM951_12530	COG1566	PFAM secretion protein HlyD family protein
OM951_12565	COG3328	transposase activity
OM951_12570	COG2801	Transposase and inactivated derivatives
OM951_12600	COG3328	transposase activity
OM951_12625	COG4774	siderophore transport
OM951_12635	COG0367	asparagine synthase
OM951_12645	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
OM951_12650	COG1393	Belongs to the ArsC family
OM951_12700	COG0052	Belongs to the universal ribosomal protein uS2 family
OM951_12705	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
OM951_12715	COG0528	UMP kinase activity
OM951_12720	COG0233	cytoplasmic translational termination
OM951_12725	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
OM951_12730	COG0575	Belongs to the CDS family
OM951_12735	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
OM951_12740	COG0750	zinc metalloprotease
OM951_12755	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
OM951_12760	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
OM951_12765	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
OM951_12770	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
OM951_12785	COG0825	malonyl-CoA metabolic process
OM951_12800	COG1981	membrane
OM951_12820	COG1695	Transcriptional regulator
OM951_12840	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
OM951_12850	COG2040	homocysteine
OM951_12855	COG0833	amino acid
OM951_12870	COG0346	lactoylglutathione lyase activity
OM951_12890	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OM951_12890	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OM951_12900	COG2878	Part of a membrane complex involved in electron transport
OM951_12915	COG1595	DNA-templated transcription, initiation
OM951_12940	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
OM951_12955	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
OM951_12960	COG0251	oxidation-reduction process
OM951_12970	COG0392	lysyltransferase activity
OM951_12970	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
OM951_13005	COG2814	Major facilitator Superfamily
OM951_13010	COG1902	pentaerythritol trinitrate reductase activity
OM951_13020	COG2824	Alkylphosphonate utilization operon protein PhnA
OM951_13030	COG1047	Peptidyl-prolyl cis-trans
OM951_13035	COG1077	Cell shape determining protein MreB Mrl
OM951_13050	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
OM951_13060	COG5487	UPF0391 membrane protein
OM951_13065	COG1451	nucleotide metabolic process
OM951_13085	COG0183	Belongs to the thiolase family
OM951_13120	COG1793	dna ligase
OM951_13120	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
OM951_13130	COG1793	dna ligase
OM951_13135	COG1201	RNA secondary structure unwinding
OM951_13145	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OM951_13150	COG1278	Cold shock
OM951_13160	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
OM951_13165	COG1472	Belongs to the glycosyl hydrolase 3 family
OM951_13170	COG3046	protein related to deoxyribodipyrimidine photolyase
OM951_13175	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
OM951_13180	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
OM951_13185	COG2954	triphosphatase activity
OM951_13190	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
OM951_13200	COG1381	Involved in DNA repair and RecF pathway recombination
OM951_13205	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
OM951_13210	COG0571	ribonuclease III activity
OM951_13225	COG0481	GTPase activity
OM951_13230	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OM951_13245	COG1024	Enoyl-CoA hydratase
OM951_13245	COG1250	3-hydroxyacyl-CoA dehydrogenase
OM951_13255	COG0457	Tetratricopeptide repeat
OM951_13265	COG0457	Tetratricopeptide repeat
OM951_13295	COG1960	acyl-CoA dehydrogenase activity
OM951_13315	COG3867	Arabinogalactan endo-beta-1,4-galactanase
OM951_13320	COG3250	beta-galactosidase activity
OM951_13365	COG2801	Transposase and inactivated derivatives
OM951_13375	COG3328	transposase activity
OM951_13400	COG0509	glycine decarboxylation via glycine cleavage system
OM951_13405	COG0404	The glycine cleavage system catalyzes the degradation of glycine
OM951_13415	COG0330	HflC and HflK could
OM951_13420	COG1742	UPF0060 membrane protein
OM951_13425	COG3956	TIGRFAM MazG family protein
OM951_13435	COG0494	nUDIX hydrolase
OM951_13445	COG1385	rRNA (uridine-N3-)-methyltransferase activity
OM951_13450	COG0837	glucose binding
OM951_13470	COG1388	LysM domain
OM951_13470	COG3858	chitin binding
OM951_13475	COG3525	Glycosyl hydrolase, family 20, catalytic domain
OM951_13485	COG1472	Belongs to the glycosyl hydrolase 3 family
OM951_13495	COG3537	Alpha-1,2-mannosidase
OM951_13530	COG3142	Participates in the control of copper homeostasis
OM951_13535	COG1446	asparaginase
OM951_13560	COG0784	Response regulator, receiver
OM951_13560	COG0643	Histidine kinase
OM951_13560	COG2198	Histidine kinase
OM951_13565	COG0840	transmembrane signaling receptor activity
OM951_13570	COG0835	chemotaxis
OM951_13585	COG0189	ligase activity
OM951_13595	COG1397	ADP-ribosylglycohydrolase
