locus-tag	class	description
XSP_000001	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
XSP_000002	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
XSP_000004	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
XSP_000006	ENOG4108K0D	peptidase, M48
XSP_000015	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
XSP_000018	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
XSP_000021	ENOG4105C5I	Dehydrogenase
XSP_000022	ENOG4105CN1	protease
XSP_000023	ENOG41063SB	peptidase
XSP_000025	ENOG4107VAM	peptidase, m28
XSP_000030	ENOG4105DQ4	alcohol dehydrogenase
XSP_000032	ENOG4105BZ8	glutamate synthase
XSP_000033	ENOG4105CBC	glutamate synthase
XSP_000036	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
XSP_000041	ENOG4105EXG	Transcriptional regulator
XSP_000043	ENOG4105E2V	Glycosyltransferase 36
XSP_000046	ENOG4108I5C	dEAD DEAH box helicase
XSP_000047	ENOG4108UT2	hemolysin iii
XSP_000054	ENOG4105C9K	Endothelin-converting enzyme 1
XSP_000056	ENOG4105CC0	LysR family Transcriptional regulator
XSP_000071	ENOG4105KVH	Transcriptional regulator
XSP_000078	ENOG4105E09	nadh pyrophosphatase
XSP_000081	ENOG4105K63	Thioredoxin
XSP_000083	ENOG4105CSH	Transporter
XSP_000092	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
XSP_000097	ENOG4105CIR	epoxide hydrolase
XSP_000104	ENOG4105CGF	Aromatic amino acid aminotransferase
XSP_000105	ENOG4105CHB	tonB-dependent Receptor
XSP_000107	ENOG41082W1	Cupin 2, conserved barrel domain protein
XSP_000110	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
XSP_000111	ENOG4105C26	Dehydrogenase
XSP_000116	ENOG4105DQE	DNA ligase
XSP_000117	ENOG4105DMF	Dehydrogenase
XSP_000118	ENOG4105BZU	Histidine kinase
XSP_000119	ENOG4105WH1	Two component transcriptional regulator luxr family
XSP_000122	ENOG4108YAB	Invasion protein
XSP_000123	ENOG4105RKW	reductase (By
XSP_000151	ENOG4105EP6	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity)
XSP_000152	ENOG4105CG3	alpha amylase, catalytic region
XSP_000153	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
XSP_000160	ENOG4107TDE	lipolytic protein G-D-S-L family
XSP_000161	ENOG4105EBR	Carboxylesterase
XSP_000164	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
XSP_000166	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
XSP_000167	ENOG4105DSG	hydrolase family 43
XSP_000168	ENOG4105ETE	Transcriptional regulator (LacI family
XSP_000169	ENOG4105D50	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate (By similarity)
XSP_000170	ENOG4105CHR	reductase
XSP_000172	ENOG4107TDE	lipolytic protein G-D-S-L family
XSP_000176	ENOG4105MIR	Phenylalanine 4-monooxygenase
XSP_000177	ENOG4108YXU	transcriptional regulator AsnC family
XSP_000178	ENOG4105CNM	Receptor
XSP_000179	ENOG4105D78	K07001 NTE family protein
XSP_000181	ENOG4105DKW	ABC transporter
XSP_000184	ENOG4108IJ8	ABC transporter
XSP_000185	ENOG4105E90	ABC transporter
XSP_000188	ENOG41067HS	methyltransferase
XSP_000194	ENOG4105D1F	ATP-binding protein
XSP_000195	ENOG4105M4E	phosphohistidine phosphatase, SixA
XSP_000197	ENOG4107RZC	phospholipase d
XSP_000198	ENOG4105KA0	thioesterase Superfamily protein
XSP_000202	ENOG4108V1U	phospholipid-binding protein
XSP_000204	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
XSP_000205	ENOG4105C5F	glutamine synthetase
XSP_000207	ENOG4105BZU	Histidine kinase
XSP_000208	ENOG4105CUX	Signal transduction histidine kinase
XSP_000209	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
XSP_000210	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
XSP_000211	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
XSP_000212	ENOG4105I9P	Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity)
XSP_000214	ENOG4105CHU	acetyl-coa acetyltransferase
XSP_000222	ENOG4107YZP	Rhodanese domain protein
XSP_000224	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
XSP_000226	ENOG4105C7K	acetolactate synthase
XSP_000227	ENOG4108TQ9	Histidine kinase
XSP_000232	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
XSP_000235	ENOG4105E2T	synthase III
XSP_000236	ENOG4107R3N	Filamentation induced by cAMP protein fic
XSP_000237	ENOG4108J2P	Alpha beta hydrolase fold
XSP_000238	ENOG4105PI0	Ferredoxin
XSP_000239	ENOG410680H	amp-dependent synthetase and ligase
XSP_000240	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
XSP_000243	ENOG4105CPF	Cell wall formation (By similarity)
XSP_000245	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
XSP_000247	ENOG4105DR9	pseudouridine synthase
XSP_000249	ENOG4108YZN	class I peptide chain release factor
XSP_000251	ENOG4105D44	asparaginase
XSP_000252	ENOG4105DGW	oligopeptidase A
XSP_000253	ENOG4105C3F	Signal peptidase i
XSP_000258	ENOG4107QP3	malate synthase g
XSP_000260	ENOG4105BZU	Histidine kinase
XSP_000266	ENOG4107QX3	carboxylase
XSP_000267	ENOG4105C1G	acyl-Coa dehydrogenase
XSP_000278	ENOG4105CKI	cobalamin synthesis protein
XSP_000280	ENOG4108TZV	Membrane
XSP_000282	ENOG4105D6Z	AFG1 family ATPase
XSP_000284	ENOG4105K56	Transcriptional regulator
XSP_000285	ENOG4108ZHJ	Organic hydroperoxide resistance protein
XSP_000290	ENOG4105CV8	reductase
XSP_000291	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
XSP_000292	ENOG4105CPC	Aldo Keto reductase
XSP_000294	ENOG4108R99	pseudouridine synthase
XSP_000296	ENOG4105CQ7	ATP-dependent helicase
XSP_000297	ENOG4105C8Q	Methyl-accepting chemotaxis
XSP_000299	ENOG4108W15	Protein of unknown function (DUF1456)
XSP_000300	ENOG4105VT2	5-hydroxyisourate hydrolase
XSP_000301	ENOG4105E1J	oxidoreductase
XSP_000305	ENOG4105C5R	Aminotransferase
XSP_000308	ENOG4105EQ2	LysR family Transcriptional regulator
XSP_000309	ENOG4107RTG	Major Facilitator superfamily
XSP_000311	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
XSP_000317	ENOG4105ETT	transcriptional Regulator, LysR family
XSP_000318	ENOG4105F8V	Hydrolase, tatD family
XSP_000320	ENOG4106NZI	LysR family Transcriptional regulator
XSP_000321	ENOG4105D94	Major Facilitator Superfamily
XSP_000325	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
XSP_000326	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
XSP_000330	ENOG4106UW1	Major Facilitator superfamily
XSP_000332	ENOG4105DAE	Methylenetetrahydrofolate reductase
XSP_000333	ENOG4105WPN	DNA integration recombination invertion protein
XSP_000334	ENOG4105DZ2	Transcriptional regulator
XSP_000335	ENOG4108UZX	fmn reductase
XSP_000339	ENOG4105ECR	NmrA family
XSP_000342	ENOG4105C8Q	Methyl-accepting chemotaxis
XSP_000354	ENOG4105C01	Dihydroxy-acid dehydratase
XSP_000357	ENOG4108Z0R	Transferase
XSP_000358	ENOG4105D2S	major facilitator superfamily
XSP_000359	ENOG4105CPI	Metal Dependent Phosphohydrolase
XSP_000365	ENOG41072AC	4-hydroxybenzoate 3-monooxygenase
XSP_000367	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
XSP_000368	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
XSP_000369	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
XSP_000370	ENOG4105E98	transcriptional regulator DeoR family
XSP_000376	ENOG4105CHU	acetyl-coa acetyltransferase
XSP_000379	ENOG4107RAW	3-carboxy-cis-cis-muconate cycloisomerase
XSP_000380	ENOG4105F2Z	3-oxoadipate enol-lactonase
XSP_000381	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
XSP_000383	ENOG4107HP6	Transcriptional regulator
XSP_000386	ENOG4105MH3	Protein of unknown function (DUF2490)
XSP_000387	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
XSP_000395	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
XSP_000397	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
XSP_000398	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
XSP_000399	ENOG41081UC	Inherit from COG: Competence protein
XSP_000400	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
XSP_000407	ENOG4105EGS	Mechanosensitive ion channel
XSP_000410	ENOG4105CKW	Inner membrane protein yedI
XSP_000412	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
XSP_000413	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
XSP_000414	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
XSP_000419	ENOG4105K4T	epimerase
XSP_000427	ENOG4105BZS	acriflavin resistance protein
XSP_000429	ENOG4107GJV	short-chain dehydrogenase reductase
XSP_000430	ENOG4105KVH	Transcriptional regulator
XSP_000432	ENOG4105C1J	atp-dependent rna helicase
XSP_000433	ENOG4107RN0	branched-chain alpha-keto acid dehydrogenase subunit E2
XSP_000435	ENOG4105CPP	Dehydrogenase, E1 component
XSP_000436	ENOG4107RUY	(E1 component), alpha subunit
XSP_000439	ENOG4105DUX	Transporter
XSP_000442	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
XSP_000443	ENOG4105F1J	Homogentisate 1,2-dioxygenase
XSP_000445	ENOG4105KJM	monovalent cation h antiporter subunit g
XSP_000446	ENOG4105W4C	monovalent cation H antiporter subunit F
XSP_000448	ENOG4107R4Z	monovalent cation h antiporter subunit d
XSP_000449	ENOG4108ZE9	Monovalent cation H antiporter subunit C
XSP_000450	ENOG4105D65	subunit l
XSP_000457	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
XSP_000461	ENOG4107TE5	Lipid kinase
XSP_000462	ENOG4105CRQ	synthase (Component I)
XSP_000465	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
XSP_000467	ENOG4105C8Q	Methyl-accepting chemotaxis
XSP_000468	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
XSP_000469	ENOG4105CPQ	Dehydrogenase
XSP_000470	ENOG4105CEP	NADH dehydrogenase
XSP_000474	ENOG4105C8Q	Methyl-accepting chemotaxis
XSP_000476	ENOG4105R1U	AraC Family Transcriptional Regulator
XSP_000479	ENOG4105K56	Transcriptional regulator
XSP_000482	ENOG4105DDQ	anthranilate synthase
XSP_000484	ENOG4108I0Q	anthranilate phosphoribosyltransferase
XSP_000487	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
XSP_000492	ENOG4108UJD	30S ribosomal protein S9
XSP_000495	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
XSP_000497	ENOG4108UQY	Iron-storage protein
XSP_000498	ENOG4105BZU	Histidine kinase
XSP_000503	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
XSP_000506	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
XSP_000512	ENOG4105EM2	membrane
XSP_000513	ENOG4105C12	Phosphoribosylglycinamide synthetase
XSP_000514	ENOG4105DC1	bifunctional purine biosynthesis protein purh
XSP_000517	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
XSP_000521	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
XSP_000524	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
XSP_000526	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
XSP_000527	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
XSP_000528	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
XSP_000529	ENOG4105VF7	tolerance protein
XSP_000530	ENOG4108K8S	endonuclease I
XSP_000532	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
XSP_000535	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
XSP_000540	ENOG4108S3W	Anti-feci sigma factor, fecr
XSP_000546	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
XSP_000551	ENOG4108YYC	ycei family
XSP_000552	ENOG4105Q26	Siderophore-interacting protein
XSP_000555	ENOG4105WSE	Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism (By similarity)
XSP_000558	ENOG41065ZS	Transfers 2'-(5-triphosphoribosyl)-3'-dephosphocoenzyme- A to the apo- acyl-carrier-protein of the malonate decarboxylase to yield holo- acyl-carrier-protein (By similarity)
XSP_000562	ENOG4105DRR	Transcriptional regulator, GntR family
XSP_000563	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
XSP_000570	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
XSP_000571	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
XSP_000575	ENOG4105C4R	Atp-dependent dna helicase
XSP_000592	ENOG4108SF5	RNA Polymerase
XSP_000594	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
XSP_000607	ENOG4105CHF	Glutathione S-transferase
