locus-tag	class	description
KFS84_00010	COG0592	DNA-directed DNA polymerase activity
KFS84_00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KFS84_00020	COG0187	DNA topoisomerase II activity
KFS84_00025	COG1266	CAAX protease self-immunity
KFS84_00030	COG0501	Belongs to the peptidase M48B family
KFS84_00060	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
KFS84_00070	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KFS84_00115	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KFS84_00130	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KFS84_00135	COG3387	PFAM Glycoside hydrolase 15-related
KFS84_00140	COG0745	RESPONSE REGULATOR receiver
KFS84_00155	COG1404	Belongs to the peptidase S8 family
KFS84_00165	COG3100	YcgL domain-containing protein
KFS84_00170	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KFS84_00180	COG0463	Glycosyl transferase, family 2
KFS84_00190	COG1028	Short-chain dehydrogenase reductase Sdr
KFS84_00220	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KFS84_00235	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KFS84_00250	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
KFS84_00260	COG1294	oxidase, subunit
KFS84_00265	COG1271	oxidase subunit
KFS84_00280	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KFS84_00285	COG0408	coproporphyrinogen oxidase activity
KFS84_00320	COG2323	membrane
KFS84_00330	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KFS84_00330	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KFS84_00345	COG0589	response to stress
KFS84_00375	COG0210	DNA helicase
KFS84_00445	COG0463	Glycosyl transferase, family 2
KFS84_00455	COG1475	DNA binding
KFS84_00460	COG1192	Involved in chromosome partitioning
KFS84_00465	COG0357	Ribosomal RNA small subunit methyltransferase G
KFS84_00470	COG3540	Alkaline phosphatase
KFS84_00485	COG2091	lysine biosynthetic process via aminoadipic acid
KFS84_00510	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KFS84_00575	COG3279	Response regulator of the LytR AlgR family
KFS84_00580	COG3275	phosphorelay sensor kinase activity
KFS84_00605	COG0531	amino acid
KFS84_00615	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
KFS84_00615	COG5297	Belongs to the glycosyl hydrolase family 6
KFS84_00620	COG0612	Peptidase, M16
KFS84_00650	COG2264	protein methyltransferase activity
KFS84_00675	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
KFS84_00695	COG4589	Belongs to the CDS family
KFS84_00715	COG2267	carboxylic ester hydrolase activity
KFS84_00720	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KFS84_00725	COG0138	bifunctional purine biosynthesis protein purh
KFS84_00735	COG0151	Belongs to the GarS family
KFS84_00760	COG0339	signal peptide processing
KFS84_00765	COG0681	Belongs to the peptidase S26 family
KFS84_00785	COG0583	DNA-binding transcription factor activity
KFS84_00790	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
KFS84_00795	COG2224	Isocitrate lyase
KFS84_00800	COG3706	GGDEF domain
KFS84_00835	COG0659	secondary active sulfate transmembrane transporter activity
KFS84_00865	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KFS84_00870	COG2130	NADP-dependent
KFS84_00875	COG0667	Aldo Keto reductase
KFS84_00885	COG1187	pseudouridine synthase activity
KFS84_00905	COG1666	GTP binding
KFS84_00910	COG0697	spore germination
KFS84_00915	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KFS84_00955	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KFS84_00990	COG0180	Tryptophanyl-tRNA synthetase
KFS84_01000	COG3237	CsbD-like
KFS84_01030	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
KFS84_01035	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
KFS84_01035	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
KFS84_01085	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KFS84_01130	COG2084	Dehydrogenase
KFS84_01135	COG1902	pentaerythritol trinitrate reductase activity
KFS84_01150	COG2814	Major facilitator Superfamily
KFS84_01155	COG0583	DNA-binding transcription factor activity
KFS84_01185	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KFS84_01190	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KFS84_01195	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KFS84_01210	COG2911	Protein conserved in bacteria
KFS84_01215	COG0729	surface antigen
KFS84_01235	COG3132	Protein of unknown function, DUF480
KFS84_01265	COG0523	cobalamin synthesis protein
KFS84_01275	COG1742	UPF0060 membrane protein
KFS84_01285	COG3245	cytochrome
KFS84_01295	COG1960	acyl-CoA dehydrogenase activity
KFS84_01300	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KFS84_01345	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
KFS84_01355	COG0697	spore germination
KFS84_01370	COG3459	Glycosyltransferase 36 associated
KFS84_01400	COG2906	2 iron, 2 sulfur cluster binding
KFS84_01405	COG1051	belongs to the nudix hydrolase family
KFS84_01430	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
KFS84_01445	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KFS84_01450	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KFS84_01455	COG0730	response to heat
KFS84_01460	COG4124	Belongs to the glycosyl hydrolase 26 family
KFS84_01460	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
KFS84_01470	COG0134	indole-3-glycerol-phosphate synthase activity
KFS84_01475	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KFS84_01495	COG1597	lipid kinase activity
KFS84_01510	COG0484	heat shock protein binding
KFS84_01525	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KFS84_01530	COG2111	Na H antiporter
KFS84_01530	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KFS84_01535	COG1006	Multisubunit Na H antiporter MnhC subunit
KFS84_01540	COG0651	ATP synthesis coupled electron transport
KFS84_01550	COG2212	antiporter activity
KFS84_01555	COG1320	monovalent cation:proton antiporter activity
KFS84_01565	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
KFS84_01590	COG2264	protein methyltransferase activity
KFS84_01615	COG1971	Probably functions as a manganese efflux pump
KFS84_01620	COG2205	protein histidine kinase activity
KFS84_01630	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KFS84_01670	COG2816	NAD+ diphosphatase activity
KFS84_01745	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KFS84_01760	COG5001	Diguanylate cyclase
KFS84_01790	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KFS84_01795	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KFS84_01805	COG0667	Aldo Keto reductase
KFS84_01810	COG0667	Aldo Keto reductase
KFS84_01830	COG3384	dioxygenase
KFS84_01845	COG1573	uracil-dna glycosylase
KFS84_01850	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
KFS84_01860	COG0025	NhaP-type Na H and K H
KFS84_01865	COG1131	(ABC) transporter
KFS84_01870	COG0842	Transport permease protein
KFS84_01910	COG4206	TonB-dependent receptor
KFS84_01920	COG1956	GAF domain-containing protein
KFS84_01925	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
KFS84_01935	COG0720	synthase
KFS84_01940	COG0513	Belongs to the DEAD box helicase family
KFS84_01950	COG0625	glutathione transferase activity
KFS84_01980	COG1643	Atp-dependent helicase
KFS84_01985	COG0084	hydrolase, TatD family'
KFS84_02025	COG0842	Transport permease protein
KFS84_02030	COG1131	(ABC) transporter
KFS84_02035	COG0543	2 iron, 2 sulfur cluster binding
KFS84_02035	COG0633	Ferredoxin
KFS84_02045	COG1476	TRANSCRIPTIONal
KFS84_02055	COG4555	ABC transporter
KFS84_02080	COG0625	glutathione transferase activity
KFS84_02185	COG1199	ATP-dependent helicase activity
KFS84_02225	COG0628	permease
KFS84_02245	COG0129	dihydroxy-acid dehydratase activity
KFS84_02250	COG2133	pyrroloquinoline quinone binding
KFS84_02290	COG5463	Belongs to the UPF0441 family
KFS84_02295	COG0754	glutathionylspermidine amidase activity
KFS84_02370	COG2831	hemolysin activation secretion protein
KFS84_02380	COG0714	Associated with various cellular activities
KFS84_02415	COG1522	sequence-specific DNA binding
KFS84_02420	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KFS84_02435	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KFS84_02440	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KFS84_02465	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KFS84_02490	COG1028	Short-chain dehydrogenase reductase Sdr
KFS84_02500	COG0156	8-amino-7-oxononanoate synthase activity
KFS84_02505	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
KFS84_02515	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KFS84_02535	COG2267	carboxylic ester hydrolase activity
KFS84_02635	COG2960	long-chain fatty acid transporting porin activity
KFS84_02660	COG1166	arginine decarboxylase activity
KFS84_02685	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KFS84_02715	COG2205	protein histidine kinase activity
KFS84_02715	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KFS84_02790	COG1187	pseudouridine synthase activity
KFS84_02850	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
KFS84_02865	COG3507	Belongs to the glycosyl hydrolase 43 family
KFS84_02885	COG1028	Short-chain dehydrogenase reductase Sdr
KFS84_02900	COG3186	Phenylalanine-4-hydroxylase
KFS84_02905	COG1522	sequence-specific DNA binding
KFS84_02920	COG1752	Esterase of the alpha-beta hydrolase superfamily
