locus-tag	class	description
LV507_00010	COG0592	DNA-directed DNA polymerase activity
LV507_00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LV507_00020	COG0187	DNA topoisomerase II activity
LV507_00025	COG1266	CAAX protease self-immunity
LV507_00030	COG0501	Belongs to the peptidase M48B family
LV507_00060	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
LV507_00070	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LV507_00085	COG1280	lysine exporter protein (LysE YggA)
LV507_00100	COG4772	TonB-dependent receptor
LV507_00110	COG3284	Transcriptional regulator
LV507_00120	COG1012	belongs to the aldehyde dehydrogenase family
LV507_00160	COG1304	FMN binding
LV507_00165	COG2186	Transcriptional regulator
LV507_00185	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LV507_00265	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LV507_00285	COG4771	TonB-dependent receptor
LV507_00330	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
LV507_00345	COG3507	Belongs to the glycosyl hydrolase 43 family
LV507_00350	COG1609	Transcriptional regulator
LV507_00360	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
LV507_00365	COG1028	Short-chain dehydrogenase reductase Sdr
LV507_00380	COG3186	Phenylalanine-4-hydroxylase
LV507_00385	COG1522	sequence-specific DNA binding
LV507_00420	COG1752	Esterase of the alpha-beta hydrolase superfamily
LV507_00435	COG0671	phosphoesterase, PA-phosphatase related
LV507_00450	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LV507_00485	COG1929	Belongs to the glycerate kinase type-1 family
LV507_00495	COG0531	amino acid
LV507_00500	COG4566	intracellular signal transduction
LV507_00505	COG4191	Histidine kinase
LV507_00525	COG1322	Protein conserved in bacteria
LV507_00530	COG0386	Belongs to the glutathione peroxidase family
LV507_00535	COG2853	Lipoprotein
LV507_00550	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
LV507_00555	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LV507_00560	COG1127	ABC transporter
LV507_00565	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
LV507_00570	COG1074	ATP-dependent DNA helicase activity
LV507_00575	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LV507_00595	COG0537	adenosine 5'-monophosphoramidase activity
LV507_00600	COG1074	ATP-dependent DNA helicase activity
LV507_00610	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
LV507_00660	COG0477	Major facilitator Superfamily
LV507_00665	COG0302	gtp cyclohydrolase
LV507_00690	COG0730	response to heat
LV507_00705	COG2951	lytic endotransglycosylase activity
LV507_00770	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
LV507_00775	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
LV507_00780	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
LV507_00785	COG0493	'glutamate synthase
LV507_00790	COG0069	glutamate synthase activity
LV507_00790	COG0070	glutamate synthase
LV507_00790	COG0067	glutamate synthase
LV507_00835	COG1205	dead DEAH box helicase
LV507_00835	COG1111	helicase
LV507_00865	COG2271	Major facilitator Superfamily
LV507_00905	COG1192	Involved in chromosome partitioning
LV507_00910	COG2062	phosphohistidine phosphatase, SixA
LV507_00920	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LV507_00925	COG2050	protein possibly involved in aromatic compounds catabolism
LV507_00935	COG2267	carboxylic ester hydrolase activity
LV507_00945	COG1881	PFAM PEBP family protein
LV507_00950	COG1968	undecaprenyl-diphosphatase activity
LV507_00955	COG0174	glutamine synthetase
LV507_00960	COG0347	Belongs to the P(II) protein family
LV507_00965	COG0004	ammonium transporteR
LV507_00970	COG3852	Histidine kinase
LV507_00975	COG2204	response regulator
LV507_00980	COG2032	superoxide dismutase activity
LV507_00985	COG2032	superoxide dismutase activity
LV507_00995	COG0183	Belongs to the thiolase family
LV507_01035	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
LV507_01040	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
LV507_01050	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
LV507_01060	COG0612	Peptidase, M16
LV507_01070	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LV507_01075	COG3177	Filamentation induced by cAMP protein fic
LV507_01090	COG0596	Alpha beta hydrolase
LV507_01100	COG0727	PFAM Uncharacterised protein family (UPF0153)
LV507_01105	COG0318	PFAM AMP-dependent synthetase and ligase
LV507_01120	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LV507_01130	COG1181	Belongs to the D-alanine--D-alanine ligase family
LV507_01145	COG4232	protein-disulfide reductase activity
LV507_01150	COG0564	pseudouridine synthase activity
LV507_01170	COG0339	signal peptide processing
LV507_01190	COG0583	DNA-binding transcription factor activity
LV507_01195	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
LV507_01200	COG2224	Isocitrate lyase
LV507_01235	COG0659	secondary active sulfate transmembrane transporter activity
LV507_01270	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LV507_01275	COG2130	NADP-dependent
LV507_01290	COG1187	pseudouridine synthase activity
LV507_01305	COG1643	Atp-dependent helicase
LV507_01310	COG0084	hydrolase, TatD family'
LV507_01350	COG0842	Transport permease protein
LV507_01355	COG1131	(ABC) transporter
LV507_01360	COG0633	Ferredoxin
LV507_01360	COG0543	2 iron, 2 sulfur cluster binding
LV507_01370	COG1476	TRANSCRIPTIONal
LV507_01380	COG4555	ABC transporter
LV507_01400	COG0625	glutathione transferase activity
LV507_01445	COG0530	calcium, potassium:sodium antiporter activity
LV507_01450	COG1320	monovalent cation:proton antiporter activity
LV507_01455	COG2212	antiporter activity
LV507_01460	COG1863	multisubunit Na H antiporter MnhE subunit
LV507_01465	COG0651	ATP synthesis coupled electron transport
LV507_01470	COG1006	Multisubunit Na H antiporter MnhC subunit
LV507_01475	COG2111	Na H antiporter
LV507_01475	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LV507_01480	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LV507_01495	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
LV507_01510	COG1597	lipid kinase activity
LV507_01540	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LV507_01545	COG0134	indole-3-glycerol-phosphate synthase activity
LV507_01555	COG0730	response to heat
LV507_01560	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LV507_01565	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
LV507_01580	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
LV507_01605	COG1051	belongs to the nudix hydrolase family
LV507_01610	COG2906	2 iron, 2 sulfur cluster binding
LV507_01655	COG2816	NAD+ diphosphatase activity
LV507_01695	COG2814	Major facilitator Superfamily
LV507_01700	COG1289	transmembrane transporter activity
LV507_01705	COG0151	Belongs to the GarS family
LV507_01710	COG0138	bifunctional purine biosynthesis protein purh
LV507_01715	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LV507_01740	COG4589	Belongs to the CDS family
LV507_01745	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
LV507_01765	COG2264	protein methyltransferase activity
LV507_01780	COG0439	Biotin carboxylase
LV507_01785	COG0511	ligase activity, forming carbon-carbon bonds
LV507_01790	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
LV507_01800	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LV507_01805	COG4232	protein-disulfide reductase activity
LV507_01810	COG1324	tolerance protein
LV507_01825	COG0459	protein refolding
LV507_01830	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LV507_01855	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
LV507_01870	COG0584	glycerophosphoryl diester phosphodiesterase
LV507_01895	COG2353	YceI-like domain
LV507_01910	COG0840	transmembrane signaling receptor activity
LV507_01995	COG2267	carboxylic ester hydrolase activity
LV507_02020	COG0697	spore germination
LV507_02025	COG1113	amino acid transport
LV507_02030	COG0598	Magnesium transport protein CorA
LV507_02040	COG2207	Transcriptional regulator
LV507_02055	COG0741	lytic transglycosylase activity
LV507_02070	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
LV507_02070	COG5297	Belongs to the glycosyl hydrolase family 6
LV507_02080	COG0531	amino acid
LV507_02100	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
LV507_02105	COG3275	phosphorelay sensor kinase activity
LV507_02130	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LV507_02140	COG2076	Multidrug Resistance protein
LV507_02150	COG4106	trans-aconitate 2-methyltransferase activity
LV507_02180	COG5001	Diguanylate cyclase
LV507_02185	COG2146	nitrite reductase [NAD(P)H] activity
LV507_02210	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LV507_02215	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LV507_02225	COG0667	Aldo Keto reductase
LV507_02250	COG3384	dioxygenase
LV507_02260	COG1573	uracil-dna glycosylase
LV507_02265	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
LV507_02275	COG0025	NhaP-type Na H and K H
LV507_02280	COG1131	(ABC) transporter
LV507_02285	COG0842	Transport permease protein
LV507_02345	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LV507_02370	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LV507_02370	COG2205	protein histidine kinase activity
LV507_02395	COG1187	pseudouridine synthase activity
LV507_02405	COG1666	GTP binding
LV507_02410	COG0697	spore germination
LV507_02415	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LV507_02455	COG0508	dehydrogenase complex catalyzes the overall conversion of
LV507_02460	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LV507_02475	COG0356	it plays a direct role in the translocation of protons across the membrane
LV507_02485	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LV507_02495	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LV507_02510	COG0355	proton-transporting ATP synthase activity, rotational mechanism
LV507_02525	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LV507_02560	COG1136	(ABC) transporter
LV507_02560	COG0577	efflux transmembrane transporter activity
LV507_02565	COG1136	(ABC) transporter