OM951_13605	COG1199	ATP-dependent helicase activity
OM951_13615	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OM951_13620	COG1215	transferase activity, transferring glycosyl groups
OM951_13630	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
OM951_13645	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
OM951_13650	COG0535	radical SAM domain protein
OM951_13655	COG0535	radical SAM domain protein
OM951_13670	COG0837	glucose binding
OM951_13690	COG1643	Atp-dependent helicase
OM951_13695	COG0783	Belongs to the Dps family
OM951_13700	COG0514	ATP-dependent DNA helicase (RecQ)
OM951_13740	COG0840	transmembrane signaling receptor activity
OM951_13760	COG3920	Histidine kinase
OM951_13765	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
OM951_13775	COG0602	queuosine metabolic process
OM951_13785	COG2885	chlorophyll binding
OM951_13790	COG0823	Involved in the tonB-independent uptake of proteins
OM951_13800	COG0848	biopolymer transport protein
OM951_13810	COG0824	Thioesterase
OM951_13815	COG2255	four-way junction helicase activity
OM951_13825	COG3158	transport of potassium into the cell
OM951_13830	COG0632	four-way junction helicase activity
OM951_13835	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
OM951_13840	COG0217	transcriptional regulatory protein
OM951_13855	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
OM951_13870	COG0477	Major facilitator Superfamily
OM951_13890	COG0657	acetylesterase activity
OM951_13890	COG2755	lipolytic protein G-D-S-L family
OM951_13910	COG0488	(ABC) transporter
OM951_13940	COG4651	solute:proton antiporter activity
OM951_13940	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
OM951_13965	COG4772	TonB-dependent receptor
OM951_13975	COG4264	IucA IucC family
OM951_13990	COG0019	diaminopimelate decarboxylase activity
OM951_14010	COG3328	transposase activity
OM951_14030	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
OM951_14040	COG1492	cobalamin metabolic process
OM951_14050	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
OM951_14075	COG4206	TonB-dependent receptor
OM951_14085	COG0542	response to heat
OM951_14130	COG1877	trehalose-phosphatase activity
OM951_14135	COG3387	PFAM Glycoside hydrolase 15-related
OM951_14155	COG0840	transmembrane signaling receptor activity
OM951_14160	COG3011	Protein conserved in bacteria
OM951_14175	COG0564	pseudouridine synthase activity
OM951_14180	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
OM951_14190	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
OM951_14190	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OM951_14200	COG3328	transposase activity
OM951_14215	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
OM951_14220	COG0045	succinate-CoA ligase (ADP-forming) activity
OM951_14265	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
OM951_14270	COG0237	dephospho-CoA kinase activity
OM951_14295	COG0745	RESPONSE REGULATOR receiver
OM951_14305	COG0189	ligase activity
OM951_14320	COG3328	transposase activity
OM951_14345	COG2801	Transposase and inactivated derivatives
OM951_14375	COG3328	transposase activity
OM951_14380	COG0322	excinuclease ABC activity
OM951_14420	COG2801	Transposase and inactivated derivatives
OM951_14445	COG3039	Transposase
OM951_14450	COG3039	Transposase
OM951_14490	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
OM951_14495	COG1061	Type III restriction enzyme res subunit
OM951_14570	COG2022	thiamine diphosphate biosynthetic process
OM951_14575	COG0220	tRNA (guanine-N7-)-methyltransferase activity
OM951_14580	COG0471	metal ion transport
OM951_14580	COG3273	potassium ion transport
OM951_14605	COG1970	mechanosensitive ion channel activity
OM951_14615	COG1609	Transcriptional regulator
OM951_14630	COG4948	Mandelate Racemase Muconate Lactonizing
OM951_14640	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OM951_14650	COG0308	aminopeptidase N
OM951_14655	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OM951_14665	COG0529	Catalyzes the synthesis of activated sulfate
OM951_14665	COG2895	sulfate adenylyltransferase (ATP) activity
OM951_14670	COG0175	sulfate reduction
OM951_14675	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
OM951_14680	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OM951_14685	COG0175	sulfate reduction
OM951_14705	COG2198	Histidine kinase
OM951_14705	COG2205	protein histidine kinase activity
OM951_14705	COG0784	Response regulator, receiver
OM951_14720	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
OM951_14720	COG1648	precorrin-2 dehydrogenase activity
OM951_14735	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
OM951_14740	COG3588	fructose-bisphosphate aldolase
OM951_14745	COG0469	pyruvate kinase activity
OM951_14755	COG0126	phosphoglycerate kinase activity
OM951_14785	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
OM951_14795	COG3047	cAMP biosynthetic process
OM951_14810	COG3453	Protein conserved in bacteria
OM951_14810	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OM951_14815	COG0725	ABC transporter, periplasmic molybdate-binding protein