KFS84_02940	COG0671	phosphoesterase, PA-phosphatase related
KFS84_02955	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KFS84_02990	COG1929	Belongs to the glycerate kinase type-1 family
KFS84_03000	COG0531	amino acid
KFS84_03005	COG4566	intracellular signal transduction
KFS84_03010	COG4191	Histidine kinase
KFS84_03015	COG1285	pathogenesis
KFS84_03030	COG1322	Protein conserved in bacteria
KFS84_03045	COG1360	Flagellar Motor Protein
KFS84_03080	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KFS84_03085	COG1819	glycosyl
KFS84_03090	COG2755	lipolytic protein G-D-S-L family
KFS84_03090	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
KFS84_03095	COG0583	DNA-binding transcription factor activity
KFS84_03115	COG4221	oxidoreductase activity
KFS84_03135	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KFS84_03145	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KFS84_03160	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KFS84_03170	COG2814	Major facilitator Superfamily
KFS84_03185	COG0739	heme binding
KFS84_03190	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KFS84_03225	COG1064	alcohol dehydrogenase
KFS84_03230	COG2234	aminopeptidase activity
KFS84_03240	COG4942	peptidase
KFS84_03245	COG0793	Belongs to the peptidase S41A family
KFS84_03285	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
KFS84_03285	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
KFS84_03310	COG1565	acr, cog1565
KFS84_03310	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KFS84_03315	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KFS84_03320	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
KFS84_03325	COG1845	cytochrome c oxidase, subunit III
KFS84_03350	COG0109	protoheme IX farnesyltransferase activity
KFS84_03370	COG0358	DNA primase activity
KFS84_03375	COG1295	ribonuclease BN
KFS84_03395	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KFS84_03400	COG2308	Evidence 4 Homologs of previously reported genes of
KFS84_03415	COG2133	pyrroloquinoline quinone binding
KFS84_03455	COG0531	amino acid
KFS84_03465	COG4948	Mandelate Racemase Muconate Lactonizing
KFS84_03475	COG4771	TonB-dependent receptor
KFS84_03530	COG5383	Protein conserved in bacteria
KFS84_03555	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KFS84_03560	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KFS84_03585	COG1652	LysM domain
KFS84_03595	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KFS84_03600	COG1518	maintenance of DNA repeat elements
KFS84_03670	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KFS84_03675	COG3118	belongs to the thioredoxin family
KFS84_03685	COG2884	Cell division ATP-binding protein ftsE
KFS84_03690	COG2177	Part of the ABC transporter FtsEX involved in
KFS84_03695	COG2201	protein-glutamate methylesterase activity
KFS84_03700	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KFS84_03705	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KFS84_03725	COG1252	NADH dehydrogenase
KFS84_03735	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KFS84_03750	COG0534	Mate efflux family protein
KFS84_03755	COG0616	signal peptide processing
KFS84_03765	COG1028	Short-chain dehydrogenase reductase Sdr
KFS84_03805	COG2010	Cytochrome c
KFS84_03815	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
KFS84_03835	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KFS84_03840	COG1077	Cell shape determining protein MreB Mrl
KFS84_03845	COG1792	Involved in formation and maintenance of cell shape
KFS84_03855	COG0768	penicillin binding
KFS84_03860	COG0772	Belongs to the SEDS family
KFS84_03875	COG2951	lytic endotransglycosylase activity
KFS84_03885	COG1686	Belongs to the peptidase S11 family
KFS84_03900	COG0321	lipoyl(octanoyl) transferase activity
KFS84_03905	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KFS84_03930	COG1056	cytidyltransferase-related domain
KFS84_03930	COG1051	belongs to the nudix hydrolase family
KFS84_03985	COG1090	epimerase
KFS84_04000	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
KFS84_04010	COG2823	Periplasmic or secreted lipoprotein
KFS84_04020	COG2205	protein histidine kinase activity
KFS84_04020	COG2202	Pas domain
KFS84_04025	COG0784	Response regulator, receiver
KFS84_04030	COG4191	Histidine kinase
KFS84_04040	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KFS84_04045	COG1028	Short-chain dehydrogenase reductase Sdr
KFS84_04060	COG4305	rare lipoprotein A
KFS84_04070	COG3250	beta-galactosidase activity
KFS84_04085	COG2188	Transcriptional regulator
KFS84_04095	COG1609	Transcriptional regulator
KFS84_04100	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KFS84_04105	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KFS84_04170	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KFS84_04195	COG2207	Transcriptional regulator
KFS84_04220	COG2205	protein histidine kinase activity
KFS84_04235	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
KFS84_04240	COG3791	Glutathione-dependent formaldehyde-activating
KFS84_04255	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KFS84_04265	COG0697	spore germination
KFS84_04290	COG1307	EDD domain protein, DegV family
KFS84_04305	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
KFS84_04325	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
KFS84_04350	COG0436	Aminotransferase
KFS84_04380	COG1162	GTPase activity
KFS84_04410	COG2211	Major facilitator Superfamily
KFS84_04420	COG1028	Short-chain dehydrogenase reductase Sdr
KFS84_04425	COG2851	Citrate transporter
KFS84_04440	COG0642	Histidine kinase
KFS84_04480	COG4191	Histidine kinase
KFS84_04495	COG1301	dicarboxylic acid transport
KFS84_04500	COG0280	phosphate acetyltransferase
KFS84_04500	COG0281	malic enzyme
KFS84_04560	COG1560	Kdo2-lipid A biosynthetic process
KFS84_04565	COG1519	Transferase
KFS84_04570	COG1538	Outer membrane efflux protein
KFS84_04575	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
KFS84_04585	COG3706	GGDEF domain
KFS84_04590	COG0473	3-isopropylmalate dehydrogenase activity
KFS84_04595	COG0066	3-isopropylmalate dehydratase activity
KFS84_04615	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KFS84_04635	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KFS84_04640	COG0840	transmembrane signaling receptor activity
KFS84_04670	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
KFS84_04680	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
KFS84_04705	COG0563	adenylate kinase activity
KFS84_04725	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KFS84_04735	COG0671	phosphoesterase, PA-phosphatase related
KFS84_04755	COG1940	carbohydrate kinase activity
KFS84_04765	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KFS84_04795	COG0521	Mo-molybdopterin cofactor biosynthetic process
KFS84_04800	COG5297	Belongs to the glycosyl hydrolase family 6
KFS84_04815	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KFS84_04820	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
KFS84_04845	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KFS84_04855	COG0193	aminoacyl-tRNA hydrolase activity
KFS84_04860	COG0012	GTP binding
KFS84_04880	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KFS84_04890	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KFS84_04895	COG0250	Participates in transcription elongation, termination and antitermination
KFS84_04900	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KFS84_04915	COG0222	ribosome binding
KFS84_04925	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KFS84_04940	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KFS84_04945	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KFS84_04950	COG0051	transcription antitermination factor activity, RNA binding
KFS84_04960	COG0088	Forms part of the polypeptide exit tunnel
KFS84_04965	COG0089	rRNA binding
KFS84_04970	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KFS84_04995	COG0255	Belongs to the universal ribosomal protein uL29 family
KFS84_05000	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KFS84_05010	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KFS84_05015	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KFS84_05045	COG1841	ribosomal large subunit assembly
KFS84_05055	COG0201	protein transport
KFS84_05080	COG0203	ribosomal protein L17
KFS84_05085	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
KFS84_05105	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
KFS84_05130	COG1217	gtp-binding protein TYPA
KFS84_05135	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KFS84_05145	COG0039	L-malate dehydrogenase activity
KFS84_05160	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KFS84_05170	COG0625	glutathione transferase activity
KFS84_05220	COG0604	alcohol dehydrogenase
KFS84_05225	COG0667	Aldo Keto reductase
KFS84_05235	COG2814	Major facilitator Superfamily
KFS84_05240	COG0583	DNA-binding transcription factor activity
KFS84_05245	COG2885	chlorophyll binding
KFS84_05275	COG0156	8-amino-7-oxononanoate synthase activity
KFS84_05280	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
KFS84_05285	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
KFS84_05290	COG4208	sulfate ABC transporter
KFS84_05295	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
KFS84_05315	COG0588	phosphoglycerate mutase activity
