locus-tag	class	description
KHA79_00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KHA79_00020	COG0187	DNA topoisomerase II activity
KHA79_00025	COG1266	CAAX protease self-immunity
KHA79_00030	COG0501	Belongs to the peptidase M48B family
KHA79_00065	COG0583	DNA-binding transcription factor activity
KHA79_00085	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KHA79_00125	COG4772	TonB-dependent receptor
KHA79_00135	COG3284	Transcriptional regulator
KHA79_00145	COG1012	belongs to the aldehyde dehydrogenase family
KHA79_00180	COG1304	FMN binding
KHA79_00185	COG2186	Transcriptional regulator
KHA79_00245	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KHA79_00265	COG4771	TonB-dependent receptor
KHA79_00290	COG3507	Belongs to the glycosyl hydrolase 43 family
KHA79_00320	COG3186	Phenylalanine-4-hydroxylase
KHA79_00325	COG1522	sequence-specific DNA binding
KHA79_00330	COG1752	Esterase of the alpha-beta hydrolase superfamily
KHA79_00345	COG0671	phosphoesterase, PA-phosphatase related
KHA79_00355	COG0861	Integral membrane protein TerC family
KHA79_00360	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KHA79_00395	COG1929	Belongs to the glycerate kinase type-1 family
KHA79_00405	COG0531	amino acid
KHA79_00410	COG4566	intracellular signal transduction
KHA79_00415	COG4191	Histidine kinase
KHA79_00420	COG1285	pathogenesis
KHA79_00435	COG1322	Protein conserved in bacteria
KHA79_00440	COG0386	Belongs to the glutathione peroxidase family
KHA79_00445	COG2853	Lipoprotein
KHA79_00460	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
KHA79_00465	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
KHA79_00470	COG1127	ABC transporter
KHA79_00475	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
KHA79_00480	COG1074	ATP-dependent DNA helicase activity
KHA79_00485	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KHA79_00575	COG0840	transmembrane signaling receptor activity
KHA79_00580	COG0477	Major facilitator Superfamily
KHA79_00585	COG0302	gtp cyclohydrolase
KHA79_00590	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KHA79_00620	COG0730	response to heat
KHA79_00635	COG2951	lytic endotransglycosylase activity
KHA79_00640	COG0676	glucose-6-phosphate 1-epimerase activity
KHA79_00660	COG3135	benzoate transporter
KHA79_00695	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KHA79_00705	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
KHA79_00710	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
KHA79_00715	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
KHA79_00720	COG0493	'glutamate synthase
KHA79_00725	COG0069	glutamate synthase activity
KHA79_00725	COG0070	glutamate synthase
KHA79_00725	COG0067	glutamate synthase
KHA79_00770	COG1111	helicase
KHA79_00770	COG1205	dead DEAH box helicase
KHA79_00810	COG2271	Major facilitator Superfamily
KHA79_00860	COG1192	Involved in chromosome partitioning
KHA79_00865	COG2062	phosphohistidine phosphatase, SixA
KHA79_00875	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KHA79_00880	COG2050	protein possibly involved in aromatic compounds catabolism
KHA79_00890	COG2267	carboxylic ester hydrolase activity
KHA79_00905	COG1881	PFAM PEBP family protein
KHA79_00910	COG1968	undecaprenyl-diphosphatase activity
KHA79_00915	COG0174	glutamine synthetase
KHA79_00920	COG0347	Belongs to the P(II) protein family
KHA79_00925	COG0004	ammonium transporteR
KHA79_00930	COG3852	Histidine kinase
KHA79_00935	COG2204	response regulator
KHA79_00940	COG2032	superoxide dismutase activity
KHA79_00945	COG2032	superoxide dismutase activity
KHA79_00975	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KHA79_00980	COG1960	acyl-CoA dehydrogenase activity
KHA79_00990	COG3245	cytochrome
KHA79_01015	COG0523	cobalamin synthesis protein
KHA79_01020	COG0697	spore germination
KHA79_01030	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
KHA79_01035	COG1846	Transcriptional regulator
KHA79_01040	COG1764	response to oxidative stress
KHA79_01050	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KHA79_01055	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KHA79_01075	COG2814	Major facilitator Superfamily
KHA79_01080	COG1404	Belongs to the peptidase S8 family
KHA79_01105	COG1902	pentaerythritol trinitrate reductase activity
KHA79_01110	COG2084	Dehydrogenase
KHA79_01135	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KHA79_01165	COG3228	Belongs to the MtfA family
KHA79_01175	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
KHA79_01175	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
KHA79_01180	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
KHA79_01210	COG3237	CsbD-like
KHA79_01220	COG0180	Tryptophanyl-tRNA synthetase
KHA79_01250	COG0339	signal peptide processing
KHA79_01260	COG0583	DNA-binding transcription factor activity
KHA79_01265	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
KHA79_01270	COG2224	Isocitrate lyase
KHA79_01305	COG0659	secondary active sulfate transmembrane transporter activity
KHA79_01340	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KHA79_01345	COG2130	NADP-dependent
KHA79_01360	COG1187	pseudouridine synthase activity
KHA79_01380	COG0084	hydrolase, TatD family'
KHA79_01395	COG0842	Transport permease protein
KHA79_01400	COG1131	(ABC) transporter
KHA79_01405	COG0633	Ferredoxin
KHA79_01405	COG0543	2 iron, 2 sulfur cluster binding
KHA79_01415	COG1476	TRANSCRIPTIONal
KHA79_01425	COG4555	ABC transporter
KHA79_01445	COG0625	glutathione transferase activity
KHA79_01515	COG1199	ATP-dependent helicase activity
KHA79_01555	COG0628	permease
KHA79_01565	COG0129	dihydroxy-acid dehydratase activity
KHA79_01570	COG2133	pyrroloquinoline quinone binding
KHA79_01635	COG5463	Belongs to the UPF0441 family
KHA79_01640	COG0754	glutathionylspermidine amidase activity
KHA79_01650	COG0714	Associated with various cellular activities
KHA79_01695	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KHA79_01710	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KHA79_01715	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KHA79_01775	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
KHA79_01780	COG1040	competence protein
KHA79_01785	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KHA79_01815	COG0606	chelatase, subunit chli
KHA79_01820	COG2960	long-chain fatty acid transporting porin activity
KHA79_01845	COG1166	arginine decarboxylase activity
KHA79_01850	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KHA79_01855	COG1819	glycosyl
KHA79_01860	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
KHA79_01860	COG2755	lipolytic protein G-D-S-L family
KHA79_01875	COG4221	oxidoreductase activity
KHA79_01895	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KHA79_01915	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KHA79_01925	COG2814	Major facilitator Superfamily
KHA79_01940	COG0739	heme binding
KHA79_01945	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KHA79_01975	COG1064	alcohol dehydrogenase
KHA79_01980	COG2234	aminopeptidase activity
KHA79_01990	COG4942	peptidase
KHA79_01995	COG0793	Belongs to the peptidase S41A family
KHA79_02035	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KHA79_02040	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KHA79_02045	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
KHA79_02075	COG0109	protoheme IX farnesyltransferase activity
KHA79_02090	COG0358	DNA primase activity
KHA79_02095	COG1295	ribonuclease BN
KHA79_02110	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KHA79_02115	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KHA79_02120	COG2308	Evidence 4 Homologs of previously reported genes of
KHA79_02135	COG2133	pyrroloquinoline quinone binding
KHA79_02160	COG0531	amino acid
KHA79_02180	COG4771	TonB-dependent receptor
KHA79_02225	COG5383	Protein conserved in bacteria
KHA79_02240	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KHA79_02245	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KHA79_02260	COG1652	LysM domain
KHA79_02270	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KHA79_02275	COG1518	maintenance of DNA repeat elements
KHA79_02330	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KHA79_02335	COG3118	belongs to the thioredoxin family
KHA79_02345	COG2884	Cell division ATP-binding protein ftsE
KHA79_02350	COG2177	Part of the ABC transporter FtsEX involved in
KHA79_02355	COG2201	protein-glutamate methylesterase activity
KHA79_02360	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KHA79_02365	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KHA79_02370	COG2860	membrane
KHA79_02375	COG1252	NADH dehydrogenase
KHA79_02385	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KHA79_02400	COG0534	Mate efflux family protein
KHA79_02405	COG0616	signal peptide processing
KHA79_02415	COG1028	Short-chain dehydrogenase reductase Sdr
KHA79_02430	COG0009	L-threonylcarbamoyladenylate synthase
KHA79_02435	COG1754	DNA topoisomerase type I activity
KHA79_02435	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KHA79_02440	COG1714	RDD family
KHA79_02455	COG0758	DNA mediated transformation
KHA79_02460	COG1652	LysM domain
KHA79_02465	COG0242	peptide deformylase activity
KHA79_02470	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KHA79_02475	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KHA79_02475	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KHA79_02480	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KHA79_02530	COG1490	D-aminoacyl-tRNA deacylase activity
KHA79_02535	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KHA79_02560	COG1609	Transcriptional regulator
KHA79_02570	COG0366	Alpha amylase catalytic
