locus-tag	class	description
NUG21_00010	COG0592	DNA-directed DNA polymerase activity
NUG21_00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NUG21_00020	COG0187	DNA topoisomerase II activity
NUG21_00025	COG1266	CAAX protease self-immunity
NUG21_00030	COG0501	Belongs to the peptidase M48B family
NUG21_00075	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NUG21_00090	COG0655	NAD(P)H dehydrogenase (quinone) activity
NUG21_00130	COG4772	TonB-dependent receptor
NUG21_00140	COG3284	Transcriptional regulator
NUG21_00145	COG1012	belongs to the aldehyde dehydrogenase family
NUG21_00175	COG1304	FMN binding
NUG21_00180	COG2186	Transcriptional regulator
NUG21_00190	COG4585	Histidine kinase
NUG21_00195	COG2197	response regulator
NUG21_00290	COG4771	TonB-dependent receptor
NUG21_00295	COG4774	siderophore transport
NUG21_00295	COG1629	transport
NUG21_00320	COG2272	Belongs to the type-B carboxylesterase lipase family
NUG21_00325	COG0657	acetylesterase activity
NUG21_00325	COG2755	lipolytic protein G-D-S-L family
NUG21_00335	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
NUG21_00350	COG1609	Transcriptional regulator
NUG21_00365	COG1028	Short-chain dehydrogenase reductase Sdr
NUG21_00395	COG3186	Phenylalanine-4-hydroxylase
NUG21_00400	COG1522	sequence-specific DNA binding
NUG21_00430	COG2842	Transposition protein
NUG21_00495	COG5566	PFAM Mor transcription activator
NUG21_00505	COG1196	nuclear chromosome segregation
NUG21_00505	COG0741	lytic transglycosylase activity
NUG21_00505	COG0739	heme binding
NUG21_00540	COG4373	Mu-like prophage FluMu protein gp28
NUG21_00545	COG4383	Mu-like prophage protein gp29
NUG21_00570	COG4397	Mu-like prophage major head subunit gpT
NUG21_00655	COG1752	Esterase of the alpha-beta hydrolase superfamily
NUG21_00675	COG0861	Integral membrane protein TerC family
NUG21_00680	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
NUG21_00695	COG1929	Belongs to the glycerate kinase type-1 family
NUG21_00710	COG0531	amino acid
NUG21_00715	COG4566	intracellular signal transduction
NUG21_00720	COG4191	Histidine kinase
NUG21_00725	COG1285	pathogenesis
NUG21_00735	COG1322	Protein conserved in bacteria
NUG21_00740	COG0386	Belongs to the glutathione peroxidase family
NUG21_00750	COG2853	Lipoprotein
NUG21_00765	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
NUG21_00770	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
NUG21_00775	COG1127	ABC transporter
NUG21_00810	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
NUG21_00815	COG1074	ATP-dependent DNA helicase activity
NUG21_00820	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NUG21_00825	COG1028	Short-chain dehydrogenase reductase Sdr
NUG21_00880	COG0840	transmembrane signaling receptor activity
NUG21_00890	COG0477	Major facilitator Superfamily
NUG21_00895	COG0302	gtp cyclohydrolase
NUG21_00925	COG2951	lytic endotransglycosylase activity
NUG21_00945	COG3135	benzoate transporter
NUG21_00985	COG1803	Methylglyoxal synthase
NUG21_00990	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
NUG21_00995	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
NUG21_01000	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
NUG21_01005	COG0493	'glutamate synthase
NUG21_01010	COG0069	glutamate synthase activity
NUG21_01010	COG0067	glutamate synthase
NUG21_01010	COG0070	glutamate synthase
NUG21_01035	COG1028	Short-chain dehydrogenase reductase Sdr
NUG21_01080	COG1111	helicase
NUG21_01080	COG1205	dead DEAH box helicase
NUG21_01085	COG1272	protein, Hemolysin III
NUG21_01115	COG2271	Major facilitator Superfamily
NUG21_01125	COG0657	acetylesterase activity
NUG21_01160	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NUG21_01165	COG1192	Involved in chromosome partitioning
NUG21_01170	COG2062	phosphohistidine phosphatase, SixA
NUG21_01180	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NUG21_01185	COG2050	protein possibly involved in aromatic compounds catabolism
NUG21_01210	COG1968	undecaprenyl-diphosphatase activity
NUG21_01215	COG0174	glutamine synthetase
NUG21_01220	COG0347	Belongs to the P(II) protein family
NUG21_01225	COG0004	ammonium transporteR
NUG21_01230	COG3852	Histidine kinase
NUG21_01235	COG2204	response regulator
NUG21_01240	COG2032	superoxide dismutase activity
NUG21_01245	COG2032	superoxide dismutase activity
NUG21_01280	COG0456	acetyltransferase
NUG21_01295	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
NUG21_01300	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
NUG21_01310	COG3226	Transcriptional regulator
NUG21_01330	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
NUG21_01340	COG0612	Peptidase, M16
NUG21_01350	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NUG21_01360	COG0596	Alpha beta hydrolase
NUG21_01370	COG0727	PFAM Uncharacterised protein family (UPF0153)
NUG21_01375	COG0318	PFAM AMP-dependent synthetase and ligase
NUG21_01380	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NUG21_01410	COG0564	pseudouridine synthase activity
NUG21_01440	COG1595	DNA-templated transcription, initiation
NUG21_01450	COG1446	asparaginase
NUG21_01455	COG0339	signal peptide processing
NUG21_01465	COG0681	Belongs to the peptidase S26 family
NUG21_01505	COG0583	DNA-binding transcription factor activity
NUG21_01510	COG0583	DNA-binding transcription factor activity
NUG21_01515	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
NUG21_01520	COG2224	Isocitrate lyase
NUG21_01525	COG3706	GGDEF domain
NUG21_01545	COG4297	protein containing double-stranded beta helix domain
NUG21_01550	COG0659	secondary active sulfate transmembrane transporter activity
NUG21_01580	COG1024	Enoyl-CoA hydratase
NUG21_01585	COG1022	Amp-dependent synthetase and ligase
NUG21_01595	COG2814	Major facilitator Superfamily
NUG21_01660	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
NUG21_01670	COG3485	protocatechuate 3,4-dioxygenase
NUG21_01675	COG3485	protocatechuate 3,4-dioxygenase
NUG21_01680	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NUG21_01685	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NUG21_01690	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NUG21_01695	COG1414	Transcriptional regulator
NUG21_01700	COG2130	NADP-dependent
NUG21_01715	COG1187	pseudouridine synthase activity
NUG21_01725	COG1643	Atp-dependent helicase
NUG21_01730	COG0084	hydrolase, TatD family'
NUG21_01745	COG2885	chlorophyll binding
NUG21_01745	COG3047	cAMP biosynthetic process
NUG21_01820	COG0842	Transport permease protein
NUG21_01825	COG1131	(ABC) transporter
NUG21_01830	COG0633	Ferredoxin
NUG21_01830	COG0543	2 iron, 2 sulfur cluster binding
NUG21_01840	COG1476	TRANSCRIPTIONal
NUG21_01850	COG4555	ABC transporter
NUG21_01875	COG0625	glutathione transferase activity
NUG21_01935	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NUG21_01960	COG1199	ATP-dependent helicase activity
NUG21_02025	COG3511	phospholipase C
NUG21_02035	COG0628	permease
NUG21_02105	COG0754	glutathionylspermidine amidase activity
NUG21_02125	COG0714	Associated with various cellular activities
NUG21_02160	COG1522	sequence-specific DNA binding
NUG21_02165	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
NUG21_02170	COG4106	trans-aconitate 2-methyltransferase activity
NUG21_02175	COG3420	alginic acid biosynthetic process
NUG21_02185	COG0710	3-dehydroquinate dehydratase activity
NUG21_02200	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NUG21_02205	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NUG21_02220	COG0657	acetylesterase activity
NUG21_02235	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NUG21_02250	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NUG21_02260	COG1028	Short-chain dehydrogenase reductase Sdr
NUG21_02275	COG0156	8-amino-7-oxononanoate synthase activity
NUG21_02280	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NUG21_02285	COG1040	competence protein
NUG21_02305	COG0606	chelatase, subunit chli
NUG21_02310	COG2960	long-chain fatty acid transporting porin activity
NUG21_02325	COG1166	arginine decarboxylase activity
NUG21_02340	COG0583	DNA-binding transcription factor activity
NUG21_02375	COG4221	oxidoreductase activity
NUG21_02390	COG2003	Belongs to the UPF0758 family
NUG21_02395	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NUG21_02405	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NUG21_02415	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NUG21_02420	COG0708	Exodeoxyribonuclease III
NUG21_02425	COG2211	Major facilitator Superfamily
NUG21_02440	COG0739	heme binding
NUG21_02445	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NUG21_02475	COG1064	alcohol dehydrogenase
NUG21_02480	COG2234	aminopeptidase activity
NUG21_02490	COG4942	peptidase
NUG21_02495	COG0793	Belongs to the peptidase S41A family
NUG21_02500	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NUG21_02530	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
NUG21_02545	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
NUG21_02580	COG0840	transmembrane signaling receptor activity
NUG21_02600	COG0358	DNA primase activity
NUG21_02605	COG1295	ribonuclease BN
NUG21_02610	COG1610	YqeY-like protein
NUG21_02625	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NUG21_02630	COG0668	transmembrane transport
NUG21_02635	COG2308	Evidence 4 Homologs of previously reported genes of
NUG21_02650	COG2133	pyrroloquinoline quinone binding
NUG21_02670	COG0531	amino acid
NUG21_02695	COG1609	Transcriptional regulator
NUG21_02720	COG1070	Carbohydrate kinase
NUG21_02730	COG1472	Belongs to the glycosyl hydrolase 3 family
NUG21_02740	COG3661	Belongs to the glycosyl hydrolase 67 family
NUG21_02755	COG1472	Belongs to the glycosyl hydrolase 3 family
NUG21_02770	COG4948	Mandelate Racemase Muconate Lactonizing
NUG21_02780	COG4771	TonB-dependent receptor
NUG21_02785	COG3023	N-Acetylmuramoyl-L-alanine amidase
NUG21_02810	COG3501	Rhs element vgr protein
NUG21_02810	COG3409	Peptidoglycan-binding domain 1 protein
NUG21_02845	COG5383	Protein conserved in bacteria
NUG21_02850	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NUG21_02855	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NUG21_02890	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NUG21_02960	COG0708	Exodeoxyribonuclease III
NUG21_02965	COG1418	mRNA catabolic process
NUG21_02970	COG4807	Protein conserved in bacteria
NUG21_02990	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
NUG21_03020	COG1028	Short-chain dehydrogenase reductase Sdr
NUG21_03025	COG0179	Fumarylacetoacetate (FAA) hydrolase
NUG21_03030	COG4948	Mandelate Racemase Muconate Lactonizing
NUG21_03035	COG3254	rhamnose metabolic process
NUG21_03040	COG0738	Major facilitator superfamily
NUG21_03045	COG1414	Transcriptional regulator
NUG21_03110	COG1802	Transcriptional regulator
NUG21_03140	COG0604	alcohol dehydrogenase
NUG21_03145	COG1196	nuclear chromosome segregation
NUG21_03145	COG3264	Mechanosensitive ion channel
NUG21_03170	COG2354	Protein conserved in bacteria
NUG21_03195	COG0702	epimerase
NUG21_03200	COG1028	Short-chain dehydrogenase reductase Sdr
NUG21_03210	COG0513	Belongs to the DEAD box helicase family