LV507_02565	COG0577	efflux transmembrane transporter activity
LV507_02570	COG1136	(ABC) transporter
LV507_02580	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LV507_02595	COG2132	Multicopper oxidase
LV507_02610	COG2217	Heavy metal translocating P-type atpase
LV507_02620	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LV507_02625	COG0339	signal peptide processing
LV507_02650	COG0546	phosphoglycolate phosphatase activity
LV507_02660	COG4206	TonB-dependent receptor
LV507_02670	COG1956	GAF domain-containing protein
LV507_02675	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
LV507_02685	COG0720	synthase
LV507_02700	COG0625	glutathione transferase activity
LV507_02730	COG0626	cystathionine gamma-synthase activity
LV507_02745	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LV507_02750	COG1216	Glycosyl transferase, family 2
LV507_02750	COG0438	transferase activity, transferring glycosyl groups
LV507_02755	COG0438	transferase activity, transferring glycosyl groups
LV507_02755	COG1216	Glycosyl transferase, family 2
LV507_02790	COG0493	'glutamate synthase
LV507_02805	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LV507_02810	COG0300	oxidoreductase activity
LV507_02815	COG0277	FAD linked oxidase domain protein
LV507_02820	COG0546	phosphoglycolate phosphatase activity
LV507_02820	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
LV507_02835	COG2086	electron transfer activity
LV507_02860	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
LV507_02860	COG0662	Cupin 2, conserved barrel domain protein
LV507_02865	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LV507_02870	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LV507_02900	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
LV507_02900	COG3218	ABC-type transport auxiliary lipoprotein component
LV507_02905	COG1127	ABC transporter
LV507_02910	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LV507_02925	COG0442	prolyl-tRNA aminoacylation
LV507_02935	COG1183	phosphatidylcholine synthase activity
LV507_02970	COG2927	DNA polymerase III (CHI subunit)
LV507_02975	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LV507_03000	COG4974	Belongs to the 'phage' integrase family
LV507_03005	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LV507_03010	COG0047	phosphoribosylformylglycinamidine synthase activity
LV507_03010	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LV507_03015	COG0840	transmembrane signaling receptor activity
LV507_03025	COG5295	Hep Hag repeat protein
LV507_03030	COG1404	Belongs to the peptidase S8 family
LV507_03035	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LV507_03040	COG1459	type II secretion system
LV507_03045	COG2165	general secretion pathway protein
LV507_03050	COG4970	Tfp pilus assembly protein FimT
LV507_03055	COG2165	general secretion pathway protein
LV507_03060	COG4795	General secretion pathway protein
LV507_03065	COG3156	type II secretion system protein K
LV507_03070	COG3166	PFAM Fimbrial assembly family protein
LV507_03085	COG1450	Type ii and iii secretion system protein
LV507_03095	COG2188	Transcriptional regulator
LV507_03145	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
LV507_03155	COG1215	transferase activity, transferring glycosyl groups
LV507_03175	COG1696	Membrane protein involved in D-alanine export
LV507_03185	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LV507_03210	COG0242	peptide deformylase activity
LV507_03215	COG0488	(ABC) transporter
LV507_03220	COG0477	Major facilitator Superfamily
LV507_03250	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LV507_03260	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LV507_03260	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LV507_03275	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
LV507_03280	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LV507_03285	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
LV507_03305	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
LV507_03310	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
LV507_03320	COG2205	protein histidine kinase activity
LV507_03325	COG0745	RESPONSE REGULATOR receiver
LV507_03330	COG0277	FAD linked oxidase domain protein
LV507_03340	COG0792	nuclease activity
LV507_03375	COG2001	Belongs to the MraZ family
LV507_03380	COG0275	rRNA processing
LV507_03385	COG3116	cell division
LV507_03400	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LV507_03425	COG1181	Belongs to the D-alanine--D-alanine ligase family
LV507_03430	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
LV507_03440	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LV507_03445	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
LV507_03455	COG0739	heme binding
LV507_03470	COG0494	nUDIX hydrolase
LV507_03480	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
LV507_03545	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LV507_03565	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LV507_03585	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LV507_03590	COG0667	Aldo Keto reductase
LV507_03600	COG4771	TonB-dependent receptor
LV507_03620	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
LV507_03625	COG4181	ATPase activity
LV507_03640	COG0642	Histidine kinase
LV507_03650	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
LV507_03655	COG0861	Integral membrane protein TerC family
LV507_03660	COG1704	LemA family
LV507_03695	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
LV507_03700	COG2967	ApaG domain
LV507_03705	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LV507_03710	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
LV507_03715	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LV507_03730	COG2096	Adenosyltransferase
LV507_03740	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LV507_03745	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LV507_03785	COG0697	spore germination
LV507_03790	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LV507_03820	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LV507_03835	COG0583	DNA-binding transcription factor activity
LV507_03840	COG3634	alkyl hydroperoxide reductase activity
LV507_03910	COG0488	(ABC) transporter
LV507_03960	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LV507_03965	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
LV507_03980	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
LV507_03990	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LV507_04000	COG0193	aminoacyl-tRNA hydrolase activity
LV507_04005	COG0012	GTP binding
LV507_04025	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LV507_04035	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LV507_04040	COG0250	Participates in transcription elongation, termination and antitermination
LV507_04045	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LV507_04060	COG0222	ribosome binding
LV507_04070	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LV507_04085	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LV507_04090	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LV507_04095	COG0051	transcription antitermination factor activity, RNA binding
LV507_04105	COG0088	Forms part of the polypeptide exit tunnel
LV507_04110	COG0089	rRNA binding
LV507_04115	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LV507_04140	COG0255	Belongs to the universal ribosomal protein uL29 family
LV507_04145	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LV507_04155	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
LV507_04160	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LV507_04165	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LV507_04190	COG1841	ribosomal large subunit assembly
LV507_04200	COG0201	protein transport
LV507_04225	COG0203	ribosomal protein L17
LV507_04230	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
LV507_04240	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
LV507_04255	COG1217	gtp-binding protein TYPA
LV507_04260	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LV507_04270	COG0039	L-malate dehydrogenase activity
LV507_04295	COG0625	glutathione transferase activity
LV507_04340	COG0446	pyridine nucleotide-disulphide oxidoreductase
LV507_04340	COG1902	pentaerythritol trinitrate reductase activity
LV507_04355	COG0667	Aldo Keto reductase
LV507_04375	COG2885	chlorophyll binding
LV507_04385	COG1187	pseudouridine synthase activity
LV507_04390	COG0156	8-amino-7-oxononanoate synthase activity
LV507_04395	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
LV507_04400	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
LV507_04405	COG4208	sulfate ABC transporter
LV507_04410	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
LV507_04430	COG0588	phosphoglycerate mutase activity
LV507_04435	COG0285	dihydrofolate synthase activity
LV507_04455	COG2833	Protein of unknown function (DUF455)
LV507_04470	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LV507_04480	COG0438	transferase activity, transferring glycosyl groups
LV507_04485	COG0248	Ppx GppA phosphatase
LV507_04490	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
LV507_04505	COG4783	chaperone-mediated protein folding
LV507_04520	COG0473	3-isopropylmalate dehydrogenase activity
LV507_04560	COG0544	peptidyl-prolyl cis-trans isomerase activity
LV507_04570	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LV507_04605	COG1388	LysM domain
LV507_04605	COG3942	CHAP domain
LV507_04610	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LV507_04620	COG0328	RNA-DNA hybrid ribonuclease activity
LV507_04625	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LV507_04630	COG0631	protein serine/threonine phosphatase activity
LV507_04650	COG0859	PFAM glycosyl transferase family 9
LV507_04660	COG1234	tRNA 3'-trailer cleavage
LV507_04665	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
LV507_04675	COG0315	cyclic pyranopterin monophosphate synthase activity
LV507_04680	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
LV507_04685	COG0314	molybdopterin synthase activity
