locus-tag	class	description
DGM81_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DGM81_00025	COG0187	DNA topoisomerase II activity
DGM81_00035	COG0501	Belongs to the peptidase M48B family
DGM81_00090	COG3328	transposase activity
DGM81_00105	COG3318	Belongs to the UPF0149 family
DGM81_00105	COG3012	SEC-C Motif Domain Protein
DGM81_00145	COG3328	transposase activity
DGM81_00250	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DGM81_00255	COG1074	ATP-dependent DNA helicase activity
DGM81_00260	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
DGM81_00295	COG1127	ABC transporter
DGM81_00300	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
DGM81_00305	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
DGM81_00320	COG2853	Lipoprotein
DGM81_00360	COG3328	transposase activity
DGM81_00385	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DGM81_00395	COG4221	oxidoreductase activity
DGM81_00400	COG0583	DNA-binding transcription factor activity
DGM81_00410	COG0477	Major facilitator Superfamily
DGM81_00415	COG1289	transmembrane transporter activity
DGM81_00425	COG1566	PFAM secretion protein HlyD family protein
DGM81_00440	COG0302	gtp cyclohydrolase
DGM81_00460	COG3328	transposase activity
DGM81_00470	COG0730	response to heat
DGM81_00575	COG3012	SEC-C Motif Domain Protein
DGM81_00585	COG0676	glucose-6-phosphate 1-epimerase activity
DGM81_00610	COG3135	benzoate transporter
DGM81_00640	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DGM81_00650	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
DGM81_00660	COG1435	thymidine kinase activity
DGM81_00665	COG0210	DNA helicase
DGM81_00715	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DGM81_00730	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
DGM81_00735	COG0284	orotidine-5'-phosphate decarboxylase activity
DGM81_00770	COG2937	Belongs to the GPAT DAPAT family
DGM81_00810	COG3328	transposase activity
DGM81_00845	COG2211	Major facilitator Superfamily
DGM81_00860	COG3693	PFAM glycoside hydrolase, family 10
DGM81_00870	COG3693	PFAM glycoside hydrolase, family 10
DGM81_00875	COG1904	glucuronate isomerase
DGM81_00880	COG3250	beta-galactosidase activity
DGM81_00890	COG3386	PFAM SMP-30 Gluconolaconase
DGM81_00915	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DGM81_00980	COG0246	Mannitol dehydrogenase
DGM81_00985	COG1472	Belongs to the glycosyl hydrolase 3 family
DGM81_00995	COG4948	Mandelate Racemase Muconate Lactonizing
DGM81_01005	COG3661	Belongs to the glycosyl hydrolase 67 family
DGM81_01015	COG2115	Belongs to the xylose isomerase family
DGM81_01025	COG0037	tRNA processing
DGM81_01030	COG2974	May be involved in recombination
DGM81_01050	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
DGM81_01060	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DGM81_01065	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DGM81_01070	COG0805	protein transport
DGM81_01085	COG0519	Catalyzes the synthesis of GMP from XMP
DGM81_01085	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DGM81_01105	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DGM81_01110	COG0752	glycyl-tRNA synthetase alpha subunit
DGM81_01120	COG0457	Tetratricopeptide repeat
DGM81_01130	COG4771	TonB-dependent receptor
DGM81_01135	COG0729	surface antigen
DGM81_01140	COG2911	Protein conserved in bacteria
DGM81_01160	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DGM81_01170	COG3265	gluconokinase activity
DGM81_01175	COG2211	Major facilitator Superfamily
DGM81_01180	COG3459	Glycosyltransferase 36 associated
DGM81_01195	COG2205	protein histidine kinase activity
DGM81_01200	COG1971	Probably functions as a manganese efflux pump
DGM81_01210	COG1917	Cupin 2, conserved barrel domain protein
DGM81_01210	COG2207	Transcriptional regulator
DGM81_01215	COG1414	Transcriptional regulator
DGM81_01220	COG0738	Major facilitator superfamily
DGM81_01225	COG3254	rhamnose metabolic process
DGM81_01230	COG4948	Mandelate Racemase Muconate Lactonizing
DGM81_01235	COG0179	Fumarylacetoacetate (FAA) hydrolase
DGM81_01240	COG1028	Short-chain dehydrogenase reductase Sdr
DGM81_01260	COG3507	Belongs to the glycosyl hydrolase 43 family
DGM81_01295	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DGM81_01305	COG3162	membrane
DGM81_01310	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DGM81_01320	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DGM81_01330	COG1846	Transcriptional regulator
DGM81_01330	COG1940	carbohydrate kinase activity
DGM81_01335	COG0708	Exodeoxyribonuclease III
DGM81_01350	COG2091	lysine biosynthetic process via aminoadipic acid
DGM81_01360	COG3540	Alkaline phosphatase
DGM81_01365	COG0357	Ribosomal RNA small subunit methyltransferase G
DGM81_01390	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DGM81_01415	COG2159	amidohydrolase
DGM81_01430	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
DGM81_01435	COG0583	DNA-binding transcription factor activity
DGM81_01440	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DGM81_01455	COG0210	DNA helicase
DGM81_01545	COG3328	transposase activity
DGM81_01570	COG0154	amidase activity
DGM81_01645	COG0583	DNA-binding transcription factor activity
DGM81_01650	COG0667	Aldo Keto reductase
DGM81_01675	COG0631	protein serine/threonine phosphatase activity
DGM81_01680	COG0515	serine threonine protein kinase
DGM81_01720	COG0408	coproporphyrinogen oxidase activity
DGM81_01770	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DGM81_01785	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DGM81_01825	COG1028	Short-chain dehydrogenase reductase Sdr
DGM81_01835	COG0463	Glycosyl transferase, family 2
DGM81_01845	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DGM81_01850	COG3100	YcgL domain-containing protein
DGM81_01865	COG3387	PFAM Glycoside hydrolase 15-related
DGM81_01870	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DGM81_01910	COG2239	Acts as a magnesium transporter
DGM81_01915	COG1042	CoA-binding domain protein
DGM81_01915	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DGM81_01915	COG0045	succinate-CoA ligase (ADP-forming) activity
DGM81_01930	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DGM81_01935	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DGM81_01955	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DGM81_01990	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DGM81_01995	COG0842	Transport permease protein
DGM81_02000	COG1131	(ABC) transporter
DGM81_02005	COG0633	Ferredoxin
DGM81_02005	COG0543	2 iron, 2 sulfur cluster binding
DGM81_02010	COG1230	cation diffusion facilitator family transporter
DGM81_02030	COG1476	TRANSCRIPTIONal
DGM81_02040	COG4555	ABC transporter
DGM81_02125	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DGM81_02140	COG1199	ATP-dependent helicase activity
DGM81_02155	COG3328	transposase activity
DGM81_02195	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DGM81_02225	COG3228	Belongs to the MtfA family
DGM81_02240	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
DGM81_02240	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
DGM81_02245	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
DGM81_02260	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DGM81_02305	COG3237	CsbD-like
DGM81_02310	COG0180	Tryptophanyl-tRNA synthetase
DGM81_02315	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DGM81_02340	COG0697	spore germination
DGM81_02365	COG1136	(ABC) transporter
DGM81_02370	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DGM81_02375	COG4585	Histidine kinase
DGM81_02380	COG2197	response regulator
DGM81_02395	COG0753	catalase activity
DGM81_02410	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
DGM81_02415	COG1011	Hydrolase
DGM81_02440	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DGM81_02460	COG0642	Histidine kinase
DGM81_02470	COG1090	epimerase
DGM81_02510	COG1690	Belongs to the RtcB family
DGM81_02545	COG4943	cyclic-guanylate-specific phosphodiesterase activity
DGM81_02560	COG0606	chelatase, subunit chli
DGM81_02580	COG3291	Pkd domain containing protein
DGM81_02580	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DGM81_02600	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
DGM81_02605	COG1166	arginine decarboxylase activity
DGM81_02610	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DGM81_02620	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
DGM81_02620	COG2755	lipolytic protein G-D-S-L family
DGM81_02625	COG4221	oxidoreductase activity
DGM81_02640	COG0018	arginyl-trna synthetase
DGM81_02645	COG2003	Belongs to the UPF0758 family
DGM81_02650	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DGM81_02655	COG0756	dUTP diphosphatase activity
DGM81_02675	COG0463	Glycosyl transferase, family 2
DGM81_02690	COG1475	DNA binding
DGM81_02695	COG1192	Involved in chromosome partitioning
DGM81_02705	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DGM81_02710	COG0708	Exodeoxyribonuclease III
DGM81_02715	COG2211	Major facilitator Superfamily
DGM81_02725	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
DGM81_02735	COG0739	heme binding
DGM81_02740	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DGM81_02780	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
DGM81_02795	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
DGM81_02825	COG0109	protoheme IX farnesyltransferase activity
DGM81_02840	COG0358	DNA primase activity
DGM81_02845	COG1295	ribonuclease BN
DGM81_02855	COG1610	YqeY-like protein
DGM81_02865	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DGM81_02870	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
DGM81_02880	COG2133	pyrroloquinoline quinone binding
DGM81_02885	COG4682	membrane
DGM81_02890	COG3328	transposase activity
DGM81_02910	COG0531	amino acid
DGM81_02930	COG3023	N-Acetylmuramoyl-L-alanine amidase
DGM81_02935	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
DGM81_02975	COG5383	Protein conserved in bacteria
DGM81_02995	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DGM81_03000	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DGM81_03005	COG1473	amidohydrolase
DGM81_03010	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
DGM81_03010	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
DGM81_03015	COG1652	LysM domain
DGM81_03040	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
DGM81_03050	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DGM81_03055	COG3118	belongs to the thioredoxin family
DGM81_03060	COG0513	Belongs to the DEAD box helicase family
DGM81_03065	COG2884	Cell division ATP-binding protein ftsE
DGM81_03070	COG2177	Part of the ABC transporter FtsEX involved in
DGM81_03075	COG3437	response regulator, receiver
DGM81_03080	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DGM81_03085	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DGM81_03090	COG2860	membrane
DGM81_03095	COG1252	NADH dehydrogenase
DGM81_03110	COG0625	glutathione transferase activity
DGM81_03115	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DGM81_03135	COG0534	Mate efflux family protein
DGM81_03140	COG0616	signal peptide processing
DGM81_03150	COG1028	Short-chain dehydrogenase reductase Sdr
DGM81_03165	COG0009	L-threonylcarbamoyladenylate synthase
DGM81_03170	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DGM81_03170	COG1754	DNA topoisomerase type I activity
DGM81_03190	COG0758	DNA mediated transformation
DGM81_03195	COG1652	LysM domain
DGM81_03200	COG0242	peptide deformylase activity
DGM81_03205	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DGM81_03210	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DGM81_03210	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DGM81_03255	COG1560	Kdo2-lipid A biosynthetic process
DGM81_03260	COG1490	D-aminoacyl-tRNA deacylase activity
DGM81_03265	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DGM81_03300	COG0024	Methionine aminopeptidase
DGM81_03310	COG0038	chloride channel
DGM81_03315	COG0659	secondary active sulfate transmembrane transporter activity
DGM81_03340	COG0251	oxidation-reduction process
DGM81_03410	COG3328	transposase activity
DGM81_03425	COG2951	lytic endotransglycosylase activity
DGM81_03430	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
DGM81_03435	COG1686	Belongs to the peptidase S11 family
DGM81_03445	COG2921	Belongs to the UPF0250 family
