locus-tag	class	description
KCU57_00010	COG0592	DNA-directed DNA polymerase activity
KCU57_00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KCU57_00020	COG0187	DNA topoisomerase II activity
KCU57_00025	COG1266	CAAX protease self-immunity
KCU57_00030	COG0501	Belongs to the peptidase M48B family
KCU57_00060	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
KCU57_00070	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KCU57_00100	COG4772	TonB-dependent receptor
KCU57_00110	COG3284	Transcriptional regulator
KCU57_00115	COG1012	belongs to the aldehyde dehydrogenase family
KCU57_00150	COG1304	FMN binding
KCU57_00155	COG2186	Transcriptional regulator
KCU57_00175	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KCU57_00255	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KCU57_00275	COG4771	TonB-dependent receptor
KCU57_00320	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
KCU57_00335	COG3507	Belongs to the glycosyl hydrolase 43 family
KCU57_00340	COG1609	Transcriptional regulator
KCU57_00350	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
KCU57_00355	COG1028	Short-chain dehydrogenase reductase Sdr
KCU57_00370	COG3186	Phenylalanine-4-hydroxylase
KCU57_00375	COG1522	sequence-specific DNA binding
KCU57_00430	COG1752	Esterase of the alpha-beta hydrolase superfamily
KCU57_00445	COG0671	phosphoesterase, PA-phosphatase related
KCU57_00460	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KCU57_00490	COG1929	Belongs to the glycerate kinase type-1 family
KCU57_00505	COG4566	intracellular signal transduction
KCU57_00510	COG4191	Histidine kinase
KCU57_00530	COG1322	Protein conserved in bacteria
KCU57_00535	COG0386	Belongs to the glutathione peroxidase family
KCU57_00540	COG2853	Lipoprotein
KCU57_00555	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
KCU57_00560	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
KCU57_00565	COG1127	ABC transporter
KCU57_00570	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
KCU57_00575	COG1074	ATP-dependent DNA helicase activity
KCU57_00580	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KCU57_00600	COG0537	adenosine 5'-monophosphoramidase activity
KCU57_00705	COG0477	Major facilitator Superfamily
KCU57_00710	COG0302	gtp cyclohydrolase
KCU57_00715	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KCU57_00745	COG0730	response to heat
KCU57_00760	COG2951	lytic endotransglycosylase activity
KCU57_00820	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
KCU57_00825	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
KCU57_00830	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
KCU57_00835	COG0493	'glutamate synthase
KCU57_00840	COG0070	glutamate synthase
KCU57_00840	COG0067	glutamate synthase
KCU57_00840	COG0069	glutamate synthase activity
KCU57_00880	COG1205	dead DEAH box helicase
KCU57_00880	COG1111	helicase
KCU57_00910	COG2271	Major facilitator Superfamily
KCU57_00960	COG2062	phosphohistidine phosphatase, SixA
KCU57_00970	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KCU57_00975	COG2050	protein possibly involved in aromatic compounds catabolism
KCU57_00985	COG2267	carboxylic ester hydrolase activity
KCU57_00995	COG1881	PFAM PEBP family protein
KCU57_01000	COG1968	undecaprenyl-diphosphatase activity
KCU57_01005	COG0174	glutamine synthetase
KCU57_01010	COG0347	Belongs to the P(II) protein family
KCU57_01015	COG0004	ammonium transporteR
KCU57_01020	COG3852	Histidine kinase
KCU57_01025	COG2204	response regulator
KCU57_01030	COG2032	superoxide dismutase activity
KCU57_01035	COG2032	superoxide dismutase activity
KCU57_01045	COG0183	Belongs to the thiolase family
KCU57_01085	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
KCU57_01090	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
KCU57_01100	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KCU57_01110	COG0612	Peptidase, M16
KCU57_01120	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KCU57_01125	COG3177	Filamentation induced by cAMP protein fic
KCU57_01140	COG0596	Alpha beta hydrolase
KCU57_01150	COG0727	PFAM Uncharacterised protein family (UPF0153)
KCU57_01155	COG0318	PFAM AMP-dependent synthetase and ligase
KCU57_01170	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KCU57_01180	COG1181	Belongs to the D-alanine--D-alanine ligase family
KCU57_01195	COG4232	protein-disulfide reductase activity
KCU57_01200	COG0564	pseudouridine synthase activity
KCU57_01220	COG0339	signal peptide processing
KCU57_01240	COG0583	DNA-binding transcription factor activity
KCU57_01245	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
KCU57_01250	COG2224	Isocitrate lyase
KCU57_01285	COG0659	secondary active sulfate transmembrane transporter activity
KCU57_01315	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KCU57_01320	COG2130	NADP-dependent
KCU57_01335	COG1187	pseudouridine synthase activity
KCU57_01345	COG1643	Atp-dependent helicase
KCU57_01350	COG0084	hydrolase, TatD family'
KCU57_01440	COG0842	Transport permease protein
KCU57_01445	COG1131	(ABC) transporter
KCU57_01450	COG0543	2 iron, 2 sulfur cluster binding
KCU57_01450	COG0633	Ferredoxin
KCU57_01460	COG1476	TRANSCRIPTIONal
KCU57_01470	COG4555	ABC transporter
KCU57_01490	COG0625	glutathione transferase activity
KCU57_01560	COG1199	ATP-dependent helicase activity
KCU57_01615	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KCU57_01635	COG0628	permease
KCU57_01645	COG2133	pyrroloquinoline quinone binding
KCU57_01685	COG0754	glutathionylspermidine amidase activity
KCU57_01695	COG0714	Associated with various cellular activities
KCU57_01730	COG1522	sequence-specific DNA binding
KCU57_01745	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KCU57_01755	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KCU57_01760	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KCU57_01785	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KCU57_01805	COG1028	Short-chain dehydrogenase reductase Sdr
KCU57_01820	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
KCU57_01830	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KCU57_01845	COG0582	viral genome integration into host DNA
KCU57_01910	COG0484	heat shock protein binding
KCU57_01920	COG2003	Belongs to the UPF0758 family
KCU57_01995	COG0606	chelatase, subunit chli
KCU57_02000	COG2960	long-chain fatty acid transporting porin activity
KCU57_02020	COG1166	arginine decarboxylase activity
KCU57_02030	COG1819	glycosyl
KCU57_02035	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
KCU57_02035	COG2755	lipolytic protein G-D-S-L family
KCU57_02040	COG0583	DNA-binding transcription factor activity
KCU57_02060	COG4221	oxidoreductase activity
KCU57_02080	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KCU57_02100	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KCU57_02110	COG2814	Major facilitator Superfamily
KCU57_02120	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
KCU57_02125	COG0739	heme binding
KCU57_02130	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KCU57_02160	COG1064	alcohol dehydrogenase
KCU57_02165	COG2234	aminopeptidase activity
KCU57_02175	COG4942	peptidase
KCU57_02180	COG0793	Belongs to the peptidase S41A family
KCU57_02220	COG0531	amino acid
KCU57_02225	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
KCU57_02225	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
KCU57_02230	COG1486	melibiose metabolic process
KCU57_02245	COG1565	acr, cog1565
KCU57_02245	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KCU57_02250	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KCU57_02255	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
KCU57_02290	COG0109	protoheme IX farnesyltransferase activity
KCU57_02305	COG0358	DNA primase activity
KCU57_02310	COG1295	ribonuclease BN
KCU57_02330	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KCU57_02355	COG2308	Evidence 4 Homologs of previously reported genes of
KCU57_02370	COG2133	pyrroloquinoline quinone binding
KCU57_02390	COG0531	amino acid
KCU57_02400	COG4948	Mandelate Racemase Muconate Lactonizing
KCU57_02410	COG4771	TonB-dependent receptor
KCU57_02440	COG3409	Peptidoglycan-binding domain 1 protein
KCU57_02440	COG3501	Rhs element vgr protein
KCU57_02475	COG5383	Protein conserved in bacteria
KCU57_02490	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KCU57_02495	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KCU57_02510	COG1652	LysM domain
KCU57_02520	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KCU57_02525	COG1518	maintenance of DNA repeat elements
KCU57_02580	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KCU57_02600	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KCU57_02605	COG3118	belongs to the thioredoxin family
KCU57_02615	COG2884	Cell division ATP-binding protein ftsE
KCU57_02620	COG2177	Part of the ABC transporter FtsEX involved in
KCU57_02625	COG2201	protein-glutamate methylesterase activity
KCU57_02630	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KCU57_02635	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KCU57_02640	COG2860	membrane
KCU57_02645	COG1252	NADH dehydrogenase
KCU57_02655	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KCU57_02665	COG0534	Mate efflux family protein
KCU57_02670	COG0616	signal peptide processing
KCU57_02680	COG1028	Short-chain dehydrogenase reductase Sdr
KCU57_02695	COG0009	L-threonylcarbamoyladenylate synthase
KCU57_02700	COG1754	DNA topoisomerase type I activity
KCU57_02700	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KCU57_02705	COG1714	RDD family
KCU57_02720	COG0758	DNA mediated transformation
KCU57_02725	COG1652	LysM domain
KCU57_02730	COG0242	peptide deformylase activity
KCU57_02735	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KCU57_02740	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KCU57_02740	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KCU57_02745	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KCU57_02755	COG3307	-O-antigen