LV507_04765	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
LV507_04790	COG1773	rubredoxin
LV507_04805	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
LV507_04815	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LV507_04840	COG3079	Belongs to the UPF0149 family
LV507_04845	COG0006	proline dipeptidase activity
LV507_04850	COG0006	proline dipeptidase activity
LV507_04870	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LV507_04875	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LV507_04880	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
LV507_04885	COG1561	YicC-like family, N-terminal region
LV507_04890	COG0194	GDP metabolic process
LV507_04895	COG1758	RNA polymerase activity
LV507_04900	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LV507_04910	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LV507_04920	COG0254	rRNA binding
LV507_04925	COG0372	Belongs to the citrate synthase family
LV507_04940	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
LV507_04970	COG0714	Associated with various cellular activities
LV507_05000	COG1301	dicarboxylic acid transport
LV507_05005	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LV507_05035	COG0739	heme binding
LV507_05040	COG1376	ErfK ybiS ycfS ynhG family protein
LV507_05075	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
LV507_05080	COG4149	molybdate abc transporter
LV507_05085	COG0725	ABC transporter, periplasmic molybdate-binding protein
LV507_05095	COG0640	Transcriptional regulator
LV507_05120	COG3047	cAMP biosynthetic process
LV507_05125	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LV507_05180	COG0469	pyruvate kinase activity
LV507_05185	COG3588	fructose-bisphosphate aldolase
LV507_05190	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
LV507_05225	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
LV507_05240	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LV507_05240	COG1648	precorrin-2 dehydrogenase activity
LV507_05255	COG0784	Response regulator, receiver
LV507_05255	COG2198	Histidine kinase
LV507_05255	COG2205	protein histidine kinase activity
LV507_05260	COG1393	Belongs to the ArsC family
LV507_05290	COG0175	sulfate reduction
LV507_05295	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LV507_05300	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LV507_05310	COG0529	Catalyzes the synthesis of activated sulfate
LV507_05310	COG2895	sulfate adenylyltransferase (ATP) activity
LV507_05315	COG0840	transmembrane signaling receptor activity
LV507_05345	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LV507_05360	COG1609	Transcriptional regulator
LV507_05375	COG0179	Fumarylacetoacetate (FAA) hydrolase
LV507_05390	COG0471	metal ion transport
LV507_05390	COG3273	potassium ion transport
LV507_05400	COG2022	thiamine diphosphate biosynthetic process
LV507_05425	COG0174	glutamine synthetase
LV507_05430	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
LV507_05440	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
LV507_05455	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
LV507_05480	COG3511	phospholipase C
LV507_05490	COG0189	ligase activity
LV507_05500	COG0745	RESPONSE REGULATOR receiver
LV507_05515	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
LV507_05575	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
LV507_05575	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LV507_05585	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LV507_05600	COG1174	glycine betaine transport
LV507_05605	COG1125	glycine betaine transport
LV507_05615	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LV507_05620	COG0564	pseudouridine synthase activity
LV507_05645	COG3387	PFAM Glycoside hydrolase 15-related
LV507_05670	COG0454	-acetyltransferase
LV507_05700	COG0542	response to heat
LV507_05725	COG0019	diaminopimelate decarboxylase activity
LV507_05730	COG4264	IucA IucC family
LV507_05735	COG2814	Major facilitator Superfamily
LV507_05740	COG4264	IucA IucC family
LV507_05750	COG4772	TonB-dependent receptor
LV507_05765	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LV507_05765	COG4651	solute:proton antiporter activity
LV507_05825	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LV507_05825	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LV507_05845	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
LV507_05885	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LV507_05890	COG1404	Belongs to the peptidase S8 family
LV507_05925	COG1295	ribonuclease BN
LV507_05930	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LV507_05950	COG0521	Mo-molybdopterin cofactor biosynthetic process
LV507_06055	COG3537	Alpha-1,2-mannosidase
LV507_06080	COG1472	Belongs to the glycosyl hydrolase 3 family
LV507_06090	COG3525	Glycosyl hydrolase, family 20, catalytic domain
LV507_06095	COG1388	LysM domain
LV507_06095	COG3858	chitin binding
LV507_06110	COG0837	glucose binding
LV507_06120	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LV507_06130	COG0494	nUDIX hydrolase
LV507_06135	COG1218	3'(2'),5'-bisphosphate nucleotidase
LV507_06140	COG3956	TIGRFAM MazG family protein
LV507_06145	COG1742	UPF0060 membrane protein
LV507_06150	COG0330	HflC and HflK could
LV507_06185	COG0697	spore germination
LV507_06215	COG2124	cytochrome p450
LV507_06220	COG2124	cytochrome p450
LV507_06225	COG1141	Ferredoxin
LV507_06230	COG1028	Short-chain dehydrogenase reductase Sdr
LV507_06235	COG2124	cytochrome p450
LV507_06240	COG0142	geranyltranstransferase activity
LV507_06245	COG1657	PFAM Prenyltransferase squalene oxidase
LV507_06255	COG1304	FMN binding
LV507_06275	COG4206	TonB-dependent receptor
LV507_06285	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
LV507_06290	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LV507_06295	COG0463	Glycosyl transferase, family 2
LV507_06300	COG0517	IMP dehydrogenase activity
LV507_06305	COG2982	Protein involved in outer membrane biogenesis
LV507_06310	COG1272	protein, Hemolysin III
LV507_06315	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
LV507_06325	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LV507_06330	COG0626	cystathionine gamma-synthase activity
LV507_06335	COG0460	homoserine dehydrogenase
LV507_06335	COG0527	aspartate kinase activity
LV507_06340	COG2267	carboxylic ester hydrolase activity
LV507_06350	COG1760	l-serine dehydratase
LV507_06365	COG3038	cytochrome b561
LV507_06385	COG2814	Major facilitator Superfamily
LV507_06390	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
LV507_06400	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LV507_06405	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LV507_06420	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LV507_06480	COG0519	Catalyzes the synthesis of GMP from XMP
LV507_06495	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LV507_06515	COG0840	transmembrane signaling receptor activity
LV507_06525	COG1113	amino acid transport
LV507_06545	COG2239	Acts as a magnesium transporter
LV507_06550	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LV507_06555	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LV507_06565	COG1660	Displays ATPase and GTPase activities
LV507_06575	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LV507_06590	COG1137	ATPase activity
LV507_06605	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
LV507_06650	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LV507_06675	COG0628	permease
LV507_06685	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LV507_06690	COG3178	'Phosphotransferase
LV507_06705	COG1555	photosystem II stabilization
LV507_06730	COG1477	protein flavinylation
LV507_06755	COG4774	siderophore transport
LV507_06760	COG2146	nitrite reductase [NAD(P)H] activity
LV507_06770	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LV507_06775	COG0719	Fe-S assembly protein
LV507_06780	COG0396	ATPase activity
LV507_06785	COG0719	Fe-S assembly protein
LV507_06800	COG0693	protein deglycase activity
LV507_06815	COG0739	heme binding
LV507_06830	COG1764	response to oxidative stress
LV507_06840	COG0384	phenazine biosynthesis protein PhzF
LV507_06845	COG0527	aspartate kinase activity
LV507_06870	COG0142	geranyltranstransferase activity
LV507_06875	COG0629	single-stranded DNA binding
LV507_06880	COG3550	peptidyl-serine autophosphorylation
LV507_06895	COG3104	oligopeptide transport
LV507_06900	COG1297	OPT oligopeptide transporter protein
LV507_06905	COG1506	peptidase
LV507_06905	COG0823	Involved in the tonB-independent uptake of proteins
LV507_06925	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LV507_06930	COG2879	small protein
LV507_06935	COG1966	Carbon starvation protein
LV507_06970	COG2211	Major facilitator Superfamily
LV507_07005	COG2203	Gaf domain
LV507_07005	COG3706	GGDEF domain
LV507_07005	COG4251	negative regulation of phosphorylation
LV507_07005	COG5001	Diguanylate cyclase
LV507_07010	COG0835	chemotaxis
LV507_07015	COG0840	transmembrane signaling receptor activity
LV507_07020	COG0840	transmembrane signaling receptor activity
LV507_07025	COG0840	transmembrane signaling receptor activity
LV507_07030	COG2198	Histidine kinase
LV507_07030	COG0643	Histidine kinase
LV507_07040	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LV507_07055	COG3878	Protein conserved in bacteria
LV507_07060	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
LV507_07070	COG2205	protein histidine kinase activity
LV507_07080	COG4452	Inner membrane protein CreD
LV507_07105	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LV507_07110	COG0735	belongs to the Fur family
LV507_07145	COG1529	Aldehyde oxidase and xanthine dehydrogenase
LV507_07150	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
LV507_07155	COG2080	2 iron, 2 sulfur cluster binding
LV507_07265	COG1187	pseudouridine synthase activity
LV507_07290	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LV507_07315	COG1132	(ABC) transporter
LV507_07345	COG0583	DNA-binding transcription factor activity
LV507_07385	COG1981	membrane