XSP_000615	ENOG4105C5Z	peptidase
XSP_000616	ENOG4107QS8	(LipO)protein
XSP_000617	ENOG4105BZU	Histidine kinase
XSP_000621	ENOG4105DFI	Membrane
XSP_000622	ENOG4105F87	Dehydratase
XSP_000634	ENOG4105BZU	Histidine kinase
XSP_000636	ENOG4105C8Q	Methyl-accepting chemotaxis
XSP_000637	ENOG4106R7G	Glycoside hydrolase family 5
XSP_000638	ENOG4105CHH	sulfate transporter
XSP_000639	ENOG4105BZU	Histidine kinase
XSP_000641	ENOG4105C3A	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity)
XSP_000643	ENOG4108HRK	Histidine kinase
XSP_000644	ENOG4108NEV	two component transcriptional regulator, LytTR family
XSP_000645	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
XSP_000653	ENOG4105WD1	Membrane
XSP_000655	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
XSP_000659	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
XSP_000660	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
XSP_000665	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
XSP_000666	ENOG4105BZU	Histidine kinase
XSP_000667	ENOG4105CD8	aminopeptidase N
XSP_000670	ENOG4105DZG	Dehydrogenase
XSP_000671	ENOG4108Q1J	Extracellular solute-binding protein, family 3
XSP_000676	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
XSP_000677	ENOG4107T4Z	adenosine kinase
XSP_000679	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
XSP_000682	ENOG4105CNI	cell division protein FtsW
XSP_000683	ENOG4107WN4	Polygalacturonase
XSP_000684	ENOG4105CVE	Lytic murein transglycosylase
XSP_000685	ENOG4105K6T	rare lipoprotein A
XSP_000686	ENOG4105DZ1	carboxypeptidase
XSP_000690	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
XSP_000691	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
XSP_000692	ENOG4105CN1	protease
XSP_000703	ENOG4108J5G	6-phosphogluconate dehydrogenase
XSP_000704	ENOG4105D9R	oxidoreductase
XSP_000705	ENOG4105W4M	Transport-associated protein
XSP_000706	ENOG4105BZU	Histidine kinase
XSP_000708	ENOG4105BZU	Histidine kinase
XSP_000710	ENOG410642E	Short chain dehydrogenase
XSP_000717	ENOG4105GVR	general secretion pathway protein D
XSP_000718	ENOG4107QHF	type ii secretion system protein e
XSP_000719	ENOG4105D7Q	type ii secretion system
XSP_000720	ENOG4108VAU	general secretion pathway protein G
XSP_000721	ENOG4105VWV	general secretion pathway protein h
XSP_000722	ENOG4105X5Z	General secretion pathway protein I
XSP_000729	ENOG4105CNT	hydrolase family 2
XSP_000734	ENOG4105ETE	Transcriptional regulator (LacI family
XSP_000735	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
XSP_000736	ENOG4105CE4	GlcNAc 6-P deacetylase
XSP_000739	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
XSP_000741	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
XSP_000743	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
XSP_000745	ENOG4105C94	Transporter
XSP_000747	ENOG4108Z33	Thiol disulfide Interchange Protein
XSP_000749	ENOG4106RE7	Cytochrome
XSP_000750	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
XSP_000751	ENOG4105CY0	Metallo-Beta-Lactamase
XSP_000754	ENOG4105JJR	Histidine kinase
XSP_000758	ENOG410903D	sensor protein
XSP_000761	ENOG4108QBQ	Catalyzes the condensation of formaldehyde and glutathione to S-hydroxymethylglutathione (By similarity)
XSP_000762	ENOG4105C4W	S-formylglutathione hydrolase
XSP_000763	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
XSP_000768	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
XSP_000769	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
XSP_000771	ENOG4105C08	Histidine kinase
XSP_000772	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
XSP_000773	ENOG4105CQB	FAD linked oxidase domain protein
XSP_000774	ENOG4105S2T	inner membrane protein YbcI
XSP_000781	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
XSP_000782	ENOG4106932	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
XSP_000783	ENOG4105CJN	penicillin-binding protein
XSP_000784	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
XSP_000785	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
XSP_000789	ENOG4105DFU	Cell wall formation (By similarity)
XSP_000790	ENOG4105CPF	Cell wall formation (By similarity)
XSP_000791	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
XSP_000792	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
XSP_000793	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
XSP_000794	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
XSP_000796	ENOG4105DR5	peptidase
XSP_000797	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
XSP_000799	ENOG4105M6F	mutator MutT protein
XSP_000802	ENOG4105SYT	Methylenetetrahydrofolate reductase
XSP_000812	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
XSP_000814	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
XSP_000818	ENOG4105D6F	Phosphatase
XSP_000822	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
XSP_000823	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
XSP_000825	ENOG4105D9N	nucleoside
XSP_000826	ENOG4105CPC	Aldo Keto reductase
XSP_000828	ENOG4105D05	Receptor
XSP_000832	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
XSP_000835	ENOG4105E2B	Taurine dioxygenase
XSP_000837	ENOG4108I0Y	(ABC) transporter
XSP_000838	ENOG4108UJV	acyl-CoA thioesterase i
XSP_000840	ENOG4105DHQ	Histidine kinase
XSP_000842	ENOG41080IJ	Diacylglycerol kinase
XSP_000849	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
XSP_000850	ENOG4105NWN	ApaG protein
XSP_000851	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
XSP_000854	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
XSP_000856	ENOG4108WBT	adenosyltransferase
XSP_000858	ENOG4105D0A	hydroxylase
XSP_000859	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
XSP_000866	ENOG4105DDW	LysR family Transcriptional regulator
XSP_000867	ENOG4105CEY	Amp-dependent synthetase and ligase
XSP_000869	ENOG4108D7R	p-hydroxycinnamoyl CoA hydratase lyase
XSP_000879	ENOG4105DXC	membrane
XSP_000880	ENOG4105CX6	glutaminyL-tRNA synthetase
XSP_000884	ENOG4105BZU	Histidine kinase
XSP_000885	ENOG4105WH1	Two component transcriptional regulator luxr family
XSP_000887	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
XSP_000889	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
XSP_000890	ENOG4105NXH	GreA GreB family elongation factor
XSP_000891	ENOG4105C5Q	Transcriptional regulator
XSP_000894	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
XSP_000898	ENOG4105C2M	dna polymerase I
XSP_000904	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
XSP_000908	ENOG4105W8H	transhydrogenase (subunit alpha
XSP_000909	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
XSP_000913	ENOG4105CM2	brancheD-chain amino acid aminotransferase
XSP_000914	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
XSP_000915	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
XSP_000916	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
XSP_000917	ENOG4108Z66	YbaK ebsC protein
XSP_000920	ENOG4105CS1	NAD(P)H quinone oxidoreductase
XSP_000921	ENOG4107S2Z	UPF0761 membrane protein
XSP_000922	ENOG4107QX9	Thiol disulfide interChange protein
XSP_000925	ENOG4105CSR	polyphosphate kinase 2
XSP_000926	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
XSP_000929	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
XSP_000930	ENOG4105DJQ	tetratricopeptide tpr_2 repeat protein
XSP_000931	ENOG4105QVB	outer membrane lipoprotein LolB
XSP_000934	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
XSP_000935	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
XSP_000936	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
XSP_000937	ENOG4105C3G	gtp-binding protein
XSP_000941	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
XSP_000943	ENOG4105PM1	preprotein translocase subunit SecE
XSP_000944	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
XSP_000945	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
XSP_000946	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
XSP_000947	ENOG4108VZM	50s ribosomal protein L10
XSP_000948	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
XSP_000950	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
XSP_000953	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
XSP_000954	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
XSP_000955	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
XSP_000959	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
XSP_000962	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
XSP_000965	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
XSP_000967	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
XSP_000975	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
XSP_000976	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
XSP_000982	ENOG41080I0	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
XSP_000983	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
XSP_000985	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
XSP_000987	ENOG4105CI3	gtp-binding protein typa
XSP_000988	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
XSP_000989	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
XSP_000990	ENOG4108K3A	Glutathione S-transferase
XSP_000993	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
XSP_000994	ENOG4105CIS	alcohol dehydrogenase
XSP_000995	ENOG4105F37	PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6
XSP_000997	ENOG4108R99	pseudouridine synthase
XSP_000999	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
XSP_001000	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
XSP_001001	ENOG4108I5D	sulfate abc transporter
XSP_001003	ENOG4108IJ6	ABC transporter
XSP_001005	ENOG4105CPQ	Dehydrogenase
XSP_001007	ENOG4105HSS	phospholipase C
XSP_001009	ENOG4105CVJ	phosphoglycerate mutase
XSP_001011	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
XSP_001014	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
XSP_001015	ENOG4105ED9	Protein of unknown function (DUF455)
XSP_001016	ENOG4108YP4	Metalloprotease, specifically cleaves on the N-terminal side of aspartyl, glutamyl and cysteic acid residues (By similarity)
XSP_001018	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
XSP_001019	ENOG4105EYK	Phosphatidylglycerophosphatase B
XSP_001020	ENOG4105BZF	Glycosyl transferase (Group 1
XSP_001021	ENOG4105C9X	ppx gppa phosphatase
XSP_001022	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
XSP_001023	ENOG4105BZU	Histidine kinase
XSP_001024	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
XSP_001025	ENOG4105ERG	peptidase m48, ste24p
XSP_001026	ENOG4105VW4	glutaredoxin 3
XSP_001028	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
XSP_001061	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
XSP_001095	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
XSP_001097	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
XSP_001103	ENOG4105EIN	peptidylprolyl cis-trans isomerase
XSP_001104	ENOG41068JE	domain protein
XSP_001105	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
XSP_001107	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
XSP_001108	ENOG4107RZZ	dna polymerase iii epsilon subunit
XSP_001109	ENOG4108ZF3	Phosphatase
XSP_001112	ENOG4105DKP	glycosyl transferase, family 9
XSP_001114	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
XSP_001115	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
XSP_001116	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
XSP_001117	ENOG4105M00	molybdopterin converting factor, subunit 1
XSP_001118	ENOG4108ZAF	Molybdopterin
XSP_001121	ENOG4107QMP	dna polymerase iii subunits gamma and tau
XSP_001122	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
XSP_001123	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