NUG21_03255	COG3483	tryptophan 2,3-dioxygenase activity
NUG21_03260	COG3104	oligopeptide transport
NUG21_03280	COG2852	Protein conserved in bacteria
NUG21_03285	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
NUG21_03305	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NUG21_03310	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NUG21_03315	COG1473	amidohydrolase
NUG21_03325	COG1652	LysM domain
NUG21_03355	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NUG21_03360	COG3118	belongs to the thioredoxin family
NUG21_03370	COG2884	Cell division ATP-binding protein ftsE
NUG21_03375	COG2177	Part of the ABC transporter FtsEX involved in
NUG21_03380	COG2201	protein-glutamate methylesterase activity
NUG21_03385	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NUG21_03390	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NUG21_03395	COG2860	membrane
NUG21_03400	COG1252	NADH dehydrogenase
NUG21_03410	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NUG21_03420	COG0534	Mate efflux family protein
NUG21_03425	COG0616	signal peptide processing
NUG21_03435	COG1028	Short-chain dehydrogenase reductase Sdr
NUG21_03450	COG0009	L-threonylcarbamoyladenylate synthase
NUG21_03455	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NUG21_03455	COG1754	DNA topoisomerase type I activity
NUG21_03460	COG1714	RDD family
NUG21_03475	COG0758	DNA mediated transformation
NUG21_03480	COG1652	LysM domain
NUG21_03485	COG0242	peptide deformylase activity
NUG21_03495	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NUG21_03495	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NUG21_03500	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NUG21_03535	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NUG21_03550	COG1490	D-aminoacyl-tRNA deacylase activity
NUG21_03555	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NUG21_03570	COG1609	Transcriptional regulator
NUG21_03575	COG3537	Alpha-1,2-mannosidase
NUG21_03580	COG0366	Alpha amylase catalytic
NUG21_03585	COG0366	Alpha amylase catalytic
NUG21_03695	COG4974	Belongs to the 'phage' integrase family
NUG21_03765	COG0024	Methionine aminopeptidase
NUG21_03770	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NUG21_03775	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NUG21_03785	COG5002	protein histidine kinase activity
NUG21_03790	COG3038	cytochrome b561
NUG21_03795	COG1309	transcriptional regulator
NUG21_03815	COG2124	cytochrome p450
NUG21_03815	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NUG21_03830	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NUG21_03835	COG2271	Major facilitator Superfamily
NUG21_03860	COG0840	transmembrane signaling receptor activity
NUG21_03870	COG3546	catalase activity
NUG21_03875	COG3685	Protein conserved in bacteria
NUG21_03880	COG3685	Protein conserved in bacteria
NUG21_03885	COG1028	Short-chain dehydrogenase reductase Sdr
NUG21_03895	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NUG21_03920	COG0028	Belongs to the TPP enzyme family
NUG21_03950	COG1648	precorrin-2 dehydrogenase activity
NUG21_03950	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NUG21_03980	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NUG21_03990	COG0297	glycogen (starch) synthase activity
NUG21_04000	COG2204	response regulator
NUG21_04010	COG1335	isochorismatase
NUG21_04030	COG0181	hydroxymethylbilane synthase activity
NUG21_04045	COG1733	regulation of RNA biosynthetic process
NUG21_04060	COG1505	serine-type exopeptidase activity
NUG21_04070	COG0436	Aminotransferase
NUG21_04080	COG2832	Protein of unknown function (DUF454)
NUG21_04090	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NUG21_04110	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
NUG21_04115	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
NUG21_04135	COG2226	methyltransferase
NUG21_04140	COG0308	aminopeptidase N
NUG21_04175	COG2010	Cytochrome c
NUG21_04195	COG3284	Transcriptional regulator
NUG21_04200	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NUG21_04205	COG1077	Cell shape determining protein MreB Mrl
NUG21_04210	COG1792	Involved in formation and maintenance of cell shape
NUG21_04225	COG0772	Belongs to the SEDS family
NUG21_04235	COG5434	Belongs to the glycosyl hydrolase 28 family
NUG21_04240	COG2951	lytic endotransglycosylase activity
NUG21_04250	COG1686	Belongs to the peptidase S11 family
NUG21_04260	COG2921	Belongs to the UPF0250 family
NUG21_04285	COG0583	DNA-binding transcription factor activity
NUG21_04300	COG1051	belongs to the nudix hydrolase family
NUG21_04300	COG1056	cytidyltransferase-related domain
NUG21_04330	COG1090	epimerase
NUG21_04340	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
NUG21_04345	COG0673	inositol 2-dehydrogenase activity
NUG21_04350	COG2823	Periplasmic or secreted lipoprotein
NUG21_04360	COG2205	protein histidine kinase activity
NUG21_04365	COG0784	Response regulator, receiver
NUG21_04370	COG4191	Histidine kinase
NUG21_04380	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NUG21_04385	COG1028	Short-chain dehydrogenase reductase Sdr
NUG21_04400	COG4305	rare lipoprotein A
NUG21_04420	COG3250	beta-galactosidase activity
NUG21_04435	COG2188	Transcriptional regulator
NUG21_04440	COG0738	Major facilitator superfamily
NUG21_04445	COG1609	Transcriptional regulator
NUG21_04450	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
NUG21_04455	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
NUG21_04505	COG0218	Necessary for normal cell division and for the maintenance of normal septation
NUG21_04515	COG2207	Transcriptional regulator
NUG21_04560	COG0393	Putative heavy-metal-binding
NUG21_04565	COG2205	protein histidine kinase activity
NUG21_04580	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
NUG21_04585	COG3791	Glutathione-dependent formaldehyde-activating
NUG21_04600	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NUG21_04610	COG0697	spore germination
NUG21_04620	COG1307	EDD domain protein, DegV family
NUG21_04640	COG0804	urea catabolic process
NUG21_04645	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
NUG21_04655	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
NUG21_04660	COG0726	polysaccharide deacetylase
NUG21_04680	COG0436	Aminotransferase
NUG21_04685	COG1162	GTPase activity
NUG21_04715	COG2211	Major facilitator Superfamily
NUG21_04725	COG1028	Short-chain dehydrogenase reductase Sdr
NUG21_04730	COG2851	Citrate transporter
NUG21_04745	COG0642	Histidine kinase
NUG21_04755	COG2205	protein histidine kinase activity
NUG21_04755	COG3292	Two component regulator propeller
NUG21_04755	COG2205	protein histidine kinase activity
NUG21_04755	COG3292	Two component regulator propeller
NUG21_04755	COG0745	RESPONSE REGULATOR receiver
NUG21_04755	COG0745	RESPONSE REGULATOR receiver
NUG21_04770	COG4191	Histidine kinase
NUG21_04780	COG1301	dicarboxylic acid transport
NUG21_04785	COG0280	phosphate acetyltransferase
NUG21_04785	COG0281	malic enzyme
NUG21_04815	COG1519	Transferase
NUG21_04820	COG1538	Outer membrane efflux protein
NUG21_04825	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
NUG21_04840	COG0473	3-isopropylmalate dehydrogenase activity
NUG21_04845	COG0066	3-isopropylmalate dehydratase activity
NUG21_04855	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NUG21_04860	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NUG21_04880	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NUG21_04885	COG0405	Gamma-glutamyltransferase
NUG21_04895	COG0840	transmembrane signaling receptor activity
NUG21_04900	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
NUG21_04920	COG0823	Involved in the tonB-independent uptake of proteins
NUG21_04920	COG1506	peptidase
NUG21_04920	COG4946	Tricorn protease homolog
NUG21_04940	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
NUG21_04950	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
NUG21_04975	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
NUG21_04990	COG0586	Pfam SNARE associated Golgi protein
NUG21_05015	COG0346	lactoylglutathione lyase activity
NUG21_05020	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NUG21_05030	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
NUG21_05035	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
NUG21_05045	COG1773	rubredoxin
NUG21_05060	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NUG21_05070	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NUG21_05100	COG3079	Belongs to the UPF0149 family
NUG21_05105	COG0006	proline dipeptidase activity
NUG21_05115	COG0006	proline dipeptidase activity
NUG21_05130	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NUG21_05140	COG0346	lactoylglutathione lyase activity
NUG21_05145	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
NUG21_05150	COG1561	YicC-like family, N-terminal region
NUG21_05155	COG0194	GDP metabolic process
NUG21_05160	COG1758	RNA polymerase activity
NUG21_05165	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NUG21_05175	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NUG21_05185	COG0254	rRNA binding
NUG21_05200	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
NUG21_05230	COG0714	Associated with various cellular activities
NUG21_05260	COG1301	dicarboxylic acid transport
NUG21_05265	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NUG21_05325	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
NUG21_05330	COG4149	molybdate abc transporter
NUG21_05335	COG0725	ABC transporter, periplasmic molybdate-binding protein
NUG21_05345	COG0640	Transcriptional regulator
NUG21_05380	COG3047	cAMP biosynthetic process
NUG21_05385	COG3047	cAMP biosynthetic process
NUG21_05390	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NUG21_05425	COG0469	pyruvate kinase activity
NUG21_05430	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
NUG21_05435	COG3588	fructose-bisphosphate aldolase
NUG21_05460	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
NUG21_05490	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NUG21_05490	COG1648	precorrin-2 dehydrogenase activity
NUG21_05495	COG0583	DNA-binding transcription factor activity
NUG21_05505	COG5002	protein histidine kinase activity
NUG21_05530	COG0175	sulfate reduction
NUG21_05535	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NUG21_05540	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NUG21_05545	COG0175	sulfate reduction
NUG21_05550	COG0529	Catalyzes the synthesis of activated sulfate
NUG21_05550	COG2895	sulfate adenylyltransferase (ATP) activity
NUG21_05555	COG0308	aminopeptidase N
NUG21_05565	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NUG21_05570	COG0438	transferase activity, transferring glycosyl groups
NUG21_05605	COG1609	Transcriptional regulator
NUG21_05620	COG0179	Fumarylacetoacetate (FAA) hydrolase
NUG21_05635	COG0471	metal ion transport
NUG21_05635	COG3273	potassium ion transport
NUG21_05640	COG0220	tRNA (guanine-N7-)-methyltransferase activity
NUG21_05665	COG0583	DNA-binding transcription factor activity
NUG21_05670	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NUG21_05680	COG3511	phospholipase C