LV507_07410	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LV507_07415	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LV507_07425	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LV507_07430	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LV507_07435	COG0750	zinc metalloprotease
LV507_07440	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
LV507_07445	COG0575	Belongs to the CDS family
LV507_07450	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LV507_07460	COG0528	UMP kinase activity
LV507_07470	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LV507_07510	COG0024	Methionine aminopeptidase
LV507_07525	COG1393	Belongs to the ArsC family
LV507_07530	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LV507_07540	COG0367	asparagine synthase
LV507_07575	COG1566	PFAM secretion protein HlyD family protein
LV507_07580	COG2814	Major facilitator Superfamily
LV507_07615	COG0557	exoribonuclease II activity
LV507_07625	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LV507_07635	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LV507_07655	COG0704	Plays a role in the regulation of phosphate uptake
LV507_07665	COG0581	inorganic phosphate transmembrane transporter activity
LV507_07675	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LV507_07680	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LV507_07700	COG0659	secondary active sulfate transmembrane transporter activity
LV507_07705	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LV507_07715	COG1024	Enoyl-CoA hydratase
LV507_07770	COG0784	Response regulator, receiver
LV507_07770	COG2205	protein histidine kinase activity
LV507_07770	COG5002	protein histidine kinase activity
LV507_07775	COG2733	membrane
LV507_07795	COG0686	Belongs to the AlaDH PNT family
LV507_07800	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LV507_07805	COG1396	sequence-specific DNA binding
LV507_07805	COG1917	Cupin 2, conserved barrel domain protein
LV507_07810	COG1012	belongs to the aldehyde dehydrogenase family
LV507_07830	COG2223	nitrite transmembrane transporter activity
LV507_07840	COG0243	molybdopterin cofactor binding
LV507_07865	COG0477	Major facilitator Superfamily
LV507_07875	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LV507_07880	COG0174	glutamine synthetase
LV507_07885	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
LV507_07890	COG0174	glutamine synthetase
LV507_07900	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
LV507_07925	COG3842	ATPase activity
LV507_07930	COG1176	ABC-type spermidine putrescine transport system, permease component I
LV507_07935	COG1177	transmembrane transport
LV507_07940	COG1012	belongs to the aldehyde dehydrogenase family
LV507_07955	COG4535	Mg2 and Co2 transporter CorC
LV507_07970	COG1702	phosphate starvation-inducible protein PhoH
LV507_07985	COG0741	lytic transglycosylase activity
LV507_07990	COG0723	plastoquinol--plastocyanin reductase activity
LV507_07995	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
LV507_08005	COG2857	Cytochrome c1
LV507_08010	COG0625	glutathione transferase activity
LV507_08015	COG2969	positive regulation of protein catabolic process
LV507_08055	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
LV507_08060	COG1028	Short-chain dehydrogenase reductase Sdr
LV507_08065	COG2095	MarC family integral membrane protein
LV507_08075	COG1611	Belongs to the LOG family
LV507_08080	COG3275	phosphorelay sensor kinase activity
LV507_08295	COG3179	chitinase
LV507_08340	COG4695	Portal protein
LV507_08395	COG0556	nucleotide-excision repair
LV507_08425	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LV507_08435	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LV507_08440	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LV507_08490	COG0438	transferase activity, transferring glycosyl groups
LV507_08495	COG0438	transferase activity, transferring glycosyl groups
LV507_08505	COG0438	transferase activity, transferring glycosyl groups
LV507_08525	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LV507_08535	COG1960	acyl-CoA dehydrogenase activity
LV507_08570	COG1570	exodeoxyribonuclease VII activity
LV507_08575	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LV507_08580	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LV507_08580	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LV507_08585	COG0802	atpase or kinase
LV507_08590	COG0860	N-Acetylmuramoyl-L-alanine amidase
LV507_08595	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LV507_08620	COG1028	Short-chain dehydrogenase reductase Sdr
LV507_08640	COG2081	HI0933 family
LV507_08645	COG4681	YaeQ
LV507_08650	COG0564	pseudouridine synthase activity
LV507_08660	COG0625	glutathione transferase activity
LV507_08665	COG0657	acetylesterase activity
LV507_08670	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
LV507_08695	COG0513	Belongs to the DEAD box helicase family
LV507_08700	COG0488	(ABC) transporter
LV507_08720	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LV507_08730	COG1472	Belongs to the glycosyl hydrolase 3 family
LV507_08775	COG1846	Transcriptional regulator
LV507_08790	COG0386	Belongs to the glutathione peroxidase family
LV507_08875	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
LV507_08880	COG0084	hydrolase, TatD family'
LV507_08895	COG1960	acyl-CoA dehydrogenase activity
LV507_08905	COG0305	Participates in initiation and elongation during chromosome replication
LV507_08910	COG0415	Belongs to the DNA photolyase family
LV507_08925	COG0583	DNA-binding transcription factor activity
LV507_08940	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LV507_08980	COG1404	Belongs to the peptidase S8 family
LV507_08985	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
LV507_08990	COG2867	negative regulation of translational initiation
LV507_09000	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LV507_09005	COG0735	belongs to the Fur family
LV507_09010	COG0497	DNA recombination
LV507_09015	COG1420	regulation of RNA biosynthetic process
LV507_09020	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LV507_09025	COG0443	Heat shock 70 kDa protein
LV507_09030	COG0484	heat shock protein binding
LV507_09035	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
LV507_09040	COG0287	Prephenate dehydrogenase
LV507_09040	COG1605	Chorismate mutase
LV507_09050	COG1132	(ABC) transporter
LV507_09085	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LV507_09115	COG2166	iron-sulfur cluster assembly
LV507_09130	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LV507_09135	COG0137	argininosuccinate synthase activity
LV507_09140	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LV507_09145	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
LV507_09155	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
LV507_09160	COG0165	Argininosuccinate lyase
LV507_09180	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LV507_09205	COG1501	Belongs to the glycosyl hydrolase 31 family
LV507_09215	COG1070	Carbohydrate kinase
LV507_09220	COG2115	Belongs to the xylose isomerase family
LV507_09225	COG0477	Major facilitator Superfamily
LV507_09230	COG0860	N-Acetylmuramoyl-L-alanine amidase
LV507_09250	COG0617	tRNA 3'-terminal CCA addition
LV507_09260	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
LV507_09275	COG0166	Belongs to the GPI family
LV507_09350	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
LV507_09365	COG0671	phosphoesterase, PA-phosphatase related
LV507_09390	COG0812	UDP-N-acetylmuramate dehydrogenase activity
LV507_09395	COG0167	dihydroorotate dehydrogenase activity
LV507_09410	COG1012	belongs to the aldehyde dehydrogenase family
LV507_09425	COG0460	homoserine dehydrogenase
LV507_09425	COG0527	aspartate kinase activity
LV507_09435	COG2951	lytic endotransglycosylase activity
LV507_09445	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
LV507_09455	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LV507_09460	COG0124	histidyl-tRNA synthetase
LV507_09470	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
LV507_09475	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LV507_09480	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LV507_09490	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LV507_09505	COG0140	phosphoribosyl-ATP diphosphatase activity
LV507_09505	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
LV507_09520	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
LV507_09525	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
LV507_09530	COG0235	Class ii aldolase
LV507_09535	COG0531	amino acid
LV507_09540	COG0531	amino acid
LV507_09555	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LV507_09560	COG0277	FAD linked oxidase domain protein
LV507_09580	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LV507_09595	COG1024	Enoyl-CoA hydratase
LV507_09650	COG1741	Belongs to the pirin family
LV507_09655	COG0583	DNA-binding transcription factor activity
LV507_09675	COG0351	phosphomethylpyrimidine kinase
LV507_09675	COG0352	thiamine-phosphate diphosphorylase activity
LV507_09690	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
LV507_09695	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LV507_09705	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LV507_09715	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
LV507_09720	COG3734	2-keto-3-deoxy-galactonokinase
LV507_09735	COG0800	Aldolase
LV507_09770	COG0784	Response regulator, receiver
LV507_09770	COG2198	Histidine kinase
LV507_09770	COG2205	protein histidine kinase activity
LV507_09775	COG1024	Enoyl-CoA hydratase
LV507_09780	COG0318	PFAM AMP-dependent synthetase and ligase
LV507_09810	COG3706	GGDEF domain
LV507_09835	COG0840	transmembrane signaling receptor activity
LV507_09845	COG0840	transmembrane signaling receptor activity
LV507_09860	COG0835	chemotaxis
LV507_09870	COG0840	transmembrane signaling receptor activity
LV507_09880	COG0840	transmembrane signaling receptor activity
LV507_09885	COG0840	transmembrane signaling receptor activity
LV507_09890	COG0840	transmembrane signaling receptor activity
