locus-tag	class	description
NUG20_00010	COG0592	DNA-directed DNA polymerase activity
NUG20_00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NUG20_00020	COG0187	DNA topoisomerase II activity
NUG20_00025	COG1266	CAAX protease self-immunity
NUG20_00085	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NUG20_00140	COG4772	TonB-dependent receptor
NUG20_00155	COG3284	Transcriptional regulator
NUG20_00160	COG1012	belongs to the aldehyde dehydrogenase family
NUG20_00205	COG1304	FMN binding
NUG20_00210	COG2186	Transcriptional regulator
NUG20_00215	COG1755	Isoprenylcysteine carboxyl methyltransferase
NUG20_00220	COG4585	Histidine kinase
NUG20_00225	COG2197	response regulator
NUG20_00235	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NUG20_00415	COG4771	TonB-dependent receptor
NUG20_00430	COG1435	thymidine kinase activity
NUG20_00435	COG0210	DNA helicase
NUG20_00450	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NUG20_00460	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NUG20_00460	COG0519	Catalyzes the synthesis of GMP from XMP
NUG20_00475	COG0805	protein transport
NUG20_00485	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NUG20_00495	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
NUG20_00515	COG0037	tRNA processing
NUG20_00520	COG2115	Belongs to the xylose isomerase family
NUG20_00530	COG3661	Belongs to the glycosyl hydrolase 67 family
NUG20_00540	COG4948	Mandelate Racemase Muconate Lactonizing
NUG20_00550	COG1472	Belongs to the glycosyl hydrolase 3 family
NUG20_00555	COG0246	Mannitol dehydrogenase
NUG20_00580	COG0251	oxidation-reduction process
NUG20_00625	COG0583	DNA-binding transcription factor activity
NUG20_00630	COG0667	Aldo Keto reductase
NUG20_00640	COG3386	PFAM SMP-30 Gluconolaconase
NUG20_00665	COG3250	beta-galactosidase activity
NUG20_00670	COG1904	glucuronate isomerase
NUG20_00685	COG2211	Major facilitator Superfamily
NUG20_00710	COG2937	Belongs to the GPAT DAPAT family
NUG20_00740	COG0284	orotidine-5'-phosphate decarboxylase activity
NUG20_00745	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
NUG20_00785	COG3132	Protein of unknown function, DUF480
NUG20_00800	COG0729	surface antigen
NUG20_00805	COG2911	Protein conserved in bacteria
NUG20_00825	COG3209	COG3209 Rhs family protein
NUG20_00850	COG2155	Conserved Protein
NUG20_00855	COG3265	gluconokinase activity
NUG20_00860	COG2211	Major facilitator Superfamily
NUG20_00865	COG3459	Glycosyltransferase 36 associated
NUG20_00870	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NUG20_00875	COG3706	GGDEF domain
NUG20_00885	COG2205	protein histidine kinase activity
NUG20_00890	COG0457	Tetratricopeptide repeat
NUG20_00905	COG1971	Probably functions as a manganese efflux pump
NUG20_00925	COG0477	Major facilitator Superfamily
NUG20_00930	COG1011	Hydrolase
NUG20_00955	COG2091	lysine biosynthetic process via aminoadipic acid
NUG20_00960	COG0357	Ribosomal RNA small subunit methyltransferase G
NUG20_00965	COG1192	Involved in chromosome partitioning
NUG20_00970	COG1475	DNA binding
NUG20_00980	COG0463	Glycosyl transferase, family 2
NUG20_01040	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NUG20_01050	COG0477	Major facilitator Superfamily
NUG20_01060	COG0210	DNA helicase
NUG20_01070	COG0392	lysyltransferase activity
NUG20_01075	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NUG20_01080	COG3568	Endonuclease Exonuclease Phosphatase
NUG20_01110	COG0589	response to stress
NUG20_01235	COG0631	protein serine/threonine phosphatase activity
NUG20_01240	COG0515	serine threonine protein kinase
NUG20_01275	COG2323	membrane
NUG20_01285	COG0408	coproporphyrinogen oxidase activity
NUG20_01305	COG1271	oxidase subunit
NUG20_01310	COG1294	oxidase, subunit
NUG20_01330	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NUG20_01345	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NUG20_01390	COG1028	Short-chain dehydrogenase reductase Sdr
NUG20_01410	COG0463	Glycosyl transferase, family 2
NUG20_01420	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NUG20_01425	COG3100	YcgL domain-containing protein
NUG20_01435	COG1404	Belongs to the peptidase S8 family
NUG20_01450	COG0745	RESPONSE REGULATOR receiver
NUG20_01455	COG3387	PFAM Glycoside hydrolase 15-related
NUG20_01460	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NUG20_01510	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NUG20_01515	COG1960	acyl-CoA dehydrogenase activity
NUG20_01525	COG3245	cytochrome
NUG20_01540	COG0523	cobalamin synthesis protein
NUG20_01545	COG0697	spore germination
NUG20_01555	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
NUG20_01560	COG1846	Transcriptional regulator
NUG20_01565	COG1764	response to oxidative stress
NUG20_01570	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
NUG20_01600	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NUG20_01605	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NUG20_01625	COG0583	DNA-binding transcription factor activity
NUG20_01630	COG2814	Major facilitator Superfamily
NUG20_01645	COG1902	pentaerythritol trinitrate reductase activity
NUG20_01650	COG2084	Dehydrogenase
NUG20_01665	COG0745	RESPONSE REGULATOR receiver
NUG20_01670	COG2205	protein histidine kinase activity
NUG20_01675	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NUG20_01705	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NUG20_01735	COG3228	Belongs to the MtfA family
NUG20_01745	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
NUG20_01745	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
NUG20_01750	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
NUG20_01780	COG3237	CsbD-like
NUG20_01790	COG0180	Tryptophanyl-tRNA synthetase
NUG20_01805	COG0697	spore germination
NUG20_01825	COG0577	efflux transmembrane transporter activity
NUG20_01830	COG1136	(ABC) transporter
NUG20_01835	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NUG20_01840	COG1131	(ABC) transporter
NUG20_01850	COG4585	Histidine kinase
NUG20_01855	COG2197	response regulator
NUG20_01870	COG0753	catalase activity
NUG20_01885	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NUG20_01890	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NUG20_01895	COG0628	permease
NUG20_01920	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NUG20_01950	COG0784	Response regulator, receiver
NUG20_01950	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NUG20_01980	COG4221	oxidoreductase activity
NUG20_01985	COG1028	Short-chain dehydrogenase reductase Sdr
NUG20_01990	COG0583	DNA-binding transcription factor activity
NUG20_02030	COG4773	Receptor
NUG20_02035	COG5507	3-demethylubiquinone-9 3-methyltransferase
NUG20_02050	COG0708	Exodeoxyribonuclease III
NUG20_02060	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NUG20_02065	COG1418	mRNA catabolic process
NUG20_02075	COG4807	Protein conserved in bacteria
NUG20_02090	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
NUG20_02105	COG0840	transmembrane signaling receptor activity
NUG20_02135	COG1028	Short-chain dehydrogenase reductase Sdr
NUG20_02140	COG0179	Fumarylacetoacetate (FAA) hydrolase
NUG20_02145	COG4948	Mandelate Racemase Muconate Lactonizing
NUG20_02150	COG3254	rhamnose metabolic process
NUG20_02155	COG0738	Major facilitator superfamily
NUG20_02200	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
NUG20_02215	COG1802	Transcriptional regulator
NUG20_02235	COG0604	alcohol dehydrogenase
NUG20_02235	COG1028	Short-chain dehydrogenase reductase Sdr
NUG20_02235	COG3321	synthase
NUG20_02240	COG1196	nuclear chromosome segregation
NUG20_02240	COG3264	Mechanosensitive ion channel
NUG20_02245	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
NUG20_02260	COG2354	Protein conserved in bacteria
NUG20_02275	COG0702	epimerase
NUG20_02285	COG1028	Short-chain dehydrogenase reductase Sdr
NUG20_02295	COG0513	Belongs to the DEAD box helicase family
NUG20_02300	COG3227	Zinc metalloprotease (Elastase)
NUG20_02325	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
NUG20_02335	COG3483	tryptophan 2,3-dioxygenase activity
NUG20_02340	COG3104	oligopeptide transport
NUG20_02360	COG2852	Protein conserved in bacteria
NUG20_02385	COG1320	monovalent cation:proton antiporter activity
NUG20_02390	COG2212	antiporter activity
NUG20_02395	COG1863	multisubunit Na H antiporter MnhE subunit
NUG20_02400	COG0651	ATP synthesis coupled electron transport
NUG20_02405	COG1006	Multisubunit Na H antiporter MnhC subunit
NUG20_02410	COG2111	Na H antiporter
NUG20_02410	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NUG20_02415	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NUG20_02440	COG0484	heat shock protein binding
NUG20_02455	COG1597	lipid kinase activity
NUG20_02485	COG4948	Mandelate Racemase Muconate Lactonizing
NUG20_02490	COG3104	oligopeptide transport
NUG20_02495	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
NUG20_02500	COG4771	TonB-dependent receptor
NUG20_02510	COG3949	Membrane
NUG20_02515	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NUG20_02530	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NUG20_02540	COG0134	indole-3-glycerol-phosphate synthase activity
NUG20_02550	COG0730	response to heat
NUG20_02555	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NUG20_02560	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
NUG20_02575	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
NUG20_02600	COG1051	belongs to the nudix hydrolase family
NUG20_02605	COG2906	2 iron, 2 sulfur cluster binding
NUG20_02645	COG2816	NAD+ diphosphatase activity
NUG20_02690	COG2814	Major facilitator Superfamily
NUG20_02695	COG1289	transmembrane transporter activity
NUG20_02715	COG0151	Belongs to the GarS family
NUG20_02725	COG0138	bifunctional purine biosynthesis protein purh
NUG20_02730	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NUG20_02735	COG2267	carboxylic ester hydrolase activity
NUG20_02740	COG0671	phosphoesterase, PA-phosphatase related
NUG20_02740	COG2453	phosphatase
NUG20_02765	COG4589	Belongs to the CDS family
NUG20_02770	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
NUG20_02790	COG2264	protein methyltransferase activity
NUG20_02805	COG0300	oxidoreductase activity
NUG20_02815	COG0439	Biotin carboxylase
NUG20_02820	COG0511	ligase activity, forming carbon-carbon bonds
NUG20_02825	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
NUG20_02830	COG1733	regulation of RNA biosynthetic process
NUG20_02835	COG0625	glutathione transferase activity
NUG20_02855	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NUG20_02865	COG1324	tolerance protein
NUG20_02870	COG2356	endonuclease I
NUG20_02880	COG0459	protein refolding
NUG20_02885	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NUG20_02905	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
NUG20_02920	COG0584	glycerophosphoryl diester phosphodiesterase
NUG20_02965	COG0840	transmembrane signaling receptor activity
NUG20_03030	COG1309	transcriptional regulator
NUG20_03125	COG5520	Belongs to the glycosyl hydrolase 30 family
NUG20_03135	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NUG20_03140	COG2409	Drug exporters of the RND superfamily
NUG20_03165	COG0583	DNA-binding transcription factor activity
NUG20_03185	COG0697	spore germination
NUG20_03190	COG0598	Magnesium transport protein CorA
NUG20_03200	COG2207	Transcriptional regulator
NUG20_03225	COG0741	lytic transglycosylase activity
NUG20_03250	COG0612	Peptidase, M16