NUG21_05690	COG0189	ligase activity
NUG21_05695	COG0745	RESPONSE REGULATOR receiver
NUG21_05710	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
NUG21_05730	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NUG21_05745	COG0045	succinate-CoA ligase (ADP-forming) activity
NUG21_05750	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
NUG21_05760	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
NUG21_05760	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NUG21_05765	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
NUG21_05770	COG1262	PFAM Formylglycine-generating sulfatase enzyme
NUG21_05785	COG1125	glycine betaine transport
NUG21_05795	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NUG21_05800	COG0564	pseudouridine synthase activity
NUG21_05820	COG0840	transmembrane signaling receptor activity
NUG21_05825	COG4993	Dehydrogenase
NUG21_05835	COG3387	PFAM Glycoside hydrolase 15-related
NUG21_05845	COG4771	TonB-dependent receptor
NUG21_05855	COG0454	-acetyltransferase
NUG21_05875	COG0542	response to heat
NUG21_05890	COG0583	DNA-binding transcription factor activity
NUG21_05895	COG1289	transmembrane transporter activity
NUG21_05900	COG1028	Short-chain dehydrogenase reductase Sdr
NUG21_05905	COG1733	regulation of RNA biosynthetic process
NUG21_05915	COG2223	nitrite transmembrane transporter activity
NUG21_05930	COG0019	diaminopimelate decarboxylase activity
NUG21_05935	COG4264	IucA IucC family
NUG21_05940	COG2814	Major facilitator Superfamily
NUG21_05945	COG4264	IucA IucC family
NUG21_05955	COG4772	TonB-dependent receptor
NUG21_05965	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NUG21_05965	COG4651	solute:proton antiporter activity
NUG21_05995	COG0488	(ABC) transporter
NUG21_06020	COG2755	lipolytic protein G-D-S-L family
NUG21_06020	COG0657	acetylesterase activity
NUG21_06050	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NUG21_06090	COG0632	four-way junction helicase activity
NUG21_06095	COG3158	transport of potassium into the cell
NUG21_06105	COG0824	Thioesterase
NUG21_06115	COG0848	biopolymer transport protein
NUG21_06130	COG2885	chlorophyll binding
NUG21_06140	COG0602	queuosine metabolic process
NUG21_06145	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NUG21_06180	COG0514	ATP-dependent DNA helicase (RecQ)
NUG21_06185	COG0783	Belongs to the Dps family
NUG21_06190	COG1643	Atp-dependent helicase
NUG21_06225	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NUG21_06235	COG0463	Glycosyl transferase, family 2
NUG21_06240	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NUG21_06250	COG1199	ATP-dependent helicase activity
NUG21_06275	COG0189	ligase activity
NUG21_06290	COG0835	chemotaxis
NUG21_06295	COG0840	transmembrane signaling receptor activity
NUG21_06305	COG2201	protein-glutamate methylesterase activity
NUG21_06320	COG1446	asparaginase
NUG21_06350	COG1733	regulation of RNA biosynthetic process
NUG21_06355	COG0604	alcohol dehydrogenase
NUG21_06385	COG3537	Alpha-1,2-mannosidase
NUG21_06395	COG1486	melibiose metabolic process
NUG21_06405	COG0531	amino acid
NUG21_06420	COG1472	Belongs to the glycosyl hydrolase 3 family
NUG21_06430	COG3525	Glycosyl hydrolase, family 20, catalytic domain
NUG21_06435	COG3858	chitin binding
NUG21_06435	COG1388	LysM domain
NUG21_06450	COG0837	glucose binding
NUG21_06455	COG1385	rRNA (uridine-N3-)-methyltransferase activity
NUG21_06465	COG0494	nUDIX hydrolase
NUG21_06470	COG1218	3'(2'),5'-bisphosphate nucleotidase
NUG21_06475	COG3956	TIGRFAM MazG family protein
NUG21_06490	COG0330	HflC and HflK could
NUG21_06500	COG0404	The glycine cleavage system catalyzes the degradation of glycine
NUG21_06540	COG1960	acyl-CoA dehydrogenase activity
NUG21_06550	COG1309	transcriptional regulator
NUG21_06565	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NUG21_06570	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NUG21_06575	COG0463	Glycosyl transferase, family 2
NUG21_06580	COG0517	IMP dehydrogenase activity
NUG21_06590	COG1272	protein, Hemolysin III
NUG21_06595	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NUG21_06600	COG0739	heme binding
NUG21_06605	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NUG21_06610	COG0626	cystathionine gamma-synthase activity
NUG21_06615	COG0460	homoserine dehydrogenase
NUG21_06615	COG0527	aspartate kinase activity
NUG21_06630	COG2267	carboxylic ester hydrolase activity
NUG21_06640	COG1760	l-serine dehydratase
NUG21_06650	COG0625	glutathione transferase activity
NUG21_06660	COG3038	cytochrome b561
NUG21_06665	COG2353	YceI-like domain
NUG21_06680	COG0477	Major facilitator Superfamily
NUG21_06685	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
NUG21_06695	COG1609	Transcriptional regulator
NUG21_06695	COG2207	Transcriptional regulator
NUG21_06710	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NUG21_06740	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NUG21_06785	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NUG21_06825	COG0519	Catalyzes the synthesis of GMP from XMP
NUG21_06835	COG1678	Uncharacterized ACR, COG1678
NUG21_06840	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NUG21_06860	COG0840	transmembrane signaling receptor activity
NUG21_06865	COG0840	transmembrane signaling receptor activity
NUG21_06875	COG1113	amino acid transport
NUG21_06895	COG2239	Acts as a magnesium transporter
NUG21_06900	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NUG21_06905	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NUG21_06915	COG1660	Displays ATPase and GTPase activities
NUG21_06925	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NUG21_06940	COG1137	ATPase activity
NUG21_06955	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
NUG21_06990	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NUG21_07005	COG0628	permease
NUG21_07015	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
NUG21_07020	COG3178	'Phosphotransferase
NUG21_07050	COG1477	protein flavinylation
NUG21_07155	COG1981	membrane
NUG21_07180	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NUG21_07185	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NUG21_07195	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NUG21_07205	COG0750	zinc metalloprotease
NUG21_07210	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
NUG21_07215	COG0575	Belongs to the CDS family
NUG21_07220	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NUG21_07230	COG0528	UMP kinase activity
NUG21_07235	COG3706	GGDEF domain
NUG21_07245	COG0052	Belongs to the universal ribosomal protein uS2 family
NUG21_07285	COG0024	Methionine aminopeptidase
NUG21_07290	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
NUG21_07310	COG1393	Belongs to the ArsC family
NUG21_07320	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NUG21_07325	COG0367	asparagine synthase
NUG21_07385	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
NUG21_07440	COG1566	PFAM secretion protein HlyD family protein
NUG21_07445	COG2814	Major facilitator Superfamily
NUG21_07480	COG0557	exoribonuclease II activity
NUG21_07490	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NUG21_07495	COG3706	GGDEF domain
NUG21_07505	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NUG21_07525	COG0704	Plays a role in the regulation of phosphate uptake
NUG21_07535	COG0581	inorganic phosphate transmembrane transporter activity
NUG21_07540	COG0573	inorganic phosphate transmembrane transporter activity
NUG21_07545	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
NUG21_07550	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
NUG21_07570	COG0659	secondary active sulfate transmembrane transporter activity
NUG21_07575	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NUG21_07585	COG1024	Enoyl-CoA hydratase
NUG21_07630	COG0488	(ABC) transporter
NUG21_07635	COG0300	oxidoreductase activity
NUG21_07640	COG2207	Transcriptional regulator
NUG21_07645	COG0116	Belongs to the methyltransferase superfamily
NUG21_07645	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
NUG21_07655	COG4999	Histidine kinase
NUG21_07655	COG2205	protein histidine kinase activity
NUG21_07655	COG3437	response regulator, receiver
NUG21_07655	COG3850	Histidine kinase
NUG21_07660	COG2733	membrane
NUG21_07675	COG0686	Belongs to the AlaDH PNT family
NUG21_07680	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NUG21_07685	COG1396	sequence-specific DNA binding
NUG21_07685	COG1917	Cupin 2, conserved barrel domain protein
NUG21_07690	COG1012	belongs to the aldehyde dehydrogenase family
NUG21_07705	COG2223	nitrite transmembrane transporter activity
NUG21_07715	COG0243	molybdopterin cofactor binding
NUG21_07730	COG0477	Major facilitator Superfamily
NUG21_07740	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NUG21_07745	COG0174	glutamine synthetase
NUG21_07750	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
NUG21_07755	COG0174	glutamine synthetase
NUG21_07785	COG3842	ATPase activity
NUG21_07790	COG1176	ABC-type spermidine putrescine transport system, permease component I
NUG21_07795	COG1177	transmembrane transport
NUG21_07800	COG1012	belongs to the aldehyde dehydrogenase family
NUG21_07815	COG4535	Mg2 and Co2 transporter CorC
NUG21_07825	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NUG21_07835	COG1702	phosphate starvation-inducible protein PhoH
NUG21_07855	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NUG21_07875	COG0741	lytic transglycosylase activity
NUG21_07880	COG0723	plastoquinol--plastocyanin reductase activity
NUG21_07885	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
NUG21_07890	COG2857	Cytochrome c1
NUG21_07895	COG0625	glutathione transferase activity
NUG21_07900	COG2969	positive regulation of protein catabolic process
NUG21_07940	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
NUG21_07945	COG1028	Short-chain dehydrogenase reductase Sdr
NUG21_07950	COG2095	MarC family integral membrane protein
NUG21_07960	COG1611	Belongs to the LOG family
NUG21_07965	COG3275	phosphorelay sensor kinase activity
NUG21_08010	COG0556	nucleotide-excision repair
NUG21_08025	COG3505	Type IV secretory pathway VirD4
NUG21_08085	COG0366	Alpha amylase catalytic
NUG21_08095	COG1082	Xylose isomerase domain protein TIM barrel
NUG21_08125	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NUG21_08135	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NUG21_08140	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NUG21_08195	COG0438	transferase activity, transferring glycosyl groups
NUG21_08200	COG0438	transferase activity, transferring glycosyl groups
NUG21_08205	COG2244	polysaccharide biosynthetic process
NUG21_08210	COG0438	transferase activity, transferring glycosyl groups
NUG21_08240	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NUG21_08250	COG1960	acyl-CoA dehydrogenase activity
NUG21_08255	COG2197	response regulator
NUG21_08265	COG2815	serine threonine protein kinase
NUG21_08265	COG0515	serine threonine protein kinase
NUG21_08280	COG1404	Belongs to the peptidase S8 family
NUG21_08285	COG1566	PFAM secretion protein HlyD family protein
