locus-tag	class	description
NG825_00010	COG0592	DNA-directed DNA polymerase activity
NG825_00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NG825_00020	COG0187	DNA topoisomerase II activity
NG825_00025	COG1266	CAAX protease self-immunity
NG825_00030	COG0501	Belongs to the peptidase M48B family
NG825_00075	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NG825_00090	COG0655	NAD(P)H dehydrogenase (quinone) activity
NG825_00120	COG4772	TonB-dependent receptor
NG825_00145	COG1012	belongs to the aldehyde dehydrogenase family
NG825_00175	COG1304	FMN binding
NG825_00180	COG2186	Transcriptional regulator
NG825_00195	COG4585	Histidine kinase
NG825_00200	COG2197	response regulator
NG825_00355	COG4771	TonB-dependent receptor
NG825_00360	COG1629	transport
NG825_00360	COG4774	siderophore transport
NG825_00390	COG2755	lipolytic protein G-D-S-L family
NG825_00390	COG0657	acetylesterase activity
NG825_00400	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
NG825_00415	COG1609	Transcriptional regulator
NG825_00425	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
NG825_00430	COG1028	Short-chain dehydrogenase reductase Sdr
NG825_00460	COG3186	Phenylalanine-4-hydroxylase
NG825_00465	COG1522	sequence-specific DNA binding
NG825_00475	COG1752	Esterase of the alpha-beta hydrolase superfamily
NG825_00495	COG0840	transmembrane signaling receptor activity
NG825_00510	COG0861	Integral membrane protein TerC family
NG825_00515	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
NG825_00530	COG1929	Belongs to the glycerate kinase type-1 family
NG825_00545	COG0531	amino acid
NG825_00550	COG4566	intracellular signal transduction
NG825_00555	COG4191	Histidine kinase
NG825_00560	COG1285	pathogenesis
NG825_00570	COG1322	Protein conserved in bacteria
NG825_00575	COG0386	Belongs to the glutathione peroxidase family
NG825_00585	COG2853	Lipoprotein
NG825_00600	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
NG825_00605	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
NG825_00610	COG1127	ABC transporter
NG825_00645	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
NG825_00650	COG1074	ATP-dependent DNA helicase activity
NG825_00655	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NG825_00710	COG0840	transmembrane signaling receptor activity
NG825_00720	COG0477	Major facilitator Superfamily
NG825_00725	COG0302	gtp cyclohydrolase
NG825_00755	COG2951	lytic endotransglycosylase activity
NG825_00780	COG3135	benzoate transporter
NG825_00825	COG1803	Methylglyoxal synthase
NG825_00830	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
NG825_00835	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
NG825_00840	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
NG825_00850	COG0493	'glutamate synthase
NG825_00855	COG0069	glutamate synthase activity
NG825_00855	COG0070	glutamate synthase
NG825_00855	COG0067	glutamate synthase
NG825_00880	COG1028	Short-chain dehydrogenase reductase Sdr
NG825_00935	COG1272	protein, Hemolysin III
NG825_01020	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NG825_01035	COG2062	phosphohistidine phosphatase, SixA
NG825_01045	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NG825_01050	COG2050	protein possibly involved in aromatic compounds catabolism
NG825_01075	COG1968	undecaprenyl-diphosphatase activity
NG825_01080	COG0174	glutamine synthetase
NG825_01085	COG0347	Belongs to the P(II) protein family
NG825_01090	COG0004	ammonium transporteR
NG825_01095	COG3852	Histidine kinase
NG825_01100	COG2204	response regulator
NG825_01105	COG2032	superoxide dismutase activity
NG825_01110	COG2032	superoxide dismutase activity
NG825_01125	COG0183	Belongs to the thiolase family
NG825_01150	COG0456	acetyltransferase
NG825_01165	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
NG825_01170	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
NG825_01180	COG3226	Transcriptional regulator
NG825_01190	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
NG825_01200	COG0612	Peptidase, M16
NG825_01210	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NG825_01220	COG0596	Alpha beta hydrolase
NG825_01230	COG0727	PFAM Uncharacterised protein family (UPF0153)
NG825_01235	COG0318	PFAM AMP-dependent synthetase and ligase
NG825_01240	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NG825_01310	COG1595	DNA-templated transcription, initiation
NG825_01320	COG1446	asparaginase
NG825_01325	COG0339	signal peptide processing
NG825_01330	COG4104	PAAR repeat-containing protein
NG825_01370	COG2224	Isocitrate lyase
NG825_01375	COG3706	GGDEF domain
NG825_01395	COG4297	protein containing double-stranded beta helix domain
NG825_01400	COG0659	secondary active sulfate transmembrane transporter activity
NG825_01430	COG1024	Enoyl-CoA hydratase
NG825_01435	COG1022	Amp-dependent synthetase and ligase
NG825_01445	COG2814	Major facilitator Superfamily
NG825_01510	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
NG825_01525	COG3485	protocatechuate 3,4-dioxygenase
NG825_01535	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NG825_01540	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NG825_01545	COG1414	Transcriptional regulator
NG825_01550	COG2130	NADP-dependent
NG825_01565	COG1187	pseudouridine synthase activity
NG825_01585	COG1643	Atp-dependent helicase
NG825_01590	COG0084	hydrolase, TatD family'
NG825_01690	COG0842	Transport permease protein
NG825_01695	COG1131	(ABC) transporter
NG825_01700	COG0543	2 iron, 2 sulfur cluster binding
NG825_01700	COG0633	Ferredoxin
NG825_01710	COG1476	TRANSCRIPTIONal
NG825_01720	COG4555	ABC transporter
NG825_01745	COG0625	glutathione transferase activity
NG825_01825	COG1199	ATP-dependent helicase activity
NG825_01890	COG3511	phospholipase C
NG825_01900	COG0628	permease
NG825_02025	COG0754	glutathionylspermidine amidase activity
NG825_02050	COG0714	Associated with various cellular activities
NG825_02080	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
NG825_02085	COG3420	alginic acid biosynthetic process
NG825_02095	COG0710	3-dehydroquinate dehydratase activity
NG825_02110	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NG825_02115	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NG825_02130	COG0657	acetylesterase activity
NG825_02145	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NG825_02155	COG3023	N-Acetylmuramoyl-L-alanine amidase
NG825_02165	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NG825_02195	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NG825_02200	COG1040	competence protein
NG825_02250	COG2960	long-chain fatty acid transporting porin activity
NG825_02270	COG1166	arginine decarboxylase activity
NG825_02275	COG2755	lipolytic protein G-D-S-L family
NG825_02275	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
NG825_02280	COG0583	DNA-binding transcription factor activity
NG825_02315	COG4221	oxidoreductase activity
NG825_02330	COG2003	Belongs to the UPF0758 family
NG825_02335	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NG825_02345	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NG825_02355	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NG825_02360	COG0708	Exodeoxyribonuclease III
NG825_02365	COG2211	Major facilitator Superfamily
NG825_02380	COG0739	heme binding
NG825_02385	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NG825_02415	COG1064	alcohol dehydrogenase
NG825_02420	COG2234	aminopeptidase activity
NG825_02430	COG4942	peptidase
NG825_02470	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
NG825_02480	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
NG825_02515	COG0840	transmembrane signaling receptor activity
NG825_02535	COG0358	DNA primase activity
NG825_02540	COG1295	ribonuclease BN
NG825_02560	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NG825_02565	COG0668	transmembrane transport
NG825_02570	COG2308	Evidence 4 Homologs of previously reported genes of
NG825_02585	COG4682	membrane
NG825_02590	COG2133	pyrroloquinoline quinone binding
NG825_02615	COG0531	amino acid
NG825_02625	COG1609	Transcriptional regulator
NG825_02650	COG1070	Carbohydrate kinase
NG825_02660	COG1472	Belongs to the glycosyl hydrolase 3 family
NG825_02670	COG3661	Belongs to the glycosyl hydrolase 67 family
NG825_02685	COG1472	Belongs to the glycosyl hydrolase 3 family
NG825_02700	COG4948	Mandelate Racemase Muconate Lactonizing
NG825_02710	COG4771	TonB-dependent receptor
NG825_02715	COG3023	N-Acetylmuramoyl-L-alanine amidase
NG825_02740	COG3409	Peptidoglycan-binding domain 1 protein
NG825_02740	COG3501	Rhs element vgr protein
NG825_02775	COG5383	Protein conserved in bacteria
NG825_02790	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NG825_02795	COG0628	permease
NG825_02820	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NG825_02900	COG0708	Exodeoxyribonuclease III
NG825_02905	COG1418	mRNA catabolic process
NG825_02910	COG4807	Protein conserved in bacteria
NG825_02925	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
NG825_02960	COG1028	Short-chain dehydrogenase reductase Sdr
NG825_02965	COG0179	Fumarylacetoacetate (FAA) hydrolase
NG825_02970	COG4948	Mandelate Racemase Muconate Lactonizing
NG825_02980	COG0738	Major facilitator superfamily
NG825_02985	COG1414	Transcriptional regulator
NG825_03035	COG0604	alcohol dehydrogenase
NG825_03040	COG1196	nuclear chromosome segregation
NG825_03040	COG3264	Mechanosensitive ion channel
NG825_03045	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
NG825_03065	COG2354	Protein conserved in bacteria
NG825_03095	COG1028	Short-chain dehydrogenase reductase Sdr
NG825_03105	COG0513	Belongs to the DEAD box helicase family
NG825_03115	COG0508	dehydrogenase complex catalyzes the overall conversion of
NG825_03145	COG3483	tryptophan 2,3-dioxygenase activity
NG825_03150	COG3104	oligopeptide transport
NG825_03170	COG2852	Protein conserved in bacteria
NG825_03195	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NG825_03200	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NG825_03205	COG1473	amidohydrolase
NG825_03215	COG1652	LysM domain
NG825_03225	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
NG825_03230	COG1349	DNA-binding transcription factor activity
NG825_03240	COG1940	carbohydrate kinase activity
NG825_03250	COG1501	Belongs to the glycosyl hydrolase 31 family
NG825_03260	COG0673	inositol 2-dehydrogenase activity