KFS84_05325	COG0285	dihydrofolate synthase activity
KFS84_05345	COG2833	Protein of unknown function (DUF455)
KFS84_05355	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KFS84_05365	COG0438	transferase activity, transferring glycosyl groups
KFS84_05370	COG0248	Ppx GppA phosphatase
KFS84_05375	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KFS84_05390	COG4783	chaperone-mediated protein folding
KFS84_05405	COG0473	3-isopropylmalate dehydrogenase activity
KFS84_05465	COG0544	peptidyl-prolyl cis-trans isomerase activity
KFS84_05475	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KFS84_05505	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KFS84_05515	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KFS84_05525	COG0328	RNA-DNA hybrid ribonuclease activity
KFS84_05530	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KFS84_05535	COG0631	protein serine/threonine phosphatase activity
KFS84_05555	COG0859	PFAM glycosyl transferase family 9
KFS84_05565	COG1234	tRNA 3'-trailer cleavage
KFS84_05570	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KFS84_05580	COG0315	cyclic pyranopterin monophosphate synthase activity
KFS84_05585	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
KFS84_05590	COG0314	molybdopterin synthase activity
KFS84_05650	COG2003	Belongs to the UPF0758 family
KFS84_05740	COG0537	adenosine 5'-monophosphoramidase activity
KFS84_05785	COG1399	metal-binding, possibly nucleic acid-binding protein
KFS84_05790	COG0333	Belongs to the bacterial ribosomal protein bL32 family
KFS84_05795	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KFS84_05800	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KFS84_05805	COG1028	Short-chain dehydrogenase reductase Sdr
KFS84_05810	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KFS84_05820	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KFS84_05825	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KFS84_05830	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KFS84_05880	COG0587	DNA-directed DNA polymerase activity
KFS84_05895	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KFS84_05900	COG0372	Belongs to the citrate synthase family
KFS84_05925	COG3609	addiction module antidote protein, CC2985 family
KFS84_05960	COG2373	Large extracellular alpha-helical protein
KFS84_05990	COG4953	penicillin-binding protein 1C
KFS84_06010	COG0330	HflC and HflK could
KFS84_06015	COG0330	HflC and HflK could
KFS84_06020	COG0604	alcohol dehydrogenase
KFS84_06040	COG0678	peroxiredoxin activity
KFS84_06065	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KFS84_06170	COG3275	phosphorelay sensor kinase activity
KFS84_06200	COG0492	ferredoxin-NADP+ reductase activity
KFS84_06245	COG3459	Glycosyltransferase 36 associated
KFS84_06255	COG1063	alcohol dehydrogenase
KFS84_06285	COG0753	catalase activity
KFS84_06290	COG2203	Gaf domain
KFS84_06290	COG3706	GGDEF domain
KFS84_06290	COG4251	negative regulation of phosphorylation
KFS84_06290	COG5001	Diguanylate cyclase
KFS84_06325	COG2814	Major facilitator Superfamily
KFS84_06345	COG2194	sulfuric ester hydrolase activity
KFS84_06355	COG0745	RESPONSE REGULATOR receiver
KFS84_06360	COG2205	protein histidine kinase activity
KFS84_06380	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
KFS84_06385	COG2894	cell division
KFS84_06390	COG0850	regulation of cytokinetic process
KFS84_06400	COG4585	Histidine kinase
KFS84_06425	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KFS84_06445	COG1216	Glycosyl transferase, family 2
KFS84_06450	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KFS84_06480	COG0189	ligase activity
KFS84_06555	COG0457	Tetratricopeptide repeat
KFS84_06560	COG4771	TonB-dependent receptor
KFS84_06565	COG4771	TonB-dependent receptor
KFS84_06570	COG0489	protein tyrosine kinase activity
KFS84_06575	COG0717	Belongs to the dCTP deaminase family
KFS84_06600	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KFS84_06615	COG0494	nUDIX hydrolase
KFS84_06625	COG0433	COG0433 Predicted ATPase
KFS84_06630	COG0741	lytic transglycosylase activity
KFS84_06635	COG0688	phosphatidylethanolamine metabolic process
KFS84_06645	COG2890	protein-(glutamine-N5) methyltransferase activity
KFS84_06680	COG3853	Toxic anion resistance protein (TelA)
KFS84_06710	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KFS84_06740	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KFS84_06750	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KFS84_06755	COG0649	NAD binding
KFS84_06760	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
KFS84_06765	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
KFS84_06770	COG1034	ATP synthesis coupled electron transport
KFS84_06805	COG1007	ATP synthesis coupled electron transport
KFS84_06820	COG0195	Participates in both transcription termination and antitermination
KFS84_06855	COG1185	polyribonucleotide nucleotidyltransferase activity
KFS84_06865	COG5001	Diguanylate cyclase
KFS84_06865	COG3300	MHYT domain
KFS84_06875	COG1201	RNA secondary structure unwinding
KFS84_06880	COG0840	transmembrane signaling receptor activity
KFS84_06885	COG0840	transmembrane signaling receptor activity
KFS84_06890	COG0835	chemotaxis
KFS84_06955	COG1194	a g-specific adenine glycosylase
KFS84_06960	COG0552	protein localization to endoplasmic reticulum
KFS84_06970	COG3938	Belongs to the proline racemase family
KFS84_06975	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KFS84_06990	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KFS84_07000	COG0006	proline dipeptidase activity
KFS84_07015	COG0531	amino acid
KFS84_07025	COG1472	Belongs to the glycosyl hydrolase 3 family
KFS84_07035	COG3525	Glycosyl hydrolase, family 20, catalytic domain
KFS84_07040	COG1388	LysM domain
KFS84_07040	COG3858	chitin binding
KFS84_07055	COG0837	glucose binding
KFS84_07100	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KFS84_07110	COG0494	nUDIX hydrolase
KFS84_07115	COG1218	3'(2'),5'-bisphosphate nucleotidase
KFS84_07120	COG3956	TIGRFAM MazG family protein
KFS84_07125	COG1742	UPF0060 membrane protein
KFS84_07130	COG0330	HflC and HflK could
KFS84_07165	COG0697	spore germination
KFS84_07195	COG2124	cytochrome p450
KFS84_07200	COG2124	cytochrome p450
KFS84_07205	COG2124	cytochrome p450
KFS84_07210	COG1141	Ferredoxin
KFS84_07215	COG1028	Short-chain dehydrogenase reductase Sdr
KFS84_07220	COG2124	cytochrome p450
KFS84_07225	COG0142	geranyltranstransferase activity
KFS84_07230	COG1657	PFAM Prenyltransferase squalene oxidase
KFS84_07240	COG1304	FMN binding
KFS84_07255	COG1309	transcriptional regulator
KFS84_07275	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KFS84_07280	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KFS84_07285	COG0463	Glycosyl transferase, family 2
KFS84_07290	COG0517	IMP dehydrogenase activity
KFS84_07295	COG2982	Protein involved in outer membrane biogenesis
KFS84_07300	COG1272	protein, Hemolysin III
KFS84_07305	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KFS84_07310	COG0739	heme binding
KFS84_07315	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KFS84_07320	COG0626	cystathionine gamma-synthase activity
KFS84_07325	COG0460	homoserine dehydrogenase
KFS84_07325	COG0527	aspartate kinase activity
KFS84_07330	COG2267	carboxylic ester hydrolase activity
KFS84_07340	COG1760	l-serine dehydratase
KFS84_07355	COG3038	cytochrome b561
KFS84_07385	COG0477	Major facilitator Superfamily
KFS84_07395	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KFS84_07405	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KFS84_07425	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KFS84_07495	COG0519	Catalyzes the synthesis of GMP from XMP
KFS84_07510	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KFS84_07540	COG0840	transmembrane signaling receptor activity
KFS84_07550	COG1113	amino acid transport
KFS84_07630	COG3507	Belongs to the glycosyl hydrolase 43 family
KFS84_07670	COG4771	TonB-dependent receptor
KFS84_07680	COG3345	alpha-galactosidase
KFS84_07700	COG0742	ribosomal rna small subunit methyltransferase
KFS84_07715	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
KFS84_07720	COG0405	Gamma-glutamyltransferase
KFS84_07740	COG0644	oxidoreductase
KFS84_07780	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KFS84_07785	COG3291	Pkd domain containing protein
KFS84_07790	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KFS84_07800	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KFS84_07810	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KFS84_07820	COG1862	Preprotein translocase
KFS84_07855	COG5001	Diguanylate cyclase
KFS84_07855	COG4251	negative regulation of phosphorylation
KFS84_07855	COG2203	Gaf domain
KFS84_07855	COG3706	GGDEF domain
KFS84_07860	COG1509	lysine 2,3-aminomutase activity
KFS84_07870	COG3548	integral membrane protein
KFS84_07875	COG0402	S-adenosylhomocysteine deaminase activity
KFS84_07910	COG4677	pectinesterase activity
KFS84_07920	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
KFS84_07970	COG2166	iron-sulfur cluster assembly
KFS84_07985	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KFS84_07990	COG0137	argininosuccinate synthase activity
KFS84_07995	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KFS84_08000	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