XSP_001124	ENOG4105K59	histidine triad (HIT) protein
XSP_001126	ENOG4105F8C	transglutaminase domain-containing protein
XSP_001128	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
XSP_001130	ENOG41089I4	Inherit from COG: Glycosyl transferase, family 2
XSP_001132	ENOG4108UHJ	MAF-like protein
XSP_001133	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
XSP_001134	ENOG4105VGS	50s ribosomal protein l32
XSP_001135	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
XSP_001137	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
XSP_001138	ENOG4105CHR	reductase
XSP_001140	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
XSP_001142	ENOG4105HHA	aminodeoxychorismate lyase
XSP_001143	ENOG4107QRG	dna polymerase iii
XSP_001147	ENOG4108JU7	Transcriptional regulator
XSP_001148	ENOG4105CR4	methylisocitrate lyase
XSP_001149	ENOG4105BZN	citrate synthase
XSP_001151	ENOG4108I0Z	Aconitate hydratase
XSP_001152	ENOG4105YAJ	CopG Arc MetJ
XSP_001154	ENOG4105C7F	AcnD-accessory protein PrpF
XSP_001157	ENOG4105DN3	alpha-2-macroglobulin domain protein
XSP_001163	ENOG4108JQB	penicillin-binding protein 1C
XSP_001168	ENOG4105M3Z	response regulator
XSP_001169	ENOG4107QJR	hflk protein
XSP_001170	ENOG4105EPW	hflc protein
XSP_001178	ENOG4105F6U	Short-chain dehydrogenase reductase Sdr
XSP_001179	ENOG4108XFH	Transcriptional regulator
XSP_001181	ENOG4105DZR	Type I site-specific deoxyribonuclease
XSP_001188	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
XSP_001190	ENOG4107Z4K	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
XSP_001192	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
XSP_001194	ENOG4105CWX	Alpha-1,2-mannosidase
XSP_001200	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
XSP_001201	ENOG4105H67	Protein of unknown function (DUF421)
XSP_001204	ENOG4105DPW	Major facilitator superfamily MFS_1
XSP_001205	ENOG4105EY3	heparinase II III family protein
XSP_001210	ENOG4105C7W	Xanthine dehydrogenase
XSP_001211	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
XSP_001212	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
XSP_001222	ENOG4105EPD	Oligopeptide transporter, Opt family
XSP_001225	ENOG4105TW1	Carbohydrate-selective porin OprB
XSP_001226	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
XSP_001231	ENOG4106AXJ	AraC family transcriptional regulator
XSP_001233	ENOG4105CV8	reductase
XSP_001234	ENOG4105EBR	Carboxylesterase
XSP_001235	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
XSP_001236	ENOG4105C2C	drug resistance transporter, Bcr CflA
XSP_001240	ENOG4105DIJ	Phosphoethanolamine transferase
XSP_001242	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
XSP_001243	ENOG4105ETX	regulatoR
XSP_001244	ENOG4105US7	Histidine kinase
XSP_001248	ENOG4107QMS	site-determining protein
XSP_001249	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
XSP_001251	ENOG4105BZU	Histidine kinase
XSP_001252	ENOG4105WH1	Two component transcriptional regulator luxr family
XSP_001263	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
XSP_001265	ENOG4105GFR	rna polymerase sigma factor
XSP_001267	ENOG4105C29	acyl-CoA thioesterase
XSP_001268	ENOG4105UPE	Enoyl-CoA hydratase
XSP_001270	ENOG4108TGP	Thioesterase superfamily protein
XSP_001271	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
XSP_001273	ENOG4105K46	50S ribosomal protein l27
XSP_001276	ENOG4105CJR	Integral membrane protein (MviN
XSP_001277	ENOG4105DTN	riboflavin biosynthesis protein ribF
XSP_001279	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
XSP_001280	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
XSP_001282	ENOG4105E2S	oxidase) subunit II
XSP_001283	ENOG4105BZ9	Cytochrome C oxidase, subunit I
XSP_001284	ENOG4105CCU	oxidase (Subunit III)
XSP_001285	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
XSP_001287	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
XSP_001288	ENOG4105KAF	membrAne
XSP_001291	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
XSP_001293	ENOG4107MMM	Anti-sigma-factor antagonist
XSP_001294	ENOG4105FUA	antagonist
XSP_001295	ENOG4105QD0	anti-sigma regulatory factor serine threonine protein kinase
XSP_001297	ENOG4105BZU	Histidine kinase
XSP_001301	ENOG4105KCV	RNA signal recognition particle 4.5S RNA
XSP_001302	ENOG4105C08	Histidine kinase
XSP_001303	ENOG4107Z5C	methylesterase
XSP_001304	ENOG4105BZU	Histidine kinase
XSP_001305	ENOG4105BZU	Histidine kinase
XSP_001306	ENOG4105BZU	Histidine kinase
XSP_001311	ENOG4105CZZ	Alpha-N-arabinofuranosidase (EC 3.2.1.55)
XSP_001312	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
XSP_001313	ENOG4105CRE	cytochrome C
XSP_001314	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
XSP_001315	ENOG4105EA8	2-Nitropropane dioxygenase
XSP_001318	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
XSP_001319	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
XSP_001321	ENOG4107QJQ	Mate efflux family protein
XSP_001322	ENOG4105VEJ	Heat shock protein
XSP_001323	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
XSP_001325	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
XSP_001326	ENOG4107Z3H	Transcriptional regulator, TetR family
XSP_001329	ENOG4105C8Q	Methyl-accepting chemotaxis
XSP_001332	ENOG4108NEV	two component transcriptional regulator, LytTR family
XSP_001334	ENOG4106NZI	LysR family Transcriptional regulator
XSP_001335	ENOG4105C7K	acetolactate synthase
XSP_001338	ENOG4105CNT	hydrolase family 2
XSP_001339	ENOG4106FKC	arabinogalactan endo-1,4-beta-galactosidase
XSP_001341	ENOG4105CFF	transcriptional regulator
XSP_001342	ENOG4105C26	Dehydrogenase
XSP_001343	ENOG4105C1G	acyl-Coa dehydrogenase
XSP_001345	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
XSP_001346	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
XSP_001349	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
XSP_001350	ENOG4105EMN	RNA polymerase sigma factor
XSP_001352	ENOG4105C0H	protease
XSP_001354	ENOG4105C3F	Signal peptidase i
XSP_001356	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
XSP_001358	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
XSP_001362	ENOG4107ZXU	DSBA oxidoreductase
XSP_001363	ENOG4108QDE	fad dependent oxidoreductase
XSP_001364	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
XSP_001365	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
XSP_001366	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
XSP_001367	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
XSP_001368	ENOG4105VEQ	Cold shock protein
XSP_001369	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
XSP_001371	ENOG4107QRT	dEAD DEAH box helicase
XSP_001372	ENOG4107T0X	DNA ligase
XSP_001374	ENOG4107T0X	DNA ligase
XSP_001380	ENOG4105CHU	acetyl-coa acetyltransferase
XSP_001384	ENOG4108VKG	metal-dependent hydrolase
XSP_001387	ENOG4105KSC	Transcriptional regulator, TraR DksA family
XSP_001390	ENOG4105DFF	Rod shape-determining protein mreb
XSP_001391	ENOG4108YZY	peptidylprolyl cis-trans isomerase
XSP_001393	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
XSP_001397	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
XSP_001398	ENOG4105F27	Major Facilitator
XSP_001406	ENOG4105M4H	endoribonuclease L-psp
XSP_001407	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
XSP_001410	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
XSP_001415	ENOG4105K6V	RNA polymerase
XSP_001418	ENOG4108R3D	Electron transport complex
XSP_001420	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
XSP_001423	ENOG4105DA5	(ABC) transporter
XSP_001424	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
XSP_001425	ENOG4108IQI	permease
XSP_001426	ENOG4107QK5	Homocysteine s-methyltransferase
XSP_001437	ENOG4108YXA	Membrane
XSP_001440	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
XSP_001441	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
XSP_001442	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
XSP_001444	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
XSP_001447	ENOG4105DZP	Membrane-associated zinc metalloprotease
XSP_001448	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
XSP_001449	ENOG4105KNE	Phosphatidate cytidylyltransferase
XSP_001450	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
XSP_001452	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
XSP_001454	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
XSP_001455	ENOG4105CE9	30S ribosomal protein S2
XSP_001462	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
XSP_001463	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
XSP_001466	ENOG4105KUZ	arsenate reductase
XSP_001467	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
XSP_001469	ENOG4105CAQ	asparagine synthetase
XSP_001471	ENOG4108ESX	Receptor
XSP_001473	ENOG4108UWD	Iron-storage protein
XSP_001474	ENOG4105FQ6	thiopurine methyltransferase
XSP_001475	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
XSP_001479	ENOG4105CW7	secretion protein, HlyD family
XSP_001480	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
XSP_001486	ENOG4105DUX	Transporter
XSP_001492	ENOG4105DGW	oligopeptidase A
XSP_001494	ENOG4105DP0	ferredoxin-NADP reductase
XSP_001496	ENOG4107GFK	fumarate
XSP_001499	ENOG4108V9Q	carbonic anhydrase
XSP_001500	ENOG4105HDD	phospholipase
XSP_001501	ENOG4105SXS	Protein of unknown function (DUF456)
XSP_001502	ENOG4105VEQ	Cold shock protein
XSP_001505	ENOG4105CUZ	uba thif-type nad fad binding protein
XSP_001506	ENOG4105F8V	Hydrolase, tatD family
XSP_001509	ENOG4105C1G	acyl-Coa dehydrogenase
XSP_001511	ENOG4108RXX	maleylacetoacetate isomerase
XSP_001512	ENOG4105CAQ	asparagine synthetase
XSP_001514	ENOG4105CDU	Replicative dna helicase
XSP_001515	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
XSP_001516	ENOG4105CDV	Ompa motb domain protein
XSP_001517	ENOG4105CR8	Transcriptional regulator
XSP_001520	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
XSP_001524	ENOG4105BZU	Histidine kinase
XSP_001526	ENOG4105BZU	Histidine kinase
XSP_001536	ENOG4105W5Q	DNA repair protein (RadC
XSP_001546	ENOG4105CHR	reductase
XSP_001572	ENOG4105EYM	Major Facilitator superfamily
XSP_001584	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
XSP_001585	ENOG41090R7	Ferric uptake
XSP_001586	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
XSP_001587	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
XSP_001588	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
XSP_001589	ENOG4105CFG	Acts as a chaperone (By similarity)
XSP_001590	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
XSP_001597	ENOG4105C5Q	Transcriptional regulator
XSP_001598	ENOG4105BZ1	(ABC) transporter
XSP_001600	ENOG4108URH	decarboxylase
XSP_001602	ENOG4105C7S	Dehydrogenase
XSP_001603	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
XSP_001605	ENOG4105EZE	Cupin 4 family protein
XSP_001606	ENOG4107QTF	adenylosuccinate lyase
XSP_001607	ENOG4105C37	(CBS) domain
XSP_001613	ENOG4105CZV	ABC transporter
XSP_001614	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
XSP_001617	ENOG4108V1T	peptidylprolyl cis-trans isomerase
XSP_001618	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
XSP_001622	ENOG4105ETE	Transcriptional regulator (LacI family
XSP_001624	ENOG4105D7K	pfkb domain protein
XSP_001626	ENOG4105C3R	Methionine synthase
XSP_001627	ENOG4105C3R	Methionine synthase
XSP_001628	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
XSP_001629	ENOG4105C1G	acyl-Coa dehydrogenase
XSP_001633	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
XSP_001635	ENOG4105C2N	RNA methyltransferase TrmH family group 3
XSP_001637	ENOG4105BZU	Histidine kinase
XSP_001638	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