NUG20_03270	COG0531	amino acid
NUG20_03280	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
NUG20_03295	COG3275	phosphorelay sensor kinase activity
NUG20_03330	COG5001	Diguanylate cyclase
NUG20_03355	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NUG20_03360	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NUG20_03375	COG0667	Aldo Keto reductase
NUG20_03380	COG0667	Aldo Keto reductase
NUG20_03395	COG0583	DNA-binding transcription factor activity
NUG20_03400	COG3384	dioxygenase
NUG20_03415	COG1573	uracil-dna glycosylase
NUG20_03420	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
NUG20_03430	COG0025	NhaP-type Na H and K H
NUG20_03435	COG1131	(ABC) transporter
NUG20_03440	COG0842	Transport permease protein
NUG20_03515	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NUG20_03570	COG1187	pseudouridine synthase activity
NUG20_03580	COG1666	GTP binding
NUG20_03585	COG0697	spore germination
NUG20_03590	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NUG20_03625	COG0508	dehydrogenase complex catalyzes the overall conversion of
NUG20_03630	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NUG20_03650	COG0356	it plays a direct role in the translocation of protons across the membrane
NUG20_03660	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NUG20_03670	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NUG20_03690	COG0355	proton-transporting ATP synthase activity, rotational mechanism
NUG20_03705	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NUG20_03730	COG0577	efflux transmembrane transporter activity
NUG20_03740	COG1136	(ABC) transporter
NUG20_03740	COG0577	efflux transmembrane transporter activity
NUG20_03745	COG0577	efflux transmembrane transporter activity
NUG20_03745	COG1136	(ABC) transporter
NUG20_03750	COG1136	(ABC) transporter
NUG20_03760	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
NUG20_03785	COG2132	Multicopper oxidase
NUG20_03800	COG2217	Heavy metal translocating P-type atpase
NUG20_03810	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NUG20_03815	COG0339	signal peptide processing
NUG20_03830	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NUG20_03835	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NUG20_03855	COG0546	phosphoglycolate phosphatase activity
NUG20_03865	COG4206	TonB-dependent receptor
NUG20_03875	COG1956	GAF domain-containing protein
NUG20_03880	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
NUG20_03890	COG0720	synthase
NUG20_03895	COG4771	TonB-dependent receptor
NUG20_03915	COG0625	glutathione transferase activity
NUG20_03945	COG0626	cystathionine gamma-synthase activity
NUG20_03970	COG0438	transferase activity, transferring glycosyl groups
NUG20_03975	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
NUG20_03980	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NUG20_03985	COG2813	Specifically methylates the guanine in position
NUG20_04005	COG0463	Glycosyl transferase, family 2
NUG20_04020	COG2086	electron transfer activity
NUG20_04045	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
NUG20_04045	COG0662	Cupin 2, conserved barrel domain protein
NUG20_04050	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NUG20_04070	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
NUG20_04070	COG0644	oxidoreductase
NUG20_04090	COG3218	ABC-type transport auxiliary lipoprotein component
NUG20_04090	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
NUG20_04095	COG1127	ABC transporter
NUG20_04100	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
NUG20_04115	COG0442	prolyl-tRNA aminoacylation
NUG20_04125	COG1183	phosphatidylcholine synthase activity
NUG20_04155	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NUG20_04180	COG4974	Belongs to the 'phage' integrase family
NUG20_04190	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NUG20_04195	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NUG20_04195	COG0047	phosphoribosylformylglycinamidine synthase activity
NUG20_04200	COG5295	Hep Hag repeat protein
NUG20_04205	COG1404	Belongs to the peptidase S8 family
NUG20_04210	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NUG20_04215	COG1459	type II secretion system
NUG20_04220	COG2165	general secretion pathway protein
NUG20_04225	COG4970	Tfp pilus assembly protein FimT
NUG20_04230	COG2165	general secretion pathway protein
NUG20_04235	COG4795	General secretion pathway protein
NUG20_04240	COG3156	type II secretion system protein K
NUG20_04245	COG3166	PFAM Fimbrial assembly family protein
NUG20_04260	COG1450	Type ii and iii secretion system protein
NUG20_04275	COG1064	alcohol dehydrogenase
NUG20_04295	COG2188	Transcriptional regulator
NUG20_04335	COG1215	transferase activity, transferring glycosyl groups
NUG20_04340	COG1215	transferase activity, transferring glycosyl groups
NUG20_04345	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
NUG20_04350	COG0457	Tetratricopeptide repeat
NUG20_04355	COG0242	peptide deformylase activity
NUG20_04360	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
NUG20_04370	COG1215	transferase activity, transferring glycosyl groups
NUG20_04390	COG1696	Membrane protein involved in D-alanine export
NUG20_04400	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NUG20_04420	COG0488	(ABC) transporter
NUG20_04425	COG0477	Major facilitator Superfamily
NUG20_04445	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NUG20_04455	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NUG20_04455	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NUG20_04470	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
NUG20_04475	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NUG20_04500	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
NUG20_04505	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
NUG20_04515	COG2205	protein histidine kinase activity
NUG20_04520	COG0745	RESPONSE REGULATOR receiver
NUG20_04530	COG0277	FAD linked oxidase domain protein
NUG20_04535	COG1988	membrane-bound metal-dependent
NUG20_04540	COG0792	nuclease activity
NUG20_04575	COG2001	Belongs to the MraZ family
NUG20_04580	COG0275	rRNA processing
NUG20_04585	COG3116	cell division
NUG20_04600	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
NUG20_04615	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NUG20_04625	COG1181	Belongs to the D-alanine--D-alanine ligase family
NUG20_04630	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
NUG20_04640	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NUG20_04645	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
NUG20_04655	COG0739	heme binding
NUG20_04670	COG0494	nUDIX hydrolase
NUG20_04680	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
NUG20_04685	COG0366	Alpha amylase catalytic
NUG20_04705	COG3345	alpha-galactosidase
NUG20_04715	COG2222	sugar isomerase
NUG20_04740	COG1349	DNA-binding transcription factor activity
NUG20_04765	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
NUG20_04770	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
NUG20_04805	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NUG20_04825	COG4106	trans-aconitate 2-methyltransferase activity
NUG20_04830	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NUG20_04845	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NUG20_04850	COG0667	Aldo Keto reductase
NUG20_04860	COG4771	TonB-dependent receptor
NUG20_04880	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
NUG20_04885	COG4181	ATPase activity
NUG20_04900	COG0642	Histidine kinase
NUG20_04910	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
NUG20_04915	COG0861	Integral membrane protein TerC family
NUG20_04920	COG1704	LemA family
NUG20_04950	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
NUG20_04955	COG2967	ApaG domain
NUG20_04960	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
NUG20_04970	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
NUG20_04975	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NUG20_04990	COG2096	Adenosyltransferase
NUG20_05000	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NUG20_05005	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NUG20_05045	COG0697	spore germination
NUG20_05055	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NUG20_05080	COG2197	response regulator
NUG20_05100	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NUG20_05105	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NUG20_05115	COG0583	DNA-binding transcription factor activity
NUG20_05120	COG3634	alkyl hydroperoxide reductase activity
NUG20_05130	COG2890	protein-(glutamine-N5) methyltransferase activity
NUG20_05155	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NUG20_05155	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NUG20_05220	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NUG20_05225	COG1404	Belongs to the peptidase S8 family
NUG20_05230	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NUG20_05250	COG1295	ribonuclease BN
NUG20_05255	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NUG20_05275	COG0521	Mo-molybdopterin cofactor biosynthetic process
NUG20_05290	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NUG20_05295	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
NUG20_05310	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NUG20_05320	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NUG20_05330	COG0193	aminoacyl-tRNA hydrolase activity
NUG20_05335	COG0012	GTP binding
NUG20_05355	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NUG20_05370	COG0250	Participates in transcription elongation, termination and antitermination
NUG20_05375	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NUG20_05390	COG0222	ribosome binding
NUG20_05400	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NUG20_05415	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NUG20_05420	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NUG20_05425	COG0051	transcription antitermination factor activity, RNA binding
NUG20_05435	COG0088	Forms part of the polypeptide exit tunnel
NUG20_05440	COG0089	rRNA binding
NUG20_05445	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NUG20_05470	COG0255	Belongs to the universal ribosomal protein uL29 family
NUG20_05475	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NUG20_05485	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NUG20_05490	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NUG20_05520	COG1841	ribosomal large subunit assembly
NUG20_05530	COG0201	protein transport
NUG20_05545	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NUG20_05550	COG0202	RNA polymerase activity
NUG20_05555	COG0203	ribosomal protein L17
NUG20_05560	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
NUG20_05570	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
NUG20_05580	COG0154	amidase activity
NUG20_05590	COG1217	gtp-binding protein TYPA
NUG20_05595	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NUG20_05605	COG0039	L-malate dehydrogenase activity
NUG20_05615	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NUG20_05625	COG0625	glutathione transferase activity
NUG20_05635	COG0446	pyridine nucleotide-disulphide oxidoreductase
NUG20_05635	COG1902	pentaerythritol trinitrate reductase activity
NUG20_05645	COG0667	Aldo Keto reductase
NUG20_05655	COG2814	Major facilitator Superfamily
NUG20_05660	COG0583	DNA-binding transcription factor activity
NUG20_05665	COG2885	chlorophyll binding
