locus-tag	class	description
KFS86_00010	COG0592	DNA-directed DNA polymerase activity
KFS86_00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KFS86_00020	COG0187	DNA topoisomerase II activity
KFS86_00025	COG1266	CAAX protease self-immunity
KFS86_00030	COG0501	Belongs to the peptidase M48B family
KFS86_00060	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
KFS86_00070	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KFS86_00085	COG1280	lysine exporter protein (LysE YggA)
KFS86_00100	COG4772	TonB-dependent receptor
KFS86_00110	COG3284	Transcriptional regulator
KFS86_00115	COG1012	belongs to the aldehyde dehydrogenase family
KFS86_00155	COG1304	FMN binding
KFS86_00160	COG2186	Transcriptional regulator
KFS86_00180	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KFS86_00240	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KFS86_00260	COG4771	TonB-dependent receptor
KFS86_00305	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
KFS86_00320	COG3507	Belongs to the glycosyl hydrolase 43 family
KFS86_00325	COG1609	Transcriptional regulator
KFS86_00335	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
KFS86_00340	COG1028	Short-chain dehydrogenase reductase Sdr
KFS86_00355	COG3186	Phenylalanine-4-hydroxylase
KFS86_00360	COG1522	sequence-specific DNA binding
KFS86_00395	COG1752	Esterase of the alpha-beta hydrolase superfamily
KFS86_00410	COG0671	phosphoesterase, PA-phosphatase related
KFS86_00425	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KFS86_00460	COG1929	Belongs to the glycerate kinase type-1 family
KFS86_00470	COG0531	amino acid
KFS86_00475	COG4566	intracellular signal transduction
KFS86_00480	COG4191	Histidine kinase
KFS86_00500	COG1322	Protein conserved in bacteria
KFS86_00505	COG0386	Belongs to the glutathione peroxidase family
KFS86_00510	COG2853	Lipoprotein
KFS86_00525	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
KFS86_00530	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
KFS86_00535	COG1127	ABC transporter
KFS86_00540	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
KFS86_00545	COG1074	ATP-dependent DNA helicase activity
KFS86_00550	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KFS86_00570	COG0537	adenosine 5'-monophosphoramidase activity
KFS86_00575	COG1074	ATP-dependent DNA helicase activity
KFS86_00585	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KFS86_00635	COG0477	Major facilitator Superfamily
KFS86_00640	COG0302	gtp cyclohydrolase
KFS86_00665	COG0730	response to heat
KFS86_00680	COG2951	lytic endotransglycosylase activity
KFS86_00740	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
KFS86_00745	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
KFS86_00750	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
KFS86_00755	COG0493	'glutamate synthase
KFS86_00760	COG0067	glutamate synthase
KFS86_00760	COG0069	glutamate synthase activity
KFS86_00760	COG0070	glutamate synthase
KFS86_00805	COG1111	helicase
KFS86_00805	COG1205	dead DEAH box helicase
KFS86_00835	COG2271	Major facilitator Superfamily
KFS86_00880	COG2062	phosphohistidine phosphatase, SixA
KFS86_00890	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KFS86_00895	COG2050	protein possibly involved in aromatic compounds catabolism
KFS86_00905	COG2267	carboxylic ester hydrolase activity
KFS86_00915	COG1881	PFAM PEBP family protein
KFS86_00920	COG1968	undecaprenyl-diphosphatase activity
KFS86_00925	COG0174	glutamine synthetase
KFS86_00930	COG0347	Belongs to the P(II) protein family
KFS86_00935	COG0004	ammonium transporteR
KFS86_00940	COG3852	Histidine kinase
KFS86_00945	COG2204	response regulator
KFS86_00950	COG2032	superoxide dismutase activity
KFS86_00955	COG2032	superoxide dismutase activity
KFS86_00965	COG0183	Belongs to the thiolase family
KFS86_01005	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
KFS86_01010	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
KFS86_01020	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KFS86_01030	COG0612	Peptidase, M16
KFS86_01040	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KFS86_01045	COG3177	Filamentation induced by cAMP protein fic
KFS86_01060	COG0596	Alpha beta hydrolase
KFS86_01070	COG0727	PFAM Uncharacterised protein family (UPF0153)
KFS86_01075	COG0318	PFAM AMP-dependent synthetase and ligase
KFS86_01090	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KFS86_01100	COG1181	Belongs to the D-alanine--D-alanine ligase family
