locus-tag	class	description
SB85_00010	ENOG4108IJ8	ABC transporter
SB85_00020	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SB85_00025	ENOG4105C34	Pseudouridine synthase
SB85_00050	ENOG4105C8Q	Methyl-accepting chemotaxis
SB85_00055	ENOG4105C1K	alpha-alpha-trehalose-phosphate synthase
SB85_00060	ENOG4105BZP	glycoside hydrolase 15-related
SB85_00065	ENOG4108K4C	ec 3.1.3.12
SB85_00070	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
SB85_00105	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
SB85_00130	ENOG4105EU0	Major facilitator Superfamily
SB85_00140	ENOG4105VIF	phosphate starvation-inducible protein
SB85_00145	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
SB85_00150	ENOG4105DBM	Siderophore biosynthesis protein
SB85_00155	ENOG4105C6X	Major Facilitator
SB85_00170	ENOG4105GAV	receptor
SB85_00180	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
SB85_00200	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
SB85_00205	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
SB85_00210	ENOG4105C5H	ABC transporter
SB85_00220	ENOG4105ETT	transcriptional Regulator, LysR family
SB85_00235	ENOG4105HSS	phospholipase C
SB85_00255	ENOG4105C9M	aspartyl-trna synthetase
SB85_00285	ENOG4105CDY	transcriptional regulatory protein
SB85_00290	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
SB85_00295	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
SB85_00300	ENOG4105DFH	Transport of potassium into the cell (By similarity)
SB85_00305	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
SB85_00310	ENOG4107YD3	Thioesterase
SB85_00315	ENOG4105E02	MotA TolQ exbB proton channel
SB85_00320	ENOG4105M8F	Biopolymer transport protein exbD tolR
SB85_00330	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
SB85_00335	ENOG4105KCK	Peptidoglycan-associated lipoprotein
SB85_00345	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
SB85_00380	ENOG4105C9U	ATP-dependent DNA helicase RecQ
SB85_00405	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
SB85_00410	ENOG4105Z85	coenzyme PQQ synthesis
SB85_00415	ENOG41086XE	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ (By similarity)
SB85_00420	ENOG4105JIE	May be involved in the transport of PQQ or its precursor to the periplasm (By similarity)
SB85_00430	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
SB85_00440	ENOG4105CKK	Glycosyl transferase, family 2
SB85_00445	ENOG4105BZ4	penicillin-binding protein
SB85_00455	ENOG4105DVT	helicase
SB85_00460	ENOG41072GX	Peptidase M22 Glycoprotease
SB85_00470	ENOG4108KPZ	tonB-dependent Receptor
SB85_00480	ENOG4105D7Z	glutathione synthase
SB85_00485	ENOG4108UNF	response regulator
SB85_00490	ENOG4105M3Z	response regulator
SB85_00495	ENOG410807Z	Modulation of CheA activity in response to attractants (Chemotaxis
SB85_00500	ENOG4105C8Q	Methyl-accepting chemotaxis
SB85_00505	ENOG4105CBS	Chea signal transduction histidine kinase
SB85_00590	ENOG4105KVH	Transcriptional regulator
SB85_00615	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
SB85_00625	ENOG4107XZC	Restriction modification system DNA (Specificity
SB85_00635	ENOG4105CVR	type I restriction-modification system
SB85_00645	ENOG4107SCJ	type I restriction enzyme EcoKI subunit R
SB85_00660	ENOG4105CWX	Alpha-1,2-mannosidase
SB85_00670	ENOG4105F8D	glycoside hydrolase family 4
SB85_00680	ENOG4107QTZ	amino acid
SB85_00705	ENOG4105E2D	ec 3.2.1.52
SB85_00710	ENOG4105VRS	hydrolase family 18
SB85_00725	ENOG4105CHC	glucokinase (EC 2.7.1.2)
SB85_00730	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
SB85_00740	ENOG4107RK2	ADP-ribose diphosphatase NudE
SB85_00745	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
SB85_00750	ENOG4105DXN	mazG family
SB85_00755	ENOG4105KK4	UPF0060 membrane protein
SB85_00765	ENOG4107QX8	SPFH domain, Band 7 family protein
SB85_00775	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
SB85_00780	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
SB85_00815	ENOG4107QPN	acyl-Coa dehydrogenase
SB85_00825	ENOG4108IG5	Transcriptional regulator
SB85_00850	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
SB85_00860	ENOG41080XP	Cbs domain
SB85_00870	ENOG4108UT2	hemolysin iii
SB85_00875	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
SB85_00880	ENOG4105DR5	peptidase
SB85_00885	ENOG4106TYC	homoserine o-acetyltransferase (EC 2.3.1.31)
SB85_00890	ENOG4105C28	cystathionine
SB85_00895	ENOG4105CFH	Aspartokinase
SB85_00900	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
SB85_00905	ENOG4105BZU	Histidine kinase
SB85_00910	ENOG4105EJQ	L-serine dehydratase
SB85_00920	ENOG4108TGY	Glutathione S-transferase
SB85_00945	ENOG4105DWF	phosphomethylpyrimidine kinase
SB85_00960	ENOG4108IAB	Phoh family
SB85_00965	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
SB85_00975	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
SB85_00985	ENOG4108Z4U	Ferredoxin
SB85_00990	ENOG4105EI3	2-dehydro-3-deoxygalactonokinase EC 2.7.1.58
SB85_01000	ENOG4105CXK	mandelate racemase muconate lactonizing
SB85_01005	ENOG4108RTU	Aldolase
SB85_01035	ENOG4105CMG	Carbohydrate kinase
SB85_01040	ENOG4105C93	Xylose Isomerase
SB85_01050	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
SB85_01060	ENOG4105DJ0	Poly(A) Polymerase
SB85_01065	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
SB85_01070	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
SB85_01075	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
SB85_01085	ENOG4107QP8	phosphohexose isomerase
SB85_01105	ENOG4105BZU	Histidine kinase
SB85_01115	ENOG4105TX3	Histidine kinase
SB85_01120	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
SB85_01125	ENOG410841Q	phosphoesterase PA-phosphatase related protein
SB85_01150	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
SB85_01165	ENOG4105C26	Dehydrogenase
SB85_01195	ENOG4105D98	threonine synthase
SB85_01205	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
SB85_01215	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
SB85_01220	ENOG4105CUT	histidyl-tRNA synthetase
SB85_01240	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
SB85_01245	ENOG4105CIH	Imidazole acetol-phosphate transaminase
SB85_01255	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
SB85_01260	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
SB85_01265	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
SB85_01270	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
SB85_01285	ENOG4106YVY	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) (By similarity)
SB85_01290	ENOG4108CAF	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity)
SB85_01295	ENOG4107QY0	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity)
SB85_01300	ENOG4105CUB	amino acid
SB85_01305	ENOG4105CUB	amino acid
SB85_01315	ENOG4108JQ1	Dehydrogenase
SB85_01320	ENOG4105CQB	FAD linked oxidase domain protein
SB85_01340	ENOG4105FUQ	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
SB85_01350	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
SB85_01360	ENOG4105E39	Enoyl-CoA hydratase
SB85_01370	ENOG4105CE1	Ferrous iron transport protein b
SB85_01385	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
SB85_01400	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
SB85_01410	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
SB85_01415	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
SB85_01425	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
SB85_01430	ENOG4108JJA	ABC, transporter
SB85_01460	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
SB85_01465	ENOG4105CRK	lysyL-tRNA synthetase
SB85_01470	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
SB85_01480	ENOG4105E39	Enoyl-CoA hydratase
SB85_01485	ENOG4105CEY	Amp-dependent synthetase and ligase
SB85_01490	ENOG4107QM5	aconitate hydratase
SB85_01505	ENOG4107QIJ	Aconitate hydratase 2
SB85_01510	ENOG4105BZU	Histidine kinase
SB85_01515	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
SB85_01520	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
SB85_01535	ENOG4105C8Q	Methyl-accepting chemotaxis
SB85_01545	ENOG4108V3W	Chemotaxis protein, CheW
SB85_01555	ENOG4105C8Q	Methyl-accepting chemotaxis
SB85_01565	ENOG4105C8Q	Methyl-accepting chemotaxis
SB85_01570	ENOG4105C8Q	Methyl-accepting chemotaxis
SB85_01575	ENOG4105C8Q	Methyl-accepting chemotaxis
SB85_01580	ENOG4105C8Q	Methyl-accepting chemotaxis
SB85_01590	ENOG4105C8Q	Methyl-accepting chemotaxis
SB85_01595	ENOG4105C8Q	Methyl-accepting chemotaxis
SB85_01605	ENOG4105C8Q	Methyl-accepting chemotaxis
SB85_01610	ENOG4105C8Q	Methyl-accepting chemotaxis
SB85_01615	ENOG4105CBS	Chea signal transduction histidine kinase
SB85_01620	ENOG4108VYJ	response regulator receiver protein
SB85_01640	ENOG4107QJE	Chromosome Partitioning Protein
SB85_01650	ENOG4105E14	MotA TolQ exbB proton channel
SB85_01655	ENOG4105CBS	Chea signal transduction histidine kinase
SB85_01660	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
SB85_01665	ENOG4108VYJ	response regulator receiver protein
SB85_01670	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
SB85_01675	ENOG4107R21	site-determining protein
SB85_01685	ENOG4105FZW	flagellar biosynthesis regulator FlhF
SB85_01700	ENOG4105BZU	Histidine kinase
SB85_01705	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
SB85_01715	ENOG4105CN7	Flagellar biosynthetic protein FliP
SB85_01750	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
SB85_01755	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
SB85_01760	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
SB85_01765	ENOG4107RGC	Glycosyl transferase, family 2
SB85_01790	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
SB85_01795	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
SB85_01810	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
SB85_01815	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
SB85_01820	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
SB85_01825	ENOG4105WH1	Two component transcriptional regulator luxr family
SB85_01840	ENOG4105MQ3	flagellar protein FliS
SB85_01860	ENOG4105I03	Flagellin
SB85_01885	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
SB85_01890	ENOG4105CGA	flagellar basal-body rod protein FlgG
SB85_01895	ENOG4108KPB	Flagellar basal-body rod protein FlgF
SB85_01900	ENOG4105BZE	flagellar hook protein, FlgE
SB85_01910	ENOG4108ZC9	flagellar basal-body rod protein flgc
SB85_01920	ENOG4107R88	Chemotaxis protein (CheV)
SB85_01940	ENOG4105BZU	Histidine kinase
SB85_01945	ENOG4105BZU	Histidine kinase
SB85_01955	ENOG4105BZU	Histidine kinase
SB85_01990	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
SB85_02005	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
SB85_02010	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
SB85_02015	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
SB85_02020	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
SB85_02045	ENOG4105C3M	thioredoxin reductase
SB85_02050	ENOG4105CNU	cell division protein FtsK
SB85_02060	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
SB85_02065	ENOG4105PGM	cation diffusion facilitator family transporter
SB85_02070	ENOG4105D1H	recombination factor protein RarA
SB85_02110	ENOG4108VYJ	response regulator receiver protein
SB85_02115	ENOG4108M1T	Cytochrome c-type biogenesis protein
SB85_02120	ENOG4105KWW	Biogenesis protein
SB85_02125	ENOG4107QX9	Thiol disulfide interChange protein
SB85_02130	ENOG4105DA4	cytochrome c-type biogenesis protein
SB85_02145	ENOG41060IM	Heme exporter protein
SB85_02160	ENOG4105EMN	RNA polymerase sigma factor
SB85_02170	ENOG4105R2D	cytochrome C
SB85_02210	ENOG4105EGZ	biosynthesis protein
SB85_02215	ENOG4105K64	Glycosyl transferase, family 2
SB85_02250	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
SB85_02275	ENOG4105BZ1	(ABC) transporter
SB85_02300	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
SB85_02440	ENOG4105F2I	Transposase
SB85_02455	ENOG4105DEG	Vwa containing coxe family protein
SB85_02465	ENOG4105KKX	ATPase associated with various cellular activities aaa_5