KHA79_02575	COG0366	Alpha amylase catalytic
KHA79_02595	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KHA79_02650	COG1309	transcriptional regulator
KHA79_02700	COG3546	catalase activity
KHA79_02705	COG3685	Protein conserved in bacteria
KHA79_02710	COG3685	Protein conserved in bacteria
KHA79_02715	COG1028	Short-chain dehydrogenase reductase Sdr
KHA79_02725	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
KHA79_02740	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KHA79_02755	COG0028	Belongs to the TPP enzyme family
KHA79_02760	COG4191	Histidine kinase
KHA79_02790	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
KHA79_02805	COG3645	SOS response
KHA79_02825	COG1648	precorrin-2 dehydrogenase activity
KHA79_02825	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KHA79_02835	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KHA79_02835	COG1116	anion transmembrane transporter activity
KHA79_02840	COG2223	nitrite transmembrane transporter activity
KHA79_02845	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KHA79_02850	COG2146	nitrite reductase [NAD(P)H] activity
KHA79_02855	COG0243	molybdopterin cofactor binding
KHA79_02880	COG1640	4-alpha-glucanotransferase
KHA79_02885	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KHA79_02895	COG0297	glycogen (starch) synthase activity
KHA79_02905	COG2204	response regulator
KHA79_02930	COG0181	hydroxymethylbilane synthase activity
KHA79_02945	COG1733	regulation of RNA biosynthetic process
KHA79_02960	COG1505	serine-type exopeptidase activity
KHA79_02965	COG0436	Aminotransferase
KHA79_02975	COG2832	Protein of unknown function (DUF454)
KHA79_03030	COG2226	methyltransferase
KHA79_03040	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KHA79_03045	COG0308	aminopeptidase N
KHA79_03050	COG0596	Alpha beta hydrolase
KHA79_03050	COG0508	dehydrogenase complex catalyzes the overall conversion of
KHA79_03070	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KHA79_03075	COG1077	Cell shape determining protein MreB Mrl
KHA79_03080	COG1792	Involved in formation and maintenance of cell shape
KHA79_03090	COG0768	penicillin binding
KHA79_03095	COG0772	Belongs to the SEDS family
KHA79_03105	COG5434	Belongs to the glycosyl hydrolase 28 family
KHA79_03110	COG2951	lytic endotransglycosylase activity
KHA79_03120	COG1686	Belongs to the peptidase S11 family
KHA79_03135	COG0321	lipoyl(octanoyl) transferase activity
KHA79_03140	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KHA79_03165	COG1051	belongs to the nudix hydrolase family
KHA79_03165	COG1056	cytidyltransferase-related domain
KHA79_03185	COG1090	epimerase
KHA79_03195	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
KHA79_03200	COG0673	inositol 2-dehydrogenase activity
KHA79_03205	COG2823	Periplasmic or secreted lipoprotein
KHA79_03215	COG2205	protein histidine kinase activity
KHA79_03215	COG2202	Pas domain
KHA79_03220	COG0784	Response regulator, receiver
KHA79_03225	COG4191	Histidine kinase
KHA79_03235	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KHA79_03260	COG3250	beta-galactosidase activity
KHA79_03275	COG2188	Transcriptional regulator
KHA79_03285	COG1609	Transcriptional regulator
KHA79_03290	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KHA79_03295	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KHA79_03305	COG0617	tRNA 3'-terminal CCA addition
KHA79_03350	COG2207	Transcriptional regulator
KHA79_03375	COG2205	protein histidine kinase activity
KHA79_03390	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
KHA79_03395	COG3791	Glutathione-dependent formaldehyde-activating
KHA79_03405	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KHA79_03415	COG0697	spore germination
KHA79_03460	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
KHA79_03485	COG0436	Aminotransferase
KHA79_03490	COG1162	GTPase activity
KHA79_03515	COG2211	Major facilitator Superfamily
KHA79_03525	COG1028	Short-chain dehydrogenase reductase Sdr
KHA79_03530	COG2851	Citrate transporter
KHA79_03545	COG0642	Histidine kinase
KHA79_03575	COG1301	dicarboxylic acid transport
KHA79_03580	COG0280	phosphate acetyltransferase
KHA79_03580	COG0281	malic enzyme
KHA79_03645	COG1560	Kdo2-lipid A biosynthetic process
KHA79_03650	COG1519	Transferase
KHA79_03655	COG1538	Outer membrane efflux protein
KHA79_03660	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
KHA79_03670	COG3706	GGDEF domain
KHA79_03675	COG0473	3-isopropylmalate dehydrogenase activity
KHA79_03680	COG0066	3-isopropylmalate dehydratase activity
KHA79_03700	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KHA79_03725	COG0840	transmembrane signaling receptor activity
KHA79_03755	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
KHA79_03765	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
KHA79_03785	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KHA79_03795	COG0671	phosphoesterase, PA-phosphatase related
KHA79_03810	COG1940	carbohydrate kinase activity
KHA79_03820	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KHA79_03835	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
KHA79_03845	COG1773	rubredoxin
KHA79_03860	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KHA79_03870	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KHA79_03895	COG3079	Belongs to the UPF0149 family
KHA79_03900	COG0006	proline dipeptidase activity
KHA79_03910	COG3038	cytochrome b561
KHA79_03915	COG1309	transcriptional regulator
KHA79_03920	COG0006	proline dipeptidase activity
KHA79_03935	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KHA79_03940	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KHA79_03945	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
KHA79_03950	COG1561	YicC-like family, N-terminal region
KHA79_03955	COG0194	GDP metabolic process
KHA79_03960	COG1758	RNA polymerase activity
KHA79_03965	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KHA79_03985	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KHA79_03995	COG0254	rRNA binding
KHA79_04000	COG0372	Belongs to the citrate synthase family
KHA79_04010	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
KHA79_04040	COG0714	Associated with various cellular activities
KHA79_04070	COG1301	dicarboxylic acid transport
KHA79_04075	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KHA79_04100	COG0739	heme binding
KHA79_04105	COG1376	ErfK ybiS ycfS ynhG family protein
KHA79_04145	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
KHA79_04150	COG4149	molybdate abc transporter
KHA79_04155	COG0725	ABC transporter, periplasmic molybdate-binding protein
KHA79_04165	COG0640	Transcriptional regulator
KHA79_04180	COG3047	cAMP biosynthetic process
KHA79_04185	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KHA79_04230	COG0469	pyruvate kinase activity
KHA79_04235	COG3588	fructose-bisphosphate aldolase
KHA79_04240	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
KHA79_04275	COG1648	precorrin-2 dehydrogenase activity
KHA79_04275	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KHA79_04290	COG2198	Histidine kinase
KHA79_04290	COG2205	protein histidine kinase activity
KHA79_04290	COG0784	Response regulator, receiver
KHA79_04295	COG1393	Belongs to the ArsC family
KHA79_04325	COG0175	sulfate reduction
KHA79_04330	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KHA79_04335	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KHA79_04345	COG2895	sulfate adenylyltransferase (ATP) activity
KHA79_04345	COG0529	Catalyzes the synthesis of activated sulfate
KHA79_04360	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KHA79_04370	COG1609	Transcriptional regulator
KHA79_04385	COG0179	Fumarylacetoacetate (FAA) hydrolase
KHA79_04400	COG3273	potassium ion transport
KHA79_04400	COG0471	metal ion transport
KHA79_04410	COG2022	thiamine diphosphate biosynthetic process
KHA79_04430	COG0174	glutamine synthetase
KHA79_04435	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
KHA79_04445	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
KHA79_04460	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KHA79_04485	COG3511	phospholipase C
KHA79_04495	COG0189	ligase activity
KHA79_04505	COG0745	RESPONSE REGULATOR receiver
KHA79_04520	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
KHA79_04585	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
KHA79_04585	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KHA79_04595	COG1262	PFAM Formylglycine-generating sulfatase enzyme
KHA79_04610	COG1174	glycine betaine transport
KHA79_04615	COG1125	glycine betaine transport
KHA79_04625	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KHA79_04630	COG0564	pseudouridine synthase activity
KHA79_04655	COG4993	Dehydrogenase
KHA79_04665	COG3387	PFAM Glycoside hydrolase 15-related
KHA79_04670	COG1877	trehalose-phosphatase activity
KHA79_04690	COG0454	-acetyltransferase
KHA79_04710	COG0542	response to heat
KHA79_04735	COG0019	diaminopimelate decarboxylase activity
KHA79_04740	COG4264	IucA IucC family
KHA79_04745	COG2814	Major facilitator Superfamily
KHA79_04750	COG4264	IucA IucC family
KHA79_04760	COG4772	TonB-dependent receptor
KHA79_04770	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KHA79_04770	COG4651	solute:proton antiporter activity
KHA79_04800	COG0488	(ABC) transporter
KHA79_04820	COG2755	lipolytic protein G-D-S-L family
KHA79_04820	COG0657	acetylesterase activity
KHA79_04870	COG0217	transcriptional regulatory protein
KHA79_04880	COG0632	four-way junction helicase activity
KHA79_04885	COG3158	transport of potassium into the cell
KHA79_04890	COG2255	four-way junction helicase activity
KHA79_04895	COG0824	Thioesterase
KHA79_04905	COG0848	biopolymer transport protein