KFS84_08010	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KFS84_08015	COG0165	Argininosuccinate lyase
KFS84_08035	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KFS84_08070	COG1294	oxidase, subunit
KFS84_08080	COG4988	ABC transporter
KFS84_08085	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KFS84_08115	COG1187	pseudouridine synthase activity
KFS84_08140	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KFS84_08165	COG1132	(ABC) transporter
KFS84_08235	COG1981	membrane
KFS84_08265	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KFS84_08275	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KFS84_08280	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KFS84_08285	COG0750	zinc metalloprotease
KFS84_08290	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
KFS84_08295	COG0575	Belongs to the CDS family
KFS84_08300	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KFS84_08310	COG0528	UMP kinase activity
KFS84_08320	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KFS84_08370	COG0024	Methionine aminopeptidase
KFS84_08385	COG1393	Belongs to the ArsC family
KFS84_08390	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KFS84_08400	COG0367	asparagine synthase
KFS84_08440	COG1566	PFAM secretion protein HlyD family protein
KFS84_08445	COG2814	Major facilitator Superfamily
KFS84_08480	COG0557	exoribonuclease II activity
KFS84_08490	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KFS84_08510	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KFS84_08530	COG0704	Plays a role in the regulation of phosphate uptake
KFS84_08540	COG0581	inorganic phosphate transmembrane transporter activity
KFS84_08545	COG0573	inorganic phosphate transmembrane transporter activity
KFS84_08550	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KFS84_08555	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KFS84_08575	COG0659	secondary active sulfate transmembrane transporter activity
KFS84_08625	COG1012	belongs to the aldehyde dehydrogenase family
KFS84_08640	COG4535	Mg2 and Co2 transporter CorC
KFS84_08655	COG1702	phosphate starvation-inducible protein PhoH
KFS84_08670	COG0741	lytic transglycosylase activity
KFS84_08675	COG0723	plastoquinol--plastocyanin reductase activity
KFS84_08680	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KFS84_08690	COG2857	Cytochrome c1
KFS84_08695	COG0625	glutathione transferase activity
KFS84_08700	COG2969	positive regulation of protein catabolic process
KFS84_08720	COG3844	kynureninase activity
KFS84_08735	COG0288	reversible hydration of carbon dioxide
KFS84_08785	COG2197	response regulator
KFS84_08810	COG0316	Belongs to the HesB IscA family
KFS84_08815	COG2977	Belongs to the P-Pant transferase superfamily
KFS84_08845	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KFS84_08850	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KFS84_08855	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
KFS84_08865	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
KFS84_08895	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KFS84_08915	COG1309	transcriptional regulator
KFS84_08935	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
KFS84_08955	COG1228	amidohydrolase
KFS84_09010	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KFS84_09015	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KFS84_09020	COG0077	Prephenate dehydratase
KFS84_09020	COG1605	Chorismate mutase
KFS84_09050	COG0583	DNA-binding transcription factor activity
KFS84_09075	COG1530	ribonuclease E activity
KFS84_09090	COG0428	transporter
KFS84_09105	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
KFS84_09105	COG0316	Belongs to the HesB IscA family
KFS84_09125	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KFS84_09145	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KFS84_09150	COG2957	Belongs to the agmatine deiminase family
KFS84_09160	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KFS84_09165	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
KFS84_09170	COG0539	negative regulation of cytoplasmic translation
KFS84_09175	COG0776	regulation of translation
KFS84_09185	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
KFS84_09190	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KFS84_09200	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KFS84_09205	COG0183	Belongs to the thiolase family
KFS84_09210	COG1024	Enoyl-CoA hydratase
KFS84_09210	COG1250	3-hydroxyacyl-CoA dehydrogenase
KFS84_09225	COG0820	rRNA (adenine-C2-)-methyltransferase activity
KFS84_09235	COG1426	Protein conserved in bacteria
KFS84_09245	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KFS84_09255	COG0746	molybdenum cofactor guanylyltransferase activity
KFS84_09265	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KFS84_09285	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KFS84_09300	COG1501	Belongs to the glycosyl hydrolase 31 family
KFS84_09305	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
KFS84_09315	COG1914	H( )-stimulated, divalent metal cation uptake system
KFS84_09320	COG1321	iron dependent repressor
KFS84_09330	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
KFS84_09335	COG0668	transmembrane transport
KFS84_09345	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
KFS84_09360	COG1028	Short-chain dehydrogenase reductase Sdr
KFS84_09365	COG1183	phosphatidylcholine synthase activity
KFS84_09375	COG3243	poly(R)-hydroxyalkanoic acid synthase
KFS84_09395	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KFS84_09395	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
KFS84_09405	COG0784	Response regulator, receiver
KFS84_09405	COG4191	Histidine kinase
KFS84_09410	COG2183	response to ionizing radiation
KFS84_09415	COG2205	protein histidine kinase activity
KFS84_09415	COG0784	Response regulator, receiver
KFS84_09505	COG1649	PFAM Uncharacterised BCR, COG1649
KFS84_09585	COG1132	(ABC) transporter
KFS84_09635	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
KFS84_09645	COG2801	Transposase and inactivated derivatives
KFS84_09660	COG0438	transferase activity, transferring glycosyl groups
KFS84_09665	COG0438	transferase activity, transferring glycosyl groups
KFS84_09705	COG2244	polysaccharide biosynthetic process
KFS84_09735	COG3038	cytochrome b561
KFS84_09755	COG1595	DNA-templated transcription, initiation
KFS84_09790	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KFS84_09825	COG0038	chloride channel
KFS84_09830	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KFS84_09850	COG1674	ftsk spoiiie
KFS84_09855	COG0492	ferredoxin-NADP+ reductase activity
KFS84_09865	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
KFS84_09875	COG0542	response to heat
KFS84_09895	COG0482	sulfurtransferase activity
KFS84_09900	COG2915	High frequency lysogenization protein hflD homolog
KFS84_09920	COG1116	anion transmembrane transporter activity
KFS84_09955	COG0835	chemotaxis
KFS84_09965	COG0840	transmembrane signaling receptor activity
KFS84_09975	COG0840	transmembrane signaling receptor activity
KFS84_10035	COG0318	PFAM AMP-dependent synthetase and ligase
KFS84_10040	COG1024	Enoyl-CoA hydratase
KFS84_10045	COG2205	protein histidine kinase activity
KFS84_10045	COG2198	Histidine kinase
KFS84_10045	COG0784	Response regulator, receiver
KFS84_10065	COG3279	Response regulator of the LytR AlgR family
KFS84_10070	COG4676	Protein conserved in bacteria
KFS84_10085	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KFS84_10090	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
KFS84_10100	COG0505	Belongs to the CarA family
KFS84_10140	COG1024	Enoyl-CoA hydratase
KFS84_10150	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KFS84_10170	COG1515	deoxyribonuclease V activity
KFS84_10200	COG5001	Diguanylate cyclase
KFS84_10235	COG1132	(ABC) transporter
KFS84_10250	COG1605	Chorismate mutase
KFS84_10250	COG0287	Prephenate dehydrogenase
KFS84_10270	COG0484	heat shock protein binding
KFS84_10275	COG0443	Heat shock 70 kDa protein
KFS84_10280	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KFS84_10285	COG1420	regulation of RNA biosynthetic process
KFS84_10290	COG0497	DNA recombination
KFS84_10295	COG0735	belongs to the Fur family
KFS84_10300	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KFS84_10310	COG2867	negative regulation of translational initiation
KFS84_10315	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
KFS84_10405	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KFS84_10425	COG0583	DNA-binding transcription factor activity
KFS84_10440	COG0415	Belongs to the DNA photolyase family
KFS84_10445	COG0305	Participates in initiation and elongation during chromosome replication
KFS84_10455	COG1960	acyl-CoA dehydrogenase activity
KFS84_10485	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KFS84_10595	COG0386	Belongs to the glutathione peroxidase family
KFS84_10605	COG1846	Transcriptional regulator
KFS84_10640	COG1472	Belongs to the glycosyl hydrolase 3 family
KFS84_10650	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KFS84_10680	COG0488	(ABC) transporter
KFS84_10685	COG0513	Belongs to the DEAD box helicase family
KFS84_10710	COG0657	acetylesterase activity
KFS84_10725	COG0564	pseudouridine synthase activity
KFS84_10730	COG4681	YaeQ
KFS84_10735	COG2081	HI0933 family