KCU57_02780	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KCU57_02795	COG1490	D-aminoacyl-tRNA deacylase activity
KCU57_02800	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KCU57_02830	COG1609	Transcriptional regulator
KCU57_02840	COG0366	Alpha amylase catalytic
KCU57_02845	COG0366	Alpha amylase catalytic
KCU57_02885	COG0596	Alpha beta hydrolase
KCU57_02900	COG1309	transcriptional regulator
KCU57_02940	COG0840	transmembrane signaling receptor activity
KCU57_02955	COG3546	catalase activity
KCU57_02960	COG3685	Protein conserved in bacteria
KCU57_02965	COG3685	Protein conserved in bacteria
KCU57_02970	COG1028	Short-chain dehydrogenase reductase Sdr
KCU57_02980	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
KCU57_02995	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KCU57_03010	COG0028	Belongs to the TPP enzyme family
KCU57_03015	COG4191	Histidine kinase
KCU57_03020	COG2204	response regulator
KCU57_03045	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
KCU57_03065	COG3645	SOS response
KCU57_03095	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KCU57_03095	COG1116	anion transmembrane transporter activity
KCU57_03100	COG2223	nitrite transmembrane transporter activity
KCU57_03105	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KCU57_03110	COG2146	nitrite reductase [NAD(P)H] activity
KCU57_03115	COG0243	molybdopterin cofactor binding
KCU57_03140	COG1640	4-alpha-glucanotransferase
KCU57_03145	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KCU57_03190	COG0181	hydroxymethylbilane synthase activity
KCU57_03205	COG1733	regulation of RNA biosynthetic process
KCU57_03220	COG1505	serine-type exopeptidase activity
KCU57_03225	COG0436	Aminotransferase
KCU57_03235	COG2832	Protein of unknown function (DUF454)
KCU57_03245	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KCU57_03265	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
KCU57_03290	COG2226	methyltransferase
KCU57_03300	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KCU57_03305	COG0308	aminopeptidase N
KCU57_03310	COG0508	dehydrogenase complex catalyzes the overall conversion of
KCU57_03310	COG0596	Alpha beta hydrolase
KCU57_03335	COG2010	Cytochrome c
KCU57_03345	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
KCU57_03360	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KCU57_03365	COG1077	Cell shape determining protein MreB Mrl
KCU57_03370	COG1792	Involved in formation and maintenance of cell shape
KCU57_03380	COG0768	penicillin binding
KCU57_03385	COG0772	Belongs to the SEDS family
KCU57_03400	COG2951	lytic endotransglycosylase activity
KCU57_03410	COG1686	Belongs to the peptidase S11 family
KCU57_03475	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KCU57_03505	COG1051	belongs to the nudix hydrolase family
KCU57_03505	COG1056	cytidyltransferase-related domain
KCU57_03525	COG1090	epimerase
KCU57_03535	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
KCU57_03540	COG0673	inositol 2-dehydrogenase activity
KCU57_03545	COG2823	Periplasmic or secreted lipoprotein
KCU57_03555	COG2202	Pas domain
KCU57_03555	COG2205	protein histidine kinase activity
KCU57_03560	COG0784	Response regulator, receiver
KCU57_03565	COG4191	Histidine kinase
KCU57_03575	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KCU57_03580	COG1028	Short-chain dehydrogenase reductase Sdr
KCU57_03595	COG4305	rare lipoprotein A
KCU57_03605	COG3250	beta-galactosidase activity
KCU57_03620	COG2188	Transcriptional regulator
KCU57_03625	COG0738	Major facilitator superfamily
KCU57_03630	COG1609	Transcriptional regulator
KCU57_03635	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KCU57_03640	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KCU57_03650	COG0617	tRNA 3'-terminal CCA addition
KCU57_03670	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KCU57_03695	COG2207	Transcriptional regulator
KCU57_03720	COG2205	protein histidine kinase activity
KCU57_03735	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
KCU57_03740	COG3791	Glutathione-dependent formaldehyde-activating
KCU57_03770	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KCU57_03815	COG0804	urea catabolic process
KCU57_03820	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
KCU57_03840	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
KCU57_03890	COG1162	GTPase activity
KCU57_03915	COG2211	Major facilitator Superfamily
KCU57_03925	COG1028	Short-chain dehydrogenase reductase Sdr
KCU57_03930	COG2851	Citrate transporter
KCU57_03945	COG0642	Histidine kinase
KCU57_03980	COG4191	Histidine kinase
KCU57_03990	COG1301	dicarboxylic acid transport
KCU57_03995	COG0281	malic enzyme
KCU57_03995	COG0280	phosphate acetyltransferase
KCU57_04060	COG1560	Kdo2-lipid A biosynthetic process
KCU57_04065	COG1519	Transferase
KCU57_04070	COG1538	Outer membrane efflux protein
KCU57_04075	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
KCU57_04085	COG3706	GGDEF domain
KCU57_04090	COG0473	3-isopropylmalate dehydrogenase activity
KCU57_04095	COG0066	3-isopropylmalate dehydratase activity
KCU57_04115	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KCU57_04140	COG0840	transmembrane signaling receptor activity
KCU57_04160	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
KCU57_04170	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
KCU57_04190	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KCU57_04200	COG0671	phosphoesterase, PA-phosphatase related
KCU57_04215	COG1940	carbohydrate kinase activity
KCU57_04225	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KCU57_04235	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
KCU57_04250	COG1773	rubredoxin
KCU57_04270	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KCU57_04280	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KCU57_04305	COG3079	Belongs to the UPF0149 family
KCU57_04310	COG0006	proline dipeptidase activity
KCU57_04315	COG0006	proline dipeptidase activity
KCU57_04330	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KCU57_04335	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KCU57_04340	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
KCU57_04345	COG1561	YicC-like family, N-terminal region
KCU57_04350	COG0194	GDP metabolic process
KCU57_04355	COG1758	RNA polymerase activity
KCU57_04360	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KCU57_04385	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KCU57_04395	COG0254	rRNA binding
KCU57_04400	COG0372	Belongs to the citrate synthase family
KCU57_04415	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
KCU57_04445	COG0714	Associated with various cellular activities
KCU57_04475	COG1301	dicarboxylic acid transport
KCU57_04480	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KCU57_04510	COG0739	heme binding
KCU57_04515	COG1376	ErfK ybiS ycfS ynhG family protein
KCU57_04540	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
KCU57_04545	COG4149	molybdate abc transporter
KCU57_04550	COG0725	ABC transporter, periplasmic molybdate-binding protein
KCU57_04560	COG0640	Transcriptional regulator
KCU57_04580	COG3047	cAMP biosynthetic process
KCU57_04585	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KCU57_04630	COG0469	pyruvate kinase activity
KCU57_04635	COG3588	fructose-bisphosphate aldolase
KCU57_04640	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
KCU57_04680	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KCU57_04695	COG1648	precorrin-2 dehydrogenase activity
KCU57_04695	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KCU57_04710	COG2205	protein histidine kinase activity
KCU57_04710	COG2198	Histidine kinase
KCU57_04710	COG0784	Response regulator, receiver
KCU57_04715	COG1393	Belongs to the ArsC family
KCU57_04745	COG0175	sulfate reduction
KCU57_04750	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KCU57_04755	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KCU57_04765	COG2895	sulfate adenylyltransferase (ATP) activity
KCU57_04765	COG0529	Catalyzes the synthesis of activated sulfate
KCU57_04770	COG0840	transmembrane signaling receptor activity
KCU57_04790	COG1115	amino acid carrier protein
KCU57_04800	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KCU57_04820	COG1609	Transcriptional regulator
KCU57_04835	COG0179	Fumarylacetoacetate (FAA) hydrolase
KCU57_04850	COG3273	potassium ion transport
KCU57_04850	COG0471	metal ion transport
KCU57_04860	COG2022	thiamine diphosphate biosynthetic process
KCU57_04885	COG4974	Belongs to the 'phage' integrase family
KCU57_04925	COG3511	phospholipase C
KCU57_04935	COG0189	ligase activity
KCU57_04945	COG0745	RESPONSE REGULATOR receiver
KCU57_04960	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
KCU57_04985	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KCU57_04990	COG3657	addiction module killer protein
KCU57_05025	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KCU57_05025	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
KCU57_05035	COG1262	PFAM Formylglycine-generating sulfatase enzyme
KCU57_05050	COG1174	glycine betaine transport
KCU57_05055	COG1125	glycine betaine transport
KCU57_05065	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KCU57_05070	COG0564	pseudouridine synthase activity
KCU57_05085	COG4993	Dehydrogenase
KCU57_05095	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
KCU57_05100	COG3387	PFAM Glycoside hydrolase 15-related
KCU57_05150	COG0542	response to heat
KCU57_05175	COG0019	diaminopimelate decarboxylase activity
KCU57_05180	COG4264	IucA IucC family
KCU57_05185	COG2814	Major facilitator Superfamily
KCU57_05190	COG4264	IucA IucC family
KCU57_05200	COG4772	TonB-dependent receptor
KCU57_05210	COG4651	solute:proton antiporter activity