DGM81_03450	COG0321	lipoyl(octanoyl) transferase activity
DGM81_03455	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
DGM81_03480	COG1056	cytidyltransferase-related domain
DGM81_03480	COG1051	belongs to the nudix hydrolase family
DGM81_03515	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
DGM81_03520	COG0673	inositol 2-dehydrogenase activity
DGM81_03525	COG2823	Periplasmic or secreted lipoprotein
DGM81_03530	COG4251	negative regulation of phosphorylation
DGM81_03535	COG0784	Response regulator, receiver
DGM81_03540	COG4191	Histidine kinase
DGM81_03545	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DGM81_03600	COG1459	type II secretion system
DGM81_03645	COG2188	Transcriptional regulator
DGM81_03655	COG1609	Transcriptional regulator
DGM81_03660	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DGM81_03665	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
DGM81_03675	COG0617	tRNA 3'-terminal CCA addition
DGM81_03695	COG0525	valine-tRNA ligase activity
DGM81_03710	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
DGM81_03720	COG0795	lipopolysaccharide-transporting ATPase activity
DGM81_03735	COG4974	Belongs to the 'phage' integrase family
DGM81_03750	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DGM81_03760	COG0047	phosphoribosylformylglycinamidine synthase activity
DGM81_03760	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DGM81_03765	COG5295	Hep Hag repeat protein
DGM81_03770	COG1404	Belongs to the peptidase S8 family
DGM81_03775	COG5295	Hep Hag repeat protein
DGM81_03780	COG1404	Belongs to the peptidase S8 family
DGM81_03785	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DGM81_03795	COG1459	type II secretion system
DGM81_03800	COG2165	general secretion pathway protein
DGM81_03805	COG4970	Tfp pilus assembly protein FimT
DGM81_03810	COG2165	general secretion pathway protein
DGM81_03815	COG4795	General secretion pathway protein
DGM81_03820	COG3156	type II secretion system protein K
DGM81_03825	COG3166	PFAM Fimbrial assembly family protein
DGM81_03840	COG1450	Type ii and iii secretion system protein
DGM81_03850	COG2188	Transcriptional regulator
DGM81_03885	COG3039	Transposase
DGM81_03935	COG1215	transferase activity, transferring glycosyl groups
DGM81_03940	COG1215	transferase activity, transferring glycosyl groups
DGM81_03945	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
DGM81_03970	COG0242	peptide deformylase activity
DGM81_03975	COG0488	(ABC) transporter
DGM81_03985	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DGM81_03990	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DGM81_04000	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DGM81_04000	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DGM81_04020	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
DGM81_04025	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DGM81_04030	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
DGM81_04050	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
DGM81_04055	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
DGM81_04065	COG2205	protein histidine kinase activity
DGM81_04070	COG0745	RESPONSE REGULATOR receiver
DGM81_04080	COG0277	FAD linked oxidase domain protein
DGM81_04085	COG1988	membrane-bound metal-dependent
DGM81_04090	COG0792	nuclease activity
DGM81_04135	COG3116	cell division
DGM81_04145	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DGM81_04150	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DGM81_04155	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DGM81_04165	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DGM81_04170	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DGM81_04175	COG1181	Belongs to the D-alanine--D-alanine ligase family
DGM81_04180	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
DGM81_04195	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
DGM81_04205	COG0739	heme binding
DGM81_04210	COG0653	protein targeting
DGM81_04215	COG0494	nUDIX hydrolase
DGM81_04225	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
DGM81_04235	COG0604	alcohol dehydrogenase
DGM81_04235	COG1028	Short-chain dehydrogenase reductase Sdr
DGM81_04235	COG3321	synthase
DGM81_04255	COG0366	Alpha amylase catalytic
DGM81_04285	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
DGM81_04290	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
DGM81_04300	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
DGM81_04340	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DGM81_04350	COG4106	trans-aconitate 2-methyltransferase activity
DGM81_04355	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DGM81_04370	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DGM81_04375	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DGM81_04380	COG0667	Aldo Keto reductase
DGM81_04390	COG4771	TonB-dependent receptor
DGM81_04410	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DGM81_04415	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
DGM81_04425	COG2175	clavaminate synthase activity
DGM81_04435	COG4181	ATPase activity
DGM81_04450	COG0642	Histidine kinase
DGM81_04460	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
DGM81_04470	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
DGM81_04480	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DGM81_04485	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
DGM81_04500	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
DGM81_04505	COG2967	ApaG domain
DGM81_04510	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DGM81_04515	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
DGM81_04520	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DGM81_04525	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
DGM81_04540	COG0123	including yeast histone deacetylase and acetoin utilization protein
DGM81_04545	COG2096	Adenosyltransferase
DGM81_04560	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DGM81_04565	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DGM81_04595	COG3384	dioxygenase
DGM81_04600	COG0583	DNA-binding transcription factor activity
DGM81_04605	COG0318	PFAM AMP-dependent synthetase and ligase
DGM81_04615	COG1024	Enoyl-CoA hydratase
DGM81_04635	COG3386	PFAM SMP-30 Gluconolaconase
DGM81_04645	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
DGM81_04665	COG0697	spore germination
DGM81_04675	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DGM81_04700	COG2197	response regulator
DGM81_04710	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DGM81_04725	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DGM81_04730	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DGM81_04740	COG0583	DNA-binding transcription factor activity
DGM81_04745	COG3634	alkyl hydroperoxide reductase activity
DGM81_04755	COG2890	protein-(glutamine-N5) methyltransferase activity
DGM81_04775	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DGM81_04775	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DGM81_04815	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
DGM81_04830	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DGM81_04835	COG1404	Belongs to the peptidase S8 family
DGM81_04840	COG1404	Belongs to the peptidase S8 family
DGM81_04845	COG1404	Belongs to the peptidase S8 family
DGM81_04875	COG1295	ribonuclease BN
DGM81_04880	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DGM81_04885	COG1254	Belongs to the acylphosphatase family
DGM81_04900	COG0521	Mo-molybdopterin cofactor biosynthetic process
DGM81_04910	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DGM81_04915	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
DGM81_04925	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
DGM81_04930	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
DGM81_04940	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DGM81_04945	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
DGM81_04950	COG0193	aminoacyl-tRNA hydrolase activity
DGM81_04955	COG0012	GTP binding
DGM81_04975	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DGM81_04990	COG0250	Participates in transcription elongation, termination and antitermination
DGM81_04995	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DGM81_05000	COG0081	regulation of translation
DGM81_05005	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DGM81_05015	COG0085	RNA polymerase activity
DGM81_05020	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DGM81_05025	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DGM81_05030	COG0049	tRNA binding
DGM81_05035	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DGM81_05040	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DGM81_05055	COG3328	transposase activity
DGM81_05060	COG0051	transcription antitermination factor activity, RNA binding
DGM81_05065	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DGM81_05070	COG0088	Forms part of the polypeptide exit tunnel
DGM81_05075	COG0089	rRNA binding
DGM81_05080	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DGM81_05085	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DGM81_05095	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DGM81_05100	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DGM81_05105	COG0255	Belongs to the universal ribosomal protein uL29 family
DGM81_05110	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DGM81_05120	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DGM81_05125	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DGM81_05135	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DGM81_05140	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DGM81_05145	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DGM81_05155	COG1841	ribosomal large subunit assembly
DGM81_05160	COG0200	Binds to the 23S rRNA
DGM81_05165	COG0201	protein transport
DGM81_05190	COG0203	ribosomal protein L17
DGM81_05195	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
DGM81_05215	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
DGM81_05225	COG0154	amidase activity
DGM81_05235	COG1217	gtp-binding protein TYPA
DGM81_05240	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DGM81_05245	COG0039	L-malate dehydrogenase activity
DGM81_05250	COG0625	glutathione transferase activity
DGM81_05270	COG1902	pentaerythritol trinitrate reductase activity
DGM81_05270	COG0446	pyridine nucleotide-disulphide oxidoreductase
DGM81_05275	COG0604	alcohol dehydrogenase
DGM81_05285	COG3039	Transposase
DGM81_05290	COG2885	chlorophyll binding
DGM81_05310	COG0156	8-amino-7-oxononanoate synthase activity
DGM81_05315	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
DGM81_05320	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
DGM81_05325	COG4208	sulfate ABC transporter
DGM81_05330	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
DGM81_05360	COG0406	alpha-ribazole phosphatase activity
DGM81_05370	COG0285	dihydrofolate synthase activity
DGM81_05390	COG2833	Protein of unknown function (DUF455)
DGM81_05410	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DGM81_05415	COG0671	phosphoesterase, PA-phosphatase related
DGM81_05420	COG0438	transferase activity, transferring glycosyl groups
DGM81_05430	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
DGM81_05445	COG4783	chaperone-mediated protein folding
DGM81_05460	COG0473	3-isopropylmalate dehydrogenase activity
DGM81_05500	COG3328	transposase activity
DGM81_05515	COG0544	peptidyl-prolyl cis-trans isomerase activity
DGM81_05525	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DGM81_05555	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DGM81_05565	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DGM81_05575	COG0328	RNA-DNA hybrid ribonuclease activity
DGM81_05580	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DGM81_05585	COG0631	protein serine/threonine phosphatase activity
DGM81_05610	COG0859	PFAM glycosyl transferase family 9
DGM81_05615	COG3642	lipopolysaccharide core region biosynthetic process
DGM81_05620	COG1234	tRNA 3'-trailer cleavage
DGM81_05625	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DGM81_05635	COG0315	cyclic pyranopterin monophosphate synthase activity
DGM81_05640	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
DGM81_05645	COG0314	molybdopterin synthase activity