OM951_14820	COG4149	molybdate abc transporter
OM951_14825	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
OM951_14845	COG0642	Histidine kinase
OM951_14870	COG1022	Amp-dependent synthetase and ligase
OM951_14895	COG1376	ErfK ybiS ycfS ynhG family protein
OM951_14900	COG0739	heme binding
OM951_14905	COG4773	Receptor
OM951_14920	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
OM951_14925	COG1301	dicarboxylic acid transport
OM951_14935	COG2304	oxidoreductase activity
OM951_14955	COG0714	Associated with various cellular activities
OM951_14985	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
OM951_15005	COG1957	nucleoside hydrolase
OM951_15010	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
OM951_15020	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
OM951_15035	COG1561	YicC-like family, N-terminal region
OM951_15040	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
OM951_15050	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
OM951_15055	COG0635	Involved in the biosynthesis of porphyrin-containing compound
OM951_15070	COG0006	proline dipeptidase activity
OM951_15080	COG0006	proline dipeptidase activity
OM951_15085	COG3079	Belongs to the UPF0149 family
OM951_15105	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
OM951_15125	COG2912	Transglutaminase-like superfamily
OM951_15135	COG1773	rubredoxin
OM951_15140	COG0352	thiamine-phosphate diphosphorylase activity
OM951_15160	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
OM951_15170	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
OM951_15175	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
OM951_15215	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
OM951_15220	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OM951_15225	COG1028	Short-chain dehydrogenase reductase Sdr
OM951_15235	COG0671	phosphoesterase, PA-phosphatase related
OM951_15245	COG3781	membrane
OM951_15255	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
OM951_15260	COG0563	adenylate kinase activity
OM951_15275	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
OM951_15285	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
OM951_15305	COG3710	Transcriptional regulator
OM951_15310	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
OM951_15320	COG0840	transmembrane signaling receptor activity
OM951_15325	COG0405	Gamma-glutamyltransferase
OM951_15330	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
OM951_15355	COG0473	3-isopropylmalate dehydrogenase activity
OM951_15360	COG0066	3-isopropylmalate dehydratase activity
OM951_15365	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
OM951_15385	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
OM951_15390	COG1538	Outer membrane efflux protein
OM951_15395	COG1519	Transferase
OM951_15400	COG1560	Kdo2-lipid A biosynthetic process
OM951_15425	COG0280	phosphate acetyltransferase
OM951_15425	COG0281	malic enzyme
OM951_15460	COG2801	Transposase and inactivated derivatives
OM951_15470	COG0583	DNA-binding transcription factor activity
OM951_15475	COG0667	Aldo Keto reductase
OM951_15490	COG2197	response regulator
OM951_15500	COG0642	Histidine kinase
OM951_15515	COG2851	Citrate transporter
OM951_15520	COG1028	Short-chain dehydrogenase reductase Sdr
OM951_15525	COG1609	Transcriptional regulator
OM951_15530	COG2211	Major facilitator Superfamily
OM951_15555	COG1162	GTPase activity
OM951_15560	COG0436	Aminotransferase
OM951_15575	COG0726	polysaccharide deacetylase
OM951_15580	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
OM951_15595	COG3964	amidohydrolase
OM951_15600	COG0402	S-adenosylhomocysteine deaminase activity
OM951_15625	COG1307	EDD domain protein, DegV family
OM951_15640	COG2801	Transposase and inactivated derivatives
OM951_15650	COG3791	Glutathione-dependent formaldehyde-activating
OM951_15680	COG2205	protein histidine kinase activity
OM951_15695	COG0218	Necessary for normal cell division and for the maintenance of normal septation
OM951_15710	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
OM951_15720	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
OM951_15725	COG1012	belongs to the aldehyde dehydrogenase family
OM951_15730	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
OM951_15755	COG1183	phosphatidylcholine synthase activity
OM951_15765	COG0442	prolyl-tRNA aminoacylation
OM951_15780	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
OM951_15785	COG1127	ABC transporter
OM951_15790	COG3218	ABC-type transport auxiliary lipoprotein component
OM951_15790	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
OM951_15820	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OM951_15825	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
OM951_15825	COG0662	Cupin 2, conserved barrel domain protein
OM951_15855	COG2086	electron transfer activity
OM951_15870	COG0546	phosphoglycolate phosphatase activity
OM951_15870	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
OM951_15875	COG0277	FAD linked oxidase domain protein