KCU57_05210	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KCU57_05325	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KCU57_05325	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KCU57_05395	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KCU57_05410	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KCU57_05430	COG1295	ribonuclease BN
KCU57_05435	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KCU57_05455	COG0521	Mo-molybdopterin cofactor biosynthetic process
KCU57_05460	COG5297	Belongs to the glycosyl hydrolase family 6
KCU57_05560	COG3537	Alpha-1,2-mannosidase
KCU57_05580	COG1472	Belongs to the glycosyl hydrolase 3 family
KCU57_05590	COG3525	Glycosyl hydrolase, family 20, catalytic domain
KCU57_05595	COG3858	chitin binding
KCU57_05595	COG1388	LysM domain
KCU57_05615	COG0837	glucose binding
KCU57_05625	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KCU57_05635	COG0494	nUDIX hydrolase
KCU57_05640	COG1218	3'(2'),5'-bisphosphate nucleotidase
KCU57_05645	COG3956	TIGRFAM MazG family protein
KCU57_05650	COG1742	UPF0060 membrane protein
KCU57_05655	COG0330	HflC and HflK could
KCU57_05700	COG0697	spore germination
KCU57_05725	COG2124	cytochrome p450
KCU57_05730	COG2124	cytochrome p450
KCU57_05735	COG1141	Ferredoxin
KCU57_05740	COG1028	Short-chain dehydrogenase reductase Sdr
KCU57_05745	COG2124	cytochrome p450
KCU57_05750	COG0142	geranyltranstransferase activity
KCU57_05755	COG1657	PFAM Prenyltransferase squalene oxidase
KCU57_05765	COG1304	FMN binding
KCU57_05810	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KCU57_05815	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KCU57_05820	COG0463	Glycosyl transferase, family 2
KCU57_05825	COG0517	IMP dehydrogenase activity
KCU57_05835	COG2982	Protein involved in outer membrane biogenesis
KCU57_05840	COG1272	protein, Hemolysin III
KCU57_05845	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KCU57_05855	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KCU57_05860	COG0626	cystathionine gamma-synthase activity
KCU57_05865	COG0527	aspartate kinase activity
KCU57_05865	COG0460	homoserine dehydrogenase
KCU57_05870	COG2267	carboxylic ester hydrolase activity
KCU57_05880	COG1760	l-serine dehydratase
KCU57_05895	COG3038	cytochrome b561
KCU57_05915	COG2814	Major facilitator Superfamily
KCU57_05920	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KCU57_05930	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KCU57_05935	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KCU57_05995	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KCU57_06025	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KCU57_06045	COG0840	transmembrane signaling receptor activity
KCU57_06055	COG1113	amino acid transport
KCU57_06075	COG2239	Acts as a magnesium transporter
KCU57_06080	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KCU57_06085	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KCU57_06095	COG1660	Displays ATPase and GTPase activities
KCU57_06105	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KCU57_06120	COG1137	ATPase activity
KCU57_06135	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
KCU57_06180	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KCU57_06205	COG0628	permease
KCU57_06215	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KCU57_06220	COG3178	'Phosphotransferase
KCU57_06235	COG1555	photosystem II stabilization
KCU57_06255	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KCU57_06260	COG1477	protein flavinylation
KCU57_06285	COG4774	siderophore transport
KCU57_06290	COG2146	nitrite reductase [NAD(P)H] activity
KCU57_06300	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KCU57_06305	COG0719	Fe-S assembly protein
KCU57_06310	COG0396	ATPase activity
KCU57_06315	COG0719	Fe-S assembly protein
KCU57_06330	COG0693	protein deglycase activity
KCU57_06345	COG0739	heme binding
KCU57_06360	COG1764	response to oxidative stress
KCU57_06370	COG0384	phenazine biosynthesis protein PhzF
KCU57_06375	COG0527	aspartate kinase activity
KCU57_06400	COG0142	geranyltranstransferase activity
KCU57_06405	COG0629	single-stranded DNA binding
KCU57_06410	COG3550	peptidyl-serine autophosphorylation
KCU57_06425	COG3104	oligopeptide transport
KCU57_06430	COG1297	OPT oligopeptide transporter protein
KCU57_06435	COG0823	Involved in the tonB-independent uptake of proteins
KCU57_06435	COG1506	peptidase
KCU57_06460	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KCU57_06465	COG2879	small protein
KCU57_06470	COG1966	Carbon starvation protein
KCU57_06495	COG0588	phosphoglycerate mutase activity
KCU57_06510	COG2211	Major facilitator Superfamily
KCU57_06520	COG2801	Transposase and inactivated derivatives
KCU57_06540	COG2203	Gaf domain
KCU57_06540	COG3706	GGDEF domain
KCU57_06540	COG4251	negative regulation of phosphorylation
KCU57_06540	COG5001	Diguanylate cyclase
KCU57_06545	COG0835	chemotaxis
KCU57_06550	COG0840	transmembrane signaling receptor activity
KCU57_06555	COG0840	transmembrane signaling receptor activity
KCU57_06560	COG0840	transmembrane signaling receptor activity
KCU57_06565	COG2198	Histidine kinase
KCU57_06565	COG0643	Histidine kinase
KCU57_06575	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KCU57_06595	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
KCU57_06605	COG2205	protein histidine kinase activity
KCU57_06635	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KCU57_06640	COG0735	belongs to the Fur family
KCU57_06675	COG1529	Aldehyde oxidase and xanthine dehydrogenase
KCU57_06680	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
KCU57_06685	COG2080	2 iron, 2 sulfur cluster binding
KCU57_06795	COG1187	pseudouridine synthase activity
KCU57_06820	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KCU57_06840	COG1132	(ABC) transporter
KCU57_06860	COG0583	DNA-binding transcription factor activity
KCU57_06895	COG1981	membrane
KCU57_06920	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KCU57_06925	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KCU57_06935	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KCU57_06940	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KCU57_06945	COG0750	zinc metalloprotease
KCU57_06950	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
KCU57_06955	COG0575	Belongs to the CDS family
KCU57_06960	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KCU57_06970	COG0528	UMP kinase activity
KCU57_06980	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KCU57_07020	COG0024	Methionine aminopeptidase
KCU57_07035	COG1393	Belongs to the ArsC family
KCU57_07040	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KCU57_07050	COG0367	asparagine synthase
KCU57_07090	COG1566	PFAM secretion protein HlyD family protein
KCU57_07095	COG2814	Major facilitator Superfamily
KCU57_07130	COG0557	exoribonuclease II activity
KCU57_07140	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KCU57_07150	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KCU57_07170	COG0704	Plays a role in the regulation of phosphate uptake
KCU57_07180	COG0581	inorganic phosphate transmembrane transporter activity
KCU57_07190	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KCU57_07195	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KCU57_07215	COG0659	secondary active sulfate transmembrane transporter activity
KCU57_07220	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KCU57_07230	COG1024	Enoyl-CoA hydratase
KCU57_07285	COG5002	protein histidine kinase activity
KCU57_07285	COG0784	Response regulator, receiver
KCU57_07285	COG2205	protein histidine kinase activity
KCU57_07290	COG2733	membrane
KCU57_07310	COG0686	Belongs to the AlaDH PNT family
KCU57_07315	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KCU57_07320	COG1396	sequence-specific DNA binding
KCU57_07320	COG1917	Cupin 2, conserved barrel domain protein
KCU57_07325	COG1012	belongs to the aldehyde dehydrogenase family
KCU57_07350	COG2223	nitrite transmembrane transporter activity
KCU57_07360	COG0243	molybdopterin cofactor binding
KCU57_07380	COG0477	Major facilitator Superfamily
KCU57_07390	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KCU57_07395	COG0174	glutamine synthetase
KCU57_07400	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
KCU57_07405	COG0174	glutamine synthetase
KCU57_07415	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
KCU57_07420	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
KCU57_07440	COG3842	ATPase activity
KCU57_07445	COG1176	ABC-type spermidine putrescine transport system, permease component I
KCU57_07450	COG1177	transmembrane transport
KCU57_07455	COG1012	belongs to the aldehyde dehydrogenase family
KCU57_07470	COG4535	Mg2 and Co2 transporter CorC
KCU57_07485	COG1702	phosphate starvation-inducible protein PhoH
KCU57_07500	COG0741	lytic transglycosylase activity
KCU57_07505	COG0723	plastoquinol--plastocyanin reductase activity
KCU57_07510	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KCU57_07520	COG2857	Cytochrome c1
KCU57_07525	COG0625	glutathione transferase activity
KCU57_07530	COG2969	positive regulation of protein catabolic process
KCU57_07570	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
KCU57_07575	COG1028	Short-chain dehydrogenase reductase Sdr
KCU57_07580	COG2095	MarC family integral membrane protein
KCU57_07590	COG1611	Belongs to the LOG family
KCU57_07595	COG3275	phosphorelay sensor kinase activity
KCU57_07640	COG0556	nucleotide-excision repair
KCU57_07675	COG2948	multi-organism process
KCU57_07765	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KCU57_07775	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KCU57_07780	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KCU57_07830	COG0438	transferase activity, transferring glycosyl groups
KCU57_07835	COG0438	transferase activity, transferring glycosyl groups
KCU57_07845	COG0438	transferase activity, transferring glycosyl groups
KCU57_07865	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KCU57_07875	COG1960	acyl-CoA dehydrogenase activity