KFS84_10780	COG1028	Short-chain dehydrogenase reductase Sdr
KFS84_10805	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KFS84_10810	COG0860	N-Acetylmuramoyl-L-alanine amidase
KFS84_10815	COG0802	atpase or kinase
KFS84_10820	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KFS84_10820	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
KFS84_10870	COG1960	acyl-CoA dehydrogenase activity
KFS84_10880	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KFS84_10900	COG0438	transferase activity, transferring glycosyl groups
KFS84_10910	COG0438	transferase activity, transferring glycosyl groups
KFS84_10915	COG0438	transferase activity, transferring glycosyl groups
KFS84_10960	COG0072	phenylalanine-tRNA ligase activity
KFS84_10960	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KFS84_10965	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KFS84_10970	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KFS84_10980	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KFS84_11005	COG0556	nucleotide-excision repair
KFS84_11010	COG4966	pilus assembly protein PilW
KFS84_11065	COG3275	phosphorelay sensor kinase activity
KFS84_11070	COG1611	Belongs to the LOG family
KFS84_11080	COG2095	MarC family integral membrane protein
KFS84_11085	COG1028	Short-chain dehydrogenase reductase Sdr
KFS84_11090	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
KFS84_11130	COG2925	Exonuclease
KFS84_11170	COG2902	Dehydrogenase
KFS84_11180	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KFS84_11185	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KFS84_11190	COG1960	acyl-CoA dehydrogenase activity
KFS84_11195	COG2226	methyltransferase
KFS84_11200	COG0646	methionine synthase
KFS84_11200	COG1410	methionine synthase
KFS84_11205	COG1410	methionine synthase
KFS84_11205	COG0646	methionine synthase
KFS84_11225	COG2900	Belongs to the SlyX family
KFS84_11240	COG0386	Belongs to the glutathione peroxidase family
KFS84_11250	COG1725	Transcriptional regulator
KFS84_11255	COG1131	(ABC) transporter
KFS84_11300	COG2850	peptidyl-arginine hydroxylation
KFS84_11310	COG0567	Dehydrogenase, E1 component
KFS84_11345	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KFS84_11375	COG1024	Enoyl-CoA hydratase
KFS84_11395	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KFS84_11420	COG0277	FAD linked oxidase domain protein
KFS84_11425	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KFS84_11440	COG0531	amino acid
KFS84_11445	COG0531	amino acid
KFS84_11450	COG0235	Class ii aldolase
KFS84_11460	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
KFS84_11465	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
KFS84_11485	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KFS84_11485	COG0140	phosphoribosyl-ATP diphosphatase activity
KFS84_11500	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KFS84_11510	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KFS84_11515	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KFS84_11520	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
KFS84_11530	COG0124	histidyl-tRNA synthetase
KFS84_11535	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KFS84_11545	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KFS84_11555	COG2951	lytic endotransglycosylase activity
KFS84_11565	COG0527	aspartate kinase activity
KFS84_11565	COG0460	homoserine dehydrogenase
KFS84_11580	COG1012	belongs to the aldehyde dehydrogenase family
KFS84_11595	COG0167	dihydroorotate dehydrogenase activity
KFS84_11600	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KFS84_11625	COG0671	phosphoesterase, PA-phosphatase related
KFS84_11640	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
KFS84_11685	COG0166	Belongs to the GPI family
KFS84_11700	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
KFS84_11710	COG0617	tRNA 3'-terminal CCA addition
KFS84_11730	COG0860	N-Acetylmuramoyl-L-alanine amidase
KFS84_11740	COG0477	Major facilitator Superfamily
KFS84_11745	COG2115	Belongs to the xylose isomerase family
KFS84_11750	COG1070	Carbohydrate kinase
KFS84_11760	COG1501	Belongs to the glycosyl hydrolase 31 family
KFS84_11780	COG0800	Aldolase
KFS84_11795	COG3734	2-keto-3-deoxy-galactonokinase
KFS84_11800	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
KFS84_11810	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KFS84_11820	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KFS84_11825	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
KFS84_11840	COG0352	thiamine-phosphate diphosphorylase activity
KFS84_11840	COG0351	phosphomethylpyrimidine kinase
KFS84_11860	COG0583	DNA-binding transcription factor activity
KFS84_11865	COG1741	Belongs to the pirin family
KFS84_11890	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
KFS84_11900	COG2137	regulation of response to DNA damage stimulus
KFS84_11905	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KFS84_11910	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KFS84_11915	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
KFS84_11920	COG1546	Belongs to the CinA family
KFS84_11925	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KFS84_11940	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KFS84_11945	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KFS84_11950	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
KFS84_11955	COG1534	Rna-binding protein
KFS84_11970	COG1238	metal cluster binding
KFS84_11980	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
KFS84_11995	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
KFS84_12000	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
KFS84_12005	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
KFS84_12015	COG2877	3-deoxy-8-phosphooctulonate synthase activity
KFS84_12055	COG1253	flavin adenine dinucleotide binding
KFS84_12070	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KFS84_12110	COG0069	glutamate synthase activity
KFS84_12115	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
KFS84_12125	COG1609	Transcriptional regulator
KFS84_12130	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
KFS84_12130	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KFS84_12135	COG1105	Belongs to the carbohydrate kinase PfkB family
KFS84_12140	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KFS84_12140	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KFS84_12170	COG0577	efflux transmembrane transporter activity
KFS84_12170	COG1136	(ABC) transporter
KFS84_12220	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KFS84_12230	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KFS84_12235	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
KFS84_12245	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KFS84_12255	COG0348	domain, Protein
KFS84_12290	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KFS84_12305	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KFS84_12315	COG1663	tetraacyldisaccharide 4'-kinase activity
KFS84_12320	COG1132	(ABC) transporter
KFS84_12325	COG0848	biopolymer transport protein
KFS84_12330	COG0811	peptide transport
KFS84_12370	COG4591	ABC-type transport system involved in lipoprotein release permease component
KFS84_12380	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
KFS84_12395	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
KFS84_12400	COG2009	succinate dehydrogenase
KFS84_12410	COG0354	folic acid binding
KFS84_12415	COG3842	ATPase activity
KFS84_12420	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KFS84_12435	COG0129	dihydroxy-acid dehydratase activity
KFS84_12440	COG0800	Aldolase
KFS84_12455	COG0395	ABC-type sugar transport system, permease component
KFS84_12490	COG2350	Protein conserved in bacteria
KFS84_12495	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KFS84_12500	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KFS84_12505	COG1187	pseudouridine synthase activity
KFS84_12540	COG0436	Aminotransferase
KFS84_12545	COG4133	protoheme IX ABC transporter activity
KFS84_12595	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KFS84_12710	COG0735	belongs to the Fur family
KFS84_12740	COG4452	Inner membrane protein CreD
KFS84_12770	COG0745	RESPONSE REGULATOR receiver
KFS84_12775	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
KFS84_12795	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KFS84_12805	COG2198	Histidine kinase
KFS84_12805	COG0643	Histidine kinase
KFS84_12810	COG0840	transmembrane signaling receptor activity
KFS84_12815	COG0840	transmembrane signaling receptor activity
KFS84_12820	COG0840	transmembrane signaling receptor activity
KFS84_12825	COG0835	chemotaxis
KFS84_12830	COG5001	Diguanylate cyclase
KFS84_12830	COG4251	negative regulation of phosphorylation
KFS84_12830	COG3706	GGDEF domain
KFS84_12830	COG2203	Gaf domain
KFS84_12860	COG2211	Major facilitator Superfamily
KFS84_12880	COG1515	deoxyribonuclease V activity
KFS84_12900	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KFS84_12925	COG1297	OPT oligopeptide transporter protein
KFS84_12950	COG3550	peptidyl-serine autophosphorylation
KFS84_12955	COG0629	single-stranded DNA binding
KFS84_12960	COG0142	geranyltranstransferase activity
KFS84_12985	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KFS84_13000	COG0527	aspartate kinase activity