OM951_15885	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OM951_15910	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OM951_15915	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
OM951_15920	COG0438	transferase activity, transferring glycosyl groups
OM951_15940	COG0438	transferase activity, transferring glycosyl groups
OM951_15945	COG0626	cystathionine gamma-synthase activity
OM951_15975	COG0625	glutathione transferase activity
OM951_15985	COG0513	Belongs to the DEAD box helicase family
OM951_15990	COG0720	synthase
OM951_16000	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
OM951_16010	COG1956	GAF domain-containing protein
OM951_16025	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OM951_16030	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
OM951_16040	COG4991	sh3 domain protein
OM951_16050	COG0339	signal peptide processing
OM951_16065	COG2132	Multicopper oxidase
OM951_16100	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
OM951_16105	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OM951_16110	COG1136	(ABC) transporter
OM951_16115	COG0577	efflux transmembrane transporter activity
OM951_16115	COG1136	(ABC) transporter
OM951_16135	COG4191	Histidine kinase
OM951_16140	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
OM951_16165	COG0355	proton-transporting ATP synthase activity, rotational mechanism
OM951_16170	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
OM951_16175	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
OM951_16180	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
OM951_16185	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
OM951_16200	COG0356	it plays a direct role in the translocation of protons across the membrane
OM951_16220	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OM951_16230	COG0508	dehydrogenase complex catalyzes the overall conversion of
OM951_16270	COG2011	ABC-type metal ion transport system permease component
OM951_16275	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
OM951_16280	COG0697	spore germination
OM951_16285	COG1666	GTP binding
OM951_16295	COG2198	Histidine kinase
OM951_16295	COG0784	Response regulator, receiver
OM951_16295	COG5002	protein histidine kinase activity
OM951_16320	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OM951_16325	COG1187	pseudouridine synthase activity
OM951_16330	COG2813	Specifically methylates the guanine in position
OM951_16335	COG3039	Transposase
OM951_16350	COG3328	transposase activity
OM951_16365	COG2205	protein histidine kinase activity
OM951_16365	COG2202	Pas domain
OM951_16385	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
OM951_16390	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OM951_16445	COG0842	Transport permease protein
OM951_16450	COG1131	(ABC) transporter
OM951_16455	COG0025	NhaP-type Na H and K H
OM951_16460	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
OM951_16465	COG1573	uracil-dna glycosylase
OM951_16475	COG3384	dioxygenase
OM951_16485	COG0583	DNA-binding transcription factor activity
OM951_16495	COG0667	Aldo Keto reductase
OM951_16510	COG3590	peptidase
OM951_16530	COG0531	amino acid
OM951_16545	COG2972	Histidine kinase
OM951_16565	COG3685	Protein conserved in bacteria
OM951_16570	COG3546	catalase activity
OM951_16620	COG1271	oxidase subunit
OM951_16625	COG1294	oxidase, subunit
OM951_16640	COG1028	Short-chain dehydrogenase reductase Sdr
OM951_16660	COG1063	alcohol dehydrogenase
OM951_16735	COG0251	oxidation-reduction process
OM951_16765	COG0659	secondary active sulfate transmembrane transporter activity
OM951_16770	COG0038	chloride channel
OM951_16780	COG0024	Methionine aminopeptidase
OM951_16815	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OM951_16820	COG1490	D-aminoacyl-tRNA deacylase activity
OM951_16825	COG1560	Kdo2-lipid A biosynthetic process
OM951_16870	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
OM951_16870	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
OM951_16875	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
OM951_16880	COG0242	peptide deformylase activity
OM951_16885	COG1652	LysM domain
OM951_16890	COG0758	DNA mediated transformation
OM951_16910	COG1754	DNA topoisomerase type I activity
OM951_16910	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OM951_16915	COG0009	L-threonylcarbamoyladenylate synthase
OM951_16930	COG1028	Short-chain dehydrogenase reductase Sdr
OM951_16940	COG0616	signal peptide processing
OM951_16945	COG0534	Mate efflux family protein
OM951_16970	COG0625	glutathione transferase activity
OM951_16985	COG1252	NADH dehydrogenase
OM951_16990	COG2860	membrane
OM951_16995	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OM951_17000	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
OM951_17005	COG2201	protein-glutamate methylesterase activity
OM951_17010	COG2177	Part of the ABC transporter FtsEX involved in
OM951_17015	COG2884	Cell division ATP-binding protein ftsE
OM951_17025	COG3118	belongs to the thioredoxin family
OM951_17030	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
