locus-tag	class	description
LZE81_00010	COG0592	DNA-directed DNA polymerase activity
LZE81_00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LZE81_00020	COG0187	DNA topoisomerase II activity
LZE81_00025	COG1266	CAAX protease self-immunity
LZE81_00030	COG0501	Belongs to the peptidase M48B family
LZE81_00060	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
LZE81_00070	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LZE81_00085	COG1280	lysine exporter protein (LysE YggA)
LZE81_00100	COG4772	TonB-dependent receptor
LZE81_00110	COG3284	Transcriptional regulator
LZE81_00115	COG1012	belongs to the aldehyde dehydrogenase family
LZE81_00155	COG1304	FMN binding
LZE81_00160	COG2186	Transcriptional regulator
LZE81_00180	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LZE81_00240	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LZE81_00260	COG4771	TonB-dependent receptor
LZE81_00305	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
LZE81_00320	COG3507	Belongs to the glycosyl hydrolase 43 family
LZE81_00325	COG1609	Transcriptional regulator
LZE81_00335	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
LZE81_00340	COG1028	Short-chain dehydrogenase reductase Sdr
LZE81_00355	COG3186	Phenylalanine-4-hydroxylase
LZE81_00360	COG1522	sequence-specific DNA binding
LZE81_00395	COG1752	Esterase of the alpha-beta hydrolase superfamily
LZE81_00410	COG0671	phosphoesterase, PA-phosphatase related
LZE81_00425	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LZE81_00460	COG1929	Belongs to the glycerate kinase type-1 family
LZE81_00470	COG0531	amino acid
LZE81_00475	COG4566	intracellular signal transduction
LZE81_00480	COG4191	Histidine kinase
LZE81_00500	COG1322	Protein conserved in bacteria
LZE81_00505	COG0386	Belongs to the glutathione peroxidase family
LZE81_00510	COG2853	Lipoprotein
LZE81_00525	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
LZE81_00530	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LZE81_00535	COG1127	ABC transporter
LZE81_00540	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
LZE81_00545	COG1074	ATP-dependent DNA helicase activity
LZE81_00550	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LZE81_00570	COG0537	adenosine 5'-monophosphoramidase activity
LZE81_00575	COG1074	ATP-dependent DNA helicase activity
LZE81_00585	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
LZE81_00640	COG0477	Major facilitator Superfamily
LZE81_00645	COG0302	gtp cyclohydrolase
LZE81_00670	COG0730	response to heat
LZE81_00685	COG2951	lytic endotransglycosylase activity
LZE81_00750	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
LZE81_00755	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
LZE81_00760	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
LZE81_00765	COG0493	'glutamate synthase
LZE81_00770	COG0067	glutamate synthase
LZE81_00770	COG0069	glutamate synthase activity
LZE81_00770	COG0070	glutamate synthase
LZE81_00815	COG1205	dead DEAH box helicase
LZE81_00815	COG1111	helicase
LZE81_00845	COG2271	Major facilitator Superfamily
LZE81_00895	COG2062	phosphohistidine phosphatase, SixA
LZE81_00905	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LZE81_00910	COG2050	protein possibly involved in aromatic compounds catabolism
LZE81_00920	COG2267	carboxylic ester hydrolase activity
LZE81_00930	COG1881	PFAM PEBP family protein
LZE81_00935	COG1968	undecaprenyl-diphosphatase activity
LZE81_00940	COG0174	glutamine synthetase
LZE81_00945	COG0347	Belongs to the P(II) protein family
LZE81_00950	COG0004	ammonium transporteR
LZE81_00955	COG3852	Histidine kinase
LZE81_00960	COG2204	response regulator
LZE81_00965	COG2032	superoxide dismutase activity
LZE81_00970	COG2032	superoxide dismutase activity
LZE81_00980	COG0183	Belongs to the thiolase family
LZE81_01020	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
LZE81_01025	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
LZE81_01035	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
LZE81_01045	COG0612	Peptidase, M16
LZE81_01055	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LZE81_01060	COG3177	Filamentation induced by cAMP protein fic
LZE81_01075	COG0596	Alpha beta hydrolase
LZE81_01085	COG0727	PFAM Uncharacterised protein family (UPF0153)
LZE81_01090	COG0318	PFAM AMP-dependent synthetase and ligase
LZE81_01105	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LZE81_01115	COG1181	Belongs to the D-alanine--D-alanine ligase family
LZE81_01130	COG4232	protein-disulfide reductase activity
LZE81_01135	COG0564	pseudouridine synthase activity
LZE81_01155	COG0339	signal peptide processing
LZE81_01175	COG0583	DNA-binding transcription factor activity
LZE81_01180	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
LZE81_01185	COG2224	Isocitrate lyase
LZE81_01220	COG0659	secondary active sulfate transmembrane transporter activity
LZE81_01250	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LZE81_01255	COG2130	NADP-dependent
LZE81_01270	COG1187	pseudouridine synthase activity
LZE81_01285	COG1643	Atp-dependent helicase
LZE81_01290	COG0084	hydrolase, TatD family'
LZE81_01330	COG0842	Transport permease protein
LZE81_01335	COG1131	(ABC) transporter
LZE81_01340	COG0633	Ferredoxin
LZE81_01340	COG0543	2 iron, 2 sulfur cluster binding
LZE81_01350	COG1476	TRANSCRIPTIONal
LZE81_01360	COG4555	ABC transporter
LZE81_01380	COG0625	glutathione transferase activity
LZE81_01425	COG0530	calcium, potassium:sodium antiporter activity
LZE81_01430	COG1320	monovalent cation:proton antiporter activity
LZE81_01435	COG2212	antiporter activity
LZE81_01440	COG1863	multisubunit Na H antiporter MnhE subunit
LZE81_01445	COG0651	ATP synthesis coupled electron transport
LZE81_01450	COG1006	Multisubunit Na H antiporter MnhC subunit
LZE81_01455	COG2111	Na H antiporter
LZE81_01455	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LZE81_01460	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LZE81_01475	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
LZE81_01490	COG1597	lipid kinase activity
LZE81_01520	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LZE81_01525	COG0134	indole-3-glycerol-phosphate synthase activity
LZE81_01535	COG0730	response to heat
LZE81_01540	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LZE81_01545	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
LZE81_01560	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
LZE81_01585	COG1051	belongs to the nudix hydrolase family
LZE81_01590	COG2906	2 iron, 2 sulfur cluster binding
LZE81_01635	COG2816	NAD+ diphosphatase activity
LZE81_01675	COG2814	Major facilitator Superfamily
LZE81_01680	COG1289	transmembrane transporter activity
LZE81_01685	COG0151	Belongs to the GarS family
LZE81_01690	COG0138	bifunctional purine biosynthesis protein purh
LZE81_01695	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LZE81_01720	COG4589	Belongs to the CDS family
LZE81_01725	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
LZE81_01745	COG2264	protein methyltransferase activity
LZE81_01760	COG0439	Biotin carboxylase
LZE81_01765	COG0511	ligase activity, forming carbon-carbon bonds
LZE81_01770	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
LZE81_01780	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LZE81_01790	COG1324	tolerance protein
LZE81_01805	COG0459	protein refolding
LZE81_01810	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LZE81_01835	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
LZE81_01855	COG0584	glycerophosphoryl diester phosphodiesterase
LZE81_01880	COG2353	YceI-like domain
LZE81_01895	COG0840	transmembrane signaling receptor activity
LZE81_01985	COG2267	carboxylic ester hydrolase activity
LZE81_02000	COG0583	DNA-binding transcription factor activity
LZE81_02010	COG0697	spore germination
LZE81_02015	COG1113	amino acid transport
LZE81_02020	COG0598	Magnesium transport protein CorA
LZE81_02030	COG2207	Transcriptional regulator
LZE81_02045	COG0741	lytic transglycosylase activity
LZE81_02060	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
LZE81_02060	COG5297	Belongs to the glycosyl hydrolase family 6
LZE81_02070	COG0531	amino acid
LZE81_02090	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
LZE81_02095	COG3275	phosphorelay sensor kinase activity
LZE81_02120	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LZE81_02125	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LZE81_02135	COG2076	Multidrug Resistance protein
LZE81_02145	COG4106	trans-aconitate 2-methyltransferase activity
LZE81_02180	COG5001	Diguanylate cyclase
LZE81_02185	COG2146	nitrite reductase [NAD(P)H] activity
LZE81_02210	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LZE81_02215	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LZE81_02225	COG0667	Aldo Keto reductase
LZE81_02250	COG3384	dioxygenase
LZE81_02260	COG1573	uracil-dna glycosylase
LZE81_02265	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
LZE81_02275	COG0025	NhaP-type Na H and K H
LZE81_02280	COG1131	(ABC) transporter
LZE81_02285	COG0842	Transport permease protein
LZE81_02350	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LZE81_02375	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LZE81_02375	COG2205	protein histidine kinase activity
LZE81_02400	COG1187	pseudouridine synthase activity
LZE81_02410	COG1666	GTP binding
LZE81_02415	COG0697	spore germination
LZE81_02420	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LZE81_02455	COG0508	dehydrogenase complex catalyzes the overall conversion of
LZE81_02460	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LZE81_02475	COG0356	it plays a direct role in the translocation of protons across the membrane
LZE81_02485	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LZE81_02495	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LZE81_02510	COG0355	proton-transporting ATP synthase activity, rotational mechanism
LZE81_02525	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LZE81_02560	COG1136	(ABC) transporter
LZE81_02560	COG0577	efflux transmembrane transporter activity