KHA79_04920	COG2885	chlorophyll binding
KHA79_04930	COG0602	queuosine metabolic process
KHA79_04935	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KHA79_04955	COG0514	ATP-dependent DNA helicase (RecQ)
KHA79_04960	COG0783	Belongs to the Dps family
KHA79_04965	COG1643	Atp-dependent helicase
KHA79_05010	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KHA79_05035	COG1073	alpha beta
KHA79_05065	COG4638	Rieske (2fe-2S)
KHA79_05080	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
KHA79_05095	COG1946	Acyl-CoA thioesterase
KHA79_05100	COG1024	Enoyl-CoA hydratase
KHA79_05110	COG0824	Thioesterase
KHA79_05115	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KHA79_05120	COG0261	This protein binds to 23S rRNA in the presence of protein L20
KHA79_05125	COG0211	Belongs to the bacterial ribosomal protein bL27 family
KHA79_05140	COG0728	peptidoglycan biosynthetic process
KHA79_05160	COG0196	riboflavin kinase activity
KHA79_05175	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
KHA79_05195	COG0750	zinc metalloprotease
KHA79_05210	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KHA79_05215	COG1845	cytochrome c oxidase, subunit III
KHA79_05220	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
KHA79_05240	COG3152	Membrane
KHA79_05295	COG4794	Type iii secretion
KHA79_05320	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KHA79_05345	COG1317	bacterial-type flagellum organization
KHA79_05365	COG2207	Transcriptional regulator
KHA79_05390	COG0129	dihydroxy-acid dehydratase activity
KHA79_05395	COG1028	Short-chain dehydrogenase reductase Sdr
KHA79_05410	COG1012	belongs to the aldehyde dehydrogenase family
KHA79_05415	COG1879	ABC-type sugar transport system periplasmic component
KHA79_05420	COG1129	ABC transporter
KHA79_05425	COG1172	Belongs to the binding-protein-dependent transport system permease family
KHA79_05430	COG1172	Belongs to the binding-protein-dependent transport system permease family
KHA79_05440	COG1082	Xylose isomerase domain protein TIM barrel
KHA79_05445	COG0625	glutathione transferase activity
KHA79_05465	COG0475	glutathione-regulated potassium exporter activity
KHA79_05490	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KHA79_05510	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KHA79_05520	COG0335	large ribosomal subunit rRNA binding
KHA79_05525	COG0534	Mate efflux family protein
KHA79_05550	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
KHA79_05555	COG2894	cell division
KHA79_05560	COG0850	regulation of cytokinetic process
KHA79_05570	COG4585	Histidine kinase
KHA79_05595	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KHA79_05600	COG1216	Glycosyl transferase, family 2
KHA79_05605	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KHA79_05615	COG1199	ATP-dependent helicase activity
KHA79_05635	COG0189	ligase activity
KHA79_05650	COG0835	chemotaxis
KHA79_05655	COG0840	transmembrane signaling receptor activity
KHA79_05660	COG0643	Histidine kinase
KHA79_05660	COG0784	Response regulator, receiver
KHA79_05660	COG2198	Histidine kinase
KHA79_05665	COG2201	protein-glutamate methylesterase activity
KHA79_05685	COG1446	asparaginase
KHA79_05690	COG3142	Participates in the control of copper homeostasis
KHA79_05790	COG3537	Alpha-1,2-mannosidase
KHA79_05810	COG1472	Belongs to the glycosyl hydrolase 3 family
KHA79_05820	COG3525	Glycosyl hydrolase, family 20, catalytic domain
KHA79_05825	COG1388	LysM domain
KHA79_05825	COG3858	chitin binding
KHA79_05845	COG0837	glucose binding
KHA79_05855	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KHA79_05865	COG0494	nUDIX hydrolase
KHA79_05870	COG1218	3'(2'),5'-bisphosphate nucleotidase
KHA79_05875	COG3956	TIGRFAM MazG family protein
KHA79_05880	COG1742	UPF0060 membrane protein
KHA79_05885	COG0330	HflC and HflK could
KHA79_05950	COG2124	cytochrome p450
KHA79_05955	COG2124	cytochrome p450
KHA79_05960	COG1141	Ferredoxin
KHA79_05965	COG1028	Short-chain dehydrogenase reductase Sdr
KHA79_05970	COG2124	cytochrome p450
KHA79_05975	COG0142	geranyltranstransferase activity
KHA79_05980	COG1657	PFAM Prenyltransferase squalene oxidase
KHA79_05990	COG1304	FMN binding
KHA79_05995	COG1960	acyl-CoA dehydrogenase activity
KHA79_06030	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KHA79_06035	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KHA79_06040	COG0463	Glycosyl transferase, family 2
KHA79_06045	COG0517	IMP dehydrogenase activity
KHA79_06050	COG2982	Protein involved in outer membrane biogenesis
KHA79_06055	COG1272	protein, Hemolysin III
KHA79_06060	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KHA79_06070	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KHA79_06075	COG0626	cystathionine gamma-synthase activity
KHA79_06085	COG0596	Alpha beta hydrolase
KHA79_06085	COG0508	dehydrogenase complex catalyzes the overall conversion of
KHA79_06095	COG1760	l-serine dehydratase
KHA79_06110	COG3038	cytochrome b561
KHA79_06125	COG2205	protein histidine kinase activity
KHA79_06125	COG2198	Histidine kinase
KHA79_06125	COG0784	Response regulator, receiver
KHA79_06130	COG2814	Major facilitator Superfamily
KHA79_06135	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KHA79_06145	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KHA79_06150	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KHA79_06190	COG0789	Transcriptional regulator
KHA79_06210	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KHA79_06225	COG0519	Catalyzes the synthesis of GMP from XMP
KHA79_06240	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KHA79_06260	COG0840	transmembrane signaling receptor activity
KHA79_06270	COG1113	amino acid transport
KHA79_06290	COG2239	Acts as a magnesium transporter
KHA79_06295	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KHA79_06300	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KHA79_06310	COG1660	Displays ATPase and GTPase activities
KHA79_06320	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KHA79_06335	COG1137	ATPase activity
KHA79_06350	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
KHA79_06395	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KHA79_06415	COG0628	permease
KHA79_06425	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KHA79_06430	COG3178	'Phosphotransferase
KHA79_06445	COG1555	photosystem II stabilization
KHA79_06470	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KHA79_06475	COG1477	protein flavinylation
KHA79_06500	COG4774	siderophore transport
KHA79_06505	COG2146	nitrite reductase [NAD(P)H] activity
KHA79_06515	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KHA79_06520	COG0719	Fe-S assembly protein
KHA79_06525	COG0396	ATPase activity
KHA79_06530	COG0719	Fe-S assembly protein
KHA79_06545	COG0693	protein deglycase activity
KHA79_06560	COG0739	heme binding
KHA79_06575	COG1764	response to oxidative stress
KHA79_06585	COG0384	phenazine biosynthesis protein PhzF
KHA79_06590	COG0527	aspartate kinase activity
KHA79_06605	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KHA79_06615	COG0142	geranyltranstransferase activity
KHA79_06620	COG0629	single-stranded DNA binding
KHA79_06635	COG1297	OPT oligopeptide transporter protein
KHA79_06640	COG0823	Involved in the tonB-independent uptake of proteins
KHA79_06640	COG1506	peptidase
KHA79_06655	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KHA79_06660	COG2879	small protein
KHA79_06665	COG1966	Carbon starvation protein
KHA79_06670	COG1741	Belongs to the pirin family
KHA79_06700	COG1515	deoxyribonuclease V activity
KHA79_06735	COG2203	Gaf domain
KHA79_06735	COG3706	GGDEF domain
KHA79_06735	COG4251	negative regulation of phosphorylation
KHA79_06735	COG5001	Diguanylate cyclase
KHA79_06740	COG0835	chemotaxis
KHA79_06745	COG0840	transmembrane signaling receptor activity
KHA79_06750	COG0840	transmembrane signaling receptor activity
KHA79_06760	COG0643	Histidine kinase
KHA79_06760	COG2198	Histidine kinase
KHA79_06770	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KHA79_06790	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
KHA79_06835	COG0735	belongs to the Fur family
KHA79_06905	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KHA79_06970	COG1187	pseudouridine synthase activity
KHA79_06995	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KHA79_07015	COG1132	(ABC) transporter
KHA79_07075	COG1981	membrane
KHA79_07085	COG0825	malonyl-CoA metabolic process
KHA79_07105	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KHA79_07125	COG0750	zinc metalloprotease
KHA79_07130	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
KHA79_07135	COG0575	Belongs to the CDS family
KHA79_07140	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KHA79_07150	COG0528	UMP kinase activity
KHA79_07160	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KHA79_07200	COG0024	Methionine aminopeptidase
KHA79_07215	COG1393	Belongs to the ArsC family
KHA79_07220	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KHA79_07230	COG0367	asparagine synthase
KHA79_07265	COG1566	PFAM secretion protein HlyD family protein
KHA79_07270	COG2814	Major facilitator Superfamily
KHA79_07310	COG0557	exoribonuclease II activity
KHA79_07320	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KHA79_07345	COG0704	Plays a role in the regulation of phosphate uptake
KHA79_07355	COG0581	inorganic phosphate transmembrane transporter activity
KHA79_07370	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KHA79_07390	COG0659	secondary active sulfate transmembrane transporter activity
KHA79_07395	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KHA79_07405	COG1024	Enoyl-CoA hydratase
KHA79_07450	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KHA79_07450	COG0116	Belongs to the methyltransferase superfamily