KFS86_01115	COG4232	protein-disulfide reductase activity
KFS86_01120	COG0564	pseudouridine synthase activity
KFS86_01140	COG0339	signal peptide processing
KFS86_01160	COG0583	DNA-binding transcription factor activity
KFS86_01165	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
KFS86_01170	COG2224	Isocitrate lyase
KFS86_01205	COG0659	secondary active sulfate transmembrane transporter activity
KFS86_01235	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KFS86_01240	COG2130	NADP-dependent
KFS86_01255	COG1187	pseudouridine synthase activity
KFS86_01260	COG3547	Transposase (IS116 IS110 IS902 family)
KFS86_01270	COG1643	Atp-dependent helicase
KFS86_01275	COG0084	hydrolase, TatD family'
KFS86_01315	COG0842	Transport permease protein
KFS86_01320	COG1131	(ABC) transporter
KFS86_01325	COG0633	Ferredoxin
KFS86_01325	COG0543	2 iron, 2 sulfur cluster binding
KFS86_01335	COG1476	TRANSCRIPTIONal
KFS86_01345	COG4555	ABC transporter
KFS86_01365	COG0625	glutathione transferase activity
KFS86_01410	COG0530	calcium, potassium:sodium antiporter activity
KFS86_01415	COG1320	monovalent cation:proton antiporter activity
KFS86_01420	COG2212	antiporter activity
KFS86_01425	COG1863	multisubunit Na H antiporter MnhE subunit
KFS86_01430	COG0651	ATP synthesis coupled electron transport
KFS86_01435	COG1006	Multisubunit Na H antiporter MnhC subunit
KFS86_01440	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KFS86_01440	COG2111	Na H antiporter
KFS86_01445	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KFS86_01460	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
KFS86_01475	COG1597	lipid kinase activity
KFS86_01505	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KFS86_01510	COG0134	indole-3-glycerol-phosphate synthase activity
KFS86_01520	COG0730	response to heat
KFS86_01525	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KFS86_01530	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KFS86_01545	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
KFS86_01570	COG1051	belongs to the nudix hydrolase family
KFS86_01575	COG2906	2 iron, 2 sulfur cluster binding
KFS86_01620	COG2816	NAD+ diphosphatase activity
KFS86_01660	COG2814	Major facilitator Superfamily
KFS86_01665	COG1289	transmembrane transporter activity
KFS86_01670	COG0151	Belongs to the GarS family
KFS86_01675	COG0138	bifunctional purine biosynthesis protein purh
KFS86_01680	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KFS86_01685	COG2267	carboxylic ester hydrolase activity
KFS86_01705	COG4589	Belongs to the CDS family
KFS86_01715	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
KFS86_01735	COG2264	protein methyltransferase activity
KFS86_01750	COG0439	Biotin carboxylase
KFS86_01755	COG0511	ligase activity, forming carbon-carbon bonds
KFS86_01760	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
KFS86_01770	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KFS86_01780	COG1324	tolerance protein
KFS86_01790	COG0459	protein refolding
KFS86_01795	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KFS86_01820	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
KFS86_01840	COG0584	glycerophosphoryl diester phosphodiesterase
KFS86_01865	COG2353	YceI-like domain
KFS86_01890	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KFS86_01970	COG2267	carboxylic ester hydrolase activity
KFS86_01995	COG0697	spore germination
KFS86_02000	COG1113	amino acid transport
KFS86_02005	COG0598	Magnesium transport protein CorA
KFS86_02015	COG2207	Transcriptional regulator
KFS86_02030	COG0741	lytic transglycosylase activity
KFS86_02045	COG5297	Belongs to the glycosyl hydrolase family 6
KFS86_02045	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
KFS86_02055	COG0531	amino acid
KFS86_02075	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
KFS86_02080	COG3275	phosphorelay sensor kinase activity
KFS86_02115	COG2076	Multidrug Resistance protein
KFS86_02125	COG4106	trans-aconitate 2-methyltransferase activity
KFS86_02155	COG5001	Diguanylate cyclase
KFS86_02155	COG3300	MHYT domain
KFS86_02160	COG2146	nitrite reductase [NAD(P)H] activity
KFS86_02185	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KFS86_02190	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KFS86_02200	COG0667	Aldo Keto reductase
KFS86_02225	COG3384	dioxygenase
KFS86_02235	COG1573	uracil-dna glycosylase
KFS86_02240	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
KFS86_02250	COG0025	NhaP-type Na H and K H
KFS86_02255	COG1131	(ABC) transporter