NUG20_05675	COG1187	pseudouridine synthase activity
NUG20_05685	COG0156	8-amino-7-oxononanoate synthase activity
NUG20_05690	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
NUG20_05705	COG4208	sulfate ABC transporter
NUG20_05710	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
NUG20_05730	COG0588	phosphoglycerate mutase activity
NUG20_05740	COG0285	dihydrofolate synthase activity
NUG20_05760	COG2833	Protein of unknown function (DUF455)
NUG20_05765	COG3291	Pkd domain containing protein
NUG20_05775	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NUG20_05785	COG0438	transferase activity, transferring glycosyl groups
NUG20_05790	COG0248	Ppx GppA phosphatase
NUG20_05795	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
NUG20_05810	COG4783	chaperone-mediated protein folding
NUG20_05825	COG0473	3-isopropylmalate dehydrogenase activity
NUG20_05870	COG0544	peptidyl-prolyl cis-trans isomerase activity
NUG20_05880	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NUG20_05915	COG3942	CHAP domain
NUG20_05915	COG1388	LysM domain
NUG20_05920	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NUG20_05930	COG0328	RNA-DNA hybrid ribonuclease activity
NUG20_05940	COG0631	protein serine/threonine phosphatase activity
NUG20_05960	COG0859	PFAM glycosyl transferase family 9
NUG20_05970	COG1234	tRNA 3'-trailer cleavage
NUG20_05975	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NUG20_05985	COG0315	cyclic pyranopterin monophosphate synthase activity
NUG20_05990	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
NUG20_05995	COG0314	molybdopterin synthase activity
NUG20_06015	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NUG20_06030	COG0537	adenosine 5'-monophosphoramidase activity
NUG20_06050	COG0714	Associated with various cellular activities
NUG20_06075	COG1399	metal-binding, possibly nucleic acid-binding protein
NUG20_06085	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NUG20_06095	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
NUG20_06100	COG1028	Short-chain dehydrogenase reductase Sdr
NUG20_06115	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NUG20_06120	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NUG20_06125	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NUG20_06165	COG0640	Transcriptional regulator
NUG20_06190	COG0587	DNA-directed DNA polymerase activity
NUG20_06205	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NUG20_06215	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
NUG20_06220	COG0372	Belongs to the citrate synthase family
NUG20_06270	COG4771	TonB-dependent receptor
NUG20_06280	COG2373	Large extracellular alpha-helical protein
NUG20_06285	COG2223	nitrite transmembrane transporter activity
NUG20_06295	COG1349	DNA-binding transcription factor activity
NUG20_06300	COG4953	penicillin-binding protein 1C
NUG20_06310	COG0678	peroxiredoxin activity
NUG20_06310	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
NUG20_06330	COG0604	alcohol dehydrogenase
NUG20_06335	COG0330	HflC and HflK could
NUG20_06340	COG0330	HflC and HflK could
NUG20_06350	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NUG20_06430	COG3275	phosphorelay sensor kinase activity
NUG20_06440	COG3387	PFAM Glycoside hydrolase 15-related
NUG20_06445	COG1028	Short-chain dehydrogenase reductase Sdr
NUG20_06450	COG4221	oxidoreductase activity
NUG20_06470	COG0492	ferredoxin-NADP+ reductase activity
NUG20_06485	COG1028	Short-chain dehydrogenase reductase Sdr
NUG20_06505	COG1064	alcohol dehydrogenase
NUG20_06550	COG1028	Short-chain dehydrogenase reductase Sdr
NUG20_06555	COG2271	Major facilitator Superfamily
NUG20_06575	COG2186	Transcriptional regulator
NUG20_06580	COG3459	Glycosyltransferase 36 associated
NUG20_06590	COG1063	alcohol dehydrogenase
NUG20_06595	COG0753	catalase activity
NUG20_06600	COG4251	negative regulation of phosphorylation
NUG20_06600	COG3706	GGDEF domain
NUG20_06600	COG5001	Diguanylate cyclase
NUG20_06600	COG2203	Gaf domain
NUG20_06620	COG0789	Transcriptional regulator
NUG20_06625	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NUG20_06625	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NUG20_06630	COG2814	Major facilitator Superfamily
NUG20_06655	COG2194	sulfuric ester hydrolase activity
NUG20_06665	COG0745	RESPONSE REGULATOR receiver
NUG20_06670	COG2205	protein histidine kinase activity
NUG20_06680	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
NUG20_06685	COG2894	cell division
NUG20_06690	COG0850	regulation of cytokinetic process
NUG20_06700	COG4585	Histidine kinase
NUG20_06725	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
NUG20_06760	COG1073	alpha beta
NUG20_06780	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NUG20_06800	COG0840	transmembrane signaling receptor activity
NUG20_06820	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NUG20_06830	COG1946	Acyl-CoA thioesterase
NUG20_06835	COG1250	3-hydroxyacyl-CoA dehydrogenase
NUG20_06835	COG1024	Enoyl-CoA hydratase
NUG20_06840	COG0824	Thioesterase
NUG20_06845	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NUG20_06850	COG0261	This protein binds to 23S rRNA in the presence of protein L20
NUG20_06855	COG0211	Belongs to the bacterial ribosomal protein bL27 family
NUG20_06860	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NUG20_06875	COG0196	riboflavin kinase activity
NUG20_06890	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NUG20_06920	COG0251	oxidation-reduction process
NUG20_06945	COG4771	TonB-dependent receptor
NUG20_06960	COG2964	Protein conserved in bacteria
NUG20_06970	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NUG20_06975	COG1845	cytochrome c oxidase, subunit III
NUG20_06980	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
NUG20_07015	COG3152	Membrane
NUG20_07020	COG0129	dihydroxy-acid dehydratase activity
NUG20_07025	COG1028	Short-chain dehydrogenase reductase Sdr
NUG20_07040	COG1012	belongs to the aldehyde dehydrogenase family
NUG20_07045	COG1879	ABC-type sugar transport system periplasmic component
NUG20_07050	COG1129	ABC transporter
NUG20_07055	COG1172	Belongs to the binding-protein-dependent transport system permease family
NUG20_07060	COG1172	Belongs to the binding-protein-dependent transport system permease family
NUG20_07070	COG1082	Xylose isomerase domain protein TIM barrel
NUG20_07075	COG0625	glutathione transferase activity
NUG20_07095	COG0475	glutathione-regulated potassium exporter activity
NUG20_07115	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NUG20_07140	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NUG20_07165	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NUG20_07175	COG0335	large ribosomal subunit rRNA binding
NUG20_07180	COG0534	Mate efflux family protein
NUG20_07190	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
NUG20_07195	COG0542	response to heat
NUG20_07235	COG3540	Alkaline phosphatase
NUG20_07245	COG2855	membrane
NUG20_07250	COG1028	Short-chain dehydrogenase reductase Sdr
NUG20_07255	COG2124	cytochrome p450
NUG20_07280	COG1024	Enoyl-CoA hydratase
NUG20_07280	COG1250	3-hydroxyacyl-CoA dehydrogenase
NUG20_07295	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NUG20_07300	COG0481	GTPase activity
NUG20_07305	COG0681	Belongs to the peptidase S26 family
NUG20_07320	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NUG20_07325	COG1381	Involved in DNA repair and RecF pathway recombination
NUG20_07330	COG0745	RESPONSE REGULATOR receiver
NUG20_07340	COG2954	triphosphatase activity
NUG20_07350	COG1472	Belongs to the glycosyl hydrolase 3 family
NUG20_07355	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
NUG20_07360	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
NUG20_07365	COG1278	Cold shock
NUG20_07370	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NUG20_07380	COG1201	RNA secondary structure unwinding
NUG20_07385	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
NUG20_07385	COG1793	dna ligase
NUG20_07390	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
NUG20_07390	COG1793	dna ligase
NUG20_07395	COG1960	acyl-CoA dehydrogenase activity
NUG20_07425	COG0183	Belongs to the thiolase family
NUG20_07455	COG1703	isobutyryl-CoA mutase activity
NUG20_07455	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
NUG20_07455	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
NUG20_07530	COG1451	nucleotide metabolic process
NUG20_07540	COG1028	Short-chain dehydrogenase reductase Sdr
NUG20_07545	COG0583	DNA-binding transcription factor activity
NUG20_07550	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
NUG20_07585	COG1077	Cell shape determining protein MreB Mrl
NUG20_07590	COG1047	Peptidyl-prolyl cis-trans
NUG20_07600	COG2824	Alkylphosphonate utilization operon protein PhnA
NUG20_07615	COG0583	DNA-binding transcription factor activity
NUG20_07625	COG1902	pentaerythritol trinitrate reductase activity
NUG20_07630	COG2814	Major facilitator Superfamily
NUG20_07665	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NUG20_07665	COG0392	lysyltransferase activity
NUG20_07675	COG0251	oxidation-reduction process
NUG20_07695	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
NUG20_07720	COG1595	DNA-templated transcription, initiation
NUG20_07735	COG2878	Part of a membrane complex involved in electron transport
NUG20_07760	COG1131	(ABC) transporter
NUG20_07765	COG0346	lactoylglutathione lyase activity
NUG20_07780	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
NUG20_07795	COG4251	negative regulation of phosphorylation
NUG20_07795	COG2203	Gaf domain
NUG20_07795	COG3706	GGDEF domain
NUG20_07795	COG5001	Diguanylate cyclase
NUG20_07805	COG3118	belongs to the thioredoxin family
NUG20_07815	COG0495	leucyl-tRNA aminoacylation
NUG20_07830	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NUG20_07850	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NUG20_07865	COG2968	Membrane
NUG20_07885	COG0312	modulator of DNA gyrase
NUG20_07895	COG0312	modulator of DNA gyrase
NUG20_07915	COG4104	PAAR repeat-containing protein
NUG20_07925	COG0142	geranyltranstransferase activity
NUG20_07930	COG1722	exodeoxyribonuclease VII activity
NUG20_07935	COG0037	tRNA processing
NUG20_07945	COG1785	Belongs to the alkaline phosphatase family
NUG20_07950	COG1301	dicarboxylic acid transport
NUG20_07955	COG4106	trans-aconitate 2-methyltransferase activity
NUG20_07960	COG1607	acyl-coa hydrolase
NUG20_07965	COG0791	NLP P60 protein
NUG20_07970	COG0791	NLP P60 protein
NUG20_07980	COG2311	Membrane
NUG20_08010	COG3590	peptidase
NUG20_08020	COG0457	Tetratricopeptide repeat
NUG20_08025	COG4771	TonB-dependent receptor
NUG20_08030	COG0489	protein tyrosine kinase activity
NUG20_08035	COG0717	Belongs to the dCTP deaminase family
NUG20_08040	COG1714	RDD family
NUG20_08060	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NUG20_08075	COG0494	nUDIX hydrolase
NUG20_08085	COG0433	COG0433 Predicted ATPase
NUG20_08105	COG0688	phosphatidylethanolamine metabolic process
NUG20_08115	COG2890	protein-(glutamine-N5) methyltransferase activity
NUG20_08130	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NUG20_08140	COG0101	tRNA pseudouridine synthase activity
NUG20_08155	COG0133	tryptophan synthase activity
NUG20_08165	COG0159	tryptophan synthase activity
NUG20_08170	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NUG20_08185	COG1028	Short-chain dehydrogenase reductase Sdr