NUG21_08320	COG3040	lipid binding
NUG21_08330	COG1570	exodeoxyribonuclease VII activity
NUG21_08335	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NUG21_08340	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NUG21_08340	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
NUG21_08345	COG0802	atpase or kinase
NUG21_08350	COG0860	N-Acetylmuramoyl-L-alanine amidase
NUG21_08375	COG1028	Short-chain dehydrogenase reductase Sdr
NUG21_08395	COG2081	HI0933 family
NUG21_08400	COG4681	YaeQ
NUG21_08410	COG0625	glutathione transferase activity
NUG21_08430	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NUG21_08440	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NUG21_08450	COG0513	Belongs to the DEAD box helicase family
NUG21_08455	COG0488	(ABC) transporter
NUG21_08470	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NUG21_08480	COG1472	Belongs to the glycosyl hydrolase 3 family
NUG21_08520	COG0339	signal peptide processing
NUG21_08525	COG0386	Belongs to the glutathione peroxidase family
NUG21_08555	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NUG21_08570	COG0625	glutathione transferase activity
NUG21_08610	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
NUG21_08615	COG5001	Diguanylate cyclase
NUG21_08615	COG2203	Gaf domain
NUG21_08615	COG3706	GGDEF domain
NUG21_08615	COG4251	negative regulation of phosphorylation
NUG21_08620	COG0084	hydrolase, TatD family'
NUG21_08635	COG1960	acyl-CoA dehydrogenase activity
NUG21_08655	COG0305	Participates in initiation and elongation during chromosome replication
NUG21_08665	COG0415	Belongs to the DNA photolyase family
NUG21_08675	COG3047	cAMP biosynthetic process
NUG21_08675	COG2885	chlorophyll binding
NUG21_08680	COG0583	DNA-binding transcription factor activity
NUG21_08705	COG1028	Short-chain dehydrogenase reductase Sdr
NUG21_08715	COG3706	GGDEF domain
NUG21_08740	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
NUG21_08750	COG2914	Belongs to the UPF0125 (RnfH) family
NUG21_08755	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NUG21_08760	COG0735	belongs to the Fur family
NUG21_08765	COG0497	DNA recombination
NUG21_08770	COG1420	regulation of RNA biosynthetic process
NUG21_08775	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NUG21_08780	COG0443	Heat shock 70 kDa protein
NUG21_08785	COG0484	heat shock protein binding
NUG21_08790	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
NUG21_08795	COG1605	Chorismate mutase
NUG21_08795	COG0287	Prephenate dehydrogenase
NUG21_08805	COG1132	(ABC) transporter
NUG21_08825	COG5001	Diguanylate cyclase
NUG21_08855	COG2850	peptidyl-arginine hydroxylation
NUG21_08870	COG1253	flavin adenine dinucleotide binding
NUG21_08905	COG1131	(ABC) transporter
NUG21_08910	COG1725	Transcriptional regulator
NUG21_08920	COG0386	Belongs to the glutathione peroxidase family
NUG21_08935	COG2900	Belongs to the SlyX family
NUG21_08955	COG1410	methionine synthase
NUG21_08955	COG0646	methionine synthase
NUG21_08965	COG2226	methyltransferase
NUG21_08970	COG1960	acyl-CoA dehydrogenase activity
NUG21_08975	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NUG21_08980	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NUG21_08990	COG2902	Dehydrogenase
NUG21_08995	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NUG21_09025	COG2925	Exonuclease
NUG21_09035	COG3844	kynureninase activity
NUG21_09040	COG1289	transmembrane transporter activity
NUG21_09050	COG0288	reversible hydration of carbon dioxide
NUG21_09095	COG2197	response regulator
NUG21_09120	COG0316	Belongs to the HesB IscA family
NUG21_09130	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NUG21_09135	COG0359	binds to the 23S rRNA
NUG21_09145	COG3115	cell septum assembly
NUG21_09150	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NUG21_09165	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
NUG21_09175	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
NUG21_09185	COG4993	Dehydrogenase
NUG21_09220	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
NUG21_09250	COG4221	oxidoreductase activity
NUG21_09285	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
NUG21_09290	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
NUG21_09295	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NUG21_09300	COG0077	Prephenate dehydratase
NUG21_09300	COG1605	Chorismate mutase
NUG21_09330	COG0583	DNA-binding transcription factor activity
NUG21_09400	COG1530	ribonuclease E activity
NUG21_09410	COG3064	Membrane
NUG21_09415	COG0428	transporter
NUG21_09430	COG0316	Belongs to the HesB IscA family
NUG21_09430	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
NUG21_09450	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NUG21_09470	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NUG21_09475	COG2957	Belongs to the agmatine deiminase family
NUG21_09485	COG0257	Belongs to the bacterial ribosomal protein bL36 family
NUG21_09490	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
NUG21_09500	COG0776	regulation of translation
NUG21_09510	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
NUG21_09515	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NUG21_09525	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NUG21_09530	COG0183	Belongs to the thiolase family
NUG21_09535	COG1250	3-hydroxyacyl-CoA dehydrogenase
NUG21_09535	COG1024	Enoyl-CoA hydratase
NUG21_09550	COG0820	rRNA (adenine-C2-)-methyltransferase activity
NUG21_09565	COG2976	Protein conserved in bacteria
NUG21_09570	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NUG21_09575	COG1160	GTP binding
NUG21_09580	COG0746	molybdenum cofactor guanylyltransferase activity
NUG21_09590	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NUG21_09595	COG0475	glutathione-regulated potassium exporter activity
NUG21_09595	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NUG21_09600	COG1073	alpha beta
NUG21_09610	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NUG21_09620	COG0519	Catalyzes the synthesis of GMP from XMP
NUG21_09620	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NUG21_09625	COG3002	Belongs to the UPF0753 family
NUG21_09630	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NUG21_09635	COG0583	DNA-binding transcription factor activity
NUG21_09650	COG0456	acetyltransferase
NUG21_09655	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NUG21_09675	COG0604	alcohol dehydrogenase
NUG21_09680	COG0583	DNA-binding transcription factor activity
NUG21_09695	COG5002	protein histidine kinase activity
NUG21_09725	COG1914	H( )-stimulated, divalent metal cation uptake system
NUG21_09730	COG1321	iron dependent repressor
NUG21_09740	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
NUG21_09745	COG0668	transmembrane transport
NUG21_09770	COG1028	Short-chain dehydrogenase reductase Sdr
NUG21_09775	COG1183	phosphatidylcholine synthase activity
NUG21_09785	COG3243	poly(R)-hydroxyalkanoic acid synthase
NUG21_09790	COG1983	PspC domain protein
NUG21_09800	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NUG21_09800	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
NUG21_09810	COG0784	Response regulator, receiver
NUG21_09810	COG4191	Histidine kinase
NUG21_09815	COG2183	response to ionizing radiation
NUG21_09820	COG2205	protein histidine kinase activity
NUG21_09820	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NUG21_09865	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NUG21_09885	COG2205	protein histidine kinase activity
NUG21_10060	COG1104	cysteine desulfurase activity
NUG21_10095	COG0583	DNA-binding transcription factor activity
NUG21_10150	COG1132	(ABC) transporter
NUG21_10170	COG0438	transferase activity, transferring glycosyl groups
NUG21_10215	COG2244	polysaccharide biosynthetic process
NUG21_10255	COG3474	cytochrome
NUG21_10265	COG1595	DNA-templated transcription, initiation
NUG21_10280	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NUG21_10300	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NUG21_10335	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
NUG21_10340	COG1230	cation diffusion facilitator family transporter
NUG21_10355	COG1674	ftsk spoiiie
NUG21_10360	COG0492	ferredoxin-NADP+ reductase activity
NUG21_10370	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
NUG21_10380	COG0542	response to heat
NUG21_10400	COG0482	sulfurtransferase activity
NUG21_10405	COG2915	High frequency lysogenization protein hflD homolog
NUG21_10420	COG1116	anion transmembrane transporter activity
NUG21_10465	COG0784	Response regulator, receiver
NUG21_10465	COG0835	chemotaxis
NUG21_10485	COG1749	Flagellar hook protein flgE
NUG21_10490	COG4787	bacterial-type flagellum-dependent cell motility
NUG21_10500	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
NUG21_10505	COG1706	bacterial-type flagellum-dependent cell motility
NUG21_10525	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NUG21_10530	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NUG21_10555	COG2197	response regulator
NUG21_10565	COG2201	protein-glutamate methylesterase activity
NUG21_10585	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NUG21_10590	COG1028	Short-chain dehydrogenase reductase Sdr
NUG21_10595	COG1028	Short-chain dehydrogenase reductase Sdr
NUG21_10640	COG1677	Flagellar hook-basal body complex protein FliE
NUG21_10650	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NUG21_10690	COG3190	flagellar
NUG21_10745	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
NUG21_10750	COG2198	Histidine kinase
NUG21_10750	COG0643	Histidine kinase
NUG21_10750	COG0784	Response regulator, receiver
NUG21_10755	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
NUG21_10765	COG1192	Involved in chromosome partitioning
NUG21_10770	COG0835	chemotaxis
NUG21_10780	COG0745	RESPONSE REGULATOR receiver
NUG21_10790	COG0840	transmembrane signaling receptor activity
NUG21_10800	COG0840	transmembrane signaling receptor activity
NUG21_10810	COG0840	transmembrane signaling receptor activity
NUG21_10825	COG0840	transmembrane signaling receptor activity
NUG21_10835	COG0840	transmembrane signaling receptor activity
NUG21_10845	COG0835	chemotaxis
NUG21_10855	COG0840	transmembrane signaling receptor activity
NUG21_10865	COG0840	transmembrane signaling receptor activity
NUG21_10880	COG2201	protein-glutamate methylesterase activity
NUG21_10910	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NUG21_10925	COG2828	Protein conserved in bacteria
NUG21_10930	COG0583	DNA-binding transcription factor activity
NUG21_10940	COG0318	PFAM AMP-dependent synthetase and ligase
NUG21_10945	COG1024	Enoyl-CoA hydratase
NUG21_10950	COG0784	Response regulator, receiver
NUG21_10950	COG2198	Histidine kinase
NUG21_10950	COG2205	protein histidine kinase activity
NUG21_10960	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
NUG21_10975	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
NUG21_10985	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NUG21_10990	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
NUG21_11000	COG0505	Belongs to the CarA family