KFS86_02260	COG0842	Transport permease protein
KFS86_02320	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KFS86_02345	COG2205	protein histidine kinase activity
KFS86_02345	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KFS86_02370	COG1187	pseudouridine synthase activity
KFS86_02380	COG1666	GTP binding
KFS86_02385	COG0697	spore germination
KFS86_02390	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KFS86_02425	COG0508	dehydrogenase complex catalyzes the overall conversion of
KFS86_02430	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KFS86_02445	COG0356	it plays a direct role in the translocation of protons across the membrane
KFS86_02455	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KFS86_02465	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KFS86_02480	COG0355	proton-transporting ATP synthase activity, rotational mechanism
KFS86_02495	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KFS86_02505	COG4191	Histidine kinase
KFS86_02530	COG1136	(ABC) transporter
KFS86_02530	COG0577	efflux transmembrane transporter activity
KFS86_02535	COG1136	(ABC) transporter
KFS86_02535	COG0577	efflux transmembrane transporter activity
KFS86_02540	COG1136	(ABC) transporter
KFS86_02550	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KFS86_02565	COG2132	Multicopper oxidase
KFS86_02580	COG2217	Heavy metal translocating P-type atpase
KFS86_02590	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KFS86_02595	COG0339	signal peptide processing
KFS86_02620	COG0546	phosphoglycolate phosphatase activity
KFS86_02630	COG4206	TonB-dependent receptor
KFS86_02640	COG1956	GAF domain-containing protein
KFS86_02645	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
KFS86_02655	COG0720	synthase
KFS86_02660	COG0513	Belongs to the DEAD box helicase family
KFS86_02670	COG0625	glutathione transferase activity
KFS86_02700	COG0626	cystathionine gamma-synthase activity
KFS86_02715	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KFS86_02720	COG0438	transferase activity, transferring glycosyl groups
KFS86_02720	COG1216	Glycosyl transferase, family 2
KFS86_02725	COG1216	Glycosyl transferase, family 2
KFS86_02725	COG0438	transferase activity, transferring glycosyl groups
KFS86_02765	COG0493	'glutamate synthase
KFS86_02780	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KFS86_02785	COG0300	oxidoreductase activity
KFS86_02790	COG0277	FAD linked oxidase domain protein
KFS86_02795	COG0546	phosphoglycolate phosphatase activity
KFS86_02795	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
KFS86_02810	COG2086	electron transfer activity
KFS86_02835	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
KFS86_02835	COG0662	Cupin 2, conserved barrel domain protein
KFS86_02840	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KFS86_02845	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KFS86_02875	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
KFS86_02875	COG3218	ABC-type transport auxiliary lipoprotein component
KFS86_02880	COG1127	ABC transporter
KFS86_02885	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
KFS86_02900	COG0442	prolyl-tRNA aminoacylation
KFS86_02910	COG1183	phosphatidylcholine synthase activity
KFS86_02945	COG2927	DNA polymerase III (CHI subunit)
KFS86_02950	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KFS86_02975	COG4974	Belongs to the 'phage' integrase family
KFS86_02980	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KFS86_02985	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KFS86_02985	COG0047	phosphoribosylformylglycinamidine synthase activity
KFS86_02990	COG0840	transmembrane signaling receptor activity
KFS86_03000	COG5295	Hep Hag repeat protein
KFS86_03005	COG1404	Belongs to the peptidase S8 family
KFS86_03010	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KFS86_03015	COG1459	type II secretion system
KFS86_03020	COG2165	general secretion pathway protein
KFS86_03025	COG4970	Tfp pilus assembly protein FimT
KFS86_03030	COG2165	general secretion pathway protein
KFS86_03035	COG4795	General secretion pathway protein
KFS86_03040	COG3156	type II secretion system protein K
KFS86_03045	COG3166	PFAM Fimbrial assembly family protein
KFS86_03060	COG1450	Type ii and iii secretion system protein
KFS86_03070	COG2188	Transcriptional regulator
KFS86_03120	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KFS86_03130	COG1215	transferase activity, transferring glycosyl groups