XSP_001640	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
XSP_001641	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
XSP_001642	ENOG4105E2Z	phosphate ABC transporter (Permease
XSP_001643	ENOG4105C8U	phosphate abc transporter
XSP_001644	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
XSP_001648	ENOG4107B2H	carbonic anhydrase
XSP_001649	ENOG4105CHH	sulfate transporter
XSP_001650	ENOG4105CSM	endonuclease III
XSP_001652	ENOG4105E39	Enoyl-CoA hydratase
XSP_001653	ENOG4108V1T	peptidylprolyl cis-trans isomerase
XSP_001654	ENOG4105P8F	nudix hydrolase
XSP_001655	ENOG4105KHC	sulfurtransferase
XSP_001662	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
XSP_001663	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
XSP_001665	ENOG4105IH7	synthase
XSP_001668	ENOG4105CJB	Exodeoxyribonuclease I
XSP_001669	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
XSP_001670	ENOG4105CKY	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively (By similarity)
XSP_001672	ENOG4105C3W	Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate (By similarity)
XSP_001673	ENOG41077A9	carbonic anhydrase
XSP_001677	ENOG4105C5S	asparaginyl-tRNA synthetase
XSP_001678	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
XSP_001684	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
XSP_001686	ENOG4105CIH	Imidazole acetol-phosphate transaminase
XSP_001687	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
XSP_001688	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
XSP_001691	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
XSP_001692	ENOG4105DZG	Dehydrogenase
XSP_001695	ENOG4105CGP	Urocanate hydratase
XSP_001697	ENOG4105C84	Histidine ammonia-lyase
XSP_001705	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
XSP_001706	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
XSP_001707	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
XSP_001709	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
XSP_001712	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
XSP_001713	ENOG4105CC0	LysR family Transcriptional regulator
XSP_001718	ENOG4105DKD	Incises the DNA at the 3' side of a lesion during nucleotide excision repair. Incises the DNA farther away from the lesion than UvrC. Not able to incise the 5' site of a lesion. When a lesion remains because UvrC is not able to induce the 3' incision, Cho incises the DNA. Then UvrC makes the 5' incision. The combined action of Cho and UvrC broadens the substrate range of nucleotide excision repair (By similarity)
XSP_001720	ENOG4108SF5	RNA Polymerase
XSP_001721	ENOG4108S3W	Anti-feci sigma factor, fecr
XSP_001723	ENOG4105CA0	peroxidase
XSP_001725	ENOG4105WD1	Membrane
XSP_001726	ENOG4108YNN	Heme oxygenase
XSP_001730	ENOG4108S3W	Anti-feci sigma factor, fecr
XSP_001731	ENOG4108SF5	RNA Polymerase
XSP_001733	ENOG4105W5Q	DNA repair protein (RadC
XSP_001737	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
XSP_001752	ENOG4108N8X	transition metal ion binding
XSP_001754	ENOG4105DQE	DNA ligase
XSP_001757	ENOG4105C8Q	Methyl-accepting chemotaxis
XSP_001760	ENOG4105C8Q	Methyl-accepting chemotaxis
XSP_001766	ENOG4105C8Q	Methyl-accepting chemotaxis
XSP_001770	ENOG4105CQZ	Histidine kinase
XSP_001774	ENOG4105KWW	Biogenesis protein
XSP_001775	ENOG4107QX9	Thiol disulfide interChange protein
XSP_001776	ENOG4105DA4	cytochrome c-type biogenesis protein
XSP_001777	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
XSP_001779	ENOG41060IM	Heme exporter protein
XSP_001782	ENOG4105EMN	RNA polymerase sigma factor
XSP_001792	ENOG4105EGZ	biosynthesis protein
XSP_001796	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
XSP_001798	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
XSP_001799	ENOG4107QPH	glycogen) synthase
XSP_001800	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
XSP_001803	ENOG4105EHU	Circadian clock protein KaiC
XSP_001805	ENOG41079KZ	Major Facilitator Superfamily
XSP_001806	ENOG4105DEN	Luciferase family
XSP_001814	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
XSP_001816	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
XSP_001817	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
XSP_001818	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
XSP_001821	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
XSP_001822	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
XSP_001823	ENOG4108DG9	Smr protein MutS2
XSP_001824	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
XSP_001825	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
XSP_001826	ENOG4108UM1	dedA family
XSP_001827	ENOG4108K5P	(LipO)protein
XSP_001829	ENOG4105HBR	Rna-binding protein
XSP_001830	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
XSP_001831	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
XSP_001832	ENOG4105EEI	dihydropteroate synthase
XSP_001835	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
XSP_001836	ENOG4107TH8	cina domain protein
XSP_001838	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
XSP_001840	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
XSP_001841	ENOG4105Y3E	Modulates RecA activity (By similarity)
XSP_001842	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
XSP_001845	ENOG4107SDU	Methyl-accepting chemotaxis
XSP_001847	ENOG4105CWB	LysR family transcriptional Regulator
XSP_001852	ENOG4105DWF	phosphomethylpyrimidine kinase
XSP_001855	ENOG4108IAB	Phoh family
XSP_001856	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
XSP_001859	ENOG4107TUS	Dihydrodipicolinate synthase
XSP_001861	ENOG4108Z4U	Ferredoxin
XSP_001862	ENOG4105EI3	2-dehydro-3-deoxygalactonokinase EC 2.7.1.58
XSP_001865	ENOG4108RTU	Aldolase
XSP_001874	ENOG4105CMG	Carbohydrate kinase
XSP_001875	ENOG4105C93	Xylose Isomerase
XSP_001880	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
XSP_001881	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
XSP_001883	ENOG4105DJ0	Poly(A) Polymerase
XSP_001884	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
XSP_001885	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
XSP_001886	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
XSP_001895	ENOG4105KU2	hydrolase family 5
XSP_001896	ENOG4108UYB	regulatoR
XSP_001898	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
XSP_001899	ENOG410841Q	phosphoesterase PA-phosphatase related protein
XSP_001902	ENOG4108SXK	Transporter Drug Metabolite Exporter family
XSP_001903	ENOG4105D4A	Cell wall formation (By similarity)
XSP_001907	ENOG4105C26	Dehydrogenase
XSP_001913	ENOG4105CND	Glycosyl transferase, family 2
XSP_001914	ENOG4107BJW	polysaccharide deacetylase
XSP_001921	ENOG4108606	TspO/MBR family
XSP_001922	ENOG4105CFH	Aspartokinase
XSP_001927	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
XSP_001928	ENOG4105CUT	histidyl-tRNA synthetase
XSP_001930	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
XSP_001931	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
XSP_001932	ENOG4105CIH	Imidazole acetol-phosphate transaminase
XSP_001933	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
XSP_001934	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
XSP_001935	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
XSP_001937	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
XSP_001942	ENOG4107QY0	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity)
XSP_001943	ENOG4105CUB	amino acid
XSP_001944	ENOG4105CUB	amino acid
XSP_001946	ENOG4108JQ1	Dehydrogenase
XSP_001947	ENOG4105CQB	FAD linked oxidase domain protein
XSP_001951	ENOG4105FUQ	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
XSP_001953	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
XSP_001956	ENOG4105CE1	Ferrous iron transport protein b
XSP_001959	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
XSP_001960	ENOG4108RPX	mosc domain containing protein
XSP_001962	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
XSP_001964	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
XSP_001965	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
XSP_001967	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
XSP_001972	ENOG4105CRK	lysyL-tRNA synthetase
XSP_001973	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
XSP_001974	ENOG4105BZU	Histidine kinase
XSP_001975	ENOG41060WC	Enoyl-CoA hydratase
XSP_001976	ENOG4105CEY	Amp-dependent synthetase and ligase
XSP_001978	ENOG4107QM5	aconitate hydratase
XSP_001981	ENOG4107QIJ	Aconitate hydratase 2
XSP_001982	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
XSP_001983	ENOG4105BZU	Histidine kinase
XSP_001984	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
XSP_001986	ENOG4105BZU	Histidine kinase
XSP_001987	ENOG4105C8Q	Methyl-accepting chemotaxis
XSP_001989	ENOG4108V3W	Chemotaxis protein, CheW
XSP_001991	ENOG4105C8Q	Methyl-accepting chemotaxis
XSP_001993	ENOG4105C8Q	Methyl-accepting chemotaxis
XSP_001994	ENOG4105C8Q	Methyl-accepting chemotaxis
XSP_001995	ENOG4105C8Q	Methyl-accepting chemotaxis
XSP_001997	ENOG4105C8Q	Methyl-accepting chemotaxis
XSP_002001	ENOG4105CBS	Chea signal transduction histidine kinase
XSP_002002	ENOG4108VYJ	response regulator receiver protein
XSP_002004	ENOG4108V3W	Chemotaxis protein, CheW
XSP_002006	ENOG4105ER2	Ompa motb domain protein
XSP_002007	ENOG4105E14	MotA TolQ exbB proton channel
XSP_002009	ENOG4105EJC	lysr family transcriptional regulator
XSP_002010	ENOG4105F27	Major Facilitator
XSP_002011	ENOG4105CHR	reductase
XSP_002023	ENOG4108VYJ	response regulator receiver protein
XSP_002024	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
XSP_002026	ENOG4105FZW	flagellar biosynthesis regulator FlhF
XSP_002027	ENOG4105D7B	Flagellar biosynthesis protein flha
XSP_002028	ENOG4105D00	flagellar biosynthetic protein flhB
XSP_002029	ENOG4105BZU	Histidine kinase
XSP_002030	ENOG4105BZU	Histidine kinase
XSP_002031	ENOG4105BZU	Histidine kinase
XSP_002032	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
XSP_002033	ENOG4105VS8	Flagellar biosynthetic protein fliq
XSP_002034	ENOG4105CN7	Flagellar biosynthetic protein FliP
XSP_002035	ENOG4105VTB	flagellar biosynthesis protein fliO
XSP_002036	ENOG4105DD5	Flagellar motor switch protein
XSP_002037	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
XSP_002041	ENOG4108JIR	Flagellum-specific ATP synthase
XSP_002043	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
XSP_002044	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
XSP_002045	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
XSP_002048	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
XSP_002054	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
XSP_002055	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
XSP_002056	ENOG4108P1X	synthase
XSP_002060	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
XSP_002061	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
XSP_002065	ENOG4105MQ3	flagellar protein FliS
XSP_002066	ENOG4107W9T	flagellar hook-associated
XSP_002067	ENOG4105I03	Flagellin
XSP_002070	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
XSP_002071	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
XSP_002073	ENOG4105CGA	flagellar basal-body rod protein FlgG
XSP_002074	ENOG4108KPB	Flagellar basal-body rod protein FlgF
XSP_002075	ENOG4105BZE	flagellar hook protein, FlgE
XSP_002076	ENOG410822I	Flagellar hook capping protein
XSP_002077	ENOG4108ZC9	flagellar basal-body rod protein flgc
XSP_002083	ENOG4105BZU	Histidine kinase
XSP_002084	ENOG4105BZU	Histidine kinase
XSP_002086	ENOG4105BZU	Histidine kinase
XSP_002089	ENOG41075W9	High frequency lysogenization protein HflD homolog
XSP_002090	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