NUG20_08205	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NUG20_08215	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NUG20_08220	COG0649	NAD binding
NUG20_08225	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
NUG20_08230	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
NUG20_08235	COG1034	ATP synthesis coupled electron transport
NUG20_08270	COG1007	ATP synthesis coupled electron transport
NUG20_08285	COG0195	Participates in both transcription termination and antitermination
NUG20_08310	COG1185	polyribonucleotide nucleotidyltransferase activity
NUG20_08315	COG5001	Diguanylate cyclase
NUG20_08315	COG3300	MHYT domain
NUG20_08330	COG1201	RNA secondary structure unwinding
NUG20_08335	COG0840	transmembrane signaling receptor activity
NUG20_08340	COG0835	chemotaxis
NUG20_08375	COG2304	oxidoreductase activity
NUG20_08390	COG1194	a g-specific adenine glycosylase
NUG20_08395	COG0552	protein localization to endoplasmic reticulum
NUG20_08405	COG3938	Belongs to the proline racemase family
NUG20_08410	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NUG20_08425	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NUG20_08435	COG0006	proline dipeptidase activity
NUG20_08450	COG0531	amino acid
NUG20_08455	COG1506	peptidase
NUG20_08455	COG0823	Involved in the tonB-independent uptake of proteins
NUG20_08480	COG3507	Belongs to the glycosyl hydrolase 43 family
NUG20_08485	COG1506	peptidase
NUG20_08485	COG0823	Involved in the tonB-independent uptake of proteins
NUG20_08490	COG4206	TonB-dependent receptor
NUG20_08500	COG3345	alpha-galactosidase
NUG20_08520	COG3209	COG3209 Rhs family protein
NUG20_08530	COG0326	Molecular chaperone. Has ATPase activity
NUG20_08535	COG0742	ribosomal rna small subunit methyltransferase
NUG20_08550	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
NUG20_08560	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NUG20_08565	COG3291	Pkd domain containing protein
NUG20_08570	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NUG20_08590	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NUG20_08615	COG1862	Preprotein translocase
NUG20_08620	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NUG20_08655	COG1509	lysine 2,3-aminomutase activity
NUG20_08665	COG3548	integral membrane protein
NUG20_08670	COG0402	S-adenosylhomocysteine deaminase activity
NUG20_08700	COG4302	ethanolamine ammonia-lyase activity
NUG20_08705	COG4303	Ethanolamine ammonia lyase large subunit
NUG20_08730	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
NUG20_08765	COG2166	iron-sulfur cluster assembly
NUG20_08780	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NUG20_08785	COG0137	argininosuccinate synthase activity
NUG20_08795	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NUG20_08800	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
NUG20_08810	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NUG20_08815	COG0165	Argininosuccinate lyase
NUG20_08830	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NUG20_08855	COG1294	oxidase, subunit
NUG20_08865	COG4988	ABC transporter
NUG20_08870	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
NUG20_08875	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NUG20_08895	COG1138	Cytochrome C-type biogenesis protein
NUG20_08900	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
NUG20_08920	COG4133	protoheme IX ABC transporter activity
NUG20_08925	COG0436	Aminotransferase
NUG20_08950	COG1187	pseudouridine synthase activity
NUG20_08955	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NUG20_08960	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NUG20_08965	COG2350	Protein conserved in bacteria
NUG20_09000	COG0395	ABC-type sugar transport system, permease component
NUG20_09010	COG0800	Aldolase
NUG20_09015	COG0129	dihydroxy-acid dehydratase activity
NUG20_09030	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NUG20_09055	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
NUG20_09080	COG4591	ABC-type transport system involved in lipoprotein release permease component
NUG20_09105	COG0811	peptide transport
NUG20_09110	COG0848	biopolymer transport protein
NUG20_09115	COG1132	(ABC) transporter
NUG20_09120	COG1663	tetraacyldisaccharide 4'-kinase activity
NUG20_09130	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NUG20_09145	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NUG20_09175	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NUG20_09190	COG0348	domain, Protein
NUG20_09205	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NUG20_09215	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
NUG20_09220	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NUG20_09230	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NUG20_09280	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NUG20_09280	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NUG20_09285	COG1105	Belongs to the carbohydrate kinase PfkB family
NUG20_09290	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
NUG20_09290	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NUG20_09295	COG1609	Transcriptional regulator
NUG20_09310	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
NUG20_09315	COG0069	glutamate synthase activity
NUG20_09350	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NUG20_09365	COG1253	flavin adenine dinucleotide binding
NUG20_09375	COG0306	phosphate transporter
NUG20_09385	COG2134	cdp-diacylglycerol pyrophosphatase
NUG20_09420	COG0504	CTP synthase activity
NUG20_09425	COG2877	3-deoxy-8-phosphooctulonate synthase activity
NUG20_09440	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
NUG20_09445	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
NUG20_09455	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
NUG20_09470	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
NUG20_09475	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
NUG20_09480	COG1238	metal cluster binding
NUG20_09495	COG1534	Rna-binding protein
NUG20_09500	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
NUG20_09505	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NUG20_09510	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NUG20_09525	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NUG20_09530	COG1546	Belongs to the CinA family
NUG20_09535	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
NUG20_09540	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NUG20_09545	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NUG20_09550	COG2137	regulation of response to DNA damage stimulus
NUG20_09555	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NUG20_09560	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
NUG20_09570	COG2207	Transcriptional regulator
NUG20_09595	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NUG20_09615	COG1741	Belongs to the pirin family
NUG20_09620	COG0583	DNA-binding transcription factor activity
NUG20_09645	COG0351	phosphomethylpyrimidine kinase
NUG20_09645	COG0352	thiamine-phosphate diphosphorylase activity
NUG20_09660	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
NUG20_09665	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NUG20_09675	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NUG20_09685	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
NUG20_09690	COG3734	2-keto-3-deoxy-galactonokinase
NUG20_09700	COG4948	Mandelate Racemase Muconate Lactonizing
NUG20_09705	COG0800	Aldolase
NUG20_09740	COG1501	Belongs to the glycosyl hydrolase 31 family
NUG20_09750	COG1070	Carbohydrate kinase
NUG20_09755	COG2115	Belongs to the xylose isomerase family
NUG20_09760	COG0477	Major facilitator Superfamily
NUG20_09770	COG0617	tRNA 3'-terminal CCA addition
NUG20_09780	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
NUG20_09795	COG0166	Belongs to the GPI family
NUG20_09810	COG0784	Response regulator, receiver
NUG20_09810	COG2205	protein histidine kinase activity
NUG20_09840	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
NUG20_09855	COG0671	phosphoesterase, PA-phosphatase related
NUG20_09860	COG1794	racemase activity, acting on amino acids and derivatives
NUG20_09865	COG0210	DNA helicase
NUG20_09880	COG0812	UDP-N-acetylmuramate dehydrogenase activity
NUG20_09905	COG1012	belongs to the aldehyde dehydrogenase family
NUG20_09920	COG0460	homoserine dehydrogenase
NUG20_09920	COG0527	aspartate kinase activity
NUG20_09925	COG0083	homoserine kinase activity
NUG20_09935	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NUG20_09945	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NUG20_09950	COG0124	histidyl-tRNA synthetase
NUG20_09960	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
NUG20_09965	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NUG20_09980	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NUG20_09985	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NUG20_09995	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NUG20_09995	COG0140	phosphoribosyl-ATP diphosphatase activity
NUG20_10015	COG3537	Alpha-1,2-mannosidase
NUG20_10020	COG1609	Transcriptional regulator
NUG20_10030	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
NUG20_10035	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
NUG20_10040	COG0235	Class ii aldolase
NUG20_10045	COG0531	amino acid
NUG20_10050	COG0531	amino acid
NUG20_10065	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NUG20_10070	COG0277	FAD linked oxidase domain protein
NUG20_10090	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NUG20_10110	COG1024	Enoyl-CoA hydratase
NUG20_10135	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NUG20_10140	COG2258	MOSC domain
NUG20_10150	COG0505	Belongs to the CarA family
NUG20_10160	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
NUG20_10165	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NUG20_10175	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
NUG20_10180	COG4676	Protein conserved in bacteria
NUG20_10205	COG2205	protein histidine kinase activity
NUG20_10205	COG2198	Histidine kinase
NUG20_10205	COG0784	Response regulator, receiver
NUG20_10215	COG0318	PFAM AMP-dependent synthetase and ligase
NUG20_10270	COG0840	transmembrane signaling receptor activity
NUG20_10280	COG0840	transmembrane signaling receptor activity
NUG20_10285	COG0840	transmembrane signaling receptor activity
NUG20_10295	COG0835	chemotaxis
NUG20_10305	COG0840	transmembrane signaling receptor activity
NUG20_10315	COG0840	transmembrane signaling receptor activity
NUG20_10320	COG0840	transmembrane signaling receptor activity
NUG20_10325	COG0840	transmembrane signaling receptor activity
NUG20_10335	COG0840	transmembrane signaling receptor activity
NUG20_10345	COG0840	transmembrane signaling receptor activity
NUG20_10350	COG0840	transmembrane signaling receptor activity
NUG20_10360	COG0840	transmembrane signaling receptor activity
NUG20_10370	COG0745	RESPONSE REGULATOR receiver
NUG20_10385	COG1192	Involved in chromosome partitioning
NUG20_10395	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
NUG20_10400	COG0643	Histidine kinase
NUG20_10400	COG0784	Response regulator, receiver
NUG20_10400	COG2198	Histidine kinase
NUG20_10405	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
NUG20_10455	COG1684	flagellar biosynthetic protein fliR
NUG20_10470	COG3190	flagellar
NUG20_10520	COG1677	Flagellar hook-basal body complex protein FliE
NUG20_10525	COG0438	transferase activity, transferring glycosyl groups