DGM81_05665	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DGM81_05670	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DGM81_05675	COG0537	adenosine 5'-monophosphoramidase activity
DGM81_05695	COG0714	Associated with various cellular activities
DGM81_05710	COG0424	maF-like protein
DGM81_05715	COG1399	metal-binding, possibly nucleic acid-binding protein
DGM81_05720	COG0333	Belongs to the bacterial ribosomal protein bL32 family
DGM81_05725	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DGM81_05740	COG1028	Short-chain dehydrogenase reductase Sdr
DGM81_05755	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DGM81_05760	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DGM81_05795	COG3829	transcription factor binding
DGM81_05845	COG2373	Large extracellular alpha-helical protein
DGM81_05870	COG3852	Histidine kinase
DGM81_05875	COG4953	penicillin-binding protein 1C
DGM81_05885	COG0678	peroxiredoxin activity
DGM81_05905	COG0330	HflC and HflK could
DGM81_05910	COG0330	HflC and HflK could
DGM81_05920	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DGM81_05925	COG0308	aminopeptidase N
DGM81_05935	COG1028	Short-chain dehydrogenase reductase Sdr
DGM81_05940	COG1309	transcriptional regulator
DGM81_06000	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
DGM81_06010	COG3387	PFAM Glycoside hydrolase 15-related
DGM81_06015	COG1028	Short-chain dehydrogenase reductase Sdr
DGM81_06025	COG3537	Alpha-1,2-mannosidase
DGM81_06050	COG0492	ferredoxin-NADP+ reductase activity
DGM81_06080	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DGM81_06085	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
DGM81_06090	COG2080	2 iron, 2 sulfur cluster binding
DGM81_06125	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DGM81_06140	COG0587	DNA-directed DNA polymerase activity
DGM81_06160	COG1297	OPT oligopeptide transporter protein
DGM81_06195	COG1506	peptidase
DGM81_06195	COG0823	Involved in the tonB-independent uptake of proteins
DGM81_06235	COG2207	Transcriptional regulator
DGM81_06235	COG1917	Cupin 2, conserved barrel domain protein
DGM81_06250	COG3328	transposase activity
DGM81_06265	COG0753	catalase activity
DGM81_06270	COG0656	L-ascorbic acid biosynthetic process
DGM81_06280	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DGM81_06280	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DGM81_06330	COG2963	transposase activity
DGM81_06340	COG2194	sulfuric ester hydrolase activity
DGM81_06355	COG0745	RESPONSE REGULATOR receiver
DGM81_06360	COG0642	Histidine kinase
DGM81_06370	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
DGM81_06375	COG2894	cell division
DGM81_06380	COG0850	regulation of cytokinetic process
DGM81_06395	COG4585	Histidine kinase
DGM81_06400	COG2197	response regulator
DGM81_06415	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
DGM81_06445	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
DGM81_06455	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
DGM81_06470	COG1595	DNA-templated transcription, initiation
DGM81_06480	COG1946	Acyl-CoA thioesterase
DGM81_06495	COG0824	Thioesterase
DGM81_06500	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DGM81_06505	COG0261	This protein binds to 23S rRNA in the presence of protein L20
DGM81_06510	COG0211	Belongs to the bacterial ribosomal protein bL27 family
DGM81_06515	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DGM81_06520	COG0268	Binds directly to 16S ribosomal RNA
DGM81_06530	COG0196	riboflavin kinase activity
DGM81_06535	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DGM81_06540	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DGM81_06545	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
DGM81_06560	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DGM81_06565	COG1845	cytochrome c oxidase, subunit III
DGM81_06570	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
DGM81_06585	COG3152	Membrane
DGM81_06595	COG2207	Transcriptional regulator
DGM81_06600	COG0326	Molecular chaperone. Has ATPase activity
DGM81_06610	COG1366	Belongs to the anti-sigma-factor antagonist family
DGM81_06615	COG1366	Belongs to the anti-sigma-factor antagonist family
DGM81_06645	COG4771	TonB-dependent receptor
DGM81_06655	COG5507	3-demethylubiquinone-9 3-methyltransferase
DGM81_06660	COG2205	protein histidine kinase activity
DGM81_06670	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
DGM81_06675	COG3850	Histidine kinase
DGM81_06675	COG3437	response regulator, receiver
DGM81_06675	COG4999	Histidine kinase
DGM81_06675	COG2205	protein histidine kinase activity
DGM81_06680	COG4191	Histidine kinase
DGM81_06680	COG0784	Response regulator, receiver
DGM81_06705	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DGM81_06715	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DGM81_06720	COG0228	four-way junction DNA binding
DGM81_06725	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DGM81_06730	COG0336	Belongs to the RNA methyltransferase TrmD family
DGM81_06735	COG0335	large ribosomal subunit rRNA binding
DGM81_06740	COG0534	Mate efflux family protein
DGM81_06765	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
DGM81_06780	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
DGM81_06820	COG3250	beta-galactosidase activity
DGM81_06825	COG3867	Arabinogalactan endo-beta-1,4-galactanase
DGM81_06845	COG1960	acyl-CoA dehydrogenase activity
DGM81_06875	COG0457	Tetratricopeptide repeat
DGM81_06885	COG0457	Tetratricopeptide repeat
DGM81_06895	COG1024	Enoyl-CoA hydratase
DGM81_06895	COG1250	3-hydroxyacyl-CoA dehydrogenase
DGM81_06910	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DGM81_06920	COG0481	GTPase activity
DGM81_06935	COG0571	ribonuclease III activity
DGM81_06940	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DGM81_06945	COG1381	Involved in DNA repair and RecF pathway recombination
DGM81_06955	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DGM81_06960	COG2954	triphosphatase activity
DGM81_06965	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
DGM81_06970	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
DGM81_06975	COG3046	protein related to deoxyribodipyrimidine photolyase
DGM81_06980	COG1472	Belongs to the glycosyl hydrolase 3 family
DGM81_06985	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
DGM81_06990	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
DGM81_06995	COG1278	Cold shock
DGM81_07000	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DGM81_07010	COG1201	RNA secondary structure unwinding
DGM81_07015	COG1793	dna ligase
DGM81_07025	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
DGM81_07025	COG1793	dna ligase
DGM81_07065	COG0183	Belongs to the thiolase family
DGM81_07085	COG1451	nucleotide metabolic process
DGM81_07090	COG5487	UPF0391 membrane protein
DGM81_07100	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
DGM81_07120	COG1077	Cell shape determining protein MreB Mrl
DGM81_07125	COG1047	Peptidyl-prolyl cis-trans
DGM81_07135	COG2824	Alkylphosphonate utilization operon protein PhnA
DGM81_07145	COG1902	pentaerythritol trinitrate reductase activity
DGM81_07150	COG2814	Major facilitator Superfamily
DGM81_07185	COG0392	lysyltransferase activity
DGM81_07185	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
DGM81_07195	COG0251	oxidation-reduction process
DGM81_07200	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DGM81_07215	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DGM81_07240	COG1595	DNA-templated transcription, initiation
DGM81_07255	COG2878	Part of a membrane complex involved in electron transport
DGM81_07270	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DGM81_07270	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DGM81_07290	COG0346	lactoylglutathione lyase activity
DGM81_07305	COG0833	amino acid
DGM81_07310	COG2040	homocysteine
DGM81_07320	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
DGM81_07340	COG1695	Transcriptional regulator
DGM81_07360	COG1981	membrane
DGM81_07375	COG0825	malonyl-CoA metabolic process
DGM81_07390	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DGM81_07395	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DGM81_07400	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DGM81_07405	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DGM81_07420	COG0750	zinc metalloprotease
DGM81_07425	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
DGM81_07430	COG0575	Belongs to the CDS family
DGM81_07435	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DGM81_07440	COG0233	cytoplasmic translational termination
DGM81_07445	COG0528	UMP kinase activity
DGM81_07455	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DGM81_07460	COG0052	Belongs to the universal ribosomal protein uS2 family
DGM81_07500	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
DGM81_07510	COG1393	Belongs to the ArsC family
DGM81_07515	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DGM81_07520	COG0367	asparagine synthase
DGM81_07530	COG4774	siderophore transport
DGM81_07590	COG3328	transposase activity
DGM81_07625	COG1566	PFAM secretion protein HlyD family protein
DGM81_07630	COG2814	Major facilitator Superfamily
DGM81_07660	COG3104	oligopeptide transport
DGM81_07690	COG0339	signal peptide processing
DGM81_07695	COG0386	Belongs to the glutathione peroxidase family
DGM81_07755	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
DGM81_07760	COG0084	hydrolase, TatD family'
DGM81_07775	COG1960	acyl-CoA dehydrogenase activity
DGM81_07795	COG0367	asparagine synthase
DGM81_07805	COG0305	Participates in initiation and elongation during chromosome replication
DGM81_07810	COG0415	Belongs to the DNA photolyase family
DGM81_07825	COG0583	DNA-binding transcription factor activity
DGM81_07870	COG3706	GGDEF domain
DGM81_07890	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
DGM81_07905	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DGM81_07915	COG0497	DNA recombination
DGM81_07920	COG1420	regulation of RNA biosynthetic process
DGM81_07925	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DGM81_07930	COG0443	Heat shock 70 kDa protein
DGM81_07935	COG0484	heat shock protein binding
DGM81_07940	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
DGM81_07970	COG0583	DNA-binding transcription factor activity
DGM81_07980	COG1132	(ABC) transporter
DGM81_08015	COG2850	peptidyl-arginine hydroxylation
DGM81_08035	COG1253	flavin adenine dinucleotide binding
DGM81_08070	COG1131	(ABC) transporter
DGM81_08075	COG1725	Transcriptional regulator
DGM81_08085	COG0386	Belongs to the glutathione peroxidase family
DGM81_08105	COG2900	Belongs to the SlyX family
DGM81_08135	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DGM81_08145	COG1410	methionine synthase
DGM81_08145	COG0646	methionine synthase
DGM81_08150	COG0646	methionine synthase
DGM81_08150	COG1410	methionine synthase
DGM81_08155	COG2226	methyltransferase
DGM81_08160	COG1960	acyl-CoA dehydrogenase activity
DGM81_08165	COG1960	acyl-CoA dehydrogenase activity
DGM81_08180	COG0557	exoribonuclease II activity
DGM81_08190	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DGM81_08205	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DGM81_08215	COG0704	Plays a role in the regulation of phosphate uptake
DGM81_08220	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DGM81_08225	COG0581	inorganic phosphate transmembrane transporter activity
DGM81_08230	COG0573	inorganic phosphate transmembrane transporter activity
DGM81_08235	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DGM81_08260	COG0659	secondary active sulfate transmembrane transporter activity
DGM81_08265	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DGM81_08275	COG1024	Enoyl-CoA hydratase
DGM81_08285	COG0494	nUDIX hydrolase
DGM81_08320	COG0488	(ABC) transporter
DGM81_08330	COG0116	Belongs to the methyltransferase superfamily
DGM81_08330	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
DGM81_08335	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DGM81_08355	COG2925	Exonuclease
DGM81_08365	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DGM81_08370	COG3844	kynureninase activity
DGM81_08380	COG0662	Cupin 2, conserved barrel domain protein
DGM81_08385	COG0288	reversible hydration of carbon dioxide
DGM81_08465	COG0017	Asparaginyl-tRNA synthetase
DGM81_08475	COG0316	Belongs to the HesB IscA family
DGM81_08480	COG0360	Binds together with S18 to 16S ribosomal RNA