OM951_17040	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
OM951_17065	COG1652	LysM domain
OM951_17070	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
OM951_17070	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
OM951_17075	COG1473	amidohydrolase
OM951_17080	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OM951_17085	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OM951_17095	COG5383	Protein conserved in bacteria
OM951_17130	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
OM951_17135	COG3023	N-Acetylmuramoyl-L-alanine amidase
OM951_17145	COG4948	Mandelate Racemase Muconate Lactonizing
OM951_17155	COG0531	amino acid
OM951_17170	COG4682	membrane
OM951_17175	COG2133	pyrroloquinoline quinone binding
OM951_17185	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
OM951_17190	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
OM951_17205	COG1610	YqeY-like protein
OM951_17210	COG1295	ribonuclease BN
OM951_17215	COG0358	DNA primase activity
OM951_17230	COG0109	protoheme IX farnesyltransferase activity
OM951_17260	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
OM951_17275	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
OM951_17315	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
OM951_17320	COG0739	heme binding
OM951_17325	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
OM951_17335	COG2223	nitrite transmembrane transporter activity
OM951_17340	COG0708	Exodeoxyribonuclease III
OM951_17345	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
OM951_17355	COG1192	Involved in chromosome partitioning
OM951_17360	COG1475	DNA binding
OM951_17375	COG0463	Glycosyl transferase, family 2
OM951_17395	COG0756	dUTP diphosphatase activity
OM951_17400	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
OM951_17405	COG2003	Belongs to the UPF0758 family
OM951_17410	COG0018	arginyl-trna synthetase
OM951_17425	COG4221	oxidoreductase activity
OM951_17430	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
OM951_17430	COG2755	lipolytic protein G-D-S-L family
OM951_17440	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OM951_17445	COG1166	arginine decarboxylase activity
OM951_17450	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
OM951_17470	COG3291	Pkd domain containing protein
OM951_17470	COG3525	Glycosyl hydrolase, family 20, catalytic domain
OM951_17485	COG0606	chelatase, subunit chli
OM951_17500	COG4943	cyclic-guanylate-specific phosphodiesterase activity
OM951_17525	COG1690	Belongs to the RtcB family
OM951_17565	COG1090	epimerase
OM951_17575	COG0642	Histidine kinase
OM951_17595	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OM951_17620	COG1011	Hydrolase
OM951_17625	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
OM951_17640	COG0753	catalase activity
OM951_17655	COG2197	response regulator
OM951_17660	COG4585	Histidine kinase
OM951_17665	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OM951_17670	COG1136	(ABC) transporter
OM951_17695	COG0697	spore germination
OM951_17720	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OM951_17725	COG0180	Tryptophanyl-tRNA synthetase
OM951_17730	COG3237	CsbD-like
OM951_17770	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
OM951_17785	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
OM951_17790	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
OM951_17790	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
OM951_17800	COG3228	Belongs to the MtfA family
OM951_17830	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OM951_17875	COG1199	ATP-dependent helicase activity
OM951_17890	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
OM951_17980	COG4555	ABC transporter
OM951_17990	COG1476	TRANSCRIPTIONal
OM951_18010	COG1230	cation diffusion facilitator family transporter
OM951_18015	COG0543	2 iron, 2 sulfur cluster binding
OM951_18015	COG0633	Ferredoxin
OM951_18020	COG2801	Transposase and inactivated derivatives
OM951_18030	COG1131	(ABC) transporter
OM951_18035	COG0842	Transport permease protein
OM951_18040	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
OM951_18065	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OM951_18085	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OM951_18090	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OM951_18105	COG1042	CoA-binding domain protein
OM951_18105	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OM951_18105	COG0045	succinate-CoA ligase (ADP-forming) activity
OM951_18110	COG2239	Acts as a magnesium transporter
OM951_18115	COG3338	carbonate dehydratase activity
OM951_18130	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
OM951_18135	COG3387	PFAM Glycoside hydrolase 15-related
OM951_18150	COG3100	YcgL domain-containing protein
OM951_18155	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
OM951_18175	COG1028	Short-chain dehydrogenase reductase Sdr
OM951_18235	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OM951_18270	COG0408	coproporphyrinogen oxidase activity
OM951_18310	COG0631	protein serine/threonine phosphatase activity
OM951_18335	COG0667	Aldo Keto reductase