LZE81_02565	COG1136	(ABC) transporter
LZE81_02565	COG0577	efflux transmembrane transporter activity
LZE81_02570	COG1136	(ABC) transporter
LZE81_02580	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LZE81_02595	COG2132	Multicopper oxidase
LZE81_02610	COG2217	Heavy metal translocating P-type atpase
LZE81_02620	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LZE81_02625	COG0339	signal peptide processing
LZE81_02650	COG0546	phosphoglycolate phosphatase activity
LZE81_02660	COG4206	TonB-dependent receptor
LZE81_02670	COG1956	GAF domain-containing protein
LZE81_02675	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
LZE81_02685	COG0720	synthase
LZE81_02700	COG0625	glutathione transferase activity
LZE81_02730	COG0626	cystathionine gamma-synthase activity
LZE81_02745	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LZE81_02750	COG1216	Glycosyl transferase, family 2
LZE81_02750	COG0438	transferase activity, transferring glycosyl groups
LZE81_02755	COG0438	transferase activity, transferring glycosyl groups
LZE81_02755	COG1216	Glycosyl transferase, family 2
LZE81_02790	COG0493	'glutamate synthase
LZE81_02805	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LZE81_02810	COG0300	oxidoreductase activity
LZE81_02815	COG0277	FAD linked oxidase domain protein
LZE81_02820	COG0546	phosphoglycolate phosphatase activity
LZE81_02820	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
LZE81_02835	COG2086	electron transfer activity
LZE81_02860	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
LZE81_02860	COG0662	Cupin 2, conserved barrel domain protein
LZE81_02865	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LZE81_02870	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LZE81_02900	COG3218	ABC-type transport auxiliary lipoprotein component
LZE81_02900	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
LZE81_02905	COG1127	ABC transporter
LZE81_02910	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LZE81_02925	COG0442	prolyl-tRNA aminoacylation
LZE81_02935	COG1183	phosphatidylcholine synthase activity
LZE81_02970	COG2927	DNA polymerase III (CHI subunit)
LZE81_02975	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LZE81_03000	COG4974	Belongs to the 'phage' integrase family
LZE81_03005	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LZE81_03010	COG0047	phosphoribosylformylglycinamidine synthase activity
LZE81_03010	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LZE81_03015	COG0840	transmembrane signaling receptor activity
LZE81_03025	COG5295	Hep Hag repeat protein
LZE81_03030	COG1404	Belongs to the peptidase S8 family
LZE81_03035	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LZE81_03040	COG1459	type II secretion system
LZE81_03045	COG2165	general secretion pathway protein
LZE81_03050	COG4970	Tfp pilus assembly protein FimT
LZE81_03055	COG2165	general secretion pathway protein
LZE81_03060	COG4795	General secretion pathway protein
LZE81_03065	COG3156	type II secretion system protein K
LZE81_03070	COG3166	PFAM Fimbrial assembly family protein
LZE81_03085	COG1450	Type ii and iii secretion system protein
LZE81_03095	COG2188	Transcriptional regulator
LZE81_03145	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
LZE81_03155	COG1215	transferase activity, transferring glycosyl groups
LZE81_03175	COG1696	Membrane protein involved in D-alanine export
LZE81_03185	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LZE81_03195	COG1960	acyl-CoA dehydrogenase activity
LZE81_03205	COG0242	peptide deformylase activity
LZE81_03210	COG0488	(ABC) transporter
LZE81_03215	COG0477	Major facilitator Superfamily
LZE81_03245	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LZE81_03255	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LZE81_03255	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LZE81_03270	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
LZE81_03275	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LZE81_03280	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
LZE81_03305	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
LZE81_03310	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
LZE81_03320	COG2205	protein histidine kinase activity
LZE81_03325	COG0745	RESPONSE REGULATOR receiver
LZE81_03330	COG0277	FAD linked oxidase domain protein
LZE81_03340	COG0792	nuclease activity
LZE81_03375	COG2001	Belongs to the MraZ family
LZE81_03380	COG0275	rRNA processing
LZE81_03385	COG3116	cell division
LZE81_03400	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LZE81_03425	COG1181	Belongs to the D-alanine--D-alanine ligase family
LZE81_03430	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
LZE81_03440	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LZE81_03445	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
LZE81_03455	COG0739	heme binding
LZE81_03470	COG0494	nUDIX hydrolase
LZE81_03480	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
LZE81_03545	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LZE81_03565	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LZE81_03585	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LZE81_03590	COG0667	Aldo Keto reductase
LZE81_03600	COG4771	TonB-dependent receptor
LZE81_03620	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
LZE81_03625	COG4181	ATPase activity
LZE81_03640	COG0642	Histidine kinase
LZE81_03650	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
LZE81_03655	COG0861	Integral membrane protein TerC family
LZE81_03660	COG1704	LemA family
LZE81_03690	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
LZE81_03695	COG2967	ApaG domain
LZE81_03700	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LZE81_03705	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
LZE81_03710	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LZE81_03715	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
LZE81_03725	COG2096	Adenosyltransferase
LZE81_03735	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LZE81_03740	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LZE81_03780	COG0697	spore germination
LZE81_03785	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LZE81_03815	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LZE81_03830	COG0583	DNA-binding transcription factor activity
LZE81_03835	COG3634	alkyl hydroperoxide reductase activity
LZE81_03905	COG0488	(ABC) transporter
LZE81_03955	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LZE81_03960	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
LZE81_03975	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
LZE81_03985	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LZE81_03995	COG0193	aminoacyl-tRNA hydrolase activity
LZE81_04000	COG0012	GTP binding
LZE81_04020	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LZE81_04030	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LZE81_04035	COG0250	Participates in transcription elongation, termination and antitermination
LZE81_04040	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LZE81_04055	COG0222	ribosome binding
LZE81_04065	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LZE81_04080	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LZE81_04085	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LZE81_04090	COG0051	transcription antitermination factor activity, RNA binding
LZE81_04100	COG0088	Forms part of the polypeptide exit tunnel
LZE81_04105	COG0089	rRNA binding
LZE81_04110	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LZE81_04135	COG0255	Belongs to the universal ribosomal protein uL29 family
LZE81_04140	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LZE81_04150	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
LZE81_04155	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LZE81_04160	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LZE81_04185	COG1841	ribosomal large subunit assembly
LZE81_04195	COG0201	protein transport
LZE81_04220	COG0203	ribosomal protein L17
LZE81_04225	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
LZE81_04235	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
LZE81_04250	COG1217	gtp-binding protein TYPA
LZE81_04255	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LZE81_04265	COG0039	L-malate dehydrogenase activity
LZE81_04290	COG0625	glutathione transferase activity
LZE81_04335	COG1902	pentaerythritol trinitrate reductase activity
LZE81_04335	COG0446	pyridine nucleotide-disulphide oxidoreductase
LZE81_04345	COG0667	Aldo Keto reductase
LZE81_04365	COG2885	chlorophyll binding
LZE81_04380	COG0156	8-amino-7-oxononanoate synthase activity
LZE81_04385	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
LZE81_04390	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
LZE81_04395	COG4208	sulfate ABC transporter
LZE81_04400	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
LZE81_04420	COG0588	phosphoglycerate mutase activity
LZE81_04425	COG0285	dihydrofolate synthase activity
LZE81_04445	COG2833	Protein of unknown function (DUF455)
LZE81_04460	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LZE81_04470	COG0438	transferase activity, transferring glycosyl groups
LZE81_04475	COG0248	Ppx GppA phosphatase
LZE81_04480	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
LZE81_04495	COG4783	chaperone-mediated protein folding
LZE81_04510	COG0473	3-isopropylmalate dehydrogenase activity
LZE81_04550	COG0544	peptidyl-prolyl cis-trans isomerase activity
LZE81_04560	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LZE81_04595	COG3942	CHAP domain
LZE81_04595	COG1388	LysM domain
LZE81_04600	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LZE81_04610	COG0328	RNA-DNA hybrid ribonuclease activity
LZE81_04615	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LZE81_04620	COG0631	protein serine/threonine phosphatase activity
LZE81_04640	COG0859	PFAM glycosyl transferase family 9
LZE81_04650	COG1234	tRNA 3'-trailer cleavage
LZE81_04655	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
LZE81_04665	COG0315	cyclic pyranopterin monophosphate synthase activity