KFS84_13005	COG0384	phenazine biosynthesis protein PhzF
KFS84_13015	COG1764	response to oxidative stress
KFS84_13030	COG0739	heme binding
KFS84_13050	COG0693	protein deglycase activity
KFS84_13065	COG0719	Fe-S assembly protein
KFS84_13070	COG0396	ATPase activity
KFS84_13075	COG0719	Fe-S assembly protein
KFS84_13080	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KFS84_13090	COG2146	nitrite reductase [NAD(P)H] activity
KFS84_13095	COG4774	siderophore transport
KFS84_13120	COG1477	protein flavinylation
KFS84_13125	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KFS84_13145	COG1555	photosystem II stabilization
KFS84_13160	COG3178	'Phosphotransferase
KFS84_13165	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KFS84_13175	COG0628	permease
KFS84_13195	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KFS84_13245	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
KFS84_13260	COG1137	ATPase activity
KFS84_13275	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KFS84_13285	COG1660	Displays ATPase and GTPase activities
KFS84_13295	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KFS84_13300	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KFS84_13305	COG2239	Acts as a magnesium transporter
KFS84_13355	COG2801	Transposase and inactivated derivatives
KFS84_13385	COG3590	peptidase
KFS84_13440	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KFS84_13445	COG2311	Membrane
KFS84_13450	COG1047	Peptidyl-prolyl cis-trans
KFS84_13455	COG0791	NLP P60 protein
KFS84_13460	COG0791	NLP P60 protein
KFS84_13465	COG1607	acyl-coa hydrolase
KFS84_13475	COG1301	dicarboxylic acid transport
KFS84_13480	COG1785	Belongs to the alkaline phosphatase family
KFS84_13495	COG1722	exodeoxyribonuclease VII activity
KFS84_13500	COG0142	geranyltranstransferase activity
KFS84_13510	COG4104	PAAR repeat-containing protein
KFS84_13530	COG0312	modulator of DNA gyrase
KFS84_13540	COG0312	modulator of DNA gyrase
KFS84_13560	COG2968	Membrane
KFS84_13595	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KFS84_13610	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KFS84_13625	COG0495	leucyl-tRNA aminoacylation
KFS84_13635	COG3118	belongs to the thioredoxin family
KFS84_13650	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
KFS84_13660	COG2040	homocysteine
KFS84_13665	COG0833	amino acid
KFS84_13675	COG0346	lactoylglutathione lyase activity
KFS84_13705	COG2878	Part of a membrane complex involved in electron transport
KFS84_13720	COG1595	DNA-templated transcription, initiation
KFS84_13745	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KFS84_13765	COG0251	oxidation-reduction process
KFS84_13775	COG0392	lysyltransferase activity
KFS84_13775	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KFS84_13805	COG2814	Major facilitator Superfamily
KFS84_13810	COG1902	pentaerythritol trinitrate reductase activity
KFS84_13815	COG2824	Alkylphosphonate utilization operon protein PhnA
KFS84_13820	COG1047	Peptidyl-prolyl cis-trans
KFS84_13825	COG1077	Cell shape determining protein MreB Mrl
KFS84_13860	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KFS84_13870	COG1451	nucleotide metabolic process
KFS84_13890	COG2205	protein histidine kinase activity
KFS84_13890	COG2198	Histidine kinase
KFS84_13890	COG0784	Response regulator, receiver
KFS84_13900	COG2186	Transcriptional regulator
KFS84_13905	COG3250	beta-galactosidase activity
KFS84_13955	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
KFS84_13955	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
KFS84_13955	COG1703	isobutyryl-CoA mutase activity
KFS84_13980	COG0183	Belongs to the thiolase family
KFS84_14020	COG1793	dna ligase
KFS84_14020	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
KFS84_14025	COG1793	dna ligase
KFS84_14025	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
KFS84_14030	COG1201	RNA secondary structure unwinding
KFS84_14040	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KFS84_14045	COG1278	Cold shock
KFS84_14050	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
KFS84_14055	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
KFS84_14060	COG1472	Belongs to the glycosyl hydrolase 3 family
KFS84_14065	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KFS84_14070	COG2954	triphosphatase activity
KFS84_14080	COG2204	response regulator
KFS84_14085	COG1381	Involved in DNA repair and RecF pathway recombination
KFS84_14090	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KFS84_14105	COG0681	Belongs to the peptidase S26 family
KFS84_14110	COG0481	GTPase activity
KFS84_14115	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KFS84_14130	COG1024	Enoyl-CoA hydratase
KFS84_14130	COG1250	3-hydroxyacyl-CoA dehydrogenase
KFS84_14155	COG2855	membrane
KFS84_14170	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KFS84_14200	COG0534	Mate efflux family protein
KFS84_14205	COG0335	large ribosomal subunit rRNA binding
KFS84_14215	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KFS84_14220	COG0228	four-way junction DNA binding
KFS84_14230	COG2070	2-Nitropropane dioxygenase
KFS84_14235	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KFS84_14270	COG0475	glutathione-regulated potassium exporter activity
KFS84_14285	COG0625	glutathione transferase activity
KFS84_14290	COG1082	Xylose isomerase domain protein TIM barrel
KFS84_14300	COG1172	Belongs to the binding-protein-dependent transport system permease family
KFS84_14305	COG1172	Belongs to the binding-protein-dependent transport system permease family
KFS84_14310	COG1129	ABC transporter
KFS84_14315	COG1879	ABC-type sugar transport system periplasmic component
KFS84_14320	COG1012	belongs to the aldehyde dehydrogenase family
KFS84_14340	COG0129	dihydroxy-acid dehydratase activity
KFS84_14365	COG2207	Transcriptional regulator
KFS84_14390	COG1317	bacterial-type flagellum organization
KFS84_14415	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KFS84_14440	COG4794	Type iii secretion
KFS84_14475	COG0745	RESPONSE REGULATOR receiver
KFS84_14540	COG3152	Membrane
KFS84_14550	COG0156	8-amino-7-oxononanoate synthase activity
KFS84_14570	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
KFS84_14575	COG1845	cytochrome c oxidase, subunit III
KFS84_14580	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KFS84_14605	COG1132	(ABC) transporter
KFS84_14640	COG5001	Diguanylate cyclase
KFS84_14665	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
KFS84_14680	COG0196	riboflavin kinase activity
KFS84_14685	COG0728	peptidoglycan biosynthetic process
KFS84_14695	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KFS84_14700	COG0211	Belongs to the bacterial ribosomal protein bL27 family
KFS84_14705	COG0261	This protein binds to 23S rRNA in the presence of protein L20
KFS84_14710	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KFS84_14715	COG0824	Thioesterase
KFS84_14725	COG1024	Enoyl-CoA hydratase
KFS84_14730	COG1946	Acyl-CoA thioesterase
KFS84_14745	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
KFS84_14810	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KFS84_14855	COG1643	Atp-dependent helicase
KFS84_14860	COG0783	Belongs to the Dps family
KFS84_14870	COG0514	ATP-dependent DNA helicase (RecQ)
KFS84_14890	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KFS84_14895	COG0602	queuosine metabolic process
KFS84_14900	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
KFS84_14905	COG2885	chlorophyll binding
KFS84_14920	COG0848	biopolymer transport protein
KFS84_14930	COG0824	Thioesterase
KFS84_14935	COG2255	four-way junction helicase activity
KFS84_14940	COG3158	transport of potassium into the cell
KFS84_14945	COG0632	four-way junction helicase activity
KFS84_14955	COG0217	transcriptional regulatory protein
KFS84_15015	COG0657	acetylesterase activity
KFS84_15015	COG2755	lipolytic protein G-D-S-L family
KFS84_15040	COG0488	(ABC) transporter
KFS84_15085	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KFS84_15085	COG4651	solute:proton antiporter activity
KFS84_15095	COG4772	TonB-dependent receptor
KFS84_15105	COG4264	IucA IucC family
KFS84_15110	COG2814	Major facilitator Superfamily
KFS84_15115	COG4264	IucA IucC family
KFS84_15120	COG0019	diaminopimelate decarboxylase activity
KFS84_15145	COG0542	response to heat
KFS84_15170	COG0454	-acetyltransferase
KFS84_15190	COG1877	trehalose-phosphatase activity
KFS84_15195	COG3387	PFAM Glycoside hydrolase 15-related
KFS84_15210	COG4993	Dehydrogenase
KFS84_15220	COG0840	transmembrane signaling receptor activity
KFS84_15230	COG0564	pseudouridine synthase activity
KFS84_15235	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KFS84_15245	COG1125	glycine betaine transport
KFS84_15250	COG1174	glycine betaine transport
KFS84_15265	COG1262	PFAM Formylglycine-generating sulfatase enzyme
KFS84_15280	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
KFS84_15280	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KFS84_15290	COG4993	Dehydrogenase
KFS84_15315	COG3657	addiction module killer protein
KFS84_15320	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KFS84_15365	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
KFS84_15380	COG0745	RESPONSE REGULATOR receiver
KFS84_15390	COG0189	ligase activity
KFS84_15445	COG2022	thiamine diphosphate biosynthetic process