KHA79_07460	COG0784	Response regulator, receiver
KHA79_07460	COG5002	protein histidine kinase activity
KHA79_07460	COG2205	protein histidine kinase activity
KHA79_07465	COG2733	membrane
KHA79_07485	COG0686	Belongs to the AlaDH PNT family
KHA79_07490	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KHA79_07495	COG1917	Cupin 2, conserved barrel domain protein
KHA79_07495	COG1396	sequence-specific DNA binding
KHA79_07500	COG1012	belongs to the aldehyde dehydrogenase family
KHA79_07520	COG2223	nitrite transmembrane transporter activity
KHA79_07530	COG0243	molybdopterin cofactor binding
KHA79_07550	COG0477	Major facilitator Superfamily
KHA79_07560	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KHA79_07565	COG0174	glutamine synthetase
KHA79_07570	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
KHA79_07575	COG0174	glutamine synthetase
KHA79_07585	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
KHA79_07590	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
KHA79_07610	COG3842	ATPase activity
KHA79_07615	COG1176	ABC-type spermidine putrescine transport system, permease component I
KHA79_07620	COG1177	transmembrane transport
KHA79_07625	COG1012	belongs to the aldehyde dehydrogenase family
KHA79_07640	COG4535	Mg2 and Co2 transporter CorC
KHA79_07655	COG1702	phosphate starvation-inducible protein PhoH
KHA79_07670	COG0741	lytic transglycosylase activity
KHA79_07675	COG0723	plastoquinol--plastocyanin reductase activity
KHA79_07680	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KHA79_07690	COG2857	Cytochrome c1
KHA79_07695	COG0625	glutathione transferase activity
KHA79_07700	COG2969	positive regulation of protein catabolic process
KHA79_07720	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KHA79_07770	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
KHA79_07775	COG1028	Short-chain dehydrogenase reductase Sdr
KHA79_07780	COG2095	MarC family integral membrane protein
KHA79_07790	COG1611	Belongs to the LOG family
KHA79_07795	COG3275	phosphorelay sensor kinase activity
KHA79_07845	COG0556	nucleotide-excision repair
KHA79_07960	COG1741	Belongs to the pirin family
KHA79_07965	COG0583	DNA-binding transcription factor activity
KHA79_07985	COG0351	phosphomethylpyrimidine kinase
KHA79_08000	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
KHA79_08005	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KHA79_08015	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KHA79_08025	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
KHA79_08030	COG3734	2-keto-3-deoxy-galactonokinase
KHA79_08045	COG0800	Aldolase
KHA79_08060	COG1070	Carbohydrate kinase
KHA79_08065	COG2115	Belongs to the xylose isomerase family
KHA79_08070	COG0477	Major facilitator Superfamily
KHA79_08080	COG0860	N-Acetylmuramoyl-L-alanine amidase
KHA79_08100	COG0617	tRNA 3'-terminal CCA addition
KHA79_08110	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
KHA79_08125	COG0166	Belongs to the GPI family
KHA79_08220	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
KHA79_08235	COG0671	phosphoesterase, PA-phosphatase related
KHA79_08260	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KHA79_08265	COG0167	dihydroorotate dehydrogenase activity
KHA79_08280	COG1012	belongs to the aldehyde dehydrogenase family
KHA79_08295	COG0460	homoserine dehydrogenase
KHA79_08295	COG0527	aspartate kinase activity
KHA79_08305	COG2951	lytic endotransglycosylase activity
KHA79_08315	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KHA79_08325	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KHA79_08330	COG0124	histidyl-tRNA synthetase
KHA79_08340	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
KHA79_08345	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KHA79_08350	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KHA79_08360	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KHA79_08375	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KHA79_08375	COG0140	phosphoribosyl-ATP diphosphatase activity
KHA79_08390	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
KHA79_08395	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
KHA79_08400	COG0235	Class ii aldolase
KHA79_08405	COG0531	amino acid
KHA79_08410	COG0531	amino acid
KHA79_08425	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KHA79_08430	COG0277	FAD linked oxidase domain protein
KHA79_08450	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KHA79_08470	COG1024	Enoyl-CoA hydratase
KHA79_08515	COG0348	domain, Protein
KHA79_08525	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KHA79_08535	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
KHA79_08540	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KHA79_08550	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KHA79_08590	COG1136	(ABC) transporter
KHA79_08590	COG0577	efflux transmembrane transporter activity
KHA79_08620	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KHA79_08620	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KHA79_08625	COG1105	Belongs to the carbohydrate kinase PfkB family
KHA79_08630	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KHA79_08630	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
KHA79_08635	COG1609	Transcriptional regulator
KHA79_08645	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
KHA79_08650	COG0069	glutamate synthase activity
KHA79_08660	COG5002	protein histidine kinase activity
KHA79_08660	COG5001	Diguanylate cyclase
KHA79_08660	COG3447	MASE1 domain protein
KHA79_08690	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KHA79_08705	COG1253	flavin adenine dinucleotide binding
KHA79_08735	COG0504	CTP synthase activity
KHA79_08740	COG2877	3-deoxy-8-phosphooctulonate synthase activity
KHA79_08755	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
KHA79_08760	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
KHA79_08775	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
KHA79_08785	COG1238	metal cluster binding
KHA79_08800	COG1534	Rna-binding protein
KHA79_08805	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
KHA79_08810	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KHA79_08815	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KHA79_08830	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KHA79_08835	COG1546	Belongs to the CinA family
KHA79_08840	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
KHA79_08845	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KHA79_08850	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KHA79_08855	COG2137	regulation of response to DNA damage stimulus
KHA79_08860	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KHA79_08865	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
KHA79_08900	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KHA79_08910	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KHA79_08915	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KHA79_08965	COG0438	transferase activity, transferring glycosyl groups
KHA79_08970	COG0438	transferase activity, transferring glycosyl groups
KHA79_08980	COG0438	transferase activity, transferring glycosyl groups
KHA79_09000	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KHA79_09010	COG1960	acyl-CoA dehydrogenase activity
KHA79_09050	COG1570	exodeoxyribonuclease VII activity
KHA79_09055	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KHA79_09060	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KHA79_09060	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
KHA79_09065	COG0802	atpase or kinase
KHA79_09070	COG0860	N-Acetylmuramoyl-L-alanine amidase
KHA79_09075	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KHA79_09095	COG1028	Short-chain dehydrogenase reductase Sdr
KHA79_09115	COG2081	HI0933 family
KHA79_09120	COG4681	YaeQ
KHA79_09125	COG0564	pseudouridine synthase activity
KHA79_09135	COG0625	glutathione transferase activity
KHA79_09140	COG0657	acetylesterase activity
KHA79_09145	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
KHA79_09170	COG0513	Belongs to the DEAD box helicase family
KHA79_09175	COG0488	(ABC) transporter
KHA79_09190	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KHA79_09200	COG1472	Belongs to the glycosyl hydrolase 3 family
KHA79_09240	COG1846	Transcriptional regulator
KHA79_09260	COG0386	Belongs to the glutathione peroxidase family
KHA79_09325	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KHA79_09340	COG0505	Belongs to the CarA family
KHA79_09350	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
KHA79_09355	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KHA79_09400	COG3279	Response regulator of the LytR AlgR family
KHA79_09420	COG0784	Response regulator, receiver
KHA79_09420	COG2198	Histidine kinase
KHA79_09420	COG2205	protein histidine kinase activity
KHA79_09425	COG1024	Enoyl-CoA hydratase
KHA79_09430	COG0318	PFAM AMP-dependent synthetase and ligase
KHA79_09505	COG0840	transmembrane signaling receptor activity
KHA79_09515	COG0835	chemotaxis
KHA79_09525	COG0840	transmembrane signaling receptor activity
KHA79_09540	COG0840	transmembrane signaling receptor activity
KHA79_09555	COG0840	transmembrane signaling receptor activity
KHA79_09565	COG0840	transmembrane signaling receptor activity
KHA79_09580	COG0840	transmembrane signaling receptor activity
KHA79_09595	COG0745	RESPONSE REGULATOR receiver
KHA79_09605	COG0835	chemotaxis
KHA79_09615	COG1360	Flagellar Motor Protein
KHA79_09620	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KHA79_09625	COG2198	Histidine kinase
KHA79_09625	COG0643	Histidine kinase
KHA79_09625	COG0784	Response regulator, receiver