DGM81_08485	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DGM81_08490	COG0359	binds to the 23S rRNA
DGM81_08500	COG3115	cell septum assembly
DGM81_08510	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DGM81_08515	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DGM81_08520	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
DGM81_08535	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
DGM81_08545	COG4993	Dehydrogenase
DGM81_08555	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
DGM81_08570	COG2986	histidine ammonia-lyase
DGM81_08575	COG1228	amidohydrolase
DGM81_08615	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
DGM81_08620	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
DGM81_08625	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
DGM81_08630	COG1605	Chorismate mutase
DGM81_08630	COG0077	Prephenate dehydratase
DGM81_08635	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DGM81_08650	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DGM81_08655	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
DGM81_08660	COG0583	DNA-binding transcription factor activity
DGM81_08685	COG3328	transposase activity
DGM81_08700	COG0840	transmembrane signaling receptor activity
DGM81_08720	COG0784	Response regulator, receiver
DGM81_08720	COG4191	Histidine kinase
DGM81_08730	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
DGM81_08750	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DGM81_08760	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
DGM81_08770	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DGM81_08785	COG1595	DNA-templated transcription, initiation
DGM81_08840	COG2244	polysaccharide biosynthetic process
DGM81_08870	COG2264	protein methyltransferase activity
DGM81_08880	COG0438	transferase activity, transferring glycosyl groups
DGM81_08895	COG1136	(ABC) transporter
DGM81_08905	COG0477	Major facilitator Superfamily
DGM81_08910	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DGM81_08925	COG1253	flavin adenine dinucleotide binding
DGM81_08940	COG0306	phosphate transporter
DGM81_08965	COG0504	CTP synthase activity
DGM81_08970	COG2877	3-deoxy-8-phosphooctulonate synthase activity
DGM81_08980	COG0148	phosphopyruvate hydratase activity
DGM81_08985	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
DGM81_08995	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
DGM81_09000	COG0585	pseudouridine synthase activity
DGM81_09005	COG2840	Smr protein MutS2
DGM81_09010	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
DGM81_09015	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DGM81_09020	COG1238	metal cluster binding
DGM81_09030	COG3737	Protein of unknown function (DUF498/DUF598)
DGM81_09035	COG1534	Rna-binding protein
DGM81_09040	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
DGM81_09050	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DGM81_09055	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DGM81_09065	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DGM81_09070	COG1546	Belongs to the CinA family
DGM81_09080	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DGM81_09085	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DGM81_09095	COG2137	regulation of response to DNA damage stimulus
DGM81_09100	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DGM81_09105	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
DGM81_09125	COG0583	DNA-binding transcription factor activity
DGM81_09150	COG0351	phosphomethylpyrimidine kinase
DGM81_09165	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
DGM81_09170	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DGM81_09185	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DGM81_09195	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
DGM81_09200	COG3734	2-keto-3-deoxy-galactonokinase
DGM81_09210	COG4948	Mandelate Racemase Muconate Lactonizing
DGM81_09215	COG0800	Aldolase
DGM81_09255	COG1501	Belongs to the glycosyl hydrolase 31 family
DGM81_09265	COG1070	Carbohydrate kinase
DGM81_09270	COG2115	Belongs to the xylose isomerase family
DGM81_09275	COG0477	Major facilitator Superfamily
DGM81_09305	COG0860	N-Acetylmuramoyl-L-alanine amidase
DGM81_09315	COG3039	Transposase
DGM81_09345	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
DGM81_09350	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
DGM81_09355	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
DGM81_09360	COG0166	Belongs to the GPI family
DGM81_09380	COG1472	Belongs to the glycosyl hydrolase 3 family
DGM81_09395	COG4251	negative regulation of phosphorylation
DGM81_09395	COG2203	Gaf domain
DGM81_09395	COG3706	GGDEF domain
DGM81_09395	COG5001	Diguanylate cyclase
DGM81_09400	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
DGM81_09405	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
DGM81_09420	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
DGM81_09425	COG0671	phosphoesterase, PA-phosphatase related
DGM81_09435	COG1794	racemase activity, acting on amino acids and derivatives
DGM81_09445	COG0697	spore germination
DGM81_09450	COG0812	UDP-N-acetylmuramate dehydrogenase activity
DGM81_09455	COG0167	dihydroorotate dehydrogenase activity
DGM81_09475	COG1012	belongs to the aldehyde dehydrogenase family
DGM81_09490	COG3328	transposase activity
DGM81_09500	COG0366	Alpha amylase catalytic
DGM81_09520	COG1082	Xylose isomerase domain protein TIM barrel
DGM81_09530	COG2211	Major facilitator Superfamily
DGM81_09545	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DGM81_09550	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DGM81_09565	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
DGM81_09570	COG0072	phenylalanine-tRNA ligase activity
DGM81_09570	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DGM81_09620	COG0438	transferase activity, transferring glycosyl groups
DGM81_09625	COG0438	transferase activity, transferring glycosyl groups
DGM81_09635	COG0438	transferase activity, transferring glycosyl groups
DGM81_09660	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DGM81_09670	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DGM81_09690	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DGM81_09700	COG1960	acyl-CoA dehydrogenase activity
DGM81_09710	COG3040	lipid binding
DGM81_09725	COG0322	excinuclease ABC activity
DGM81_09740	COG0784	Response regulator, receiver
DGM81_09740	COG4191	Histidine kinase
DGM81_09760	COG1194	a g-specific adenine glycosylase
DGM81_09770	COG0552	protein localization to endoplasmic reticulum
DGM81_09780	COG3938	Belongs to the proline racemase family
DGM81_09785	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DGM81_09800	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DGM81_09810	COG0006	proline dipeptidase activity
DGM81_09830	COG0531	amino acid
DGM81_09950	COG3328	transposase activity
DGM81_10015	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
DGM81_10020	COG3328	transposase activity
DGM81_10025	COG0460	homoserine dehydrogenase
DGM81_10025	COG0527	aspartate kinase activity
DGM81_10060	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DGM81_10065	COG0124	histidyl-tRNA synthetase
DGM81_10075	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
DGM81_10080	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DGM81_10085	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DGM81_10090	COG0131	Imidazoleglycerol-phosphate dehydratase
DGM81_10090	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
DGM81_10095	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DGM81_10100	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
DGM81_10105	COG0107	imidazoleglycerol-phosphate synthase activity
DGM81_10110	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DGM81_10110	COG0140	phosphoribosyl-ATP diphosphatase activity
DGM81_10125	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
DGM81_10130	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
DGM81_10135	COG0235	Class ii aldolase
DGM81_10140	COG0531	amino acid
DGM81_10145	COG0531	amino acid
DGM81_10155	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DGM81_10160	COG0277	FAD linked oxidase domain protein
DGM81_10180	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DGM81_10225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DGM81_10230	COG2258	MOSC domain
DGM81_10235	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
DGM81_10240	COG0505	Belongs to the CarA family
DGM81_10250	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DGM81_10255	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DGM81_10265	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DGM81_10285	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
DGM81_10295	COG2198	Histidine kinase
DGM81_10295	COG2205	protein histidine kinase activity
DGM81_10295	COG0784	Response regulator, receiver
DGM81_10300	COG0784	Response regulator, receiver
DGM81_10300	COG2198	Histidine kinase
DGM81_10300	COG2205	protein histidine kinase activity
DGM81_10305	COG1024	Enoyl-CoA hydratase
DGM81_10310	COG0318	PFAM AMP-dependent synthetase and ligase
DGM81_10345	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DGM81_10355	COG2201	protein-glutamate methylesterase activity
DGM81_10360	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
DGM81_10370	COG0840	transmembrane signaling receptor activity
DGM81_10380	COG0835	chemotaxis
DGM81_10395	COG0840	transmembrane signaling receptor activity
DGM81_10400	COG0840	transmembrane signaling receptor activity
DGM81_10405	COG0840	transmembrane signaling receptor activity
DGM81_10410	COG0840	transmembrane signaling receptor activity
DGM81_10415	COG0840	transmembrane signaling receptor activity
DGM81_10430	COG0840	transmembrane signaling receptor activity
DGM81_10435	COG0840	transmembrane signaling receptor activity
DGM81_10440	COG0840	transmembrane signaling receptor activity
DGM81_10445	COG0840	transmembrane signaling receptor activity
DGM81_10460	COG0840	transmembrane signaling receptor activity
DGM81_10475	COG0840	transmembrane signaling receptor activity
DGM81_10480	COG0840	transmembrane signaling receptor activity
DGM81_10490	COG0745	RESPONSE REGULATOR receiver
DGM81_10500	COG0835	chemotaxis
DGM81_10505	COG1192	Involved in chromosome partitioning
DGM81_10510	COG1360	Flagellar Motor Protein
DGM81_10515	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
DGM81_10540	COG3039	Transposase
DGM81_10545	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DGM81_10555	COG1705	Flagellar rod assembly protein muramidase FlgJ
DGM81_10555	COG3951	Flagellar rod assembly protein muramidase FlgJ
DGM81_10560	COG1706	bacterial-type flagellum-dependent cell motility
DGM81_10565	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
DGM81_10575	COG4787	bacterial-type flagellum-dependent cell motility
DGM81_10585	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
DGM81_10590	COG1558	bacterial-type flagellum-dependent cell motility
DGM81_10600	COG0784	Response regulator, receiver
DGM81_10600	COG0835	chemotaxis
DGM81_10620	COG5002	protein histidine kinase activity
DGM81_10630	COG4585	Histidine kinase
DGM81_10650	COG2915	High frequency lysogenization protein hflD homolog
DGM81_10655	COG0482	sulfurtransferase activity
DGM81_10670	COG0542	response to heat
DGM81_10680	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
DGM81_10690	COG0492	ferredoxin-NADP+ reductase activity
DGM81_10695	COG1674	ftsk spoiiie
DGM81_10705	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
DGM81_10720	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DGM81_10725	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DGM81_10730	COG0183	Belongs to the thiolase family
DGM81_10735	COG1024	Enoyl-CoA hydratase
DGM81_10735	COG1250	3-hydroxyacyl-CoA dehydrogenase
DGM81_10770	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DGM81_10775	COG1160	GTP binding
DGM81_10780	COG0303	'Molybdopterin
DGM81_10785	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DGM81_10825	COG0708	Exodeoxyribonuclease III
DGM81_10835	COG0303	'Molybdopterin
DGM81_10840	COG0746	molybdenum cofactor guanylyltransferase activity
DGM81_10865	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DGM81_10865	COG1648	precorrin-2 dehydrogenase activity
DGM81_10875	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DGM81_10885	COG2223	nitrite transmembrane transporter activity