NG825_03270	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NG825_03275	COG1518	maintenance of DNA repeat elements
NG825_03330	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NG825_03335	COG3118	belongs to the thioredoxin family
NG825_03345	COG2884	Cell division ATP-binding protein ftsE
NG825_03350	COG2177	Part of the ABC transporter FtsEX involved in
NG825_03355	COG2201	protein-glutamate methylesterase activity
NG825_03360	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NG825_03365	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NG825_03370	COG2860	membrane
NG825_03375	COG1252	NADH dehydrogenase
NG825_03395	COG0534	Mate efflux family protein
NG825_03400	COG0616	signal peptide processing
NG825_03410	COG1028	Short-chain dehydrogenase reductase Sdr
NG825_03430	COG0009	L-threonylcarbamoyladenylate synthase
NG825_03435	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NG825_03435	COG1754	DNA topoisomerase type I activity
NG825_03440	COG1714	RDD family
NG825_03455	COG0758	DNA mediated transformation
NG825_03460	COG1652	LysM domain
NG825_03465	COG0242	peptide deformylase activity
NG825_03475	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NG825_03475	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NG825_03515	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NG825_03530	COG1490	D-aminoacyl-tRNA deacylase activity
NG825_03535	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NG825_03550	COG1609	Transcriptional regulator
NG825_03555	COG3537	Alpha-1,2-mannosidase
NG825_03560	COG0366	Alpha amylase catalytic
NG825_03565	COG0366	Alpha amylase catalytic
NG825_03620	COG1191	sigma factor activity
NG825_03650	COG1609	Transcriptional regulator
NG825_03670	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NG825_03675	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NG825_03685	COG5002	protein histidine kinase activity
NG825_03690	COG3038	cytochrome b561
NG825_03695	COG1309	transcriptional regulator
NG825_03720	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NG825_03730	COG2271	Major facilitator Superfamily
NG825_03750	COG0840	transmembrane signaling receptor activity
NG825_03755	COG3546	catalase activity
NG825_03760	COG3685	Protein conserved in bacteria
NG825_03765	COG3685	Protein conserved in bacteria
NG825_03780	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NG825_03830	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NG825_03830	COG1648	precorrin-2 dehydrogenase activity
NG825_03860	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NG825_03870	COG0297	glycogen (starch) synthase activity
NG825_03880	COG2204	response regulator
NG825_03890	COG1335	isochorismatase
NG825_03910	COG0181	hydroxymethylbilane synthase activity
NG825_03925	COG1733	regulation of RNA biosynthetic process
NG825_03940	COG1505	serine-type exopeptidase activity
NG825_03950	COG0436	Aminotransferase
NG825_03960	COG2832	Protein of unknown function (DUF454)
NG825_03970	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NG825_03990	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
NG825_03995	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
NG825_04015	COG2226	methyltransferase
NG825_04025	COG0308	aminopeptidase N
NG825_04035	COG0508	dehydrogenase complex catalyzes the overall conversion of
NG825_04035	COG0596	Alpha beta hydrolase
NG825_04060	COG2010	Cytochrome c
NG825_04080	COG3284	Transcriptional regulator
NG825_04095	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NG825_04100	COG1077	Cell shape determining protein MreB Mrl
NG825_04105	COG1792	Involved in formation and maintenance of cell shape
NG825_04115	COG0768	penicillin binding
NG825_04120	COG0772	Belongs to the SEDS family
NG825_04130	COG5434	Belongs to the glycosyl hydrolase 28 family
NG825_04150	COG1012	belongs to the aldehyde dehydrogenase family
NG825_04155	COG2951	lytic endotransglycosylase activity
NG825_04165	COG1686	Belongs to the peptidase S11 family
NG825_04200	COG0583	DNA-binding transcription factor activity
NG825_04215	COG1056	cytidyltransferase-related domain
NG825_04215	COG1051	belongs to the nudix hydrolase family
NG825_04245	COG1090	epimerase
NG825_04255	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
NG825_04260	COG0673	inositol 2-dehydrogenase activity
NG825_04265	COG2823	Periplasmic or secreted lipoprotein
NG825_04275	COG2205	protein histidine kinase activity
NG825_04280	COG0784	Response regulator, receiver
NG825_04285	COG4191	Histidine kinase
NG825_04295	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NG825_04300	COG1028	Short-chain dehydrogenase reductase Sdr
NG825_04315	COG4305	rare lipoprotein A
NG825_04325	COG2188	Transcriptional regulator
NG825_04330	COG0738	Major facilitator superfamily
NG825_04340	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
NG825_04345	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
NG825_04410	COG0218	Necessary for normal cell division and for the maintenance of normal septation
NG825_04420	COG2207	Transcriptional regulator
NG825_04465	COG0393	Putative heavy-metal-binding
NG825_04485	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
NG825_04490	COG3791	Glutathione-dependent formaldehyde-activating
NG825_04500	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NG825_04505	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NG825_04515	COG0697	spore germination
NG825_04550	COG0804	urea catabolic process
NG825_04555	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
NG825_04565	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
NG825_04570	COG0726	polysaccharide deacetylase
NG825_04585	COG0436	Aminotransferase
NG825_04590	COG1162	GTPase activity
NG825_04620	COG2211	Major facilitator Superfamily
NG825_04640	COG1028	Short-chain dehydrogenase reductase Sdr
NG825_04660	COG0642	Histidine kinase
NG825_04670	COG2205	protein histidine kinase activity
NG825_04670	COG3292	Two component regulator propeller
NG825_04670	COG0745	RESPONSE REGULATOR receiver
NG825_04670	COG2205	protein histidine kinase activity
NG825_04670	COG3292	Two component regulator propeller
NG825_04670	COG0745	RESPONSE REGULATOR receiver
NG825_04695	COG1301	dicarboxylic acid transport
NG825_04700	COG0281	malic enzyme
NG825_04700	COG0280	phosphate acetyltransferase
NG825_04715	COG0438	transferase activity, transferring glycosyl groups
NG825_04730	COG1519	Transferase
NG825_04735	COG1538	Outer membrane efflux protein
NG825_04740	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
NG825_04765	COG0300	oxidoreductase activity
NG825_04795	COG3706	GGDEF domain
NG825_04800	COG0473	3-isopropylmalate dehydrogenase activity
NG825_04820	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NG825_04840	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NG825_04845	COG0405	Gamma-glutamyltransferase
NG825_04860	COG0840	transmembrane signaling receptor activity
NG825_04865	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
NG825_04875	COG4946	Tricorn protease homolog
NG825_04875	COG1506	peptidase
NG825_04875	COG0823	Involved in the tonB-independent uptake of proteins
NG825_04900	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
NG825_04910	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
NG825_04935	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
NG825_04950	COG0586	Pfam SNARE associated Golgi protein
NG825_04970	COG0346	lactoylglutathione lyase activity
NG825_04975	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NG825_04980	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NG825_04990	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
NG825_04995	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
NG825_05000	COG0352	thiamine-phosphate diphosphorylase activity
NG825_05005	COG1773	rubredoxin
NG825_05020	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NG825_05030	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NG825_05060	COG3079	Belongs to the UPF0149 family
NG825_05065	COG0006	proline dipeptidase activity
NG825_05075	COG0006	proline dipeptidase activity
NG825_05100	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NG825_05110	COG0346	lactoylglutathione lyase activity
NG825_05115	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
NG825_05120	COG1561	YicC-like family, N-terminal region
NG825_05125	COG0194	GDP metabolic process
NG825_05130	COG1758	RNA polymerase activity
NG825_05135	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NG825_05145	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NG825_05155	COG0254	rRNA binding
NG825_05170	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
NG825_05200	COG0714	Associated with various cellular activities
NG825_05240	COG1301	dicarboxylic acid transport
NG825_05245	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NG825_05310	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
NG825_05315	COG4149	molybdate abc transporter
NG825_05330	COG0640	Transcriptional regulator
NG825_05345	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NG825_05370	COG3047	cAMP biosynthetic process
NG825_05375	COG3047	cAMP biosynthetic process
NG825_05380	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NG825_05420	COG0469	pyruvate kinase activity
NG825_05430	COG3588	fructose-bisphosphate aldolase
NG825_05440	COG2205	protein histidine kinase activity
NG825_05455	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
NG825_05490	COG0583	DNA-binding transcription factor activity
NG825_05500	COG5002	protein histidine kinase activity
NG825_05505	COG1393	Belongs to the ArsC family
NG825_05525	COG0175	sulfate reduction
NG825_05530	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NG825_05535	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NG825_05540	COG0175	sulfate reduction
NG825_05545	COG0529	Catalyzes the synthesis of activated sulfate
NG825_05545	COG2895	sulfate adenylyltransferase (ATP) activity
NG825_05560	COG0308	aminopeptidase N
NG825_05570	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NG825_05575	COG0438	transferase activity, transferring glycosyl groups
NG825_05595	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NG825_05610	COG1609	Transcriptional regulator
NG825_05625	COG0179	Fumarylacetoacetate (FAA) hydrolase
NG825_05640	COG3273	potassium ion transport
NG825_05640	COG0471	metal ion transport
NG825_05670	COG3511	phospholipase C
NG825_05680	COG0189	ligase activity
NG825_05685	COG0745	RESPONSE REGULATOR receiver