NUG20_10525	COG1216	Glycosyl transferase, family 2
NUG20_10540	COG1215	transferase activity, transferring glycosyl groups
NUG20_10550	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NUG20_10555	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
NUG20_10565	COG2201	protein-glutamate methylesterase activity
NUG20_10570	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
NUG20_10575	COG2197	response regulator
NUG20_10595	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
NUG20_10610	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NUG20_10615	COG1256	bacterial-type flagellum assembly
NUG20_10630	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
NUG20_10645	COG1749	Flagellar hook protein flgE
NUG20_10650	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
NUG20_10655	COG1558	bacterial-type flagellum-dependent cell motility
NUG20_10665	COG0784	Response regulator, receiver
NUG20_10665	COG0835	chemotaxis
NUG20_10710	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NUG20_10715	COG1116	anion transmembrane transporter activity
NUG20_10735	COG2915	High frequency lysogenization protein hflD homolog
NUG20_10740	COG0482	sulfurtransferase activity
NUG20_10760	COG0542	response to heat
NUG20_10785	COG0492	ferredoxin-NADP+ reductase activity
NUG20_10790	COG1674	ftsk spoiiie
NUG20_10805	COG1230	cation diffusion facilitator family transporter
NUG20_10810	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
NUG20_10815	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NUG20_10845	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NUG20_10880	COG1595	DNA-templated transcription, initiation
NUG20_10900	COG3038	cytochrome b561
NUG20_10930	COG2244	polysaccharide biosynthetic process
NUG20_10970	COG0297	glycogen (starch) synthase activity
NUG20_10975	COG0438	transferase activity, transferring glycosyl groups
NUG20_10995	COG1132	(ABC) transporter
NUG20_11040	COG3210	domain, Protein
NUG20_11050	COG3552	Protein containing von Willebrand factor type A (VWA) domain
NUG20_11060	COG0714	Associated with various cellular activities
NUG20_11075	COG4585	Histidine kinase
NUG20_11085	COG1028	Short-chain dehydrogenase reductase Sdr
NUG20_11090	COG2197	response regulator
NUG20_11115	COG2207	Transcriptional regulator
NUG20_11155	COG1222	aaa ATPase
NUG20_11240	COG2205	protein histidine kinase activity
NUG20_11245	COG0745	RESPONSE REGULATOR receiver
NUG20_11255	COG0583	DNA-binding transcription factor activity
NUG20_11295	COG3525	Glycosyl hydrolase, family 20, catalytic domain
NUG20_11305	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
NUG20_11340	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NUG20_11345	COG0318	PFAM AMP-dependent synthetase and ligase
NUG20_11350	COG2366	antibiotic biosynthetic process
NUG20_11360	COG0577	efflux transmembrane transporter activity
NUG20_11370	COG1136	(ABC) transporter
NUG20_11375	COG5002	protein histidine kinase activity
NUG20_11375	COG5000	phosphorelay sensor kinase activity
NUG20_11390	COG3713	MltA-interacting MipA family protein
NUG20_11440	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NUG20_11440	COG2205	protein histidine kinase activity
NUG20_11440	COG0784	Response regulator, receiver
NUG20_11440	COG2198	Histidine kinase
NUG20_11445	COG2183	response to ionizing radiation
NUG20_11450	COG0784	Response regulator, receiver
NUG20_11450	COG4191	Histidine kinase
NUG20_11480	COG3243	poly(R)-hydroxyalkanoic acid synthase
NUG20_11490	COG1183	phosphatidylcholine synthase activity
NUG20_11495	COG1028	Short-chain dehydrogenase reductase Sdr
NUG20_11520	COG0668	transmembrane transport
NUG20_11540	COG1914	H( )-stimulated, divalent metal cation uptake system
NUG20_11550	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
NUG20_11560	COG4191	Histidine kinase
NUG20_11560	COG0784	Response regulator, receiver
NUG20_11575	COG1505	serine-type exopeptidase activity
NUG20_11585	COG0642	Histidine kinase
NUG20_11590	COG0745	RESPONSE REGULATOR receiver
NUG20_11610	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NUG20_11640	COG4773	Receptor
NUG20_11645	COG0475	glutathione-regulated potassium exporter activity
NUG20_11645	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NUG20_11650	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NUG20_11660	COG0746	molybdenum cofactor guanylyltransferase activity
NUG20_11670	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NUG20_11690	COG0820	rRNA (adenine-C2-)-methyltransferase activity
NUG20_11705	COG1250	3-hydroxyacyl-CoA dehydrogenase
NUG20_11705	COG1024	Enoyl-CoA hydratase
NUG20_11710	COG0183	Belongs to the thiolase family
NUG20_11715	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NUG20_11725	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NUG20_11730	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
NUG20_11740	COG0776	regulation of translation
NUG20_11745	COG0539	negative regulation of cytoplasmic translation
NUG20_11750	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
NUG20_11765	COG2957	Belongs to the agmatine deiminase family
NUG20_11770	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NUG20_11795	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NUG20_11815	COG0316	Belongs to the HesB IscA family
NUG20_11815	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
NUG20_11830	COG0428	transporter
NUG20_11845	COG1530	ribonuclease E activity
NUG20_11860	COG0583	DNA-binding transcription factor activity
NUG20_11885	COG0077	Prephenate dehydratase
NUG20_11885	COG1605	Chorismate mutase
NUG20_11890	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NUG20_11895	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
NUG20_11935	COG4221	oxidoreductase activity
NUG20_11965	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
NUG20_12015	COG4993	Dehydrogenase
NUG20_12035	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
NUG20_12040	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NUG20_12045	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NUG20_12075	COG2977	Belongs to the P-Pant transferase superfamily
NUG20_12080	COG0316	Belongs to the HesB IscA family
NUG20_12110	COG0288	reversible hydration of carbon dioxide
NUG20_12115	COG0662	Cupin 2, conserved barrel domain protein
NUG20_12120	COG1289	transmembrane transporter activity
NUG20_12125	COG3844	kynureninase activity
NUG20_12135	COG2925	Exonuclease
NUG20_12165	COG2902	Dehydrogenase
NUG20_12175	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NUG20_12180	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NUG20_12185	COG1960	acyl-CoA dehydrogenase activity
NUG20_12190	COG2226	methyltransferase
NUG20_12195	COG1410	methionine synthase
NUG20_12195	COG0646	methionine synthase
NUG20_12200	COG1410	methionine synthase
NUG20_12200	COG0646	methionine synthase
NUG20_12225	COG2900	Belongs to the SlyX family
NUG20_12240	COG0386	Belongs to the glutathione peroxidase family
NUG20_12250	COG1725	Transcriptional regulator
NUG20_12255	COG1131	(ABC) transporter
NUG20_12305	COG2850	peptidyl-arginine hydroxylation
NUG20_12360	COG1132	(ABC) transporter
NUG20_12370	COG0287	Prephenate dehydrogenase
NUG20_12370	COG1605	Chorismate mutase
NUG20_12375	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
NUG20_12380	COG0484	heat shock protein binding
NUG20_12385	COG0443	Heat shock 70 kDa protein
NUG20_12390	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NUG20_12395	COG1420	regulation of RNA biosynthetic process
NUG20_12400	COG0497	DNA recombination
NUG20_12405	COG0735	belongs to the Fur family
NUG20_12410	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NUG20_12430	COG1404	Belongs to the peptidase S8 family
NUG20_12460	COG0583	DNA-binding transcription factor activity
NUG20_12465	COG3706	GGDEF domain
NUG20_12485	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NUG20_12500	COG0583	DNA-binding transcription factor activity
NUG20_12510	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NUG20_12515	COG0415	Belongs to the DNA photolyase family
NUG20_12520	COG2204	response regulator
NUG20_12525	COG2204	response regulator
NUG20_12530	COG4191	Histidine kinase
NUG20_12540	COG0305	Participates in initiation and elongation during chromosome replication
NUG20_12560	COG1960	acyl-CoA dehydrogenase activity
NUG20_12575	COG0084	hydrolase, TatD family'
NUG20_12595	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
NUG20_12625	COG0625	glutathione transferase activity
NUG20_12640	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NUG20_12665	COG0386	Belongs to the glutathione peroxidase family
NUG20_12670	COG1228	amidohydrolase
NUG20_12675	COG0339	signal peptide processing
NUG20_12680	COG1846	Transcriptional regulator
NUG20_12685	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
NUG20_12735	COG2197	response regulator
NUG20_12750	COG2207	Transcriptional regulator
NUG20_12755	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NUG20_12770	COG0488	(ABC) transporter
NUG20_12780	COG0513	Belongs to the DEAD box helicase family
NUG20_12800	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NUG20_12820	COG0625	glutathione transferase activity
NUG20_12830	COG0564	pseudouridine synthase activity
NUG20_12835	COG4681	YaeQ
NUG20_12840	COG2081	HI0933 family
NUG20_12860	COG1028	Short-chain dehydrogenase reductase Sdr
NUG20_12885	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NUG20_12890	COG0860	N-Acetylmuramoyl-L-alanine amidase
NUG20_12895	COG0802	atpase or kinase
NUG20_12900	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NUG20_12900	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
NUG20_12905	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NUG20_12945	COG1846	Transcriptional regulator
NUG20_12960	COG1566	PFAM secretion protein HlyD family protein
NUG20_12965	COG1960	acyl-CoA dehydrogenase activity
NUG20_12975	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NUG20_13000	COG0438	transferase activity, transferring glycosyl groups
NUG20_13010	COG0438	transferase activity, transferring glycosyl groups
NUG20_13015	COG0438	transferase activity, transferring glycosyl groups
NUG20_13060	COG0072	phenylalanine-tRNA ligase activity
NUG20_13060	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NUG20_13065	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NUG20_13070	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NUG20_13080	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NUG20_13120	COG0366	Alpha amylase catalytic
NUG20_13140	COG3702	type iv secretory pathway
NUG20_13160	COG2948	multi-organism process
NUG20_13200	COG0556	nucleotide-excision repair
NUG20_13245	COG3275	phosphorelay sensor kinase activity
NUG20_13250	COG1611	Belongs to the LOG family
NUG20_13265	COG2095	MarC family integral membrane protein
NUG20_13270	COG1028	Short-chain dehydrogenase reductase Sdr
NUG20_13275	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
NUG20_13315	COG2969	positive regulation of protein catabolic process
NUG20_13320	COG0625	glutathione transferase activity
NUG20_13325	COG2857	Cytochrome c1
NUG20_13335	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
NUG20_13340	COG0723	plastoquinol--plastocyanin reductase activity
NUG20_13345	COG0741	lytic transglycosylase activity
NUG20_13370	COG0277	FAD linked oxidase domain protein
NUG20_13375	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
NUG20_13380	COG1702	phosphate starvation-inducible protein PhoH
NUG20_13410	COG4535	Mg2 and Co2 transporter CorC