KFS86_03150	COG1696	Membrane protein involved in D-alanine export
KFS86_03160	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KFS86_03170	COG1960	acyl-CoA dehydrogenase activity
KFS86_03185	COG0242	peptide deformylase activity
KFS86_03190	COG0488	(ABC) transporter
KFS86_03210	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KFS86_03220	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KFS86_03220	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KFS86_03235	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
KFS86_03240	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KFS86_03245	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
KFS86_03265	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
KFS86_03270	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
KFS86_03280	COG2205	protein histidine kinase activity
KFS86_03285	COG0745	RESPONSE REGULATOR receiver
KFS86_03290	COG0277	FAD linked oxidase domain protein
KFS86_03300	COG0792	nuclease activity
KFS86_03335	COG2001	Belongs to the MraZ family
KFS86_03340	COG0275	rRNA processing
KFS86_03345	COG3116	cell division
KFS86_03360	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KFS86_03385	COG1181	Belongs to the D-alanine--D-alanine ligase family
KFS86_03390	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KFS86_03400	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KFS86_03405	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
KFS86_03415	COG0739	heme binding
KFS86_03430	COG0494	nUDIX hydrolase
KFS86_03440	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KFS86_03505	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KFS86_03525	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KFS86_03545	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KFS86_03550	COG0667	Aldo Keto reductase
KFS86_03560	COG4771	TonB-dependent receptor
KFS86_03580	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
KFS86_03585	COG4181	ATPase activity
KFS86_03600	COG0642	Histidine kinase
KFS86_03610	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KFS86_03615	COG0861	Integral membrane protein TerC family
KFS86_03620	COG1704	LemA family
KFS86_03655	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KFS86_03660	COG2967	ApaG domain
KFS86_03665	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KFS86_03670	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
KFS86_03675	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KFS86_03680	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
KFS86_03690	COG2096	Adenosyltransferase
KFS86_03700	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KFS86_03705	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KFS86_03745	COG0697	spore germination
KFS86_03750	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KFS86_03780	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KFS86_03795	COG0583	DNA-binding transcription factor activity
KFS86_03800	COG3634	alkyl hydroperoxide reductase activity
KFS86_03870	COG0488	(ABC) transporter
KFS86_03925	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KFS86_03930	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
KFS86_03945	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KFS86_03955	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KFS86_03965	COG0193	aminoacyl-tRNA hydrolase activity
KFS86_03970	COG0012	GTP binding
KFS86_03990	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KFS86_04000	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KFS86_04005	COG0250	Participates in transcription elongation, termination and antitermination
KFS86_04010	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KFS86_04025	COG0222	ribosome binding
KFS86_04035	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KFS86_04050	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KFS86_04055	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KFS86_04060	COG0051	transcription antitermination factor activity, RNA binding
KFS86_04070	COG0088	Forms part of the polypeptide exit tunnel
KFS86_04075	COG0089	rRNA binding
KFS86_04080	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KFS86_04105	COG0255	Belongs to the universal ribosomal protein uL29 family
KFS86_04110	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KFS86_04120	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KFS86_04125	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KFS86_04130	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KFS86_04155	COG1841	ribosomal large subunit assembly