SB85_02485	ENOG4105EB3	Histidine kinase
SB85_02490	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
SB85_02495	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
SB85_02580	ENOG4105BZU	Histidine kinase
SB85_02585	ENOG4105BZM	domain protein
SB85_02590	ENOG4105BZU	Histidine kinase
SB85_02600	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
SB85_02610	ENOG41067S9	phage shock protein C, PspC
SB85_02615	ENOG4105M0Y	
SB85_02620	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
SB85_02630	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
SB85_02665	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
SB85_02670	ENOG4108Z6B	deaminase
SB85_02675	ENOG4105KST	dependent repressor
SB85_02680	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
SB85_02735	ENOG4105DUM	transcriptional regulator, lysR family
SB85_02750	ENOG4105KVH	Transcriptional regulator
SB85_02755	ENOG4107Y3V	-acetyltransferase
SB85_02770	ENOG4105CAU	Arsenical resistance protein, ArsH
SB85_02775	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
SB85_02780	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
SB85_02785	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
SB85_02795	ENOG4107XM9	(LipO)protein
SB85_02800	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
SB85_02805	ENOG4105D06	uba thif-type nad fad binding protein
SB85_02815	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
SB85_02820	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
SB85_02825	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
SB85_02830	ENOG4105N21	Membrane
SB85_02835	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
SB85_02845	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
SB85_02850	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
SB85_02865	ENOG4105CHU	acetyl-coa acetyltransferase
SB85_02870	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
SB85_02880	ENOG4105ESV	Glycosyl transferase, family 4
SB85_02885	ENOG4105CFV	Tetratricopeptide repeat protein
SB85_02895	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
SB85_02900	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
SB85_02910	ENOG4105YK5	50S ribosomal protein L36
SB85_02920	ENOG4105DWY	Agmatine deiminase
SB85_02945	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
SB85_02965	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
SB85_02980	ENOG4105DUN	Mediates zinc uptake. May also transport other divalent cations (By similarity)
SB85_02985	ENOG4108NST	exported protein
SB85_02990	ENOG4105EI2	Pseudouridine synthase
SB85_03055	ENOG4105CC0	LysR family Transcriptional regulator
SB85_03090	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
SB85_03095	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
SB85_03100	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
SB85_03135	ENOG4105PDP	Short chain dehydrogenase
SB85_03150	ENOG4105CI2	imidazolone-5-propionate hydrolase
SB85_03165	ENOG4105CGP	Urocanate hydratase
SB85_03200	ENOG4105DZG	Dehydrogenase
SB85_03205	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
SB85_03210	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
SB85_03230	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
SB85_03235	ENOG4105CIH	Imidazole acetol-phosphate transaminase
SB85_03255	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
SB85_03265	ENOG4108Z4V	iron-sulfur cluster assembly
SB85_03270	ENOG4105C5S	asparaginyl-tRNA synthetase
SB85_03290	ENOG41077A9	carbonic anhydrase
SB85_03295	ENOG4105C3W	Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate (By similarity)
SB85_03305	ENOG4105CKY	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively (By similarity)
SB85_03310	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
SB85_03315	ENOG4105CJB	Exodeoxyribonuclease I
SB85_03340	ENOG4105IH7	synthase
SB85_03350	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
SB85_03360	ENOG4105C7I	Dehydrogenase
SB85_03370	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
SB85_03375	ENOG4105BZS	acriflavin resistance protein
SB85_03380	ENOG4105C1G	acyl-Coa dehydrogenase
SB85_03390	ENOG4105C3R	Methionine synthase
SB85_03395	ENOG4105C3R	Methionine synthase
SB85_03410	ENOG4105EXC	Acyl-transferase
SB85_03420	ENOG41069P5	Protein slyX homolog
SB85_03425	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
SB85_03430	ENOG4108V1T	peptidylprolyl cis-trans isomerase
SB85_03435	ENOG4108V06	Glutathione peroxidase
SB85_03445	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
SB85_03450	ENOG4105CZV	ABC transporter
SB85_03470	ENOG4105T38	integral membrane protein
SB85_03475	ENOG4105CHM	Aminotransferase
SB85_03495	ENOG4105C37	(CBS) domain
SB85_03500	ENOG4107QTF	adenylosuccinate lyase
SB85_03510	ENOG4105EZE	Cupin 4 family protein
SB85_03520	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
SB85_03525	ENOG4105C7S	Dehydrogenase
SB85_03535	ENOG4108URH	decarboxylase
SB85_03540	ENOG4105BZU	Histidine kinase
SB85_03560	ENOG4105BZ1	(ABC) transporter
SB85_03580	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
SB85_03590	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
SB85_03595	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
SB85_03600	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
SB85_03605	ENOG41090R7	Ferric uptake
SB85_03610	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
SB85_03625	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
SB85_03645	ENOG4105BZU	Histidine kinase
SB85_03680	ENOG4105EJC	lysr family transcriptional regulator
SB85_03695	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
SB85_03705	ENOG4105CDU	Replicative dna helicase
SB85_03715	ENOG4108RXX	maleylacetoacetate isomerase
SB85_03725	ENOG4105C1G	acyl-Coa dehydrogenase
SB85_03740	ENOG4105F8V	Hydrolase, tatD family
SB85_03750	ENOG4105CUZ	uba thif-type nad fad binding protein
SB85_03765	ENOG4105VEQ	Cold shock protein
SB85_03775	ENOG4105HDD	phospholipase
SB85_03790	ENOG4108RXX	maleylacetoacetate isomerase
SB85_03795	ENOG4107GFK	fumarate
SB85_03800	ENOG4108KPJ	rna polymerase sigma factor
SB85_03805	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
SB85_03830	ENOG4105DP0	ferredoxin-NADP reductase
SB85_03840	ENOG4105DGW	oligopeptidase A
SB85_03890	ENOG4105DUX	Transporter
SB85_03910	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
SB85_03925	ENOG4105C5H	ABC transporter
SB85_03930	ENOG4105C1J	atp-dependent rna helicase
SB85_03935	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
SB85_03945	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
SB85_03965	ENOG4108K3A	Glutathione S-transferase
SB85_03970	ENOG4105VEQ	Cold shock protein
SB85_03975	ENOG4108VWS	Yaeq family
SB85_03980	ENOG4105CBX	hi0933 family
SB85_03990	ENOG4105D0M	Protease HtpX homolog
SB85_03995	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
SB85_04000	ENOG4105CHR	reductase
SB85_04025	ENOG4105K8N	protein family UPF0079, ATPase
SB85_04030	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
SB85_04040	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
SB85_04050	ENOG4105QNF	Outer membrane lipoprotein
SB85_04070	ENOG4108T3F	Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes
SB85_04090	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
SB85_04095	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
SB85_04120	ENOG4105WH1	Two component transcriptional regulator luxr family
SB85_04125	ENOG4105CSU	acyl-Coa dehydrogenase
SB85_04170	ENOG4107Y2G	Glycosyl transferase (Group 1
SB85_04175	ENOG4107UFF	group 1 glycosyl transferase
SB85_04190	ENOG4105D3Q	Sugar transferase
SB85_04210	ENOG4105WJX	transcriptional regulator MERR family
SB85_04215	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
SB85_04220	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
SB85_04225	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
SB85_04230	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
SB85_04235	ENOG41082NX	50s ribosomal protein l35
SB85_04240	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
SB85_04245	ENOG4105C22	threonyL-tRNA synthetase
SB85_04250	ENOG4105ETE	Transcriptional regulator (LacI family
SB85_04280	ENOG4105CG3	alpha amylase, catalytic region
SB85_04290	ENOG4105F0V	Cell wall hydrolase
SB85_04365	ENOG4105CMA	conjugation trbi family protein
SB85_04400	ENOG4105KHS	type IV fimbrial pilin protein
SB85_04435	ENOG4105X0D	Fimbrial protein
SB85_04445	ENOG4105EWT	decarboxylase family
SB85_04450	ENOG4108KPZ	tonB-dependent Receptor
SB85_04460	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
SB85_04465	ENOG4107SEV	1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase
SB85_04470	ENOG4105M2J	Glutaredoxin
SB85_04475	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
SB85_04480	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
SB85_04485	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
SB85_04495	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
SB85_04510	ENOG4105KB2	stringent starvation protein b
SB85_04515	ENOG4107MKT	Stringent starvation protein a
SB85_04520	ENOG4105EIX	cytochrome c1
SB85_04530	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
SB85_04550	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
SB85_04585	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
SB85_04595	ENOG4108JU5	Magnesium and cobalt efflux protein
SB85_04610	ENOG4105C26	Dehydrogenase
SB85_04615	ENOG4105D38	putrescine abc transporter
SB85_04620	ENOG4105F38	ABC transporter, permease
SB85_04625	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
SB85_04650	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
SB85_04665	ENOG4105CFQ	glutamine synthetase
SB85_04670	ENOG4108Z86	Glutamine amidotransferase
SB85_04675	ENOG4105CFQ	glutamine synthetase
SB85_04680	ENOG4105CJP	fad dependent oxidoreductase
SB85_04685	ENOG4105BZU	Histidine kinase
SB85_04690	ENOG4105CSH	Transporter
SB85_04700	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
SB85_04705	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
SB85_04725	ENOG4105C26	Dehydrogenase
SB85_04730	ENOG4107VRI	Transcriptional regulator
SB85_04735	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
SB85_04740	ENOG4105DCF	alanine dehydrogenase
SB85_04755	ENOG4106BRA	Membrane
SB85_04765	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
SB85_04770	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
SB85_04775	ENOG4105C5H	ABC transporter
SB85_04805	ENOG4105KHC	sulfurtransferase
SB85_04810	ENOG4105P8F	nudix hydrolase
SB85_04815	ENOG4108V1T	peptidylprolyl cis-trans isomerase
SB85_04820	ENOG4105E39	Enoyl-CoA hydratase
SB85_04830	ENOG4105CSM	endonuclease III
SB85_04840	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
SB85_04845	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
SB85_04855	ENOG4105E2Z	phosphate ABC transporter (Permease
SB85_04860	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
SB85_04865	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
SB85_04875	ENOG4105E18	UPF0276 protein
SB85_04885	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
SB85_04900	ENOG4105BZU	Histidine kinase
SB85_04905	ENOG4105C2N	RNA methyltransferase TrmH family group 3
SB85_04915	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
SB85_04950	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
SB85_04955	ENOG4105CW7	secretion protein, HlyD family
SB85_04975	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
SB85_05000	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
SB85_05005	ENOG4105FB2	class II Aldolase
SB85_05010	ENOG4105CMG	Carbohydrate kinase
SB85_05025	ENOG4108UWD	Iron-storage protein
SB85_05040	ENOG4105KDM	Diguanylate cyclase with gaf sensor
SB85_05055	ENOG4105CAQ	asparagine synthetase
SB85_05070	ENOG4105KUZ	arsenate reductase
SB85_05085	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
SB85_05090	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
SB85_05125	ENOG4105CE9	30S ribosomal protein S2
SB85_05135	ENOG4105BZU	Histidine kinase
SB85_05140	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