NG825_05700	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
NG825_05725	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NG825_05745	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
NG825_05755	COG4122	O-methyltransferase activity
NG825_05780	COG4221	oxidoreductase activity
NG825_05780	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NG825_05780	COG0300	oxidoreductase activity
NG825_05780	COG3321	synthase
NG825_05795	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NG825_05795	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NG825_05795	COG1028	Short-chain dehydrogenase reductase Sdr
NG825_05795	COG3321	synthase
NG825_05795	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NG825_05800	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NG825_05800	COG1028	Short-chain dehydrogenase reductase Sdr
NG825_05800	COG3321	synthase
NG825_05800	COG4221	oxidoreductase activity
NG825_05805	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NG825_05805	COG1028	Short-chain dehydrogenase reductase Sdr
NG825_05805	COG3321	synthase
NG825_05805	COG4221	oxidoreductase activity
NG825_05815	COG2267	carboxylic ester hydrolase activity
NG825_05825	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
NG825_05830	COG0726	polysaccharide deacetylase
NG825_05840	COG0667	Aldo Keto reductase
NG825_05875	COG2192	nodulation
NG825_05890	COG2226	methyltransferase
NG825_05895	COG1132	(ABC) transporter
NG825_05905	COG1028	Short-chain dehydrogenase reductase Sdr
NG825_05910	COG4993	Dehydrogenase
NG825_05920	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
NG825_05920	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NG825_05930	COG1262	PFAM Formylglycine-generating sulfatase enzyme
NG825_05945	COG1125	glycine betaine transport
NG825_05955	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NG825_05960	COG0564	pseudouridine synthase activity
NG825_05985	COG0840	transmembrane signaling receptor activity
NG825_06015	COG0454	-acetyltransferase
NG825_06040	COG0542	response to heat
NG825_06065	COG2223	nitrite transmembrane transporter activity
NG825_06080	COG0019	diaminopimelate decarboxylase activity
NG825_06085	COG4264	IucA IucC family
NG825_06090	COG2814	Major facilitator Superfamily
NG825_06095	COG4264	IucA IucC family
NG825_06105	COG4772	TonB-dependent receptor
NG825_06115	COG4651	solute:proton antiporter activity
NG825_06115	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NG825_06150	COG0488	(ABC) transporter
NG825_06170	COG0657	acetylesterase activity
NG825_06170	COG2755	lipolytic protein G-D-S-L family
NG825_06195	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NG825_06235	COG0632	four-way junction helicase activity
NG825_06240	COG3158	transport of potassium into the cell
NG825_06245	COG2255	four-way junction helicase activity
NG825_06250	COG0824	Thioesterase
NG825_06260	COG0848	biopolymer transport protein
NG825_06275	COG2885	chlorophyll binding
NG825_06285	COG0602	queuosine metabolic process
NG825_06290	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NG825_06325	COG0514	ATP-dependent DNA helicase (RecQ)
NG825_06330	COG0783	Belongs to the Dps family
NG825_06335	COG1643	Atp-dependent helicase
NG825_06355	COG0535	radical SAM domain protein
NG825_06375	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NG825_06385	COG1216	Glycosyl transferase, family 2
NG825_06390	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NG825_06400	COG1199	ATP-dependent helicase activity
NG825_06425	COG0189	ligase activity
NG825_06440	COG0835	chemotaxis
NG825_06445	COG0840	transmembrane signaling receptor activity
NG825_06455	COG2201	protein-glutamate methylesterase activity
NG825_06465	COG3209	COG3209 Rhs family protein
NG825_06475	COG1446	asparaginase
NG825_06520	COG1733	regulation of RNA biosynthetic process
NG825_06525	COG0604	alcohol dehydrogenase
NG825_06585	COG3537	Alpha-1,2-mannosidase
NG825_06595	COG1486	melibiose metabolic process
NG825_06605	COG0531	amino acid
NG825_06620	COG1472	Belongs to the glycosyl hydrolase 3 family
NG825_06630	COG3525	Glycosyl hydrolase, family 20, catalytic domain
NG825_06635	COG1388	LysM domain
NG825_06635	COG3858	chitin binding
NG825_06650	COG0837	glucose binding
NG825_06655	COG1385	rRNA (uridine-N3-)-methyltransferase activity
NG825_06665	COG0494	nUDIX hydrolase
NG825_06670	COG1218	3'(2'),5'-bisphosphate nucleotidase
NG825_06675	COG3956	TIGRFAM MazG family protein
NG825_06690	COG0330	HflC and HflK could
NG825_06745	COG1960	acyl-CoA dehydrogenase activity
NG825_06755	COG1309	transcriptional regulator
NG825_06770	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NG825_06775	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NG825_06780	COG0463	Glycosyl transferase, family 2
NG825_06785	COG0517	IMP dehydrogenase activity
NG825_06795	COG1272	protein, Hemolysin III
NG825_06800	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NG825_06810	COG1131	(ABC) transporter
NG825_06815	COG1725	Transcriptional regulator
NG825_06820	COG0739	heme binding
NG825_06825	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NG825_06830	COG0626	cystathionine gamma-synthase activity
NG825_06835	COG0527	aspartate kinase activity
NG825_06835	COG0460	homoserine dehydrogenase
NG825_06850	COG2267	carboxylic ester hydrolase activity
NG825_06855	COG3706	GGDEF domain
NG825_06860	COG1760	l-serine dehydratase
NG825_06875	COG3038	cytochrome b561
NG825_06880	COG2353	YceI-like domain
NG825_06885	COG5002	protein histidine kinase activity
NG825_06885	COG0784	Response regulator, receiver
NG825_06895	COG0477	Major facilitator Superfamily
NG825_06900	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
NG825_06910	COG1609	Transcriptional regulator
NG825_06910	COG2207	Transcriptional regulator
NG825_06915	COG1335	isochorismatase
NG825_06925	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NG825_06945	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NG825_06960	COG0477	Major facilitator Superfamily
NG825_06985	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NG825_07050	COG0519	Catalyzes the synthesis of GMP from XMP
NG825_07060	COG1678	Uncharacterized ACR, COG1678
NG825_07065	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NG825_07085	COG0840	transmembrane signaling receptor activity
NG825_07090	COG0840	transmembrane signaling receptor activity
NG825_07105	COG1113	amino acid transport
NG825_07130	COG2239	Acts as a magnesium transporter
NG825_07135	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NG825_07140	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NG825_07150	COG1660	Displays ATPase and GTPase activities
NG825_07160	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NG825_07180	COG1137	ATPase activity
NG825_07195	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
NG825_07255	COG0628	permease
NG825_07265	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
NG825_07270	COG3178	'Phosphotransferase
NG825_07300	COG1477	protein flavinylation
NG825_07405	COG1981	membrane
NG825_07440	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NG825_07445	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NG825_07450	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NG825_07460	COG0750	zinc metalloprotease
NG825_07465	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
NG825_07470	COG0575	Belongs to the CDS family
NG825_07475	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NG825_07535	COG0024	Methionine aminopeptidase
NG825_07560	COG1393	Belongs to the ArsC family
NG825_07570	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NG825_07575	COG0367	asparagine synthase
NG825_07635	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
NG825_07675	COG1846	Transcriptional regulator
NG825_07685	COG1566	PFAM secretion protein HlyD family protein
NG825_07690	COG2814	Major facilitator Superfamily
NG825_07730	COG0557	exoribonuclease II activity
NG825_07740	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NG825_07760	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NG825_07780	COG0704	Plays a role in the regulation of phosphate uptake
NG825_07790	COG0581	inorganic phosphate transmembrane transporter activity
NG825_07795	COG0573	inorganic phosphate transmembrane transporter activity
NG825_07800	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
NG825_07805	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
NG825_07815	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NG825_07825	COG1024	Enoyl-CoA hydratase
NG825_07870	COG0488	(ABC) transporter
NG825_07875	COG0116	Belongs to the methyltransferase superfamily
NG825_07875	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
NG825_07885	COG2205	protein histidine kinase activity
NG825_07885	COG3437	response regulator, receiver
NG825_07885	COG3850	Histidine kinase
NG825_07885	COG4999	Histidine kinase
NG825_07890	COG2733	membrane
NG825_07910	COG0686	Belongs to the AlaDH PNT family
NG825_07915	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NG825_07920	COG1917	Cupin 2, conserved barrel domain protein
NG825_07920	COG1396	sequence-specific DNA binding
NG825_07925	COG1012	belongs to the aldehyde dehydrogenase family
NG825_07945	COG0243	molybdopterin cofactor binding
NG825_07965	COG0477	Major facilitator Superfamily
NG825_07975	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NG825_07985	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
NG825_08020	COG3842	ATPase activity
NG825_08025	COG1176	ABC-type spermidine putrescine transport system, permease component I
NG825_08030	COG1177	transmembrane transport
NG825_08035	COG1012	belongs to the aldehyde dehydrogenase family
NG825_08050	COG4535	Mg2 and Co2 transporter CorC
NG825_08060	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NG825_08075	COG1702	phosphate starvation-inducible protein PhoH
NG825_08100	COG0741	lytic transglycosylase activity
NG825_08105	COG0723	plastoquinol--plastocyanin reductase activity
NG825_08110	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
NG825_08115	COG2857	Cytochrome c1
NG825_08120	COG0625	glutathione transferase activity
NG825_08125	COG2969	positive regulation of protein catabolic process
NG825_08165	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
NG825_08170	COG1028	Short-chain dehydrogenase reductase Sdr
NG825_08175	COG2095	MarC family integral membrane protein
NG825_08185	COG1611	Belongs to the LOG family