KCU57_07920	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KCU57_07925	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KCU57_07925	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
KCU57_07930	COG0802	atpase or kinase
KCU57_07935	COG0860	N-Acetylmuramoyl-L-alanine amidase
KCU57_07940	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KCU57_07960	COG1028	Short-chain dehydrogenase reductase Sdr
KCU57_07980	COG2081	HI0933 family
KCU57_07985	COG4681	YaeQ
KCU57_07990	COG0564	pseudouridine synthase activity
KCU57_08000	COG0625	glutathione transferase activity
KCU57_08005	COG0657	acetylesterase activity
KCU57_08010	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
KCU57_08035	COG0513	Belongs to the DEAD box helicase family
KCU57_08040	COG0488	(ABC) transporter
KCU57_08050	COG4290	ribonuclease
KCU57_08055	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KCU57_08065	COG1472	Belongs to the glycosyl hydrolase 3 family
KCU57_08105	COG1846	Transcriptional regulator
KCU57_08120	COG0386	Belongs to the glutathione peroxidase family
KCU57_08190	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KCU57_08195	COG0084	hydrolase, TatD family'
KCU57_08210	COG1960	acyl-CoA dehydrogenase activity
KCU57_08220	COG0305	Participates in initiation and elongation during chromosome replication
KCU57_08225	COG0415	Belongs to the DNA photolyase family
KCU57_08240	COG0583	DNA-binding transcription factor activity
KCU57_08255	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KCU57_08300	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
KCU57_08305	COG2867	negative regulation of translational initiation
KCU57_08315	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KCU57_08320	COG0735	belongs to the Fur family
KCU57_08325	COG0497	DNA recombination
KCU57_08330	COG1420	regulation of RNA biosynthetic process
KCU57_08335	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KCU57_08340	COG0443	Heat shock 70 kDa protein
KCU57_08345	COG0484	heat shock protein binding
KCU57_08350	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
KCU57_08355	COG0287	Prephenate dehydrogenase
KCU57_08355	COG1605	Chorismate mutase
KCU57_08365	COG1132	(ABC) transporter
KCU57_08415	COG2850	peptidyl-arginine hydroxylation
KCU57_08420	COG2885	chlorophyll binding
KCU57_08465	COG1131	(ABC) transporter
KCU57_08470	COG1725	Transcriptional regulator
KCU57_08480	COG0386	Belongs to the glutathione peroxidase family
KCU57_08495	COG2900	Belongs to the SlyX family
KCU57_08515	COG0646	methionine synthase
KCU57_08515	COG1410	methionine synthase
KCU57_08520	COG1410	methionine synthase
KCU57_08520	COG0646	methionine synthase
KCU57_08525	COG2226	methyltransferase
KCU57_08530	COG1960	acyl-CoA dehydrogenase activity
KCU57_08540	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KCU57_08545	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KCU57_08555	COG2902	Dehydrogenase
KCU57_08610	COG2925	Exonuclease
KCU57_08620	COG3844	kynureninase activity
KCU57_08635	COG0288	reversible hydration of carbon dioxide
KCU57_08705	COG0316	Belongs to the HesB IscA family
KCU57_08740	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KCU57_08745	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KCU57_08750	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
KCU57_08760	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
KCU57_08795	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
KCU57_08810	COG1228	amidohydrolase
KCU57_08825	COG4221	oxidoreductase activity
KCU57_08865	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KCU57_08870	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KCU57_08875	COG0077	Prephenate dehydratase
KCU57_08875	COG1605	Chorismate mutase
KCU57_08900	COG0583	DNA-binding transcription factor activity
KCU57_08975	COG0577	efflux transmembrane transporter activity
KCU57_08975	COG1136	(ABC) transporter
KCU57_09005	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KCU57_09005	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KCU57_09010	COG1105	Belongs to the carbohydrate kinase PfkB family
KCU57_09015	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KCU57_09015	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
KCU57_09020	COG1609	Transcriptional regulator
KCU57_09030	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
KCU57_09070	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KCU57_09085	COG1253	flavin adenine dinucleotide binding
KCU57_09095	COG0306	phosphate transporter
KCU57_09115	COG0504	CTP synthase activity
KCU57_09130	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
KCU57_09135	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
KCU57_09140	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
KCU57_09150	COG2840	Smr protein MutS2
KCU57_09155	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
KCU57_09165	COG1238	metal cluster binding
KCU57_09180	COG1534	Rna-binding protein
KCU57_09185	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
KCU57_09190	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KCU57_09195	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KCU57_09200	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KCU57_09210	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KCU57_09215	COG1546	Belongs to the CinA family
KCU57_09220	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
KCU57_09225	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KCU57_09230	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KCU57_09235	COG2137	regulation of response to DNA damage stimulus
KCU57_09240	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KCU57_09290	COG1294	oxidase, subunit
KCU57_09300	COG4988	ABC transporter
KCU57_09305	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KCU57_09310	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KCU57_09355	COG4133	protoheme IX ABC transporter activity
KCU57_09360	COG0436	Aminotransferase
KCU57_09390	COG1187	pseudouridine synthase activity
KCU57_09395	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KCU57_09400	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KCU57_09405	COG2350	Protein conserved in bacteria
KCU57_09440	COG0395	ABC-type sugar transport system, permease component
KCU57_09455	COG0129	dihydroxy-acid dehydratase activity
KCU57_09470	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KCU57_09475	COG3842	ATPase activity
KCU57_09480	COG0354	folic acid binding
KCU57_09490	COG2009	succinate dehydrogenase
KCU57_09495	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
KCU57_09510	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
KCU57_09520	COG4591	ABC-type transport system involved in lipoprotein release permease component
KCU57_09540	COG0811	peptide transport
KCU57_09550	COG1132	(ABC) transporter
KCU57_09555	COG1663	tetraacyldisaccharide 4'-kinase activity
KCU57_09565	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KCU57_09580	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KCU57_09590	COG0582	viral genome integration into host DNA
KCU57_09710	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
KCU57_09715	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KCU57_09725	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KCU57_09750	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KCU57_09755	COG2258	MOSC domain
KCU57_09765	COG0505	Belongs to the CarA family
KCU57_09775	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
KCU57_09780	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KCU57_09790	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KCU57_09845	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
KCU57_09850	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
KCU57_09865	COG1024	Enoyl-CoA hydratase
KCU57_09875	COG1024	Enoyl-CoA hydratase
KCU57_09880	COG1024	Enoyl-CoA hydratase
KCU57_09905	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KCU57_09920	COG0346	lactoylglutathione lyase activity
KCU57_09930	COG1304	FMN binding
KCU57_09935	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KCU57_09940	COG1649	PFAM Uncharacterised BCR, COG1649
KCU57_10010	COG0784	Response regulator, receiver
KCU57_10010	COG2205	protein histidine kinase activity
KCU57_10015	COG2183	response to ionizing radiation
KCU57_10020	COG0784	Response regulator, receiver
KCU57_10020	COG4191	Histidine kinase
KCU57_10030	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KCU57_10030	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
KCU57_10050	COG3243	poly(R)-hydroxyalkanoic acid synthase
KCU57_10060	COG1183	phosphatidylcholine synthase activity
KCU57_10065	COG1028	Short-chain dehydrogenase reductase Sdr
KCU57_10080	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
KCU57_10090	COG0668	transmembrane transport
KCU57_10095	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
KCU57_10110	COG1914	H( )-stimulated, divalent metal cation uptake system
KCU57_10120	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
KCU57_10125	COG1501	Belongs to the glycosyl hydrolase 31 family
KCU57_10175	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KCU57_10175	COG0519	Catalyzes the synthesis of GMP from XMP
KCU57_10175	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KCU57_10175	COG0519	Catalyzes the synthesis of GMP from XMP
KCU57_10210	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KCU57_10210	COG0519	Catalyzes the synthesis of GMP from XMP
KCU57_10220	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KCU57_10235	COG0475	glutathione-regulated potassium exporter activity
KCU57_10235	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KCU57_10240	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KCU57_10250	COG0746	molybdenum cofactor guanylyltransferase activity
KCU57_10260	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KCU57_10270	COG1426	Protein conserved in bacteria
KCU57_10280	COG0820	rRNA (adenine-C2-)-methyltransferase activity