NUG21_11010	COG2258	MOSC domain
NUG21_11015	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NUG21_11035	COG1024	Enoyl-CoA hydratase
NUG21_11055	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NUG21_11075	COG0277	FAD linked oxidase domain protein
NUG21_11080	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NUG21_11090	COG0531	amino acid
NUG21_11095	COG0531	amino acid
NUG21_11100	COG0235	Class ii aldolase
NUG21_11105	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
NUG21_11110	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
NUG21_11140	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NUG21_11155	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NUG21_11160	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
NUG21_11175	COG0124	histidyl-tRNA synthetase
NUG21_11180	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NUG21_11190	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NUG21_11215	COG1012	belongs to the aldehyde dehydrogenase family
NUG21_11230	COG0167	dihydroorotate dehydrogenase activity
NUG21_11235	COG0812	UDP-N-acetylmuramate dehydrogenase activity
NUG21_11245	COG1794	racemase activity, acting on amino acids and derivatives
NUG21_11265	COG0671	phosphoesterase, PA-phosphatase related
NUG21_11270	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
NUG21_11280	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
NUG21_11310	COG0166	Belongs to the GPI family
NUG21_11325	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
NUG21_11330	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NUG21_11335	COG0617	tRNA 3'-terminal CCA addition
NUG21_11345	COG1469	GTP cyclohydrolase I activity
NUG21_11350	COG0477	Major facilitator Superfamily
NUG21_11355	COG2115	Belongs to the xylose isomerase family
NUG21_11360	COG1070	Carbohydrate kinase
NUG21_11365	COG1501	Belongs to the glycosyl hydrolase 31 family
NUG21_11390	COG0800	Aldolase
NUG21_11395	COG4948	Mandelate Racemase Muconate Lactonizing
NUG21_11405	COG3734	2-keto-3-deoxy-galactonokinase
NUG21_11410	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
NUG21_11420	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NUG21_11430	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NUG21_11435	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
NUG21_11450	COG0351	phosphomethylpyrimidine kinase
NUG21_11450	COG0352	thiamine-phosphate diphosphorylase activity
NUG21_11470	COG1028	Short-chain dehydrogenase reductase Sdr
NUG21_11480	COG0583	DNA-binding transcription factor activity
NUG21_11485	COG1741	Belongs to the pirin family
NUG21_11520	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
NUG21_11525	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NUG21_11530	COG2137	regulation of response to DNA damage stimulus
NUG21_11535	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NUG21_11540	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NUG21_11545	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
NUG21_11550	COG1546	Belongs to the CinA family
NUG21_11555	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NUG21_11570	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NUG21_11575	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NUG21_11580	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
NUG21_11585	COG1534	Rna-binding protein
NUG21_11600	COG1238	metal cluster binding
NUG21_11610	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
NUG21_11625	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
NUG21_11635	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
NUG21_11645	COG0148	phosphopyruvate hydratase activity
NUG21_11655	COG2877	3-deoxy-8-phosphooctulonate synthase activity
NUG21_11665	COG0504	CTP synthase activity
NUG21_11680	COG2134	cdp-diacylglycerol pyrophosphatase
NUG21_11700	COG1253	flavin adenine dinucleotide binding
NUG21_11715	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NUG21_11725	COG1054	Belongs to the UPF0176 family
NUG21_11745	COG5002	protein histidine kinase activity
NUG21_11745	COG5001	Diguanylate cyclase
NUG21_11745	COG3447	MASE1 domain protein
NUG21_11755	COG0069	glutamate synthase activity
NUG21_11760	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
NUG21_11775	COG1609	Transcriptional regulator
NUG21_11780	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
NUG21_11780	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NUG21_11785	COG1105	Belongs to the carbohydrate kinase PfkB family
NUG21_11790	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NUG21_11790	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NUG21_11820	COG1136	(ABC) transporter
NUG21_11820	COG0577	efflux transmembrane transporter activity
NUG21_11860	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NUG21_11870	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NUG21_11875	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
NUG21_11880	COG0583	DNA-binding transcription factor activity
NUG21_11885	COG0702	epimerase
NUG21_11890	COG1309	transcriptional regulator
NUG21_11940	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NUG21_11955	COG0348	domain, Protein
NUG21_12020	COG4774	siderophore transport
NUG21_12035	COG1914	H( )-stimulated, divalent metal cation uptake system
NUG21_12050	COG0500	methyltransferase
NUG21_12080	COG0673	inositol 2-dehydrogenase activity
NUG21_12085	COG1063	alcohol dehydrogenase
NUG21_12090	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NUG21_12100	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NUG21_12125	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NUG21_12140	COG1663	tetraacyldisaccharide 4'-kinase activity
NUG21_12155	COG0811	peptide transport
NUG21_12175	COG4591	ABC-type transport system involved in lipoprotein release permease component
NUG21_12200	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
NUG21_12215	COG0354	folic acid binding
NUG21_12220	COG3842	ATPase activity
NUG21_12225	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NUG21_12240	COG0129	dihydroxy-acid dehydratase activity
NUG21_12245	COG0800	Aldolase
NUG21_12255	COG0395	ABC-type sugar transport system, permease component
NUG21_12265	COG2182	Extracellular solute-binding protein
NUG21_12290	COG2350	Protein conserved in bacteria
NUG21_12295	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NUG21_12300	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NUG21_12305	COG1187	pseudouridine synthase activity
NUG21_12335	COG0436	Aminotransferase
NUG21_12340	COG4133	protoheme IX ABC transporter activity
NUG21_12385	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NUG21_12395	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
NUG21_12400	COG4988	ABC transporter
NUG21_12410	COG1294	oxidase, subunit
NUG21_12475	COG0165	Argininosuccinate lyase
NUG21_12480	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NUG21_12490	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
NUG21_12495	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NUG21_12505	COG0137	argininosuccinate synthase activity
NUG21_12510	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NUG21_12525	COG2166	iron-sulfur cluster assembly
NUG21_12560	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
NUG21_12575	COG3706	GGDEF domain
NUG21_12580	COG4677	pectinesterase activity
NUG21_12600	COG0402	S-adenosylhomocysteine deaminase activity
NUG21_12605	COG3548	integral membrane protein
NUG21_12615	COG1509	lysine 2,3-aminomutase activity
NUG21_12655	COG1629	transport
NUG21_12655	COG4774	siderophore transport
NUG21_12670	COG0840	transmembrane signaling receptor activity
NUG21_12675	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NUG21_12680	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NUG21_12685	COG1862	Preprotein translocase
NUG21_12695	COG1132	(ABC) transporter
NUG21_12725	COG1187	pseudouridine synthase activity
NUG21_12775	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NUG21_12815	COG2080	2 iron, 2 sulfur cluster binding
NUG21_12820	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
NUG21_12825	COG1529	Aldehyde oxidase and xanthine dehydrogenase
NUG21_12830	COG0746	molybdenum cofactor guanylyltransferase activity
NUG21_12835	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
NUG21_12840	COG3214	Protein conserved in bacteria
NUG21_12865	COG0430	RNA-3'-phosphate cyclase activity
NUG21_12870	COG1690	Belongs to the RtcB family
NUG21_12885	COG4650	regulator
NUG21_12890	COG0735	belongs to the Fur family
NUG21_12915	COG4452	Inner membrane protein CreD
NUG21_12920	COG2205	protein histidine kinase activity
NUG21_12925	COG0745	RESPONSE REGULATOR receiver
NUG21_12935	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
NUG21_12940	COG3878	Protein conserved in bacteria
NUG21_12950	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NUG21_12960	COG2198	Histidine kinase
NUG21_12960	COG0643	Histidine kinase
NUG21_12975	COG0840	transmembrane signaling receptor activity
NUG21_13005	COG2211	Major facilitator Superfamily
NUG21_13020	COG0588	phosphoglycerate mutase activity
NUG21_13025	COG1515	deoxyribonuclease V activity
NUG21_13035	COG1741	Belongs to the pirin family
NUG21_13050	COG1966	Carbon starvation protein
NUG21_13055	COG2879	small protein
NUG21_13060	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NUG21_13090	COG0823	Involved in the tonB-independent uptake of proteins
NUG21_13090	COG1506	peptidase
NUG21_13095	COG1297	OPT oligopeptide transporter protein
NUG21_13100	COG3104	oligopeptide transport
NUG21_13120	COG1609	Transcriptional regulator
NUG21_13130	COG2211	Major facilitator Superfamily
NUG21_13135	COG0673	inositol 2-dehydrogenase activity
NUG21_13170	COG0629	single-stranded DNA binding
NUG21_13175	COG0142	geranyltranstransferase activity
NUG21_13200	COG0527	aspartate kinase activity
NUG21_13210	COG0384	phenazine biosynthesis protein PhzF
NUG21_13220	COG1764	response to oxidative stress
NUG21_13235	COG0739	heme binding
NUG21_13250	COG0693	protein deglycase activity
NUG21_13265	COG0719	Fe-S assembly protein
NUG21_13270	COG0396	ATPase activity
NUG21_13275	COG0719	Fe-S assembly protein
NUG21_13280	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NUG21_13290	COG2146	nitrite reductase [NAD(P)H] activity
NUG21_13295	COG0840	transmembrane signaling receptor activity
NUG21_13300	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NUG21_13305	COG3291	Pkd domain containing protein
NUG21_13310	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NUG21_13315	COG0405	Gamma-glutamyltransferase
NUG21_13320	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
NUG21_13335	COG0742	ribosomal rna small subunit methyltransferase
NUG21_13340	COG0326	Molecular chaperone. Has ATPase activity
NUG21_13365	COG3507	Belongs to the glycosyl hydrolase 43 family
NUG21_13395	COG0531	amino acid
NUG21_13410	COG0006	proline dipeptidase activity
NUG21_13420	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NUG21_13435	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NUG21_13440	COG3938	Belongs to the proline racemase family
NUG21_13450	COG0552	protein localization to endoplasmic reticulum