DGM81_10890	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DGM81_10900	COG0243	molybdopterin cofactor binding
DGM81_10915	COG3685	Protein conserved in bacteria
DGM81_10935	COG5001	Diguanylate cyclase
DGM81_10945	COG4566	intracellular signal transduction
DGM81_11000	COG3328	transposase activity
DGM81_11010	COG3039	Transposase
DGM81_11015	COG3328	transposase activity
DGM81_11090	COG3328	transposase activity
DGM81_11100	COG1073	alpha beta
DGM81_11100	COG2226	methyltransferase
DGM81_11115	COG0363	glucosamine-6-phosphate deaminase activity
DGM81_11125	COG3328	transposase activity
DGM81_11150	COG1309	transcriptional regulator
DGM81_11165	COG2154	pterin-4-alpha-carbinolamine dehydratase
DGM81_11175	COG0428	transporter
DGM81_11180	COG3064	Membrane
DGM81_11190	COG1530	ribonuclease E activity
DGM81_11195	COG3039	Transposase
DGM81_11205	COG1054	Belongs to the UPF0176 family
DGM81_11225	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
DGM81_11250	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DGM81_11255	COG0322	excinuclease ABC activity
DGM81_11265	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DGM81_11270	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
DGM81_11275	COG1663	tetraacyldisaccharide 4'-kinase activity
DGM81_11280	COG1132	(ABC) transporter
DGM81_11290	COG0811	peptide transport
DGM81_11305	COG1136	(ABC) transporter
DGM81_11310	COG4591	ABC-type transport system involved in lipoprotein release permease component
DGM81_11320	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
DGM81_11325	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DGM81_11340	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
DGM81_11355	COG0354	folic acid binding
DGM81_11365	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DGM81_11370	COG0837	glucose binding
DGM81_11375	COG0363	glucosamine-6-phosphate deaminase activity
DGM81_11380	COG0129	dihydroxy-acid dehydratase activity
DGM81_11385	COG0800	Aldolase
DGM81_11460	COG0784	Response regulator, receiver
DGM81_11460	COG2205	protein histidine kinase activity
DGM81_11465	COG2183	response to ionizing radiation
DGM81_11475	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DGM81_11475	COG0723	plastoquinol--plastocyanin reductase activity
DGM81_11490	COG3243	poly(R)-hydroxyalkanoic acid synthase
DGM81_11500	COG1183	phosphatidylcholine synthase activity
DGM81_11505	COG1028	Short-chain dehydrogenase reductase Sdr
DGM81_11520	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
DGM81_11535	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
DGM81_11550	COG1914	H( )-stimulated, divalent metal cation uptake system
DGM81_11570	COG2814	Major facilitator Superfamily
DGM81_11585	COG1335	isochorismatase
DGM81_11605	COG2197	response regulator
DGM81_11635	COG0583	DNA-binding transcription factor activity
DGM81_11640	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DGM81_11645	COG3002	Belongs to the UPF0753 family
DGM81_11655	COG0604	alcohol dehydrogenase
DGM81_11690	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DGM81_11690	COG0519	Catalyzes the synthesis of GMP from XMP
DGM81_11700	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DGM81_11715	COG0475	glutathione-regulated potassium exporter activity
DGM81_11715	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DGM81_11720	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DGM81_11730	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DGM81_11735	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
DGM81_11745	COG0776	regulation of translation
DGM81_11750	COG0539	negative regulation of cytoplasmic translation
DGM81_11755	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
DGM81_11770	COG2957	Belongs to the agmatine deiminase family
DGM81_11775	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DGM81_11800	COG0395	ABC-type sugar transport system, permease component
DGM81_11805	COG1175	transmembrane transport
DGM81_11840	COG2350	Protein conserved in bacteria
DGM81_11845	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DGM81_11850	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DGM81_11855	COG1187	pseudouridine synthase activity
DGM81_11870	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DGM81_11875	COG0436	Aminotransferase
DGM81_11880	COG4133	protoheme IX ABC transporter activity
DGM81_11900	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
DGM81_11930	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DGM81_11940	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
DGM81_11945	COG4988	ABC transporter
DGM81_11955	COG1294	oxidase, subunit
DGM81_11985	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DGM81_11990	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DGM81_12000	COG0165	Argininosuccinate lyase
DGM81_12005	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DGM81_12015	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DGM81_12020	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DGM81_12030	COG0137	argininosuccinate synthase activity
DGM81_12035	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DGM81_12045	COG0215	cysteine-tRNA ligase activity
DGM81_12050	COG2166	iron-sulfur cluster assembly
DGM81_12065	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
DGM81_12070	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DGM81_12100	COG4302	ethanolamine ammonia-lyase activity
DGM81_12130	COG3039	Transposase
DGM81_12165	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DGM81_12170	COG0402	S-adenosylhomocysteine deaminase activity
DGM81_12180	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DGM81_12185	COG1509	lysine 2,3-aminomutase activity
DGM81_12190	COG3300	MHYT domain
DGM81_12190	COG5001	Diguanylate cyclase
DGM81_12205	COG0483	inositol monophosphate 1-phosphatase activity
DGM81_12210	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DGM81_12225	COG0488	(ABC) transporter
DGM81_12230	COG0513	Belongs to the DEAD box helicase family
DGM81_12235	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DGM81_12240	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
DGM81_12265	COG0625	glutathione transferase activity
DGM81_12280	COG4681	YaeQ
DGM81_12285	COG2081	HI0933 family
DGM81_12295	COG0501	Belongs to the peptidase M48B family
DGM81_12300	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DGM81_12305	COG1028	Short-chain dehydrogenase reductase Sdr
DGM81_12330	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DGM81_12335	COG0860	N-Acetylmuramoyl-L-alanine amidase
DGM81_12340	COG0802	atpase or kinase
DGM81_12345	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
DGM81_12345	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
DGM81_12350	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DGM81_12355	COG1570	exodeoxyribonuclease VII activity
DGM81_12370	COG1262	PFAM Formylglycine-generating sulfatase enzyme
DGM81_12415	COG0835	chemotaxis
DGM81_12420	COG0840	transmembrane signaling receptor activity
DGM81_12425	COG2094	Belongs to the DNA glycosylase MPG family
DGM81_12430	COG1201	RNA secondary structure unwinding
DGM81_12450	COG2969	positive regulation of protein catabolic process
DGM81_12455	COG0625	glutathione transferase activity
DGM81_12460	COG2857	Cytochrome c1
DGM81_12465	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
DGM81_12470	COG0723	plastoquinol--plastocyanin reductase activity
DGM81_12480	COG0741	lytic transglycosylase activity
DGM81_12495	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DGM81_12500	COG1702	phosphate starvation-inducible protein PhoH
DGM81_12510	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DGM81_12520	COG4535	Mg2 and Co2 transporter CorC
DGM81_12535	COG1012	belongs to the aldehyde dehydrogenase family
DGM81_12540	COG1177	transmembrane transport
DGM81_12545	COG1176	ABC-type spermidine putrescine transport system, permease component I
DGM81_12550	COG3842	ATPase activity
DGM81_12570	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
DGM81_12585	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DGM81_12590	COG0174	glutamine synthetase
DGM81_12595	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DGM81_12605	COG2703	oxygen carrier activity
DGM81_12610	COG0477	Major facilitator Superfamily
DGM81_12620	COG0243	molybdopterin cofactor binding
DGM81_12625	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
DGM81_12630	COG2223	nitrite transmembrane transporter activity
DGM81_12645	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DGM81_12655	COG2733	membrane
DGM81_12660	COG2205	protein histidine kinase activity
DGM81_12660	COG0784	Response regulator, receiver
DGM81_12660	COG5002	protein histidine kinase activity
DGM81_12670	COG0477	Major facilitator Superfamily
DGM81_12675	COG0840	transmembrane signaling receptor activity
DGM81_12710	COG2902	Dehydrogenase
DGM81_12720	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DGM81_12725	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DGM81_12730	COG1609	Transcriptional regulator
DGM81_12735	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DGM81_12735	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
DGM81_12740	COG1105	Belongs to the carbohydrate kinase PfkB family
DGM81_12745	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DGM81_12745	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DGM81_12770	COG3328	transposase activity
DGM81_12780	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DGM81_12790	COG1862	Preprotein translocase
DGM81_12795	COG0343	queuine tRNA-ribosyltransferase activity
DGM81_12800	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
DGM81_12840	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DGM81_12845	COG3291	Pkd domain containing protein
DGM81_12850	COG0405	Gamma-glutamyltransferase
DGM81_12855	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
DGM81_12870	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DGM81_12875	COG0742	ribosomal rna small subunit methyltransferase
DGM81_12880	COG0326	Molecular chaperone. Has ATPase activity
DGM81_12895	COG3328	transposase activity
DGM81_12980	COG3702	type iv secretory pathway
DGM81_13000	COG2948	multi-organism process
DGM81_13020	COG3505	Type IV secretory pathway VirD4
DGM81_13035	COG0556	nucleotide-excision repair
DGM81_13200	COG3179	chitinase
DGM81_13245	COG4695	Portal protein
DGM81_13320	COG3275	phosphorelay sensor kinase activity
DGM81_13325	COG1611	Belongs to the LOG family
DGM81_13340	COG2095	MarC family integral membrane protein
DGM81_13350	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
DGM81_13400	COG1185	polyribonucleotide nucleotidyltransferase activity
DGM81_13405	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DGM81_13410	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DGM81_13415	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DGM81_13420	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DGM81_13425	COG0195	Participates in both transcription termination and antitermination
DGM81_13430	COG0779	Required for maturation of 30S ribosomal subunits
DGM81_13440	COG1007	ATP synthesis coupled electron transport
DGM81_13465	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DGM81_13470	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
DGM81_13480	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
DGM81_13485	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
DGM81_13490	COG0649	NAD binding
DGM81_13495	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DGM81_13500	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DGM81_13505	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DGM81_13520	COG0149	triose-phosphate isomerase activity
DGM81_13525	COG4221	oxidoreductase activity
DGM81_13555	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DGM81_13560	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
DGM81_13565	COG0159	tryptophan synthase activity
DGM81_13575	COG0133	tryptophan synthase activity
DGM81_13585	COG0135	phosphoribosylanthranilate isomerase activity
DGM81_13590	COG0101	tRNA pseudouridine synthase activity
DGM81_13605	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DGM81_13610	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DGM81_13615	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