SB85_05145	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
SB85_05150	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
SB85_05155	ENOG4105KNE	Phosphatidate cytidylyltransferase
SB85_05165	ENOG4105DZP	Membrane-associated zinc metalloprotease
SB85_05170	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SB85_05175	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
SB85_05185	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
SB85_05190	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
SB85_05195	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
SB85_05210	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
SB85_05220	ENOG4108YXA	Membrane
SB85_05315	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
SB85_05320	ENOG4105E08	Glycoside hydrolase, family 9
SB85_05325	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
SB85_05330	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
SB85_05335	ENOG4105BZS	acriflavin resistance protein
SB85_05345	ENOG4105GR3	Histidine kinase
SB85_05350	ENOG4105C8F	Beta-lactamase domain protein
SB85_05355	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
SB85_05360	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
SB85_05385	ENOG4106H78	methyltransferase
SB85_05390	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
SB85_05395	ENOG4105DG4	malate L-lactate dehydrogenase
SB85_05415	ENOG4107PMW	Arabinan endo-1,5-alpha-L-arabinosidase
SB85_05425	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
SB85_05445	ENOG4107QTZ	amino acid
SB85_05460	ENOG4105DC7	peptidase M24
SB85_05470	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
SB85_05485	ENOG41080HI	glycine oxidase
SB85_05490	ENOG4105CTU	Proline racemase
SB85_05500	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
SB85_05505	ENOG4105CEN	a g-specific adenine glycosylase
SB85_05550	ENOG4108V3W	Chemotaxis protein, CheW
SB85_05555	ENOG4105C8Q	Methyl-accepting chemotaxis
SB85_05560	ENOG4105C8Q	Methyl-accepting chemotaxis
SB85_05575	ENOG4105BZU	Histidine kinase
SB85_05580	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
SB85_05585	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
SB85_05595	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
SB85_05605	ENOG4105CHV	Transcription elongation factor NusA
SB85_05620	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
SB85_05625	ENOG4105C8S	subunit m
SB85_05630	ENOG4105D65	subunit l
SB85_05640	ENOG4105DF2	NADH dehydrogenase subunit j
SB85_05645	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
SB85_05650	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
SB85_05655	ENOG4108IEH	NADH dehydrogenase subunit g
SB85_05660	ENOG4107QIZ	NADH dehydrogenase
SB85_05665	ENOG4105GKE	subunit e
SB85_05675	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
SB85_05680	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
SB85_05685	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
SB85_05700	ENOG4105CP7	Triose-phosphate isomerase
SB85_05705	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
SB85_05745	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
SB85_05755	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
SB85_05760	ENOG4108MGI	Transcriptional regulator
SB85_05765	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
SB85_05770	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
SB85_05785	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
SB85_05790	ENOG4105C5I	Dehydrogenase
SB85_05800	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
SB85_05810	ENOG4105DJ4	phosphatidylserine decarboxylase
SB85_05815	ENOG4106770	Is able to cleave peptidoglycan (By similarity)
SB85_05820	ENOG4105D7A	ATP-binding protein
SB85_05830	ENOG4107VIJ	nudix hydrolase
SB85_05845	ENOG4108RRZ	Transcription elongation factor GreB
SB85_05885	ENOG4105DHP	deoxycytidine triphosphate deaminase
SB85_05910	ENOG4105C9K	Endothelin-converting enzyme 1
SB85_05945	ENOG4108YZY	peptidylprolyl cis-trans isomerase
SB85_05950	ENOG4105K4H	Nlp p60 protein
SB85_05955	ENOG4105K4H	Nlp p60 protein
SB85_05960	ENOG4107UA9	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) (By similarity)
SB85_05980	ENOG4105CK2	sodium dicarboxylate symporter
SB85_05985	ENOG4105G6Z	alkaline phosphatase
SB85_06000	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
SB85_06005	ENOG4105CTB	Polyprenyl synthetase
SB85_06035	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
SB85_06045	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
SB85_06055	ENOG4105C03	ribonuclease
SB85_06060	ENOG4108Z03	MAF-like protein
SB85_06065	ENOG4105MPN	Membrane
SB85_06080	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
SB85_06095	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
SB85_06120	ENOG4107QR8	Thioredoxin
SB85_06150	ENOG4107QK5	Homocysteine s-methyltransferase
SB85_06160	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
SB85_06170	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
SB85_06200	ENOG4105K6V	RNA polymerase
SB85_06225	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
SB85_06245	ENOG4105M4H	endoribonuclease L-psp
SB85_06295	ENOG4105F27	Major Facilitator
SB85_06300	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
SB85_06305	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
SB85_06315	ENOG4108YZY	peptidylprolyl cis-trans isomerase
SB85_06350	ENOG4105KSC	Transcriptional regulator, TraR DksA family
SB85_06360	ENOG4108VKG	metal-dependent hydrolase
SB85_06365	ENOG4105FE9	pseudouridine synthase
SB85_06375	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
SB85_06380	ENOG4105D05	Receptor
SB85_06400	ENOG4105DZP	Membrane-associated zinc metalloprotease
SB85_06415	ENOG4105D5P	Methylmalonyl-coA mutase
SB85_06435	ENOG4105CHU	acetyl-coa acetyltransferase
SB85_06460	ENOG4105CSU	acyl-Coa dehydrogenase
SB85_06465	ENOG4107T0X	DNA ligase
SB85_06470	ENOG4107T0X	DNA ligase
SB85_06475	ENOG4107QRT	dEAD DEAH box helicase
SB85_06490	ENOG41061H0	Monooxygenase
SB85_06495	ENOG4105VEQ	Cold shock protein
SB85_06500	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
SB85_06505	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
SB85_06510	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
SB85_06520	ENOG41080ZE	Adenylate cyclase
SB85_06525	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
SB85_06535	ENOG4107ENK	receptor
SB85_06545	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
SB85_06550	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
SB85_06560	ENOG4105C3F	Signal peptidase i
SB85_06565	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
SB85_06570	ENOG4105C0H	protease
SB85_06580	ENOG4105EMN	RNA polymerase sigma factor
SB85_06585	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
SB85_06600	ENOG4105HMI	Membrane
SB85_06615	ENOG4106FKC	arabinogalactan endo-1,4-beta-galactosidase
SB85_06630	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
SB85_06635	ENOG4108RXX	maleylacetoacetate isomerase
SB85_06645	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
SB85_06655	ENOG4105VEJ	Heat shock protein
SB85_06660	ENOG4107QJQ	Mate efflux family protein
SB85_06665	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
SB85_06675	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
SB85_06680	ENOG4105K5M	30s ribosomal protein S16
SB85_06690	ENOG4105EA8	2-Nitropropane dioxygenase
SB85_06705	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
SB85_06710	ENOG4105CRE	cytochrome C
SB85_06725	ENOG4105CZZ	Alpha-N-arabinofuranosidase (EC 3.2.1.55)
SB85_06740	ENOG4108NVJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
SB85_06755	ENOG4108TGY	Glutathione S-transferase
SB85_06765	ENOG41062B0	ABC transporter, permease
SB85_06770	ENOG4107R9N	ABC transporter
SB85_06775	ENOG4105C2J	ABC transporter
SB85_06780	ENOG4107R5U	Periplasmic binding protein LacI transcriptional regulator
SB85_06785	ENOG4105C26	Dehydrogenase
SB85_06800	ENOG4105FGE	Short-chain dehydrogenase reductase Sdr
SB85_06805	ENOG4105C01	Dihydroxy-acid dehydratase
SB85_06810	ENOG4108SF5	RNA Polymerase
SB85_06820	ENOG4105CNM	Receptor
SB85_06825	ENOG4105D6F	Phosphatase
SB85_06845	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
SB85_06855	ENOG4108S10	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
SB85_06860	ENOG4108KPJ	rna polymerase sigma factor
SB85_06865	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
SB85_06870	ENOG4105CCU	oxidase (Subunit III)
SB85_06875	ENOG4105BZ9	Cytochrome C oxidase, subunit I
SB85_06880	ENOG4105E2S	oxidase) subunit II
SB85_06900	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
SB85_06905	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
SB85_06910	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
SB85_06915	ENOG4105DTN	riboflavin biosynthesis protein ribF
SB85_06920	ENOG4105CJR	Integral membrane protein (MviN
SB85_06925	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
SB85_06940	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
SB85_06945	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
SB85_06950	ENOG4108TGP	Thioesterase superfamily protein
SB85_06960	ENOG4105E39	Enoyl-CoA hydratase
SB85_06965	ENOG4105C29	acyl-CoA thioesterase
SB85_06980	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
SB85_06995	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
SB85_07015	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
SB85_07020	ENOG4105FUY	alpha subunit
SB85_07045	ENOG4105F6J	Alpha beta hydrolase fold
SB85_07090	ENOG4105BZU	Histidine kinase
SB85_07105	ENOG4107QMS	site-determining protein
SB85_07110	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
SB85_07120	ENOG4105C08	Histidine kinase
SB85_07125	ENOG4105ETX	regulatoR
SB85_07135	ENOG4105DIJ	Phosphoethanolamine transferase
SB85_07155	ENOG4105C2C	drug resistance transporter, Bcr CflA
SB85_07160	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
SB85_07170	ENOG4105E2A	Dehydrogenase
SB85_07230	ENOG4105DZR	Type I site-specific deoxyribonuclease
SB85_07235	ENOG4105CB5	ATP-dependent DNA helicase recG
SB85_07245	ENOG4105CVR	type I restriction-modification system
SB85_07280	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
SB85_07290	ENOG4105EPW	hflc protein
SB85_07295	ENOG4107QJR	hflk protein
SB85_07305	ENOG4105M3Z	response regulator
SB85_07335	ENOG4108JQB	penicillin-binding protein 1C
SB85_07340	ENOG4105BZU	Histidine kinase
SB85_07355	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
SB85_07380	ENOG4105DN3	alpha-2-macroglobulin domain protein
SB85_07400	ENOG4105C7F	AcnD-accessory protein PrpF
SB85_07405	ENOG4108I0Z	Aconitate hydratase
SB85_07410	ENOG4105BZN	citrate synthase
SB85_07420	ENOG4105CR4	methylisocitrate lyase
SB85_07445	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
SB85_07460	ENOG4105C0B	DNA polymerase III (alpha subunit)
SB85_07470	ENOG4105VTW	prevent-host-death family
SB85_07475	ENOG4105KRQ	Addiction module toxin, Txe YoeB family
SB85_07490	ENOG4107QRG	dna polymerase iii
SB85_07495	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
SB85_07500	ENOG4105HHA	aminodeoxychorismate lyase
SB85_07510	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
SB85_07520	ENOG4105CHR	reductase
SB85_07525	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
SB85_07535	ENOG4105VGS	50s ribosomal protein l32
SB85_07540	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
SB85_07555	ENOG41089I4	Inherit from COG: Glycosyl transferase, family 2
SB85_07565	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
SB85_07575	ENOG4105F8C	transglutaminase domain-containing protein
SB85_07585	ENOG4105K59	histidine triad (HIT) protein
SB85_07590	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
SB85_07600	ENOG4107QMP	dna polymerase iii subunits gamma and tau
SB85_07615	ENOG4105M00	molybdopterin converting factor, subunit 1
SB85_07630	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
SB85_07635	ENOG4107UV6	ribonuclease Z
SB85_07640	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