LZE81_04670	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
LZE81_04675	COG0314	molybdopterin synthase activity
LZE81_04790	COG0537	adenosine 5'-monophosphoramidase activity
LZE81_04810	COG0714	Associated with various cellular activities
LZE81_04835	COG1399	metal-binding, possibly nucleic acid-binding protein
LZE81_04845	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LZE81_04850	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
LZE81_04855	COG1028	Short-chain dehydrogenase reductase Sdr
LZE81_04860	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LZE81_04870	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LZE81_04875	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LZE81_04880	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LZE81_04900	COG4115	mRNA cleavage
LZE81_04905	COG2161	toxin-antitoxin pair type II binding
LZE81_04925	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
LZE81_04950	COG0372	Belongs to the citrate synthase family
LZE81_04970	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
LZE81_05020	COG2373	Large extracellular alpha-helical protein
LZE81_05040	COG4953	penicillin-binding protein 1C
LZE81_05050	COG0678	peroxiredoxin activity
LZE81_05070	COG0604	alcohol dehydrogenase
LZE81_05075	COG0330	HflC and HflK could
LZE81_05080	COG0330	HflC and HflK could
LZE81_05090	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LZE81_05215	COG3459	Glycosyltransferase 36 associated
LZE81_05225	COG1063	alcohol dehydrogenase
LZE81_05250	COG0753	catalase activity
LZE81_05260	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LZE81_05260	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LZE81_05285	COG2814	Major facilitator Superfamily
LZE81_05335	COG2194	sulfuric ester hydrolase activity
LZE81_05345	COG0745	RESPONSE REGULATOR receiver
LZE81_05350	COG2205	protein histidine kinase activity
LZE81_05360	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
LZE81_05365	COG2894	cell division
LZE81_05370	COG0850	regulation of cytokinetic process
LZE81_05380	COG4585	Histidine kinase
LZE81_05400	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
LZE81_05410	COG1216	Glycosyl transferase, family 2
LZE81_05415	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LZE81_05425	COG1199	ATP-dependent helicase activity
LZE81_05450	COG0189	ligase activity
LZE81_05465	COG0835	chemotaxis
LZE81_05470	COG0840	transmembrane signaling receptor activity
LZE81_05475	COG0643	Histidine kinase
LZE81_05475	COG0784	Response regulator, receiver
LZE81_05475	COG2198	Histidine kinase
LZE81_05480	COG2201	protein-glutamate methylesterase activity
LZE81_05510	COG1446	asparaginase
LZE81_05515	COG3142	Participates in the control of copper homeostasis
LZE81_05555	COG0217	transcriptional regulatory protein
LZE81_05565	COG0632	four-way junction helicase activity
LZE81_05570	COG3158	transport of potassium into the cell
LZE81_05575	COG2255	four-way junction helicase activity
LZE81_05580	COG0824	Thioesterase
LZE81_05590	COG0848	biopolymer transport protein
LZE81_05605	COG2885	chlorophyll binding
LZE81_05615	COG0602	queuosine metabolic process
LZE81_05620	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
LZE81_05640	COG0514	ATP-dependent DNA helicase (RecQ)
LZE81_05645	COG0783	Belongs to the Dps family
LZE81_05650	COG1643	Atp-dependent helicase
LZE81_05695	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LZE81_05775	COG1946	Acyl-CoA thioesterase
LZE81_05780	COG1024	Enoyl-CoA hydratase
LZE81_05790	COG0824	Thioesterase
LZE81_05795	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LZE81_05800	COG0261	This protein binds to 23S rRNA in the presence of protein L20
LZE81_05805	COG0211	Belongs to the bacterial ribosomal protein bL27 family
LZE81_05810	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LZE81_05820	COG0728	peptidoglycan biosynthetic process
LZE81_05845	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
LZE81_05880	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LZE81_05885	COG1845	cytochrome c oxidase, subunit III
LZE81_05890	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
LZE81_05900	COG0156	8-amino-7-oxononanoate synthase activity
LZE81_05955	COG0745	RESPONSE REGULATOR receiver
LZE81_05985	COG4794	Type iii secretion
LZE81_06010	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LZE81_06055	COG2207	Transcriptional regulator
LZE81_06085	COG0129	dihydroxy-acid dehydratase activity
LZE81_06105	COG1012	belongs to the aldehyde dehydrogenase family
LZE81_06110	COG1879	ABC-type sugar transport system periplasmic component
LZE81_06115	COG1129	ABC transporter
LZE81_06120	COG1172	Belongs to the binding-protein-dependent transport system permease family
LZE81_06125	COG1172	Belongs to the binding-protein-dependent transport system permease family
LZE81_06135	COG1082	Xylose isomerase domain protein TIM barrel
LZE81_06140	COG0625	glutathione transferase activity
LZE81_06150	COG0475	glutathione-regulated potassium exporter activity
LZE81_06175	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LZE81_06180	COG2070	2-Nitropropane dioxygenase
LZE81_06195	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LZE81_06200	COG0336	Belongs to the RNA methyltransferase TrmD family
LZE81_06205	COG0335	large ribosomal subunit rRNA binding
LZE81_06210	COG0534	Mate efflux family protein
LZE81_06220	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
LZE81_06250	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LZE81_06265	COG2855	membrane
LZE81_06300	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LZE81_06305	COG0481	GTPase activity
LZE81_06310	COG0681	Belongs to the peptidase S26 family
LZE81_06325	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LZE81_06330	COG1381	Involved in DNA repair and RecF pathway recombination
LZE81_06335	COG0745	RESPONSE REGULATOR receiver
LZE81_06345	COG2954	triphosphatase activity
LZE81_06355	COG1472	Belongs to the glycosyl hydrolase 3 family
LZE81_06360	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
LZE81_06365	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
LZE81_06370	COG1278	Cold shock
LZE81_06375	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LZE81_06385	COG1201	RNA secondary structure unwinding
LZE81_06390	COG1793	dna ligase
LZE81_06390	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
LZE81_06395	COG1793	dna ligase
LZE81_06395	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
LZE81_06425	COG0443	Heat shock 70 kDa protein
LZE81_06435	COG0183	Belongs to the thiolase family
LZE81_06465	COG1703	isobutyryl-CoA mutase activity
LZE81_06465	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
LZE81_06465	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
LZE81_06530	COG3250	beta-galactosidase activity
LZE81_06535	COG2186	Transcriptional regulator
LZE81_06545	COG0784	Response regulator, receiver
LZE81_06545	COG2198	Histidine kinase
LZE81_06545	COG2205	protein histidine kinase activity
LZE81_06565	COG1451	nucleotide metabolic process
LZE81_06575	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
LZE81_06610	COG1077	Cell shape determining protein MreB Mrl
LZE81_06615	COG1047	Peptidyl-prolyl cis-trans
LZE81_06620	COG2824	Alkylphosphonate utilization operon protein PhnA
LZE81_06625	COG1902	pentaerythritol trinitrate reductase activity
LZE81_06660	COG0392	lysyltransferase activity
LZE81_06660	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LZE81_06670	COG0251	oxidation-reduction process
LZE81_06690	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LZE81_06715	COG1595	DNA-templated transcription, initiation
LZE81_06730	COG2878	Part of a membrane complex involved in electron transport
LZE81_06750	COG0346	lactoylglutathione lyase activity
LZE81_06760	COG0833	amino acid
LZE81_06765	COG2040	homocysteine
LZE81_06775	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
LZE81_06790	COG3118	belongs to the thioredoxin family
LZE81_06800	COG0495	leucyl-tRNA aminoacylation
LZE81_06815	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LZE81_06830	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
LZE81_06845	COG2968	Membrane
LZE81_06865	COG0312	modulator of DNA gyrase
LZE81_06875	COG0312	modulator of DNA gyrase
LZE81_06970	COG0631	protein serine/threonine phosphatase activity
LZE81_06975	COG0515	serine threonine protein kinase
LZE81_06975	COG2815	serine threonine protein kinase
LZE81_07000	COG1858	cytochrome C peroxidase
LZE81_07010	COG0142	geranyltranstransferase activity
LZE81_07015	COG1722	exodeoxyribonuclease VII activity
LZE81_07020	COG0037	tRNA processing
LZE81_07030	COG1785	Belongs to the alkaline phosphatase family
LZE81_07035	COG1301	dicarboxylic acid transport
LZE81_07045	COG1607	acyl-coa hydrolase
LZE81_07060	COG0791	NLP P60 protein
LZE81_07065	COG0791	NLP P60 protein
LZE81_07070	COG1047	Peptidyl-prolyl cis-trans
LZE81_07075	COG2311	Membrane
LZE81_07080	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LZE81_07100	COG0697	spore germination
LZE81_07140	COG3590	peptidase
LZE81_07155	COG0457	Tetratricopeptide repeat
LZE81_07160	COG4771	TonB-dependent receptor
LZE81_07170	COG4771	TonB-dependent receptor
LZE81_07180	COG0489	protein tyrosine kinase activity
LZE81_07185	COG0717	Belongs to the dCTP deaminase family
LZE81_07190	COG1714	RDD family
LZE81_07210	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LZE81_07225	COG0494	nUDIX hydrolase
LZE81_07230	COG0433	COG0433 Predicted ATPase
LZE81_07235	COG0741	lytic transglycosylase activity
LZE81_07240	COG0688	phosphatidylethanolamine metabolic process
LZE81_07250	COG2890	protein-(glutamine-N5) methyltransferase activity
LZE81_07315	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
LZE81_07345	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LZE81_07355	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LZE81_07360	COG0649	NAD binding
LZE81_07365	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
LZE81_07370	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
LZE81_07410	COG1007	ATP synthesis coupled electron transport