LV507_09900	COG0840	transmembrane signaling receptor activity
LV507_09910	COG0840	transmembrane signaling receptor activity
LV507_09915	COG0840	transmembrane signaling receptor activity
LV507_09925	COG0840	transmembrane signaling receptor activity
LV507_09930	COG0840	transmembrane signaling receptor activity
LV507_09945	COG0745	RESPONSE REGULATOR receiver
LV507_09955	COG0835	chemotaxis
LV507_09960	COG1192	Involved in chromosome partitioning
LV507_09970	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
LV507_09975	COG2198	Histidine kinase
LV507_09975	COG0784	Response regulator, receiver
LV507_09975	COG0643	Histidine kinase
LV507_09980	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
LV507_10025	COG1684	flagellar biosynthetic protein fliR
LV507_10030	COG1987	bacterial-type flagellum assembly
LV507_10040	COG3190	flagellar
LV507_10090	COG1677	Flagellar hook-basal body complex protein FliE
LV507_10135	COG1028	Short-chain dehydrogenase reductase Sdr
LV507_10140	COG1028	Short-chain dehydrogenase reductase Sdr
LV507_10145	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LV507_10165	COG2201	protein-glutamate methylesterase activity
LV507_10170	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
LV507_10175	COG2197	response regulator
LV507_10195	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
LV507_10200	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LV507_10205	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LV507_10210	COG1256	bacterial-type flagellum assembly
LV507_10210	COG4786	Flagellar basal body rod
LV507_10210	COG1256	bacterial-type flagellum assembly
LV507_10210	COG4786	Flagellar basal body rod
LV507_10225	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
LV507_10240	COG1749	Flagellar hook protein flgE
LV507_10250	COG1558	bacterial-type flagellum-dependent cell motility
LV507_10260	COG0835	chemotaxis
LV507_10260	COG0784	Response regulator, receiver
LV507_10325	COG2915	High frequency lysogenization protein hflD homolog
LV507_10330	COG0482	sulfurtransferase activity
LV507_10350	COG0542	response to heat
LV507_10360	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
LV507_10370	COG0492	ferredoxin-NADP+ reductase activity
LV507_10375	COG1674	ftsk spoiiie
LV507_10395	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LV507_10400	COG0038	chloride channel
LV507_10455	COG1595	DNA-templated transcription, initiation
LV507_10475	COG3038	cytochrome b561
LV507_10505	COG2244	polysaccharide biosynthetic process
LV507_10525	COG4106	trans-aconitate 2-methyltransferase activity
LV507_10545	COG0438	transferase activity, transferring glycosyl groups
LV507_10550	COG0438	transferase activity, transferring glycosyl groups
LV507_10570	COG1132	(ABC) transporter
LV507_10600	COG2801	Transposase and inactivated derivatives
LV507_10605	COG1022	Amp-dependent synthetase and ligase
LV507_10645	COG0512	Glutamine amidotransferase of anthranilate synthase
LV507_10665	COG2801	Transposase and inactivated derivatives
LV507_10690	COG1530	ribonuclease E activity
LV507_10705	COG0428	transporter
LV507_10720	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
LV507_10720	COG0316	Belongs to the HesB IscA family
LV507_10740	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LV507_10760	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LV507_10765	COG2957	Belongs to the agmatine deiminase family
LV507_10775	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LV507_10780	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
LV507_10785	COG0539	negative regulation of cytoplasmic translation
LV507_10790	COG0776	regulation of translation
LV507_10800	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
LV507_10805	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LV507_10815	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LV507_10820	COG0183	Belongs to the thiolase family
LV507_10825	COG1024	Enoyl-CoA hydratase
LV507_10825	COG1250	3-hydroxyacyl-CoA dehydrogenase
LV507_10840	COG0820	rRNA (adenine-C2-)-methyltransferase activity
LV507_10850	COG1426	Protein conserved in bacteria
LV507_10860	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LV507_10870	COG0746	molybdenum cofactor guanylyltransferase activity
LV507_10880	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LV507_10885	COG0475	glutathione-regulated potassium exporter activity
LV507_10885	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LV507_10905	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LV507_10915	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LV507_10915	COG0519	Catalyzes the synthesis of GMP from XMP
LV507_10945	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LV507_10945	COG0519	Catalyzes the synthesis of GMP from XMP
LV507_10945	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LV507_10945	COG0519	Catalyzes the synthesis of GMP from XMP
LV507_11020	COG1487	ribonuclease activity
LV507_11025	COG4691	Plasmid stability protein
LV507_11075	COG1501	Belongs to the glycosyl hydrolase 31 family
LV507_11080	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
LV507_11090	COG1914	H( )-stimulated, divalent metal cation uptake system
LV507_11105	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
LV507_11110	COG0668	transmembrane transport
LV507_11120	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
LV507_11135	COG1028	Short-chain dehydrogenase reductase Sdr
LV507_11140	COG1183	phosphatidylcholine synthase activity
LV507_11150	COG3243	poly(R)-hydroxyalkanoic acid synthase
LV507_11170	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LV507_11170	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
LV507_11180	COG4191	Histidine kinase
LV507_11180	COG0784	Response regulator, receiver
LV507_11185	COG2183	response to ionizing radiation
LV507_11260	COG1649	PFAM Uncharacterised BCR, COG1649
LV507_11265	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LV507_11270	COG1304	FMN binding
LV507_11280	COG0346	lactoylglutathione lyase activity
LV507_11295	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LV507_11320	COG1024	Enoyl-CoA hydratase
LV507_11325	COG1024	Enoyl-CoA hydratase
LV507_11335	COG1024	Enoyl-CoA hydratase
LV507_11355	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
LV507_11445	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LV507_11455	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LV507_11460	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
LV507_11470	COG0505	Belongs to the CarA family
LV507_11480	COG2258	MOSC domain
LV507_11485	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LV507_11510	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LV507_11520	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LV507_11525	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
LV507_11700	COG3179	chitinase
LV507_11840	COG3209	COG3209 Rhs family protein
LV507_11875	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LV507_11890	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LV507_11900	COG1663	tetraacyldisaccharide 4'-kinase activity
LV507_11905	COG1132	(ABC) transporter
LV507_11915	COG0811	peptide transport
LV507_11935	COG4591	ABC-type transport system involved in lipoprotein release permease component
LV507_11945	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
LV507_11960	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
LV507_11965	COG2009	succinate dehydrogenase
LV507_11975	COG0354	folic acid binding
LV507_11980	COG3842	ATPase activity
LV507_11985	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LV507_12000	COG0129	dihydroxy-acid dehydratase activity
LV507_12015	COG0395	ABC-type sugar transport system, permease component
LV507_12050	COG2350	Protein conserved in bacteria
LV507_12055	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
LV507_12060	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LV507_12065	COG1187	pseudouridine synthase activity
LV507_12090	COG0436	Aminotransferase
LV507_12095	COG4133	protoheme IX ABC transporter activity
LV507_12145	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LV507_12150	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
LV507_12155	COG4988	ABC transporter
LV507_12165	COG1294	oxidase, subunit
LV507_12210	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LV507_12215	COG2137	regulation of response to DNA damage stimulus
LV507_12220	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LV507_12225	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LV507_12230	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
LV507_12235	COG1546	Belongs to the CinA family
LV507_12240	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LV507_12250	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LV507_12255	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LV507_12265	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LV507_12270	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
LV507_12275	COG1534	Rna-binding protein
LV507_12290	COG1238	metal cluster binding
LV507_12300	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
LV507_12315	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
LV507_12320	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
LV507_12325	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
LV507_12340	COG0504	CTP synthase activity
LV507_12360	COG0306	phosphate transporter
LV507_12370	COG1253	flavin adenine dinucleotide binding
LV507_12385	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LV507_12420	COG0069	glutamate synthase activity
LV507_12425	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
LV507_12435	COG1609	Transcriptional regulator
LV507_12440	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LV507_12440	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
LV507_12445	COG1105	Belongs to the carbohydrate kinase PfkB family
LV507_12450	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LV507_12450	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LV507_12480	COG0577	efflux transmembrane transporter activity
LV507_12480	COG1136	(ABC) transporter