SB85_07645	ENOG4105DKP	glycosyl transferase, family 9
SB85_07665	ENOG4108ZF3	Phosphatase
SB85_07670	ENOG4108JDX	DNA polymerase iii, epsilon subunit
SB85_07675	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
SB85_07685	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
SB85_07695	ENOG4105EIN	peptidylprolyl cis-trans isomerase
SB85_07725	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
SB85_07730	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
SB85_07735	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
SB85_07775	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
SB85_07790	ENOG4105ERG	peptidase m48, ste24p
SB85_07795	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
SB85_07800	ENOG4105BZU	Histidine kinase
SB85_07810	ENOG4105C9X	ppx gppa phosphatase
SB85_07815	ENOG4105BZF	Glycosyl transferase (Group 1
SB85_07825	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
SB85_07835	ENOG4108YP4	Metalloprotease, specifically cleaves on the N-terminal side of aspartyl, glutamyl and cysteic acid residues (By similarity)
SB85_07840	ENOG4105ED9	Protein of unknown function (DUF455)
SB85_07850	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
SB85_07865	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
SB85_07870	ENOG4107RPC	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
SB85_07880	ENOG4105CPQ	Dehydrogenase
SB85_07890	ENOG4108IJ6	ABC transporter
SB85_07900	ENOG4108I5D	sulfate abc transporter
SB85_07905	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
SB85_07920	ENOG4108R99	pseudouridine synthase
SB85_07930	ENOG4105CDV	Ompa motb domain protein
SB85_07935	ENOG4105EJC	lysr family transcriptional regulator
SB85_07950	ENOG4105CPC	Aldo Keto reductase
SB85_07955	ENOG4105CIS	alcohol dehydrogenase
SB85_07980	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
SB85_08000	ENOG4108K3A	Glutathione S-transferase
SB85_08005	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
SB85_08020	ENOG4108K3A	Glutathione S-transferase
SB85_08030	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
SB85_08040	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
SB85_08065	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
SB85_08080	ENOG41080I0	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
SB85_08085	ENOG4108ZT0	50S ribosomal protein l17
SB85_08090	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
SB85_08095	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
SB85_08100	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
SB85_08105	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
SB85_08110	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
SB85_08115	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
SB85_08120	ENOG41087MT	50S ribosomal protein L30
SB85_08125	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
SB85_08130	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
SB85_08145	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
SB85_08150	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
SB85_08155	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
SB85_08160	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
SB85_08165	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
SB85_08175	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
SB85_08180	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
SB85_08185	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
SB85_08190	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
SB85_08195	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
SB85_08200	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
SB85_08205	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
SB85_08215	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
SB85_08220	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
SB85_08225	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
SB85_08230	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
SB85_08235	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
SB85_08240	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
SB85_08250	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
SB85_08260	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
SB85_08265	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
SB85_08270	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
SB85_08275	ENOG4105PM1	preprotein translocase subunit SecE
SB85_08285	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
SB85_08305	ENOG4105C3G	gtp-binding protein
SB85_08310	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
SB85_08315	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
SB85_08320	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
SB85_08330	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
SB85_08340	ENOG4105DJQ	tetratricopeptide tpr_2 repeat protein
SB85_08350	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
SB85_08370	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
SB85_08380	ENOG4105CSR	polyphosphate kinase 2
SB85_08390	ENOG4107S2Z	UPF0761 membrane protein
SB85_08395	ENOG4105CS1	NAD(P)H quinone oxidoreductase
SB85_08410	ENOG4108Z66	YbaK ebsC protein
SB85_08415	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
SB85_08420	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
SB85_08425	ENOG4105CM2	brancheD-chain amino acid aminotransferase
SB85_08440	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
SB85_08445	ENOG4105W8H	transhydrogenase (subunit alpha
SB85_08465	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
SB85_08485	ENOG4105C2M	dna polymerase I
SB85_08505	ENOG4105CR8	Transcriptional regulator
SB85_08530	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
SB85_08545	ENOG4105C5Q	Transcriptional regulator
SB85_08550	ENOG4105NXH	GreA GreB family elongation factor
SB85_08555	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
SB85_08575	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
SB85_08590	ENOG4105BZU	Histidine kinase
SB85_08595	ENOG4105BZU	Histidine kinase
SB85_08605	ENOG4105CX6	glutaminyL-tRNA synthetase
SB85_08615	ENOG4105DXC	membrane
SB85_08635	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
SB85_08670	ENOG4105D0A	hydroxylase
SB85_08675	ENOG4105D0A	hydroxylase
SB85_08685	ENOG4108WBT	adenosyltransferase
SB85_08690	ENOG4105DGU	Histone deacetylase
SB85_08705	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
SB85_08715	ENOG4105NWN	ApaG protein
SB85_08720	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
SB85_08730	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
SB85_08750	ENOG4108V0P	LemA family
SB85_08755	ENOG4105EE5	Membrane protein terC
SB85_08760	ENOG41080IJ	Diacylglycerol kinase
SB85_08770	ENOG4105DHQ	Histidine kinase
SB85_08775	ENOG4105ETX	regulatoR
SB85_08780	ENOG4108UJV	acyl-CoA thioesterase i
SB85_08785	ENOG4108I0Y	(ABC) transporter
SB85_08790	ENOG4105CV6	ABC transporter, permease
SB85_08805	ENOG4105D05	Receptor
SB85_08815	ENOG4105CPC	Aldo Keto reductase
SB85_08820	ENOG4105D9N	nucleoside
SB85_08835	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
SB85_08840	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
SB85_08880	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
SB85_08915	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
SB85_08980	ENOG4105SYT	Methylenetetrahydrofolate reductase
SB85_08990	ENOG4105M6F	mutator MutT protein
SB85_09005	ENOG4105DR5	peptidase
SB85_09020	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
SB85_09025	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
SB85_09030	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
SB85_09035	ENOG4105CPF	Cell wall formation (By similarity)
SB85_09040	ENOG4105DFU	Cell wall formation (By similarity)
SB85_09045	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
SB85_09055	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
SB85_09060	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
SB85_09065	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
SB85_09070	ENOG4105CJN	penicillin-binding protein
SB85_09075	ENOG4106932	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
SB85_09080	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
SB85_09085	ENOG4108V6E	Cell division protein mraZ
SB85_09115	ENOG41082RQ	UPF0102 protein
SB85_09120	ENOG4105S2T	inner membrane protein YbcI
SB85_09125	ENOG4105CQB	FAD linked oxidase domain protein
SB85_09130	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
SB85_09135	ENOG4105C08	Histidine kinase
SB85_09145	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
SB85_09150	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
SB85_09170	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
SB85_09175	ENOG4107YIM	Involved in the transcription termination process (By similarity)
SB85_09180	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
SB85_09185	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
SB85_09195	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
SB85_09205	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
SB85_09210	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
SB85_09310	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
SB85_09315	ENOG4105EJG	cellulose synthase
SB85_09320	ENOG4105K2Z	endo-1,4-d-glucanase (EC 3.2.1.4)
SB85_09325	ENOG4107EEX	Cellulose synthase regulator protein
SB85_09330	ENOG4107QZ7	Cellulose synthase catalytic subunit
SB85_09345	ENOG4107RH7	Nicotinate phosphoribosyltransferase
SB85_09395	ENOG4108K85	Transcriptional regulator
SB85_09405	ENOG4105GVR	general secretion pathway protein D
SB85_09415	ENOG410678M	general secretion pathway protein M
SB85_09420	ENOG41090VX	general secretion pathway protein L
SB85_09430	ENOG41069G9	General secretion pathway protein J
SB85_09440	ENOG4105WMT	general secretion pathway protein h
SB85_09450	ENOG4105D7Q	type ii secretion system
SB85_09455	ENOG4107QHF	type ii secretion system protein e
SB85_09460	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
SB85_09465	ENOG4105EUR	Domain-Containing protein
SB85_09470	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
SB85_09475	ENOG4105T95	Thiol disulfide interChange protein
SB85_09485	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
SB85_09510	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
SB85_09515	ENOG4105MYG	DNA polymerase iii, chi subunit
SB85_09530	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
SB85_09555	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
SB85_09565	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
SB85_09570	ENOG4105VFQ	Histone family protein nucleoid-structuring protein H-NS
SB85_09585	ENOG4105DHJ	ABC, transporter
SB85_09590	ENOG4108SNX	Mammalian cell entry related domain protein
SB85_09605	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
SB85_09625	ENOG4107QKV	phosphomannomutase
SB85_09635	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
SB85_09640	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
SB85_09655	ENOG4105BZJ	Electron transfer flavoprotein
SB85_09660	ENOG4105C10	Electron transfer flavoprotein
SB85_09695	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
SB85_09725	ENOG4108DMA	Nad-dependent epimerase dehydratase
SB85_09730	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
SB85_09750	ENOG4105C28	cystathionine
SB85_09775	ENOG4105CZX	twitching motility protein
SB85_09780	ENOG4108RXX	maleylacetoacetate isomerase
SB85_09790	ENOG4105C1J	atp-dependent rna helicase
SB85_09795	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
SB85_09820	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
SB85_09825	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
SB85_09830	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
SB85_09835	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
SB85_09850	ENOG4105DGW	oligopeptidase A
SB85_09855	ENOG4105C6T	cysteine synthase
SB85_09865	ENOG4105C59	p-type ATPase
SB85_09870	ENOG4108Z6Z	Transcriptional regulator
SB85_09880	ENOG4105E3B	Multicopper oxidase