KCU57_10295	COG1250	3-hydroxyacyl-CoA dehydrogenase
KCU57_10295	COG1024	Enoyl-CoA hydratase
KCU57_10300	COG0183	Belongs to the thiolase family
KCU57_10305	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KCU57_10315	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KCU57_10320	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
KCU57_10330	COG0776	regulation of translation
KCU57_10335	COG0539	negative regulation of cytoplasmic translation
KCU57_10340	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
KCU57_10345	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KCU57_10355	COG2957	Belongs to the agmatine deiminase family
KCU57_10360	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KCU57_10380	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KCU57_10400	COG0316	Belongs to the HesB IscA family
KCU57_10400	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
KCU57_10415	COG0428	transporter
KCU57_10430	COG1530	ribonuclease E activity
KCU57_10450	COG2801	Transposase and inactivated derivatives
KCU57_10485	COG1132	(ABC) transporter
KCU57_10510	COG0438	transferase activity, transferring glycosyl groups
KCU57_10530	COG4106	trans-aconitate 2-methyltransferase activity
KCU57_10550	COG2244	polysaccharide biosynthetic process
KCU57_10580	COG3038	cytochrome b561
KCU57_10600	COG1595	DNA-templated transcription, initiation
KCU57_10655	COG0038	chloride channel
KCU57_10660	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KCU57_10680	COG1674	ftsk spoiiie
KCU57_10685	COG0492	ferredoxin-NADP+ reductase activity
KCU57_10695	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
KCU57_10705	COG0542	response to heat
KCU57_10725	COG0482	sulfurtransferase activity
KCU57_10730	COG2915	High frequency lysogenization protein hflD homolog
KCU57_10790	COG0784	Response regulator, receiver
KCU57_10790	COG0835	chemotaxis
KCU57_10800	COG1558	bacterial-type flagellum-dependent cell motility
KCU57_10810	COG1749	Flagellar hook protein flgE
KCU57_10825	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
KCU57_10840	COG4786	Flagellar basal body rod
KCU57_10840	COG4786	Flagellar basal body rod
KCU57_10840	COG1256	bacterial-type flagellum assembly
KCU57_10840	COG1256	bacterial-type flagellum assembly
KCU57_10845	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KCU57_10850	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KCU57_10855	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
KCU57_10875	COG2197	response regulator
KCU57_10885	COG2201	protein-glutamate methylesterase activity
KCU57_10905	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KCU57_10915	COG1028	Short-chain dehydrogenase reductase Sdr
KCU57_10950	COG1677	Flagellar hook-basal body complex protein FliE
KCU57_11000	COG3190	flagellar
KCU57_11010	COG1987	bacterial-type flagellum assembly
KCU57_11015	COG1684	flagellar biosynthetic protein fliR
KCU57_11060	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
KCU57_11065	COG0643	Histidine kinase
KCU57_11065	COG0784	Response regulator, receiver
KCU57_11065	COG2198	Histidine kinase
KCU57_11070	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KCU57_11080	COG1192	Involved in chromosome partitioning
KCU57_11095	COG0745	RESPONSE REGULATOR receiver
KCU57_11115	COG0840	transmembrane signaling receptor activity
KCU57_11120	COG0840	transmembrane signaling receptor activity
KCU57_11125	COG0840	transmembrane signaling receptor activity
KCU57_11125	COG0840	transmembrane signaling receptor activity
KCU57_11135	COG0840	transmembrane signaling receptor activity
KCU57_11145	COG0840	transmembrane signaling receptor activity
KCU57_11150	COG0840	transmembrane signaling receptor activity
KCU57_11155	COG0840	transmembrane signaling receptor activity
KCU57_11165	COG0840	transmembrane signaling receptor activity
KCU57_11175	COG0835	chemotaxis
KCU57_11185	COG0840	transmembrane signaling receptor activity
KCU57_11195	COG0840	transmembrane signaling receptor activity
KCU57_11220	COG3706	GGDEF domain
KCU57_11250	COG0318	PFAM AMP-dependent synthetase and ligase
KCU57_11255	COG1024	Enoyl-CoA hydratase
KCU57_11260	COG2198	Histidine kinase
KCU57_11260	COG2205	protein histidine kinase activity
KCU57_11260	COG0784	Response regulator, receiver
KCU57_11300	COG0800	Aldolase
KCU57_11315	COG3734	2-keto-3-deoxy-galactonokinase
KCU57_11320	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
KCU57_11330	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KCU57_11340	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KCU57_11345	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
KCU57_11360	COG0351	phosphomethylpyrimidine kinase
KCU57_11380	COG0583	DNA-binding transcription factor activity
KCU57_11385	COG1741	Belongs to the pirin family
KCU57_11430	COG1024	Enoyl-CoA hydratase
KCU57_11445	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KCU57_11465	COG0277	FAD linked oxidase domain protein
KCU57_11470	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KCU57_11485	COG0531	amino acid
KCU57_11490	COG0531	amino acid
KCU57_11495	COG0235	Class ii aldolase
KCU57_11500	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
KCU57_11505	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
KCU57_11520	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KCU57_11520	COG0140	phosphoribosyl-ATP diphosphatase activity
KCU57_11535	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KCU57_11545	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KCU57_11550	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KCU57_11555	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
KCU57_11565	COG0124	histidyl-tRNA synthetase
KCU57_11570	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KCU57_11580	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KCU57_11590	COG2951	lytic endotransglycosylase activity
KCU57_11595	COG0083	homoserine kinase activity
KCU57_11600	COG0460	homoserine dehydrogenase
KCU57_11600	COG0527	aspartate kinase activity
KCU57_11615	COG1012	belongs to the aldehyde dehydrogenase family
KCU57_11630	COG0167	dihydroorotate dehydrogenase activity
KCU57_11635	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KCU57_11660	COG0671	phosphoesterase, PA-phosphatase related
KCU57_11675	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
KCU57_11695	COG0166	Belongs to the GPI family
KCU57_11710	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
KCU57_11720	COG0617	tRNA 3'-terminal CCA addition
KCU57_11740	COG0860	N-Acetylmuramoyl-L-alanine amidase
KCU57_11745	COG0477	Major facilitator Superfamily
KCU57_11750	COG2115	Belongs to the xylose isomerase family
KCU57_11755	COG1070	Carbohydrate kinase
KCU57_11765	COG1501	Belongs to the glycosyl hydrolase 31 family
KCU57_11785	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KCU57_11805	COG0165	Argininosuccinate lyase
KCU57_11810	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KCU57_11820	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
KCU57_11825	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KCU57_11830	COG0137	argininosuccinate synthase activity
KCU57_11835	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KCU57_11850	COG2166	iron-sulfur cluster assembly
KCU57_11880	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
KCU57_11895	COG4677	pectinesterase activity
KCU57_11925	COG0402	S-adenosylhomocysteine deaminase activity
KCU57_11930	COG3548	integral membrane protein
KCU57_11940	COG1509	lysine 2,3-aminomutase activity
KCU57_11945	COG2203	Gaf domain
KCU57_11945	COG5001	Diguanylate cyclase
KCU57_11945	COG4251	negative regulation of phosphorylation
KCU57_11945	COG3706	GGDEF domain
KCU57_11970	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KCU57_11975	COG1862	Preprotein translocase
KCU57_11985	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KCU57_11995	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KCU57_12005	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KCU57_12010	COG3291	Pkd domain containing protein
KCU57_12015	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KCU57_12020	COG0405	Gamma-glutamyltransferase
KCU57_12025	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
KCU57_12040	COG0742	ribosomal rna small subunit methyltransferase
KCU57_12075	COG3507	Belongs to the glycosyl hydrolase 43 family
KCU57_12110	COG0531	amino acid
KCU57_12125	COG0006	proline dipeptidase activity
KCU57_12135	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KCU57_12150	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KCU57_12155	COG3938	Belongs to the proline racemase family
KCU57_12165	COG0552	protein localization to endoplasmic reticulum
KCU57_12170	COG1194	a g-specific adenine glycosylase
KCU57_12210	COG0582	viral genome integration into host DNA
KCU57_12255	COG0835	chemotaxis
KCU57_12260	COG0840	transmembrane signaling receptor activity
KCU57_12265	COG0840	transmembrane signaling receptor activity
KCU57_12290	COG3300	MHYT domain
KCU57_12290	COG5001	Diguanylate cyclase
KCU57_12295	COG1185	polyribonucleotide nucleotidyltransferase activity
KCU57_12305	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KCU57_12320	COG0195	Participates in both transcription termination and antitermination
KCU57_12335	COG1007	ATP synthesis coupled electron transport
KCU57_12370	COG1034	ATP synthesis coupled electron transport
KCU57_12375	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
KCU57_12380	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
KCU57_12385	COG0649	NAD binding
KCU57_12390	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KCU57_12400	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KCU57_12420	COG1028	Short-chain dehydrogenase reductase Sdr
KCU57_12440	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KCU57_12505	COG2890	protein-(glutamine-N5) methyltransferase activity
KCU57_12515	COG0688	phosphatidylethanolamine metabolic process