LV507_12535	COG0583	DNA-binding transcription factor activity
LV507_12560	COG0077	Prephenate dehydratase
LV507_12560	COG1605	Chorismate mutase
LV507_12565	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
LV507_12570	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
LV507_12610	COG4221	oxidoreductase activity
LV507_12625	COG1228	amidohydrolase
LV507_12640	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
LV507_12675	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
LV507_12685	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
LV507_12695	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LV507_12730	COG0316	Belongs to the HesB IscA family
LV507_12800	COG0288	reversible hydration of carbon dioxide
LV507_12810	COG1289	transmembrane transporter activity
LV507_12815	COG3844	kynureninase activity
LV507_12825	COG2925	Exonuclease
LV507_12875	COG2902	Dehydrogenase
LV507_12885	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LV507_12890	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LV507_12895	COG1960	acyl-CoA dehydrogenase activity
LV507_12905	COG0646	methionine synthase
LV507_12905	COG1410	methionine synthase
LV507_12910	COG0646	methionine synthase
LV507_12910	COG1410	methionine synthase
LV507_12920	COG2755	lipolytic protein G-D-S-L family
LV507_12920	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
LV507_12930	COG2900	Belongs to the SlyX family
LV507_12945	COG0386	Belongs to the glutathione peroxidase family
LV507_12955	COG1725	Transcriptional regulator
LV507_12960	COG1131	(ABC) transporter
LV507_13000	COG2850	peptidyl-arginine hydroxylation
LV507_13035	COG4677	pectinesterase activity
LV507_13070	COG0402	S-adenosylhomocysteine deaminase activity
LV507_13075	COG3548	integral membrane protein
LV507_13085	COG1509	lysine 2,3-aminomutase activity
LV507_13090	COG4251	negative regulation of phosphorylation
LV507_13090	COG5001	Diguanylate cyclase
LV507_13090	COG2203	Gaf domain
LV507_13090	COG3706	GGDEF domain
LV507_13115	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LV507_13120	COG1862	Preprotein translocase
LV507_13130	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
LV507_13140	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LV507_13150	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LV507_13155	COG3291	Pkd domain containing protein
LV507_13160	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LV507_13165	COG0405	Gamma-glutamyltransferase
LV507_13170	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LV507_13185	COG0742	ribosomal rna small subunit methyltransferase
LV507_13210	COG4771	TonB-dependent receptor
LV507_13220	COG3507	Belongs to the glycosyl hydrolase 43 family
LV507_13260	COG0531	amino acid
LV507_13275	COG0006	proline dipeptidase activity
LV507_13285	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LV507_13300	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LV507_13305	COG3938	Belongs to the proline racemase family
LV507_13315	COG0552	protein localization to endoplasmic reticulum
LV507_13320	COG1194	a g-specific adenine glycosylase
LV507_13365	COG0835	chemotaxis
LV507_13370	COG0840	transmembrane signaling receptor activity
LV507_13375	COG0840	transmembrane signaling receptor activity
LV507_13390	COG5001	Diguanylate cyclase
LV507_13390	COG3300	MHYT domain
LV507_13395	COG1185	polyribonucleotide nucleotidyltransferase activity
LV507_13405	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LV507_13420	COG0195	Participates in both transcription termination and antitermination
LV507_13435	COG1007	ATP synthesis coupled electron transport
LV507_13475	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
LV507_13480	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
LV507_13485	COG0649	NAD binding
LV507_13490	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LV507_13500	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LV507_13530	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
LV507_13590	COG2890	protein-(glutamine-N5) methyltransferase activity
LV507_13600	COG0688	phosphatidylethanolamine metabolic process
LV507_13605	COG0741	lytic transglycosylase activity
LV507_13610	COG0433	COG0433 Predicted ATPase
LV507_13615	COG0494	nUDIX hydrolase
LV507_13630	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LV507_13650	COG1714	RDD family
LV507_13655	COG0717	Belongs to the dCTP deaminase family
LV507_13660	COG0489	protein tyrosine kinase activity
LV507_13670	COG4771	TonB-dependent receptor
LV507_13680	COG4771	TonB-dependent receptor
LV507_13685	COG0457	Tetratricopeptide repeat
LV507_13700	COG3590	peptidase
LV507_13740	COG0697	spore germination
LV507_13760	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LV507_13765	COG2311	Membrane
LV507_13770	COG1047	Peptidyl-prolyl cis-trans
LV507_13775	COG0791	NLP P60 protein
LV507_13780	COG0791	NLP P60 protein
LV507_13795	COG1607	acyl-coa hydrolase
LV507_13805	COG1301	dicarboxylic acid transport
LV507_13810	COG1785	Belongs to the alkaline phosphatase family
LV507_13820	COG0037	tRNA processing
LV507_13825	COG1722	exodeoxyribonuclease VII activity
LV507_13830	COG0142	geranyltranstransferase activity
LV507_13840	COG1858	cytochrome C peroxidase
LV507_13865	COG0515	serine threonine protein kinase
LV507_13865	COG2815	serine threonine protein kinase
LV507_13870	COG0631	protein serine/threonine phosphatase activity
LV507_13965	COG0312	modulator of DNA gyrase
LV507_13975	COG0312	modulator of DNA gyrase
LV507_13995	COG2968	Membrane
LV507_14010	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
LV507_14025	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LV507_14040	COG0495	leucyl-tRNA aminoacylation
LV507_14050	COG3118	belongs to the thioredoxin family
LV507_14065	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
LV507_14075	COG2040	homocysteine
LV507_14080	COG0833	amino acid
LV507_14090	COG0346	lactoylglutathione lyase activity
LV507_14110	COG2878	Part of a membrane complex involved in electron transport
LV507_14125	COG1595	DNA-templated transcription, initiation
LV507_14150	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LV507_14170	COG0251	oxidation-reduction process
LV507_14180	COG0392	lysyltransferase activity
LV507_14180	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LV507_14210	COG2814	Major facilitator Superfamily
LV507_14215	COG1902	pentaerythritol trinitrate reductase activity
LV507_14220	COG2824	Alkylphosphonate utilization operon protein PhnA
LV507_14225	COG1047	Peptidyl-prolyl cis-trans
LV507_14230	COG1077	Cell shape determining protein MreB Mrl
LV507_14265	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
LV507_14275	COG1451	nucleotide metabolic process
LV507_14295	COG0784	Response regulator, receiver
LV507_14295	COG2205	protein histidine kinase activity
LV507_14295	COG2198	Histidine kinase
LV507_14305	COG2186	Transcriptional regulator
LV507_14310	COG3250	beta-galactosidase activity
LV507_14375	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
LV507_14375	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
LV507_14375	COG1703	isobutyryl-CoA mutase activity
LV507_14405	COG0183	Belongs to the thiolase family
LV507_14415	COG0443	Heat shock 70 kDa protein
LV507_14445	COG1793	dna ligase
LV507_14445	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
LV507_14450	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
LV507_14450	COG1793	dna ligase
LV507_14455	COG1201	RNA secondary structure unwinding
LV507_14465	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LV507_14470	COG1278	Cold shock
LV507_14475	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
LV507_14480	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
LV507_14485	COG1472	Belongs to the glycosyl hydrolase 3 family
LV507_14495	COG2954	triphosphatase activity
LV507_14505	COG0745	RESPONSE REGULATOR receiver
LV507_14510	COG1381	Involved in DNA repair and RecF pathway recombination
LV507_14515	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LV507_14530	COG0681	Belongs to the peptidase S26 family
LV507_14535	COG0481	GTPase activity
LV507_14540	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LV507_14575	COG2855	membrane
LV507_14590	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LV507_14620	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
LV507_14630	COG0534	Mate efflux family protein
LV507_14635	COG0335	large ribosomal subunit rRNA binding
LV507_14640	COG0336	Belongs to the RNA methyltransferase TrmD family
LV507_14645	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LV507_14660	COG2070	2-Nitropropane dioxygenase
LV507_14665	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LV507_14690	COG0475	glutathione-regulated potassium exporter activity
LV507_14700	COG0625	glutathione transferase activity
LV507_14705	COG1082	Xylose isomerase domain protein TIM barrel
LV507_14715	COG1172	Belongs to the binding-protein-dependent transport system permease family
LV507_14720	COG1172	Belongs to the binding-protein-dependent transport system permease family
LV507_14725	COG1129	ABC transporter
LV507_14730	COG1879	ABC-type sugar transport system periplasmic component
LV507_14735	COG1012	belongs to the aldehyde dehydrogenase family
LV507_14755	COG0129	dihydroxy-acid dehydratase activity
LV507_14785	COG2207	Transcriptional regulator
LV507_14835	COG1129	ABC transporter
LV507_14845	COG1879	ABC-type sugar transport system periplasmic component
LV507_14850	COG1012	belongs to the aldehyde dehydrogenase family
LV507_14870	COG0129	dihydroxy-acid dehydratase activity
LV507_14900	COG2207	Transcriptional regulator
LV507_14945	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LV507_14970	COG4794	Type iii secretion
LV507_15000	COG0745	RESPONSE REGULATOR receiver
LV507_15055	COG0156	8-amino-7-oxononanoate synthase activity
LV507_15065	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
LV507_15070	COG1845	cytochrome c oxidase, subunit III
LV507_15075	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LV507_15105	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