NG825_08190	COG3275	phosphorelay sensor kinase activity
NG825_08235	COG0556	nucleotide-excision repair
NG825_08250	COG3505	Type IV secretory pathway VirD4
NG825_08320	COG0366	Alpha amylase catalytic
NG825_08330	COG1082	Xylose isomerase domain protein TIM barrel
NG825_08360	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NG825_08370	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NG825_08375	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NG825_08380	COG0072	phenylalanine-tRNA ligase activity
NG825_08380	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NG825_08425	COG0438	transferase activity, transferring glycosyl groups
NG825_08430	COG0438	transferase activity, transferring glycosyl groups
NG825_08440	COG0438	transferase activity, transferring glycosyl groups
NG825_08465	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NG825_08475	COG1960	acyl-CoA dehydrogenase activity
NG825_08480	COG2197	response regulator
NG825_08490	COG2815	serine threonine protein kinase
NG825_08490	COG0515	serine threonine protein kinase
NG825_08505	COG1404	Belongs to the peptidase S8 family
NG825_08510	COG1404	Belongs to the peptidase S8 family
NG825_08530	COG1846	Transcriptional regulator
NG825_08550	COG3040	lipid binding
NG825_08560	COG1570	exodeoxyribonuclease VII activity
NG825_08565	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NG825_08570	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NG825_08570	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
NG825_08575	COG0802	atpase or kinase
NG825_08580	COG0860	N-Acetylmuramoyl-L-alanine amidase
NG825_08605	COG1028	Short-chain dehydrogenase reductase Sdr
NG825_08625	COG2081	HI0933 family
NG825_08630	COG4681	YaeQ
NG825_08640	COG0625	glutathione transferase activity
NG825_08680	COG0513	Belongs to the DEAD box helicase family
NG825_08685	COG0488	(ABC) transporter
NG825_08700	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NG825_08710	COG1472	Belongs to the glycosyl hydrolase 3 family
NG825_08790	COG3209	COG3209 Rhs family protein
NG825_08850	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
NG825_08860	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
NG825_08865	COG0671	phosphoesterase, PA-phosphatase related
NG825_08875	COG1794	racemase activity, acting on amino acids and derivatives
NG825_08885	COG0812	UDP-N-acetylmuramate dehydrogenase activity
NG825_08890	COG0167	dihydroorotate dehydrogenase activity
NG825_08905	COG1012	belongs to the aldehyde dehydrogenase family
NG825_08925	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NG825_08935	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NG825_08950	COG0124	histidyl-tRNA synthetase
NG825_08965	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
NG825_08985	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NG825_09000	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NG825_09000	COG0140	phosphoribosyl-ATP diphosphatase activity
NG825_09015	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
NG825_09020	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
NG825_09030	COG0531	amino acid
NG825_09035	COG0531	amino acid
NG825_09045	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NG825_09050	COG0277	FAD linked oxidase domain protein
NG825_09070	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NG825_09090	COG1024	Enoyl-CoA hydratase
NG825_09110	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NG825_09115	COG2258	MOSC domain
NG825_09125	COG0505	Belongs to the CarA family
NG825_09140	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NG825_09170	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
NG825_09180	COG0784	Response regulator, receiver
NG825_09180	COG2198	Histidine kinase
NG825_09180	COG2205	protein histidine kinase activity
NG825_09185	COG1024	Enoyl-CoA hydratase
NG825_09190	COG0318	PFAM AMP-dependent synthetase and ligase
NG825_09195	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
NG825_09200	COG1012	belongs to the aldehyde dehydrogenase family
NG825_09205	COG1309	transcriptional regulator
NG825_09210	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
NG825_09240	COG2201	protein-glutamate methylesterase activity
NG825_09255	COG0840	transmembrane signaling receptor activity
NG825_09260	COG0840	transmembrane signaling receptor activity
NG825_09265	COG0840	transmembrane signaling receptor activity
NG825_09275	COG0835	chemotaxis
NG825_09285	COG0840	transmembrane signaling receptor activity
NG825_09300	COG0840	transmembrane signaling receptor activity
NG825_09305	COG0840	transmembrane signaling receptor activity
NG825_09310	COG0840	transmembrane signaling receptor activity
NG825_09320	COG0840	transmembrane signaling receptor activity
NG825_09325	COG0840	transmembrane signaling receptor activity
NG825_09330	COG0840	transmembrane signaling receptor activity
NG825_09335	COG0840	transmembrane signaling receptor activity
NG825_09340	COG0840	transmembrane signaling receptor activity
NG825_09345	COG0840	transmembrane signaling receptor activity
NG825_09355	COG0745	RESPONSE REGULATOR receiver
NG825_09365	COG0835	chemotaxis
NG825_09370	COG1192	Involved in chromosome partitioning
NG825_09375	COG1360	Flagellar Motor Protein
NG825_09380	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
NG825_09385	COG2198	Histidine kinase
NG825_09385	COG0784	Response regulator, receiver
NG825_09385	COG0643	Histidine kinase
NG825_09390	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
NG825_09445	COG3190	flagellar
NG825_09485	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NG825_09495	COG1677	Flagellar hook-basal body complex protein FliE
NG825_09540	COG1028	Short-chain dehydrogenase reductase Sdr
NG825_09545	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NG825_09565	COG2201	protein-glutamate methylesterase activity
NG825_09575	COG2197	response regulator
NG825_09600	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NG825_09605	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NG825_09610	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NG825_09630	COG1706	bacterial-type flagellum-dependent cell motility
NG825_09635	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
NG825_09645	COG4787	bacterial-type flagellum-dependent cell motility
NG825_09655	COG1749	Flagellar hook protein flgE
NG825_09665	COG1558	bacterial-type flagellum-dependent cell motility
NG825_09675	COG0784	Response regulator, receiver
NG825_09675	COG0835	chemotaxis
NG825_09695	COG4191	Histidine kinase
NG825_09720	COG1116	anion transmembrane transporter activity
NG825_09735	COG2915	High frequency lysogenization protein hflD homolog
NG825_09740	COG0482	sulfurtransferase activity
NG825_09760	COG0542	response to heat
NG825_09785	COG0492	ferredoxin-NADP+ reductase activity
NG825_09790	COG1674	ftsk spoiiie
NG825_09805	COG1230	cation diffusion facilitator family transporter
NG825_09810	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
NG825_09815	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NG825_09850	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NG825_09885	COG1595	DNA-templated transcription, initiation
NG825_09935	COG2244	polysaccharide biosynthetic process
NG825_09940	COG1215	transferase activity, transferring glycosyl groups
NG825_09960	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
NG825_09975	COG0438	transferase activity, transferring glycosyl groups
NG825_09980	COG0438	transferase activity, transferring glycosyl groups
NG825_10000	COG1132	(ABC) transporter
NG825_10035	COG1136	(ABC) transporter
NG825_10060	COG0583	DNA-binding transcription factor activity
NG825_10070	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NG825_10080	COG3552	Protein containing von Willebrand factor type A (VWA) domain
NG825_10090	COG0714	Associated with various cellular activities
NG825_10185	COG2205	protein histidine kinase activity
NG825_10185	COG0784	Response regulator, receiver
NG825_10195	COG0784	Response regulator, receiver
NG825_10195	COG4191	Histidine kinase
NG825_10205	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
NG825_10205	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NG825_10215	COG1983	PspC domain protein
NG825_10225	COG3243	poly(R)-hydroxyalkanoic acid synthase
NG825_10235	COG1183	phosphatidylcholine synthase activity
NG825_10240	COG1028	Short-chain dehydrogenase reductase Sdr
NG825_10280	COG0668	transmembrane transport
NG825_10285	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
NG825_10295	COG1321	iron dependent repressor
NG825_10300	COG1914	H( )-stimulated, divalent metal cation uptake system
NG825_10340	COG5002	protein histidine kinase activity
NG825_10360	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NG825_10365	COG3002	Belongs to the UPF0753 family
NG825_10370	COG1733	regulation of RNA biosynthetic process
NG825_10375	COG1247	-acetyltransferase
NG825_10390	COG0431	NADPH-dependent FMN reductase
NG825_10400	COG0519	Catalyzes the synthesis of GMP from XMP
NG825_10400	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NG825_10410	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NG825_10420	COG1073	alpha beta
NG825_10425	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NG825_10425	COG0475	glutathione-regulated potassium exporter activity
NG825_10430	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NG825_10445	COG1160	GTP binding
NG825_10450	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NG825_10455	COG2976	Protein conserved in bacteria
NG825_10460	COG1426	Protein conserved in bacteria
NG825_10470	COG0820	rRNA (adenine-C2-)-methyltransferase activity
NG825_10490	COG0183	Belongs to the thiolase family
NG825_10495	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NG825_10510	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
NG825_10520	COG0776	regulation of translation
NG825_10530	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
NG825_10535	COG0257	Belongs to the bacterial ribosomal protein bL36 family
NG825_10545	COG2957	Belongs to the agmatine deiminase family
NG825_10550	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NG825_10560	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NG825_10570	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NG825_10595	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
NG825_10595	COG0316	Belongs to the HesB IscA family