SB85_09900	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
SB85_09910	ENOG4105C19	ABC transporter
SB85_09920	ENOG4107RBB	ABC transporter, permease
SB85_09925	ENOG4107RBB	ABC transporter, permease
SB85_09935	ENOG4108EE5	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
SB85_09945	ENOG4107RBB	ABC transporter, permease
SB85_09950	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
SB85_09965	ENOG4107RBB	ABC transporter, permease
SB85_09970	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
SB85_09975	ENOG4105BZU	Histidine kinase
SB85_09985	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
SB85_10000	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
SB85_10005	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
SB85_10010	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
SB85_10015	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
SB85_10020	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
SB85_10025	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
SB85_10030	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
SB85_10035	ENOG4107RAZ	it plays a direct role in the translocation of protons across the membrane (By similarity)
SB85_10055	ENOG4107QN2	dihydrolipoyl dehydrogenase
SB85_10085	ENOG4105D01	(LipO)protein
SB85_10090	ENOG4108UMI	ABC transporter, permease
SB85_10095	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
SB85_10100	ENOG4105DJP	Membrane
SB85_10105	ENOG4108VPT	UPF0234 protein
SB85_10160	ENOG410626B	catechol 1,2-dioxygenase
SB85_10185	ENOG4105I08	Pseudouridine synthase
SB85_10225	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
SB85_10230	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
SB85_10235	ENOG4105EW9	transcriptional regulator AsnC family
SB85_10260	ENOG4107RD7	Flagellar Motor Protein, MotA
SB85_10265	ENOG4105ER2	Ompa motb domain protein
SB85_10290	ENOG4105E3A	(ABC) transporter
SB85_10295	ENOG4105DA5	(ABC) transporter
SB85_10310	ENOG4105EEQ	Na H antiporter
SB85_10330	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
SB85_10340	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
SB85_10345	ENOG4105CC0	LysR family Transcriptional regulator
SB85_10355	ENOG4105EQ2	LysR family Transcriptional regulator
SB85_10360	ENOG4105CPC	Aldo Keto reductase
SB85_10365	ENOG4108048	decarboxylase
SB85_10370	ENOG4108FN7	Aldo keto reductase
SB85_10385	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
SB85_10390	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
SB85_10410	ENOG4105BZU	Histidine kinase
SB85_10435	ENOG4105E0K	tonB-dependent siderophore receptor
SB85_10445	ENOG4108VAC	response regulator
SB85_10450	ENOG4108HRK	Histidine kinase
SB85_10460	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
SB85_10470	ENOG4107QTZ	amino acid
SB85_10490	ENOG4106R7G	Glycoside hydrolase family 5
SB85_10495	ENOG4106R7G	Glycoside hydrolase family 5
SB85_10520	ENOG4105E4C	Lytic transglycosylase catalytic
SB85_10530	ENOG4105F87	Dehydratase
SB85_10540	ENOG4105CF7	AraC family transcriptional regulator
SB85_10550	ENOG4105D7N	magnesium and cobalt transport protein CorA
SB85_10555	ENOG4105C85	amino acid
SB85_10565	ENOG4105DFI	Membrane
SB85_10600	ENOG4107QS8	(LipO)protein
SB85_10610	ENOG4105EYF	MMPL domain protein
SB85_10620	ENOG4108MYR	Secreted protein
SB85_10630	ENOG4105EUP	HipA domain protein
SB85_10760	ENOG4108YYC	ycei family
SB85_10795	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
SB85_10810	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
SB85_10815	ENOG4105CSH	Transporter
SB85_10830	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
SB85_10835	ENOG41082IR	Excinuclease ABC C subunit domain protein
SB85_10840	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
SB85_10860	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
SB85_10865	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
SB85_10870	ENOG4108K8S	endonuclease I
SB85_10875	ENOG4105VF7	tolerance protein
SB85_10880	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
SB85_10885	ENOG4107USA	Thioredoxin
SB85_10895	ENOG4105CPE	K01197 hyaluronoglucosaminidase EC 3.2.1.35
SB85_10900	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
SB85_10905	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
SB85_10915	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
SB85_10930	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
SB85_10945	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
SB85_10950	ENOG4108HPI	phosphatidate Cytidylyltransferase
SB85_10975	ENOG41077RS	Phosphatase
SB85_10980	ENOG4105E8V	Alpha Beta Hydrolase Fold protein
SB85_10985	ENOG4108UMZ	Cdp-alcohol phosphatidyltransferase
SB85_10990	ENOG4105DC1	bifunctional purine biosynthesis protein purh
SB85_11010	ENOG4105EM2	membrane
SB85_11065	ENOG4105E09	nadh pyrophosphatase
SB85_11070	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
SB85_11095	ENOG4105BZU	Histidine kinase
SB85_11100	ENOG4108UQY	Iron-storage protein
SB85_11105	ENOG4105W53	bacterioferritin-associated ferredoxin
SB85_11110	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
SB85_11125	ENOG4108UJD	30S ribosomal protein S9
SB85_11130	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
SB85_11135	ENOG4108S0N	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol (By similarity)
SB85_11145	ENOG4105KPY	Small multidrug resistance protein
SB85_11150	ENOG4105FDS	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
SB85_11155	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
SB85_11160	ENOG410635A	Membrane
SB85_11175	ENOG4105DK0	Indole-3-glycerol phosphate synthase
SB85_11190	ENOG4105DDQ	anthranilate synthase
SB85_11200	ENOG4105C5W	Aldolase
SB85_11205	ENOG4105CRQ	synthase (Component I)
SB85_11210	ENOG4107TE5	Lipid kinase
SB85_11220	ENOG4105DJV	ribulose-phosphate 3-epimerase
SB85_11225	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
SB85_11230	ENOG4105C8V	SAICAR synthetase
SB85_11265	ENOG4105D65	subunit l
SB85_11270	ENOG4108ZE9	Monovalent cation H antiporter subunit C
SB85_11275	ENOG4107R4Z	monovalent cation h antiporter subunit d
SB85_11280	ENOG4105SC1	monovalent cation H antiporter subunit E
SB85_11285	ENOG4105W4C	monovalent cation H antiporter subunit F
SB85_11290	ENOG4105KJM	monovalent cation h antiporter subunit g
SB85_11295	ENOG4105FEU	K -dependent Na -Ca exchanger
SB85_11300	ENOG4107VGR	Catalase
SB85_11315	ENOG4105BZU	Histidine kinase
SB85_11320	ENOG4108S01	response regulator
SB85_11325	ENOG4105BZU	Histidine kinase
SB85_11335	ENOG4108M15	ABC transporter
SB85_11340	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
SB85_11350	ENOG4105C19	ABC transporter
SB85_11355	ENOG4107RBB	ABC transporter, permease
SB85_11375	ENOG4105FDR	Membrane
SB85_11395	ENOG4105C31	Tryptophanyl-tRNA synthetase
SB85_11405	ENOG4105VDW	Csbd family
SB85_11420	ENOG41066UZ	arginase EC 3.5.3.1
SB85_11470	ENOG4105EB3	Histidine kinase
SB85_11475	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
SB85_11485	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
SB85_11505	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
SB85_11510	ENOG4105BZS	acriflavin resistance protein
SB85_11520	ENOG4105EB3	Histidine kinase
SB85_11525	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
SB85_11540	ENOG4106KE4	Dehydrogenase
SB85_11545	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
SB85_11560	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
SB85_11570	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
SB85_11590	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
SB85_11595	ENOG4109025	Glyoxalase Bleomycin resistance protein (Dioxygenase
SB85_11600	ENOG4105D94	Major Facilitator Superfamily
SB85_11605	ENOG4106NZI	LysR family Transcriptional regulator
SB85_11615	ENOG4105K63	Thioredoxin
SB85_11625	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
SB85_11630	ENOG4107QYD	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
SB85_11640	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
SB85_11660	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
SB85_11665	ENOG4108ZHJ	Organic hydroperoxide resistance protein
SB85_11670	ENOG4105K56	Transcriptional regulator
SB85_11680	ENOG4105D6Z	AFG1 family ATPase
SB85_11690	ENOG4108TZV	Membrane
SB85_11695	ENOG4105CKI	cobalamin synthesis protein
SB85_11725	ENOG4105C1G	acyl-Coa dehydrogenase
SB85_11730	ENOG4107QX3	carboxylase
SB85_11770	ENOG4105CD5	CoA-binding domain protein
SB85_11775	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
SB85_11780	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
SB85_11785	ENOG4105BZP	glycoside hydrolase 15-related
SB85_11790	ENOG4105ETX	regulatoR
SB85_11805	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
SB85_11815	ENOG4105VNG	YcgL domain-containing protein
SB85_11820	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
SB85_11830	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
SB85_11845	ENOG4105C2D	reductase
SB85_11870	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
SB85_11885	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
SB85_11900	ENOG4108VX5	3-methyladenine DNA glycosylase
SB85_11910	ENOG4105MA0	exported protein
SB85_11915	ENOG4105CFU	surface antigen
SB85_11930	ENOG4108YXG	UPF0502 protein
SB85_11950	ENOG4105CUR	5'-nucleotidase, lipoprotein e(p4) family
SB85_11955	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
SB85_11975	ENOG4105ETE	Transcriptional regulator (LacI family
SB85_11990	ENOG4105E55	glycerol-3-phosphate acyltransferase
SB85_12055	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
SB85_12075	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
SB85_12080	ENOG4105DH7	May be involved in recombination (By similarity)
SB85_12090	ENOG4105C8Q	Methyl-accepting chemotaxis
SB85_12100	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
SB85_12115	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
SB85_12120	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
SB85_12130	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
SB85_12135	ENOG4107QHF	type ii secretion system protein e
SB85_12140	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
SB85_12145	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
SB85_12150	ENOG4107RDJ	Sulfotransferase
SB85_12160	ENOG4105C4R	Atp-dependent dna helicase
SB85_12170	ENOG4107104	thymidine kinase
SB85_12175	ENOG4105WG9	Conserved Protein
SB85_12180	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
SB85_12190	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
SB85_12195	ENOG4105C4M	(Ubiquinol oxidase) subunit I
SB85_12215	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
SB85_12225	ENOG4105C2M	dna polymerase I
SB85_12235	ENOG4107YZX	Universal stress protein
SB85_12255	ENOG4105X23	Endonuclease Exonuclease phosphatase
SB85_12260	ENOG4105DZQ	phospholipase D Transphosphatidylase
SB85_12265	ENOG4107UXM	Membrane
SB85_12280	ENOG4105C4R	Atp-dependent dna helicase
SB85_12285	ENOG4105HEI	LysR family (Transcriptional regulator
SB85_12290	ENOG4105C57	major facilitator superfamily
SB85_12300	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
SB85_12305	ENOG4105W0E	50S ribosomal protein L33
SB85_12310	ENOG4105KDC	50s ribosomal protein l28
SB85_12350	ENOG4105CKK	Glycosyl transferase, family 2
SB85_12375	ENOG4107QJE	Chromosome Partitioning Protein
SB85_12380	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
SB85_12410	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
SB85_12420	ENOG4107RGH	Aldehyde dehydrogenase
SB85_12425	ENOG4105PAD	Hydrolase
SB85_12430	ENOG4107QN1	sodium solute
SB85_12445	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
SB85_12455	ENOG4105WPN	DNA integration recombination invertion protein
SB85_12460	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
SB85_12465	ENOG4105CGU	Enoyl-CoA hydratase
SB85_12470	ENOG4105E39	Enoyl-CoA hydratase
SB85_12475	ENOG4105C1G	acyl-Coa dehydrogenase
SB85_12480	ENOG4105C26	Dehydrogenase
SB85_12485	ENOG4108UI1	Probably functions as a manganese efflux pump (By similarity)
SB85_12500	ENOG4107RDJ	Sulfotransferase