LZE81_07425	COG0195	Participates in both transcription termination and antitermination
LZE81_07440	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LZE81_07450	COG1185	polyribonucleotide nucleotidyltransferase activity
LZE81_07455	COG3300	MHYT domain
LZE81_07455	COG5001	Diguanylate cyclase
LZE81_07470	COG0840	transmembrane signaling receptor activity
LZE81_07475	COG0840	transmembrane signaling receptor activity
LZE81_07480	COG0835	chemotaxis
LZE81_07525	COG1194	a g-specific adenine glycosylase
LZE81_07530	COG0552	protein localization to endoplasmic reticulum
LZE81_07540	COG3938	Belongs to the proline racemase family
LZE81_07545	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LZE81_07560	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LZE81_07570	COG0006	proline dipeptidase activity
LZE81_07585	COG0531	amino acid
LZE81_07610	COG4206	TonB-dependent receptor
LZE81_07620	COG3507	Belongs to the glycosyl hydrolase 43 family
LZE81_07630	COG4771	TonB-dependent receptor
LZE81_07655	COG0742	ribosomal rna small subunit methyltransferase
LZE81_07670	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LZE81_07675	COG0405	Gamma-glutamyltransferase
LZE81_07680	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LZE81_07685	COG3291	Pkd domain containing protein
LZE81_07690	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LZE81_07700	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LZE81_07710	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
LZE81_07720	COG1862	Preprotein translocase
LZE81_07725	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LZE81_07750	COG2203	Gaf domain
LZE81_07750	COG3706	GGDEF domain
LZE81_07750	COG4251	negative regulation of phosphorylation
LZE81_07750	COG5001	Diguanylate cyclase
LZE81_07755	COG1509	lysine 2,3-aminomutase activity
LZE81_07765	COG3548	integral membrane protein
LZE81_07770	COG0402	S-adenosylhomocysteine deaminase activity
LZE81_07800	COG4677	pectinesterase activity
LZE81_07805	COG3547	Transposase (IS116 IS110 IS902 family)
LZE81_07840	COG2850	peptidyl-arginine hydroxylation
LZE81_07880	COG1131	(ABC) transporter
LZE81_07885	COG1725	Transcriptional regulator
LZE81_07895	COG0386	Belongs to the glutathione peroxidase family
LZE81_07910	COG2900	Belongs to the SlyX family
LZE81_07920	COG2755	lipolytic protein G-D-S-L family
LZE81_07920	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
LZE81_07930	COG0646	methionine synthase
LZE81_07930	COG1410	methionine synthase
LZE81_07935	COG0646	methionine synthase
LZE81_07935	COG1410	methionine synthase
LZE81_07945	COG1960	acyl-CoA dehydrogenase activity
LZE81_07950	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LZE81_07955	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LZE81_07965	COG2902	Dehydrogenase
LZE81_08015	COG2925	Exonuclease
LZE81_08025	COG3844	kynureninase activity
LZE81_08040	COG0288	reversible hydration of carbon dioxide
LZE81_08110	COG0316	Belongs to the HesB IscA family
LZE81_08145	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LZE81_08150	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LZE81_08155	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
LZE81_08165	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
LZE81_08200	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
LZE81_08215	COG1228	amidohydrolase
LZE81_08230	COG4221	oxidoreductase activity
LZE81_08270	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
LZE81_08275	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
LZE81_08280	COG1605	Chorismate mutase
LZE81_08280	COG0077	Prephenate dehydratase
LZE81_08305	COG0583	DNA-binding transcription factor activity
LZE81_08360	COG0577	efflux transmembrane transporter activity
LZE81_08360	COG1136	(ABC) transporter
LZE81_08390	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LZE81_08390	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LZE81_08395	COG1105	Belongs to the carbohydrate kinase PfkB family
LZE81_08400	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LZE81_08400	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
LZE81_08405	COG1609	Transcriptional regulator
LZE81_08415	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
LZE81_08420	COG0069	glutamate synthase activity
LZE81_08455	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LZE81_08470	COG1253	flavin adenine dinucleotide binding
LZE81_08480	COG0306	phosphate transporter
LZE81_08500	COG0504	CTP synthase activity
LZE81_08515	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
LZE81_08520	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
LZE81_08525	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
LZE81_08540	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
LZE81_08550	COG1238	metal cluster binding
LZE81_08565	COG1534	Rna-binding protein
LZE81_08570	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
LZE81_08575	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LZE81_08580	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LZE81_08585	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LZE81_08595	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LZE81_08600	COG1546	Belongs to the CinA family
LZE81_08605	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
LZE81_08610	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LZE81_08615	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LZE81_08620	COG2137	regulation of response to DNA damage stimulus
LZE81_08670	COG1294	oxidase, subunit
LZE81_08680	COG4988	ABC transporter
LZE81_08685	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
LZE81_08690	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LZE81_08740	COG4133	protoheme IX ABC transporter activity
LZE81_08745	COG0436	Aminotransferase
LZE81_08770	COG1187	pseudouridine synthase activity
LZE81_08775	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LZE81_08780	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
LZE81_08785	COG2350	Protein conserved in bacteria
LZE81_08820	COG0395	ABC-type sugar transport system, permease component
LZE81_08835	COG0129	dihydroxy-acid dehydratase activity
LZE81_08850	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LZE81_08855	COG3842	ATPase activity
LZE81_08860	COG0354	folic acid binding
LZE81_08870	COG2009	succinate dehydrogenase
LZE81_08875	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
LZE81_08890	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
LZE81_08900	COG4591	ABC-type transport system involved in lipoprotein release permease component
LZE81_08920	COG0811	peptide transport
LZE81_08930	COG1132	(ABC) transporter
LZE81_08935	COG1663	tetraacyldisaccharide 4'-kinase activity
LZE81_08945	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LZE81_08960	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LZE81_08995	COG3209	COG3209 Rhs family protein
LZE81_09150	COG3179	chitinase
LZE81_09290	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
LZE81_09295	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LZE81_09305	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LZE81_09330	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LZE81_09335	COG2258	MOSC domain
LZE81_09345	COG0505	Belongs to the CarA family
LZE81_09355	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
LZE81_09360	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LZE81_09370	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LZE81_09455	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
LZE81_09475	COG1024	Enoyl-CoA hydratase
LZE81_09485	COG1024	Enoyl-CoA hydratase
LZE81_09490	COG1024	Enoyl-CoA hydratase
LZE81_09515	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LZE81_09530	COG0346	lactoylglutathione lyase activity
LZE81_09540	COG1304	FMN binding
LZE81_09545	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LZE81_09550	COG1649	PFAM Uncharacterised BCR, COG1649
LZE81_09625	COG2183	response to ionizing radiation
LZE81_09630	COG0784	Response regulator, receiver
LZE81_09630	COG4191	Histidine kinase
LZE81_09640	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LZE81_09640	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
LZE81_09660	COG3243	poly(R)-hydroxyalkanoic acid synthase
LZE81_09670	COG1183	phosphatidylcholine synthase activity
LZE81_09675	COG1028	Short-chain dehydrogenase reductase Sdr
LZE81_09690	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
LZE81_09700	COG0668	transmembrane transport
LZE81_09705	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
LZE81_09720	COG1914	H( )-stimulated, divalent metal cation uptake system
LZE81_09730	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
LZE81_09735	COG1501	Belongs to the glycosyl hydrolase 31 family
LZE81_09785	COG4691	Plasmid stability protein
LZE81_09790	COG1487	ribonuclease activity
LZE81_09865	COG0519	Catalyzes the synthesis of GMP from XMP
LZE81_09865	COG0519	Catalyzes the synthesis of GMP from XMP
LZE81_09865	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LZE81_09865	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LZE81_09895	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LZE81_09895	COG0519	Catalyzes the synthesis of GMP from XMP
LZE81_09905	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LZE81_09925	COG0475	glutathione-regulated potassium exporter activity
LZE81_09925	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LZE81_09930	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LZE81_09940	COG0746	molybdenum cofactor guanylyltransferase activity
LZE81_09950	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LZE81_09960	COG1426	Protein conserved in bacteria
LZE81_09970	COG0820	rRNA (adenine-C2-)-methyltransferase activity
LZE81_09985	COG1250	3-hydroxyacyl-CoA dehydrogenase
LZE81_09985	COG1024	Enoyl-CoA hydratase
LZE81_09990	COG0183	Belongs to the thiolase family
LZE81_09995	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LZE81_10005	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LZE81_10010	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