NG825_10610	COG0428	transporter
NG825_10615	COG3064	Membrane
NG825_10625	COG1530	ribonuclease E activity
NG825_10705	COG0583	DNA-binding transcription factor activity
NG825_10735	COG0077	Prephenate dehydratase
NG825_10735	COG1605	Chorismate mutase
NG825_10740	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NG825_10745	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
NG825_10750	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
NG825_10785	COG4221	oxidoreductase activity
NG825_10800	COG1228	amidohydrolase
NG825_10860	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
NG825_10880	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NG825_10885	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NG825_10900	COG0359	binds to the 23S rRNA
NG825_10905	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NG825_10915	COG0316	Belongs to the HesB IscA family
NG825_10940	COG2197	response regulator
NG825_10985	COG0288	reversible hydration of carbon dioxide
NG825_11000	COG3844	kynureninase activity
NG825_11010	COG2925	Exonuclease
NG825_11055	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NG825_11060	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NG825_11065	COG1960	acyl-CoA dehydrogenase activity
NG825_11070	COG2226	methyltransferase
NG825_11080	COG1410	methionine synthase
NG825_11080	COG0646	methionine synthase
NG825_11095	COG2755	lipolytic protein G-D-S-L family
NG825_11095	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
NG825_11105	COG2900	Belongs to the SlyX family
NG825_11120	COG0386	Belongs to the glutathione peroxidase family
NG825_11130	COG1725	Transcriptional regulator
NG825_11135	COG1131	(ABC) transporter
NG825_11155	COG0697	spore germination
NG825_11160	COG0436	Aminotransferase
NG825_11180	COG1253	flavin adenine dinucleotide binding
NG825_11195	COG2850	peptidyl-arginine hydroxylation
NG825_11245	COG1132	(ABC) transporter
NG825_11260	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
NG825_11265	COG0484	heat shock protein binding
NG825_11270	COG0443	Heat shock 70 kDa protein
NG825_11275	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NG825_11280	COG1420	regulation of RNA biosynthetic process
NG825_11285	COG0497	DNA recombination
NG825_11290	COG0735	belongs to the Fur family
NG825_11295	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NG825_11310	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
NG825_11355	COG3706	GGDEF domain
NG825_11390	COG0583	DNA-binding transcription factor activity
NG825_11395	COG2885	chlorophyll binding
NG825_11395	COG3047	cAMP biosynthetic process
NG825_11405	COG0415	Belongs to the DNA photolyase family
NG825_11415	COG0305	Participates in initiation and elongation during chromosome replication
NG825_11435	COG1960	acyl-CoA dehydrogenase activity
NG825_11450	COG0084	hydrolase, TatD family'
NG825_11455	COG2203	Gaf domain
NG825_11455	COG4251	negative regulation of phosphorylation
NG825_11455	COG5001	Diguanylate cyclase
NG825_11455	COG3706	GGDEF domain
NG825_11460	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
NG825_11515	COG1595	DNA-templated transcription, initiation
NG825_11520	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NG825_11550	COG0386	Belongs to the glutathione peroxidase family
NG825_11555	COG0339	signal peptide processing
NG825_11610	COG0166	Belongs to the GPI family
NG825_11625	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
NG825_11630	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NG825_11635	COG0617	tRNA 3'-terminal CCA addition
NG825_11650	COG0477	Major facilitator Superfamily
NG825_11655	COG2115	Belongs to the xylose isomerase family
NG825_11660	COG1070	Carbohydrate kinase
NG825_11665	COG1501	Belongs to the glycosyl hydrolase 31 family
NG825_11690	COG0800	Aldolase
NG825_11705	COG3734	2-keto-3-deoxy-galactonokinase
NG825_11710	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
NG825_11720	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NG825_11730	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NG825_11735	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
NG825_11750	COG0352	thiamine-phosphate diphosphorylase activity
NG825_11750	COG0351	phosphomethylpyrimidine kinase
NG825_11770	COG1028	Short-chain dehydrogenase reductase Sdr
NG825_11785	COG0583	DNA-binding transcription factor activity
NG825_11790	COG1741	Belongs to the pirin family
NG825_11840	COG0583	DNA-binding transcription factor activity
NG825_11875	COG2003	Belongs to the UPF0758 family
NG825_11980	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
NG825_11985	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NG825_11990	COG2137	regulation of response to DNA damage stimulus
NG825_11995	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NG825_12000	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NG825_12005	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
NG825_12010	COG1546	Belongs to the CinA family
NG825_12015	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NG825_12030	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NG825_12035	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NG825_12040	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
NG825_12045	COG1534	Rna-binding protein
NG825_12075	COG2840	Smr protein MutS2
NG825_12085	COG1595	DNA-templated transcription, initiation
NG825_12110	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
NG825_12120	COG0148	phosphopyruvate hydratase activity
NG825_12130	COG2877	3-deoxy-8-phosphooctulonate synthase activity
NG825_12155	COG2134	cdp-diacylglycerol pyrophosphatase
NG825_12165	COG0306	phosphate transporter
NG825_12175	COG1253	flavin adenine dinucleotide binding
NG825_12190	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NG825_12235	COG0456	acetyltransferase
NG825_12245	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
NG825_12260	COG1609	Transcriptional regulator
NG825_12265	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
NG825_12265	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NG825_12270	COG1105	Belongs to the carbohydrate kinase PfkB family
NG825_12275	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NG825_12275	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NG825_12305	COG0577	efflux transmembrane transporter activity
NG825_12305	COG1136	(ABC) transporter
NG825_12345	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NG825_12355	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NG825_12360	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
NG825_12365	COG0583	DNA-binding transcription factor activity
NG825_12495	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NG825_12520	COG1663	tetraacyldisaccharide 4'-kinase activity
NG825_12530	COG0848	biopolymer transport protein
NG825_12535	COG0811	peptide transport
NG825_12540	COG2333	competence protein COMEC
NG825_12540	COG0658	competence protein
NG825_12550	COG1136	(ABC) transporter
NG825_12555	COG4591	ABC-type transport system involved in lipoprotein release permease component
NG825_12580	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
NG825_12585	COG2009	succinate dehydrogenase
NG825_12595	COG0354	folic acid binding
NG825_12600	COG3842	ATPase activity
NG825_12605	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NG825_12620	COG0129	dihydroxy-acid dehydratase activity
NG825_12625	COG0800	Aldolase
NG825_12635	COG0395	ABC-type sugar transport system, permease component
NG825_12645	COG2182	Extracellular solute-binding protein
NG825_12670	COG2350	Protein conserved in bacteria
NG825_12675	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NG825_12680	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NG825_12685	COG1187	pseudouridine synthase activity
NG825_12735	COG0436	Aminotransferase
NG825_12740	COG4133	protoheme IX ABC transporter activity
NG825_12785	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NG825_12795	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
NG825_12800	COG4988	ABC transporter
NG825_12810	COG1294	oxidase, subunit
NG825_12855	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NG825_12870	COG0165	Argininosuccinate lyase
NG825_12885	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
NG825_12890	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NG825_12900	COG0137	argininosuccinate synthase activity
NG825_12905	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NG825_12920	COG2166	iron-sulfur cluster assembly
NG825_12955	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NG825_12990	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
NG825_13005	COG3706	GGDEF domain
NG825_13010	COG4677	pectinesterase activity
NG825_13035	COG3548	integral membrane protein
NG825_13045	COG1509	lysine 2,3-aminomutase activity
NG825_13070	COG0840	transmembrane signaling receptor activity
NG825_13075	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NG825_13085	COG1862	Preprotein translocase
NG825_13095	COG1132	(ABC) transporter
NG825_13130	COG1187	pseudouridine synthase activity
NG825_13180	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NG825_13220	COG2080	2 iron, 2 sulfur cluster binding
NG825_13225	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
NG825_13230	COG1529	Aldehyde oxidase and xanthine dehydrogenase
NG825_13235	COG0746	molybdenum cofactor guanylyltransferase activity
NG825_13240	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
NG825_13245	COG3214	Protein conserved in bacteria
NG825_13250	COG0735	belongs to the Fur family
NG825_13275	COG4452	Inner membrane protein CreD
NG825_13280	COG2205	protein histidine kinase activity
NG825_13295	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
NG825_13300	COG3878	Protein conserved in bacteria
NG825_13320	COG2198	Histidine kinase
NG825_13320	COG0643	Histidine kinase
NG825_13325	COG0840	transmembrane signaling receptor activity
NG825_13330	COG3290	protein histidine kinase activity
NG825_13330	COG0840	transmembrane signaling receptor activity
NG825_13335	COG0840	transmembrane signaling receptor activity
NG825_13375	COG2977	Belongs to the P-Pant transferase superfamily
NG825_13385	COG0588	phosphoglycerate mutase activity
NG825_13395	COG1741	Belongs to the pirin family
NG825_13405	COG1741	Belongs to the pirin family
NG825_13410	COG1966	Carbon starvation protein
NG825_13415	COG2879	small protein
NG825_13445	COG0823	Involved in the tonB-independent uptake of proteins