KHA79_09630	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
KHA79_09675	COG1684	flagellar biosynthetic protein fliR
KHA79_09680	COG1987	bacterial-type flagellum assembly
KHA79_09690	COG3190	flagellar
KHA79_09740	COG1677	Flagellar hook-basal body complex protein FliE
KHA79_09780	COG1028	Short-chain dehydrogenase reductase Sdr
KHA79_09785	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KHA79_09805	COG2201	protein-glutamate methylesterase activity
KHA79_09810	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
KHA79_09815	COG2197	response regulator
KHA79_09835	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
KHA79_09840	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KHA79_09845	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KHA79_09850	COG1256	bacterial-type flagellum assembly
KHA79_09850	COG1256	bacterial-type flagellum assembly
KHA79_09850	COG4786	Flagellar basal body rod
KHA79_09850	COG4786	Flagellar basal body rod
KHA79_09865	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
KHA79_09880	COG1749	Flagellar hook protein flgE
KHA79_09890	COG1558	bacterial-type flagellum-dependent cell motility
KHA79_09900	COG0784	Response regulator, receiver
KHA79_09900	COG0835	chemotaxis
KHA79_09945	COG1116	anion transmembrane transporter activity
KHA79_09960	COG2915	High frequency lysogenization protein hflD homolog
KHA79_09965	COG0482	sulfurtransferase activity
KHA79_09985	COG0542	response to heat
KHA79_10005	COG0492	ferredoxin-NADP+ reductase activity
KHA79_10010	COG1674	ftsk spoiiie
KHA79_10030	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KHA79_10035	COG0038	chloride channel
KHA79_10085	COG1595	DNA-templated transcription, initiation
KHA79_10105	COG3038	cytochrome b561
KHA79_10135	COG2244	polysaccharide biosynthetic process
KHA79_10140	COG1215	transferase activity, transferring glycosyl groups
KHA79_10155	COG4106	trans-aconitate 2-methyltransferase activity
KHA79_10165	COG2264	protein methyltransferase activity
KHA79_10170	COG0297	glycogen (starch) synthase activity
KHA79_10175	COG0438	transferase activity, transferring glycosyl groups
KHA79_10195	COG1132	(ABC) transporter
KHA79_10215	COG0512	Glutamine amidotransferase of anthranilate synthase
KHA79_10375	COG1649	PFAM Uncharacterised BCR, COG1649
KHA79_10445	COG2205	protein histidine kinase activity
KHA79_10445	COG0784	Response regulator, receiver
KHA79_10450	COG2183	response to ionizing radiation
KHA79_10455	COG0784	Response regulator, receiver
KHA79_10455	COG4191	Histidine kinase
KHA79_10465	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KHA79_10465	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
KHA79_10485	COG3243	poly(R)-hydroxyalkanoic acid synthase
KHA79_10495	COG1183	phosphatidylcholine synthase activity
KHA79_10500	COG1028	Short-chain dehydrogenase reductase Sdr
KHA79_10525	COG0668	transmembrane transport
KHA79_10530	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
KHA79_10545	COG1914	H( )-stimulated, divalent metal cation uptake system
KHA79_10555	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
KHA79_10560	COG1501	Belongs to the glycosyl hydrolase 31 family
KHA79_10565	COG2207	Transcriptional regulator
KHA79_10575	COG1538	Outer membrane efflux protein
KHA79_10580	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KHA79_10585	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KHA79_10590	COG4773	Receptor
KHA79_10610	COG1487	ribonuclease activity
KHA79_10615	COG4691	Plasmid stability protein
KHA79_10635	COG5599	Phosphatase
KHA79_10650	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KHA79_10680	COG4773	Receptor
KHA79_10685	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KHA79_10685	COG0475	glutathione-regulated potassium exporter activity
KHA79_10690	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KHA79_10700	COG0746	molybdenum cofactor guanylyltransferase activity
KHA79_10710	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KHA79_10720	COG1426	Protein conserved in bacteria
KHA79_10730	COG0820	rRNA (adenine-C2-)-methyltransferase activity
KHA79_10745	COG1024	Enoyl-CoA hydratase
KHA79_10745	COG1250	3-hydroxyacyl-CoA dehydrogenase
KHA79_10750	COG0183	Belongs to the thiolase family
KHA79_10755	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KHA79_10765	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KHA79_10770	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
KHA79_10780	COG0776	regulation of translation
KHA79_10785	COG0539	negative regulation of cytoplasmic translation
KHA79_10790	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
KHA79_10795	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KHA79_10805	COG2957	Belongs to the agmatine deiminase family
KHA79_10810	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KHA79_10850	COG0316	Belongs to the HesB IscA family
KHA79_10850	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
KHA79_10865	COG0428	transporter
KHA79_10870	COG3064	Membrane
KHA79_10880	COG1530	ribonuclease E activity
KHA79_10920	COG1605	Chorismate mutase
KHA79_10920	COG0077	Prephenate dehydratase
KHA79_10925	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KHA79_10930	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KHA79_10970	COG4221	oxidoreductase activity
KHA79_11000	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
KHA79_11035	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
KHA79_11045	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
KHA79_11050	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KHA79_11055	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KHA79_11090	COG0316	Belongs to the HesB IscA family
KHA79_11160	COG0288	reversible hydration of carbon dioxide
KHA79_11165	COG0662	Cupin 2, conserved barrel domain protein
KHA79_11175	COG3844	kynureninase activity
KHA79_11185	COG2925	Exonuclease
KHA79_11225	COG2902	Dehydrogenase
KHA79_11235	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KHA79_11240	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KHA79_11245	COG1960	acyl-CoA dehydrogenase activity
KHA79_11250	COG2226	methyltransferase
KHA79_11255	COG1410	methionine synthase
KHA79_11255	COG0646	methionine synthase
KHA79_11260	COG1410	methionine synthase
KHA79_11260	COG0646	methionine synthase
KHA79_11270	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
KHA79_11270	COG2755	lipolytic protein G-D-S-L family
KHA79_11280	COG2900	Belongs to the SlyX family
KHA79_11295	COG0386	Belongs to the glutathione peroxidase family
KHA79_11305	COG1725	Transcriptional regulator
KHA79_11310	COG1131	(ABC) transporter
KHA79_11350	COG2850	peptidyl-arginine hydroxylation
KHA79_11360	COG0567	Dehydrogenase, E1 component
KHA79_11370	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KHA79_11410	COG1132	(ABC) transporter
KHA79_11420	COG0287	Prephenate dehydrogenase
KHA79_11420	COG1605	Chorismate mutase
KHA79_11425	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
KHA79_11430	COG0484	heat shock protein binding
KHA79_11435	COG0443	Heat shock 70 kDa protein
KHA79_11440	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KHA79_11445	COG1420	regulation of RNA biosynthetic process
KHA79_11450	COG0497	DNA recombination
KHA79_11455	COG0735	belongs to the Fur family
KHA79_11460	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KHA79_11470	COG2867	negative regulation of translational initiation
KHA79_11475	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
KHA79_11480	COG1404	Belongs to the peptidase S8 family
KHA79_11520	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KHA79_11535	COG0583	DNA-binding transcription factor activity
KHA79_11550	COG0415	Belongs to the DNA photolyase family
KHA79_11555	COG0305	Participates in initiation and elongation during chromosome replication
KHA79_11565	COG1960	acyl-CoA dehydrogenase activity
KHA79_11580	COG0084	hydrolase, TatD family'
KHA79_11585	COG2258	MOSC domain
KHA79_11590	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KHA79_11960	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KHA79_11975	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KHA79_11985	COG1663	tetraacyldisaccharide 4'-kinase activity
KHA79_11990	COG1132	(ABC) transporter
KHA79_12000	COG0811	peptide transport
KHA79_12020	COG4591	ABC-type transport system involved in lipoprotein release permease component
KHA79_12035	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KHA79_12045	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
KHA79_12050	COG2009	succinate dehydrogenase
KHA79_12060	COG0354	folic acid binding
KHA79_12065	COG3842	ATPase activity
KHA79_12070	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KHA79_12085	COG0129	dihydroxy-acid dehydratase activity
KHA79_12090	COG0800	Aldolase
KHA79_12100	COG0395	ABC-type sugar transport system, permease component
KHA79_12135	COG2350	Protein conserved in bacteria
KHA79_12140	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KHA79_12145	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KHA79_12150	COG1187	pseudouridine synthase activity
KHA79_12170	COG0436	Aminotransferase
KHA79_12175	COG4133	protoheme IX ABC transporter activity
KHA79_12220	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KHA79_12225	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KHA79_12230	COG4988	ABC transporter
KHA79_12240	COG1294	oxidase, subunit
KHA79_12270	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KHA79_12290	COG0165	Argininosuccinate lyase
KHA79_12295	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KHA79_12305	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
KHA79_12310	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KHA79_12315	COG0137	argininosuccinate synthase activity