XSP_002093	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
XSP_002094	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
XSP_002096	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
XSP_002098	ENOG4105C3M	thioredoxin reductase
XSP_002099	ENOG4105CNU	cell division protein FtsK
XSP_002102	ENOG4105D1H	recombination factor protein RarA
XSP_002103	ENOG41082MI	Protein CrcB homolog
XSP_002104	ENOG4105CHU	acetyl-coa acetyltransferase
XSP_002110	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
XSP_002112	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
XSP_002113	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
XSP_002114	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
XSP_002115	ENOG4105D06	uba thif-type nad fad binding protein
XSP_002118	ENOG4105CGK	Exodeoxyribonuclease III
XSP_002120	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
XSP_002121	ENOG41085AN	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
XSP_002123	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
XSP_002125	ENOG4105I5W	Transporter
XSP_002128	ENOG4108IFG	nitrite reductase, (NAD(P)H)
XSP_002131	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
XSP_002136	ENOG4105EJZ	Glucose-1-phosphate cytidylyltransferase
XSP_002138	ENOG4105D5U	fad dependent oxidoreductase
XSP_002151	ENOG4105CQZ	Histidine kinase
XSP_002160	ENOG410642W	LysR family Transcriptional regulator
XSP_002166	ENOG4105CC0	LysR family Transcriptional regulator
XSP_002168	ENOG4105FFC	UPF0187 protein
XSP_002173	ENOG4105EWI	Short-chain dehydrogenase reductase Sdr
XSP_002195	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
XSP_002197	ENOG4107W2A	UPF0173 metal-dependent hydrolase
XSP_002200	ENOG4105CUJ	penicillin amidase
XSP_002201	ENOG4105IBP	Cyclic peptide transporter
XSP_002206	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
XSP_002218	ENOG4105DUN	Mediates zinc uptake. May also transport other divalent cations (By similarity)
XSP_002219	ENOG4105EI2	Pseudouridine synthase
XSP_002220	ENOG4105C03	ribonuclease
XSP_002221	ENOG4105WH1	Two component transcriptional regulator luxr family
XSP_002224	ENOG4108V1T	peptidylprolyl cis-trans isomerase
XSP_002226	ENOG4107QQG	Dehydrogenase
XSP_002231	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
XSP_002232	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
XSP_002235	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
XSP_002237	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
XSP_002238	ENOG4105BZ1	(ABC) transporter
XSP_002241	ENOG4108EC8	DNA internalization-related competence protein ComEC
XSP_002243	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
XSP_002244	ENOG4105D60	lipoprotein releasing system transmembrane protein
XSP_002246	ENOG410681N	tpr repeat protein
XSP_002251	ENOG410612Q	succinate dehydrogenase (cytochrome b-556 subunit)
XSP_002253	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
XSP_002256	ENOG4105CHC	glucokinase (EC 2.7.1.2)
XSP_002258	ENOG4105C01	Dihydroxy-acid dehydratase
XSP_002259	ENOG4108UHU	Aldolase
XSP_002264	ENOG4105N7H	Cytochrome
XSP_002278	ENOG4105BZU	Histidine kinase
XSP_002279	ENOG4105BZM	domain protein
XSP_002284	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
XSP_002286	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
XSP_002293	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
XSP_002294	ENOG4108Z6B	deaminase
XSP_002295	ENOG4105KST	dependent repressor
XSP_002296	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
XSP_002301	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
XSP_002304	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
XSP_002306	ENOG4105ESV	Glycosyl transferase, family 4
XSP_002307	ENOG4105CFV	Tetratricopeptide repeat protein
XSP_002310	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
XSP_002311	ENOG4105CAT	Cytidine monophosphate kinase
XSP_002314	ENOG4105DWY	Agmatine deiminase
XSP_002320	ENOG4105DRS	transport system, permease
XSP_002321	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
XSP_002327	ENOG4105K9H	YciI-like protein
XSP_002328	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
XSP_002329	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
XSP_002330	ENOG4105FE9	pseudouridine synthase
XSP_002334	ENOG4105CHM	Aminotransferase
XSP_002335	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
XSP_002336	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
XSP_002337	ENOG41060IM	Heme exporter protein
XSP_002339	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
XSP_002340	ENOG4105DA4	cytochrome c-type biogenesis protein
XSP_002342	ENOG4105KWW	Biogenesis protein
XSP_002343	ENOG4108M1T	Cytochrome c-type biogenesis protein
XSP_002344	ENOG4105DWV	Homoserine O-trans-acetylase
XSP_002347	ENOG4108JJ8	(ABC) transporter
XSP_002348	ENOG4108JJ9	ABC, transporter
XSP_002349	ENOG4105C4M	(Ubiquinol oxidase) subunit I
XSP_002350	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
XSP_002361	ENOG4105CH7	arginosuccinase
XSP_002364	ENOG4105CAS	nag kinase
XSP_002366	ENOG4105CDH	Citrulline--aspartate ligase
XSP_002367	ENOG4105DBV	ornithine carbamoyltransferase
XSP_002369	ENOG4105C8N	cysteinyl-tRNA synthetase
XSP_002370	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
XSP_002374	ENOG4105CD3	dihydroorotase
XSP_002377	ENOG4105CPD	ethanolamine ammonia-lyase
XSP_002378	ENOG4107FQ9	ethanolamine ammonia-lyase
XSP_002387	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
XSP_002389	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
XSP_002391	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
XSP_002392	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
XSP_002393	ENOG4105BZU	Histidine kinase
XSP_002396	ENOG4105ECY	inositol monophosphatase
XSP_002397	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
XSP_002400	ENOG4105C5H	ABC transporter
XSP_002401	ENOG4105C1J	atp-dependent rna helicase
XSP_002402	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
XSP_002403	ENOG4105CNG	UPF0061 protein
XSP_002405	ENOG4108RXX	maleylacetoacetate isomerase
XSP_002406	ENOG4105VEQ	Cold shock protein
XSP_002407	ENOG4108UPT	UPF0178 protein
XSP_002408	ENOG4108VWS	Yaeq family
XSP_002409	ENOG4105CBX	hi0933 family
XSP_002412	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
XSP_002413	ENOG4105CHR	reductase
XSP_002417	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
XSP_002418	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
XSP_002420	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
XSP_002421	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
XSP_002424	ENOG4105E6M	Sulphatase-modifying factor protein
XSP_002429	ENOG4105BZU	Histidine kinase
XSP_002430	ENOG4108V3W	Chemotaxis protein, CheW
XSP_002431	ENOG4105C8Q	Methyl-accepting chemotaxis
XSP_002432	ENOG4108VX5	3-methyladenine DNA glycosylase
XSP_002433	ENOG4107QRT	dEAD DEAH box helicase
XSP_002435	ENOG4105KB2	stringent starvation protein b
XSP_002436	ENOG4107MKT	Stringent starvation protein a
XSP_002437	ENOG4105EIX	cytochrome c1
XSP_002438	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
XSP_002439	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
XSP_002440	ENOG4105E4C	Lytic transglycosylase catalytic
XSP_002443	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
XSP_002445	ENOG4105C9A	Phoh family
XSP_002447	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
XSP_002449	ENOG4108JU5	Magnesium and cobalt efflux protein
XSP_002454	ENOG4105D38	putrescine abc transporter
XSP_002455	ENOG4105F38	ABC transporter, permease
XSP_002456	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
XSP_002460	ENOG4107RUE	extracellular solute-binding protein family 1
XSP_002461	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
XSP_002464	ENOG4105CFQ	glutamine synthetase
XSP_002465	ENOG4105CJP	fad dependent oxidoreductase
XSP_002467	ENOG4105CSH	Transporter
XSP_002469	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
XSP_002474	ENOG4106BRA	Membrane
XSP_002475	ENOG4105BZU	Histidine kinase
XSP_002476	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
XSP_002477	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
XSP_002479	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
XSP_002481	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
XSP_002482	ENOG4105C7I	Dehydrogenase
XSP_002484	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
XSP_002485	ENOG4105BZS	acriflavin resistance protein
XSP_002486	ENOG4105ETE	Transcriptional regulator (LacI family
XSP_002487	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
XSP_002488	ENOG4105DE4	1-phosphofructokinase
XSP_002489	ENOG4105DM4	PTS System
XSP_002497	ENOG4107QT7	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
XSP_002498	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
XSP_002499	ENOG4105VIE	preprotein translocase, subunit YajC
XSP_002501	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
XSP_002509	ENOG4105E08	Glycoside hydrolase, family 9
XSP_002510	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
XSP_002511	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
XSP_002513	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
XSP_002514	ENOG4106H78	methyltransferase
XSP_002515	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
XSP_002517	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
XSP_002524	ENOG4107QTZ	amino acid
XSP_002527	ENOG4105DC7	peptidase M24
XSP_002529	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
XSP_002532	ENOG41080HI	glycine oxidase
XSP_002533	ENOG4105CTU	Proline racemase
XSP_002535	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
XSP_002537	ENOG4105CEN	a g-specific adenine glycosylase
XSP_002539	ENOG4105CQZ	Histidine kinase
XSP_002546	ENOG4105CSU	acyl-Coa dehydrogenase
XSP_002548	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
XSP_002552	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
XSP_002553	ENOG4108JMX	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
XSP_002554	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
XSP_002559	ENOG4108NQK	Catalyzes the transfer of a glucuronic acid (GlcA) residue from UDP-glucuronate to mannose-alpha-1,3-glucose-beta- 1,4-glucose-P-P-polyisoprenyl to form the lipid-linked tetrasaccharide GlcA-Man-Glc(2)-PP-Pol, with a glucuronic acid- beta-mannose linkage. Is involved in the biosynthesis of the exopolysaccharide xanthan, since it catalyzes the fourth glycosylation step in the assembly of the pentasaccharide-P-P- polyisoprenyl repeating unit of xanthan. Is unable to use the trisaccharide acceptor freed from the pyrophosphate lipid moiety. Does not show specificity for the lipidic portion of the acceptor. Shows diminished activity when tested with 6-O-acetyl-mannose- alpha-1,3-glucose-beta-1,4-glucose-P-P-polyisoprenyl, a
XSP_002561	ENOG4107Y2G	Glycosyl transferase (Group 1
XSP_002562	ENOG4107UFF	group 1 glycosyl transferase
XSP_002566	ENOG4105D3Q	Sugar transferase
XSP_002570	ENOG4105WJX	transcriptional regulator MERR family
XSP_002572	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
XSP_002573	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
XSP_002576	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
XSP_002577	ENOG4105C22	threonyL-tRNA synthetase
XSP_002578	ENOG4105ETE	Transcriptional regulator (LacI family
XSP_002584	ENOG4105CG3	alpha amylase, catalytic region
XSP_002586	ENOG4106E4H	Type IV secretory pathway VirB3 family protein
XSP_002590	ENOG4105CMA	conjugation trbi family protein
XSP_002606	ENOG4105EWT	decarboxylase family
XSP_002607	ENOG4108KPZ	tonB-dependent Receptor
XSP_002608	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
XSP_002610	ENOG4105M2J	Glutaredoxin