KCU57_12520	COG0741	lytic transglycosylase activity
KCU57_12525	COG0433	COG0433 Predicted ATPase
KCU57_12530	COG0494	nUDIX hydrolase
KCU57_12545	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KCU57_12565	COG1714	RDD family
KCU57_12570	COG0717	Belongs to the dCTP deaminase family
KCU57_12575	COG0489	protein tyrosine kinase activity
KCU57_12585	COG4771	TonB-dependent receptor
KCU57_12590	COG4771	TonB-dependent receptor
KCU57_12595	COG0457	Tetratricopeptide repeat
KCU57_12610	COG3590	peptidase
KCU57_12680	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KCU57_12685	COG2311	Membrane
KCU57_12690	COG1047	Peptidyl-prolyl cis-trans
KCU57_12695	COG0791	NLP P60 protein
KCU57_12700	COG0791	NLP P60 protein
KCU57_12715	COG1607	acyl-coa hydrolase
KCU57_12725	COG1301	dicarboxylic acid transport
KCU57_12730	COG1785	Belongs to the alkaline phosphatase family
KCU57_12740	COG0037	tRNA processing
KCU57_12745	COG1722	exodeoxyribonuclease VII activity
KCU57_12750	COG0142	geranyltranstransferase activity
KCU57_12760	COG1858	cytochrome C peroxidase
KCU57_12785	COG0515	serine threonine protein kinase
KCU57_12785	COG2815	serine threonine protein kinase
KCU57_12790	COG0631	protein serine/threonine phosphatase activity
KCU57_12890	COG0312	modulator of DNA gyrase
KCU57_12900	COG0312	modulator of DNA gyrase
KCU57_12920	COG2968	Membrane
KCU57_12935	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KCU57_12950	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KCU57_12965	COG0495	leucyl-tRNA aminoacylation
KCU57_12975	COG3118	belongs to the thioredoxin family
KCU57_12990	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
KCU57_13000	COG2040	homocysteine
KCU57_13005	COG0833	amino acid
KCU57_13015	COG0346	lactoylglutathione lyase activity
KCU57_13035	COG2878	Part of a membrane complex involved in electron transport
KCU57_13050	COG1595	DNA-templated transcription, initiation
KCU57_13075	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KCU57_13095	COG0251	oxidation-reduction process
KCU57_13105	COG0392	lysyltransferase activity
KCU57_13105	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KCU57_13135	COG2814	Major facilitator Superfamily
KCU57_13140	COG1902	pentaerythritol trinitrate reductase activity
KCU57_13145	COG2824	Alkylphosphonate utilization operon protein PhnA
KCU57_13150	COG1047	Peptidyl-prolyl cis-trans
KCU57_13155	COG1077	Cell shape determining protein MreB Mrl
KCU57_13190	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KCU57_13200	COG1451	nucleotide metabolic process
KCU57_13220	COG2205	protein histidine kinase activity
KCU57_13220	COG2198	Histidine kinase
KCU57_13220	COG0784	Response regulator, receiver
KCU57_13230	COG2186	Transcriptional regulator
KCU57_13235	COG3250	beta-galactosidase activity
KCU57_13330	COG0183	Belongs to the thiolase family
KCU57_13340	COG0443	Heat shock 70 kDa protein
KCU57_13370	COG1793	dna ligase
KCU57_13370	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
KCU57_13375	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
KCU57_13375	COG1793	dna ligase
KCU57_13380	COG1201	RNA secondary structure unwinding
KCU57_13395	COG1278	Cold shock
KCU57_13400	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
KCU57_13405	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
KCU57_13410	COG1472	Belongs to the glycosyl hydrolase 3 family
KCU57_13420	COG2954	triphosphatase activity
KCU57_13430	COG0745	RESPONSE REGULATOR receiver
KCU57_13435	COG1381	Involved in DNA repair and RecF pathway recombination
KCU57_13440	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KCU57_13455	COG0681	Belongs to the peptidase S26 family
KCU57_13460	COG0481	GTPase activity
KCU57_13465	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KCU57_13500	COG2855	membrane
KCU57_13515	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KCU57_13535	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
KCU57_13545	COG0534	Mate efflux family protein
KCU57_13550	COG0335	large ribosomal subunit rRNA binding
KCU57_13555	COG0336	Belongs to the RNA methyltransferase TrmD family
KCU57_13560	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KCU57_13565	COG0228	four-way junction DNA binding
KCU57_13580	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KCU57_13605	COG0475	glutathione-regulated potassium exporter activity
KCU57_13615	COG0625	glutathione transferase activity
KCU57_13620	COG1082	Xylose isomerase domain protein TIM barrel
KCU57_13640	COG1172	Belongs to the binding-protein-dependent transport system permease family
KCU57_13645	COG1172	Belongs to the binding-protein-dependent transport system permease family
KCU57_13650	COG1129	ABC transporter
KCU57_13655	COG1879	ABC-type sugar transport system periplasmic component
KCU57_13660	COG1012	belongs to the aldehyde dehydrogenase family
KCU57_13680	COG0129	dihydroxy-acid dehydratase activity
KCU57_13705	COG2207	Transcriptional regulator
KCU57_13750	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KCU57_13775	COG4794	Type iii secretion
KCU57_13805	COG0745	RESPONSE REGULATOR receiver
KCU57_13830	COG1595	DNA-templated transcription, initiation
KCU57_13850	COG3152	Membrane
KCU57_13860	COG0156	8-amino-7-oxononanoate synthase activity
KCU57_13870	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
KCU57_13875	COG1845	cytochrome c oxidase, subunit III
KCU57_13880	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KCU57_13920	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
KCU57_13935	COG0196	riboflavin kinase activity
KCU57_13955	COG0728	peptidoglycan biosynthetic process
KCU57_13965	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KCU57_13975	COG0211	Belongs to the bacterial ribosomal protein bL27 family
KCU57_13980	COG0261	This protein binds to 23S rRNA in the presence of protein L20
KCU57_13985	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KCU57_13990	COG0824	Thioesterase
KCU57_14000	COG1024	Enoyl-CoA hydratase
KCU57_14000	COG1250	3-hydroxyacyl-CoA dehydrogenase
KCU57_14005	COG1946	Acyl-CoA thioesterase
KCU57_14020	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
KCU57_14055	COG1073	alpha beta
KCU57_14080	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KCU57_14125	COG1643	Atp-dependent helicase
KCU57_14130	COG0783	Belongs to the Dps family
KCU57_14135	COG0514	ATP-dependent DNA helicase (RecQ)
KCU57_14155	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KCU57_14160	COG0602	queuosine metabolic process
KCU57_14170	COG2885	chlorophyll binding
KCU57_14185	COG0848	biopolymer transport protein
KCU57_14195	COG0824	Thioesterase
KCU57_14200	COG2255	four-way junction helicase activity
KCU57_14205	COG3158	transport of potassium into the cell
KCU57_14210	COG0632	four-way junction helicase activity
KCU57_14220	COG0217	transcriptional regulatory protein
KCU57_14260	COG3142	Participates in the control of copper homeostasis
KCU57_14265	COG1446	asparaginase
KCU57_14295	COG2201	protein-glutamate methylesterase activity
KCU57_14300	COG0643	Histidine kinase
KCU57_14300	COG2198	Histidine kinase
KCU57_14300	COG0784	Response regulator, receiver
KCU57_14305	COG0840	transmembrane signaling receptor activity
KCU57_14310	COG0835	chemotaxis
KCU57_14325	COG0189	ligase activity
KCU57_14350	COG1199	ATP-dependent helicase activity
KCU57_14360	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KCU57_14365	COG1216	Glycosyl transferase, family 2
KCU57_14370	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KCU57_14390	COG4585	Histidine kinase
KCU57_14400	COG0850	regulation of cytokinetic process
KCU57_14405	COG2894	cell division
KCU57_14410	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
KCU57_14420	COG2205	protein histidine kinase activity
KCU57_14425	COG0745	RESPONSE REGULATOR receiver
KCU57_14435	COG2194	sulfuric ester hydrolase activity
KCU57_14520	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KCU57_14520	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KCU57_14530	COG0753	catalase activity
KCU57_14590	COG1063	alcohol dehydrogenase
KCU57_14600	COG3459	Glycosyltransferase 36 associated
KCU57_14695	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
KCU57_14725	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KCU57_14735	COG0330	HflC and HflK could
KCU57_14740	COG0330	HflC and HflK could
KCU57_14745	COG0604	alcohol dehydrogenase
KCU57_14765	COG0678	peroxiredoxin activity
KCU57_14775	COG4953	penicillin-binding protein 1C
KCU57_14795	COG2373	Large extracellular alpha-helical protein
KCU57_14840	COG0372	Belongs to the citrate synthase family
KCU57_14895	COG2161	toxin-antitoxin pair type II binding
KCU57_14900	COG4115	mRNA cleavage
KCU57_14955	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KCU57_14960	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KCU57_14965	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KCU57_14975	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KCU57_14980	COG1028	Short-chain dehydrogenase reductase Sdr
KCU57_14985	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KCU57_14990	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KCU57_15000	COG1399	metal-binding, possibly nucleic acid-binding protein
KCU57_15025	COG0714	Associated with various cellular activities
KCU57_15045	COG0537	adenosine 5'-monophosphoramidase activity
KCU57_15085	COG1002	Type II restriction enzyme, methylase subunits
KCU57_15190	COG0314	molybdopterin synthase activity
KCU57_15195	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
KCU57_15200	COG0315	cyclic pyranopterin monophosphate synthase activity
KCU57_15210	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KCU57_15215	COG1234	tRNA 3'-trailer cleavage
KCU57_15225	COG0859	PFAM glycosyl transferase family 9
KCU57_15305	COG0631	protein serine/threonine phosphatase activity
KCU57_15310	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KCU57_15315	COG0328	RNA-DNA hybrid ribonuclease activity