NG825_13445	COG1506	peptidase
NG825_13450	COG1297	OPT oligopeptide transporter protein
NG825_13455	COG3104	oligopeptide transport
NG825_13475	COG1609	Transcriptional regulator
NG825_13485	COG2211	Major facilitator Superfamily
NG825_13490	COG0673	inositol 2-dehydrogenase activity
NG825_13500	COG2010	Cytochrome c
NG825_13550	COG0653	protein targeting
NG825_13565	COG0629	single-stranded DNA binding
NG825_13570	COG0142	geranyltranstransferase activity
NG825_13600	COG0527	aspartate kinase activity
NG825_13610	COG0384	phenazine biosynthesis protein PhzF
NG825_13620	COG1764	response to oxidative stress
NG825_13635	COG0739	heme binding
NG825_13650	COG0693	protein deglycase activity
NG825_13665	COG0719	Fe-S assembly protein
NG825_13670	COG0396	ATPase activity
NG825_13675	COG0719	Fe-S assembly protein
NG825_13680	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NG825_13690	COG2146	nitrite reductase [NAD(P)H] activity
NG825_13695	COG0840	transmembrane signaling receptor activity
NG825_13700	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NG825_13710	COG1538	Outer membrane efflux protein
NG825_13730	COG0642	Histidine kinase
NG825_13735	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NG825_13740	COG0405	Gamma-glutamyltransferase
NG825_13745	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
NG825_13760	COG0742	ribosomal rna small subunit methyltransferase
NG825_13765	COG0326	Molecular chaperone. Has ATPase activity
NG825_13795	COG3507	Belongs to the glycosyl hydrolase 43 family
NG825_13805	COG4206	TonB-dependent receptor
NG825_13830	COG0531	amino acid
NG825_13845	COG0006	proline dipeptidase activity
NG825_13855	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NG825_13870	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NG825_13875	COG3938	Belongs to the proline racemase family
NG825_13885	COG0552	protein localization to endoplasmic reticulum
NG825_13890	COG1194	a g-specific adenine glycosylase
NG825_13935	COG0835	chemotaxis
NG825_13940	COG3290	protein histidine kinase activity
NG825_13940	COG0840	transmembrane signaling receptor activity
NG825_13945	COG0840	transmembrane signaling receptor activity
NG825_13950	COG1201	RNA secondary structure unwinding
NG825_13960	COG3300	MHYT domain
NG825_13960	COG5001	Diguanylate cyclase
NG825_13965	COG1185	polyribonucleotide nucleotidyltransferase activity
NG825_13990	COG0195	Participates in both transcription termination and antitermination
NG825_14040	COG1034	ATP synthesis coupled electron transport
NG825_14050	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
NG825_14055	COG0649	NAD binding
NG825_14070	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NG825_14090	COG1028	Short-chain dehydrogenase reductase Sdr
NG825_14125	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NG825_14130	COG0159	tryptophan synthase activity
NG825_14135	COG0133	tryptophan synthase activity
NG825_14170	COG0135	phosphoribosylanthranilate isomerase activity
NG825_14175	COG0101	tRNA pseudouridine synthase activity
NG825_14185	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NG825_14195	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NG825_14200	COG2890	protein-(glutamine-N5) methyltransferase activity
NG825_14215	COG0741	lytic transglycosylase activity
NG825_14220	COG0433	COG0433 Predicted ATPase
NG825_14230	COG0494	nUDIX hydrolase
NG825_14245	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NG825_14270	COG1714	RDD family
NG825_14275	COG0717	Belongs to the dCTP deaminase family
NG825_14280	COG0489	protein tyrosine kinase activity
NG825_14285	COG4771	TonB-dependent receptor
NG825_14295	COG0457	Tetratricopeptide repeat
NG825_14310	COG4206	TonB-dependent receptor
NG825_14325	COG3590	peptidase
NG825_14355	COG2311	Membrane
NG825_14365	COG0791	NLP P60 protein
NG825_14370	COG0791	NLP P60 protein
NG825_14375	COG2226	methyltransferase
NG825_14400	COG1607	acyl-coa hydrolase
NG825_14405	COG2226	methyltransferase
NG825_14410	COG1301	dicarboxylic acid transport
NG825_14415	COG1785	Belongs to the alkaline phosphatase family
NG825_14425	COG0037	tRNA processing
NG825_14430	COG1722	exodeoxyribonuclease VII activity
NG825_14435	COG0142	geranyltranstransferase activity
NG825_14440	COG4104	PAAR repeat-containing protein
NG825_14465	COG0312	modulator of DNA gyrase
NG825_14475	COG0312	modulator of DNA gyrase
NG825_14495	COG2968	Membrane
NG825_14510	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NG825_14525	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NG825_14540	COG0495	leucyl-tRNA aminoacylation
NG825_14550	COG3118	belongs to the thioredoxin family
NG825_14575	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
NG825_14585	COG2040	homocysteine
NG825_14595	COG0346	lactoylglutathione lyase activity
NG825_14605	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NG825_14605	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NG825_14615	COG2878	Part of a membrane complex involved in electron transport
NG825_14630	COG1595	DNA-templated transcription, initiation
NG825_14655	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
NG825_14675	COG0251	oxidation-reduction process
NG825_14685	COG0392	lysyltransferase activity
NG825_14720	COG2814	Major facilitator Superfamily
NG825_14725	COG1902	pentaerythritol trinitrate reductase activity
NG825_14730	COG2824	Alkylphosphonate utilization operon protein PhnA
NG825_14740	COG1047	Peptidyl-prolyl cis-trans
NG825_14745	COG1077	Cell shape determining protein MreB Mrl
NG825_14770	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
NG825_14780	COG1451	nucleotide metabolic process
NG825_14785	COG1187	pseudouridine synthase activity
NG825_14795	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NG825_14800	COG4771	TonB-dependent receptor
NG825_14815	COG5487	UPF0391 membrane protein
NG825_14850	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
NG825_14850	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
NG825_14850	COG1703	isobutyryl-CoA mutase activity
NG825_14870	COG0183	Belongs to the thiolase family
NG825_14900	COG1960	acyl-CoA dehydrogenase activity
NG825_14905	COG1793	dna ligase
NG825_14905	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
NG825_14910	COG1793	dna ligase
NG825_14910	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
NG825_14915	COG1201	RNA secondary structure unwinding
NG825_14925	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NG825_14930	COG1278	Cold shock
NG825_14940	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
NG825_14945	COG1472	Belongs to the glycosyl hydrolase 3 family
NG825_14955	COG2954	triphosphatase activity
NG825_14980	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NG825_14995	COG0681	Belongs to the peptidase S26 family
NG825_15000	COG0481	GTPase activity
NG825_15005	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NG825_15020	COG1024	Enoyl-CoA hydratase
NG825_15020	COG1250	3-hydroxyacyl-CoA dehydrogenase
NG825_15035	COG2855	membrane
NG825_15055	COG3250	beta-galactosidase activity
NG825_15065	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NG825_15080	COG0542	response to heat
NG825_15095	COG0534	Mate efflux family protein
NG825_15100	COG0335	large ribosomal subunit rRNA binding
NG825_15110	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NG825_15135	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NG825_15140	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NG825_15160	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NG825_15170	COG0475	glutathione-regulated potassium exporter activity
NG825_15180	COG0625	glutathione transferase activity
NG825_15185	COG1172	Belongs to the binding-protein-dependent transport system permease family
NG825_15190	COG1172	Belongs to the binding-protein-dependent transport system permease family
NG825_15195	COG1129	ABC transporter
NG825_15200	COG1879	ABC-type sugar transport system periplasmic component
NG825_15205	COG1012	belongs to the aldehyde dehydrogenase family
NG825_15225	COG0129	dihydroxy-acid dehydratase activity
NG825_15270	COG0740	serine-type endopeptidase activity
NG825_15275	COG1595	DNA-templated transcription, initiation
NG825_15280	COG1028	Short-chain dehydrogenase reductase Sdr
NG825_15290	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
NG825_15295	COG1845	cytochrome c oxidase, subunit III
NG825_15300	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NG825_15325	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NG825_15340	COG0196	riboflavin kinase activity
NG825_15355	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NG825_15360	COG0211	Belongs to the bacterial ribosomal protein bL27 family
NG825_15365	COG0261	This protein binds to 23S rRNA in the presence of protein L20
NG825_15370	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NG825_15375	COG0824	Thioesterase
NG825_15385	COG1024	Enoyl-CoA hydratase
NG825_15390	COG1946	Acyl-CoA thioesterase
NG825_15405	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
NG825_15420	COG0840	transmembrane signaling receptor activity
NG825_15440	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NG825_15445	COG4638	Rieske (2fe-2S)
NG825_15475	COG1073	alpha beta
NG825_15520	COG4585	Histidine kinase
NG825_15530	COG0850	regulation of cytokinetic process
NG825_15535	COG2894	cell division
NG825_15540	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
NG825_15550	COG2205	protein histidine kinase activity
NG825_15555	COG0745	RESPONSE REGULATOR receiver
NG825_15565	COG2194	sulfuric ester hydrolase activity
NG825_15595	COG0753	catalase activity
NG825_15600	COG1063	alcohol dehydrogenase
NG825_15685	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NG825_15740	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NG825_15750	COG0330	HflC and HflK could
NG825_15755	COG0330	HflC and HflK could
NG825_15760	COG0604	alcohol dehydrogenase
NG825_15780	COG0678	peroxiredoxin activity
NG825_15790	COG4953	penicillin-binding protein 1C
NG825_15815	COG0577	efflux transmembrane transporter activity
NG825_15815	COG1136	(ABC) transporter
NG825_15840	COG2373	Large extracellular alpha-helical protein
NG825_15895	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NG825_15925	COG2161	toxin-antitoxin pair type II binding
NG825_15930	COG4115	mRNA cleavage