LZE81_10020	COG0776	regulation of translation
LZE81_10025	COG0539	negative regulation of cytoplasmic translation
LZE81_10030	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
LZE81_10035	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LZE81_10045	COG2957	Belongs to the agmatine deiminase family
LZE81_10050	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LZE81_10070	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LZE81_10090	COG0316	Belongs to the HesB IscA family
LZE81_10090	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
LZE81_10105	COG0428	transporter
LZE81_10120	COG1530	ribonuclease E activity
LZE81_10150	COG2801	Transposase and inactivated derivatives
LZE81_10170	COG0512	Glutamine amidotransferase of anthranilate synthase
LZE81_10205	COG1022	Amp-dependent synthetase and ligase
LZE81_10210	COG2801	Transposase and inactivated derivatives
LZE81_10240	COG1132	(ABC) transporter
LZE81_10260	COG0438	transferase activity, transferring glycosyl groups
LZE81_10265	COG0438	transferase activity, transferring glycosyl groups
LZE81_10285	COG4106	trans-aconitate 2-methyltransferase activity
LZE81_10305	COG2244	polysaccharide biosynthetic process
LZE81_10335	COG3038	cytochrome b561
LZE81_10355	COG1595	DNA-templated transcription, initiation
LZE81_10410	COG0038	chloride channel
LZE81_10415	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LZE81_10435	COG1674	ftsk spoiiie
LZE81_10440	COG0492	ferredoxin-NADP+ reductase activity
LZE81_10460	COG0542	response to heat
LZE81_10480	COG0482	sulfurtransferase activity
LZE81_10485	COG2915	High frequency lysogenization protein hflD homolog
LZE81_10550	COG0784	Response regulator, receiver
LZE81_10550	COG0835	chemotaxis
LZE81_10560	COG1558	bacterial-type flagellum-dependent cell motility
LZE81_10570	COG1749	Flagellar hook protein flgE
LZE81_10585	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
LZE81_10600	COG4786	Flagellar basal body rod
LZE81_10600	COG1256	bacterial-type flagellum assembly
LZE81_10600	COG1256	bacterial-type flagellum assembly
LZE81_10600	COG4786	Flagellar basal body rod
LZE81_10605	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LZE81_10610	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LZE81_10615	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
LZE81_10635	COG2197	response regulator
LZE81_10640	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
LZE81_10645	COG2201	protein-glutamate methylesterase activity
LZE81_10665	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LZE81_10670	COG1028	Short-chain dehydrogenase reductase Sdr
LZE81_10675	COG1028	Short-chain dehydrogenase reductase Sdr
LZE81_10720	COG1677	Flagellar hook-basal body complex protein FliE
LZE81_10770	COG3190	flagellar
LZE81_10780	COG1987	bacterial-type flagellum assembly
LZE81_10785	COG1684	flagellar biosynthetic protein fliR
LZE81_10830	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
LZE81_10835	COG0643	Histidine kinase
LZE81_10835	COG2198	Histidine kinase
LZE81_10835	COG0784	Response regulator, receiver
LZE81_10840	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
LZE81_10850	COG1192	Involved in chromosome partitioning
LZE81_10855	COG0835	chemotaxis
LZE81_10865	COG0745	RESPONSE REGULATOR receiver
LZE81_10880	COG0840	transmembrane signaling receptor activity
LZE81_10885	COG0840	transmembrane signaling receptor activity
LZE81_10895	COG0840	transmembrane signaling receptor activity
LZE81_10900	COG0840	transmembrane signaling receptor activity
LZE81_10910	COG0840	transmembrane signaling receptor activity
LZE81_10920	COG0840	transmembrane signaling receptor activity
LZE81_10925	COG0840	transmembrane signaling receptor activity
LZE81_10930	COG0840	transmembrane signaling receptor activity
LZE81_10940	COG0840	transmembrane signaling receptor activity
LZE81_10950	COG0835	chemotaxis
LZE81_10960	COG0840	transmembrane signaling receptor activity
LZE81_10970	COG0840	transmembrane signaling receptor activity
LZE81_10995	COG3706	GGDEF domain
LZE81_11025	COG0318	PFAM AMP-dependent synthetase and ligase
LZE81_11030	COG1024	Enoyl-CoA hydratase
LZE81_11035	COG0784	Response regulator, receiver
LZE81_11035	COG2198	Histidine kinase
LZE81_11035	COG2205	protein histidine kinase activity
LZE81_11070	COG0800	Aldolase
LZE81_11085	COG3734	2-keto-3-deoxy-galactonokinase
LZE81_11090	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
LZE81_11100	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LZE81_11110	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LZE81_11115	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
LZE81_11130	COG0352	thiamine-phosphate diphosphorylase activity
LZE81_11130	COG0351	phosphomethylpyrimidine kinase
LZE81_11150	COG0583	DNA-binding transcription factor activity
LZE81_11155	COG1741	Belongs to the pirin family
LZE81_11210	COG1024	Enoyl-CoA hydratase
LZE81_11225	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LZE81_11245	COG0277	FAD linked oxidase domain protein
LZE81_11250	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LZE81_11265	COG0531	amino acid
LZE81_11270	COG0531	amino acid
LZE81_11275	COG0235	Class ii aldolase
LZE81_11280	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
LZE81_11285	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
LZE81_11300	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
LZE81_11300	COG0140	phosphoribosyl-ATP diphosphatase activity
LZE81_11315	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LZE81_11325	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LZE81_11330	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LZE81_11335	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
LZE81_11345	COG0124	histidyl-tRNA synthetase
LZE81_11350	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LZE81_11360	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
LZE81_11370	COG2951	lytic endotransglycosylase activity
LZE81_11380	COG0460	homoserine dehydrogenase
LZE81_11380	COG0527	aspartate kinase activity
LZE81_11395	COG1012	belongs to the aldehyde dehydrogenase family
LZE81_11410	COG0167	dihydroorotate dehydrogenase activity
LZE81_11415	COG0812	UDP-N-acetylmuramate dehydrogenase activity
LZE81_11440	COG0671	phosphoesterase, PA-phosphatase related
LZE81_11455	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
LZE81_11530	COG0166	Belongs to the GPI family
LZE81_11545	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
LZE81_11555	COG0617	tRNA 3'-terminal CCA addition
LZE81_11575	COG0860	N-Acetylmuramoyl-L-alanine amidase
LZE81_11580	COG0477	Major facilitator Superfamily
LZE81_11585	COG2115	Belongs to the xylose isomerase family
LZE81_11590	COG1070	Carbohydrate kinase
LZE81_11600	COG1501	Belongs to the glycosyl hydrolase 31 family
LZE81_11625	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LZE81_11645	COG0165	Argininosuccinate lyase
LZE81_11650	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
LZE81_11660	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
LZE81_11665	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LZE81_11670	COG0137	argininosuccinate synthase activity
LZE81_11675	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LZE81_11690	COG2166	iron-sulfur cluster assembly
LZE81_11720	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LZE81_11755	COG1132	(ABC) transporter
LZE81_11765	COG1605	Chorismate mutase
LZE81_11765	COG0287	Prephenate dehydrogenase
LZE81_11770	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
LZE81_11775	COG0484	heat shock protein binding
LZE81_11780	COG0443	Heat shock 70 kDa protein
LZE81_11785	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LZE81_11790	COG1420	regulation of RNA biosynthetic process
LZE81_11795	COG0497	DNA recombination
LZE81_11800	COG0735	belongs to the Fur family
LZE81_11805	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LZE81_11815	COG2867	negative regulation of translational initiation
LZE81_11820	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
LZE81_11825	COG1404	Belongs to the peptidase S8 family
LZE81_11865	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LZE81_11880	COG0583	DNA-binding transcription factor activity
LZE81_11895	COG0415	Belongs to the DNA photolyase family
LZE81_11900	COG0305	Participates in initiation and elongation during chromosome replication
LZE81_11910	COG1960	acyl-CoA dehydrogenase activity
LZE81_11925	COG0084	hydrolase, TatD family'
LZE81_11930	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
LZE81_11980	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LZE81_12005	COG0386	Belongs to the glutathione peroxidase family
LZE81_12020	COG1846	Transcriptional regulator
LZE81_12060	COG1472	Belongs to the glycosyl hydrolase 3 family
LZE81_12070	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LZE81_12075	COG4290	ribonuclease
LZE81_12090	COG0488	(ABC) transporter
LZE81_12095	COG0513	Belongs to the DEAD box helicase family
LZE81_12120	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
LZE81_12125	COG0657	acetylesterase activity
LZE81_12130	COG0625	glutathione transferase activity
LZE81_12140	COG0564	pseudouridine synthase activity
LZE81_12145	COG4681	YaeQ
LZE81_12150	COG2081	HI0933 family
LZE81_12170	COG1028	Short-chain dehydrogenase reductase Sdr
LZE81_12190	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LZE81_12195	COG0860	N-Acetylmuramoyl-L-alanine amidase
LZE81_12200	COG0802	atpase or kinase
LZE81_12205	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LZE81_12205	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LZE81_12210	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LZE81_12215	COG1570	exodeoxyribonuclease VII activity
LZE81_12245	COG1960	acyl-CoA dehydrogenase activity
LZE81_12255	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LZE81_12275	COG0438	transferase activity, transferring glycosyl groups
LZE81_12285	COG0438	transferase activity, transferring glycosyl groups
LZE81_12290	COG0438	transferase activity, transferring glycosyl groups