KFS86_04165	COG0201	protein transport
KFS86_04190	COG0203	ribosomal protein L17
KFS86_04195	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
KFS86_04205	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
KFS86_04220	COG1217	gtp-binding protein TYPA
KFS86_04225	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KFS86_04235	COG0039	L-malate dehydrogenase activity
KFS86_04250	COG0625	glutathione transferase activity
KFS86_04295	COG1902	pentaerythritol trinitrate reductase activity
KFS86_04295	COG0446	pyridine nucleotide-disulphide oxidoreductase
KFS86_04310	COG0667	Aldo Keto reductase
KFS86_04330	COG2885	chlorophyll binding
KFS86_04340	COG1187	pseudouridine synthase activity
KFS86_04345	COG0156	8-amino-7-oxononanoate synthase activity
KFS86_04350	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
KFS86_04355	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
KFS86_04360	COG4208	sulfate ABC transporter
KFS86_04365	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
KFS86_04385	COG0588	phosphoglycerate mutase activity
KFS86_04390	COG0285	dihydrofolate synthase activity
KFS86_04410	COG2833	Protein of unknown function (DUF455)
KFS86_04420	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KFS86_04430	COG0438	transferase activity, transferring glycosyl groups
KFS86_04435	COG0248	Ppx GppA phosphatase
KFS86_04440	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KFS86_04455	COG4783	chaperone-mediated protein folding
KFS86_04470	COG0473	3-isopropylmalate dehydrogenase activity
KFS86_04515	COG0544	peptidyl-prolyl cis-trans isomerase activity
KFS86_04525	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KFS86_04560	COG3942	CHAP domain
KFS86_04560	COG1388	LysM domain
KFS86_04565	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KFS86_04575	COG0328	RNA-DNA hybrid ribonuclease activity
KFS86_04580	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KFS86_04585	COG0631	protein serine/threonine phosphatase activity
KFS86_04605	COG0859	PFAM glycosyl transferase family 9
KFS86_04615	COG1234	tRNA 3'-trailer cleavage
KFS86_04620	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KFS86_04630	COG0315	cyclic pyranopterin monophosphate synthase activity
KFS86_04635	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
KFS86_04640	COG0314	molybdopterin synthase activity
KFS86_04755	COG0537	adenosine 5'-monophosphoramidase activity
KFS86_04775	COG0714	Associated with various cellular activities
KFS86_04800	COG1399	metal-binding, possibly nucleic acid-binding protein
KFS86_04810	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KFS86_04815	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KFS86_04820	COG1028	Short-chain dehydrogenase reductase Sdr
KFS86_04825	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KFS86_04835	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KFS86_04840	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KFS86_04845	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KFS86_04865	COG4115	mRNA cleavage
KFS86_04870	COG2161	toxin-antitoxin pair type II binding
KFS86_04915	COG0372	Belongs to the citrate synthase family
KFS86_04935	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KFS86_04990	COG2373	Large extracellular alpha-helical protein
KFS86_05010	COG4953	penicillin-binding protein 1C
KFS86_05020	COG0678	peroxiredoxin activity
KFS86_05040	COG0604	alcohol dehydrogenase
KFS86_05045	COG0330	HflC and HflK could
KFS86_05050	COG0330	HflC and HflK could
KFS86_05060	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KFS86_05180	COG3459	Glycosyltransferase 36 associated
KFS86_05190	COG1063	alcohol dehydrogenase
KFS86_05215	COG0753	catalase activity
KFS86_05230	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KFS86_05230	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KFS86_05255	COG2814	Major facilitator Superfamily
KFS86_05300	COG2194	sulfuric ester hydrolase activity
KFS86_05310	COG0745	RESPONSE REGULATOR receiver
KFS86_05315	COG2205	protein histidine kinase activity
KFS86_05325	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
KFS86_05330	COG2894	cell division
KFS86_05335	COG0850	regulation of cytokinetic process
KFS86_05345	COG4585	Histidine kinase
KFS86_05365	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KFS86_05375	COG1216	Glycosyl transferase, family 2
KFS86_05380	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KFS86_05390	COG1199	ATP-dependent helicase activity