KHA79_12320	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KHA79_12335	COG2166	iron-sulfur cluster assembly
KHA79_12340	COG2814	Major facilitator Superfamily
KHA79_12365	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
KHA79_12375	COG4677	pectinesterase activity
KHA79_12400	COG0402	S-adenosylhomocysteine deaminase activity
KHA79_12405	COG3548	integral membrane protein
KHA79_12415	COG1509	lysine 2,3-aminomutase activity
KHA79_12420	COG3706	GGDEF domain
KHA79_12420	COG4251	negative regulation of phosphorylation
KHA79_12420	COG5001	Diguanylate cyclase
KHA79_12420	COG2203	Gaf domain
KHA79_12450	COG1862	Preprotein translocase
KHA79_12460	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KHA79_12470	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KHA79_12480	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KHA79_12485	COG3291	Pkd domain containing protein
KHA79_12490	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KHA79_12495	COG0405	Gamma-glutamyltransferase
KHA79_12500	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
KHA79_12515	COG0742	ribosomal rna small subunit methyltransferase
KHA79_12545	COG4771	TonB-dependent receptor
KHA79_12605	COG0531	amino acid
KHA79_12620	COG0006	proline dipeptidase activity
KHA79_12630	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KHA79_12645	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KHA79_12650	COG3938	Belongs to the proline racemase family
KHA79_12660	COG0552	protein localization to endoplasmic reticulum
KHA79_12710	COG0835	chemotaxis
KHA79_12715	COG0840	transmembrane signaling receptor activity
KHA79_12720	COG0840	transmembrane signaling receptor activity
KHA79_12745	COG5001	Diguanylate cyclase
KHA79_12745	COG3300	MHYT domain
KHA79_12750	COG1185	polyribonucleotide nucleotidyltransferase activity
KHA79_12775	COG0195	Participates in both transcription termination and antitermination
KHA79_12790	COG1007	ATP synthesis coupled electron transport
KHA79_12825	COG1034	ATP synthesis coupled electron transport
KHA79_12830	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
KHA79_12835	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
KHA79_12840	COG0649	NAD binding
KHA79_12845	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KHA79_12855	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KHA79_12885	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KHA79_12925	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KHA79_12940	COG2890	protein-(glutamine-N5) methyltransferase activity
KHA79_12950	COG0688	phosphatidylethanolamine metabolic process
KHA79_12960	COG0433	COG0433 Predicted ATPase
KHA79_12970	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KHA79_12995	COG0717	Belongs to the dCTP deaminase family
KHA79_13000	COG0489	protein tyrosine kinase activity
KHA79_13005	COG4771	TonB-dependent receptor
KHA79_13010	COG4771	TonB-dependent receptor
KHA79_13015	COG0457	Tetratricopeptide repeat
KHA79_13025	COG3590	peptidase
KHA79_13045	COG0697	spore germination
KHA79_13065	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KHA79_13070	COG2311	Membrane
KHA79_13075	COG1047	Peptidyl-prolyl cis-trans
KHA79_13080	COG0791	NLP P60 protein
KHA79_13085	COG0791	NLP P60 protein
KHA79_13100	COG1607	acyl-coa hydrolase
KHA79_13105	COG2226	methyltransferase
KHA79_13110	COG1301	dicarboxylic acid transport
KHA79_13115	COG1785	Belongs to the alkaline phosphatase family
KHA79_13125	COG0037	tRNA processing
KHA79_13130	COG1722	exodeoxyribonuclease VII activity
KHA79_13135	COG0142	geranyltranstransferase activity
KHA79_13150	COG1858	cytochrome C peroxidase
KHA79_13155	COG3852	Histidine kinase
KHA79_13175	COG2815	serine threonine protein kinase
KHA79_13175	COG0515	serine threonine protein kinase
KHA79_13180	COG0631	protein serine/threonine phosphatase activity
KHA79_13275	COG0312	modulator of DNA gyrase
KHA79_13285	COG0312	modulator of DNA gyrase
KHA79_13305	COG2968	Membrane
KHA79_13320	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KHA79_13335	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KHA79_13350	COG0495	leucyl-tRNA aminoacylation
KHA79_13360	COG3118	belongs to the thioredoxin family
KHA79_13375	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
KHA79_13385	COG2040	homocysteine
KHA79_13395	COG0346	lactoylglutathione lyase activity
KHA79_13400	COG1131	(ABC) transporter
KHA79_13425	COG2878	Part of a membrane complex involved in electron transport
KHA79_13440	COG1595	DNA-templated transcription, initiation
KHA79_13465	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KHA79_13485	COG0251	oxidation-reduction process
KHA79_13495	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KHA79_13495	COG0392	lysyltransferase activity
KHA79_13525	COG2814	Major facilitator Superfamily
KHA79_13530	COG1902	pentaerythritol trinitrate reductase activity
KHA79_13535	COG2824	Alkylphosphonate utilization operon protein PhnA
KHA79_13540	COG1047	Peptidyl-prolyl cis-trans
KHA79_13545	COG1077	Cell shape determining protein MreB Mrl
KHA79_13580	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KHA79_13590	COG1451	nucleotide metabolic process
KHA79_13610	COG2205	protein histidine kinase activity
KHA79_13620	COG2186	Transcriptional regulator
KHA79_13625	COG3250	beta-galactosidase activity
KHA79_13670	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
KHA79_13670	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
KHA79_13670	COG1703	isobutyryl-CoA mutase activity
KHA79_13695	COG0183	Belongs to the thiolase family
KHA79_13735	COG1793	dna ligase
KHA79_13735	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
KHA79_13740	COG1793	dna ligase
KHA79_13740	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
KHA79_13745	COG1201	RNA secondary structure unwinding
KHA79_13755	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KHA79_13760	COG1278	Cold shock
KHA79_13765	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
KHA79_13770	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
KHA79_13775	COG1472	Belongs to the glycosyl hydrolase 3 family
KHA79_13780	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KHA79_13785	COG2954	triphosphatase activity
KHA79_13795	COG0745	RESPONSE REGULATOR receiver
KHA79_13800	COG1381	Involved in DNA repair and RecF pathway recombination
KHA79_13805	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KHA79_13825	COG0481	GTPase activity
KHA79_13830	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KHA79_13845	COG1250	3-hydroxyacyl-CoA dehydrogenase
KHA79_13845	COG1024	Enoyl-CoA hydratase
KHA79_13860	COG2855	membrane
KHA79_13935	COG1074	ATP-dependent DNA helicase activity
KHA79_13990	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KHA79_14130	COG1196	nuclear chromosome segregation
KHA79_14240	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KHA79_14260	COG2205	protein histidine kinase activity
KHA79_14265	COG0745	RESPONSE REGULATOR receiver
KHA79_14275	COG2194	sulfuric ester hydrolase activity
KHA79_14295	COG2814	Major facilitator Superfamily
KHA79_14320	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KHA79_14320	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KHA79_14325	COG0753	catalase activity
KHA79_14350	COG1063	alcohol dehydrogenase
KHA79_14360	COG3459	Glycosyltransferase 36 associated
KHA79_14410	COG3177	Filamentation induced by cAMP protein fic
KHA79_14415	COG3586	endonuclease activity
KHA79_14475	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KHA79_14485	COG0330	HflC and HflK could
KHA79_14490	COG0330	HflC and HflK could
KHA79_14495	COG0604	alcohol dehydrogenase
KHA79_14515	COG0678	peroxiredoxin activity
KHA79_14525	COG4953	penicillin-binding protein 1C
KHA79_14545	COG2373	Large extracellular alpha-helical protein
KHA79_14575	COG3609	addiction module antidote protein, CC2985 family
KHA79_14600	COG0372	Belongs to the citrate synthase family
KHA79_14605	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KHA79_14620	COG0587	DNA-directed DNA polymerase activity
KHA79_14660	COG2161	toxin-antitoxin pair type II binding
KHA79_14665	COG4115	mRNA cleavage
KHA79_14685	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KHA79_14690	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KHA79_14695	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KHA79_14705	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KHA79_14710	COG1028	Short-chain dehydrogenase reductase Sdr
KHA79_14715	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KHA79_14720	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KHA79_14725	COG0333	Belongs to the bacterial ribosomal protein bL32 family
KHA79_14730	COG1399	metal-binding, possibly nucleic acid-binding protein
KHA79_14745	COG0714	Associated with various cellular activities
KHA79_14765	COG0537	adenosine 5'-monophosphoramidase activity
KHA79_14815	COG0314	molybdopterin synthase activity
KHA79_14820	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
KHA79_14825	COG0315	cyclic pyranopterin monophosphate synthase activity
KHA79_14835	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KHA79_14840	COG1234	tRNA 3'-trailer cleavage
KHA79_14850	COG0859	PFAM glycosyl transferase family 9
KHA79_14865	COG0631	protein serine/threonine phosphatase activity
KHA79_14875	COG0328	RNA-DNA hybrid ribonuclease activity
KHA79_14885	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KHA79_14890	COG3942	CHAP domain
KHA79_14890	COG1388	LysM domain
KHA79_14925	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KHA79_14935	COG0544	peptidyl-prolyl cis-trans isomerase activity
KHA79_14970	COG0473	3-isopropylmalate dehydrogenase activity