LZE81_12340	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LZE81_12345	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LZE81_12355	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LZE81_12385	COG0556	nucleotide-excision repair
LZE81_12430	COG3275	phosphorelay sensor kinase activity
LZE81_12435	COG1611	Belongs to the LOG family
LZE81_12445	COG2095	MarC family integral membrane protein
LZE81_12450	COG1028	Short-chain dehydrogenase reductase Sdr
LZE81_12455	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
LZE81_12495	COG2969	positive regulation of protein catabolic process
LZE81_12500	COG0625	glutathione transferase activity
LZE81_12505	COG2857	Cytochrome c1
LZE81_12515	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
LZE81_12520	COG0723	plastoquinol--plastocyanin reductase activity
LZE81_12525	COG0741	lytic transglycosylase activity
LZE81_12540	COG1702	phosphate starvation-inducible protein PhoH
LZE81_12555	COG4535	Mg2 and Co2 transporter CorC
LZE81_12570	COG1012	belongs to the aldehyde dehydrogenase family
LZE81_12575	COG1177	transmembrane transport
LZE81_12580	COG1176	ABC-type spermidine putrescine transport system, permease component I
LZE81_12585	COG3842	ATPase activity
LZE81_12610	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
LZE81_12620	COG0174	glutamine synthetase
LZE81_12625	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
LZE81_12630	COG0174	glutamine synthetase
LZE81_12635	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LZE81_12645	COG0477	Major facilitator Superfamily
LZE81_12660	COG0243	molybdopterin cofactor binding
LZE81_12670	COG2223	nitrite transmembrane transporter activity
LZE81_12690	COG1012	belongs to the aldehyde dehydrogenase family
LZE81_12695	COG1396	sequence-specific DNA binding
LZE81_12695	COG1917	Cupin 2, conserved barrel domain protein
LZE81_12700	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LZE81_12705	COG0686	Belongs to the AlaDH PNT family
LZE81_12725	COG2733	membrane
LZE81_12730	COG5002	protein histidine kinase activity
LZE81_12730	COG0784	Response regulator, receiver
LZE81_12730	COG2205	protein histidine kinase activity
LZE81_12785	COG1024	Enoyl-CoA hydratase
LZE81_12795	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LZE81_12800	COG0659	secondary active sulfate transmembrane transporter activity
LZE81_12820	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LZE81_12825	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LZE81_12835	COG0581	inorganic phosphate transmembrane transporter activity
LZE81_12845	COG0704	Plays a role in the regulation of phosphate uptake
LZE81_12865	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LZE81_12875	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LZE81_12885	COG0557	exoribonuclease II activity
LZE81_12920	COG2814	Major facilitator Superfamily
LZE81_12925	COG1566	PFAM secretion protein HlyD family protein
LZE81_12960	COG0367	asparagine synthase
LZE81_12970	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LZE81_12975	COG1393	Belongs to the ArsC family
LZE81_12990	COG0024	Methionine aminopeptidase
LZE81_13030	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LZE81_13040	COG0528	UMP kinase activity
LZE81_13050	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LZE81_13055	COG0575	Belongs to the CDS family
LZE81_13060	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
LZE81_13065	COG0750	zinc metalloprotease
LZE81_13070	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LZE81_13075	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LZE81_13085	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LZE81_13090	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LZE81_13115	COG1981	membrane
LZE81_13155	COG0583	DNA-binding transcription factor activity
LZE81_13185	COG1132	(ABC) transporter
LZE81_13210	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LZE81_13235	COG1187	pseudouridine synthase activity
LZE81_13345	COG2080	2 iron, 2 sulfur cluster binding
LZE81_13350	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
LZE81_13355	COG1529	Aldehyde oxidase and xanthine dehydrogenase
LZE81_13390	COG0735	belongs to the Fur family
LZE81_13395	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LZE81_13420	COG4452	Inner membrane protein CreD
LZE81_13430	COG2205	protein histidine kinase activity
LZE81_13440	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
LZE81_13445	COG3878	Protein conserved in bacteria
LZE81_13470	COG0643	Histidine kinase
LZE81_13470	COG2198	Histidine kinase
LZE81_13475	COG0840	transmembrane signaling receptor activity
LZE81_13480	COG0840	transmembrane signaling receptor activity
LZE81_13485	COG0840	transmembrane signaling receptor activity
LZE81_13490	COG0835	chemotaxis
LZE81_13495	COG5001	Diguanylate cyclase
LZE81_13495	COG4251	negative regulation of phosphorylation
LZE81_13495	COG3706	GGDEF domain
LZE81_13495	COG2203	Gaf domain
LZE81_13530	COG2211	Major facilitator Superfamily
LZE81_13565	COG1966	Carbon starvation protein
LZE81_13570	COG2879	small protein
LZE81_13575	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LZE81_13595	COG0823	Involved in the tonB-independent uptake of proteins
LZE81_13595	COG1506	peptidase
LZE81_13600	COG1297	OPT oligopeptide transporter protein
LZE81_13605	COG3104	oligopeptide transport
LZE81_13620	COG3550	peptidyl-serine autophosphorylation
LZE81_13625	COG0629	single-stranded DNA binding
LZE81_13630	COG0142	geranyltranstransferase activity
LZE81_13655	COG0527	aspartate kinase activity
LZE81_13660	COG0384	phenazine biosynthesis protein PhzF
LZE81_13670	COG1764	response to oxidative stress
LZE81_13685	COG0739	heme binding
LZE81_13700	COG0693	protein deglycase activity
LZE81_13715	COG0719	Fe-S assembly protein
LZE81_13720	COG0396	ATPase activity
LZE81_13725	COG0719	Fe-S assembly protein
LZE81_13730	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LZE81_13740	COG2146	nitrite reductase [NAD(P)H] activity
LZE81_13745	COG4774	siderophore transport
LZE81_13770	COG1477	protein flavinylation
LZE81_13795	COG1555	photosystem II stabilization
LZE81_13810	COG3178	'Phosphotransferase
LZE81_13815	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LZE81_13825	COG0628	permease
LZE81_13850	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LZE81_13895	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
LZE81_13910	COG1137	ATPase activity
LZE81_13925	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LZE81_13935	COG1660	Displays ATPase and GTPase activities
LZE81_13945	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LZE81_13950	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LZE81_13955	COG2239	Acts as a magnesium transporter
LZE81_13975	COG1113	amino acid transport
LZE81_13985	COG0840	transmembrane signaling receptor activity
LZE81_14005	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LZE81_14020	COG0519	Catalyzes the synthesis of GMP from XMP
LZE81_14080	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LZE81_14095	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LZE81_14100	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LZE81_14110	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
LZE81_14115	COG2814	Major facilitator Superfamily
LZE81_14135	COG3038	cytochrome b561
LZE81_14150	COG1760	l-serine dehydratase
LZE81_14160	COG2267	carboxylic ester hydrolase activity
LZE81_14165	COG0460	homoserine dehydrogenase
LZE81_14165	COG0527	aspartate kinase activity
LZE81_14170	COG0626	cystathionine gamma-synthase activity
LZE81_14175	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LZE81_14185	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
LZE81_14190	COG1272	protein, Hemolysin III
LZE81_14195	COG2982	Protein involved in outer membrane biogenesis
LZE81_14200	COG0517	IMP dehydrogenase activity
LZE81_14205	COG0463	Glycosyl transferase, family 2
LZE81_14210	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LZE81_14215	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
LZE81_14225	COG4206	TonB-dependent receptor
LZE81_14245	COG1304	FMN binding
LZE81_14255	COG1657	PFAM Prenyltransferase squalene oxidase
LZE81_14260	COG0142	geranyltranstransferase activity
LZE81_14265	COG2124	cytochrome p450
LZE81_14270	COG1028	Short-chain dehydrogenase reductase Sdr
LZE81_14275	COG1141	Ferredoxin
LZE81_14280	COG2124	cytochrome p450
LZE81_14285	COG2124	cytochrome p450
LZE81_14315	COG0697	spore germination
LZE81_14350	COG0330	HflC and HflK could
LZE81_14360	COG1742	UPF0060 membrane protein
LZE81_14365	COG3956	TIGRFAM MazG family protein
LZE81_14370	COG1218	3'(2'),5'-bisphosphate nucleotidase
LZE81_14375	COG0494	nUDIX hydrolase
LZE81_14385	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LZE81_14395	COG0837	glucose binding
LZE81_14410	COG1388	LysM domain
LZE81_14410	COG3858	chitin binding
LZE81_14415	COG3525	Glycosyl hydrolase, family 20, catalytic domain
LZE81_14425	COG1472	Belongs to the glycosyl hydrolase 3 family
LZE81_14445	COG3537	Alpha-1,2-mannosidase
LZE81_14545	COG0521	Mo-molybdopterin cofactor biosynthetic process
LZE81_14565	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LZE81_14570	COG1295	ribonuclease BN
LZE81_14605	COG1404	Belongs to the peptidase S8 family
LZE81_14610	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LZE81_14650	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
LZE81_14670	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LZE81_14670	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LZE81_14730	COG4651	solute:proton antiporter activity
LZE81_14730	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LZE81_14745	COG4772	TonB-dependent receptor
LZE81_14755	COG4264	IucA IucC family
LZE81_14760	COG2814	Major facilitator Superfamily
LZE81_14765	COG4264	IucA IucC family
LZE81_14770	COG0019	diaminopimelate decarboxylase activity
LZE81_14795	COG0542	response to heat
LZE81_14825	COG0454	-acetyltransferase
LZE81_14850	COG3387	PFAM Glycoside hydrolase 15-related
LZE81_14875	COG0564	pseudouridine synthase activity