XSP_002611	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
XSP_002612	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
XSP_002613	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
XSP_002615	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
XSP_002619	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
XSP_002620	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
XSP_002621	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
XSP_002622	ENOG4105CHV	Transcription elongation factor NusA
XSP_002623	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
XSP_002625	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
XSP_002626	ENOG4105C8S	subunit m
XSP_002630	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
XSP_002632	ENOG4107R0R	NADH dehydrogenase subunit g
XSP_002633	ENOG4107QIZ	NADH dehydrogenase
XSP_002634	ENOG4105GKE	subunit e
XSP_002636	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
XSP_002638	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
XSP_002641	ENOG4105CP7	Triose-phosphate isomerase
XSP_002642	ENOG4105EMU	Dehydrogenase
XSP_002645	ENOG4105BZU	Histidine kinase
XSP_002648	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
XSP_002658	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
XSP_002659	ENOG4105C5I	Dehydrogenase
XSP_002660	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
XSP_002662	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
XSP_002664	ENOG4105DJ4	phosphatidylserine decarboxylase
XSP_002666	ENOG4105D7A	ATP-binding protein
XSP_002668	ENOG4107VIJ	nudix hydrolase
XSP_002671	ENOG4108RRZ	Transcription elongation factor GreB
XSP_002673	ENOG41067QW	Transcriptional regulator
XSP_002675	ENOG4106A2Z	transcriptional regulator antitoxin, MazE
XSP_002685	ENOG4105DHP	deoxycytidine triphosphate deaminase
XSP_002686	ENOG4105D1F	ATP-binding protein
XSP_002689	ENOG4105C9K	Endothelin-converting enzyme 1
XSP_002690	ENOG4105C9K	Endothelin-converting enzyme 1
XSP_002694	ENOG4105DC8	reductase
XSP_002695	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
XSP_002698	ENOG4108YZY	peptidylprolyl cis-trans isomerase
XSP_002699	ENOG4105K4H	Nlp p60 protein
XSP_002700	ENOG4105K4H	Nlp p60 protein
XSP_002704	ENOG4105CK2	sodium dicarboxylate symporter
XSP_002705	ENOG4105G6Z	alkaline phosphatase
XSP_002706	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
XSP_002707	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
XSP_002708	ENOG4105CTB	Polyprenyl synthetase
XSP_002711	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
XSP_002712	ENOG4105N42	UPF0307 protein
XSP_002713	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
XSP_002715	ENOG4105QD6	exported protein
XSP_002716	ENOG4105C03	ribonuclease
XSP_002717	ENOG4108Z03	MAF-like protein
XSP_002718	ENOG4105MPN	Membrane
XSP_002720	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
XSP_002724	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
XSP_002727	ENOG4105C8T	Leucyl-tRNA synthetase
XSP_002729	ENOG4107QR8	Thioredoxin
XSP_002739	ENOG4105BZ1	(ABC) transporter
XSP_002742	ENOG4105FQP	Beta-lactamase
XSP_002743	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
XSP_002747	ENOG4105FE9	pseudouridine synthase
XSP_002748	ENOG4105BZU	Histidine kinase
XSP_002750	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
XSP_002760	ENOG4105D03	DNA-3-methyladenine glycosylase II
XSP_002766	ENOG4105UGU	tonB-dependent Receptor
XSP_002768	ENOG4105CPC	Aldo Keto reductase
XSP_002769	ENOG4105F27	Major Facilitator
XSP_002770	ENOG4105EJC	lysr family transcriptional regulator
XSP_002772	ENOG4105CF7	AraC family transcriptional regulator
XSP_002774	ENOG4105EQ2	LysR family Transcriptional regulator
XSP_002776	ENOG4108JGH	Tetr family transcriptional regulator
XSP_002777	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
XSP_002778	ENOG4105BZS	acriflavin resistance protein
XSP_002779	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
XSP_002781	ENOG4105MYN	Zinc uptake regulation protein
XSP_002782	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
XSP_002787	ENOG4105CT7	inner membrane cred family protein
XSP_002791	ENOG4105EB3	Histidine kinase
XSP_002792	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
XSP_002793	ENOG4105D6S	protein involved in catabolism of external DNA
XSP_002795	ENOG4108JA2	transcriptioN-repair coupling factor
XSP_002797	ENOG4105CBS	Chea signal transduction histidine kinase
XSP_002799	ENOG4108V3W	Chemotaxis protein, CheW
XSP_002800	ENOG4105BZU	Histidine kinase
XSP_002801	ENOG4105BZU	Histidine kinase
XSP_002802	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
XSP_002803	ENOG4107RZC	phospholipase d
XSP_002804	ENOG4105C9K	Endothelin-converting enzyme 1
XSP_002806	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
XSP_002807	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
XSP_002808	ENOG4105EUB	pirin domain protein
XSP_002810	ENOG4105EUB	pirin domain protein
XSP_002811	ENOG4105D22	carbon starvation protein
XSP_002812	ENOG4105VCD	cytoplasmic protein
XSP_002813	ENOG4107YBY	Hydrolase
XSP_002819	ENOG4107XAN	XdhC and CoxI family
XSP_002820	ENOG4105C7W	Xanthine dehydrogenase
XSP_002821	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
XSP_002822	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
XSP_002825	ENOG4108UUM	single-stranded DNA-binding protein
XSP_002826	ENOG4105EAH	synthase
XSP_002828	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
XSP_002831	ENOG4105CFH	Aspartokinase
XSP_002833	ENOG4105JAB	phenazine biosynthesis protein, phzf family
XSP_002835	ENOG4108Z9K	Osmotically inducible protein
XSP_002837	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
XSP_002838	ENOG4108UJU	UPF0301 protein
XSP_002839	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
XSP_002843	ENOG4105CZX	twitching motility protein
XSP_002844	ENOG4105CZX	twitching motility protein
XSP_002845	ENOG4105DFA	alanine racemase domain protein
XSP_002846	ENOG4105II7	pyrroline-5-carboxylate reductase
XSP_002848	ENOG4108K5P	(LipO)protein
XSP_002852	ENOG4108Z0Z	intracellular protease Pfpi family
XSP_002856	ENOG4105C3K	feS assembly ATPase SufC
XSP_002857	ENOG4105JRK	feS assembly protein SufD
XSP_002858	ENOG4105C9B	Cysteine desulfurase
XSP_002860	ENOG4105VQD	rieske 2fe-2S domain-containing protein
XSP_002861	ENOG4108ESX	Receptor
XSP_002862	ENOG4107E2E	PKHD-type hydroxylase
XSP_002867	ENOG4105CJ2	(LipO)protein
XSP_002870	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
XSP_002871	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
XSP_002873	ENOG4105EHM	Aminoglycoside phosphotransferase
XSP_002874	ENOG4108S0S	Nucleotidyl transferase
XSP_002876	ENOG4105C02	permease
XSP_002880	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
XSP_002884	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
XSP_002886	ENOG4105C2X	Arabinose 5-phosphate isomerase
XSP_002887	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
XSP_002889	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
XSP_002890	ENOG4108IUZ	ABC transporter
XSP_002891	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
XSP_002892	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
XSP_002893	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
XSP_002897	ENOG41080Z8	PHOSPHOCARRIER protein
XSP_002898	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
XSP_002899	ENOG4105CJW	magnesium transporter
XSP_002900	ENOG4107UWA	esterase
XSP_002901	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
XSP_002902	ENOG4105C4M	(Ubiquinol oxidase) subunit I
XSP_002903	ENOG4105C85	amino acid
XSP_002904	ENOG4108NFF	pectate lyase
XSP_002907	ENOG4105CUB	amino acid
XSP_002908	ENOG4108MHS	Lysyl endopeptidase
XSP_002911	ENOG4105QV4	Tryptophan halogenase
XSP_002916	ENOG4108Z4X	TRANSCRIPTIONal
XSP_002918	ENOG4106032	Glutathionylspermidine synthase
XSP_002923	ENOG4108P9J	Phage shock protein A
XSP_002925	ENOG4105M4B	Catalyzes the transfer of an acetyl group from acetyl- CoA to the 6'-amino group of aminoglycoside molecules conferring resistance to antibiotics containing the purpurosamine ring (By similarity)
XSP_002926	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
XSP_002927	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
XSP_002928	ENOG4105D49	3-dehydroquinate synthase
XSP_002930	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
XSP_002944	ENOG4108JUA	Transcriptional regulator
XSP_002945	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
XSP_002946	ENOG4105BZU	Histidine kinase
XSP_002947	ENOG4105BZU	Histidine kinase
XSP_002948	ENOG4108YYC	ycei family
XSP_002949	ENOG4105CPW	cytochrome b561
XSP_002952	ENOG4105EJQ	L-serine dehydratase
XSP_002954	ENOG4105CFH	Aspartokinase
XSP_002955	ENOG4105C28	cystathionine
XSP_002956	ENOG4106TYC	homoserine o-acetyltransferase (EC 2.3.1.31)
XSP_002957	ENOG4105DR5	peptidase
XSP_002958	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
XSP_002959	ENOG4108UT2	hemolysin iii
XSP_002960	ENOG41066T0	asmA family
XSP_002961	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
XSP_002963	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
XSP_002964	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
XSP_002966	ENOG4105D05	Receptor
XSP_002967	ENOG4108IG5	Transcriptional regulator
XSP_002969	ENOG4107QPN	acyl-Coa dehydrogenase
XSP_002976	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
XSP_002977	ENOG4105KK4	UPF0060 membrane protein
XSP_002979	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
XSP_002980	ENOG4107RK2	ADP-ribose diphosphatase NudE
XSP_002982	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
XSP_002983	ENOG4105CHC	glucokinase (EC 2.7.1.2)
XSP_002986	ENOG4105VRS	hydrolase family 18
XSP_002987	ENOG4105E2D	ec 3.2.1.52
XSP_002991	ENOG4105CWX	Alpha-1,2-mannosidase
XSP_002996	ENOG4106N3A	copper homeostasis protein cutc
XSP_002998	ENOG4105D9U	N-acetyltransferase
XSP_003000	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
XSP_003002	ENOG4105C8Q	Methyl-accepting chemotaxis
XSP_003004	ENOG4105M3Z	response regulator
XSP_003005	ENOG4108UNF	response regulator
XSP_003006	ENOG4105D7Z	glutathione synthase
XSP_003008	ENOG41065RQ	ADP-ribosylation crystallin J1
XSP_003009	ENOG41072GX	Peptidase M22 Glycoprotease
XSP_003010	ENOG4105DVT	helicase
XSP_003012	ENOG4105BZ4	penicillin-binding protein
XSP_003015	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
XSP_003017	ENOG410698T	Required for coenzyme pyrroloquinoline quinone (PQQ) biosynthesis. PQQ is probably formed by cross-linking a specific glutamate to a specific tyrosine residue and excising these residues from the peptide (By similarity)
XSP_003019	ENOG41086XE	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ (By similarity)
XSP_003020	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
XSP_003023	ENOG4105CHC	glucokinase (EC 2.7.1.2)
XSP_003026	ENOG4105CQ7	ATP-dependent helicase
XSP_003028	ENOG4105C9U	ATP-dependent DNA helicase RecQ
XSP_003042	ENOG4107S5I	aldo keto reductase
XSP_003043	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
XSP_003045	ENOG4105KCK	Peptidoglycan-associated lipoprotein
XSP_003046	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
XSP_003049	ENOG4105E02	MotA TolQ exbB proton channel
XSP_003050	ENOG4107YD3	Thioesterase
XSP_003052	ENOG4105DFH	Transport of potassium into the cell (By similarity)
XSP_003061	ENOG4108ISG	Major Facilitator
XSP_003063	ENOG4105HSS	phospholipase C
XSP_003065	ENOG4105ETT	transcriptional Regulator, LysR family
XSP_003066	ENOG4105C5H	ABC transporter
XSP_003067	ENOG4107RNH	Outer membrane receptor FepA
XSP_003069	ENOG4107RNH	Outer membrane receptor FepA