OM951_18340	COG0583	DNA-binding transcription factor activity
OM951_18415	COG0154	amidase activity
OM951_18440	COG3328	transposase activity
OM951_18520	COG0210	DNA helicase
OM951_18535	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OM951_18540	COG0583	DNA-binding transcription factor activity
OM951_18545	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
OM951_18555	COG2159	amidohydrolase
OM951_18580	COG3328	transposase activity
OM951_18585	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OM951_18605	COG0357	Ribosomal RNA small subunit methyltransferase G
OM951_18610	COG3540	Alkaline phosphatase
OM951_18620	COG2091	lysine biosynthetic process via aminoadipic acid
OM951_18635	COG0708	Exodeoxyribonuclease III
OM951_18640	COG1940	carbohydrate kinase activity
OM951_18640	COG1846	Transcriptional regulator
OM951_18650	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
OM951_18660	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OM951_18665	COG3162	membrane
OM951_18675	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OM951_18705	COG3507	Belongs to the glycosyl hydrolase 43 family
OM951_18725	COG1028	Short-chain dehydrogenase reductase Sdr
OM951_18730	COG0179	Fumarylacetoacetate (FAA) hydrolase
OM951_18735	COG4948	Mandelate Racemase Muconate Lactonizing
OM951_18740	COG3254	rhamnose metabolic process
OM951_18745	COG0738	Major facilitator superfamily
OM951_18750	COG1414	Transcriptional regulator
OM951_18755	COG2207	Transcriptional regulator
OM951_18755	COG1917	Cupin 2, conserved barrel domain protein
OM951_18765	COG1971	Probably functions as a manganese efflux pump
OM951_18770	COG2205	protein histidine kinase activity
OM951_18780	COG3459	Glycosyltransferase 36 associated
OM951_18785	COG2211	Major facilitator Superfamily
OM951_18790	COG3265	gluconokinase activity
OM951_18795	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
OM951_18815	COG2911	Protein conserved in bacteria
OM951_18820	COG0729	surface antigen
OM951_18825	COG4771	TonB-dependent receptor
OM951_18830	COG0457	Tetratricopeptide repeat
OM951_18840	COG0752	glycyl-tRNA synthetase alpha subunit
OM951_18845	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
OM951_18860	COG0518	GMP synthase (glutamine-hydrolyzing) activity
OM951_18860	COG0519	Catalyzes the synthesis of GMP from XMP
OM951_18875	COG0805	protein transport
OM951_18880	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
OM951_18885	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
OM951_18895	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
OM951_18915	COG2974	May be involved in recombination
OM951_18920	COG0037	tRNA processing
OM951_18925	COG2115	Belongs to the xylose isomerase family
OM951_18935	COG3661	Belongs to the glycosyl hydrolase 67 family
OM951_18945	COG4948	Mandelate Racemase Muconate Lactonizing
OM951_18960	COG0246	Mannitol dehydrogenase
OM951_19015	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
OM951_19040	COG3386	PFAM SMP-30 Gluconolaconase
OM951_19055	COG1904	glucuronate isomerase
OM951_19060	COG3693	PFAM glycoside hydrolase, family 10
OM951_19070	COG3039	Transposase
OM951_19080	COG3693	PFAM glycoside hydrolase, family 10
OM951_19095	COG2211	Major facilitator Superfamily
OM951_19110	COG3328	transposase activity
OM951_19155	COG2937	Belongs to the GPAT DAPAT family
OM951_19185	COG0284	orotidine-5'-phosphate decarboxylase activity
OM951_19190	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
OM951_19205	COG0635	Involved in the biosynthesis of porphyrin-containing compound
OM951_19255	COG0210	DNA helicase
OM951_19260	COG1435	thymidine kinase activity
OM951_19270	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
OM951_19280	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
OM951_19310	COG3135	benzoate transporter
OM951_19335	COG0676	glucose-6-phosphate 1-epimerase activity
OM951_19345	COG3012	SEC-C Motif Domain Protein
OM951_19350	COG3328	transposase activity
OM951_19370	COG0302	gtp cyclohydrolase
OM951_19385	COG1566	PFAM secretion protein HlyD family protein
OM951_19395	COG1289	transmembrane transporter activity
OM951_19400	COG0477	Major facilitator Superfamily
OM951_19410	COG0583	DNA-binding transcription factor activity
OM951_19415	COG4221	oxidoreductase activity
OM951_19425	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OM951_19480	COG0564	pseudouridine synthase activity
OM951_19510	COG3012	SEC-C Motif Domain Protein
OM951_19580	COG4790	Type iii secretion
OM951_19735	COG3039	Transposase
OM951_19755	COG2801	Transposase and inactivated derivatives
OM951_19765	COG0511	ligase activity, forming carbon-carbon bonds
OM951_19770	COG0439	Biotin carboxylase
OM951_19795	COG1028	Short-chain dehydrogenase reductase Sdr
OM951_19845	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
OM951_19850	COG1074	ATP-dependent DNA helicase activity
OM951_19855	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
OM951_19890	COG1127	ABC transporter
OM951_19895	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
OM951_19900	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