NUG20_13420	COG0598	Magnesium transport protein CorA
NUG20_13425	COG1012	belongs to the aldehyde dehydrogenase family
NUG20_13430	COG1177	transmembrane transport
NUG20_13435	COG1176	ABC-type spermidine putrescine transport system, permease component I
NUG20_13440	COG3842	ATPase activity
NUG20_13460	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
NUG20_13465	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
NUG20_13480	COG0174	glutamine synthetase
NUG20_13490	COG0174	glutamine synthetase
NUG20_13495	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NUG20_13500	COG0477	Major facilitator Superfamily
NUG20_13510	COG0243	molybdopterin cofactor binding
NUG20_13520	COG2223	nitrite transmembrane transporter activity
NUG20_13535	COG1012	belongs to the aldehyde dehydrogenase family
NUG20_13540	COG1396	sequence-specific DNA binding
NUG20_13540	COG1917	Cupin 2, conserved barrel domain protein
NUG20_13545	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NUG20_13550	COG0686	Belongs to the AlaDH PNT family
NUG20_13570	COG2205	protein histidine kinase activity
NUG20_13585	COG2733	membrane
NUG20_13590	COG0784	Response regulator, receiver
NUG20_13590	COG2205	protein histidine kinase activity
NUG20_13590	COG5002	protein histidine kinase activity
NUG20_13605	COG0488	(ABC) transporter
NUG20_13650	COG1024	Enoyl-CoA hydratase
NUG20_13660	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NUG20_13665	COG0659	secondary active sulfate transmembrane transporter activity
NUG20_13685	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
NUG20_13695	COG0573	inorganic phosphate transmembrane transporter activity
NUG20_13700	COG0581	inorganic phosphate transmembrane transporter activity
NUG20_13710	COG0704	Plays a role in the regulation of phosphate uptake
NUG20_13720	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NUG20_13740	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NUG20_13750	COG0557	exoribonuclease II activity
NUG20_13785	COG2814	Major facilitator Superfamily
NUG20_13790	COG1566	PFAM secretion protein HlyD family protein
NUG20_13830	COG3706	GGDEF domain
NUG20_13835	COG0367	asparagine synthase
NUG20_13840	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NUG20_13845	COG1393	Belongs to the ArsC family
NUG20_13870	COG0024	Methionine aminopeptidase
NUG20_13905	COG0052	Belongs to the universal ribosomal protein uS2 family
NUG20_13910	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NUG20_13920	COG0528	UMP kinase activity
NUG20_13930	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NUG20_13935	COG0575	Belongs to the CDS family
NUG20_13940	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
NUG20_13945	COG0750	zinc metalloprotease
NUG20_13950	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NUG20_13955	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NUG20_13965	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NUG20_13990	COG0825	malonyl-CoA metabolic process
NUG20_14005	COG1981	membrane
NUG20_14090	COG1132	(ABC) transporter
NUG20_14125	COG4941	Belongs to the sigma-70 factor family
NUG20_14135	COG2764	glyoxalase bleomycin resistance protein dioxygenase
NUG20_14140	COG3795	YCII-related domain
NUG20_14145	COG3795	YCII-related domain
NUG20_14165	COG1187	pseudouridine synthase activity
NUG20_14225	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NUG20_14260	COG2080	2 iron, 2 sulfur cluster binding
NUG20_14265	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
NUG20_14270	COG1529	Aldehyde oxidase and xanthine dehydrogenase
NUG20_14280	COG0746	molybdenum cofactor guanylyltransferase activity
NUG20_14290	COG4191	Histidine kinase
NUG20_14290	COG0784	Response regulator, receiver
NUG20_14300	COG3214	Protein conserved in bacteria
NUG20_14325	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NUG20_14375	COG0735	belongs to the Fur family
NUG20_14405	COG4452	Inner membrane protein CreD
NUG20_14410	COG2205	protein histidine kinase activity
NUG20_14415	COG0745	RESPONSE REGULATOR receiver
NUG20_14420	COG3111	PFAM Bacterial OB fold (BOF) protein
NUG20_14425	COG0642	Histidine kinase
NUG20_14435	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
NUG20_14440	COG3878	Protein conserved in bacteria
NUG20_14455	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NUG20_14470	COG0643	Histidine kinase
NUG20_14470	COG2198	Histidine kinase
NUG20_14480	COG0840	transmembrane signaling receptor activity
NUG20_14485	COG0835	chemotaxis
NUG20_14490	COG3706	GGDEF domain
NUG20_14490	COG4251	negative regulation of phosphorylation
NUG20_14490	COG5001	Diguanylate cyclase
NUG20_14490	COG2203	Gaf domain
NUG20_14505	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NUG20_14515	COG2211	Major facilitator Superfamily
NUG20_14530	COG0588	phosphoglycerate mutase activity
NUG20_14540	COG1741	Belongs to the pirin family
NUG20_14545	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
NUG20_14555	COG1741	Belongs to the pirin family
NUG20_14560	COG1966	Carbon starvation protein
NUG20_14565	COG2879	small protein
NUG20_14570	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NUG20_14590	COG1506	peptidase
NUG20_14590	COG0823	Involved in the tonB-independent uptake of proteins
NUG20_14595	COG1297	OPT oligopeptide transporter protein
NUG20_14605	COG3104	oligopeptide transport
NUG20_14635	COG1609	Transcriptional regulator
NUG20_14645	COG2211	Major facilitator Superfamily
NUG20_14650	COG0673	inositol 2-dehydrogenase activity
NUG20_14660	COG2010	Cytochrome c
NUG20_14685	COG0629	single-stranded DNA binding
NUG20_14690	COG0142	geranyltranstransferase activity
NUG20_14700	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NUG20_14715	COG0527	aspartate kinase activity
NUG20_14720	COG0384	phenazine biosynthesis protein PhzF
NUG20_14730	COG1764	response to oxidative stress
NUG20_14745	COG0739	heme binding
NUG20_14760	COG0693	protein deglycase activity
NUG20_14775	COG0719	Fe-S assembly protein
NUG20_14780	COG0396	ATPase activity
NUG20_14785	COG0719	Fe-S assembly protein
NUG20_14790	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NUG20_14805	COG4774	siderophore transport
NUG20_14830	COG1477	protein flavinylation
NUG20_14835	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NUG20_14850	COG1555	photosystem II stabilization
NUG20_14865	COG3178	'Phosphotransferase
NUG20_14870	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
NUG20_14880	COG0628	permease
NUG20_14905	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NUG20_14940	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
NUG20_14950	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
NUG20_14955	COG1137	ATPase activity
NUG20_14970	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NUG20_14980	COG1660	Displays ATPase and GTPase activities
NUG20_14990	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NUG20_14995	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NUG20_15000	COG2239	Acts as a magnesium transporter
NUG20_15020	COG1113	amino acid transport
NUG20_15065	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NUG20_15080	COG0519	Catalyzes the synthesis of GMP from XMP
NUG20_15120	COG3706	GGDEF domain
NUG20_15180	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NUG20_15195	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
NUG20_15200	COG0477	Major facilitator Superfamily
NUG20_15220	COG3038	cytochrome b561
NUG20_15245	COG1760	l-serine dehydratase
NUG20_15250	COG3706	GGDEF domain
NUG20_15270	COG0527	aspartate kinase activity
NUG20_15270	COG0460	homoserine dehydrogenase
NUG20_15275	COG0626	cystathionine gamma-synthase activity
NUG20_15280	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NUG20_15285	COG0739	heme binding
NUG20_15290	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NUG20_15295	COG1272	protein, Hemolysin III
NUG20_15300	COG2982	Protein involved in outer membrane biogenesis
NUG20_15305	COG0517	IMP dehydrogenase activity
NUG20_15310	COG0463	Glycosyl transferase, family 2
NUG20_15315	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NUG20_15320	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NUG20_15335	COG0457	Tetratricopeptide repeat
NUG20_15350	COG1309	transcriptional regulator
NUG20_15360	COG1960	acyl-CoA dehydrogenase activity
NUG20_15385	COG0697	spore germination
NUG20_15415	COG0330	HflC and HflK could
NUG20_15430	COG3956	TIGRFAM MazG family protein
NUG20_15440	COG0494	nUDIX hydrolase
NUG20_15450	COG1385	rRNA (uridine-N3-)-methyltransferase activity
NUG20_15460	COG0837	glucose binding
NUG20_15475	COG3858	chitin binding
NUG20_15475	COG1388	LysM domain
NUG20_15480	COG3525	Glycosyl hydrolase, family 20, catalytic domain
NUG20_15490	COG1472	Belongs to the glycosyl hydrolase 3 family
NUG20_15500	COG3537	Alpha-1,2-mannosidase
NUG20_15555	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NUG20_15590	COG4316	Uncharacterized protein conserved in bacteria (DUF2251)
NUG20_15615	COG1446	asparaginase
NUG20_15660	COG0643	Histidine kinase
NUG20_15660	COG0784	Response regulator, receiver
NUG20_15660	COG2198	Histidine kinase
NUG20_15665	COG0840	transmembrane signaling receptor activity
NUG20_15670	COG0835	chemotaxis
NUG20_15685	COG0189	ligase activity
NUG20_15700	COG1397	ADP-ribosylglycohydrolase
NUG20_15710	COG1199	ATP-dependent helicase activity
NUG20_15720	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NUG20_15725	COG1216	Glycosyl transferase, family 2
NUG20_15735	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NUG20_15775	COG1643	Atp-dependent helicase
NUG20_15780	COG0783	Belongs to the Dps family
NUG20_15790	COG0514	ATP-dependent DNA helicase (RecQ)
NUG20_15825	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NUG20_15830	COG0602	queuosine metabolic process
NUG20_15840	COG2885	chlorophyll binding
NUG20_15845	COG0823	Involved in the tonB-independent uptake of proteins
NUG20_15855	COG0848	biopolymer transport protein
NUG20_15865	COG0824	Thioesterase
NUG20_15880	COG0632	four-way junction helicase activity
NUG20_15890	COG0217	transcriptional regulatory protein
NUG20_15910	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NUG20_15955	COG0488	(ABC) transporter
NUG20_15985	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NUG20_15985	COG4651	solute:proton antiporter activity
NUG20_15995	COG2223	nitrite transmembrane transporter activity
NUG20_16005	COG1733	regulation of RNA biosynthetic process
NUG20_16010	COG1028	Short-chain dehydrogenase reductase Sdr
NUG20_16020	COG0542	response to heat
NUG20_16045	COG0454	-acetyltransferase
NUG20_16065	COG3387	PFAM Glycoside hydrolase 15-related
NUG20_16075	COG4993	Dehydrogenase
NUG20_16080	COG0840	transmembrane signaling receptor activity
NUG20_16100	COG0564	pseudouridine synthase activity
NUG20_16105	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NUG20_16110	COG1125	glycine betaine transport
NUG20_16125	COG1262	PFAM Formylglycine-generating sulfatase enzyme
NUG20_16135	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NUG20_16135	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
NUG20_16145	COG2755	lipolytic protein G-D-S-L family
NUG20_16145	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
NUG20_16175	COG1216	Glycosyl transferase, family 2
NUG20_16180	COG0438	transferase activity, transferring glycosyl groups
NUG20_16190	COG0438	transferase activity, transferring glycosyl groups
NUG20_16195	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