KFS84_15455	COG0471	metal ion transport
KFS84_15455	COG3273	potassium ion transport
KFS84_15470	COG0179	Fumarylacetoacetate (FAA) hydrolase
KFS84_15485	COG1609	Transcriptional regulator
KFS84_15500	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KFS84_15510	COG1115	amino acid carrier protein
KFS84_15530	COG0438	transferase activity, transferring glycosyl groups
KFS84_15540	COG0840	transmembrane signaling receptor activity
KFS84_15545	COG0529	Catalyzes the synthesis of activated sulfate
KFS84_15545	COG2895	sulfate adenylyltransferase (ATP) activity
KFS84_15555	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KFS84_15560	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KFS84_15565	COG0175	sulfate reduction
KFS84_15595	COG1393	Belongs to the ArsC family
KFS84_15600	COG2198	Histidine kinase
KFS84_15600	COG0784	Response regulator, receiver
KFS84_15600	COG2205	protein histidine kinase activity
KFS84_15620	COG1648	precorrin-2 dehydrogenase activity
KFS84_15620	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KFS84_15655	COG1529	Aldehyde oxidase and xanthine dehydrogenase
KFS84_15665	COG2351	hydroxyisourate hydrolase activity
KFS84_15670	COG2072	flavoprotein involved in K transport
KFS84_15690	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KFS84_15735	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
KFS84_15745	COG3588	fructose-bisphosphate aldolase
KFS84_15750	COG0469	pyruvate kinase activity
KFS84_15795	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KFS84_15800	COG3047	cAMP biosynthetic process
KFS84_15820	COG0640	Transcriptional regulator
KFS84_15830	COG0725	ABC transporter, periplasmic molybdate-binding protein
KFS84_15835	COG4149	molybdate abc transporter
KFS84_15840	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
KFS84_15880	COG1376	ErfK ybiS ycfS ynhG family protein
KFS84_15885	COG0739	heme binding
KFS84_15915	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KFS84_15950	COG0714	Associated with various cellular activities
KFS84_15980	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
KFS84_16005	COG0372	Belongs to the citrate synthase family
KFS84_16010	COG0254	rRNA binding
KFS84_16025	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KFS84_16050	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KFS84_16055	COG1758	RNA polymerase activity
KFS84_16060	COG0194	GDP metabolic process
KFS84_16065	COG1561	YicC-like family, N-terminal region
KFS84_16070	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
KFS84_16075	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KFS84_16080	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KFS84_16105	COG1289	transmembrane transporter activity
KFS84_16110	COG2814	Major facilitator Superfamily
KFS84_16130	COG0006	proline dipeptidase activity
KFS84_16135	COG3079	Belongs to the UPF0149 family
KFS84_16160	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KFS84_16170	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KFS84_16185	COG1773	rubredoxin
KFS84_16200	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
KFS84_16220	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KFS84_16225	COG1295	ribonuclease BN
KFS84_16245	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KFS84_16250	COG1404	Belongs to the peptidase S8 family
KFS84_16255	COG1404	Belongs to the peptidase S8 family
KFS84_16260	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KFS84_16330	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KFS84_16330	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KFS84_16375	COG3634	alkyl hydroperoxide reductase activity
KFS84_16380	COG0583	DNA-binding transcription factor activity
KFS84_16390	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KFS84_16410	COG2197	response regulator
KFS84_16435	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KFS84_16440	COG0697	spore germination
KFS84_16500	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KFS84_16505	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KFS84_16515	COG2096	Adenosyltransferase
KFS84_16525	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
KFS84_16530	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KFS84_16535	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
KFS84_16545	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KFS84_16550	COG2967	ApaG domain
KFS84_16555	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KFS84_16590	COG1704	LemA family
KFS84_16595	COG0861	Integral membrane protein TerC family
KFS84_16600	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KFS84_16610	COG0642	Histidine kinase
KFS84_16625	COG4181	ATPase activity
KFS84_16630	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
KFS84_16660	COG0667	Aldo Keto reductase
KFS84_16665	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KFS84_16685	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KFS84_16705	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KFS84_16780	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KFS84_16795	COG0494	nUDIX hydrolase
KFS84_16810	COG0739	heme binding
KFS84_16820	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
KFS84_16825	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KFS84_16835	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KFS84_16840	COG1181	Belongs to the D-alanine--D-alanine ligase family
KFS84_16865	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KFS84_16880	COG3116	cell division
KFS84_16885	COG0275	rRNA processing
KFS84_16890	COG2001	Belongs to the MraZ family
KFS84_16925	COG0277	FAD linked oxidase domain protein
KFS84_16935	COG0745	RESPONSE REGULATOR receiver
KFS84_16940	COG2205	protein histidine kinase activity
KFS84_16950	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
KFS84_16955	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
KFS84_16980	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
KFS84_16985	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KFS84_16990	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
KFS84_17005	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KFS84_17005	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KFS84_17015	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KFS84_17040	COG0488	(ABC) transporter
KFS84_17045	COG0242	peptide deformylase activity
KFS84_17055	COG1960	acyl-CoA dehydrogenase activity
KFS84_17065	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KFS84_17095	COG1215	transferase activity, transferring glycosyl groups
KFS84_17105	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KFS84_17185	COG2188	Transcriptional regulator
KFS84_17205	COG1450	Type ii and iii secretion system protein
KFS84_17220	COG3166	PFAM Fimbrial assembly family protein
KFS84_17225	COG3156	type II secretion system protein K
KFS84_17230	COG4795	General secretion pathway protein
KFS84_17235	COG2165	general secretion pathway protein
KFS84_17240	COG4970	Tfp pilus assembly protein FimT
KFS84_17245	COG2165	general secretion pathway protein
KFS84_17250	COG1459	type II secretion system
KFS84_17255	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KFS84_17260	COG1404	Belongs to the peptidase S8 family
KFS84_17265	COG5295	Hep Hag repeat protein
KFS84_17280	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KFS84_17280	COG0047	phosphoribosylformylglycinamidine synthase activity
KFS84_17285	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KFS84_17290	COG4974	Belongs to the 'phage' integrase family
KFS84_17315	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KFS84_17325	COG0525	valine-tRNA ligase activity
KFS84_17355	COG1183	phosphatidylcholine synthase activity
KFS84_17365	COG0442	prolyl-tRNA aminoacylation
KFS84_17380	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
KFS84_17385	COG1127	ABC transporter
KFS84_17390	COG3218	ABC-type transport auxiliary lipoprotein component
KFS84_17390	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
KFS84_17420	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KFS84_17425	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KFS84_17430	COG0662	Cupin 2, conserved barrel domain protein
KFS84_17430	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
KFS84_17455	COG2086	electron transfer activity
KFS84_17475	COG0277	FAD linked oxidase domain protein
KFS84_17480	COG0300	oxidoreductase activity
KFS84_17485	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KFS84_17505	COG0493	'glutamate synthase
KFS84_17555	COG1216	Glycosyl transferase, family 2
KFS84_17555	COG0438	transferase activity, transferring glycosyl groups
KFS84_17560	COG0438	transferase activity, transferring glycosyl groups
KFS84_17560	COG1216	Glycosyl transferase, family 2
KFS84_17580	COG0626	cystathionine gamma-synthase activity
KFS84_17640	COG0596	Alpha beta hydrolase
KFS84_17640	COG0508	dehydrogenase complex catalyzes the overall conversion of
KFS84_17645	COG0308	aminopeptidase N
KFS84_17650	COG2226	methyltransferase
KFS84_17715	COG2832	Protein of unknown function (DUF454)
KFS84_17730	COG0436	Aminotransferase
KFS84_17735	COG1505	serine-type exopeptidase activity
KFS84_17750	COG1733	regulation of RNA biosynthetic process
KFS84_17800	COG0181	hydroxymethylbilane synthase activity
KFS84_17845	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KFS84_17880	COG0243	molybdopterin cofactor binding