NUG21_13500	COG0835	chemotaxis
NUG21_13505	COG3290	protein histidine kinase activity
NUG21_13505	COG0840	transmembrane signaling receptor activity
NUG21_13510	COG0840	transmembrane signaling receptor activity
NUG21_13515	COG1201	RNA secondary structure unwinding
NUG21_13525	COG3300	MHYT domain
NUG21_13525	COG5001	Diguanylate cyclase
NUG21_13530	COG1185	polyribonucleotide nucleotidyltransferase activity
NUG21_13555	COG0195	Participates in both transcription termination and antitermination
NUG21_13570	COG1007	ATP synthesis coupled electron transport
NUG21_13605	COG1034	ATP synthesis coupled electron transport
NUG21_13610	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
NUG21_13615	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
NUG21_13625	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NUG21_13635	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NUG21_13655	COG1028	Short-chain dehydrogenase reductase Sdr
NUG21_13695	COG0159	tryptophan synthase activity
NUG21_13710	COG0135	phosphoribosylanthranilate isomerase activity
NUG21_13725	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NUG21_13735	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NUG21_13740	COG2890	protein-(glutamine-N5) methyltransferase activity
NUG21_13755	COG0741	lytic transglycosylase activity
NUG21_13760	COG0433	COG0433 Predicted ATPase
NUG21_13770	COG0494	nUDIX hydrolase
NUG21_13785	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NUG21_13815	COG1714	RDD family
NUG21_13820	COG0717	Belongs to the dCTP deaminase family
NUG21_13825	COG0489	protein tyrosine kinase activity
NUG21_13830	COG4771	TonB-dependent receptor
NUG21_13840	COG0457	Tetratricopeptide repeat
NUG21_13845	COG4206	TonB-dependent receptor
NUG21_13860	COG3590	peptidase
NUG21_13890	COG2311	Membrane
NUG21_13900	COG0791	NLP P60 protein
NUG21_13905	COG0791	NLP P60 protein
NUG21_13915	COG1607	acyl-coa hydrolase
NUG21_13920	COG2226	methyltransferase
NUG21_13925	COG1301	dicarboxylic acid transport
NUG21_13930	COG1785	Belongs to the alkaline phosphatase family
NUG21_13940	COG0037	tRNA processing
NUG21_13945	COG1722	exodeoxyribonuclease VII activity
NUG21_13950	COG0142	geranyltranstransferase activity
NUG21_13955	COG4104	PAAR repeat-containing protein
NUG21_13970	COG0312	modulator of DNA gyrase
NUG21_13980	COG0312	modulator of DNA gyrase
NUG21_14000	COG2968	Membrane
NUG21_14015	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NUG21_14030	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NUG21_14045	COG0495	leucyl-tRNA aminoacylation
NUG21_14055	COG3118	belongs to the thioredoxin family
NUG21_14065	COG5001	Diguanylate cyclase
NUG21_14065	COG4251	negative regulation of phosphorylation
NUG21_14065	COG3706	GGDEF domain
NUG21_14065	COG2203	Gaf domain
NUG21_14080	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
NUG21_14090	COG2040	homocysteine
NUG21_14095	COG0346	lactoylglutathione lyase activity
NUG21_14105	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NUG21_14105	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NUG21_14120	COG2878	Part of a membrane complex involved in electron transport
NUG21_14135	COG1595	DNA-templated transcription, initiation
NUG21_14160	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
NUG21_14175	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
NUG21_14180	COG0251	oxidation-reduction process
NUG21_14190	COG0392	lysyltransferase activity
NUG21_14225	COG2814	Major facilitator Superfamily
NUG21_14230	COG1902	pentaerythritol trinitrate reductase activity
NUG21_14235	COG2824	Alkylphosphonate utilization operon protein PhnA
NUG21_14245	COG1047	Peptidyl-prolyl cis-trans
NUG21_14250	COG1077	Cell shape determining protein MreB Mrl
NUG21_14280	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
NUG21_14290	COG1451	nucleotide metabolic process
NUG21_14295	COG1187	pseudouridine synthase activity
NUG21_14305	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NUG21_14320	COG5487	UPF0391 membrane protein
NUG21_14355	COG1703	isobutyryl-CoA mutase activity
NUG21_14355	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
NUG21_14355	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
NUG21_14375	COG0183	Belongs to the thiolase family
NUG21_14405	COG1960	acyl-CoA dehydrogenase activity
NUG21_14410	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
NUG21_14410	COG1793	dna ligase
NUG21_14415	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
NUG21_14415	COG1793	dna ligase
NUG21_14420	COG1201	RNA secondary structure unwinding
NUG21_14430	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NUG21_14435	COG1278	Cold shock
NUG21_14440	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
NUG21_14445	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
NUG21_14450	COG1472	Belongs to the glycosyl hydrolase 3 family
NUG21_14460	COG2954	triphosphatase activity
NUG21_14475	COG1381	Involved in DNA repair and RecF pathway recombination
NUG21_14480	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NUG21_14495	COG0681	Belongs to the peptidase S26 family
NUG21_14500	COG0481	GTPase activity
NUG21_14505	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NUG21_14520	COG1024	Enoyl-CoA hydratase
NUG21_14520	COG1250	3-hydroxyacyl-CoA dehydrogenase
NUG21_14545	COG1028	Short-chain dehydrogenase reductase Sdr
NUG21_14550	COG2855	membrane
NUG21_14565	COG3867	Arabinogalactan endo-beta-1,4-galactanase
NUG21_14570	COG3250	beta-galactosidase activity
NUG21_14585	COG1028	Short-chain dehydrogenase reductase Sdr
NUG21_14590	COG1028	Short-chain dehydrogenase reductase Sdr
NUG21_14600	COG3220	belongs to the UPF0276 family
NUG21_14610	COG0688	phosphatidylethanolamine metabolic process
NUG21_14615	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NUG21_14630	COG0542	response to heat
NUG21_14640	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
NUG21_14645	COG0534	Mate efflux family protein
NUG21_14650	COG0335	large ribosomal subunit rRNA binding
NUG21_14660	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NUG21_14685	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NUG21_14690	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NUG21_14710	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NUG21_14725	COG0475	glutathione-regulated potassium exporter activity
NUG21_14745	COG0625	glutathione transferase activity
NUG21_14750	COG1172	Belongs to the binding-protein-dependent transport system permease family
NUG21_14755	COG1172	Belongs to the binding-protein-dependent transport system permease family
NUG21_14760	COG1129	ABC transporter
NUG21_14765	COG1879	ABC-type sugar transport system periplasmic component
NUG21_14785	COG1028	Short-chain dehydrogenase reductase Sdr
NUG21_14790	COG0129	dihydroxy-acid dehydratase activity
NUG21_14795	COG1595	DNA-templated transcription, initiation
NUG21_14830	COG1028	Short-chain dehydrogenase reductase Sdr
NUG21_14840	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
NUG21_14845	COG1845	cytochrome c oxidase, subunit III
NUG21_14850	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NUG21_14875	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NUG21_14890	COG0196	riboflavin kinase activity
NUG21_14895	COG0728	peptidoglycan biosynthetic process
NUG21_14905	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NUG21_14910	COG0211	Belongs to the bacterial ribosomal protein bL27 family
NUG21_14915	COG0261	This protein binds to 23S rRNA in the presence of protein L20
NUG21_14920	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NUG21_14925	COG0824	Thioesterase
NUG21_14940	COG1946	Acyl-CoA thioesterase
NUG21_14955	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
NUG21_14970	COG0840	transmembrane signaling receptor activity
NUG21_14990	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NUG21_14995	COG4638	Rieske (2fe-2S)
NUG21_15065	COG4585	Histidine kinase
NUG21_15080	COG2894	cell division
NUG21_15085	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
NUG21_15095	COG2205	protein histidine kinase activity
NUG21_15100	COG0745	RESPONSE REGULATOR receiver
NUG21_15110	COG2194	sulfuric ester hydrolase activity
NUG21_15130	COG2814	Major facilitator Superfamily
NUG21_15135	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NUG21_15135	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NUG21_15140	COG0753	catalase activity
NUG21_15145	COG1063	alcohol dehydrogenase
NUG21_15170	COG1028	Short-chain dehydrogenase reductase Sdr
NUG21_15220	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NUG21_15230	COG0330	HflC and HflK could
NUG21_15235	COG0330	HflC and HflK could
NUG21_15240	COG0604	alcohol dehydrogenase
NUG21_15260	COG0678	peroxiredoxin activity
NUG21_15270	COG4953	penicillin-binding protein 1C
NUG21_15290	COG1349	DNA-binding transcription factor activity
NUG21_15300	COG2223	nitrite transmembrane transporter activity
NUG21_15305	COG2373	Large extracellular alpha-helical protein
NUG21_15355	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NUG21_15370	COG0587	DNA-directed DNA polymerase activity
NUG21_15380	COG0640	Transcriptional regulator
NUG21_15390	COG2161	toxin-antitoxin pair type II binding
NUG21_15395	COG4115	mRNA cleavage
NUG21_15415	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NUG21_15420	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NUG21_15425	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NUG21_15445	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
NUG21_15455	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NUG21_15460	COG0333	Belongs to the bacterial ribosomal protein bL32 family
NUG21_15465	COG1399	metal-binding, possibly nucleic acid-binding protein
NUG21_15490	COG0714	Associated with various cellular activities
NUG21_15510	COG0537	adenosine 5'-monophosphoramidase activity
NUG21_15515	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NUG21_15540	COG0314	molybdopterin synthase activity
NUG21_15545	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
NUG21_15550	COG0315	cyclic pyranopterin monophosphate synthase activity
NUG21_15570	COG3642	lipopolysaccharide core region biosynthetic process
NUG21_15575	COG0859	PFAM glycosyl transferase family 9
NUG21_15595	COG0631	protein serine/threonine phosphatase activity
NUG21_15605	COG0328	RNA-DNA hybrid ribonuclease activity
NUG21_15615	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NUG21_15625	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NUG21_15665	COG0544	peptidyl-prolyl cis-trans isomerase activity
NUG21_15720	COG0473	3-isopropylmalate dehydrogenase activity
NUG21_15735	COG4783	chaperone-mediated protein folding
NUG21_15740	COG0745	RESPONSE REGULATOR receiver
NUG21_15750	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
NUG21_15755	COG0248	Ppx GppA phosphatase
NUG21_15760	COG0438	transferase activity, transferring glycosyl groups
NUG21_15770	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NUG21_15780	COG3291	Pkd domain containing protein
NUG21_15785	COG2833	Protein of unknown function (DUF455)
NUG21_15805	COG0285	dihydrofolate synthase activity