OM951_19915	COG2853	Lipoprotein
OM951_19930	COG0386	Belongs to the glutathione peroxidase family
OM951_19940	COG1322	Protein conserved in bacteria
OM951_19950	COG0583	DNA-binding transcription factor activity
OM951_19970	COG0531	amino acid
OM951_19975	COG3537	Alpha-1,2-mannosidase
OM951_19995	COG2199	diguanylate cyclase activity
OM951_19995	COG2203	Gaf domain
OM951_20000	COG3835	regulator
OM951_20005	COG1929	Belongs to the glycerate kinase type-1 family
OM951_20025	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
OM951_20030	COG0861	Integral membrane protein TerC family
OM951_20040	COG0584	glycerophosphoryl diester phosphodiesterase
OM951_20055	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
OM951_20060	COG0726	polysaccharide deacetylase
OM951_20070	COG0706	membrane insertase activity
OM951_20075	COG0594	ribonuclease P activity
OM951_20095	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
OM951_20100	COG0187	DNA topoisomerase II activity
OM951_20110	COG0501	Belongs to the peptidase M48B family
OM951_20165	COG1028	Short-chain dehydrogenase reductase Sdr
OM951_20170	COG0300	oxidoreductase activity
OM951_20190	COG1272	protein, Hemolysin III
OM951_20195	COG1111	helicase
OM951_20195	COG1205	dead DEAH box helicase
OM951_20285	COG0070	glutamate synthase
OM951_20285	COG0069	glutamate synthase activity
OM951_20285	COG0067	glutamate synthase
OM951_20290	COG0493	'glutamate synthase
OM951_20305	COG1064	alcohol dehydrogenase
OM951_20310	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
OM951_20320	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
OM951_20325	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
OM951_20335	COG2234	aminopeptidase activity
OM951_20345	COG4942	peptidase
OM951_20350	COG0793	Belongs to the peptidase S41A family
OM951_20395	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OM951_20405	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
OM951_20420	COG3328	transposase activity
OM951_20425	COG2249	NAD(P)H dehydrogenase (quinone) activity
OM951_20435	COG3039	Transposase
OM951_20450	COG3039	Transposase
OM951_20460	COG3237	CsbD-like
OM951_20510	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OM951_20515	COG0477	Major facilitator Superfamily
OM951_20560	COG0714	Associated with various cellular activities
OM951_20610	COG4772	TonB-dependent receptor
OM951_20635	COG1304	FMN binding
OM951_20640	COG1755	Isoprenylcysteine carboxyl methyltransferase
OM951_20645	COG4585	Histidine kinase
OM951_20650	COG2197	response regulator
OM951_20675	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
OM951_20720	COG2801	Transposase and inactivated derivatives
OM951_20730	COG3328	transposase activity
OM951_20740	COG0730	response to heat
OM951_20765	COG3039	Transposase
OM951_20785	COG3328	transposase activity
OM951_20800	COG3039	Transposase
OM951_20815	COG0366	Alpha amylase catalytic
OM951_20820	COG0366	Alpha amylase catalytic
OM951_20825	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
OM951_20845	COG0657	acetylesterase activity
OM951_20845	COG2755	lipolytic protein G-D-S-L family
OM951_20855	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
OM951_20870	COG3507	Belongs to the glycosyl hydrolase 43 family
OM951_20875	COG1609	Transcriptional regulator
OM951_20880	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
OM951_20885	COG1028	Short-chain dehydrogenase reductase Sdr
OM951_20895	COG3039	Transposase
OM951_20905	COG2755	lipolytic protein G-D-S-L family
OM951_20915	COG3186	Phenylalanine-4-hydroxylase
OM951_20920	COG1522	sequence-specific DNA binding
OM951_20930	COG1752	Esterase of the alpha-beta hydrolase superfamily
OM951_20940	COG1119	ATPase activity
OM951_20955	COG1125	glycine betaine transport
OM951_20955	COG0517	IMP dehydrogenase activity
OM951_20970	COG1262	PFAM Formylglycine-generating sulfatase enzyme
OM951_21000	COG0489	protein tyrosine kinase activity
OM951_21005	COG2062	phosphohistidine phosphatase, SixA
OM951_21015	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OM951_21055	COG1968	undecaprenyl-diphosphatase activity
OM951_21060	COG0174	glutamine synthetase
OM951_21065	COG0347	Belongs to the P(II) protein family
OM951_21070	COG0004	ammonium transporteR
OM951_21075	COG3852	Histidine kinase
OM951_21080	COG2204	response regulator
OM951_21085	COG2032	superoxide dismutase activity
OM951_21090	COG2032	superoxide dismutase activity
OM951_21105	COG0183	Belongs to the thiolase family
OM951_21140	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OM951_21145	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
OM951_21150	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
OM951_21175	COG2205	protein histidine kinase activity
OM951_21200	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
OM951_21215	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OM951_21220	COG3177	Filamentation induced by cAMP protein fic
OM951_21225	COG0596	Alpha beta hydrolase
OM951_21230	COG0727	PFAM Uncharacterised protein family (UPF0153)
OM951_21235	COG0318	PFAM AMP-dependent synthetase and ligase