NG825_15955	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NG825_15960	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NG825_15965	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NG825_15980	COG1028	Short-chain dehydrogenase reductase Sdr
NG825_15985	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
NG825_15990	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NG825_15995	COG0333	Belongs to the bacterial ribosomal protein bL32 family
NG825_16000	COG1399	metal-binding, possibly nucleic acid-binding protein
NG825_16025	COG0714	Associated with various cellular activities
NG825_16045	COG0537	adenosine 5'-monophosphoramidase activity
NG825_16060	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NG825_16075	COG0314	molybdopterin synthase activity
NG825_16080	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
NG825_16085	COG0315	cyclic pyranopterin monophosphate synthase activity
NG825_16095	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NG825_16100	COG1234	tRNA 3'-trailer cleavage
NG825_16105	COG3642	lipopolysaccharide core region biosynthetic process
NG825_16110	COG0859	PFAM glycosyl transferase family 9
NG825_16130	COG0631	protein serine/threonine phosphatase activity
NG825_16140	COG0328	RNA-DNA hybrid ribonuclease activity
NG825_16150	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NG825_16160	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NG825_16235	COG0473	3-isopropylmalate dehydrogenase activity
NG825_16250	COG4783	chaperone-mediated protein folding
NG825_16255	COG0745	RESPONSE REGULATOR receiver
NG825_16265	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
NG825_16270	COG0248	Ppx GppA phosphatase
NG825_16275	COG0438	transferase activity, transferring glycosyl groups
NG825_16280	COG0671	phosphoesterase, PA-phosphatase related
NG825_16290	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NG825_16300	COG3291	Pkd domain containing protein
NG825_16305	COG2833	Protein of unknown function (DUF455)
NG825_16330	COG0285	dihydrofolate synthase activity
NG825_16335	COG0588	phosphoglycerate mutase activity
NG825_16355	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
NG825_16360	COG4208	sulfate ABC transporter
NG825_16405	COG0583	DNA-binding transcription factor activity
NG825_16410	COG2814	Major facilitator Superfamily
NG825_16420	COG0667	Aldo Keto reductase
NG825_16425	COG0604	alcohol dehydrogenase
NG825_16430	COG1902	pentaerythritol trinitrate reductase activity
NG825_16430	COG0446	pyridine nucleotide-disulphide oxidoreductase
NG825_16450	COG0584	glycerophosphoryl diester phosphodiesterase
NG825_16470	COG0625	glutathione transferase activity
NG825_16490	COG0625	glutathione transferase activity
NG825_16510	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NG825_16515	COG1217	gtp-binding protein TYPA
NG825_16530	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
NG825_16540	COG1073	alpha beta
NG825_16550	COG0203	ribosomal protein L17
NG825_16560	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NG825_16570	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NG825_16575	COG0201	protein transport
NG825_16585	COG1841	ribosomal large subunit assembly
NG825_16595	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NG825_16610	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NG825_16615	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NG825_16620	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NG825_16630	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NG825_16635	COG0255	Belongs to the universal ribosomal protein uL29 family
NG825_16645	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NG825_16655	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NG825_16660	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NG825_16665	COG0089	rRNA binding
NG825_16670	COG0088	Forms part of the polypeptide exit tunnel
NG825_16680	COG0051	transcription antitermination factor activity, RNA binding
NG825_16685	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NG825_16690	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NG825_16695	COG0049	tRNA binding
NG825_16715	COG0222	ribosome binding
NG825_16720	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NG825_16735	COG0250	Participates in transcription elongation, termination and antitermination
NG825_16740	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
NG825_16750	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NG825_16770	COG0012	GTP binding
NG825_16775	COG0193	aminoacyl-tRNA hydrolase activity
NG825_16785	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NG825_16795	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NG825_16810	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
NG825_16815	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NG825_16840	COG0521	Mo-molybdopterin cofactor biosynthetic process
NG825_16855	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NG825_16880	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NG825_16885	COG1404	Belongs to the peptidase S8 family
NG825_16890	COG1404	Belongs to the peptidase S8 family
NG825_16895	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NG825_16955	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NG825_16955	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NG825_17000	COG2890	protein-(glutamine-N5) methyltransferase activity
NG825_17010	COG3634	alkyl hydroperoxide reductase activity
NG825_17015	COG0583	DNA-binding transcription factor activity
NG825_17020	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NG825_17040	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NG825_17050	COG2197	response regulator
NG825_17055	COG5002	protein histidine kinase activity
NG825_17055	COG0784	Response regulator, receiver
NG825_17055	COG2205	protein histidine kinase activity
NG825_17080	COG0697	spore germination
NG825_17135	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NG825_17140	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NG825_17150	COG2096	Adenosyltransferase
NG825_17165	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NG825_17170	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
NG825_17180	COG2967	ApaG domain
NG825_17185	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
NG825_17215	COG1704	LemA family
NG825_17220	COG0861	Integral membrane protein TerC family
NG825_17225	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
NG825_17235	COG0642	Histidine kinase
NG825_17250	COG4181	ATPase activity
NG825_17255	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
NG825_17270	COG4771	TonB-dependent receptor
NG825_17280	COG0667	Aldo Keto reductase
NG825_17285	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NG825_17300	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NG825_17305	COG4106	trans-aconitate 2-methyltransferase activity
NG825_17350	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NG825_17440	COG0840	transmembrane signaling receptor activity
NG825_17460	COG0366	Alpha amylase catalytic
NG825_17465	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
NG825_17475	COG0494	nUDIX hydrolase
NG825_17485	COG0653	protein targeting
NG825_17490	COG0739	heme binding
NG825_17515	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
NG825_17520	COG1181	Belongs to the D-alanine--D-alanine ligase family
NG825_17525	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
NG825_17560	COG3116	cell division
NG825_17605	COG1988	membrane-bound metal-dependent
NG825_17610	COG0277	FAD linked oxidase domain protein
NG825_17615	COG0745	RESPONSE REGULATOR receiver
NG825_17620	COG2205	protein histidine kinase activity
NG825_17630	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
NG825_17635	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
NG825_17655	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
NG825_17660	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NG825_17665	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
NG825_17680	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NG825_17680	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NG825_17690	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NG825_17710	COG0477	Major facilitator Superfamily
NG825_17720	COG0242	peptide deformylase activity
NG825_17735	COG1215	transferase activity, transferring glycosyl groups
NG825_17740	COG1215	transferase activity, transferring glycosyl groups
NG825_17755	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NG825_17800	COG2188	Transcriptional regulator
NG825_17820	COG1450	Type ii and iii secretion system protein
NG825_17835	COG3166	PFAM Fimbrial assembly family protein
NG825_17840	COG3156	type II secretion system protein K
NG825_17845	COG4795	General secretion pathway protein
NG825_17850	COG2165	general secretion pathway protein
NG825_17855	COG4970	Tfp pilus assembly protein FimT
NG825_17860	COG2165	general secretion pathway protein
NG825_17865	COG1459	type II secretion system
NG825_17870	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NG825_17875	COG1404	Belongs to the peptidase S8 family
NG825_17880	COG5295	Hep Hag repeat protein
NG825_17895	COG0047	phosphoribosylformylglycinamidine synthase activity
NG825_17895	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NG825_17900	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NG825_17910	COG4974	Belongs to the 'phage' integrase family
NG825_17935	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NG825_17965	COG1183	phosphatidylcholine synthase activity
NG825_17975	COG0442	prolyl-tRNA aminoacylation
NG825_17990	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
NG825_17995	COG1127	ABC transporter
NG825_18000	COG3218	ABC-type transport auxiliary lipoprotein component
NG825_18000	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
NG825_18035	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NG825_18040	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
NG825_18040	COG0662	Cupin 2, conserved barrel domain protein
NG825_18065	COG2086	electron transfer activity
NG825_18075	COG0546	phosphoglycolate phosphatase activity
NG825_18075	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
NG825_18080	COG0277	FAD linked oxidase domain protein
NG825_18085	COG0300	oxidoreductase activity
NG825_18100	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NG825_18105	COG1216	Glycosyl transferase, family 2
NG825_18105	COG1442	glycosyl transferase family 8