XSP_003070	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
XSP_003072	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
XSP_003074	ENOG4105GAV	receptor
XSP_003077	ENOG4105C6X	Major Facilitator
XSP_003078	ENOG4105DBM	Siderophore biosynthesis protein
XSP_003079	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
XSP_003082	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
XSP_003084	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
XSP_003087	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
XSP_003088	ENOG4105E2Y	ABC, transporter
XSP_003089	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
XSP_003090	ENOG4105GVF	(ABC) transporter
XSP_003091	ENOG4105CPC	Aldo Keto reductase
XSP_003093	ENOG4107ZSV	Receptor
XSP_003094	ENOG41082IR	Excinuclease ABC C subunit domain protein
XSP_003102	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
XSP_003103	ENOG4108K4C	ec 3.1.3.12
XSP_003104	ENOG4105BZP	glycoside hydrolase 15-related
XSP_003105	ENOG4105C1K	alpha-alpha-trehalose-phosphate synthase
XSP_003106	ENOG4105DZG	Dehydrogenase
XSP_003107	ENOG4105C8Q	Methyl-accepting chemotaxis
XSP_003108	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
XSP_003109	ENOG4105C34	Pseudouridine synthase
XSP_003110	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XSP_003112	ENOG4105C4K	Nad synthetase
XSP_003114	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
XSP_003115	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
XSP_003116	ENOG4107TUY	Histidine kinase
XSP_003117	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
XSP_003118	ENOG4107QHF	type ii secretion system protein e
XSP_003119	ENOG4105KHS	type IV fimbrial pilin protein
XSP_003120	ENOG4105D7Q	type ii secretion system
XSP_003121	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
XSP_003122	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
XSP_003124	ENOG4105BZU	Histidine kinase
XSP_003125	ENOG4105ETX	regulatoR
XSP_003127	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
XSP_003132	ENOG4105C8Q	Methyl-accepting chemotaxis
XSP_003133	ENOG4108V1U	phospholipid-binding protein
XSP_003135	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
XSP_003136	ENOG4107QPK	)-transporter
XSP_003141	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
XSP_003146	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
XSP_003148	ENOG4105ETE	Transcriptional regulator (LacI family
XSP_003153	ENOG4105C2N	RNA methyltransferase TrmH family group 3
XSP_003156	ENOG4105CD8	aminopeptidase N
XSP_003157	ENOG4105BZS	acriflavin resistance protein
XSP_003158	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
XSP_003159	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
XSP_003161	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
XSP_003162	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
XSP_003167	ENOG4105BZU	Histidine kinase
XSP_003169	ENOG4107R11	Transcriptional regulator
XSP_003170	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
XSP_003172	ENOG4108UVJ	appr-1-p processing domain protein
XSP_003173	ENOG4107R1Y	fructose-bisphosphate aldolase
XSP_003174	ENOG4105CA9	Pyruvate kinase
XSP_003180	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
XSP_003183	ENOG4105EIF	outer membrane protein W
XSP_003185	ENOG4107S76	domain protein
XSP_003186	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
XSP_003187	ENOG4105E0C	molybdate abc transporter
XSP_003188	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
XSP_003196	ENOG4107Y2H	ErfK ybiS ycfS ynhG family protein
XSP_003197	ENOG4105DR5	peptidase
XSP_003198	ENOG4105CHR	reductase
XSP_003199	ENOG4105CBN	LysR family transcriptional regulator
XSP_003200	ENOG4105CNM	Receptor
XSP_003201	ENOG4105CV1	Transketolase (EC 2.2.1.1)
XSP_003202	ENOG4105CK2	sodium dicarboxylate symporter
XSP_003209	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
XSP_003210	ENOG4105E4G	Type IV pilus
XSP_003215	ENOG4108JQC	penicillin-binding protein 1A
XSP_003219	ENOG4105DU0	nucleoside hydrolase
XSP_003220	ENOG4105CB5	ATP-dependent DNA helicase recG
XSP_003221	ENOG4105KME	endoribonuclease L-psp
XSP_003222	ENOG4105CTX	dehydratase
XSP_003223	ENOG4105EPF	Outer membrane porin
XSP_003225	ENOG4105DJB	Major Facilitator Superfamily
XSP_003229	ENOG4107RSM	transcriptional regulator
XSP_003230	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
XSP_003232	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
XSP_003233	ENOG4105DSJ	YicC domain protein
XSP_003234	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
XSP_003236	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
XSP_003237	ENOG4105CSA	Coproporphyrinogen iii oxidase
XSP_003240	ENOG4105D9Y	Splits dipeptides with a prolyl residue in the C- terminal position (By similarity)
XSP_003242	ENOG4107RAQ	aminopeptidase
XSP_003245	ENOG4105W8B	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
XSP_003247	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
XSP_003251	ENOG41063JG	Transcriptional regulator
XSP_003252	ENOG4105VCQ	rubredoxin
XSP_003253	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
XSP_003256	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
XSP_003257	ENOG41061ZR	Transcriptional regulator
XSP_003258	ENOG41090JD	Blue (Type 1) copper domain protein
XSP_003259	ENOG4105CIH	Imidazole acetol-phosphate transaminase
XSP_003265	ENOG4105C8Y	Acetylornithine aminotransferase
XSP_003266	ENOG4105EYW	Ion transport protein
XSP_003271	ENOG410841Q	phosphoesterase PA-phosphatase related protein
XSP_003272	ENOG4105FFC	UPF0187 protein
XSP_003274	ENOG4105DFU	Cell wall formation (By similarity)
XSP_003275	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
XSP_003279	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
XSP_003281	ENOG4105F0N	pyrophosphate phospho-hydrolase
XSP_003283	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
XSP_003284	ENOG4105ECQ	AraC Family Transcriptional Regulator
XSP_003285	ENOG4108M3R	transcriptional activator CadC
XSP_003287	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
XSP_003289	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
XSP_003293	ENOG4105C7B	Threonine dehydratase
XSP_003294	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
XSP_003295	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
XSP_003296	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
XSP_003297	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
XSP_003298	ENOG4108MP6	LysR family Transcriptional regulator
XSP_003299	ENOG4105BZU	Histidine kinase
XSP_003301	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
XSP_003302	ENOG4105DFG	type I secretion outer membrane protein
XSP_003303	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
XSP_003304	ENOG4105D1S	lipid A biosynthesis
XSP_003309	ENOG4105C6K	Malic enzyme
XSP_003315	ENOG4105CPC	Aldo Keto reductase
XSP_003316	ENOG4105WH1	Two component transcriptional regulator luxr family
XSP_003317	ENOG4106JDA	Phosphoglycerate transport regulatory protein PGTC
XSP_003318	ENOG4105DHQ	Histidine kinase
XSP_003321	ENOG4105D4T	Citrate transporter
XSP_003322	ENOG4105CHR	reductase
XSP_003323	ENOG4105ETE	Transcriptional regulator (LacI family
XSP_003326	ENOG4107QW3	Sucrose phosphorylase
XSP_003334	ENOG4105CNM	Receptor
XSP_003339	ENOG41069H0	dihydroorotase EC 3.5.2.3
XSP_003340	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
XSP_003345	ENOG4108RMV	DegV Family
XSP_003347	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
XSP_003348	ENOG4107YIM	Involved in the transcription termination process (By similarity)
XSP_003350	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
XSP_003353	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
XSP_003356	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
XSP_003358	ENOG4105C5H	ABC transporter
XSP_003359	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
XSP_003372	ENOG4106S9K	Transcriptional regulator
XSP_003374	ENOG4105GVR	general secretion pathway protein D
XSP_003376	ENOG410678M	general secretion pathway protein M
XSP_003377	ENOG41090VX	general secretion pathway protein L
XSP_003378	ENOG4105UV2	general secretion pathway protein K
XSP_003379	ENOG41069G9	General secretion pathway protein J
XSP_003381	ENOG4105WMT	general secretion pathway protein h
XSP_003383	ENOG4105D7Q	type ii secretion system
XSP_003384	ENOG4107QHF	type ii secretion system protein e
XSP_003385	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
XSP_003386	ENOG4105EUR	Domain-Containing protein
XSP_003387	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
XSP_003388	ENOG4105EUR	Domain-Containing protein
XSP_003389	ENOG4108ETH	Formylglycinamide ribotide synthetase
XSP_003390	ENOG4105T95	Thiol disulfide interChange protein
XSP_003391	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
XSP_003393	ENOG4108K5H	permease YjgP YjgQ family protein
XSP_003402	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
XSP_003408	ENOG4105DHJ	ABC, transporter
XSP_003409	ENOG4108SNX	Mammalian cell entry related domain protein
XSP_003412	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
XSP_003415	ENOG4107QP7	CoA-transferase subunit A
XSP_003416	ENOG4107QKV	phosphomannomutase
XSP_003417	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
XSP_003418	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
XSP_003419	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
XSP_003422	ENOG4105BZJ	Electron transfer flavoprotein
XSP_003423	ENOG4105C10	Electron transfer flavoprotein
XSP_003424	ENOG4105C28	cystathionine
XSP_003435	ENOG4105CZX	twitching motility protein
XSP_003436	ENOG4108RXX	maleylacetoacetate isomerase
XSP_003439	ENOG4105C1J	atp-dependent rna helicase
XSP_003441	ENOG4105D05	Receptor
XSP_003442	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
XSP_003444	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
XSP_003447	ENOG4105NIV	Esterase
XSP_003448	ENOG4107RNH	Outer membrane receptor FepA
XSP_003449	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
XSP_003450	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
XSP_003453	ENOG4105DGW	oligopeptidase A
XSP_003460	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
XSP_003461	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
XSP_003462	ENOG4105C19	ABC transporter
XSP_003463	ENOG4107RBB	ABC transporter, permease
XSP_003466	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
XSP_003470	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
XSP_003477	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
XSP_003478	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
XSP_003479	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
XSP_003480	ENOG4107RAZ	it plays a direct role in the translocation of protons across the membrane (By similarity)
XSP_003484	ENOG4107QN2	dihydrolipoyl dehydrogenase
XSP_003486	ENOG4107QSN	dihydrolipoamide acetyltransferase
XSP_003492	ENOG4105D01	(LipO)protein
XSP_003493	ENOG4108UMI	ABC transporter, permease
XSP_003494	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
XSP_003495	ENOG4105DJP	Membrane
XSP_003496	ENOG4108VPT	UPF0234 protein
XSP_003498	ENOG4105BZU	Histidine kinase
XSP_003501	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
XSP_003502	ENOG4105I08	Pseudouridine synthase
XSP_003507	ENOG4105I8F	Histidine kinase
XSP_003511	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
XSP_003512	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
XSP_003513	ENOG4105EW9	transcriptional regulator AsnC family
XSP_003516	ENOG4107RD7	Flagellar Motor Protein, MotA
XSP_003517	ENOG4105ER2	Ompa motb domain protein
XSP_003522	ENOG4105E3A	(ABC) transporter
XSP_003523	ENOG4105DA5	(ABC) transporter
XSP_003524	ENOG4105EEQ	Na H antiporter