KHA79_14985	COG4783	chaperone-mediated protein folding
KHA79_15000	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KHA79_15005	COG0248	Ppx GppA phosphatase
KHA79_15010	COG0438	transferase activity, transferring glycosyl groups
KHA79_15020	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KHA79_15030	COG3291	Pkd domain containing protein
KHA79_15035	COG3291	Pkd domain containing protein
KHA79_15040	COG2833	Protein of unknown function (DUF455)
KHA79_15060	COG0285	dihydrofolate synthase activity
KHA79_15065	COG0588	phosphoglycerate mutase activity
KHA79_15085	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
KHA79_15090	COG4208	sulfate ABC transporter
KHA79_15095	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
KHA79_15105	COG0156	8-amino-7-oxononanoate synthase activity
KHA79_15110	COG1187	pseudouridine synthase activity
KHA79_15120	COG2885	chlorophyll binding
KHA79_15125	COG0583	DNA-binding transcription factor activity
KHA79_15130	COG2814	Major facilitator Superfamily
KHA79_15140	COG0667	Aldo Keto reductase
KHA79_15150	COG1902	pentaerythritol trinitrate reductase activity
KHA79_15150	COG0446	pyridine nucleotide-disulphide oxidoreductase
KHA79_15175	COG0584	glycerophosphoryl diester phosphodiesterase
KHA79_15195	COG0625	glutathione transferase activity
KHA79_15210	COG0039	L-malate dehydrogenase activity
KHA79_15220	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KHA79_15225	COG1217	gtp-binding protein TYPA
KHA79_15245	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
KHA79_15255	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
KHA79_15260	COG0203	ribosomal protein L17
KHA79_15270	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KHA79_15285	COG0201	protein transport
KHA79_15295	COG1841	ribosomal large subunit assembly
KHA79_15325	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KHA79_15330	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KHA79_15340	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KHA79_15345	COG0255	Belongs to the universal ribosomal protein uL29 family
KHA79_15370	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KHA79_15375	COG0089	rRNA binding
KHA79_15380	COG0088	Forms part of the polypeptide exit tunnel
KHA79_15390	COG0051	transcription antitermination factor activity, RNA binding
KHA79_15395	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KHA79_15400	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KHA79_15415	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KHA79_15425	COG0222	ribosome binding
KHA79_15440	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KHA79_15445	COG0250	Participates in transcription elongation, termination and antitermination
KHA79_15450	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KHA79_15460	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KHA79_15480	COG0012	GTP binding
KHA79_15485	COG0193	aminoacyl-tRNA hydrolase activity
KHA79_15495	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KHA79_15520	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
KHA79_15525	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KHA79_15535	COG5297	Belongs to the glycosyl hydrolase family 6
KHA79_15540	COG0521	Mo-molybdopterin cofactor biosynthetic process
KHA79_15560	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KHA79_15565	COG1295	ribonuclease BN
KHA79_15585	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KHA79_15595	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KHA79_15665	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KHA79_15665	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KHA79_15700	COG2890	protein-(glutamine-N5) methyltransferase activity
KHA79_15710	COG3634	alkyl hydroperoxide reductase activity
KHA79_15715	COG0583	DNA-binding transcription factor activity
KHA79_15725	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KHA79_15730	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KHA79_15735	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KHA79_15765	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KHA79_15770	COG0697	spore germination
KHA79_15810	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KHA79_15815	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KHA79_15825	COG2096	Adenosyltransferase
KHA79_15840	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KHA79_15845	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
KHA79_15850	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KHA79_15855	COG2967	ApaG domain
KHA79_15860	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KHA79_15890	COG1704	LemA family
KHA79_15895	COG0861	Integral membrane protein TerC family
KHA79_15900	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KHA79_15910	COG0642	Histidine kinase
KHA79_15925	COG4181	ATPase activity
KHA79_15930	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
KHA79_15950	COG4771	TonB-dependent receptor
KHA79_15960	COG0667	Aldo Keto reductase
KHA79_15965	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KHA79_15985	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KHA79_16005	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KHA79_16070	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KHA79_16080	COG0494	nUDIX hydrolase
KHA79_16095	COG0739	heme binding
KHA79_16105	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
KHA79_16110	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KHA79_16120	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KHA79_16125	COG1181	Belongs to the D-alanine--D-alanine ligase family
KHA79_16135	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KHA79_16150	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KHA79_16165	COG3116	cell division
KHA79_16170	COG0275	rRNA processing
KHA79_16175	COG2001	Belongs to the MraZ family
KHA79_16200	COG0792	nuclease activity
KHA79_16205	COG0277	FAD linked oxidase domain protein
KHA79_16210	COG0745	RESPONSE REGULATOR receiver
KHA79_16215	COG2205	protein histidine kinase activity
KHA79_16225	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
KHA79_16230	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
KHA79_16255	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
KHA79_16260	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KHA79_16265	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
KHA79_16280	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KHA79_16280	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KHA79_16290	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KHA79_16315	COG0488	(ABC) transporter
KHA79_16320	COG0242	peptide deformylase activity
KHA79_16350	COG1215	transferase activity, transferring glycosyl groups
KHA79_16360	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KHA79_16420	COG2188	Transcriptional regulator
KHA79_16430	COG1450	Type ii and iii secretion system protein
KHA79_16445	COG3166	PFAM Fimbrial assembly family protein
KHA79_16450	COG3156	type II secretion system protein K
KHA79_16455	COG4795	General secretion pathway protein
KHA79_16460	COG2165	general secretion pathway protein
KHA79_16465	COG4970	Tfp pilus assembly protein FimT
KHA79_16470	COG2165	general secretion pathway protein
KHA79_16475	COG1459	type II secretion system
KHA79_16480	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KHA79_16485	COG1404	Belongs to the peptidase S8 family
KHA79_16490	COG5295	Hep Hag repeat protein
KHA79_16500	COG0840	transmembrane signaling receptor activity
KHA79_16505	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KHA79_16505	COG0047	phosphoribosylformylglycinamidine synthase activity
KHA79_16510	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KHA79_16515	COG4974	Belongs to the 'phage' integrase family
KHA79_16540	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KHA79_16575	COG1183	phosphatidylcholine synthase activity
KHA79_16585	COG0442	prolyl-tRNA aminoacylation
KHA79_16600	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
KHA79_16605	COG1127	ABC transporter
KHA79_16610	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
KHA79_16610	COG3218	ABC-type transport auxiliary lipoprotein component
KHA79_16640	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KHA79_16645	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KHA79_16650	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
KHA79_16650	COG0662	Cupin 2, conserved barrel domain protein
KHA79_16675	COG2086	electron transfer activity
KHA79_16690	COG0546	phosphoglycolate phosphatase activity
KHA79_16690	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
KHA79_16695	COG0277	FAD linked oxidase domain protein
KHA79_16700	COG0300	oxidoreductase activity
KHA79_16725	COG0493	'glutamate synthase
KHA79_16760	COG1216	Glycosyl transferase, family 2
KHA79_16760	COG0438	transferase activity, transferring glycosyl groups
KHA79_16765	COG1216	Glycosyl transferase, family 2
KHA79_16765	COG0438	transferase activity, transferring glycosyl groups
KHA79_16770	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KHA79_16785	COG0626	cystathionine gamma-synthase activity
KHA79_16815	COG0625	glutathione transferase activity
KHA79_16825	COG0513	Belongs to the DEAD box helicase family
KHA79_16830	COG0720	synthase
KHA79_16840	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
KHA79_16845	COG1956	GAF domain-containing protein
KHA79_16855	COG4206	TonB-dependent receptor
KHA79_16900	COG0339	signal peptide processing
KHA79_16905	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KHA79_16915	COG2217	Heavy metal translocating P-type atpase
KHA79_16930	COG2132	Multicopper oxidase