NG825_18160	COG0625	glutathione transferase activity
NG825_18170	COG0513	Belongs to the DEAD box helicase family
NG825_18175	COG0720	synthase
NG825_18185	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
NG825_18190	COG1956	GAF domain-containing protein
NG825_18200	COG4206	TonB-dependent receptor
NG825_18205	COG0546	phosphoglycolate phosphatase activity
NG825_18210	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NG825_18215	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NG825_18230	COG0339	signal peptide processing
NG825_18245	COG2217	Heavy metal translocating P-type atpase
NG825_18260	COG2132	Multicopper oxidase
NG825_18280	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
NG825_18290	COG1136	(ABC) transporter
NG825_18305	COG1136	(ABC) transporter
NG825_18305	COG0577	efflux transmembrane transporter activity
NG825_18315	COG0577	efflux transmembrane transporter activity
NG825_18320	COG1136	(ABC) transporter
NG825_18320	COG0577	efflux transmembrane transporter activity
NG825_18325	COG1136	(ABC) transporter
NG825_18325	COG0577	efflux transmembrane transporter activity
NG825_18335	COG0577	efflux transmembrane transporter activity
NG825_18340	COG1136	(ABC) transporter
NG825_18340	COG0577	efflux transmembrane transporter activity
NG825_18355	COG4191	Histidine kinase
NG825_18365	COG0456	acetyltransferase
NG825_18385	COG0355	proton-transporting ATP synthase activity, rotational mechanism
NG825_18390	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NG825_18400	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NG825_18410	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NG825_18420	COG0356	it plays a direct role in the translocation of protons across the membrane
NG825_18440	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NG825_18445	COG0508	dehydrogenase complex catalyzes the overall conversion of
NG825_18485	COG0697	spore germination
NG825_18520	COG0657	acetylesterase activity
NG825_18545	COG3485	protocatechuate 3,4-dioxygenase
NG825_18570	COG1187	pseudouridine synthase activity
NG825_18620	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NG825_18680	COG0842	Transport permease protein
NG825_18685	COG1131	(ABC) transporter
NG825_18720	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
NG825_18725	COG1573	uracil-dna glycosylase
NG825_18735	COG3384	dioxygenase
NG825_18740	COG0583	DNA-binding transcription factor activity
NG825_18755	COG0667	Aldo Keto reductase
NG825_18765	COG0667	Aldo Keto reductase
NG825_18780	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NG825_18785	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NG825_18835	COG4774	siderophore transport
NG825_18855	COG3275	phosphorelay sensor kinase activity
NG825_18865	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
NG825_18875	COG0531	amino acid
NG825_18895	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
NG825_18895	COG5297	Belongs to the glycosyl hydrolase family 6
NG825_18900	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
NG825_18900	COG5297	Belongs to the glycosyl hydrolase family 6
NG825_18905	COG0612	Peptidase, M16
NG825_18945	COG2207	Transcriptional regulator
NG825_18955	COG0598	Magnesium transport protein CorA
NG825_18970	COG0697	spore germination
NG825_18990	COG0583	DNA-binding transcription factor activity
NG825_18995	COG2249	NAD(P)H dehydrogenase (quinone) activity
NG825_19010	COG2409	Drug exporters of the RND superfamily
NG825_19020	COG5520	Belongs to the glycosyl hydrolase 30 family
NG825_19030	COG3550	peptidyl-serine autophosphorylation
NG825_19045	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
NG825_19165	COG2353	YceI-like domain
NG825_19170	COG0778	Nitroreductase
NG825_19190	COG0584	glycerophosphoryl diester phosphodiesterase
NG825_19210	COG0477	Major facilitator Superfamily
NG825_19215	COG2814	Major facilitator Superfamily
NG825_19220	COG0583	DNA-binding transcription factor activity
NG825_19240	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NG825_19250	COG0459	protein refolding
NG825_19255	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NG825_19265	COG1324	tolerance protein
NG825_19270	COG4232	protein-disulfide reductase activity
NG825_19275	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NG825_19290	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
NG825_19295	COG0511	ligase activity, forming carbon-carbon bonds
NG825_19305	COG0439	Biotin carboxylase
NG825_19320	COG2264	protein methyltransferase activity
NG825_19335	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
NG825_19340	COG4589	Belongs to the CDS family
NG825_19365	COG2453	phosphatase
NG825_19365	COG0671	phosphoesterase, PA-phosphatase related
NG825_19370	COG2267	carboxylic ester hydrolase activity
NG825_19375	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NG825_19380	COG0138	bifunctional purine biosynthesis protein purh
NG825_19390	COG0151	Belongs to the GarS family
NG825_19400	COG1289	transmembrane transporter activity
NG825_19455	COG2816	NAD+ diphosphatase activity
NG825_19460	COG0316	Belongs to the HesB IscA family
NG825_19500	COG1051	belongs to the nudix hydrolase family
NG825_19515	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
NG825_19540	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
NG825_19545	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NG825_19550	COG0730	response to heat
NG825_19555	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
NG825_19565	COG0134	indole-3-glycerol-phosphate synthase activity
NG825_19570	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NG825_19615	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
NG825_19620	COG0484	heat shock protein binding
NG825_19665	COG0651	ATP synthesis coupled electron transport
NG825_19670	COG1863	multisubunit Na H antiporter MnhE subunit
NG825_19675	COG2212	antiporter activity
NG825_19680	COG1320	monovalent cation:proton antiporter activity
NG825_19690	COG0753	catalase activity
NG825_19715	COG2197	response regulator
NG825_19720	COG4585	Histidine kinase
NG825_19730	COG1131	(ABC) transporter
NG825_19735	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NG825_19740	COG1136	(ABC) transporter
NG825_19745	COG0577	efflux transmembrane transporter activity
NG825_19765	COG0697	spore germination
NG825_19790	COG0180	Tryptophanyl-tRNA synthetase
NG825_19800	COG3237	CsbD-like
NG825_19815	COG0010	Belongs to the arginase family
NG825_19840	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
NG825_19885	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NG825_19940	COG1404	Belongs to the peptidase S8 family
NG825_19950	COG2814	Major facilitator Superfamily
NG825_19955	COG0583	DNA-binding transcription factor activity
NG825_19970	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NG825_19975	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NG825_20000	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
NG825_20005	COG1764	response to oxidative stress
NG825_20010	COG1846	Transcriptional regulator
NG825_20020	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
NG825_20030	COG0697	spore germination
NG825_20035	COG0523	cobalamin synthesis protein
NG825_20060	COG1960	acyl-CoA dehydrogenase activity
NG825_20065	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NG825_20105	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NG825_20105	COG1042	CoA-binding domain protein
NG825_20105	COG0045	succinate-CoA ligase (ADP-forming) activity
NG825_20115	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NG825_20120	COG3387	PFAM Glycoside hydrolase 15-related
NG825_20125	COG0745	RESPONSE REGULATOR receiver
NG825_20140	COG1404	Belongs to the peptidase S8 family
NG825_20155	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NG825_20165	COG0463	Glycosyl transferase, family 2
NG825_20180	COG1028	Short-chain dehydrogenase reductase Sdr
NG825_20210	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NG825_20225	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NG825_20260	COG1294	oxidase, subunit
NG825_20265	COG1271	oxidase subunit
NG825_20285	COG0408	coproporphyrinogen oxidase activity
NG825_20305	COG0589	response to stress
NG825_20325	COG3568	Endonuclease Exonuclease Phosphatase
NG825_20335	COG0392	lysyltransferase activity
NG825_20355	COG0210	DNA helicase
NG825_20360	COG0583	DNA-binding transcription factor activity
NG825_20365	COG0477	Major facilitator Superfamily
NG825_20380	COG0267	Belongs to the bacterial ribosomal protein bL33 family
NG825_20385	COG0227	Belongs to the bacterial ribosomal protein bL28 family
NG825_20425	COG0463	Glycosyl transferase, family 2
NG825_20450	COG1192	Involved in chromosome partitioning
NG825_20455	COG0357	Ribosomal RNA small subunit methyltransferase G
NG825_20465	COG2091	lysine biosynthetic process via aminoadipic acid
NG825_20490	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NG825_20505	COG1011	Hydrolase
NG825_20510	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NG825_20550	COG0457	Tetratricopeptide repeat
NG825_20555	COG0784	Response regulator, receiver
NG825_20555	COG2198	Histidine kinase
NG825_20555	COG2205	protein histidine kinase activity
NG825_20560	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NG825_20565	COG3265	gluconokinase activity
NG825_20570	COG2094	Belongs to the DNA glycosylase MPG family
NG825_20605	COG2911	Protein conserved in bacteria
NG825_20610	COG0729	surface antigen
NG825_20625	COG3132	Protein of unknown function, DUF480
NG825_20690	COG3210	domain, Protein
NG825_20690	COG3210	domain, Protein
NG825_20695	COG3210	domain, Protein
NG825_20710	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
NG825_20715	COG0284	orotidine-5'-phosphate decarboxylase activity
NG825_20730	COG1609	Transcriptional regulator
NG825_20815	COG0037	tRNA processing
NG825_20830	COG0840	transmembrane signaling receptor activity
NG825_20860	COG0805	protein transport
NG825_20870	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NG825_20870	COG0519	Catalyzes the synthesis of GMP from XMP
NG825_20875	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NG825_20890	COG0210	DNA helicase
NG825_20905	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
NG825_20910	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
NG825_20940	COG1119	ATPase activity
NG825_20945	COG1733	regulation of RNA biosynthetic process
NG825_20970	COG0594	ribonuclease P activity