KFS86_05415	COG0189	ligase activity
KFS86_05430	COG0835	chemotaxis
KFS86_05435	COG0840	transmembrane signaling receptor activity
KFS86_05440	COG0643	Histidine kinase
KFS86_05440	COG0784	Response regulator, receiver
KFS86_05440	COG2198	Histidine kinase
KFS86_05445	COG2201	protein-glutamate methylesterase activity
KFS86_05475	COG1446	asparaginase
KFS86_05480	COG3142	Participates in the control of copper homeostasis
KFS86_05520	COG0217	transcriptional regulatory protein
KFS86_05530	COG0632	four-way junction helicase activity
KFS86_05535	COG3158	transport of potassium into the cell
KFS86_05540	COG2255	four-way junction helicase activity
KFS86_05545	COG0824	Thioesterase
KFS86_05555	COG0848	biopolymer transport protein
KFS86_05570	COG2885	chlorophyll binding
KFS86_05580	COG0602	queuosine metabolic process
KFS86_05585	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KFS86_05605	COG0514	ATP-dependent DNA helicase (RecQ)
KFS86_05610	COG0783	Belongs to the Dps family
KFS86_05615	COG1643	Atp-dependent helicase
KFS86_05660	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KFS86_05725	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
KFS86_05740	COG1946	Acyl-CoA thioesterase
KFS86_05745	COG1024	Enoyl-CoA hydratase
KFS86_05755	COG0824	Thioesterase
KFS86_05760	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KFS86_05765	COG0261	This protein binds to 23S rRNA in the presence of protein L20
KFS86_05770	COG0211	Belongs to the bacterial ribosomal protein bL27 family
KFS86_05775	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KFS86_05785	COG0728	peptidoglycan biosynthetic process
KFS86_05800	COG0196	riboflavin kinase activity
KFS86_05815	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
KFS86_05845	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KFS86_05850	COG1845	cytochrome c oxidase, subunit III
KFS86_05855	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
KFS86_05865	COG0156	8-amino-7-oxononanoate synthase activity
KFS86_05895	COG1595	DNA-templated transcription, initiation
KFS86_05920	COG0745	RESPONSE REGULATOR receiver
KFS86_05950	COG4794	Type iii secretion
KFS86_05975	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KFS86_06020	COG2207	Transcriptional regulator
KFS86_06050	COG0129	dihydroxy-acid dehydratase activity
KFS86_06075	COG1012	belongs to the aldehyde dehydrogenase family
KFS86_06080	COG1879	ABC-type sugar transport system periplasmic component
KFS86_06085	COG1129	ABC transporter
KFS86_06090	COG1172	Belongs to the binding-protein-dependent transport system permease family
KFS86_06095	COG1172	Belongs to the binding-protein-dependent transport system permease family
KFS86_06105	COG1082	Xylose isomerase domain protein TIM barrel
KFS86_06110	COG0625	glutathione transferase activity
KFS86_06120	COG0475	glutathione-regulated potassium exporter activity
KFS86_06145	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KFS86_06150	COG2070	2-Nitropropane dioxygenase
KFS86_06165	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KFS86_06170	COG0336	Belongs to the RNA methyltransferase TrmD family
KFS86_06175	COG0335	large ribosomal subunit rRNA binding
KFS86_06180	COG0534	Mate efflux family protein
KFS86_06190	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
KFS86_06220	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KFS86_06235	COG2855	membrane
KFS86_06255	COG1250	3-hydroxyacyl-CoA dehydrogenase
KFS86_06255	COG1024	Enoyl-CoA hydratase
KFS86_06270	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KFS86_06275	COG0481	GTPase activity
KFS86_06280	COG0681	Belongs to the peptidase S26 family
KFS86_06295	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KFS86_06305	COG0745	RESPONSE REGULATOR receiver
KFS86_06315	COG2954	triphosphatase activity
KFS86_06325	COG1472	Belongs to the glycosyl hydrolase 3 family
KFS86_06330	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
KFS86_06335	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
KFS86_06340	COG1278	Cold shock
KFS86_06345	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KFS86_06355	COG1201	RNA secondary structure unwinding
KFS86_06360	COG1793	dna ligase
KFS86_06360	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
KFS86_06365	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
KFS86_06365	COG1793	dna ligase
KFS86_06395	COG0443	Heat shock 70 kDa protein
KFS86_06405	COG0183	Belongs to the thiolase family