KHA79_16945	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KHA79_16970	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KHA79_16985	COG0355	proton-transporting ATP synthase activity, rotational mechanism
KHA79_17000	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KHA79_17010	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KHA79_17020	COG0356	it plays a direct role in the translocation of protons across the membrane
KHA79_17035	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KHA79_17040	COG0508	dehydrogenase complex catalyzes the overall conversion of
KHA79_17070	COG2011	ABC-type metal ion transport system permease component
KHA79_17075	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KHA79_17080	COG0697	spore germination
KHA79_17085	COG1666	GTP binding
KHA79_17095	COG1187	pseudouridine synthase activity
KHA79_17120	COG2205	protein histidine kinase activity
KHA79_17120	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KHA79_17145	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KHA79_17215	COG0842	Transport permease protein
KHA79_17220	COG1131	(ABC) transporter
KHA79_17225	COG0025	NhaP-type Na H and K H
KHA79_17235	COG1573	uracil-dna glycosylase
KHA79_17250	COG3384	dioxygenase
KHA79_17255	COG0583	DNA-binding transcription factor activity
KHA79_17265	COG0667	Aldo Keto reductase
KHA79_17300	COG3706	GGDEF domain
KHA79_17310	COG5001	Diguanylate cyclase
KHA79_17340	COG4106	trans-aconitate 2-methyltransferase activity
KHA79_17350	COG2076	Multidrug Resistance protein
KHA79_17360	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KHA79_17390	COG3279	Response regulator of the LytR AlgR family
KHA79_17395	COG3275	phosphorelay sensor kinase activity
KHA79_17400	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
KHA79_17420	COG0531	amino acid
KHA79_17430	COG5297	Belongs to the glycosyl hydrolase family 6
KHA79_17430	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
KHA79_17435	COG0612	Peptidase, M16
KHA79_17445	COG0741	lytic transglycosylase activity
KHA79_17460	COG2207	Transcriptional regulator
KHA79_17470	COG0598	Magnesium transport protein CorA
KHA79_17475	COG1113	amino acid transport
KHA79_17480	COG0697	spore germination
KHA79_17495	COG2249	NAD(P)H dehydrogenase (quinone) activity
KHA79_17515	COG5520	Belongs to the glycosyl hydrolase 30 family
KHA79_17600	COG2131	deaminase
KHA79_17620	COG0840	transmembrane signaling receptor activity
KHA79_17655	COG2353	YceI-like domain
KHA79_17685	COG0584	glycerophosphoryl diester phosphodiesterase
KHA79_17695	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
KHA79_17715	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KHA79_17720	COG0459	protein refolding
KHA79_17735	COG1324	tolerance protein
KHA79_17745	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KHA79_17755	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
KHA79_17760	COG0511	ligase activity, forming carbon-carbon bonds
KHA79_17765	COG0439	Biotin carboxylase
KHA79_17780	COG2264	protein methyltransferase activity
KHA79_17800	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
KHA79_17805	COG4589	Belongs to the CDS family
KHA79_17820	COG0138	bifunctional purine biosynthesis protein purh
KHA79_17825	COG0151	Belongs to the GarS family
KHA79_17830	COG1289	transmembrane transporter activity
KHA79_17835	COG2814	Major facilitator Superfamily
KHA79_17870	COG2816	NAD+ diphosphatase activity
KHA79_17910	COG2906	2 iron, 2 sulfur cluster binding
KHA79_17940	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
KHA79_17955	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KHA79_17960	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KHA79_17965	COG0730	response to heat
KHA79_17975	COG0134	indole-3-glycerol-phosphate synthase activity
KHA79_17980	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KHA79_18000	COG1597	lipid kinase activity
KHA79_18015	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
KHA79_18035	COG2111	Na H antiporter
KHA79_18035	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KHA79_18040	COG1006	Multisubunit Na H antiporter MnhC subunit
KHA79_18045	COG0651	ATP synthesis coupled electron transport
KHA79_18055	COG2212	antiporter activity
KHA79_18060	COG1320	monovalent cation:proton antiporter activity
KHA79_18065	COG0530	calcium, potassium:sodium antiporter activity
KHA79_18080	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
KHA79_18085	COG2852	Protein conserved in bacteria
KHA79_18105	COG3104	oligopeptide transport
KHA79_18110	COG3483	tryptophan 2,3-dioxygenase activity
KHA79_18120	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KHA79_18135	COG0508	dehydrogenase complex catalyzes the overall conversion of
KHA79_18150	COG0513	Belongs to the DEAD box helicase family
KHA79_18170	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KHA79_18180	COG2354	Protein conserved in bacteria
KHA79_18200	COG1196	nuclear chromosome segregation
KHA79_18200	COG3264	Mechanosensitive ion channel
KHA79_18205	COG3321	synthase
KHA79_18205	COG1028	Short-chain dehydrogenase reductase Sdr
KHA79_18205	COG0604	alcohol dehydrogenase
KHA79_18225	COG1595	DNA-templated transcription, initiation
KHA79_18240	COG1802	Transcriptional regulator
KHA79_18290	COG1414	Transcriptional regulator
KHA79_18295	COG0738	Major facilitator superfamily
KHA79_18300	COG3254	rhamnose metabolic process
KHA79_18305	COG4948	Mandelate Racemase Muconate Lactonizing
KHA79_18310	COG0179	Fumarylacetoacetate (FAA) hydrolase
KHA79_18315	COG1028	Short-chain dehydrogenase reductase Sdr
KHA79_18345	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KHA79_18360	COG4807	Protein conserved in bacteria
KHA79_18390	COG0823	Involved in the tonB-independent uptake of proteins
KHA79_18390	COG1506	peptidase
KHA79_18490	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KHA79_18515	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KHA79_18520	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KHA79_18530	COG0753	catalase activity
KHA79_18550	COG1136	(ABC) transporter
KHA79_18555	COG0577	efflux transmembrane transporter activity
KHA79_18575	COG0697	spore germination
KHA79_18580	COG0564	pseudouridine synthase activity
KHA79_18600	COG1181	Belongs to the D-alanine--D-alanine ligase family
KHA79_18610	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KHA79_18625	COG0318	PFAM AMP-dependent synthetase and ligase
KHA79_18630	COG0727	PFAM Uncharacterised protein family (UPF0153)
KHA79_18640	COG0596	Alpha beta hydrolase
KHA79_18655	COG3177	Filamentation induced by cAMP protein fic
KHA79_18660	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KHA79_18670	COG0612	Peptidase, M16
KHA79_18680	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KHA79_18810	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KHA79_18820	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
KHA79_18825	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
KHA79_18860	COG0183	Belongs to the thiolase family
KHA79_18870	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KHA79_18875	COG3387	PFAM Glycoside hydrolase 15-related
KHA79_18880	COG0745	RESPONSE REGULATOR receiver
KHA79_18895	COG1404	Belongs to the peptidase S8 family
KHA79_18905	COG3100	YcgL domain-containing protein
KHA79_18910	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KHA79_18920	COG0463	Glycosyl transferase, family 2
KHA79_18955	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KHA79_18970	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KHA79_18990	COG3179	chitinase
KHA79_19020	COG1294	oxidase, subunit
KHA79_19025	COG1271	oxidase subunit
KHA79_19040	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KHA79_19045	COG0408	coproporphyrinogen oxidase activity
KHA79_19055	COG2323	membrane
KHA79_19080	COG0589	response to stress
KHA79_19095	COG0210	DNA helicase
KHA79_19145	COG0463	Glycosyl transferase, family 2
KHA79_19160	COG1192	Involved in chromosome partitioning
KHA79_19165	COG0357	Ribosomal RNA small subunit methyltransferase G
KHA79_19170	COG3540	Alkaline phosphatase
KHA79_19175	COG2091	lysine biosynthetic process via aminoadipic acid
KHA79_19200	COG0477	Major facilitator Superfamily
KHA79_19220	COG1971	Probably functions as a manganese efflux pump
KHA79_19225	COG2205	protein histidine kinase activity
KHA79_19240	COG3459	Glycosyltransferase 36 associated
KHA79_19245	COG2211	Major facilitator Superfamily
KHA79_19250	COG3265	gluconokinase activity
KHA79_19265	COG2911	Protein conserved in bacteria
KHA79_19270	COG0729	surface antigen
KHA79_19290	COG3132	Protein of unknown function, DUF480
KHA79_19345	COG0284	orotidine-5'-phosphate decarboxylase activity
KHA79_19370	COG2937	Belongs to the GPAT DAPAT family
KHA79_19395	COG2211	Major facilitator Superfamily
KHA79_19405	COG3693	PFAM glycoside hydrolase, family 10
KHA79_19415	COG3386	PFAM SMP-30 Gluconolaconase
KHA79_19425	COG0246	Mannitol dehydrogenase
KHA79_19430	COG1472	Belongs to the glycosyl hydrolase 3 family
KHA79_19435	COG3507	Belongs to the glycosyl hydrolase 43 family
KHA79_19450	COG2115	Belongs to the xylose isomerase family
KHA79_19475	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KHA79_19485	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KHA79_19495	COG0805	protein transport
KHA79_19505	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KHA79_19505	COG0519	Catalyzes the synthesis of GMP from XMP
KHA79_19510	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KHA79_19525	COG0210	DNA helicase
KHA79_19530	COG1435	thymidine kinase activity
KHA79_19540	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
KHA79_19550	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
KHA79_19565	COG1119	ATPase activity
KHA79_19585	COG0594	ribonuclease P activity