DGM81_13620	COG2890	protein-(glutamine-N5) methyltransferase activity
DGM81_13630	COG0688	phosphatidylethanolamine metabolic process
DGM81_13640	COG0433	COG0433 Predicted ATPase
DGM81_13665	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DGM81_13670	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DGM81_13695	COG0717	Belongs to the dCTP deaminase family
DGM81_13705	COG0489	protein tyrosine kinase activity
DGM81_13745	COG3590	peptidase
DGM81_13770	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DGM81_13775	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DGM81_13780	COG2311	Membrane
DGM81_13785	COG1047	Peptidyl-prolyl cis-trans
DGM81_13790	COG0791	NLP P60 protein
DGM81_13795	COG0791	NLP P60 protein
DGM81_13805	COG4106	trans-aconitate 2-methyltransferase activity
DGM81_13810	COG1301	dicarboxylic acid transport
DGM81_13815	COG1785	Belongs to the alkaline phosphatase family
DGM81_13825	COG0037	tRNA processing
DGM81_13830	COG1722	exodeoxyribonuclease VII activity
DGM81_13835	COG0142	geranyltranstransferase activity
DGM81_13840	COG4104	PAAR repeat-containing protein
DGM81_13850	COG0312	modulator of DNA gyrase
DGM81_13855	COG3028	Belongs to the UPF0307 family
DGM81_13860	COG0312	modulator of DNA gyrase
DGM81_13870	COG3164	Protein of unknown function
DGM81_13880	COG0424	maF-like protein
DGM81_13885	COG2968	Membrane
DGM81_13900	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
DGM81_13915	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DGM81_13935	COG0495	leucyl-tRNA aminoacylation
DGM81_13945	COG3118	belongs to the thioredoxin family
DGM81_13970	COG2155	Conserved Protein
DGM81_14020	COG1132	(ABC) transporter
DGM81_14050	COG0745	RESPONSE REGULATOR receiver
DGM81_14055	COG5000	phosphorelay sensor kinase activity
DGM81_14055	COG5002	protein histidine kinase activity
DGM81_14060	COG0475	glutathione-regulated potassium exporter activity
DGM81_14070	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
DGM81_14090	COG1187	pseudouridine synthase activity
DGM81_14095	COG5001	Diguanylate cyclase
DGM81_14095	COG5002	protein histidine kinase activity
DGM81_14105	COG1595	DNA-templated transcription, initiation
DGM81_14225	COG0667	Aldo Keto reductase
DGM81_14230	COG2814	Major facilitator Superfamily
DGM81_14235	COG0583	DNA-binding transcription factor activity
DGM81_14245	COG2207	Transcriptional regulator
DGM81_14255	COG1309	transcriptional regulator
DGM81_14265	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DGM81_14280	COG0735	belongs to the Fur family
DGM81_14285	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DGM81_14310	COG4452	Inner membrane protein CreD
DGM81_14330	COG0745	RESPONSE REGULATOR receiver
DGM81_14335	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
DGM81_14345	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DGM81_14355	COG0643	Histidine kinase
DGM81_14355	COG2198	Histidine kinase
DGM81_14360	COG0840	transmembrane signaling receptor activity
DGM81_14365	COG0835	chemotaxis
DGM81_14370	COG2202	Pas domain
DGM81_14370	COG2200	EAL domain
DGM81_14370	COG2199	diguanylate cyclase activity
DGM81_14375	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
DGM81_14380	COG2201	protein-glutamate methylesterase activity
DGM81_14390	COG3590	peptidase
DGM81_14405	COG1515	deoxyribonuclease V activity
DGM81_14415	COG1741	Belongs to the pirin family
DGM81_14430	COG1741	Belongs to the pirin family
DGM81_14435	COG1966	Carbon starvation protein
DGM81_14440	COG2879	small protein
DGM81_14485	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
DGM81_14490	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DGM81_14495	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
DGM81_14500	COG2080	2 iron, 2 sulfur cluster binding
DGM81_14505	COG0604	alcohol dehydrogenase
DGM81_14505	COG1028	Short-chain dehydrogenase reductase Sdr
DGM81_14505	COG3321	synthase
DGM81_14510	COG5001	Diguanylate cyclase
DGM81_14510	COG4251	negative regulation of phosphorylation
DGM81_14510	COG3706	GGDEF domain
DGM81_14510	COG2203	Gaf domain
DGM81_14515	COG0629	single-stranded DNA binding
DGM81_14520	COG0142	geranyltranstransferase activity
DGM81_14530	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DGM81_14545	COG0527	aspartate kinase activity
DGM81_14550	COG0384	phenazine biosynthesis protein PhzF
DGM81_14555	COG0384	phenazine biosynthesis protein PhzF
DGM81_14565	COG1764	response to oxidative stress
DGM81_14570	COG0540	Belongs to the ATCase OTCase family
DGM81_14575	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DGM81_14580	COG1678	Uncharacterized ACR, COG1678
DGM81_14585	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
DGM81_14590	COG0519	Catalyzes the synthesis of GMP from XMP
DGM81_14615	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DGM81_14630	COG0739	heme binding
DGM81_14650	COG0693	protein deglycase activity
DGM81_14660	COG1959	2 iron, 2 sulfur cluster binding
DGM81_14665	COG0719	Fe-S assembly protein
DGM81_14670	COG0396	ATPase activity
DGM81_14675	COG0719	Fe-S assembly protein
DGM81_14680	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DGM81_14690	COG0456	acetyltransferase
DGM81_14695	COG2146	nitrite reductase [NAD(P)H] activity
DGM81_14700	COG4774	siderophore transport
DGM81_14705	COG3128	pkhd-type hydroxylase
DGM81_14730	COG3328	transposase activity
DGM81_14735	COG1477	protein flavinylation
DGM81_14740	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
DGM81_14750	COG1555	photosystem II stabilization
DGM81_14770	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DGM81_14780	COG0628	permease
DGM81_14790	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
DGM81_14805	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DGM81_14825	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DGM81_14830	COG0271	Belongs to the BolA IbaG family
DGM81_14840	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
DGM81_14850	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
DGM81_14855	COG1137	ATPase activity
DGM81_14870	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DGM81_14875	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
DGM81_14880	COG1660	Displays ATPase and GTPase activities
DGM81_14890	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DGM81_14895	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DGM81_14905	COG2239	Acts as a magnesium transporter
DGM81_14970	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DGM81_14970	COG0551	DNA topoisomerase type I activity
DGM81_14990	COG2951	lytic endotransglycosylase activity
DGM81_15040	COG1113	amino acid transport
DGM81_15075	COG2197	response regulator
DGM81_15080	COG0531	amino acid
DGM81_15170	COG2814	Major facilitator Superfamily
DGM81_15180	COG0754	glutathionylspermidine amidase activity
DGM81_15205	COG1842	Phage shock protein A
DGM81_15215	COG0259	pyridoxamine-phosphate oxidase activity
DGM81_15220	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DGM81_15225	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DGM81_15235	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
DGM81_15240	COG2814	Major facilitator Superfamily
DGM81_15265	COG2198	Histidine kinase
DGM81_15265	COG0784	Response regulator, receiver
DGM81_15265	COG2205	protein histidine kinase activity
DGM81_15270	COG2353	YceI-like domain
DGM81_15290	COG1760	l-serine dehydratase
DGM81_15300	COG0460	homoserine dehydrogenase
DGM81_15300	COG0527	aspartate kinase activity
DGM81_15305	COG0626	cystathionine gamma-synthase activity
DGM81_15310	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DGM81_15315	COG0739	heme binding
DGM81_15320	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
DGM81_15325	COG1272	protein, Hemolysin III
DGM81_15330	COG2982	Protein involved in outer membrane biogenesis
DGM81_15335	COG0516	GMP reductase activity
DGM81_15335	COG0517	IMP dehydrogenase activity
DGM81_15340	COG0463	Glycosyl transferase, family 2
DGM81_15345	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DGM81_15350	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
DGM81_15360	COG4771	TonB-dependent receptor
DGM81_15365	COG1309	transcriptional regulator
DGM81_15375	COG1960	acyl-CoA dehydrogenase activity
DGM81_15400	COG3328	transposase activity
DGM81_15430	COG0509	glycine decarboxylation via glycine cleavage system
DGM81_15435	COG0404	The glycine cleavage system catalyzes the degradation of glycine
DGM81_15445	COG0330	HflC and HflK could
DGM81_15450	COG1742	UPF0060 membrane protein
DGM81_15455	COG3956	TIGRFAM MazG family protein
DGM81_15465	COG0494	nUDIX hydrolase
DGM81_15475	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DGM81_15480	COG0837	glucose binding
DGM81_15515	COG3328	transposase activity
DGM81_15530	COG1472	Belongs to the glycosyl hydrolase 3 family
DGM81_15540	COG3537	Alpha-1,2-mannosidase
DGM81_15585	COG3142	Participates in the control of copper homeostasis
DGM81_15590	COG1446	asparaginase
DGM81_15620	COG0643	Histidine kinase
DGM81_15620	COG0784	Response regulator, receiver
DGM81_15620	COG2198	Histidine kinase
DGM81_15625	COG0840	transmembrane signaling receptor activity
DGM81_15630	COG0835	chemotaxis
DGM81_15645	COG0189	ligase activity
DGM81_15655	COG1397	ADP-ribosylglycohydrolase
DGM81_15665	COG1199	ATP-dependent helicase activity
DGM81_15675	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DGM81_15680	COG1215	transferase activity, transferring glycosyl groups
DGM81_15695	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DGM81_15705	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
DGM81_15710	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
DGM81_15715	COG0535	radical SAM domain protein
DGM81_15720	COG0535	radical SAM domain protein
DGM81_15735	COG0837	glucose binding
DGM81_15745	COG3328	transposase activity
DGM81_15755	COG1643	Atp-dependent helicase
DGM81_15760	COG0783	Belongs to the Dps family
DGM81_15765	COG0514	ATP-dependent DNA helicase (RecQ)
DGM81_15805	COG0840	transmembrane signaling receptor activity
DGM81_15825	COG3920	Histidine kinase
DGM81_15830	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
DGM81_15840	COG0602	queuosine metabolic process
DGM81_15850	COG2885	chlorophyll binding
DGM81_15855	COG0823	Involved in the tonB-independent uptake of proteins
DGM81_15865	COG0848	biopolymer transport protein
DGM81_15875	COG0824	Thioesterase
DGM81_15880	COG2255	four-way junction helicase activity
DGM81_15890	COG3158	transport of potassium into the cell
DGM81_15895	COG0632	four-way junction helicase activity
DGM81_15900	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
DGM81_15905	COG0217	transcriptional regulatory protein
DGM81_15920	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
DGM81_15935	COG0477	Major facilitator Superfamily
DGM81_15960	COG0657	acetylesterase activity
DGM81_15960	COG2755	lipolytic protein G-D-S-L family
DGM81_15980	COG0488	(ABC) transporter
DGM81_16015	COG4651	solute:proton antiporter activity
DGM81_16015	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DGM81_16040	COG4772	TonB-dependent receptor
DGM81_16050	COG4264	IucA IucC family
DGM81_16065	COG0019	diaminopimelate decarboxylase activity
DGM81_16090	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
DGM81_16100	COG1492	cobalamin metabolic process
DGM81_16110	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
DGM81_16130	COG4206	TonB-dependent receptor
DGM81_16140	COG0542	response to heat
DGM81_16190	COG1877	trehalose-phosphatase activity
DGM81_16195	COG3387	PFAM Glycoside hydrolase 15-related
DGM81_16205	COG4993	Dehydrogenase
DGM81_16225	COG0840	transmembrane signaling receptor activity
DGM81_16230	COG3011	Protein conserved in bacteria
DGM81_16245	COG0564	pseudouridine synthase activity
DGM81_16250	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DGM81_16260	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
DGM81_16260	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DGM81_16275	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
DGM81_16280	COG0045	succinate-CoA ligase (ADP-forming) activity
DGM81_16330	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
DGM81_16335	COG0237	dephospho-CoA kinase activity
DGM81_16365	COG0745	RESPONSE REGULATOR receiver
DGM81_16375	COG0189	ligase activity
DGM81_16415	COG2003	Belongs to the UPF0758 family
DGM81_16430	COG3328	transposase activity
DGM81_16485	COG5001	Diguanylate cyclase