LV507_15135	COG0728	peptidoglycan biosynthetic process
LV507_15145	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LV507_15150	COG0211	Belongs to the bacterial ribosomal protein bL27 family
LV507_15155	COG0261	This protein binds to 23S rRNA in the presence of protein L20
LV507_15160	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LV507_15175	COG1024	Enoyl-CoA hydratase
LV507_15180	COG1946	Acyl-CoA thioesterase
LV507_15260	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LV507_15305	COG1643	Atp-dependent helicase
LV507_15310	COG0783	Belongs to the Dps family
LV507_15315	COG0514	ATP-dependent DNA helicase (RecQ)
LV507_15335	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
LV507_15340	COG0602	queuosine metabolic process
LV507_15350	COG2885	chlorophyll binding
LV507_15365	COG0848	biopolymer transport protein
LV507_15375	COG0824	Thioesterase
LV507_15380	COG2255	four-way junction helicase activity
LV507_15385	COG3158	transport of potassium into the cell
LV507_15390	COG0632	four-way junction helicase activity
LV507_15400	COG0217	transcriptional regulatory protein
LV507_15440	COG3142	Participates in the control of copper homeostasis
LV507_15445	COG1446	asparaginase
LV507_15475	COG2201	protein-glutamate methylesterase activity
LV507_15480	COG2198	Histidine kinase
LV507_15480	COG0643	Histidine kinase
LV507_15480	COG0784	Response regulator, receiver
LV507_15485	COG0840	transmembrane signaling receptor activity
LV507_15490	COG0835	chemotaxis
LV507_15505	COG0189	ligase activity
LV507_15530	COG1199	ATP-dependent helicase activity
LV507_15540	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LV507_15545	COG1216	Glycosyl transferase, family 2
LV507_15555	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
LV507_15575	COG4585	Histidine kinase
LV507_15585	COG0850	regulation of cytokinetic process
LV507_15590	COG2894	cell division
LV507_15595	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
LV507_15605	COG2205	protein histidine kinase activity
LV507_15610	COG0745	RESPONSE REGULATOR receiver
LV507_15620	COG2194	sulfuric ester hydrolase activity
LV507_15655	COG2814	Major facilitator Superfamily
LV507_15680	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LV507_15680	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LV507_15695	COG0753	catalase activity
LV507_15720	COG1063	alcohol dehydrogenase
LV507_15730	COG3459	Glycosyltransferase 36 associated
LV507_15860	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LV507_15870	COG0330	HflC and HflK could
LV507_15875	COG0330	HflC and HflK could
LV507_15880	COG0604	alcohol dehydrogenase
LV507_15900	COG0678	peroxiredoxin activity
LV507_15930	COG2373	Large extracellular alpha-helical protein
LV507_15980	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
LV507_15995	COG0372	Belongs to the citrate synthase family
LV507_16020	COG2161	toxin-antitoxin pair type II binding
LV507_16025	COG4115	mRNA cleavage
LV507_16045	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LV507_16050	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LV507_16055	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LV507_16065	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LV507_16070	COG1028	Short-chain dehydrogenase reductase Sdr
LV507_16075	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
LV507_16080	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LV507_16090	COG1399	metal-binding, possibly nucleic acid-binding protein
LV507_16115	COG0714	Associated with various cellular activities
LV507_16135	COG0537	adenosine 5'-monophosphoramidase activity
LV507_16180	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LV507_16190	COG1940	carbohydrate kinase activity
LV507_16205	COG0671	phosphoesterase, PA-phosphatase related
LV507_16215	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LV507_16240	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
LV507_16250	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
LV507_16275	COG0840	transmembrane signaling receptor activity
LV507_16280	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
LV507_16300	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LV507_16320	COG0066	3-isopropylmalate dehydratase activity
LV507_16325	COG0473	3-isopropylmalate dehydrogenase activity
LV507_16330	COG3706	GGDEF domain
LV507_16335	COG1309	transcriptional regulator
LV507_16340	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
LV507_16345	COG1538	Outer membrane efflux protein
LV507_16350	COG1519	Transferase
LV507_16355	COG1560	Kdo2-lipid A biosynthetic process
LV507_16425	COG0280	phosphate acetyltransferase
LV507_16425	COG0281	malic enzyme
LV507_16430	COG1301	dicarboxylic acid transport
LV507_16440	COG4191	Histidine kinase
LV507_16460	COG0642	Histidine kinase
LV507_16475	COG2851	Citrate transporter
LV507_16480	COG1028	Short-chain dehydrogenase reductase Sdr
LV507_16490	COG2211	Major facilitator Superfamily
LV507_16515	COG1162	GTPase activity
LV507_16595	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
LV507_16615	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LV507_16620	COG0804	urea catabolic process
LV507_16660	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LV507_16670	COG3791	Glutathione-dependent formaldehyde-activating
LV507_16675	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
LV507_16690	COG2205	protein histidine kinase activity
LV507_16740	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LV507_16765	COG0617	tRNA 3'-terminal CCA addition
LV507_16775	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LV507_16780	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LV507_16785	COG1609	Transcriptional regulator
LV507_16790	COG0738	Major facilitator superfamily
LV507_16795	COG2188	Transcriptional regulator
LV507_16810	COG3250	beta-galactosidase activity
LV507_16830	COG4305	rare lipoprotein A
LV507_16845	COG1028	Short-chain dehydrogenase reductase Sdr
LV507_16850	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LV507_16860	COG4191	Histidine kinase
LV507_16865	COG0784	Response regulator, receiver
LV507_16870	COG2202	Pas domain
LV507_16870	COG2205	protein histidine kinase activity
LV507_16880	COG2823	Periplasmic or secreted lipoprotein
LV507_16885	COG0673	inositol 2-dehydrogenase activity
LV507_16890	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
LV507_16900	COG1090	epimerase
LV507_16920	COG1051	belongs to the nudix hydrolase family
LV507_16920	COG1056	cytidyltransferase-related domain
LV507_16945	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LV507_16950	COG0321	lipoyl(octanoyl) transferase activity
LV507_16980	COG1686	Belongs to the peptidase S11 family
LV507_16990	COG2951	lytic endotransglycosylase activity
LV507_17010	COG0772	Belongs to the SEDS family
LV507_17015	COG0768	penicillin binding
LV507_17030	COG1077	Cell shape determining protein MreB Mrl
LV507_17035	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LV507_17040	COG3284	Transcriptional regulator
LV507_17050	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
LV507_17060	COG2010	Cytochrome c
LV507_17085	COG0596	Alpha beta hydrolase
LV507_17085	COG0508	dehydrogenase complex catalyzes the overall conversion of
LV507_17090	COG0308	aminopeptidase N
LV507_17095	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LV507_17105	COG2226	methyltransferase
LV507_17150	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
LV507_17160	COG2832	Protein of unknown function (DUF454)
LV507_17170	COG0436	Aminotransferase
LV507_17175	COG1505	serine-type exopeptidase activity
LV507_17190	COG1733	regulation of RNA biosynthetic process
LV507_17210	COG0181	hydroxymethylbilane synthase activity
LV507_17235	COG0745	RESPONSE REGULATOR receiver
LV507_17255	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LV507_17260	COG1640	4-alpha-glucanotransferase
LV507_17285	COG0243	molybdopterin cofactor binding
LV507_17290	COG2146	nitrite reductase [NAD(P)H] activity
LV507_17295	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LV507_17300	COG2223	nitrite transmembrane transporter activity
LV507_17305	COG1116	anion transmembrane transporter activity
LV507_17305	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LV507_17335	COG3645	SOS response
LV507_17345	COG0732	type I restriction modification DNA specificity domain
LV507_17350	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
LV507_17380	COG2204	response regulator
LV507_17385	COG4191	Histidine kinase
LV507_17390	COG0028	Belongs to the TPP enzyme family
LV507_17405	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LV507_17420	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
LV507_17430	COG1028	Short-chain dehydrogenase reductase Sdr
LV507_17440	COG3685	Protein conserved in bacteria
LV507_17445	COG3685	Protein conserved in bacteria
LV507_17455	COG0840	transmembrane signaling receptor activity
LV507_17500	COG1309	transcriptional regulator
LV507_17555	COG0366	Alpha amylase catalytic
LV507_17560	COG0366	Alpha amylase catalytic
LV507_17570	COG1609	Transcriptional regulator
LV507_17605	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LV507_17610	COG1490	D-aminoacyl-tRNA deacylase activity
LV507_17625	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LV507_17650	COG3307	-O-antigen
LV507_17660	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LV507_17665	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LV507_17665	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LV507_17670	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LV507_17675	COG0242	peptide deformylase activity
LV507_17680	COG1652	LysM domain
LV507_17685	COG0758	DNA mediated transformation
LV507_17700	COG1714	RDD family
LV507_17705	COG1754	DNA topoisomerase type I activity
LV507_17705	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LV507_17710	COG0009	L-threonylcarbamoyladenylate synthase
LV507_17730	COG1028	Short-chain dehydrogenase reductase Sdr
LV507_17740	COG0616	signal peptide processing
LV507_17745	COG0534	Mate efflux family protein