KCU57_15325	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KCU57_15330	COG3942	CHAP domain
KCU57_15330	COG1388	LysM domain
KCU57_15365	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KCU57_15375	COG0544	peptidyl-prolyl cis-trans isomerase activity
KCU57_15420	COG0473	3-isopropylmalate dehydrogenase activity
KCU57_15435	COG4783	chaperone-mediated protein folding
KCU57_15450	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KCU57_15455	COG0248	Ppx GppA phosphatase
KCU57_15460	COG0438	transferase activity, transferring glycosyl groups
KCU57_15470	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KCU57_15480	COG3291	Pkd domain containing protein
KCU57_15485	COG2833	Protein of unknown function (DUF455)
KCU57_15505	COG0285	dihydrofolate synthase activity
KCU57_15510	COG0588	phosphoglycerate mutase activity
KCU57_15530	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
KCU57_15535	COG4208	sulfate ABC transporter
KCU57_15540	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
KCU57_15545	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
KCU57_15550	COG0156	8-amino-7-oxononanoate synthase activity
KCU57_15565	COG2885	chlorophyll binding
KCU57_15585	COG0667	Aldo Keto reductase
KCU57_15600	COG0446	pyridine nucleotide-disulphide oxidoreductase
KCU57_15600	COG1902	pentaerythritol trinitrate reductase activity
KCU57_15645	COG0625	glutathione transferase activity
KCU57_15650	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KCU57_15660	COG0039	L-malate dehydrogenase activity
KCU57_15670	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KCU57_15675	COG1217	gtp-binding protein TYPA
KCU57_15690	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
KCU57_15700	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
KCU57_15705	COG0203	ribosomal protein L17
KCU57_15730	COG0201	protein transport
KCU57_15740	COG1841	ribosomal large subunit assembly
KCU57_15765	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KCU57_15770	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KCU57_15775	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KCU57_15780	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KCU57_15785	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KCU57_15790	COG0255	Belongs to the universal ribosomal protein uL29 family
KCU57_15815	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KCU57_15820	COG0089	rRNA binding
KCU57_15825	COG0088	Forms part of the polypeptide exit tunnel
KCU57_15835	COG0051	transcription antitermination factor activity, RNA binding
KCU57_15840	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KCU57_15845	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KCU57_15860	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KCU57_15870	COG0222	ribosome binding
KCU57_15885	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KCU57_15890	COG0250	Participates in transcription elongation, termination and antitermination
KCU57_15895	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KCU57_15905	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KCU57_15925	COG0012	GTP binding
KCU57_15930	COG0193	aminoacyl-tRNA hydrolase activity
KCU57_15940	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KCU57_15965	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
KCU57_15970	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KCU57_16015	COG0488	(ABC) transporter
KCU57_16085	COG3634	alkyl hydroperoxide reductase activity
KCU57_16090	COG0583	DNA-binding transcription factor activity
KCU57_16105	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KCU57_16130	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KCU57_16135	COG0697	spore germination
KCU57_16175	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KCU57_16180	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KCU57_16190	COG2096	Adenosyltransferase
KCU57_16200	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
KCU57_16205	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KCU57_16210	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
KCU57_16215	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KCU57_16220	COG2967	ApaG domain
KCU57_16225	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KCU57_16255	COG1704	LemA family
KCU57_16260	COG0861	Integral membrane protein TerC family
KCU57_16265	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KCU57_16275	COG0642	Histidine kinase
KCU57_16290	COG4181	ATPase activity
KCU57_16295	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
KCU57_16315	COG4771	TonB-dependent receptor
KCU57_16325	COG0667	Aldo Keto reductase
KCU57_16330	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KCU57_16350	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KCU57_16370	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KCU57_16435	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KCU57_16445	COG0494	nUDIX hydrolase
KCU57_16460	COG0739	heme binding
KCU57_16470	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
KCU57_16475	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KCU57_16485	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KCU57_16490	COG1181	Belongs to the D-alanine--D-alanine ligase family
KCU57_16500	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KCU57_16515	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KCU57_16530	COG3116	cell division
KCU57_16535	COG0275	rRNA processing
KCU57_16540	COG2001	Belongs to the MraZ family
KCU57_16570	COG0792	nuclease activity
KCU57_16575	COG0277	FAD linked oxidase domain protein
KCU57_16580	COG0745	RESPONSE REGULATOR receiver
KCU57_16585	COG2205	protein histidine kinase activity
KCU57_16595	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
KCU57_16600	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
KCU57_16620	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
KCU57_16625	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KCU57_16630	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
KCU57_16645	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KCU57_16645	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KCU57_16655	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KCU57_16685	COG0477	Major facilitator Superfamily
KCU57_16690	COG0488	(ABC) transporter
KCU57_16695	COG0242	peptide deformylase activity
KCU57_16705	COG1960	acyl-CoA dehydrogenase activity
KCU57_16715	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KCU57_16725	COG1696	Membrane protein involved in D-alanine export
KCU57_16745	COG1215	transferase activity, transferring glycosyl groups
KCU57_16755	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KCU57_16760	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KCU57_16805	COG2188	Transcriptional regulator
KCU57_16815	COG1450	Type ii and iii secretion system protein
KCU57_16830	COG3166	PFAM Fimbrial assembly family protein
KCU57_16835	COG3156	type II secretion system protein K
KCU57_16840	COG4795	General secretion pathway protein
KCU57_16845	COG2165	general secretion pathway protein
KCU57_16850	COG4970	Tfp pilus assembly protein FimT
KCU57_16855	COG2165	general secretion pathway protein
KCU57_16860	COG1459	type II secretion system
KCU57_16865	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KCU57_16870	COG1404	Belongs to the peptidase S8 family
KCU57_16875	COG5295	Hep Hag repeat protein
KCU57_16885	COG0840	transmembrane signaling receptor activity
KCU57_16890	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KCU57_16890	COG0047	phosphoribosylformylglycinamidine synthase activity
KCU57_16895	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KCU57_16900	COG4974	Belongs to the 'phage' integrase family
KCU57_16925	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KCU57_16960	COG1183	phosphatidylcholine synthase activity
KCU57_16970	COG0442	prolyl-tRNA aminoacylation
KCU57_16985	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
KCU57_16990	COG1127	ABC transporter
KCU57_16995	COG3218	ABC-type transport auxiliary lipoprotein component
KCU57_16995	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
KCU57_17025	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KCU57_17030	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KCU57_17035	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
KCU57_17035	COG0662	Cupin 2, conserved barrel domain protein
KCU57_17060	COG2086	electron transfer activity
KCU57_17075	COG0546	phosphoglycolate phosphatase activity
KCU57_17075	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
KCU57_17080	COG0277	FAD linked oxidase domain protein
KCU57_17085	COG0300	oxidoreductase activity
KCU57_17090	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KCU57_17110	COG0493	'glutamate synthase
KCU57_17130	COG0438	transferase activity, transferring glycosyl groups
KCU57_17130	COG1216	Glycosyl transferase, family 2
KCU57_17135	COG1216	Glycosyl transferase, family 2
KCU57_17135	COG0438	transferase activity, transferring glycosyl groups
KCU57_17140	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KCU57_17155	COG0626	cystathionine gamma-synthase activity
KCU57_17185	COG0625	glutathione transferase activity
KCU57_17195	COG0513	Belongs to the DEAD box helicase family
KCU57_17200	COG0720	synthase
KCU57_17210	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
KCU57_17215	COG1956	GAF domain-containing protein
KCU57_17225	COG4206	TonB-dependent receptor
KCU57_17230	COG0546	phosphoglycolate phosphatase activity
KCU57_17255	COG0339	signal peptide processing
KCU57_17260	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KCU57_17270	COG2217	Heavy metal translocating P-type atpase
KCU57_17285	COG2132	Multicopper oxidase
KCU57_17300	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KCU57_17320	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KCU57_17335	COG0355	proton-transporting ATP synthase activity, rotational mechanism