DGM81_16565	COG0583	DNA-binding transcription factor activity
DGM81_16570	COG1396	sequence-specific DNA binding
DGM81_16580	COG3328	transposase activity
DGM81_16600	COG0582	viral genome integration into host DNA
DGM81_16620	COG2022	thiamine diphosphate biosynthetic process
DGM81_16625	COG0220	tRNA (guanine-N7-)-methyltransferase activity
DGM81_16630	COG0471	metal ion transport
DGM81_16630	COG3273	potassium ion transport
DGM81_16655	COG1970	mechanosensitive ion channel activity
DGM81_16665	COG1609	Transcriptional regulator
DGM81_16675	COG3250	beta-galactosidase activity
DGM81_16680	COG4948	Mandelate Racemase Muconate Lactonizing
DGM81_16690	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DGM81_16700	COG0308	aminopeptidase N
DGM81_16705	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DGM81_16715	COG0529	Catalyzes the synthesis of activated sulfate
DGM81_16715	COG2895	sulfate adenylyltransferase (ATP) activity
DGM81_16720	COG0175	sulfate reduction
DGM81_16725	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
DGM81_16730	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DGM81_16735	COG0175	sulfate reduction
DGM81_16755	COG2205	protein histidine kinase activity
DGM81_16755	COG2198	Histidine kinase
DGM81_16755	COG0784	Response regulator, receiver
DGM81_16775	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DGM81_16775	COG1648	precorrin-2 dehydrogenase activity
DGM81_16790	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
DGM81_16795	COG3588	fructose-bisphosphate aldolase
DGM81_16805	COG0469	pyruvate kinase activity
DGM81_16815	COG0126	phosphoglycerate kinase activity
DGM81_16845	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DGM81_16855	COG3047	cAMP biosynthetic process
DGM81_16870	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DGM81_16870	COG3453	Protein conserved in bacteria
DGM81_16875	COG0725	ABC transporter, periplasmic molybdate-binding protein
DGM81_16880	COG4149	molybdate abc transporter
DGM81_16885	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
DGM81_16905	COG0642	Histidine kinase
DGM81_16930	COG1022	Amp-dependent synthetase and ligase
DGM81_16955	COG1376	ErfK ybiS ycfS ynhG family protein
DGM81_16960	COG0739	heme binding
DGM81_16965	COG4773	Receptor
DGM81_16980	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DGM81_16985	COG1301	dicarboxylic acid transport
DGM81_16995	COG2304	oxidoreductase activity
DGM81_17015	COG0714	Associated with various cellular activities
DGM81_17045	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
DGM81_17065	COG1957	nucleoside hydrolase
DGM81_17070	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DGM81_17080	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DGM81_17095	COG1561	YicC-like family, N-terminal region
DGM81_17100	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
DGM81_17110	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DGM81_17115	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DGM81_17130	COG0006	proline dipeptidase activity
DGM81_17140	COG0006	proline dipeptidase activity
DGM81_17145	COG3079	Belongs to the UPF0149 family
DGM81_17165	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DGM81_17185	COG2912	Transglutaminase-like superfamily
DGM81_17195	COG1773	rubredoxin
DGM81_17200	COG0352	thiamine-phosphate diphosphorylase activity
DGM81_17235	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DGM81_17245	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
DGM81_17250	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DGM81_17280	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DGM81_17285	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DGM81_17290	COG1028	Short-chain dehydrogenase reductase Sdr
DGM81_17300	COG0671	phosphoesterase, PA-phosphatase related
DGM81_17310	COG3781	membrane
DGM81_17320	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DGM81_17325	COG0563	adenylate kinase activity
DGM81_17340	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
DGM81_17350	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
DGM81_17365	COG3328	transposase activity
DGM81_17375	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
DGM81_17390	COG0840	transmembrane signaling receptor activity
DGM81_17395	COG0405	Gamma-glutamyltransferase
DGM81_17400	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DGM81_17420	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DGM81_17430	COG0473	3-isopropylmalate dehydrogenase activity
DGM81_17435	COG0066	3-isopropylmalate dehydratase activity
DGM81_17440	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DGM81_17460	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DGM81_17465	COG1538	Outer membrane efflux protein
DGM81_17470	COG1519	Transferase
DGM81_17475	COG1560	Kdo2-lipid A biosynthetic process
DGM81_17500	COG0280	phosphate acetyltransferase
DGM81_17500	COG0281	malic enzyme
DGM81_17505	COG1301	dicarboxylic acid transport
DGM81_17530	COG0583	DNA-binding transcription factor activity
DGM81_17535	COG0667	Aldo Keto reductase
DGM81_17550	COG2197	response regulator
DGM81_17565	COG0642	Histidine kinase
DGM81_17585	COG2851	Citrate transporter
DGM81_17590	COG1028	Short-chain dehydrogenase reductase Sdr
DGM81_17595	COG1609	Transcriptional regulator
DGM81_17600	COG2211	Major facilitator Superfamily
DGM81_17625	COG1162	GTPase activity
DGM81_17630	COG0436	Aminotransferase
DGM81_17645	COG0726	polysaccharide deacetylase
DGM81_17650	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
DGM81_17665	COG3964	amidohydrolase
DGM81_17670	COG0402	S-adenosylhomocysteine deaminase activity
DGM81_17700	COG3328	transposase activity
DGM81_17710	COG1012	belongs to the aldehyde dehydrogenase family
DGM81_17715	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DGM81_17725	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DGM81_17740	COG0218	Necessary for normal cell division and for the maintenance of normal septation
DGM81_17755	COG2205	protein histidine kinase activity
DGM81_17785	COG3791	Glutathione-dependent formaldehyde-activating
DGM81_17805	COG1307	EDD domain protein, DegV family
DGM81_17820	COG3328	transposase activity
DGM81_17845	COG1183	phosphatidylcholine synthase activity
DGM81_17855	COG0442	prolyl-tRNA aminoacylation
DGM81_17870	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
DGM81_17875	COG1127	ABC transporter
DGM81_17880	COG3218	ABC-type transport auxiliary lipoprotein component
DGM81_17880	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
DGM81_17910	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DGM81_17915	COG0662	Cupin 2, conserved barrel domain protein
DGM81_17915	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
DGM81_17945	COG2086	electron transfer activity
DGM81_17960	COG0546	phosphoglycolate phosphatase activity
DGM81_17960	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
DGM81_17965	COG0277	FAD linked oxidase domain protein
DGM81_17975	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DGM81_17995	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DGM81_18000	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
DGM81_18005	COG0438	transferase activity, transferring glycosyl groups
DGM81_18025	COG0438	transferase activity, transferring glycosyl groups
DGM81_18035	COG0626	cystathionine gamma-synthase activity
DGM81_18065	COG0625	glutathione transferase activity
DGM81_18080	COG0513	Belongs to the DEAD box helicase family
DGM81_18085	COG0720	synthase
DGM81_18095	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
DGM81_18105	COG1956	GAF domain-containing protein
DGM81_18120	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DGM81_18125	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DGM81_18135	COG4991	sh3 domain protein
DGM81_18145	COG0339	signal peptide processing
DGM81_18160	COG2132	Multicopper oxidase
DGM81_18195	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DGM81_18200	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DGM81_18205	COG1136	(ABC) transporter
DGM81_18210	COG0577	efflux transmembrane transporter activity
DGM81_18210	COG1136	(ABC) transporter
DGM81_18230	COG4191	Histidine kinase
DGM81_18235	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DGM81_18250	COG0355	proton-transporting ATP synthase activity, rotational mechanism
DGM81_18255	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DGM81_18260	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DGM81_18265	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DGM81_18270	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DGM81_18285	COG0356	it plays a direct role in the translocation of protons across the membrane
DGM81_18305	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DGM81_18315	COG0508	dehydrogenase complex catalyzes the overall conversion of
DGM81_18355	COG2011	ABC-type metal ion transport system permease component
DGM81_18360	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DGM81_18365	COG0697	spore germination
DGM81_18370	COG1666	GTP binding
DGM81_18380	COG5002	protein histidine kinase activity
DGM81_18380	COG2198	Histidine kinase
DGM81_18380	COG0784	Response regulator, receiver
DGM81_18405	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DGM81_18410	COG1187	pseudouridine synthase activity
DGM81_18415	COG2813	Specifically methylates the guanine in position
DGM81_18430	COG3039	Transposase
DGM81_18440	COG3328	transposase activity
DGM81_18460	COG2202	Pas domain
DGM81_18460	COG2205	protein histidine kinase activity
DGM81_18480	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DGM81_18485	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DGM81_18540	COG0842	Transport permease protein
DGM81_18545	COG1131	(ABC) transporter
DGM81_18550	COG0025	NhaP-type Na H and K H
DGM81_18560	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
DGM81_18565	COG1573	uracil-dna glycosylase
DGM81_18575	COG3384	dioxygenase
DGM81_18585	COG0583	DNA-binding transcription factor activity
DGM81_18595	COG0667	Aldo Keto reductase
DGM81_18610	COG3590	peptidase
DGM81_18625	COG0531	amino acid
DGM81_18640	COG2972	Histidine kinase
DGM81_18660	COG3685	Protein conserved in bacteria
DGM81_18665	COG3546	catalase activity
DGM81_18715	COG1271	oxidase subunit
DGM81_18735	COG1028	Short-chain dehydrogenase reductase Sdr
DGM81_18755	COG1063	alcohol dehydrogenase
DGM81_18765	COG3328	transposase activity
DGM81_18785	COG3039	Transposase
DGM81_18800	COG0772	Belongs to the SEDS family
DGM81_18815	COG1792	Involved in formation and maintenance of cell shape
DGM81_18820	COG1077	Cell shape determining protein MreB Mrl
DGM81_18825	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DGM81_18840	COG3284	Transcriptional regulator
DGM81_18890	COG0308	aminopeptidase N
DGM81_18895	COG3300	MHYT domain
DGM81_18895	COG5001	Diguanylate cyclase
DGM81_18900	COG2226	methyltransferase
DGM81_18930	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
DGM81_18935	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
DGM81_18940	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
DGM81_18950	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
DGM81_18960	COG2832	Protein of unknown function (DUF454)
DGM81_18970	COG0436	Aminotransferase
DGM81_18980	COG1505	serine-type exopeptidase activity
DGM81_19020	COG0181	hydroxymethylbilane synthase activity
DGM81_19030	COG3275	phosphorelay sensor kinase activity
DGM81_19040	COG2943	transferase activity, transferring hexosyl groups
DGM81_19090	COG0784	Response regulator, receiver
DGM81_19090	COG2205	protein histidine kinase activity
DGM81_19095	COG3328	transposase activity
DGM81_19110	COG3447	MASE1 domain protein
DGM81_19110	COG5001	Diguanylate cyclase
DGM81_19110	COG5002	protein histidine kinase activity
DGM81_19155	COG0598	Magnesium transport protein CorA
DGM81_19165	COG1113	amino acid transport
DGM81_19190	COG5297	Belongs to the glycosyl hydrolase family 6
DGM81_19195	COG4305	rare lipoprotein A
DGM81_19200	COG0697	spore germination
DGM81_19225	COG1959	2 iron, 2 sulfur cluster binding
DGM81_19305	COG0435	Glutathione S-transferase
DGM81_19315	COG4221	oxidoreductase activity
DGM81_19345	COG4221	oxidoreductase activity
DGM81_19360	COG3328	transposase activity
DGM81_19410	COG1802	Transcriptional regulator
DGM81_19420	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DGM81_19445	COG3052	prosthetic group binding