KFS84_17885	COG2146	nitrite reductase [NAD(P)H] activity
KFS84_17890	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KFS84_17895	COG2223	nitrite transmembrane transporter activity
KFS84_17900	COG1116	anion transmembrane transporter activity
KFS84_17900	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KFS84_17910	COG1648	precorrin-2 dehydrogenase activity
KFS84_17910	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KFS84_17930	COG2204	response regulator
KFS84_17935	COG4191	Histidine kinase
KFS84_17940	COG0028	Belongs to the TPP enzyme family
KFS84_17955	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KFS84_17970	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
KFS84_17980	COG1028	Short-chain dehydrogenase reductase Sdr
KFS84_17985	COG0840	transmembrane signaling receptor activity
KFS84_18025	COG1309	transcriptional regulator
KFS84_18085	COG1487	ribonuclease activity
KFS84_18115	COG0366	Alpha amylase catalytic
KFS84_18120	COG0366	Alpha amylase catalytic
KFS84_18130	COG1609	Transcriptional regulator
KFS84_18145	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KFS84_18150	COG1490	D-aminoacyl-tRNA deacylase activity
KFS84_18165	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KFS84_18185	COG1215	transferase activity, transferring glycosyl groups
KFS84_18200	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KFS84_18205	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KFS84_18205	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KFS84_18210	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KFS84_18215	COG0242	peptide deformylase activity
KFS84_18220	COG1652	LysM domain
KFS84_18225	COG0758	DNA mediated transformation
KFS84_18240	COG1714	RDD family
KFS84_18245	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KFS84_18245	COG1754	DNA topoisomerase type I activity
KFS84_18250	COG0009	L-threonylcarbamoyladenylate synthase
KFS84_18275	COG4771	TonB-dependent receptor
KFS84_18295	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KFS84_18335	COG1999	signal sequence binding
KFS84_18355	COG4774	siderophore transport
KFS84_18400	COG1280	lysine exporter protein (LysE YggA)
KFS84_18455	COG1012	belongs to the aldehyde dehydrogenase family
KFS84_18510	COG0530	calcium, potassium:sodium antiporter activity
KFS84_18525	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
KFS84_18545	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
KFS84_18550	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
KFS84_18595	COG3135	benzoate transporter
KFS84_18620	COG2951	lytic endotransglycosylase activity
KFS84_18640	COG0730	response to heat
KFS84_18665	COG0302	gtp cyclohydrolase
KFS84_18670	COG0477	Major facilitator Superfamily
KFS84_18760	COG0537	adenosine 5'-monophosphoramidase activity
KFS84_18780	COG1074	ATP-dependent DNA helicase activity
KFS84_18785	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
KFS84_18790	COG1127	ABC transporter
KFS84_18795	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
KFS84_18800	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
KFS84_18815	COG2853	Lipoprotein
KFS84_18825	COG0546	phosphoglycolate phosphatase activity
KFS84_18850	COG0339	signal peptide processing
KFS84_18855	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KFS84_18865	COG2217	Heavy metal translocating P-type atpase
KFS84_18880	COG2132	Multicopper oxidase
KFS84_18905	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KFS84_18920	COG1136	(ABC) transporter
KFS84_18930	COG0577	efflux transmembrane transporter activity
KFS84_18940	COG1136	(ABC) transporter
KFS84_18940	COG0577	efflux transmembrane transporter activity
KFS84_18995	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KFS84_19010	COG0355	proton-transporting ATP synthase activity, rotational mechanism
KFS84_19025	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KFS84_19035	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KFS84_19045	COG0356	it plays a direct role in the translocation of protons across the membrane
KFS84_19060	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KFS84_19065	COG0508	dehydrogenase complex catalyzes the overall conversion of
KFS84_19100	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KFS84_19105	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KFS84_19150	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KFS84_19165	COG4807	Protein conserved in bacteria
KFS84_19175	COG1418	mRNA catabolic process
KFS84_19190	COG4773	Receptor
KFS84_19205	COG0412	Dienelactone hydrolase
KFS84_19265	COG0284	orotidine-5'-phosphate decarboxylase activity
KFS84_19295	COG1609	Transcriptional regulator
KFS84_19305	COG2937	Belongs to the GPAT DAPAT family
KFS84_19330	COG2211	Major facilitator Superfamily
KFS84_19345	COG3693	PFAM glycoside hydrolase, family 10
KFS84_19365	COG3386	PFAM SMP-30 Gluconolaconase
KFS84_19445	COG0583	DNA-binding transcription factor activity
KFS84_19465	COG0697	spore germination
KFS84_19475	COG1113	amino acid transport
KFS84_19480	COG0598	Magnesium transport protein CorA
KFS84_19490	COG2207	Transcriptional regulator
KFS84_19495	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
KFS84_19540	COG1472	Belongs to the glycosyl hydrolase 3 family
KFS84_19550	COG4948	Mandelate Racemase Muconate Lactonizing
KFS84_19560	COG3661	Belongs to the glycosyl hydrolase 67 family
KFS84_19570	COG2115	Belongs to the xylose isomerase family
KFS84_19575	COG0037	tRNA processing
KFS84_19605	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KFS84_19615	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KFS84_19625	COG0805	protein transport
KFS84_19635	COG0519	Catalyzes the synthesis of GMP from XMP
KFS84_19635	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KFS84_19640	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KFS84_19720	COG0270	DNA (cytosine-5-)-methyltransferase activity
KFS84_19730	COG0840	transmembrane signaling receptor activity
KFS84_19765	COG2353	YceI-like domain
KFS84_19810	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
KFS84_19835	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KFS84_19840	COG0459	protein refolding
KFS84_19855	COG1324	tolerance protein
KFS84_19865	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KFS84_19880	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
KFS84_19885	COG0511	ligase activity, forming carbon-carbon bonds
KFS84_19890	COG0439	Biotin carboxylase
KFS84_19910	COG0564	pseudouridine synthase activity
KFS84_19940	COG1181	Belongs to the D-alanine--D-alanine ligase family
KFS84_19950	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KFS84_19965	COG0318	PFAM AMP-dependent synthetase and ligase
KFS84_19970	COG0727	PFAM Uncharacterised protein family (UPF0153)
KFS84_19980	COG0596	Alpha beta hydrolase
KFS84_19990	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KFS84_20000	COG0612	Peptidase, M16
KFS84_20010	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KFS84_20020	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
KFS84_20025	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
KFS84_20065	COG0183	Belongs to the thiolase family
KFS84_20080	COG2032	superoxide dismutase activity
KFS84_20085	COG2032	superoxide dismutase activity
KFS84_20090	COG2204	response regulator
KFS84_20095	COG3852	Histidine kinase
KFS84_20100	COG0004	ammonium transporteR
KFS84_20105	COG0347	Belongs to the P(II) protein family
KFS84_20110	COG0174	glutamine synthetase
KFS84_20115	COG1968	undecaprenyl-diphosphatase activity
KFS84_20135	COG2267	carboxylic ester hydrolase activity
KFS84_20145	COG2050	protein possibly involved in aromatic compounds catabolism
KFS84_20150	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KFS84_20160	COG2062	phosphohistidine phosphatase, SixA
KFS84_20165	COG1192	Involved in chromosome partitioning
KFS84_20215	COG2271	Major facilitator Superfamily
KFS84_20260	COG1111	helicase
KFS84_20260	COG1205	dead DEAH box helicase
KFS84_20320	COG0067	glutamate synthase
KFS84_20320	COG0069	glutamate synthase activity
KFS84_20320	COG0070	glutamate synthase
KFS84_20325	COG0493	'glutamate synthase
KFS84_20340	COG3104	oligopeptide transport
KFS84_20355	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KFS84_20410	COG0513	Belongs to the DEAD box helicase family
KFS84_20435	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KFS84_20445	COG2354	Protein conserved in bacteria
KFS84_20470	COG3264	Mechanosensitive ion channel
KFS84_20470	COG1196	nuclear chromosome segregation
KFS84_20475	COG0604	alcohol dehydrogenase
KFS84_20475	COG3321	synthase
KFS84_20475	COG1028	Short-chain dehydrogenase reductase Sdr
KFS84_20510	COG1011	Hydrolase
KFS84_20545	COG0577	efflux transmembrane transporter activity
KFS84_20550	COG1136	(ABC) transporter
KFS84_20560	COG1131	(ABC) transporter
KFS84_20580	COG2197	response regulator
KFS84_20590	COG0753	catalase activity
KFS84_20600	COG1304	FMN binding
KFS84_20605	COG2186	Transcriptional regulator
KFS84_20640	COG0210	DNA helicase
KFS84_20645	COG1435	thymidine kinase activity
KFS84_20660	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
KFS84_20670	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
KFS84_20700	COG0706	membrane insertase activity
KFS84_20705	COG0594	ribonuclease P activity