OM951_21240	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OM951_21255	COG1181	Belongs to the D-alanine--D-alanine ligase family
OM951_21265	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
OM951_21275	COG0564	pseudouridine synthase activity
OM951_21295	COG1446	asparaginase
OM951_21300	COG0339	signal peptide processing
OM951_21335	COG0475	glutathione-regulated potassium exporter activity
OM951_21340	COG0583	DNA-binding transcription factor activity
OM951_21345	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
OM951_21350	COG2224	Isocitrate lyase
OM951_21390	COG4770	biotin carboxylase activity
OM951_21395	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
OM951_21400	COG1960	acyl-CoA dehydrogenase activity
OM951_21465	COG0697	spore germination
OM951_21475	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
OM951_21480	COG1846	Transcriptional regulator
OM951_21485	COG1764	response to oxidative stress
OM951_21505	COG2130	NADP-dependent
OM951_21520	COG1187	pseudouridine synthase activity
OM951_21530	COG1643	Atp-dependent helicase
OM951_21535	COG4807	Protein conserved in bacteria
OM951_21545	COG2072	flavoprotein involved in K transport
OM951_21565	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
OM951_21575	COG0583	DNA-binding transcription factor activity
OM951_21610	COG2252	PERMEase
OM951_21630	COG0084	hydrolase, TatD family'
OM951_21645	COG0583	DNA-binding transcription factor activity
OM951_21650	COG2814	Major facilitator Superfamily
OM951_21665	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
OM951_21670	COG1902	pentaerythritol trinitrate reductase activity
OM951_21690	COG0745	RESPONSE REGULATOR receiver
OM951_21695	COG2205	protein histidine kinase activity
OM951_21700	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OM951_21725	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
OM951_21730	COG0583	DNA-binding transcription factor activity
OM951_21765	COG0702	epimerase
OM951_21770	COG1733	regulation of RNA biosynthetic process
OM951_21815	COG0129	dihydroxy-acid dehydratase activity
OM951_21830	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
OM951_21890	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
OM951_21915	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
OM951_21930	COG3485	protocatechuate 3,4-dioxygenase
OM951_21935	COG3485	protocatechuate 3,4-dioxygenase
OM951_21945	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OM951_21950	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OM951_21960	COG1414	Transcriptional regulator
OM951_21970	COG0657	acetylesterase activity
OM951_21980	COG0445	tRNA wobble uridine modification
OM951_21990	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
OM951_22020	COG2267	carboxylic ester hydrolase activity
OM951_22030	COG0156	8-amino-7-oxononanoate synthase activity
OM951_22035	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
OM951_22040	COG1040	competence protein
OM951_22045	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
OM951_22065	COG3039	Transposase
OM951_22130	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
OM951_22200	COG3264	Mechanosensitive ion channel
OM951_22200	COG1511	domain protein
OM951_22205	COG1368	sulfuric ester hydrolase activity
OM951_22210	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
OM951_22215	COG2354	Protein conserved in bacteria
OM951_22225	COG0297	glycogen (starch) synthase activity
OM951_22230	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
OM951_22235	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
OM951_22260	COG0702	epimerase
OM951_22270	COG1858	cytochrome C peroxidase
OM951_22280	COG2801	Transposase and inactivated derivatives
OM951_22290	COG3209	COG3209 Rhs family protein
OM951_22295	COG3039	Transposase
OM951_22305	COG1028	Short-chain dehydrogenase reductase Sdr
OM951_22340	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OM951_22345	COG1028	Short-chain dehydrogenase reductase Sdr
OM951_22355	COG0513	Belongs to the DEAD box helicase family
OM951_22360	COG0508	dehydrogenase complex catalyzes the overall conversion of
OM951_22385	COG3483	tryptophan 2,3-dioxygenase activity
OM951_22390	COG2801	Transposase and inactivated derivatives
OM951_22410	COG3328	transposase activity
OM951_22615	COG4962	Type ii secretion system protein e
OM951_22630	COG3451	type IV secretory pathway VirB4
OM951_22645	COG3846	protein secretion by the type IV secretion system
OM951_22680	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OM951_22695	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OM951_22710	COG1487	ribonuclease activity
OM951_22715	COG4691	Plasmid stability protein
OM951_22720	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
OM951_22780	COG3328	transposase activity
OM951_22800	COG3328	transposase activity
OM951_22845	COG3328	transposase activity
OM951_22905	COG3328	transposase activity
OM951_22985	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
OM951_22990	COG4691	Plasmid stability protein
OM951_22995	COG1487	ribonuclease activity