DGM81_19480	COG2353	YceI-like domain
DGM81_19485	COG0778	Nitroreductase
DGM81_19505	COG3039	Transposase
DGM81_19525	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
DGM81_19530	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
DGM81_19540	COG3386	PFAM SMP-30 Gluconolaconase
DGM81_19555	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DGM81_19560	COG3550	peptidyl-serine autophosphorylation
DGM81_19575	COG0459	protein refolding
DGM81_19595	COG1324	tolerance protein
DGM81_19605	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
DGM81_19610	COG0511	ligase activity, forming carbon-carbon bonds
DGM81_19620	COG0439	Biotin carboxylase
DGM81_19640	COG2264	protein methyltransferase activity
DGM81_19665	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
DGM81_19670	COG4589	Belongs to the CDS family
DGM81_19695	COG0671	phosphoesterase, PA-phosphatase related
DGM81_19695	COG2453	phosphatase
DGM81_19700	COG2267	carboxylic ester hydrolase activity
DGM81_19705	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DGM81_19710	COG0138	bifunctional purine biosynthesis protein purh
DGM81_19720	COG0151	Belongs to the GarS family
DGM81_19730	COG1289	transmembrane transporter activity
DGM81_19735	COG2814	Major facilitator Superfamily
DGM81_19745	COG2814	Major facilitator Superfamily
DGM81_19760	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
DGM81_19775	COG0316	Belongs to the HesB IscA family
DGM81_19815	COG1051	belongs to the nudix hydrolase family
DGM81_19830	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
DGM81_19840	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
DGM81_19850	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
DGM81_19855	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DGM81_19865	COG0134	indole-3-glycerol-phosphate synthase activity
DGM81_19870	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DGM81_19895	COG1597	lipid kinase activity
DGM81_19915	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
DGM81_19920	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
DGM81_19940	COG3179	chitinase
DGM81_19960	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DGM81_19960	COG2111	Na H antiporter
DGM81_19965	COG1006	Multisubunit Na H antiporter MnhC subunit
DGM81_19970	COG0651	ATP synthesis coupled electron transport
DGM81_19980	COG2212	antiporter activity
DGM81_19985	COG1320	monovalent cation:proton antiporter activity
DGM81_20005	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
DGM81_20010	COG2852	Protein conserved in bacteria
DGM81_20030	COG3104	oligopeptide transport
DGM81_20035	COG3483	tryptophan 2,3-dioxygenase activity
DGM81_20045	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DGM81_20060	COG0508	dehydrogenase complex catalyzes the overall conversion of
DGM81_20065	COG0513	Belongs to the DEAD box helicase family
DGM81_20075	COG1028	Short-chain dehydrogenase reductase Sdr
DGM81_20080	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DGM81_20115	COG1028	Short-chain dehydrogenase reductase Sdr
DGM81_20125	COG3039	Transposase
DGM81_20135	COG3328	transposase activity
DGM81_20160	COG0702	epimerase
DGM81_20185	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
DGM81_20190	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
DGM81_20195	COG0297	glycogen (starch) synthase activity
DGM81_20205	COG2354	Protein conserved in bacteria
DGM81_20210	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
DGM81_20215	COG1368	sulfuric ester hydrolase activity
DGM81_20220	COG1511	domain protein
DGM81_20220	COG3264	Mechanosensitive ion channel
DGM81_20295	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DGM81_20365	COG3039	Transposase
DGM81_20395	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
DGM81_20400	COG1040	competence protein
DGM81_20405	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
DGM81_20410	COG0156	8-amino-7-oxononanoate synthase activity
DGM81_20420	COG2267	carboxylic ester hydrolase activity
DGM81_20455	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DGM81_20465	COG0445	tRNA wobble uridine modification
DGM81_20475	COG0657	acetylesterase activity
DGM81_20485	COG1414	Transcriptional regulator
DGM81_20495	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DGM81_20500	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DGM81_20510	COG3485	protocatechuate 3,4-dioxygenase
DGM81_20515	COG3485	protocatechuate 3,4-dioxygenase
DGM81_20530	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
DGM81_20555	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DGM81_20560	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DGM81_20570	COG3328	transposase activity
DGM81_20620	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
DGM81_20635	COG0129	dihydroxy-acid dehydratase activity
DGM81_20690	COG1733	regulation of RNA biosynthetic process
DGM81_20695	COG0702	epimerase
DGM81_20735	COG0583	DNA-binding transcription factor activity
DGM81_20740	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DGM81_20765	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DGM81_20770	COG2205	protein histidine kinase activity
DGM81_20775	COG0745	RESPONSE REGULATOR receiver
DGM81_20795	COG1902	pentaerythritol trinitrate reductase activity
DGM81_20800	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DGM81_20815	COG2814	Major facilitator Superfamily
DGM81_20820	COG0583	DNA-binding transcription factor activity
DGM81_20835	COG0084	hydrolase, TatD family'
DGM81_20860	COG2252	PERMEase
DGM81_20900	COG0583	DNA-binding transcription factor activity
DGM81_20910	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
DGM81_20930	COG2072	flavoprotein involved in K transport
DGM81_20940	COG4807	Protein conserved in bacteria
DGM81_20955	COG1643	Atp-dependent helicase
DGM81_20965	COG1187	pseudouridine synthase activity
DGM81_20980	COG2130	NADP-dependent
DGM81_21000	COG1764	response to oxidative stress
DGM81_21005	COG1846	Transcriptional regulator
DGM81_21010	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
DGM81_21020	COG0697	spore germination
DGM81_21085	COG1960	acyl-CoA dehydrogenase activity
DGM81_21090	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DGM81_21095	COG4770	biotin carboxylase activity
DGM81_21110	COG3328	transposase activity
DGM81_21125	COG3039	Transposase
DGM81_21145	COG2224	Isocitrate lyase
DGM81_21150	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
DGM81_21155	COG0583	DNA-binding transcription factor activity
DGM81_21160	COG0475	glutathione-regulated potassium exporter activity
DGM81_21195	COG0339	signal peptide processing
DGM81_21200	COG1446	asparaginase
DGM81_21230	COG0564	pseudouridine synthase activity
DGM81_21240	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
DGM81_21255	COG1181	Belongs to the D-alanine--D-alanine ligase family
DGM81_21270	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DGM81_21275	COG0318	PFAM AMP-dependent synthetase and ligase
DGM81_21280	COG0727	PFAM Uncharacterised protein family (UPF0153)
DGM81_21285	COG0596	Alpha beta hydrolase
DGM81_21290	COG3177	Filamentation induced by cAMP protein fic
DGM81_21295	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DGM81_21310	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
DGM81_21335	COG2205	protein histidine kinase activity
DGM81_21370	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
DGM81_21375	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
DGM81_21380	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DGM81_21420	COG0183	Belongs to the thiolase family
DGM81_21435	COG2032	superoxide dismutase activity
DGM81_21440	COG2032	superoxide dismutase activity
DGM81_21445	COG2204	response regulator
DGM81_21450	COG3852	Histidine kinase
DGM81_21455	COG0004	ammonium transporteR
DGM81_21460	COG0347	Belongs to the P(II) protein family
DGM81_21465	COG0174	glutamine synthetase
DGM81_21475	COG1968	undecaprenyl-diphosphatase activity
DGM81_21520	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DGM81_21530	COG2062	phosphohistidine phosphatase, SixA
DGM81_21535	COG0489	protein tyrosine kinase activity
DGM81_21565	COG1262	PFAM Formylglycine-generating sulfatase enzyme
DGM81_21580	COG0517	IMP dehydrogenase activity
DGM81_21580	COG1125	glycine betaine transport
DGM81_21595	COG1119	ATPase activity
DGM81_21605	COG1752	Esterase of the alpha-beta hydrolase superfamily
DGM81_21615	COG1522	sequence-specific DNA binding
DGM81_21620	COG3186	Phenylalanine-4-hydroxylase
DGM81_21630	COG2755	lipolytic protein G-D-S-L family
DGM81_21640	COG1028	Short-chain dehydrogenase reductase Sdr
DGM81_21645	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
DGM81_21650	COG1609	Transcriptional regulator
DGM81_21655	COG3507	Belongs to the glycosyl hydrolase 43 family
DGM81_21670	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
DGM81_21680	COG2755	lipolytic protein G-D-S-L family
DGM81_21680	COG0657	acetylesterase activity
DGM81_21700	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
DGM81_21705	COG0366	Alpha amylase catalytic
DGM81_21710	COG0366	Alpha amylase catalytic
DGM81_21725	COG3039	Transposase
DGM81_21730	COG3039	Transposase
DGM81_21735	COG3039	Transposase
DGM81_21755	COG3328	transposase activity
DGM81_21820	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
DGM81_21850	COG2197	response regulator
DGM81_21855	COG4585	Histidine kinase
DGM81_21860	COG1755	Isoprenylcysteine carboxyl methyltransferase
DGM81_21865	COG1304	FMN binding
DGM81_21895	COG4772	TonB-dependent receptor
DGM81_21905	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
DGM81_21950	COG0714	Associated with various cellular activities
DGM81_21990	COG0477	Major facilitator Superfamily
DGM81_22000	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DGM81_22045	COG3237	CsbD-like
DGM81_22050	COG3039	Transposase
DGM81_22065	COG3039	Transposase
DGM81_22080	COG2249	NAD(P)H dehydrogenase (quinone) activity
DGM81_22120	COG1028	Short-chain dehydrogenase reductase Sdr
DGM81_22125	COG0300	oxidoreductase activity
DGM81_22145	COG1272	protein, Hemolysin III
DGM81_22150	COG1111	helicase
DGM81_22150	COG1205	dead DEAH box helicase
DGM81_22240	COG0067	glutamate synthase
DGM81_22240	COG0069	glutamate synthase activity
DGM81_22240	COG0070	glutamate synthase
DGM81_22245	COG0493	'glutamate synthase
DGM81_22260	COG1064	alcohol dehydrogenase
DGM81_22270	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
DGM81_22280	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
DGM81_22285	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
DGM81_22295	COG2234	aminopeptidase activity
DGM81_22305	COG4942	peptidase
DGM81_22310	COG0793	Belongs to the peptidase S41A family
DGM81_22355	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DGM81_22365	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
DGM81_22395	COG3328	transposase activity
DGM81_22460	COG1028	Short-chain dehydrogenase reductase Sdr
DGM81_22490	COG0439	Biotin carboxylase
DGM81_22540	COG0386	Belongs to the glutathione peroxidase family
DGM81_22550	COG1322	Protein conserved in bacteria
DGM81_22560	COG0583	DNA-binding transcription factor activity
DGM81_22580	COG0531	amino acid
DGM81_22605	COG2199	diguanylate cyclase activity
DGM81_22605	COG2203	Gaf domain
DGM81_22610	COG3835	regulator
DGM81_22615	COG1929	Belongs to the glycerate kinase type-1 family
DGM81_22635	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
DGM81_22645	COG0861	Integral membrane protein TerC family
DGM81_22665	COG0584	glycerophosphoryl diester phosphodiesterase
DGM81_22680	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
DGM81_22685	COG0726	polysaccharide deacetylase
DGM81_22690	COG0706	membrane insertase activity
DGM81_22695	COG0594	ribonuclease P activity
DGM81_22820	COG3328	transposase activity
DGM81_22865	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
DGM81_22870	COG4691	Plasmid stability protein
DGM81_22875	COG1487	ribonuclease activity
DGM81_22945	COG3846	protein secretion by the type IV secretion system
DGM81_22955	COG3451	type IV secretory pathway VirB4
DGM81_22970	COG4962	Type ii secretion system protein e
DGM81_23090	COG3328	transposase activity
DGM81_23130	COG3039	Transposase
DGM81_23310	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
DGM81_23315	COG4691	Plasmid stability protein
DGM81_23320	COG1487	ribonuclease activity