NUG21_15810	COG0588	phosphoglycerate mutase activity
NUG21_15830	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
NUG21_15835	COG4208	sulfate ABC transporter
NUG21_15840	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
NUG21_15850	COG0156	8-amino-7-oxononanoate synthase activity
NUG21_15860	COG1187	pseudouridine synthase activity
NUG21_15875	COG0583	DNA-binding transcription factor activity
NUG21_15880	COG2814	Major facilitator Superfamily
NUG21_15890	COG0667	Aldo Keto reductase
NUG21_15895	COG0604	alcohol dehydrogenase
NUG21_15900	COG0446	pyridine nucleotide-disulphide oxidoreductase
NUG21_15900	COG1902	pentaerythritol trinitrate reductase activity
NUG21_15940	COG0625	glutathione transferase activity
NUG21_15945	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NUG21_15965	COG0625	glutathione transferase activity
NUG21_15985	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NUG21_15990	COG1217	gtp-binding protein TYPA
NUG21_16010	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
NUG21_16030	COG0203	ribosomal protein L17
NUG21_16040	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NUG21_16050	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NUG21_16055	COG0201	protein transport
NUG21_16065	COG1841	ribosomal large subunit assembly
NUG21_16075	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NUG21_16090	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NUG21_16095	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NUG21_16100	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NUG21_16110	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NUG21_16115	COG0255	Belongs to the universal ribosomal protein uL29 family
NUG21_16125	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NUG21_16135	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NUG21_16140	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NUG21_16145	COG0089	rRNA binding
NUG21_16150	COG0088	Forms part of the polypeptide exit tunnel
NUG21_16160	COG0051	transcription antitermination factor activity, RNA binding
NUG21_16165	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NUG21_16170	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NUG21_16175	COG0049	tRNA binding
NUG21_16185	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NUG21_16190	COG0085	RNA polymerase activity
NUG21_16195	COG0222	ribosome binding
NUG21_16200	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NUG21_16215	COG0250	Participates in transcription elongation, termination and antitermination
NUG21_16220	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
NUG21_16230	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NUG21_16250	COG0012	GTP binding
NUG21_16255	COG0193	aminoacyl-tRNA hydrolase activity
NUG21_16265	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NUG21_16275	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NUG21_16290	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
NUG21_16295	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NUG21_16315	COG0521	Mo-molybdopterin cofactor biosynthetic process
NUG21_16330	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NUG21_16335	COG1295	ribonuclease BN
NUG21_16355	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NUG21_16360	COG1404	Belongs to the peptidase S8 family
NUG21_16365	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NUG21_16425	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NUG21_16425	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NUG21_16445	COG0583	DNA-binding transcription factor activity
NUG21_16475	COG2890	protein-(glutamine-N5) methyltransferase activity
NUG21_16485	COG3634	alkyl hydroperoxide reductase activity
NUG21_16490	COG0583	DNA-binding transcription factor activity
NUG21_16495	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NUG21_16500	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NUG21_16525	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NUG21_16535	COG2197	response regulator
NUG21_16540	COG0784	Response regulator, receiver
NUG21_16540	COG2205	protein histidine kinase activity
NUG21_16540	COG5002	protein histidine kinase activity
NUG21_16555	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NUG21_16565	COG0697	spore germination
NUG21_16620	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NUG21_16625	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NUG21_16635	COG2096	Adenosyltransferase
NUG21_16650	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NUG21_16655	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
NUG21_16665	COG2967	ApaG domain
NUG21_16670	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
NUG21_16700	COG1704	LemA family
NUG21_16705	COG0861	Integral membrane protein TerC family
NUG21_16710	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
NUG21_16720	COG0745	RESPONSE REGULATOR receiver
NUG21_16725	COG2205	protein histidine kinase activity
NUG21_16740	COG0642	Histidine kinase
NUG21_16755	COG4181	ATPase activity
NUG21_16760	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
NUG21_16765	COG2175	clavaminate synthase activity
NUG21_16775	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
NUG21_16780	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NUG21_16795	COG4771	TonB-dependent receptor
NUG21_16805	COG0667	Aldo Keto reductase
NUG21_16810	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NUG21_16825	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NUG21_16830	COG4106	trans-aconitate 2-methyltransferase activity
NUG21_16885	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NUG21_16920	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
NUG21_16970	COG0840	transmembrane signaling receptor activity
NUG21_16990	COG0366	Alpha amylase catalytic
NUG21_16995	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
NUG21_17005	COG0494	nUDIX hydrolase
NUG21_17025	COG0739	heme binding
NUG21_17040	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NUG21_17050	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
NUG21_17055	COG1181	Belongs to the D-alanine--D-alanine ligase family
NUG21_17060	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
NUG21_17080	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
NUG21_17095	COG3116	cell division
NUG21_17100	COG0275	rRNA processing
NUG21_17135	COG1988	membrane-bound metal-dependent
NUG21_17140	COG0277	FAD linked oxidase domain protein
NUG21_17150	COG0745	RESPONSE REGULATOR receiver
NUG21_17155	COG2205	protein histidine kinase activity
NUG21_17165	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
NUG21_17170	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
NUG21_17195	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NUG21_17200	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
NUG21_17220	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NUG21_17220	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NUG21_17230	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NUG21_17250	COG0477	Major facilitator Superfamily
NUG21_17255	COG0488	(ABC) transporter
NUG21_17260	COG0242	peptide deformylase activity
NUG21_17265	COG0457	Tetratricopeptide repeat
NUG21_17270	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
NUG21_17275	COG1215	transferase activity, transferring glycosyl groups
NUG21_17280	COG1215	transferase activity, transferring glycosyl groups
NUG21_17295	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NUG21_17340	COG2188	Transcriptional regulator
NUG21_17350	COG1450	Type ii and iii secretion system protein
NUG21_17365	COG3166	PFAM Fimbrial assembly family protein
NUG21_17370	COG3156	type II secretion system protein K
NUG21_17375	COG4795	General secretion pathway protein
NUG21_17380	COG2165	general secretion pathway protein
NUG21_17385	COG4970	Tfp pilus assembly protein FimT
NUG21_17390	COG2165	general secretion pathway protein
NUG21_17395	COG1459	type II secretion system
NUG21_17400	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NUG21_17405	COG1404	Belongs to the peptidase S8 family
NUG21_17410	COG5295	Hep Hag repeat protein
NUG21_17430	COG0840	transmembrane signaling receptor activity
NUG21_17435	COG0047	phosphoribosylformylglycinamidine synthase activity
NUG21_17435	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NUG21_17440	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NUG21_17445	COG4974	Belongs to the 'phage' integrase family
NUG21_17465	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NUG21_17495	COG1183	phosphatidylcholine synthase activity
NUG21_17505	COG0442	prolyl-tRNA aminoacylation
NUG21_17520	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
NUG21_17525	COG1127	ABC transporter
NUG21_17530	COG3218	ABC-type transport auxiliary lipoprotein component
NUG21_17530	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
NUG21_17570	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NUG21_17575	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
NUG21_17575	COG0662	Cupin 2, conserved barrel domain protein
NUG21_17600	COG2086	electron transfer activity
NUG21_17615	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
NUG21_17615	COG0546	phosphoglycolate phosphatase activity
NUG21_17620	COG0277	FAD linked oxidase domain protein
NUG21_17625	COG0300	oxidoreductase activity
NUG21_17635	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NUG21_17670	COG0626	cystathionine gamma-synthase activity
NUG21_17700	COG0625	glutathione transferase activity
NUG21_17710	COG0513	Belongs to the DEAD box helicase family
NUG21_17715	COG0720	synthase
NUG21_17725	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
NUG21_17730	COG1956	GAF domain-containing protein
NUG21_17740	COG4206	TonB-dependent receptor
NUG21_17750	COG0583	DNA-binding transcription factor activity
NUG21_17765	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NUG21_17770	COG0546	phosphoglycolate phosphatase activity
NUG21_17775	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NUG21_17780	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NUG21_17795	COG0339	signal peptide processing
NUG21_17800	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NUG21_17810	COG2217	Heavy metal translocating P-type atpase
NUG21_17825	COG2132	Multicopper oxidase
NUG21_17850	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
NUG21_17860	COG1136	(ABC) transporter
NUG21_17865	COG0577	efflux transmembrane transporter activity
NUG21_17875	COG0577	efflux transmembrane transporter activity
NUG21_17875	COG1136	(ABC) transporter
NUG21_17880	COG0577	efflux transmembrane transporter activity
NUG21_17885	COG0577	efflux transmembrane transporter activity
NUG21_17890	COG1136	(ABC) transporter
NUG21_17890	COG0577	efflux transmembrane transporter activity
NUG21_17900	COG0577	efflux transmembrane transporter activity
NUG21_17905	COG0577	efflux transmembrane transporter activity
NUG21_17905	COG1136	(ABC) transporter
NUG21_17920	COG4191	Histidine kinase
NUG21_17930	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NUG21_17945	COG0355	proton-transporting ATP synthase activity, rotational mechanism