XSP_003527	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
XSP_003529	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
XSP_003531	ENOG4105CC0	LysR family Transcriptional regulator
XSP_003533	ENOG4105CPC	Aldo Keto reductase
XSP_003535	ENOG4105C9K	Endothelin-converting enzyme 1
XSP_003538	ENOG4107QTZ	amino acid
XSP_003540	ENOG4108VAC	response regulator
XSP_003541	ENOG4105C2F	Histidine kinase
XSP_003544	ENOG4108Z9Z	response to DNA damage stimulus
XSP_003545	ENOG4105WEF	catalase
XSP_003547	ENOG4105BZU	Histidine kinase
XSP_003550	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
XSP_003552	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
XSP_003554	ENOG4105E2A	Dehydrogenase
XSP_003566	ENOG4105DA5	(ABC) transporter
XSP_003570	ENOG4105C8Q	Methyl-accepting chemotaxis
XSP_003577	ENOG4105CHH	sulfate transporter
XSP_003578	ENOG4105CMQ	Chloride channel
XSP_003582	ENOG4108IND	Tetr family transcriptional regulator
XSP_003584	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
XSP_003585	ENOG4108JGH	Tetr family transcriptional regulator
XSP_003591	ENOG4105K56	Transcriptional regulator
XSP_003600	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
XSP_003601	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
XSP_003603	ENOG4108Z7F	N-acetyltransferase
XSP_003604	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
XSP_003611	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
XSP_003612	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
XSP_003613	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
XSP_003614	ENOG4108WZM	domain protein
XSP_003615	ENOG4105C79	DNA protecting protein DprA
XSP_003619	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
XSP_003623	ENOG4107ZQV	short-chain dehydrogenase reductase
XSP_003625	ENOG4105D07	Signal peptide peptidase, SppA
XSP_003626	ENOG4107QI1	Mate efflux family protein
XSP_003629	ENOG4105C25	Primosomal protein n'
XSP_003630	ENOG4108TGY	Glutathione S-transferase
XSP_003634	ENOG4105EN6	Membrane
XSP_003635	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
XSP_003637	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
XSP_003638	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
XSP_003639	ENOG4105CAK	Cell division ATP-binding protein ftsE
XSP_003642	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
XSP_003643	ENOG4105VS7	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity)
XSP_003644	ENOG4105E9K	Isocitrate dehydrogenase
XSP_003647	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
XSP_003648	ENOG4105CH2	amidohydrolase
XSP_003650	ENOG4105BZS	acriflavin resistance protein
XSP_003652	ENOG4105E32	cytoplasmic protein
XSP_003660	ENOG4108UQS	dipeptidase
XSP_003663	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
XSP_003665	ENOG4105DTQ	mandelate racemase muconate lactonizing
XSP_003667	ENOG4105D5Q	Arginine ornithine antiporter
XSP_003671	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
XSP_003672	ENOG4107ZVW	dihydroneopterin aldolase
XSP_003675	ENOG4105KTH	gatB Yqey
XSP_003676	ENOG4107S2Z	UPF0761 membrane protein
XSP_003677	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
XSP_003678	ENOG4105DHU	Bile acid
XSP_003680	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
XSP_003685	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
XSP_003686	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
XSP_003689	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
XSP_003691	ENOG4105C26	Dehydrogenase
XSP_003697	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
XSP_003698	ENOG4105DR5	peptidase
XSP_003699	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
XSP_003701	ENOG4105EYM	Major Facilitator superfamily
XSP_003702	ENOG4105CGK	Exodeoxyribonuclease III
XSP_003705	ENOG4107QJE	Chromosome Partitioning Protein
XSP_003706	ENOG4105FA0	parb-like partition protein
XSP_003710	ENOG4105CKK	Glycosyl transferase, family 2
XSP_003713	ENOG4107QKV	phosphomannomutase
XSP_003715	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
XSP_003717	ENOG4105C75	arginyL-tRNA synthetase
XSP_003720	ENOG4105EMU	Dehydrogenase
XSP_003721	ENOG4105EXC	Acyl-transferase
XSP_003723	ENOG4105CEY	Amp-dependent synthetase and ligase
XSP_003725	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
XSP_003726	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
XSP_003730	ENOG4108YZA	Nitrogen regulatory protein pii
XSP_003731	ENOG4105W0Z	cytoplasmic protein
XSP_003732	ENOG4105C0P	Mg chelatase subunit ChlI
XSP_003735	ENOG41066DG	(EAL) domain protein
XSP_003738	ENOG4105EJ2	Transcriptional regulator
XSP_003746	ENOG4105ECP	epimerase
XSP_003747	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
XSP_003748	ENOG4105DHQ	Histidine kinase
XSP_003752	ENOG4105C0H	protease
XSP_003756	ENOG4105C02	permease
XSP_003757	ENOG4105DFC	had-superfamily hydrolase, subfamily ia, variant
XSP_003758	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
XSP_003762	ENOG4108S01	response regulator
XSP_003763	ENOG4108ZGX	Histidine kinase
XSP_003764	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
XSP_003765	ENOG4105C19	ABC transporter
XSP_003770	ENOG4105FDR	Membrane
XSP_003774	ENOG4105C31	Tryptophanyl-tRNA synthetase
XSP_003775	ENOG4105VDW	Csbd family
XSP_003787	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
XSP_003792	ENOG4105EB3	Histidine kinase
XSP_003793	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
XSP_003795	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
XSP_003798	ENOG4105CH6	catalase
XSP_003800	ENOG4105DVT	helicase
XSP_003806	ENOG4105D52	delta-aminolevulinic acid dehydratase
XSP_003818	ENOG4105CYM	Glutathione S-transferase
XSP_003822	ENOG4105QV4	Tryptophan halogenase
XSP_003825	ENOG4108IUW	ABC transporter
XSP_003827	ENOG4105VZ8	Transcriptional regulator
XSP_003846	ENOG4105DA5	(ABC) transporter
XSP_003847	ENOG4105E3A	(ABC) transporter
XSP_003848	ENOG41063V1	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
XSP_003853	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
XSP_003854	ENOG4107QYD	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
XSP_003856	ENOG4105CD5	CoA-binding domain protein
XSP_003860	ENOG4105CJW	magnesium transporter
XSP_003861	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
XSP_003862	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
XSP_003863	ENOG4105BZP	glycoside hydrolase 15-related
XSP_003867	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
XSP_003872	ENOG4105C2D	reductase
XSP_003878	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
XSP_003879	ENOG4105E9Q	Acyl-transferase
XSP_003881	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
XSP_003888	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
XSP_003889	ENOG4105C2M	dna polymerase I
XSP_003896	ENOG4105C4R	Atp-dependent dna helicase
XSP_003898	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
XSP_003900	ENOG4105JSC	dimethylmenaquinone methyltransferase
XSP_003902	ENOG4105KHM	amidohydrolase 2
XSP_003906	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
XSP_003910	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
XSP_003912	ENOG4105DGI	Alkaline phosphatase
XSP_003920	ENOG41061DF	Catalyzes the phosphorylation of N-acetylmannosamine (ManNAc) to ManNAc-6-P (By similarity)
XSP_003922	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
XSP_003924	ENOG4107QN1	sodium solute
XSP_003927	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
XSP_003932	ENOG4105DSG	hydrolase family 43
XSP_003936	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
XSP_003937	ENOG4105ERH	Fumarylacetoacetate hydrolase
XSP_003938	ENOG4105DIA	mandelate racemase muconate lactonizing
XSP_003939	ENOG4105QJH	Domain of unknown function (DUF718)
XSP_003940	ENOG4105EDR	glucose galactose transporter
XSP_003941	ENOG4108K2P	TRANSCRIPTIONal
XSP_003942	ENOG4108UI1	Probably functions as a manganese efflux pump (By similarity)
XSP_003943	ENOG4108UI1	Probably functions as a manganese efflux pump (By similarity)
XSP_003944	ENOG4105BZU	Histidine kinase
XSP_003945	ENOG4105E2V	Glycosyltransferase 36
XSP_003946	ENOG4105CT4	transporter
XSP_003947	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
XSP_003952	ENOG4105MA0	exported protein
XSP_003953	ENOG4105CFU	surface antigen
XSP_003954	ENOG4105D05	Receptor
XSP_003955	ENOG4107RDJ	Sulfotransferase
XSP_003958	ENOG4107QHF	type ii secretion system protein e
XSP_003959	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
XSP_003961	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
XSP_003962	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
XSP_003965	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
XSP_003968	ENOG4105DH7	May be involved in recombination (By similarity)
XSP_003969	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
XSP_003970	ENOG4105C93	Xylose Isomerase
XSP_003971	ENOG4105ETE	Transcriptional regulator (LacI family
XSP_003972	ENOG4105D0H	Alpha-glucuronidase (EC 3.2.1.139)
XSP_003974	ENOG4105CXK	mandelate racemase muconate lactonizing
XSP_003977	ENOG4105DEI	Mannitol dehydrogenase
XSP_003981	ENOG4105C5I	Dehydrogenase
XSP_003988	ENOG4105D9F	endo-1,4-beta-xylanase (EC 3.2.1.8)
XSP_003989	ENOG4105CNT	hydrolase family 2
XSP_003990	ENOG4105D2H	Uronic isomerase
XSP_003994	ENOG4105CT4	transporter
XSP_003995	ENOG4105DT9	hydrolase family 43
XSP_004000	ENOG4105E55	glycerol-3-phosphate acyltransferase
XSP_004002	ENOG4105ETE	Transcriptional regulator (LacI family
XSP_004005	ENOG4105QV4	Tryptophan halogenase
XSP_004006	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
XSP_004007	ENOG4105CUR	5'-nucleotidase, lipoprotein e(p4) family
XSP_004008	ENOG4108YXG	UPF0502 protein
XSP_004011	ENOG4105KNA	-acetyltransferase
XSP_004012	ENOG4105C4R	Atp-dependent dna helicase
XSP_004013	ENOG4107104	thymidine kinase
XSP_004014	ENOG4105BZU	Histidine kinase
XSP_004015	ENOG4105DJ9	glucan biosynthesis protein
XSP_004017	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
XSP_004023	ENOG4105DKK	Benzoate
XSP_004030	ENOG4105DSB	aldose 1-epimerase
XSP_004033	ENOG4105EJ9	Membrane
XSP_004034	ENOG4105E0K	tonB-dependent siderophore receptor
XSP_004038	ENOG4105EUJ	GTP cyclohydrolase i
XSP_004040	ENOG4105ZQC	membrane protein AaeX
XSP_004041	ENOG4105Y49	secretion protein, HlyD family
XSP_004043	ENOG4105DR8	Membrane
XSP_004044	ENOG4105CSH	Transporter
XSP_004047	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
XSP_004070	ENOG4107QYX	exodeoxyribonuclease v alpha
XSP_004071	ENOG4107QKA	exodeoxyribonuclease V beta
XSP_004072	ENOG4105DSY	exodeoxyribonuclease V, gamma
XSP_004077	ENOG410870W	N-acetyltransferase
XSP_004079	ENOG4105DHJ	ABC, transporter
XSP_004080	ENOG4105CY3	ABC transporter, permease
XSP_004081	ENOG4107PE3	Mammalian cell entry related domain protein
XSP_004084	ENOG410903C	(LipO)protein
XSP_004086	ENOG4108V06	Glutathione peroxidase
XSP_004088	ENOG4107QSV	RmuC domain protein
XSP_004089	ENOG4105CIS	alcohol dehydrogenase
XSP_004092	ENOG4108TGY	Glutathione S-transferase
XSP_004094	ENOG4105CUB	amino acid
XSP_004095	ENOG4105CWX	Alpha-1,2-mannosidase
XSP_004097	ENOG4105BZU	Histidine kinase
XSP_004098	ENOG4108IXP	Carbohydrate diacid transcriptional activator CdaR
XSP_004099	ENOG4105BZW	Glycerate kinase
XSP_004100	ENOG4105CSP	Major Facilitator Superfamily
XSP_004104	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
XSP_004108	ENOG4105DR4	Methyltransferase
XSP_004109	ENOG4105DU1	integral membrane protein, terc
XSP_004111	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
XSP_004116	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
XSP_004134	ENOG4106H6R	UPF0380 protein
XSP_004156	ENOG4105CMA	conjugation trbi family protein