NUG20_16235	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
NUG20_16250	COG0745	RESPONSE REGULATOR receiver
NUG20_16260	COG0189	ligase activity
NUG20_16270	COG3511	phospholipase C
NUG20_16280	COG2201	protein-glutamate methylesterase activity
NUG20_16285	COG4566	intracellular signal transduction
NUG20_16290	COG4191	Histidine kinase
NUG20_16295	COG0783	Belongs to the Dps family
NUG20_16345	COG3273	potassium ion transport
NUG20_16345	COG0471	metal ion transport
NUG20_16360	COG0179	Fumarylacetoacetate (FAA) hydrolase
NUG20_16375	COG1609	Transcriptional regulator
NUG20_16385	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NUG20_16390	COG1115	amino acid carrier protein
NUG20_16405	COG0438	transferase activity, transferring glycosyl groups
NUG20_16410	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NUG20_16425	COG0308	aminopeptidase N
NUG20_16430	COG2895	sulfate adenylyltransferase (ATP) activity
NUG20_16430	COG0529	Catalyzes the synthesis of activated sulfate
NUG20_16440	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NUG20_16445	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NUG20_16450	COG0175	sulfate reduction
NUG20_16475	COG1393	Belongs to the ArsC family
NUG20_16480	COG0431	NADPH-dependent FMN reductase
NUG20_16525	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
NUG20_16535	COG0596	Alpha beta hydrolase
NUG20_16540	COG0583	DNA-binding transcription factor activity
NUG20_16545	COG3588	fructose-bisphosphate aldolase
NUG20_16550	COG0469	pyruvate kinase activity
NUG20_16580	COG3321	synthase
NUG20_16580	COG0604	alcohol dehydrogenase
NUG20_16590	COG4221	oxidoreductase activity
NUG20_16600	COG1902	pentaerythritol trinitrate reductase activity
NUG20_16615	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NUG20_16620	COG3047	cAMP biosynthetic process
NUG20_16625	COG3047	cAMP biosynthetic process
NUG20_16650	COG3591	Belongs to the peptidase S1B family
NUG20_16675	COG0640	Transcriptional regulator
NUG20_16685	COG0725	ABC transporter, periplasmic molybdate-binding protein
NUG20_16690	COG4149	molybdate abc transporter
NUG20_16695	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
NUG20_16710	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
NUG20_16725	COG1376	ErfK ybiS ycfS ynhG family protein
NUG20_16730	COG0739	heme binding
NUG20_16755	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NUG20_16760	COG1301	dicarboxylic acid transport
NUG20_16790	COG0714	Associated with various cellular activities
NUG20_16820	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
NUG20_16835	COG0372	Belongs to the citrate synthase family
NUG20_16840	COG0254	rRNA binding
NUG20_16850	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NUG20_16860	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NUG20_16865	COG1758	RNA polymerase activity
NUG20_16870	COG0194	GDP metabolic process
NUG20_16880	COG3712	iron ion homeostasis
NUG20_16910	COG2832	Protein of unknown function (DUF454)
NUG20_16920	COG0848	biopolymer transport protein
NUG20_16930	COG1561	YicC-like family, N-terminal region
NUG20_16935	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
NUG20_16940	COG0346	lactoylglutathione lyase activity
NUG20_16950	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NUG20_16965	COG0006	proline dipeptidase activity
NUG20_16970	COG1309	transcriptional regulator
NUG20_16975	COG3038	cytochrome b561
NUG20_16985	COG0006	proline dipeptidase activity
NUG20_16990	COG3079	Belongs to the UPF0149 family
NUG20_17020	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NUG20_17030	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NUG20_17045	COG1773	rubredoxin
NUG20_17050	COG0352	thiamine-phosphate diphosphorylase activity
NUG20_17065	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
NUG20_17070	COG2909	trisaccharide binding
NUG20_17075	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
NUG20_17080	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NUG20_17110	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NUG20_17115	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NUG20_17120	COG0346	lactoylglutathione lyase activity
NUG20_17135	COG0671	phosphoesterase, PA-phosphatase related
NUG20_17145	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
NUG20_17180	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
NUG20_17190	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
NUG20_17230	COG0840	transmembrane signaling receptor activity
NUG20_17235	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
NUG20_17240	COG0405	Gamma-glutamyltransferase
NUG20_17255	COG2207	Transcriptional regulator
NUG20_17260	COG2815	serine threonine protein kinase
NUG20_17260	COG0515	serine threonine protein kinase
NUG20_17310	COG0473	3-isopropylmalate dehydrogenase activity
NUG20_17325	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
NUG20_17330	COG1538	Outer membrane efflux protein
NUG20_17340	COG1519	Transferase
NUG20_17345	COG1560	Kdo2-lipid A biosynthetic process
NUG20_17370	COG0280	phosphate acetyltransferase
NUG20_17370	COG0281	malic enzyme
NUG20_17375	COG1301	dicarboxylic acid transport
NUG20_17385	COG4191	Histidine kinase
NUG20_17410	COG0642	Histidine kinase
NUG20_17425	COG2851	Citrate transporter
NUG20_17430	COG1028	Short-chain dehydrogenase reductase Sdr
NUG20_17445	COG1162	GTPase activity
NUG20_17450	COG0436	Aminotransferase
NUG20_17470	COG0726	polysaccharide deacetylase
NUG20_17475	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
NUG20_17490	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
NUG20_17495	COG0804	urea catabolic process
NUG20_17510	COG1307	EDD domain protein, DegV family
NUG20_17520	COG0697	spore germination
NUG20_17530	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NUG20_17550	COG3791	Glutathione-dependent formaldehyde-activating
NUG20_17555	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
NUG20_17570	COG2205	protein histidine kinase activity
NUG20_17575	COG3738	Protein conserved in bacteria
NUG20_17605	COG2207	Transcriptional regulator
NUG20_17640	COG4206	TonB-dependent receptor
NUG20_17655	COG3001	Fructosamine kinase
NUG20_17660	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
NUG20_17665	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
NUG20_17670	COG1609	Transcriptional regulator
NUG20_17675	COG0738	Major facilitator superfamily
NUG20_17680	COG2188	Transcriptional regulator
NUG20_17695	COG3250	beta-galactosidase activity
NUG20_17715	COG3525	Glycosyl hydrolase, family 20, catalytic domain
NUG20_17735	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NUG20_17745	COG4191	Histidine kinase
NUG20_17750	COG0784	Response regulator, receiver
NUG20_17755	COG2205	protein histidine kinase activity
NUG20_17755	COG2202	Pas domain
NUG20_17765	COG2823	Periplasmic or secreted lipoprotein
NUG20_17770	COG0673	inositol 2-dehydrogenase activity
NUG20_17775	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
NUG20_17785	COG1090	epimerase
NUG20_17815	COG1051	belongs to the nudix hydrolase family
NUG20_17815	COG1056	cytidyltransferase-related domain
NUG20_17845	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NUG20_17850	COG0321	lipoyl(octanoyl) transferase activity
NUG20_17865	COG1686	Belongs to the peptidase S11 family
NUG20_17870	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
NUG20_17875	COG2951	lytic endotransglycosylase activity
NUG20_17880	COG1012	belongs to the aldehyde dehydrogenase family
NUG20_17895	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
NUG20_17905	COG0772	Belongs to the SEDS family
NUG20_17910	COG0768	penicillin binding
NUG20_17920	COG1792	Involved in formation and maintenance of cell shape
NUG20_17925	COG1077	Cell shape determining protein MreB Mrl
NUG20_17930	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NUG20_17935	COG3284	Transcriptional regulator
NUG20_17945	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
NUG20_17955	COG2010	Cytochrome c
NUG20_17980	COG0508	dehydrogenase complex catalyzes the overall conversion of
NUG20_17980	COG0596	Alpha beta hydrolase
NUG20_17985	COG0308	aminopeptidase N
NUG20_17990	COG2226	methyltransferase
NUG20_18015	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
NUG20_18050	COG2832	Protein of unknown function (DUF454)
NUG20_18060	COG0436	Aminotransferase
NUG20_18065	COG1505	serine-type exopeptidase activity
NUG20_18080	COG1733	regulation of RNA biosynthetic process
NUG20_18095	COG0181	hydroxymethylbilane synthase activity
NUG20_18120	COG1335	isochorismatase
NUG20_18130	COG0745	RESPONSE REGULATOR receiver
NUG20_18140	COG0297	glycogen (starch) synthase activity
NUG20_18150	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NUG20_18185	COG0243	molybdopterin cofactor binding
NUG20_18190	COG2146	nitrite reductase [NAD(P)H] activity
NUG20_18195	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NUG20_18200	COG2223	nitrite transmembrane transporter activity
NUG20_18210	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NUG20_18245	COG1116	anion transmembrane transporter activity
NUG20_18245	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NUG20_18255	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NUG20_18255	COG1648	precorrin-2 dehydrogenase activity
NUG20_18275	COG2204	response regulator
NUG20_18280	COG4191	Histidine kinase
NUG20_18285	COG0028	Belongs to the TPP enzyme family
NUG20_18310	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NUG20_18320	COG1028	Short-chain dehydrogenase reductase Sdr
NUG20_18325	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
NUG20_18335	COG3685	Protein conserved in bacteria
NUG20_18340	COG3685	Protein conserved in bacteria
NUG20_18345	COG3546	catalase activity
NUG20_18370	COG0840	transmembrane signaling receptor activity
NUG20_18425	COG2271	Major facilitator Superfamily
NUG20_18430	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NUG20_18445	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NUG20_18445	COG2124	cytochrome p450
NUG20_18475	COG0840	transmembrane signaling receptor activity
NUG20_18485	COG1309	transcriptional regulator
NUG20_18510	COG3713	MltA-interacting MipA family protein
NUG20_18515	COG5002	protein histidine kinase activity
NUG20_18530	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NUG20_18550	COG1335	isochorismatase
NUG20_18555	COG0583	DNA-binding transcription factor activity
NUG20_18570	COG0024	Methionine aminopeptidase
NUG20_18580	COG2203	Gaf domain
NUG20_18580	COG4251	negative regulation of phosphorylation
NUG20_18580	COG5001	Diguanylate cyclase
NUG20_18580	COG3706	GGDEF domain
NUG20_18595	COG0300	oxidoreductase activity
NUG20_18605	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NUG20_18625	COG2207	Transcriptional regulator
NUG20_18655	COG1999	signal sequence binding
NUG20_18675	COG1733	regulation of RNA biosynthetic process
NUG20_18710	COG0811	peptide transport
NUG20_18715	COG2831	hemolysin activation secretion protein
NUG20_18755	COG4771	TonB-dependent receptor
NUG20_18760	COG1309	transcriptional regulator
NUG20_18795	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NUG20_18800	COG2181	nitrate reductase activity
NUG20_18805	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
NUG20_18810	COG1140	nitrate reductase beta subunit
NUG20_18815	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NUG20_18820	COG2223	nitrite transmembrane transporter activity
NUG20_18830	COG0314	molybdopterin synthase activity