LZE81_14880	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LZE81_14890	COG1125	glycine betaine transport
LZE81_14895	COG1174	glycine betaine transport
LZE81_14910	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LZE81_14920	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LZE81_14920	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
LZE81_14980	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
LZE81_14995	COG0745	RESPONSE REGULATOR receiver
LZE81_15005	COG0189	ligase activity
LZE81_15015	COG3511	phospholipase C
LZE81_15035	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
LZE81_15050	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
LZE81_15060	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
LZE81_15065	COG0174	glutamine synthetase
LZE81_15090	COG2022	thiamine diphosphate biosynthetic process
LZE81_15100	COG0471	metal ion transport
LZE81_15100	COG3273	potassium ion transport
LZE81_15115	COG0179	Fumarylacetoacetate (FAA) hydrolase
LZE81_15130	COG1609	Transcriptional regulator
LZE81_15145	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LZE81_15175	COG0840	transmembrane signaling receptor activity
LZE81_15180	COG2895	sulfate adenylyltransferase (ATP) activity
LZE81_15180	COG0529	Catalyzes the synthesis of activated sulfate
LZE81_15190	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LZE81_15195	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LZE81_15200	COG0175	sulfate reduction
LZE81_15230	COG1393	Belongs to the ArsC family
LZE81_15235	COG2205	protein histidine kinase activity
LZE81_15235	COG0784	Response regulator, receiver
LZE81_15235	COG2198	Histidine kinase
LZE81_15250	COG1648	precorrin-2 dehydrogenase activity
LZE81_15250	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LZE81_15265	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
LZE81_15300	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
LZE81_15305	COG3588	fructose-bisphosphate aldolase
LZE81_15310	COG0469	pyruvate kinase activity
LZE81_15360	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LZE81_15365	COG3047	cAMP biosynthetic process
LZE81_15390	COG0640	Transcriptional regulator
LZE81_15400	COG0725	ABC transporter, periplasmic molybdate-binding protein
LZE81_15405	COG4149	molybdate abc transporter
LZE81_15410	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
LZE81_15445	COG1376	ErfK ybiS ycfS ynhG family protein
LZE81_15450	COG0739	heme binding
LZE81_15480	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LZE81_15485	COG1301	dicarboxylic acid transport
LZE81_15515	COG0714	Associated with various cellular activities
LZE81_15545	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
LZE81_15560	COG0372	Belongs to the citrate synthase family
LZE81_15565	COG0254	rRNA binding
LZE81_15575	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LZE81_15585	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LZE81_15590	COG1758	RNA polymerase activity
LZE81_15595	COG0194	GDP metabolic process
LZE81_15600	COG1561	YicC-like family, N-terminal region
LZE81_15605	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
LZE81_15610	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LZE81_15615	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LZE81_15635	COG0006	proline dipeptidase activity
LZE81_15640	COG0006	proline dipeptidase activity
LZE81_15645	COG3079	Belongs to the UPF0149 family
LZE81_15670	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LZE81_15680	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
LZE81_15695	COG1773	rubredoxin
LZE81_15720	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
LZE81_15740	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LZE81_15750	COG1940	carbohydrate kinase activity
LZE81_15765	COG0671	phosphoesterase, PA-phosphatase related
LZE81_15775	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LZE81_15800	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
LZE81_15810	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
LZE81_15835	COG0840	transmembrane signaling receptor activity
LZE81_15840	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
LZE81_15860	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LZE81_15880	COG0066	3-isopropylmalate dehydratase activity
LZE81_15885	COG0473	3-isopropylmalate dehydrogenase activity
LZE81_15890	COG3706	GGDEF domain
LZE81_15895	COG1309	transcriptional regulator
LZE81_15900	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
LZE81_15905	COG1538	Outer membrane efflux protein
LZE81_15910	COG1519	Transferase
LZE81_15915	COG1560	Kdo2-lipid A biosynthetic process
LZE81_15985	COG0281	malic enzyme
LZE81_15985	COG0280	phosphate acetyltransferase
LZE81_15990	COG1301	dicarboxylic acid transport
LZE81_16000	COG4191	Histidine kinase
LZE81_16020	COG0642	Histidine kinase
LZE81_16035	COG2851	Citrate transporter
LZE81_16040	COG1028	Short-chain dehydrogenase reductase Sdr
LZE81_16050	COG2211	Major facilitator Superfamily
LZE81_16075	COG1162	GTPase activity
LZE81_16165	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
LZE81_16185	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LZE81_16190	COG0804	urea catabolic process
LZE81_16230	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LZE81_16240	COG3791	Glutathione-dependent formaldehyde-activating
LZE81_16245	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
LZE81_16260	COG2205	protein histidine kinase activity
LZE81_16310	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LZE81_16335	COG0617	tRNA 3'-terminal CCA addition
LZE81_16345	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LZE81_16350	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LZE81_16360	COG0738	Major facilitator superfamily
LZE81_16425	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LZE81_16450	COG0617	tRNA 3'-terminal CCA addition
LZE81_16460	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LZE81_16465	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LZE81_16470	COG1609	Transcriptional regulator
LZE81_16475	COG0738	Major facilitator superfamily
LZE81_16480	COG2188	Transcriptional regulator
LZE81_16495	COG3250	beta-galactosidase activity
LZE81_16510	COG4305	rare lipoprotein A
LZE81_16525	COG1028	Short-chain dehydrogenase reductase Sdr
LZE81_16530	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LZE81_16540	COG4191	Histidine kinase
LZE81_16545	COG0784	Response regulator, receiver
LZE81_16550	COG2205	protein histidine kinase activity
LZE81_16550	COG2202	Pas domain
LZE81_16560	COG2823	Periplasmic or secreted lipoprotein
LZE81_16565	COG0673	inositol 2-dehydrogenase activity
LZE81_16570	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
LZE81_16580	COG1090	epimerase
LZE81_16600	COG1051	belongs to the nudix hydrolase family
LZE81_16600	COG1056	cytidyltransferase-related domain
LZE81_16625	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LZE81_16630	COG0321	lipoyl(octanoyl) transferase activity
LZE81_16660	COG1686	Belongs to the peptidase S11 family
LZE81_16670	COG2951	lytic endotransglycosylase activity
LZE81_16685	COG0772	Belongs to the SEDS family
LZE81_16690	COG0768	penicillin binding
LZE81_16705	COG1077	Cell shape determining protein MreB Mrl
LZE81_16710	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LZE81_16715	COG3284	Transcriptional regulator
LZE81_16725	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
LZE81_16735	COG2010	Cytochrome c
LZE81_16760	COG0596	Alpha beta hydrolase
LZE81_16760	COG0508	dehydrogenase complex catalyzes the overall conversion of
LZE81_16765	COG0308	aminopeptidase N
LZE81_16770	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LZE81_16780	COG2226	methyltransferase
LZE81_16825	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
LZE81_16835	COG2832	Protein of unknown function (DUF454)
LZE81_16850	COG0436	Aminotransferase
LZE81_16855	COG1505	serine-type exopeptidase activity
LZE81_16870	COG1733	regulation of RNA biosynthetic process
LZE81_16890	COG0181	hydroxymethylbilane synthase activity
LZE81_16915	COG0745	RESPONSE REGULATOR receiver
LZE81_16935	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LZE81_16940	COG1640	4-alpha-glucanotransferase
LZE81_16965	COG0243	molybdopterin cofactor binding
LZE81_16970	COG2146	nitrite reductase [NAD(P)H] activity
LZE81_16975	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LZE81_16980	COG2223	nitrite transmembrane transporter activity
LZE81_16985	COG1116	anion transmembrane transporter activity
LZE81_16985	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LZE81_17015	COG3645	SOS response
LZE81_17025	COG0732	type I restriction modification DNA specificity domain
LZE81_17030	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
LZE81_17055	COG2204	response regulator
LZE81_17060	COG4191	Histidine kinase
LZE81_17065	COG0028	Belongs to the TPP enzyme family
LZE81_17080	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LZE81_17095	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
LZE81_17105	COG1028	Short-chain dehydrogenase reductase Sdr
LZE81_17110	COG3685	Protein conserved in bacteria
LZE81_17115	COG3685	Protein conserved in bacteria
LZE81_17125	COG0840	transmembrane signaling receptor activity
LZE81_17165	COG1309	transcriptional regulator
LZE81_17220	COG0366	Alpha amylase catalytic
LZE81_17225	COG0366	Alpha amylase catalytic
LZE81_17235	COG1609	Transcriptional regulator
LZE81_17270	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LZE81_17275	COG1490	D-aminoacyl-tRNA deacylase activity
LZE81_17290	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LZE81_17315	COG3307	-O-antigen
LZE81_17325	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LZE81_17330	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LZE81_17330	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LZE81_17335	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LZE81_17340	COG0242	peptide deformylase activity
LZE81_17345	COG1652	LysM domain
LZE81_17350	COG0758	DNA mediated transformation
LZE81_17365	COG1714	RDD family
LZE81_17370	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LZE81_17370	COG1754	DNA topoisomerase type I activity