SB85_12505	ENOG4105BZU	Histidine kinase
SB85_12510	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
SB85_12515	ENOG4105DJ9	glucan biosynthesis protein
SB85_12520	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
SB85_12535	ENOG4105DKW	ABC transporter
SB85_12540	ENOG4105KVH	Transcriptional regulator
SB85_12560	ENOG4105C4R	Atp-dependent dna helicase
SB85_12565	ENOG4108I5C	dEAD DEAH box helicase
SB85_12595	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
SB85_12605	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
SB85_12610	ENOG41067YR	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
SB85_12625	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
SB85_12635	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
SB85_12640	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
SB85_12645	ENOG4108TYN	CAAX amino terminal protease family protein
SB85_12650	ENOG4108K0D	peptidase, M48
SB85_12685	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
SB85_12695	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
SB85_12730	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
SB85_12735	ENOG4105CGF	Aromatic amino acid aminotransferase
SB85_12740	ENOG4105CHB	tonB-dependent Receptor
SB85_12745	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
SB85_12750	ENOG4105C26	Dehydrogenase
SB85_12790	ENOG4105DMF	Dehydrogenase
SB85_12795	ENOG41073TP	transcriptional regulator
SB85_12810	ENOG4105BZU	Histidine kinase
SB85_12815	ENOG4105WH1	Two component transcriptional regulator luxr family
SB85_12820	ENOG4105RKW	reductase (By
SB85_12890	ENOG4105CMM	transposase
SB85_12960	ENOG4107ZSV	Receptor
SB85_12965	ENOG4107RBR	Receptor
SB85_12990	ENOG4105EBR	Carboxylesterase
SB85_13005	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
SB85_13015	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
SB85_13020	ENOG4105ETE	Transcriptional regulator (LacI family
SB85_13030	ENOG4105D50	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate (By similarity)
SB85_13035	ENOG4105CHR	reductase
SB85_13045	ENOG4106B0W	Curli production assembly transport component CsgG
SB85_13065	ENOG4108YXU	transcriptional regulator AsnC family
SB85_13070	ENOG4105CNM	Receptor
SB85_13085	ENOG4105D78	K07001 NTE family protein
SB85_13105	ENOG4105C8Q	Methyl-accepting chemotaxis
SB85_13110	ENOG4105SBG	acid phosphatase
SB85_13120	ENOG4105DU1	integral membrane protein, terc
SB85_13125	ENOG4105DR4	Methyltransferase
SB85_13155	ENOG4105CUB	amino acid
SB85_13160	ENOG4108ZXC	Two component transcriptional regulator, luxr family
SB85_13165	ENOG4105BZU	Histidine kinase
SB85_13180	ENOG4107QSV	RmuC domain protein
SB85_13185	ENOG4108V06	Glutathione peroxidase
SB85_13190	ENOG410903C	(LipO)protein
SB85_13205	ENOG4107PE3	Mammalian cell entry related domain protein
SB85_13210	ENOG4105CY3	ABC transporter, permease
SB85_13215	ENOG4105DHJ	ABC, transporter
SB85_13250	ENOG4105DSY	exodeoxyribonuclease V, gamma
SB85_13255	ENOG4107QKA	exodeoxyribonuclease V beta
SB85_13260	ENOG4107QYX	exodeoxyribonuclease v alpha
SB85_13275	ENOG4105VDM	plasmid maintenance system antidote protein, xre family
SB85_13305	ENOG4105C8Q	Methyl-accepting chemotaxis
SB85_13315	ENOG4105CSH	Transporter
SB85_13320	ENOG4105EUJ	GTP cyclohydrolase i
SB85_13345	ENOG4105K5B	UPF0225 protein
SB85_13350	ENOG4105CVE	Lytic murein transglycosylase
SB85_13370	ENOG4105DKK	Benzoate
SB85_13410	ENOG4108Z5K	methylglyoxal synthase
SB85_13435	ENOG4105BZ8	glutamate synthase
SB85_13440	ENOG4105CBC	glutamate synthase
SB85_13465	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
SB85_13470	ENOG4105DQE	DNA ligase
SB85_13495	ENOG4108I5C	dEAD DEAH box helicase
SB85_13550	ENOG4105C54	Major Facilitator superfamily
SB85_13600	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
SB85_13605	ENOG4107QJE	Chromosome Partitioning Protein
SB85_13610	ENOG4105M4E	phosphohistidine phosphatase, SixA
SB85_13620	ENOG4107RZC	phospholipase d
SB85_13625	ENOG4105KA0	thioesterase Superfamily protein
SB85_13650	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
SB85_13655	ENOG4105C5F	glutamine synthetase
SB85_13670	ENOG4105BZU	Histidine kinase
SB85_13675	ENOG4105CUX	Signal transduction histidine kinase
SB85_13680	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
SB85_13685	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
SB85_13690	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
SB85_13705	ENOG4105CHU	acetyl-coa acetyltransferase
SB85_13730	ENOG4105SUU	thioesterase domain
SB85_13745	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
SB85_13750	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
SB85_13760	ENOG4108RFG	Tetr family transcriptional regulator
SB85_13770	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
SB85_13790	ENOG4105E2T	synthase III
SB85_13795	ENOG4107R3N	Filamentation induced by cAMP protein fic
SB85_13805	ENOG4108J2P	Alpha beta hydrolase fold
SB85_13815	ENOG4105PI0	Ferredoxin
SB85_13820	ENOG410680H	amp-dependent synthetase and ligase
SB85_13825	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
SB85_13840	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
SB85_13850	ENOG4105DR9	pseudouridine synthase
SB85_13860	ENOG4108YZN	class I peptide chain release factor
SB85_13880	ENOG4105EMN	RNA polymerase sigma factor
SB85_13885	ENOG4105D44	asparaginase
SB85_13925	ENOG4105DUM	transcriptional regulator, lysR family
SB85_13930	ENOG4107QP3	malate synthase g
SB85_13940	ENOG4105BZU	Histidine kinase
SB85_13995	ENOG4105Q95	Cupin 2, conserved barrel domain protein
SB85_14000	ENOG4105CHH	sulfate transporter
SB85_14030	ENOG4108D7R	p-hydroxycinnamoyl CoA hydratase lyase
SB85_14035	ENOG4108IQE	Amp-dependent synthetase and ligase
SB85_14045	ENOG4105DNH	Major Facilitator
SB85_14075	ENOG41072AC	4-hydroxybenzoate 3-monooxygenase
SB85_14105	ENOG4107QNJ	CoA-transferase subunit B
SB85_14110	ENOG4105CHU	acetyl-coa acetyltransferase
SB85_14120	ENOG4105EU7	Protocatechuate 3,4-dioxygenase, beta
SB85_14125	ENOG4107RAW	3-carboxy-cis-cis-muconate cycloisomerase
SB85_14130	ENOG4105F2Z	3-oxoadipate enol-lactonase
SB85_14135	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
SB85_14140	ENOG4107YPT	transcriptional regulator
SB85_14170	ENOG4108R99	pseudouridine synthase
SB85_14180	ENOG4105CQ7	ATP-dependent helicase
SB85_14185	ENOG4105F8V	Hydrolase, tatD family
SB85_14275	ENOG4105E3A	(ABC) transporter
SB85_14280	ENOG4105DA5	(ABC) transporter
SB85_14285	ENOG4108JA0	Oxidoreductase, FAD NAD(P)-binding domain protein
SB85_14295	ENOG4105VZ8	Transcriptional regulator
SB85_14305	ENOG4108IUW	ABC transporter
SB85_14325	ENOG4108TEB	UPF0114 protein
SB85_14330	ENOG4105CYM	Glutathione S-transferase
SB85_14365	ENOG4105D52	delta-aminolevulinic acid dehydratase
SB85_14415	ENOG4105DVT	helicase
SB85_14425	ENOG4105CH6	catalase
SB85_14520	ENOG4105CSH	Transporter
SB85_14535	ENOG4105C02	permease
SB85_14585	ENOG4105F2I	Transposase
SB85_14610	ENOG4106032	Glutathionylspermidine synthase
SB85_14630	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
SB85_14660	ENOG4108Z0R	Transferase
SB85_14665	ENOG4106JPM	3-dehydroshikimate dehydratase
SB85_14670	ENOG4105TW1	Carbohydrate-selective porin OprB
SB85_14675	ENOG4105FF2	Type I DHQase
SB85_14680	ENOG4105D2S	major facilitator superfamily
SB85_14690	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
SB85_14695	ENOG4105BZS	acriflavin resistance protein
SB85_14700	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
SB85_14735	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
SB85_14745	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
SB85_14755	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
SB85_14775	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
SB85_14780	ENOG41081UC	Inherit from COG: Competence protein
SB85_14785	ENOG4105C3D	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
SB85_14790	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
SB85_14800	ENOG4105BZU	Histidine kinase
SB85_14825	ENOG4105C0P	Mg chelatase subunit ChlI
SB85_14830	ENOG4105W0Z	cytoplasmic protein
SB85_14835	ENOG4108YZA	Nitrogen regulatory protein pii
SB85_14850	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
SB85_14855	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
SB85_14865	ENOG4108HRK	Histidine kinase
SB85_14870	ENOG4108NEV	two component transcriptional regulator, LytTR family
SB85_14920	ENOG4105EMU	Dehydrogenase
SB85_14930	ENOG4105C75	arginyL-tRNA synthetase
SB85_14935	ENOG4105W5Q	DNA repair protein (RadC
SB85_14940	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
SB85_14950	ENOG4107QKV	phosphomannomutase
SB85_14960	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
SB85_14965	ENOG4105CGK	Exodeoxyribonuclease III
SB85_14970	ENOG4105EYM	Major Facilitator superfamily
SB85_14980	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
SB85_14985	ENOG4105DR5	peptidase
SB85_14990	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
SB85_15020	ENOG4105DQ4	alcohol dehydrogenase
SB85_15025	ENOG4107VAM	peptidase, m28
SB85_15035	ENOG41063SB	peptidase
SB85_15040	ENOG4105CN1	protease
SB85_15045	ENOG4105C5I	Dehydrogenase
SB85_15060	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
SB85_15070	ENOG4105C26	Dehydrogenase
SB85_15090	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
SB85_15095	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
SB85_15120	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
SB85_15125	ENOG4105C8Q	Methyl-accepting chemotaxis
SB85_15135	ENOG4105DHU	Bile acid
SB85_15145	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
SB85_15150	ENOG4107S2Z	UPF0761 membrane protein
SB85_15160	ENOG4105VCC	30S ribosomal protein S21
SB85_15165	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
SB85_15170	ENOG4107ZVW	dihydroneopterin aldolase
SB85_15175	ENOG4105CUY	Mechanosensitive ion channel
SB85_15190	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
SB85_15195	ENOG4108Z12	YiaAB two helix domain-containing protein
SB85_15220	ENOG4105D5Q	Arginine ornithine antiporter
SB85_15230	ENOG4105ETE	Transcriptional regulator (LacI family
SB85_15255	ENOG4105CMG	Carbohydrate kinase
SB85_15260	ENOG4105C93	Xylose Isomerase
SB85_15270	ENOG4105ETE	Transcriptional regulator (LacI family
SB85_15275	ENOG4105D0H	Alpha-glucuronidase (EC 3.2.1.139)
SB85_15295	ENOG4105DT9	hydrolase family 43
SB85_15300	ENOG4105DTQ	mandelate racemase muconate lactonizing
SB85_15315	ENOG4105D05	Receptor
SB85_15320	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
SB85_15380	ENOG4105E32	cytoplasmic protein
SB85_15385	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
SB85_15390	ENOG4107URF	beta-phospho-glucomutase
SB85_15395	ENOG4105C02	permease
SB85_15415	ENOG4105C0H	protease
SB85_15420	ENOG4105CDU	Replicative dna helicase
SB85_15445	ENOG4105BZU	Histidine kinase
SB85_15450	ENOG4108RU0	short-chain dehydrogenase reductase
SB85_15480	ENOG4105CGK	Exodeoxyribonuclease III
SB85_15485	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
SB85_15490	ENOG4108W15	Protein of unknown function (DUF1456)
SB85_15500	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
SB85_15520	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
SB85_15540	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
SB85_15545	ENOG4105ERH	Fumarylacetoacetate hydrolase
SB85_15550	ENOG4105DIA	mandelate racemase muconate lactonizing
SB85_15555	ENOG4105QJH	Domain of unknown function (DUF718)
SB85_15560	ENOG4105EDR	glucose galactose transporter
SB85_15565	ENOG4108K2P	TRANSCRIPTIONal
SB85_15625	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
SB85_15630	ENOG4105EGS	Mechanosensitive ion channel
SB85_15650	ENOG4105CKW	Inner membrane protein yedI
SB85_15655	ENOG4105CKW	Inner membrane protein yedI
SB85_15660	ENOG4105BZU	Histidine kinase
SB85_15675	ENOG4105D7K	pfkb domain protein
SB85_15695	ENOG4105C1J	atp-dependent rna helicase
SB85_15705	ENOG4107QSN	dihydrolipoamide acetyltransferase
SB85_15720	ENOG4107RUY	(E1 component), alpha subunit
SB85_15735	ENOG4105DUX	Transporter