NUG21_17950	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NUG21_17960	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NUG21_17970	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NUG21_17980	COG0356	it plays a direct role in the translocation of protons across the membrane
NUG21_18000	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NUG21_18005	COG0508	dehydrogenase complex catalyzes the overall conversion of
NUG21_18045	COG0697	spore germination
NUG21_18060	COG1187	pseudouridine synthase activity
NUG21_18110	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NUG21_18170	COG0842	Transport permease protein
NUG21_18175	COG1131	(ABC) transporter
NUG21_18180	COG0697	spore germination
NUG21_18190	COG0025	NhaP-type Na H and K H
NUG21_18200	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
NUG21_18205	COG1573	uracil-dna glycosylase
NUG21_18215	COG3384	dioxygenase
NUG21_18225	COG0583	DNA-binding transcription factor activity
NUG21_18255	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
NUG21_18270	COG0667	Aldo Keto reductase
NUG21_18280	COG0667	Aldo Keto reductase
NUG21_18295	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NUG21_18300	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NUG21_18330	COG5001	Diguanylate cyclase
NUG21_18330	COG3300	MHYT domain
NUG21_18360	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
NUG21_18370	COG0531	amino acid
NUG21_18385	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
NUG21_18385	COG5297	Belongs to the glycosyl hydrolase family 6
NUG21_18390	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
NUG21_18390	COG5297	Belongs to the glycosyl hydrolase family 6
NUG21_18395	COG0612	Peptidase, M16
NUG21_18425	COG0741	lytic transglycosylase activity
NUG21_18445	COG2207	Transcriptional regulator
NUG21_18455	COG0598	Magnesium transport protein CorA
NUG21_18460	COG1113	amino acid transport
NUG21_18470	COG0697	spore germination
NUG21_18505	COG2409	Drug exporters of the RND superfamily
NUG21_18515	COG5520	Belongs to the glycosyl hydrolase 30 family
NUG21_18525	COG3550	peptidyl-serine autophosphorylation
NUG21_18540	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
NUG21_18655	COG2353	YceI-like domain
NUG21_18660	COG0778	Nitroreductase
NUG21_18680	COG0584	glycerophosphoryl diester phosphodiesterase
NUG21_18690	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
NUG21_18695	COG0477	Major facilitator Superfamily
NUG21_18710	COG2827	Endonuclease containing a URI domain
NUG21_18715	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NUG21_18725	COG0459	protein refolding
NUG21_18730	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NUG21_18735	COG2356	endonuclease I
NUG21_18740	COG1324	tolerance protein
NUG21_18745	COG4232	protein-disulfide reductase activity
NUG21_18750	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NUG21_18765	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
NUG21_18770	COG0511	ligase activity, forming carbon-carbon bonds
NUG21_18780	COG0439	Biotin carboxylase
NUG21_18795	COG2264	protein methyltransferase activity
NUG21_18810	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
NUG21_18815	COG4589	Belongs to the CDS family
NUG21_18840	COG0671	phosphoesterase, PA-phosphatase related
NUG21_18840	COG2453	phosphatase
NUG21_18845	COG2267	carboxylic ester hydrolase activity
NUG21_18850	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NUG21_18860	COG0138	bifunctional purine biosynthesis protein purh
NUG21_18870	COG0151	Belongs to the GarS family
NUG21_18880	COG1289	transmembrane transporter activity
NUG21_18885	COG2814	Major facilitator Superfamily
NUG21_18935	COG2816	NAD+ diphosphatase activity
NUG21_18940	COG0316	Belongs to the HesB IscA family
NUG21_18980	COG1051	belongs to the nudix hydrolase family
NUG21_18995	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
NUG21_19020	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
NUG21_19025	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NUG21_19030	COG0730	response to heat
NUG21_19035	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
NUG21_19035	COG4124	Belongs to the glycosyl hydrolase 26 family
NUG21_19045	COG0134	indole-3-glycerol-phosphate synthase activity
NUG21_19050	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NUG21_19100	COG0251	oxidation-reduction process
NUG21_19130	COG0697	spore germination
NUG21_19150	COG2894	cell division
NUG21_19190	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NUG21_19195	COG0270	DNA (cytosine-5-)-methyltransferase activity
NUG21_19275	COG3344	reverse transcriptase
NUG21_19390	COG2801	Transposase and inactivated derivatives
NUG21_19395	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NUG21_19400	COG0587	DNA-directed DNA polymerase activity
NUG21_19415	COG0582	viral genome integration into host DNA
NUG21_19555	COG2084	Dehydrogenase
NUG21_19570	COG2003	Belongs to the UPF0758 family
NUG21_19605	COG0582	viral genome integration into host DNA
NUG21_19625	COG1597	lipid kinase activity
NUG21_19635	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
NUG21_19640	COG0484	heat shock protein binding
NUG21_19675	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NUG21_19675	COG2111	Na H antiporter
NUG21_19680	COG1006	Multisubunit Na H antiporter MnhC subunit
NUG21_19685	COG0651	ATP synthesis coupled electron transport
NUG21_19695	COG2212	antiporter activity
NUG21_19700	COG1320	monovalent cation:proton antiporter activity
NUG21_19705	COG0530	calcium, potassium:sodium antiporter activity
NUG21_19710	COG0753	catalase activity
NUG21_19720	COG4773	Receptor
NUG21_19730	COG2197	response regulator
NUG21_19735	COG4585	Histidine kinase
NUG21_19745	COG1131	(ABC) transporter
NUG21_19750	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NUG21_19755	COG1136	(ABC) transporter
NUG21_19760	COG0577	efflux transmembrane transporter activity
NUG21_19780	COG0697	spore germination
NUG21_19805	COG0180	Tryptophanyl-tRNA synthetase
NUG21_19815	COG3237	CsbD-like
NUG21_19830	COG0010	Belongs to the arginase family
NUG21_19850	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
NUG21_19895	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NUG21_19920	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NUG21_19925	COG2205	protein histidine kinase activity
NUG21_19930	COG0745	RESPONSE REGULATOR receiver
NUG21_19945	COG2084	Dehydrogenase
NUG21_19950	COG1902	pentaerythritol trinitrate reductase activity
NUG21_19975	COG1404	Belongs to the peptidase S8 family
NUG21_19985	COG2814	Major facilitator Superfamily
NUG21_19990	COG0583	DNA-binding transcription factor activity
NUG21_20005	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NUG21_20010	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NUG21_20015	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
NUG21_20020	COG1764	response to oxidative stress
NUG21_20025	COG1846	Transcriptional regulator
NUG21_20035	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
NUG21_20045	COG0697	spore germination
NUG21_20050	COG0523	cobalamin synthesis protein
NUG21_20075	COG1960	acyl-CoA dehydrogenase activity
NUG21_20080	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NUG21_20115	COG1042	CoA-binding domain protein
NUG21_20115	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NUG21_20115	COG0045	succinate-CoA ligase (ADP-forming) activity
NUG21_20125	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NUG21_20130	COG3387	PFAM Glycoside hydrolase 15-related
NUG21_20135	COG0745	RESPONSE REGULATOR receiver
NUG21_20150	COG1404	Belongs to the peptidase S8 family
NUG21_20160	COG3100	YcgL domain-containing protein
NUG21_20165	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NUG21_20175	COG0463	Glycosyl transferase, family 2
NUG21_20190	COG1028	Short-chain dehydrogenase reductase Sdr
NUG21_20215	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NUG21_20230	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NUG21_20250	COG1294	oxidase, subunit
NUG21_20255	COG1271	oxidase subunit
NUG21_20270	COG0408	coproporphyrinogen oxidase activity
NUG21_20280	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NUG21_20280	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NUG21_20290	COG0589	response to stress
NUG21_20315	COG3568	Endonuclease Exonuclease Phosphatase
NUG21_20325	COG0392	lysyltransferase activity
NUG21_20335	COG0210	DNA helicase
NUG21_20340	COG0583	DNA-binding transcription factor activity
NUG21_20345	COG0477	Major facilitator Superfamily
NUG21_20360	COG0267	Belongs to the bacterial ribosomal protein bL33 family
NUG21_20365	COG0227	Belongs to the bacterial ribosomal protein bL28 family
NUG21_20375	COG0251	oxidation-reduction process
NUG21_20415	COG0463	Glycosyl transferase, family 2
NUG21_20435	COG1192	Involved in chromosome partitioning
NUG21_20440	COG0357	Ribosomal RNA small subunit methyltransferase G
NUG21_20445	COG2091	lysine biosynthetic process via aminoadipic acid
NUG21_20470	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NUG21_20485	COG1011	Hydrolase
NUG21_20515	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NUG21_20525	COG1024	Enoyl-CoA hydratase
NUG21_20530	COG1024	Enoyl-CoA hydratase
NUG21_20535	COG1960	acyl-CoA dehydrogenase activity
NUG21_20570	COG0457	Tetratricopeptide repeat
NUG21_20575	COG2205	protein histidine kinase activity
NUG21_20575	COG2198	Histidine kinase
NUG21_20575	COG0784	Response regulator, receiver
NUG21_20580	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NUG21_20585	COG3265	gluconokinase activity
NUG21_20590	COG2155	Conserved Protein
NUG21_20595	COG2094	Belongs to the DNA glycosylase MPG family
NUG21_20625	COG2911	Protein conserved in bacteria
NUG21_20630	COG0729	surface antigen
NUG21_20635	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NUG21_20645	COG3132	Protein of unknown function, DUF480
NUG21_20660	COG3210	domain, Protein
NUG21_20660	COG3210	domain, Protein
NUG21_20660	COG3210	domain, Protein
NUG21_20670	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
NUG21_20675	COG0284	orotidine-5'-phosphate decarboxylase activity
NUG21_20690	COG1609	Transcriptional regulator
NUG21_20705	COG2937	Belongs to the GPAT DAPAT family
NUG21_20760	COG3046	protein related to deoxyribodipyrimidine photolyase
NUG21_20780	COG0037	tRNA processing
NUG21_20795	COG0840	transmembrane signaling receptor activity
NUG21_20800	COG0596	Alpha beta hydrolase
NUG21_20805	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
NUG21_20825	COG0805	protein transport
NUG21_20830	COG3591	Belongs to the peptidase S1B family
NUG21_20845	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NUG21_20845	COG0519	Catalyzes the synthesis of GMP from XMP
NUG21_20870	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NUG21_20890	COG0210	DNA helicase
NUG21_20905	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
NUG21_20910	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
NUG21_20925	COG1119	ATPase activity
NUG21_20930	COG1733	regulation of RNA biosynthetic process
NUG21_20955	COG0594	ribonuclease P activity