LZE81_17375	COG0009	L-threonylcarbamoyladenylate synthase
LZE81_17395	COG1028	Short-chain dehydrogenase reductase Sdr
LZE81_17405	COG0616	signal peptide processing
LZE81_17410	COG0534	Mate efflux family protein
LZE81_17420	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LZE81_17430	COG1252	NADH dehydrogenase
LZE81_17440	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LZE81_17445	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
LZE81_17450	COG2201	protein-glutamate methylesterase activity
LZE81_17455	COG2177	Part of the ABC transporter FtsEX involved in
LZE81_17460	COG2884	Cell division ATP-binding protein ftsE
LZE81_17470	COG3118	belongs to the thioredoxin family
LZE81_17475	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
LZE81_17505	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
LZE81_17555	COG1518	maintenance of DNA repeat elements
LZE81_17560	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
LZE81_17570	COG1652	LysM domain
LZE81_17585	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LZE81_17590	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LZE81_17595	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LZE81_17605	COG5383	Protein conserved in bacteria
LZE81_17645	COG3409	Peptidoglycan-binding domain 1 protein
LZE81_17645	COG3501	Rhs element vgr protein
LZE81_17665	COG4771	TonB-dependent receptor
LZE81_17675	COG4948	Mandelate Racemase Muconate Lactonizing
LZE81_17685	COG0531	amino acid
LZE81_17705	COG2133	pyrroloquinoline quinone binding
LZE81_17720	COG2308	Evidence 4 Homologs of previously reported genes of
LZE81_17735	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LZE81_17755	COG1295	ribonuclease BN
LZE81_17760	COG0358	DNA primase activity
LZE81_17775	COG0109	protoheme IX farnesyltransferase activity
LZE81_17805	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
LZE81_17810	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LZE81_17815	COG1565	acr, cog1565
LZE81_17815	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LZE81_17830	COG1486	melibiose metabolic process
LZE81_17875	COG0793	Belongs to the peptidase S41A family
LZE81_17880	COG4942	peptidase
LZE81_17890	COG2234	aminopeptidase activity
LZE81_17895	COG1064	alcohol dehydrogenase
LZE81_17925	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LZE81_17930	COG0739	heme binding
LZE81_17935	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
LZE81_17945	COG2814	Major facilitator Superfamily
LZE81_17955	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LZE81_17975	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LZE81_17995	COG4221	oxidoreductase activity
LZE81_18015	COG0583	DNA-binding transcription factor activity
LZE81_18020	COG2755	lipolytic protein G-D-S-L family
LZE81_18020	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
LZE81_18025	COG1819	glycosyl
LZE81_18030	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LZE81_18035	COG1166	arginine decarboxylase activity
LZE81_18055	COG2960	long-chain fatty acid transporting porin activity
LZE81_18060	COG0606	chelatase, subunit chli
LZE81_18090	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LZE81_18100	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
LZE81_18115	COG1028	Short-chain dehydrogenase reductase Sdr
LZE81_18135	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LZE81_18150	COG3706	GGDEF domain
LZE81_18150	COG2203	Gaf domain
LZE81_18150	COG4251	negative regulation of phosphorylation
LZE81_18150	COG5001	Diguanylate cyclase
LZE81_18160	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LZE81_18165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LZE81_18180	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LZE81_18195	COG1522	sequence-specific DNA binding
LZE81_18230	COG0714	Associated with various cellular activities
LZE81_18240	COG0754	glutathionylspermidine amidase activity
LZE81_18320	COG2133	pyrroloquinoline quinone binding
LZE81_18330	COG0628	permease
LZE81_18350	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LZE81_18415	COG1199	ATP-dependent helicase activity
LZE81_18475	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
LZE81_18500	COG3104	oligopeptide transport
LZE81_18520	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
LZE81_18535	COG0508	dehydrogenase complex catalyzes the overall conversion of
LZE81_18555	COG0513	Belongs to the DEAD box helicase family
LZE81_18585	COG2354	Protein conserved in bacteria
LZE81_18605	COG1196	nuclear chromosome segregation
LZE81_18605	COG3264	Mechanosensitive ion channel
LZE81_18610	COG0604	alcohol dehydrogenase
LZE81_18610	COG1028	Short-chain dehydrogenase reductase Sdr
LZE81_18610	COG3321	synthase
LZE81_18630	COG1595	DNA-templated transcription, initiation
LZE81_18645	COG0477	Major facilitator Superfamily
LZE81_18650	COG1802	Transcriptional regulator
LZE81_18695	COG1414	Transcriptional regulator
LZE81_18700	COG0738	Major facilitator superfamily
LZE81_18705	COG3254	rhamnose metabolic process
LZE81_18710	COG4948	Mandelate Racemase Muconate Lactonizing
LZE81_18715	COG0179	Fumarylacetoacetate (FAA) hydrolase
LZE81_18720	COG1028	Short-chain dehydrogenase reductase Sdr
LZE81_18750	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LZE81_18765	COG4807	Protein conserved in bacteria
LZE81_18785	COG4773	Receptor
LZE81_18800	COG1506	peptidase
LZE81_18800	COG0823	Involved in the tonB-independent uptake of proteins
LZE81_18880	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LZE81_18905	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LZE81_18910	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LZE81_18915	COG0753	catalase activity
LZE81_18940	COG1136	(ABC) transporter
LZE81_18945	COG0577	efflux transmembrane transporter activity
LZE81_18980	COG0180	Tryptophanyl-tRNA synthetase
LZE81_19015	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
LZE81_19020	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
LZE81_19020	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
LZE81_19030	COG3228	Belongs to the MtfA family
LZE81_19060	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LZE81_19085	COG2084	Dehydrogenase
LZE81_19090	COG1902	pentaerythritol trinitrate reductase activity
LZE81_19100	COG2814	Major facilitator Superfamily
LZE81_19105	COG0583	DNA-binding transcription factor activity
LZE81_19120	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LZE81_19125	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LZE81_19135	COG1764	response to oxidative stress
LZE81_19140	COG1846	Transcriptional regulator
LZE81_19145	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
LZE81_19155	COG0697	spore germination
LZE81_19160	COG0523	cobalamin synthesis protein
LZE81_19170	COG1742	UPF0060 membrane protein
LZE81_19180	COG3245	cytochrome
LZE81_19190	COG1960	acyl-CoA dehydrogenase activity
LZE81_19195	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LZE81_19230	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LZE81_19235	COG3387	PFAM Glycoside hydrolase 15-related
LZE81_19240	COG0745	RESPONSE REGULATOR receiver
LZE81_19270	COG1404	Belongs to the peptidase S8 family
LZE81_19280	COG3100	YcgL domain-containing protein
LZE81_19285	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LZE81_19295	COG0463	Glycosyl transferase, family 2
LZE81_19330	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LZE81_19345	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LZE81_19370	COG1294	oxidase, subunit
LZE81_19375	COG1271	oxidase subunit
LZE81_19395	COG0408	coproporphyrinogen oxidase activity
LZE81_19405	COG2323	membrane
LZE81_19410	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LZE81_19410	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LZE81_19430	COG0589	response to stress
LZE81_19455	COG0210	DNA helicase
LZE81_19505	COG0463	Glycosyl transferase, family 2
LZE81_19515	COG1475	DNA binding
LZE81_19520	COG1192	Involved in chromosome partitioning
LZE81_19525	COG0357	Ribosomal RNA small subunit methyltransferase G
LZE81_19535	COG2091	lysine biosynthetic process via aminoadipic acid
LZE81_19560	COG0477	Major facilitator Superfamily
LZE81_19580	COG1971	Probably functions as a manganese efflux pump
LZE81_19585	COG2205	protein histidine kinase activity
LZE81_19600	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LZE81_19605	COG3459	Glycosyltransferase 36 associated
LZE81_19610	COG2211	Major facilitator Superfamily
LZE81_19615	COG3265	gluconokinase activity
LZE81_19635	COG2911	Protein conserved in bacteria
LZE81_19640	COG0729	surface antigen
LZE81_19660	COG3132	Protein of unknown function, DUF480
LZE81_19690	COG0284	orotidine-5'-phosphate decarboxylase activity
LZE81_19705	COG1609	Transcriptional regulator
LZE81_19715	COG2937	Belongs to the GPAT DAPAT family
LZE81_19740	COG2211	Major facilitator Superfamily
LZE81_19755	COG3693	PFAM glycoside hydrolase, family 10
LZE81_19760	COG1904	glucuronate isomerase
LZE81_19775	COG3386	PFAM SMP-30 Gluconolaconase
LZE81_19795	COG0246	Mannitol dehydrogenase
LZE81_19800	COG1472	Belongs to the glycosyl hydrolase 3 family
LZE81_19810	COG4948	Mandelate Racemase Muconate Lactonizing
LZE81_19820	COG3661	Belongs to the glycosyl hydrolase 67 family
LZE81_19830	COG2115	Belongs to the xylose isomerase family
LZE81_19835	COG0037	tRNA processing
LZE81_19855	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
LZE81_19865	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LZE81_19875	COG0805	protein transport
LZE81_19885	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LZE81_19885	COG0519	Catalyzes the synthesis of GMP from XMP
LZE81_19890	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LZE81_19910	COG0210	DNA helicase
LZE81_19915	COG1435	thymidine kinase activity
LZE81_19925	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
LZE81_19940	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LZE81_19955	COG1119	ATPase activity
LZE81_19970	COG0706	membrane insertase activity
LZE81_19975	COG0594	ribonuclease P activity