LV507_17755	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LV507_17765	COG1252	NADH dehydrogenase
LV507_17775	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LV507_17780	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
LV507_17785	COG2201	protein-glutamate methylesterase activity
LV507_17790	COG2177	Part of the ABC transporter FtsEX involved in
LV507_17795	COG2884	Cell division ATP-binding protein ftsE
LV507_17805	COG3118	belongs to the thioredoxin family
LV507_17810	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
LV507_17840	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
LV507_17885	COG1518	maintenance of DNA repeat elements
LV507_17890	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
LV507_17900	COG1652	LysM domain
LV507_17915	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LV507_17920	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LV507_17925	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LV507_17935	COG5383	Protein conserved in bacteria
LV507_17975	COG3501	Rhs element vgr protein
LV507_17975	COG3409	Peptidoglycan-binding domain 1 protein
LV507_17995	COG4771	TonB-dependent receptor
LV507_18005	COG4948	Mandelate Racemase Muconate Lactonizing
LV507_18015	COG0531	amino acid
LV507_18035	COG2133	pyrroloquinoline quinone binding
LV507_18050	COG2308	Evidence 4 Homologs of previously reported genes of
LV507_18070	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LV507_18090	COG1295	ribonuclease BN
LV507_18095	COG0358	DNA primase activity
LV507_18110	COG0109	protoheme IX farnesyltransferase activity
LV507_18140	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
LV507_18145	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LV507_18150	COG1565	acr, cog1565
LV507_18150	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LV507_18165	COG1486	melibiose metabolic process
LV507_18210	COG0793	Belongs to the peptidase S41A family
LV507_18215	COG4942	peptidase
LV507_18225	COG2234	aminopeptidase activity
LV507_18230	COG1064	alcohol dehydrogenase
LV507_18260	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LV507_18265	COG0739	heme binding
LV507_18270	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
LV507_18280	COG2814	Major facilitator Superfamily
LV507_18290	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LV507_18310	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LV507_18330	COG4221	oxidoreductase activity
LV507_18355	COG0583	DNA-binding transcription factor activity
LV507_18360	COG2755	lipolytic protein G-D-S-L family
LV507_18360	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
LV507_18365	COG1819	glycosyl
LV507_18370	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LV507_18375	COG1166	arginine decarboxylase activity
LV507_18390	COG2960	long-chain fatty acid transporting porin activity
LV507_18395	COG0606	chelatase, subunit chli
LV507_18425	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LV507_18435	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
LV507_18450	COG1028	Short-chain dehydrogenase reductase Sdr
LV507_18470	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LV507_18485	COG2203	Gaf domain
LV507_18485	COG3706	GGDEF domain
LV507_18485	COG4251	negative regulation of phosphorylation
LV507_18485	COG5001	Diguanylate cyclase
LV507_18495	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LV507_18500	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LV507_18515	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LV507_18530	COG1522	sequence-specific DNA binding
LV507_18565	COG0714	Associated with various cellular activities
LV507_18575	COG0754	glutathionylspermidine amidase activity
LV507_18660	COG2133	pyrroloquinoline quinone binding
LV507_18670	COG0628	permease
LV507_18690	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LV507_18755	COG1199	ATP-dependent helicase activity
LV507_18815	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
LV507_18840	COG3104	oligopeptide transport
LV507_18860	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
LV507_18875	COG0508	dehydrogenase complex catalyzes the overall conversion of
LV507_18890	COG3227	Zinc metalloprotease (Elastase)
LV507_18895	COG0513	Belongs to the DEAD box helicase family
LV507_18925	COG2354	Protein conserved in bacteria
LV507_18945	COG1196	nuclear chromosome segregation
LV507_18945	COG3264	Mechanosensitive ion channel
LV507_18950	COG1028	Short-chain dehydrogenase reductase Sdr
LV507_18950	COG3321	synthase
LV507_18950	COG0604	alcohol dehydrogenase
LV507_18970	COG1595	DNA-templated transcription, initiation
LV507_18990	COG0477	Major facilitator Superfamily
LV507_18995	COG1802	Transcriptional regulator
LV507_19040	COG1414	Transcriptional regulator
LV507_19045	COG0738	Major facilitator superfamily
LV507_19050	COG3254	rhamnose metabolic process
LV507_19055	COG4948	Mandelate Racemase Muconate Lactonizing
LV507_19060	COG0179	Fumarylacetoacetate (FAA) hydrolase
LV507_19065	COG1028	Short-chain dehydrogenase reductase Sdr
LV507_19095	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LV507_19110	COG4807	Protein conserved in bacteria
LV507_19130	COG4773	Receptor
LV507_19145	COG1506	peptidase
LV507_19145	COG0823	Involved in the tonB-independent uptake of proteins
LV507_19240	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LV507_19265	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LV507_19270	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LV507_19275	COG0753	catalase activity
LV507_19300	COG1136	(ABC) transporter
LV507_19305	COG0577	efflux transmembrane transporter activity
LV507_19325	COG0697	spore germination
LV507_19340	COG0180	Tryptophanyl-tRNA synthetase
LV507_19375	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
LV507_19380	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
LV507_19380	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
LV507_19390	COG3228	Belongs to the MtfA family
LV507_19420	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LV507_19445	COG2084	Dehydrogenase
LV507_19450	COG1902	pentaerythritol trinitrate reductase activity
LV507_19460	COG2814	Major facilitator Superfamily
LV507_19465	COG0583	DNA-binding transcription factor activity
LV507_19495	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LV507_19500	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LV507_19505	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
LV507_19510	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
LV507_19515	COG1764	response to oxidative stress
LV507_19520	COG1846	Transcriptional regulator
LV507_19525	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
LV507_19535	COG0697	spore germination
LV507_19540	COG0523	cobalamin synthesis protein
LV507_19550	COG1742	UPF0060 membrane protein
LV507_19560	COG3245	cytochrome
LV507_19570	COG1960	acyl-CoA dehydrogenase activity
LV507_19575	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LV507_19590	COG1278	Cold shock
LV507_19605	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LV507_19610	COG3387	PFAM Glycoside hydrolase 15-related
LV507_19615	COG0745	RESPONSE REGULATOR receiver
LV507_19630	COG1404	Belongs to the peptidase S8 family
LV507_19640	COG3100	YcgL domain-containing protein
LV507_19645	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LV507_19655	COG0463	Glycosyl transferase, family 2
LV507_19690	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LV507_19705	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LV507_19730	COG1294	oxidase, subunit
LV507_19735	COG1271	oxidase subunit
LV507_19755	COG0408	coproporphyrinogen oxidase activity
LV507_19765	COG2323	membrane
LV507_19770	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LV507_19770	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LV507_19790	COG0589	response to stress
LV507_19815	COG0210	DNA helicase
LV507_19865	COG0463	Glycosyl transferase, family 2
LV507_19875	COG1475	DNA binding
LV507_19880	COG1192	Involved in chromosome partitioning
LV507_19885	COG0357	Ribosomal RNA small subunit methyltransferase G
LV507_19895	COG2091	lysine biosynthetic process via aminoadipic acid
LV507_19920	COG0477	Major facilitator Superfamily
LV507_19940	COG1971	Probably functions as a manganese efflux pump
LV507_19945	COG2205	protein histidine kinase activity
LV507_19955	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LV507_19960	COG3459	Glycosyltransferase 36 associated
LV507_19965	COG2211	Major facilitator Superfamily
LV507_19970	COG3265	gluconokinase activity
LV507_19985	COG2911	Protein conserved in bacteria
LV507_19990	COG0729	surface antigen
LV507_20010	COG3132	Protein of unknown function, DUF480
LV507_20050	COG0284	orotidine-5'-phosphate decarboxylase activity
LV507_20065	COG1609	Transcriptional regulator
LV507_20075	COG2937	Belongs to the GPAT DAPAT family
LV507_20100	COG2211	Major facilitator Superfamily
LV507_20115	COG3693	PFAM glycoside hydrolase, family 10
LV507_20120	COG1904	glucuronate isomerase
LV507_20135	COG3386	PFAM SMP-30 Gluconolaconase
LV507_20145	COG3046	protein related to deoxyribodipyrimidine photolyase
LV507_20160	COG0246	Mannitol dehydrogenase
LV507_20165	COG1472	Belongs to the glycosyl hydrolase 3 family
LV507_20175	COG4948	Mandelate Racemase Muconate Lactonizing
LV507_20185	COG3661	Belongs to the glycosyl hydrolase 67 family
LV507_20195	COG2115	Belongs to the xylose isomerase family
LV507_20200	COG0037	tRNA processing
LV507_20220	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
LV507_20230	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LV507_20240	COG0805	protein transport
LV507_20250	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LV507_20250	COG0519	Catalyzes the synthesis of GMP from XMP
LV507_20255	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LV507_20275	COG0210	DNA helicase
LV507_20280	COG1435	thymidine kinase activity
LV507_20290	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
LV507_20305	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LV507_20320	COG1119	ATPase activity
LV507_20335	COG0706	membrane insertase activity
LV507_20340	COG0594	ribonuclease P activity