KFS86_06435	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
KFS86_06435	COG1703	isobutyryl-CoA mutase activity
KFS86_06435	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
KFS86_06500	COG3250	beta-galactosidase activity
KFS86_06505	COG2186	Transcriptional regulator
KFS86_06515	COG0784	Response regulator, receiver
KFS86_06515	COG2198	Histidine kinase
KFS86_06515	COG2205	protein histidine kinase activity
KFS86_06535	COG1451	nucleotide metabolic process
KFS86_06545	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KFS86_06580	COG1077	Cell shape determining protein MreB Mrl
KFS86_06585	COG1047	Peptidyl-prolyl cis-trans
KFS86_06590	COG2824	Alkylphosphonate utilization operon protein PhnA
KFS86_06595	COG1902	pentaerythritol trinitrate reductase activity
KFS86_06600	COG2814	Major facilitator Superfamily
KFS86_06630	COG0392	lysyltransferase activity
KFS86_06630	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KFS86_06640	COG0251	oxidation-reduction process
KFS86_06660	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KFS86_06685	COG1595	DNA-templated transcription, initiation
KFS86_06700	COG2878	Part of a membrane complex involved in electron transport
KFS86_06720	COG0346	lactoylglutathione lyase activity
KFS86_06730	COG0833	amino acid
KFS86_06735	COG2040	homocysteine
KFS86_06745	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
KFS86_06760	COG3118	belongs to the thioredoxin family
KFS86_06770	COG0495	leucyl-tRNA aminoacylation
KFS86_06785	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KFS86_06800	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KFS86_06815	COG2968	Membrane
KFS86_06835	COG0312	modulator of DNA gyrase
KFS86_06845	COG0312	modulator of DNA gyrase
KFS86_06935	COG0631	protein serine/threonine phosphatase activity
KFS86_06940	COG0515	serine threonine protein kinase
KFS86_06940	COG2815	serine threonine protein kinase
KFS86_06965	COG1858	cytochrome C peroxidase
KFS86_06975	COG0142	geranyltranstransferase activity
KFS86_06980	COG1722	exodeoxyribonuclease VII activity
KFS86_06985	COG0037	tRNA processing
KFS86_06995	COG1785	Belongs to the alkaline phosphatase family
KFS86_07000	COG1301	dicarboxylic acid transport
KFS86_07010	COG1607	acyl-coa hydrolase
KFS86_07025	COG0791	NLP P60 protein
KFS86_07030	COG0791	NLP P60 protein
KFS86_07035	COG1047	Peptidyl-prolyl cis-trans
KFS86_07040	COG2311	Membrane
KFS86_07045	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KFS86_07065	COG0697	spore germination
KFS86_07105	COG3590	peptidase
KFS86_07120	COG0457	Tetratricopeptide repeat
KFS86_07125	COG4771	TonB-dependent receptor
KFS86_07135	COG4771	TonB-dependent receptor
KFS86_07145	COG0489	protein tyrosine kinase activity
KFS86_07150	COG0717	Belongs to the dCTP deaminase family
KFS86_07155	COG1714	RDD family
KFS86_07175	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KFS86_07190	COG0494	nUDIX hydrolase
KFS86_07195	COG0433	COG0433 Predicted ATPase
KFS86_07200	COG0741	lytic transglycosylase activity
KFS86_07205	COG0688	phosphatidylethanolamine metabolic process
KFS86_07215	COG2890	protein-(glutamine-N5) methyltransferase activity
KFS86_07280	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KFS86_07310	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KFS86_07320	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KFS86_07325	COG0649	NAD binding
KFS86_07330	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
KFS86_07335	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
KFS86_07375	COG1007	ATP synthesis coupled electron transport
KFS86_07390	COG0195	Participates in both transcription termination and antitermination
KFS86_07405	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KFS86_07415	COG1185	polyribonucleotide nucleotidyltransferase activity
KFS86_07420	COG3300	MHYT domain
KFS86_07420	COG5001	Diguanylate cyclase
KFS86_07440	COG0840	transmembrane signaling receptor activity
KFS86_07445	COG0840	transmembrane signaling receptor activity
KFS86_07450	COG0835	chemotaxis
KFS86_07495	COG1194	a g-specific adenine glycosylase
KFS86_07500	COG0552	protein localization to endoplasmic reticulum
KFS86_07510	COG3938	Belongs to the proline racemase family
KFS86_07515	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KFS86_07530	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KFS86_07540	COG0006	proline dipeptidase activity
KFS86_07555	COG0531	amino acid
KFS86_07590	COG3507	Belongs to the glycosyl hydrolase 43 family