KCU57_17350	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KCU57_17360	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KCU57_17370	COG0356	it plays a direct role in the translocation of protons across the membrane
KCU57_17385	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KCU57_17390	COG0508	dehydrogenase complex catalyzes the overall conversion of
KCU57_17425	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KCU57_17430	COG0697	spore germination
KCU57_17435	COG1666	GTP binding
KCU57_17445	COG1187	pseudouridine synthase activity
KCU57_17470	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KCU57_17470	COG2205	protein histidine kinase activity
KCU57_17495	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KCU57_17555	COG0842	Transport permease protein
KCU57_17560	COG1131	(ABC) transporter
KCU57_17565	COG0025	NhaP-type Na H and K H
KCU57_17575	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
KCU57_17580	COG1573	uracil-dna glycosylase
KCU57_17590	COG3384	dioxygenase
KCU57_17615	COG0667	Aldo Keto reductase
KCU57_17625	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KCU57_17630	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KCU57_17650	COG3706	GGDEF domain
KCU57_17660	COG5001	Diguanylate cyclase
KCU57_17695	COG4106	trans-aconitate 2-methyltransferase activity
KCU57_17705	COG2076	Multidrug Resistance protein
KCU57_17715	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KCU57_17740	COG3275	phosphorelay sensor kinase activity
KCU57_17745	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
KCU57_17765	COG0531	amino acid
KCU57_17780	COG5297	Belongs to the glycosyl hydrolase family 6
KCU57_17780	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
KCU57_17795	COG0741	lytic transglycosylase activity
KCU57_17820	COG0598	Magnesium transport protein CorA
KCU57_17825	COG1113	amino acid transport
KCU57_17830	COG0697	spore germination
KCU57_17855	COG2267	carboxylic ester hydrolase activity
KCU57_17960	COG1192	Involved in chromosome partitioning
KCU57_17970	COG0840	transmembrane signaling receptor activity
KCU57_17985	COG2353	YceI-like domain
KCU57_18015	COG0584	glycerophosphoryl diester phosphodiesterase
KCU57_18030	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
KCU57_18050	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KCU57_18055	COG0459	protein refolding
KCU57_18070	COG1324	tolerance protein
KCU57_18080	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KCU57_18090	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
KCU57_18095	COG0511	ligase activity, forming carbon-carbon bonds
KCU57_18100	COG0439	Biotin carboxylase
KCU57_18115	COG2264	protein methyltransferase activity
KCU57_18135	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
KCU57_18160	COG2267	carboxylic ester hydrolase activity
KCU57_18170	COG0138	bifunctional purine biosynthesis protein purh
KCU57_18175	COG0151	Belongs to the GarS family
KCU57_18185	COG1289	transmembrane transporter activity
KCU57_18190	COG2814	Major facilitator Superfamily
KCU57_18230	COG2816	NAD+ diphosphatase activity
KCU57_18270	COG2906	2 iron, 2 sulfur cluster binding
KCU57_18275	COG1051	belongs to the nudix hydrolase family
KCU57_18300	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
KCU57_18315	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KCU57_18320	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KCU57_18325	COG0730	response to heat
KCU57_18340	COG0134	indole-3-glycerol-phosphate synthase activity
KCU57_18345	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KCU57_18365	COG1597	lipid kinase activity
KCU57_18380	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
KCU57_18395	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KCU57_18400	COG2111	Na H antiporter
KCU57_18400	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KCU57_18405	COG1006	Multisubunit Na H antiporter MnhC subunit
KCU57_18410	COG0651	ATP synthesis coupled electron transport
KCU57_18420	COG2212	antiporter activity
KCU57_18425	COG1320	monovalent cation:proton antiporter activity
KCU57_18430	COG0530	calcium, potassium:sodium antiporter activity
KCU57_18445	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
KCU57_18465	COG3104	oligopeptide transport
KCU57_18515	COG3227	Zinc metalloprotease (Elastase)
KCU57_18520	COG0513	Belongs to the DEAD box helicase family
KCU57_18545	COG2354	Protein conserved in bacteria
KCU57_18570	COG3264	Mechanosensitive ion channel
KCU57_18570	COG1196	nuclear chromosome segregation
KCU57_18575	COG1028	Short-chain dehydrogenase reductase Sdr
KCU57_18575	COG0604	alcohol dehydrogenase
KCU57_18575	COG3321	synthase
KCU57_18595	COG1595	DNA-templated transcription, initiation
KCU57_18615	COG1802	Transcriptional regulator
KCU57_18630	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
KCU57_18660	COG1414	Transcriptional regulator
KCU57_18665	COG0738	Major facilitator superfamily
KCU57_18670	COG3254	rhamnose metabolic process
KCU57_18675	COG4948	Mandelate Racemase Muconate Lactonizing
KCU57_18680	COG0179	Fumarylacetoacetate (FAA) hydrolase
KCU57_18685	COG1028	Short-chain dehydrogenase reductase Sdr
KCU57_18715	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KCU57_18730	COG4807	Protein conserved in bacteria
KCU57_18750	COG4773	Receptor
KCU57_18765	COG0823	Involved in the tonB-independent uptake of proteins
KCU57_18765	COG1506	peptidase
KCU57_18825	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KCU57_18845	COG0628	permease
KCU57_18850	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KCU57_18855	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KCU57_18860	COG0753	catalase activity
KCU57_18885	COG1136	(ABC) transporter
KCU57_18890	COG0577	efflux transmembrane transporter activity
KCU57_18910	COG0697	spore germination
KCU57_18925	COG0180	Tryptophanyl-tRNA synthetase
KCU57_18960	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
KCU57_18965	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
KCU57_18965	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
KCU57_18975	COG3228	Belongs to the MtfA family
KCU57_19005	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KCU57_19030	COG2084	Dehydrogenase
KCU57_19035	COG1902	pentaerythritol trinitrate reductase activity
KCU57_19045	COG2814	Major facilitator Superfamily
KCU57_19050	COG0583	DNA-binding transcription factor activity
KCU57_19065	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KCU57_19070	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KCU57_19080	COG1764	response to oxidative stress
KCU57_19085	COG1846	Transcriptional regulator
KCU57_19090	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
KCU57_19105	COG0523	cobalamin synthesis protein
KCU57_19115	COG1742	UPF0060 membrane protein
KCU57_19125	COG3245	cytochrome
KCU57_19135	COG1960	acyl-CoA dehydrogenase activity
KCU57_19140	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KCU57_19155	COG1278	Cold shock
KCU57_19175	COG1271	oxidase subunit
KCU57_19180	COG1294	oxidase, subunit
KCU57_19205	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KCU57_19220	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KCU57_19255	COG0463	Glycosyl transferase, family 2
KCU57_19265	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KCU57_19270	COG3100	YcgL domain-containing protein
KCU57_19290	COG0745	RESPONSE REGULATOR receiver
KCU57_19295	COG3387	PFAM Glycoside hydrolase 15-related
KCU57_19300	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KCU57_19315	COG0408	coproporphyrinogen oxidase activity
KCU57_19325	COG2323	membrane
KCU57_19330	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KCU57_19330	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KCU57_19345	COG0589	response to stress
KCU57_19375	COG0210	DNA helicase
KCU57_19430	COG0463	Glycosyl transferase, family 2
KCU57_19440	COG1475	DNA binding
KCU57_19445	COG1192	Involved in chromosome partitioning
KCU57_19450	COG0357	Ribosomal RNA small subunit methyltransferase G
KCU57_19455	COG2091	lysine biosynthetic process via aminoadipic acid
KCU57_19480	COG0477	Major facilitator Superfamily
KCU57_19500	COG1971	Probably functions as a manganese efflux pump
KCU57_19505	COG2205	protein histidine kinase activity
KCU57_19515	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KCU57_19520	COG3459	Glycosyltransferase 36 associated
KCU57_19525	COG2211	Major facilitator Superfamily
KCU57_19530	COG3265	gluconokinase activity
KCU57_19535	COG2911	Protein conserved in bacteria
KCU57_19540	COG0729	surface antigen
KCU57_19565	COG3132	Protein of unknown function, DUF480
KCU57_19585	COG0284	orotidine-5'-phosphate decarboxylase activity
KCU57_19600	COG1609	Transcriptional regulator
KCU57_19610	COG2937	Belongs to the GPAT DAPAT family
KCU57_19635	COG2211	Major facilitator Superfamily
KCU57_19650	COG3693	PFAM glycoside hydrolase, family 10
KCU57_19670	COG3386	PFAM SMP-30 Gluconolaconase
KCU57_19690	COG0246	Mannitol dehydrogenase
KCU57_19695	COG1472	Belongs to the glycosyl hydrolase 3 family
KCU57_19705	COG4948	Mandelate Racemase Muconate Lactonizing
KCU57_19715	COG3661	Belongs to the glycosyl hydrolase 67 family
KCU57_19725	COG2115	Belongs to the xylose isomerase family
KCU57_19730	COG0037	tRNA processing
KCU57_19750	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KCU57_19760	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KCU57_19770	COG0805	protein transport
KCU57_19780	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KCU57_19780	COG0519	Catalyzes the synthesis of GMP from XMP
KCU57_19785	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KCU57_19805	COG0210	DNA helicase
KCU57_19810	COG1435	thymidine kinase activity
KCU57_19820	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
KCU57_19835	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
KCU57_19850	COG1119	ATPase activity
KCU57_19865	COG0706	membrane insertase activity
KCU57_19870	COG0594	ribonuclease P activity