NUG20_18840	COG0303	'Molybdopterin
NUG20_18845	COG0521	Mo-molybdopterin cofactor biosynthetic process
NUG20_18845	COG0315	cyclic pyranopterin monophosphate synthase activity
NUG20_18850	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NUG20_18860	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NUG20_18865	COG0840	transmembrane signaling receptor activity
NUG20_18880	COG0366	Alpha amylase catalytic
NUG20_18885	COG0366	Alpha amylase catalytic
NUG20_18890	COG0583	DNA-binding transcription factor activity
NUG20_18900	COG1028	Short-chain dehydrogenase reductase Sdr
NUG20_18915	COG1733	regulation of RNA biosynthetic process
NUG20_18920	COG3537	Alpha-1,2-mannosidase
NUG20_18925	COG1609	Transcriptional regulator
NUG20_18940	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NUG20_18945	COG1490	D-aminoacyl-tRNA deacylase activity
NUG20_18960	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NUG20_18995	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NUG20_19000	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NUG20_19000	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NUG20_19010	COG0242	peptide deformylase activity
NUG20_19015	COG1652	LysM domain
NUG20_19020	COG0758	DNA mediated transformation
NUG20_19035	COG1714	RDD family
NUG20_19040	COG1754	DNA topoisomerase type I activity
NUG20_19040	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NUG20_19045	COG0009	L-threonylcarbamoyladenylate synthase
NUG20_19060	COG1028	Short-chain dehydrogenase reductase Sdr
NUG20_19070	COG0616	signal peptide processing
NUG20_19075	COG0534	Mate efflux family protein
NUG20_19085	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NUG20_19095	COG1252	NADH dehydrogenase
NUG20_19100	COG2860	membrane
NUG20_19105	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NUG20_19110	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NUG20_19115	COG2201	protein-glutamate methylesterase activity
NUG20_19120	COG2177	Part of the ABC transporter FtsEX involved in
NUG20_19125	COG2884	Cell division ATP-binding protein ftsE
NUG20_19135	COG3118	belongs to the thioredoxin family
NUG20_19140	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NUG20_19160	COG0583	DNA-binding transcription factor activity
NUG20_19185	COG1652	LysM domain
NUG20_19200	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NUG20_19215	COG5383	Protein conserved in bacteria
NUG20_19255	COG3501	Rhs element vgr protein
NUG20_19255	COG3409	Peptidoglycan-binding domain 1 protein
NUG20_19285	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NUG20_19290	COG4771	TonB-dependent receptor
NUG20_19300	COG4948	Mandelate Racemase Muconate Lactonizing
NUG20_19310	COG0531	amino acid
NUG20_19340	COG2133	pyrroloquinoline quinone binding
NUG20_19355	COG2308	Evidence 4 Homologs of previously reported genes of
NUG20_19360	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NUG20_19380	COG1295	ribonuclease BN
NUG20_19385	COG0358	DNA primase activity
NUG20_19405	COG0840	transmembrane signaling receptor activity
NUG20_19410	COG0109	protoheme IX farnesyltransferase activity
NUG20_19415	COG1612	heme a metabolic process
NUG20_19435	COG1845	cytochrome c oxidase, subunit III
NUG20_19440	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
NUG20_19455	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
NUG20_19455	COG1565	acr, cog1565
NUG20_19470	COG1486	melibiose metabolic process
NUG20_19480	COG0531	amino acid
NUG20_19510	COG0793	Belongs to the peptidase S41A family
NUG20_19515	COG4942	peptidase
NUG20_19530	COG1064	alcohol dehydrogenase
NUG20_19565	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NUG20_19570	COG0739	heme binding
NUG20_19585	COG2807	transmembrane transport
NUG20_19595	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NUG20_19615	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NUG20_19635	COG4221	oxidoreductase activity
NUG20_19655	COG0583	DNA-binding transcription factor activity
NUG20_19660	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
NUG20_19660	COG2755	lipolytic protein G-D-S-L family
NUG20_19665	COG1166	arginine decarboxylase activity
NUG20_19680	COG2960	long-chain fatty acid transporting porin activity
NUG20_19685	COG0606	chelatase, subunit chli
NUG20_19705	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NUG20_19715	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NUG20_19740	COG1028	Short-chain dehydrogenase reductase Sdr
NUG20_19760	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NUG20_19775	COG3541	Predicted nucleotidyltransferase
NUG20_19785	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
NUG20_19815	COG0714	Associated with various cellular activities
NUG20_19880	COG0754	glutathionylspermidine amidase activity
NUG20_19885	COG5463	Belongs to the UPF0441 family
NUG20_19965	COG2814	Major facilitator Superfamily
NUG20_19985	COG1199	ATP-dependent helicase activity
NUG20_20010	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NUG20_20035	COG0028	Belongs to the TPP enzyme family
NUG20_20070	COG0625	glutathione transferase activity
NUG20_20085	COG0596	Alpha beta hydrolase
NUG20_20095	COG4555	ABC transporter
NUG20_20105	COG1476	TRANSCRIPTIONal
NUG20_20125	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
NUG20_20130	COG1028	Short-chain dehydrogenase reductase Sdr
NUG20_20135	COG2207	Transcriptional regulator
NUG20_20135	COG0662	Cupin 2, conserved barrel domain protein
NUG20_20140	COG0543	2 iron, 2 sulfur cluster binding
NUG20_20140	COG0633	Ferredoxin
NUG20_20145	COG1131	(ABC) transporter
NUG20_20150	COG0842	Transport permease protein
NUG20_20175	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NUG20_20180	COG0084	hydrolase, TatD family'
NUG20_20185	COG1643	Atp-dependent helicase
NUG20_20195	COG1187	pseudouridine synthase activity
NUG20_20210	COG2130	NADP-dependent
NUG20_20215	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NUG20_20245	COG1690	Belongs to the RtcB family
NUG20_20320	COG2948	multi-organism process
NUG20_20325	COG3504	Conjugal transfer protein
NUG20_20350	COG3451	type IV secretory pathway VirB4
NUG20_20360	COG3838	Conjugal transfer protein Trbc
NUG20_20365	COG4962	Type ii secretion system protein e
NUG20_20385	COG0583	DNA-binding transcription factor activity
NUG20_20390	COG0667	Aldo Keto reductase
NUG20_20395	COG1252	NADH dehydrogenase
NUG20_20405	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
NUG20_20420	COG4959	Type IV secretory pathway protease TraF
NUG20_20435	COG1192	Involved in chromosome partitioning
NUG20_20475	COG1475	DNA binding
NUG20_20495	COG1196	nuclear chromosome segregation
NUG20_20540	COG2224	Isocitrate lyase
NUG20_20545	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
NUG20_20550	COG0583	DNA-binding transcription factor activity
NUG20_20555	COG0475	glutathione-regulated potassium exporter activity
NUG20_20610	COG0681	Belongs to the peptidase S26 family
NUG20_20615	COG0339	signal peptide processing
NUG20_20620	COG1446	asparaginase
NUG20_20630	COG1595	DNA-templated transcription, initiation
NUG20_20660	COG0564	pseudouridine synthase activity
NUG20_20695	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NUG20_20710	COG0318	PFAM AMP-dependent synthetase and ligase
NUG20_20715	COG0727	PFAM Uncharacterised protein family (UPF0153)
NUG20_20720	COG0596	Alpha beta hydrolase
NUG20_20730	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NUG20_20740	COG0612	Peptidase, M16
NUG20_20750	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
NUG20_20765	COG0702	epimerase
NUG20_20780	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
NUG20_20785	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
NUG20_20825	COG0183	Belongs to the thiolase family
NUG20_20835	COG2032	superoxide dismutase activity
NUG20_20840	COG2032	superoxide dismutase activity
NUG20_20845	COG2204	response regulator
NUG20_20855	COG0004	ammonium transporteR
NUG20_20860	COG0347	Belongs to the P(II) protein family
NUG20_20865	COG0174	glutamine synthetase
NUG20_20870	COG1968	undecaprenyl-diphosphatase activity
NUG20_20875	COG1881	PFAM PEBP family protein
NUG20_20895	COG2050	protein possibly involved in aromatic compounds catabolism
NUG20_20900	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NUG20_20910	COG2062	phosphohistidine phosphatase, SixA
NUG20_20915	COG1192	Involved in chromosome partitioning
NUG20_20920	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NUG20_20980	COG0657	acetylesterase activity
NUG20_20985	COG4221	oxidoreductase activity
NUG20_21040	COG1111	helicase
NUG20_21040	COG1205	dead DEAH box helicase
NUG20_21065	COG2207	Transcriptional regulator
NUG20_21070	COG0667	Aldo Keto reductase
NUG20_21095	COG1028	Short-chain dehydrogenase reductase Sdr
NUG20_21120	COG0067	glutamate synthase
NUG20_21120	COG0070	glutamate synthase
NUG20_21120	COG0069	glutamate synthase activity
NUG20_21125	COG0493	'glutamate synthase
NUG20_21135	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
NUG20_21140	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
NUG20_21145	COG1803	Methylglyoxal synthase
NUG20_21190	COG3135	benzoate transporter
NUG20_21210	COG0676	glucose-6-phosphate 1-epimerase activity
NUG20_21220	COG0730	response to heat
NUG20_21240	COG0302	gtp cyclohydrolase
NUG20_21250	COG0477	Major facilitator Superfamily
NUG20_21260	COG0596	Alpha beta hydrolase
NUG20_21300	COG0537	adenosine 5'-monophosphoramidase activity
NUG20_21345	COG1028	Short-chain dehydrogenase reductase Sdr
NUG20_21370	COG1074	ATP-dependent DNA helicase activity
NUG20_21375	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
NUG20_21410	COG1127	ABC transporter
NUG20_21415	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
NUG20_21420	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
NUG20_21435	COG2853	Lipoprotein
NUG20_21445	COG0386	Belongs to the glutathione peroxidase family
NUG20_21455	COG1322	Protein conserved in bacteria
NUG20_21460	COG0625	glutathione transferase activity
NUG20_21465	COG0531	amino acid
NUG20_21475	COG2814	Major facilitator Superfamily
NUG20_21485	COG1929	Belongs to the glycerate kinase type-1 family
NUG20_21520	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
NUG20_21535	COG0671	phosphoesterase, PA-phosphatase related
NUG20_21580	COG3220	belongs to the UPF0276 family
NUG20_21590	COG1595	DNA-templated transcription, initiation
NUG20_21600	COG1752	Esterase of the alpha-beta hydrolase superfamily
NUG20_21610	COG1522	sequence-specific DNA binding
NUG20_21615	COG3186	Phenylalanine-4-hydroxylase
NUG20_21625	COG2755	lipolytic protein G-D-S-L family
NUG20_21635	COG1028	Short-chain dehydrogenase reductase Sdr
NUG20_21640	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
NUG20_21650	COG3507	Belongs to the glycosyl hydrolase 43 family
NUG20_21665	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
NUG20_21675	COG2755	lipolytic protein G-D-S-L family
NUG20_21675	COG0657	acetylesterase activity
NUG20_21715	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
NUG20_21725	COG2815	serine threonine protein kinase
NUG20_21725	COG0515	serine threonine protein kinase
NUG20_21735	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
NUG20_21765	COG1119	ATPase activity
NUG20_21780	COG1574	metal-dependent hydrolase with the TIM-barrel fold
NUG20_21790	COG1335	isochorismatase
NUG20_21810	COG1733	regulation of RNA biosynthetic process
NUG20_21830	COG0706	membrane insertase activity