SB85_15755	ENOG4105WDY	DNA (cytosine-5-)-methyltransferase
SB85_15760	ENOG4105F1J	Homogentisate 1,2-dioxygenase
SB85_15780	ENOG4105BZS	acriflavin resistance protein
SB85_15785	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
SB85_15790	ENOG4105CH2	amidohydrolase
SB85_15800	ENOG4109066	lysm domain bon superfamily protein
SB85_15810	ENOG4105CE4	GlcNAc 6-P deacetylase
SB85_15815	ENOG4105E98	transcriptional regulator DeoR family
SB85_15820	ENOG4105C6Q	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
SB85_15825	ENOG4105EZX	Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P (By similarity)
SB85_15830	ENOG4105E70	isomerase
SB85_15845	ENOG4105EPC	oxidoreductase
SB85_15855	ENOG4105E9K	Isocitrate dehydrogenase
SB85_15860	ENOG4105VS7	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity)
SB85_15875	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
SB85_15880	ENOG4105K63	Thioredoxin
SB85_15890	ENOG4105CAK	Cell division ATP-binding protein ftsE
SB85_15895	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
SB85_15900	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
SB85_15905	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
SB85_15910	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
SB85_15915	ENOG4105EN6	Membrane
SB85_15930	ENOG4105C25	Primosomal protein n'
SB85_15940	ENOG4107QI1	Mate efflux family protein
SB85_15945	ENOG4105D07	Signal peptide peptidase, SppA
SB85_15955	ENOG4105CHR	reductase
SB85_15970	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
SB85_15975	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
SB85_15990	ENOG4108RPN	Protein smg homolog
SB85_15995	ENOG4105C79	DNA protecting protein DprA
SB85_16000	ENOG4108WZM	domain protein
SB85_16005	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
SB85_16010	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
SB85_16015	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
SB85_16020	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
SB85_16035	ENOG4106WTF	Glycosyl transferase, family 2
SB85_16055	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
SB85_16060	ENOG4108Z7F	N-acetyltransferase
SB85_16070	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
SB85_16075	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
SB85_16090	ENOG4107P2S	Transcriptional regulator
SB85_16095	ENOG4105CWX	Alpha-1,2-mannosidase
SB85_16100	ENOG4105EP6	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity)
SB85_16105	ENOG4105CG3	alpha amylase, catalytic region
SB85_16110	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
SB85_16155	ENOG4105DAV	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
SB85_16180	ENOG4105ETE	Transcriptional regulator (LacI family
SB85_16195	ENOG4107S1Q	Phosphatase
SB85_16210	ENOG4105BZS	acriflavin resistance protein
SB85_16215	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
SB85_16220	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
SB85_16225	ENOG4105GR3	Histidine kinase
SB85_16235	ENOG4108Q5F	Tetr family transcriptional regulator
SB85_16260	ENOG4105D2S	major facilitator superfamily
SB85_16280	ENOG4105C8Q	Methyl-accepting chemotaxis
SB85_16285	ENOG4105WEF	catalase
SB85_16290	ENOG4108Z9Z	response to DNA damage stimulus
SB85_16295	ENOG4108N8X	transition metal ion binding
SB85_16300	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
SB85_16305	ENOG4105EJ2	Transcriptional regulator
SB85_16310	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
SB85_16335	ENOG4105C7K	acetolactate synthase
SB85_16340	ENOG4105BZU	Histidine kinase
SB85_16345	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
SB85_16365	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
SB85_16380	ENOG4105F2I	Transposase
SB85_16405	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
SB85_16410	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
SB85_16415	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
SB85_16425	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
SB85_16435	ENOG4105GTG	Isochorismatase
SB85_16440	ENOG4105C3A	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity)
SB85_16450	ENOG4108NEV	two component transcriptional regulator, LytTR family
SB85_16455	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
SB85_16470	ENOG4105KVH	Transcriptional regulator
SB85_16505	ENOG4105WD1	Membrane
SB85_16515	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
SB85_16525	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
SB85_16535	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
SB85_16540	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
SB85_16560	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
SB85_16565	ENOG4105CD8	aminopeptidase N
SB85_16570	ENOG4107TTQ	Alpha beta hydrolase fold
SB85_16585	ENOG4105DZG	Dehydrogenase
SB85_16590	ENOG4108Q1J	Extracellular solute-binding protein, family 3
SB85_16615	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
SB85_16635	ENOG4105DFF	Rod shape-determining protein mreb
SB85_16640	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
SB85_16650	ENOG4105CJN	penicillin-binding protein
SB85_16655	ENOG4105CNI	cell division protein FtsW
SB85_16670	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
SB85_16675	ENOG4105W8H	transhydrogenase (subunit alpha
SB85_16680	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
SB85_16685	ENOG4105C26	Dehydrogenase
SB85_16690	ENOG4105CVE	Lytic murein transglycosylase
SB85_16695	ENOG4105K6T	rare lipoprotein A
SB85_16700	ENOG4105DZ1	carboxypeptidase
SB85_16745	ENOG4105CN1	protease
SB85_16755	ENOG4105EGI	Transcriptional regulator
SB85_16800	ENOG4105ECP	epimerase
SB85_16810	ENOG4108J5G	6-phosphogluconate dehydrogenase
SB85_16815	ENOG4105D9R	oxidoreductase
SB85_16820	ENOG4105W4M	Transport-associated protein
SB85_16830	ENOG4105BZU	Histidine kinase
SB85_16840	ENOG4105BZU	Histidine kinase
SB85_16855	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
SB85_16870	ENOG4108YQE	rare lipoprotein a
SB85_16880	ENOG4105FDP	GntR family transcriptional regulator
SB85_16885	ENOG4105EDR	glucose galactose transporter
SB85_16890	ENOG4105ETE	Transcriptional regulator (LacI family
SB85_16895	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
SB85_16900	ENOG4105CE4	GlcNAc 6-P deacetylase
SB85_16910	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
SB85_16935	ENOG4108Z33	Thiol disulfide Interchange Protein
SB85_16940	ENOG4106RE7	Cytochrome
SB85_16945	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
SB85_16955	ENOG4105Z68	AraC Family Transcriptional Regulator
SB85_16960	ENOG4108UYE	Lactoylglutathione lyase
SB85_16975	ENOG4105EB3	Histidine kinase
SB85_16980	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
SB85_16995	ENOG4108QBQ	Catalyzes the condensation of formaldehyde and glutathione to S-hydroxymethylglutathione (By similarity)
SB85_17000	ENOG4105C4W	S-formylglutathione hydrolase
SB85_17005	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
SB85_17010	ENOG4105JAB	phenazine biosynthesis protein, phzf family
SB85_17025	ENOG4108RMV	DegV Family
SB85_17050	ENOG4105CQM	Urea amidohydrolase subunit alpha
SB85_17055	ENOG4105CD3	dihydroorotase
SB85_17090	ENOG4105CHM	Aminotransferase
SB85_17095	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
SB85_17110	ENOG4107QW3	Sucrose phosphorylase
SB85_17125	ENOG4105ETE	Transcriptional regulator (LacI family
SB85_17130	ENOG4105CHR	reductase
SB85_17135	ENOG4105D4T	Citrate transporter
SB85_17150	ENOG4105DHQ	Histidine kinase
SB85_17155	ENOG4106JDA	Phosphoglycerate transport regulatory protein PGTC
SB85_17160	ENOG4105BZU	Histidine kinase
SB85_17180	ENOG4105BZU	Histidine kinase
SB85_17190	ENOG4105CK2	sodium dicarboxylate symporter
SB85_17195	ENOG4105C6K	Malic enzyme
SB85_17215	ENOG4108JJA	ABC, transporter
SB85_17240	ENOG4105NWR	lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase
SB85_17245	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
SB85_17250	ENOG4105DFG	type I secretion outer membrane protein
SB85_17255	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
SB85_17280	ENOG4108W6C	Dehydrogenase
SB85_17290	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
SB85_17295	ENOG4105DHQ	Histidine kinase
SB85_17300	ENOG4105BZU	Histidine kinase
SB85_17305	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
SB85_17325	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
SB85_17330	ENOG4105C7B	Threonine dehydratase
SB85_17345	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
SB85_17350	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
SB85_17360	ENOG4105C8Q	Methyl-accepting chemotaxis
SB85_17375	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
SB85_17395	ENOG4105F0N	pyrophosphate phospho-hydrolase
SB85_17405	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
SB85_17430	ENOG4105DFU	Cell wall formation (By similarity)
SB85_17445	ENOG4108KF1	Membrane
SB85_17470	ENOG4105EYW	Ion transport protein
SB85_17475	ENOG4105C8Y	Acetylornithine aminotransferase
SB85_17485	ENOG41090JD	Blue (Type 1) copper domain protein
SB85_17490	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
SB85_17495	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
SB85_17500	ENOG4105VCQ	rubredoxin
SB85_17515	ENOG4105E66	phosphoriboisomerase A
SB85_17525	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
SB85_17535	ENOG4105W8B	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
SB85_17545	ENOG4105BZU	Histidine kinase
SB85_17555	ENOG4107RAQ	aminopeptidase
SB85_17565	ENOG4105D9Y	Splits dipeptides with a prolyl residue in the C- terminal position (By similarity)
SB85_17575	ENOG4105CSA	Coproporphyrinogen iii oxidase
SB85_17580	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
SB85_17585	ENOG4108ZI4	Glyoxalase Bleomycin resistance protein (Dioxygenase
SB85_17590	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
SB85_17595	ENOG4105DSJ	YicC domain protein
SB85_17605	ENOG4108ZZF	transport protein (ExbD)
SB85_17615	ENOG4105WD1	Membrane
SB85_17620	ENOG4108YNN	Heme oxygenase
SB85_17650	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
SB85_17655	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
SB85_17660	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
SB85_17665	ENOG4105KME	endoribonuclease L-psp
SB85_17670	ENOG4105CB5	ATP-dependent DNA helicase recG
SB85_17680	ENOG4105NRA	50s ribosomal protein l31 type b
SB85_17695	ENOG4108JQC	penicillin-binding protein 1A
SB85_17720	ENOG4105E4G	Type IV pilus
SB85_17725	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
SB85_17755	ENOG4105CK2	sodium dicarboxylate symporter
SB85_17765	ENOG4105CV1	Transketolase (EC 2.2.1.1)
SB85_17820	ENOG4105NA0	Transcriptional regulator
SB85_17840	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
SB85_17845	ENOG4105E0C	molybdate abc transporter
SB85_17850	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
SB85_17860	ENOG41080HT	Transcriptional regulator, arsr family
SB85_17900	ENOG4105EIF	outer membrane protein W
SB85_17905	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
SB85_17920	ENOG4108NVR	Methyl-accepting chemotaxis
SB85_17935	ENOG4105BZA	Phosphoglycerate kinase
SB85_17945	ENOG4105CA9	Pyruvate kinase
SB85_17955	ENOG4107R1Y	fructose-bisphosphate aldolase
SB85_17980	ENOG4108UVJ	appr-1-p processing domain protein
SB85_17995	ENOG4105DU0	nucleoside hydrolase
SB85_18015	ENOG4107R11	Transcriptional regulator
SB85_18025	ENOG4105ES5	Histidine kinase
SB85_18030	ENOG4105K89	arsenate reductase
SB85_18050	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
SB85_18055	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
SB85_18060	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
SB85_18065	ENOG4105C11	sulfate adenylyltransferase), subunit 2
SB85_18070	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
SB85_18075	ENOG4105CD8	aminopeptidase N
SB85_18090	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
SB85_18100	ENOG4105KNA	-acetyltransferase
SB85_18110	ENOG4105C2N	RNA methyltransferase TrmH family group 3
SB85_18125	ENOG4105ETE	Transcriptional regulator (LacI family
SB85_18140	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
SB85_18165	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
SB85_18170	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
SB85_18205	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
SB85_18210	ENOG4105ETX	regulatoR
SB85_18215	ENOG4105BZU	Histidine kinase
SB85_18225	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
SB85_18240	ENOG4107QHF	type ii secretion system protein e
SB85_18245	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
SB85_18250	ENOG4107TUY	Histidine kinase
SB85_18255	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
SB85_18260	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
SB85_18275	ENOG41067HS	methyltransferase
SB85_18280	ENOG4105E46	N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process
SB85_18305	ENOG4108IJ9	(ABC) transporter
SB85_18315	ENOG4105CHC	glucokinase (EC 2.7.1.2)
SB85_18325	ENOG4105C01	Dihydroxy-acid dehydratase
SB85_18340	ENOG4105DRS	transport system, permease
SB85_18350	ENOG4107FKK	extracellular solute-binding protein family 1
SB85_18375	ENOG4105K9H	YciI-like protein
SB85_18380	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
SB85_18385	ENOG4105FE9	pseudouridine synthase
SB85_18405	ENOG4105EUR	Domain-Containing protein
SB85_18410	ENOG4105WH1	Two component transcriptional regulator luxr family
SB85_18435	ENOG4105CHM	Aminotransferase
SB85_18450	ENOG41060IM	Heme exporter protein
SB85_18460	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
SB85_18465	ENOG4105DA4	cytochrome c-type biogenesis protein
SB85_18475	ENOG4105KWW	Biogenesis protein
SB85_18485	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
SB85_18490	ENOG4105DWV	Homoserine O-trans-acetylase
SB85_18500	ENOG4108JJ8	(ABC) transporter
SB85_18505	ENOG4108JJ9	ABC, transporter
SB85_18510	ENOG4105C4M	(Ubiquinol oxidase) subunit I
SB85_18540	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
SB85_18545	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
SB85_18555	ENOG4105CH7	arginosuccinase
SB85_18560	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
SB85_18570	ENOG4105CAS	nag kinase
SB85_18585	ENOG4105CDH	Citrulline--aspartate ligase
SB85_18590	ENOG4105DBV	ornithine carbamoyltransferase
SB85_18605	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
SB85_18630	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
SB85_18640	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
SB85_18665	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
SB85_18670	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
SB85_18675	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
SB85_18695	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
SB85_18700	ENOG4105BZU	Histidine kinase
SB85_18720	ENOG4105C8Q	Methyl-accepting chemotaxis
SB85_18725	ENOG4107QT7	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
SB85_18730	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
SB85_18735	ENOG4105VIE	preprotein translocase, subunit YajC
SB85_18745	ENOG4105BZ1	(ABC) transporter
SB85_18765	ENOG4105CAX	The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity)
SB85_18775	ENOG4105BZU	Histidine kinase
SB85_18780	ENOG4105FE9	pseudouridine synthase
SB85_18830	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
SB85_18855	ENOG4105UGU	tonB-dependent Receptor
SB85_18870	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
SB85_18875	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
SB85_18880	ENOG4105C7W	Xanthine dehydrogenase
SB85_18885	ENOG41080AZ	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
SB85_18890	ENOG4105XRQ	Xanthine dehydrogenase accessory factor
SB85_18895	ENOG4105T0Z	Conserved Protein
SB85_18905	ENOG4105CKX	Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP
SB85_18910	ENOG4105E0Y	RtcB Protein
SB85_18920	ENOG4105CYB	regulatoR
SB85_18925	ENOG4105MYN	Zinc uptake regulation protein
SB85_18950	ENOG4105CT7	inner membrane cred family protein
SB85_18955	ENOG4105EB3	Histidine kinase
SB85_18960	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
SB85_18965	ENOG4105BZU	Histidine kinase
SB85_18970	ENOG4105D6S	protein involved in catabolism of external DNA
SB85_18975	ENOG4108XI2	Domain of unknown function (DUF1963)
SB85_18985	ENOG4108JA2	transcriptioN-repair coupling factor
SB85_18995	ENOG4105CBS	Chea signal transduction histidine kinase
SB85_19000	ENOG4107U4H	Methyl-accepting chemotaxis
SB85_19005	ENOG4105C8Q	Methyl-accepting chemotaxis
SB85_19010	ENOG4105C8Q	Methyl-accepting chemotaxis
SB85_19015	ENOG4108V3W	Chemotaxis protein, CheW
SB85_19020	ENOG4105BZU	Histidine kinase
SB85_19025	ENOG4105BZU	Histidine kinase
SB85_19030	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
SB85_19040	ENOG4105CT4	transporter
SB85_19050	ENOG4108TSE	Transferase
SB85_19060	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
SB85_19065	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
SB85_19070	ENOG4105EUB	pirin domain protein
SB85_19080	ENOG4105EUB	pirin domain protein
SB85_19085	ENOG4105D22	carbon starvation protein
SB85_19090	ENOG4105VCD	cytoplasmic protein
SB85_19115	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
SB85_19125	ENOG4105DUX	Transporter
SB85_19140	ENOG4105ETE	Transcriptional regulator (LacI family
SB85_19150	ENOG4105EAA	nucleoside
SB85_19195	ENOG4108UUM	single-stranded DNA-binding protein
SB85_19200	ENOG4105EAH	synthase
SB85_19215	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
SB85_19230	ENOG4105CFH	Aspartokinase
SB85_19240	ENOG4105JAB	phenazine biosynthesis protein, phzf family
SB85_19250	ENOG4108Z9K	Osmotically inducible protein
SB85_19265	ENOG4105DR5	peptidase
SB85_19280	ENOG4107R7Y	intracellular protease Pfpi family
SB85_19300	ENOG4105C3K	feS assembly ATPase SufC
SB85_19305	ENOG4105JRK	feS assembly protein SufD
SB85_19310	ENOG4105C9B	Cysteine desulfurase
SB85_19320	ENOG4105VQD	rieske 2fe-2S domain-containing protein
SB85_19325	ENOG4108ESX	Receptor
SB85_19340	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
SB85_19365	ENOG4105EHM	Aminoglycoside phosphotransferase
SB85_19370	ENOG4108S0S	Nucleotidyl transferase
SB85_19380	ENOG4105C02	permease
SB85_19390	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
SB85_19405	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
SB85_19425	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
SB85_19435	ENOG4105C2X	Arabinose 5-phosphate isomerase
SB85_19440	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
SB85_19455	ENOG4108IUZ	ABC transporter
SB85_19460	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
SB85_19465	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
SB85_19470	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
SB85_19475	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
SB85_19480	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
SB85_19490	ENOG41080Z8	PHOSPHOCARRIER protein
SB85_19495	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
SB85_19500	ENOG4105CJW	magnesium transporter
SB85_19520	ENOG4108J9M	Transporter
SB85_19525	ENOG4105C85	amino acid
SB85_19535	ENOG4105C8Q	Methyl-accepting chemotaxis
SB85_19540	ENOG4105C8Q	Methyl-accepting chemotaxis
SB85_19545	ENOG4108NFF	pectate lyase
SB85_19555	ENOG4105CXT	aspartate transcarbamylase
SB85_19560	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
SB85_19565	ENOG4108UJU	UPF0301 protein
SB85_19575	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
SB85_19590	ENOG4105W5Z	
SB85_19625	ENOG4105CZX	twitching motility protein
SB85_19630	ENOG4105CZX	twitching motility protein
SB85_19635	ENOG4105DFA	alanine racemase domain protein
SB85_19645	ENOG4105II7	pyrroline-5-carboxylate reductase
SB85_19660	ENOG4108Z4X	TRANSCRIPTIONal
SB85_19665	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
SB85_19675	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
SB85_19680	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
SB85_19685	ENOG4105D49	3-dehydroquinate synthase
SB85_19695	ENOG4105BZS	acriflavin resistance protein
SB85_19700	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
SB85_19715	ENOG4105T16	Transcriptional regulator (AraC family)
SB85_19725	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
SB85_19740	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
SB85_19755	ENOG4108YYC	ycei family
SB85_19790	ENOG4105EWI	Short-chain dehydrogenase reductase Sdr
SB85_19800	ENOG4105F52	Transcriptional regulator
SB85_19835	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
SB85_19840	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
SB85_19845	ENOG4105Y3E	Modulates RecA activity (By similarity)
SB85_19850	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
SB85_19855	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
SB85_19860	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
SB85_19865	ENOG4107TH8	cina domain protein
SB85_19870	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
SB85_19875	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
SB85_19880	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
SB85_19890	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
SB85_19895	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
SB85_19900	ENOG4105HBR	Rna-binding protein
SB85_19910	ENOG4108K5P	(LipO)protein
SB85_19915	ENOG4108UM1	dedA family
SB85_19920	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
SB85_19925	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
SB85_19940	ENOG4108SF5	RNA Polymerase
SB85_19955	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
SB85_19960	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
SB85_19965	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
SB85_19970	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
SB85_19975	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
SB85_19985	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
SB85_19995	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
SB85_20005	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
SB85_20010	ENOG4105EAF	CDP-diacylglycerol pyrophosphatase (EC 3.6.1.26)
SB85_20020	ENOG4105CJ3	phosphate transporter
SB85_20045	ENOG4105DEN	Luciferase family
SB85_20050	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
SB85_20055	ENOG4105C72	UPF0176 protein
SB85_20065	ENOG4108V1T	peptidylprolyl cis-trans isomerase
SB85_20080	ENOG4105BZU	Histidine kinase
SB85_20090	ENOG4105CBC	glutamate synthase
SB85_20095	ENOG4107QQG	Dehydrogenase
SB85_20105	ENOG4105ETE	Transcriptional regulator (LacI family
SB85_20110	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
SB85_20115	ENOG4105DE4	1-phosphofructokinase
SB85_20120	ENOG4105DM4	PTS System
SB85_20150	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
SB85_20190	ENOG4105J3Q	acyl carrier protein
SB85_20200	ENOG4108JPW	Aminotransferase
SB85_20205	ENOG4105JAS	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene) (By similarity)
SB85_20220	ENOG4105D4P	Coproporphyrinogen iii oxidase
SB85_20235	ENOG4105C58	cytochrome c oxidase accessory protein ccog
SB85_20315	ENOG4105NRM	Membrane
SB85_20320	ENOG4105E0K	tonB-dependent siderophore receptor
SB85_20335	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
SB85_20380	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
SB85_20395	ENOG4105CMR	udp-glucose 4-epimerase
SB85_20400	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
SB85_20410	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
SB85_20415	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
SB85_20440	ENOG4105BZ1	(ABC) transporter
SB85_20445	ENOG4105M15	transport protein ExbD
SB85_20455	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
SB85_20465	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
SB85_20470	ENOG4105D60	lipoprotein releasing system transmembrane protein
SB85_20480	ENOG410681N	tpr repeat protein
SB85_20485	ENOG4105E33	succinate dehydrogenase
SB85_20500	ENOG410612Q	succinate dehydrogenase (cytochrome b-556 subunit)