KFS86_07600	COG4771	TonB-dependent receptor
KFS86_07625	COG0742	ribosomal rna small subunit methyltransferase
KFS86_07640	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
KFS86_07645	COG0405	Gamma-glutamyltransferase
KFS86_07650	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KFS86_07655	COG3291	Pkd domain containing protein
KFS86_07660	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KFS86_07670	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KFS86_07680	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KFS86_07690	COG1862	Preprotein translocase
KFS86_07695	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KFS86_07720	COG3706	GGDEF domain
KFS86_07720	COG2203	Gaf domain
KFS86_07720	COG4251	negative regulation of phosphorylation
KFS86_07720	COG5001	Diguanylate cyclase
KFS86_07725	COG1509	lysine 2,3-aminomutase activity
KFS86_07735	COG3548	integral membrane protein
KFS86_07740	COG0402	S-adenosylhomocysteine deaminase activity
KFS86_07770	COG4677	pectinesterase activity
KFS86_07775	COG3547	Transposase (IS116 IS110 IS902 family)
KFS86_07805	COG2850	peptidyl-arginine hydroxylation
KFS86_07845	COG1131	(ABC) transporter
KFS86_07850	COG1725	Transcriptional regulator
KFS86_07860	COG0386	Belongs to the glutathione peroxidase family
KFS86_07875	COG2900	Belongs to the SlyX family
KFS86_07885	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
KFS86_07885	COG2755	lipolytic protein G-D-S-L family
KFS86_07895	COG0646	methionine synthase
KFS86_07895	COG1410	methionine synthase
KFS86_07900	COG0646	methionine synthase
KFS86_07900	COG1410	methionine synthase
KFS86_07905	COG2226	methyltransferase
KFS86_07910	COG1960	acyl-CoA dehydrogenase activity
KFS86_07915	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KFS86_07920	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KFS86_07930	COG2902	Dehydrogenase
KFS86_07980	COG2925	Exonuclease
KFS86_07990	COG3844	kynureninase activity
KFS86_07995	COG1289	transmembrane transporter activity
KFS86_08005	COG0288	reversible hydration of carbon dioxide
KFS86_08075	COG0316	Belongs to the HesB IscA family
KFS86_08110	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KFS86_08120	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
KFS86_08130	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
KFS86_08165	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
KFS86_08180	COG1228	amidohydrolase
KFS86_08195	COG4221	oxidoreductase activity
KFS86_08235	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KFS86_08240	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KFS86_08245	COG1605	Chorismate mutase
KFS86_08245	COG0077	Prephenate dehydratase
KFS86_08270	COG0583	DNA-binding transcription factor activity
KFS86_08325	COG1136	(ABC) transporter
KFS86_08325	COG0577	efflux transmembrane transporter activity
KFS86_08355	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KFS86_08355	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KFS86_08360	COG1105	Belongs to the carbohydrate kinase PfkB family
KFS86_08365	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KFS86_08365	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
KFS86_08370	COG1609	Transcriptional regulator
KFS86_08380	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
KFS86_08385	COG0069	glutamate synthase activity
KFS86_08420	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KFS86_08435	COG1253	flavin adenine dinucleotide binding
KFS86_08445	COG0306	phosphate transporter
KFS86_08465	COG0504	CTP synthase activity
KFS86_08480	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
KFS86_08485	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
KFS86_08490	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
KFS86_08505	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
KFS86_08515	COG1238	metal cluster binding
KFS86_08530	COG1534	Rna-binding protein
KFS86_08535	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
KFS86_08540	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KFS86_08550	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KFS86_08555	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KFS86_08565	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KFS86_08570	COG1546	Belongs to the CinA family
KFS86_08575	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
KFS86_08580	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KFS86_08585	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KFS86_08590	COG2137	regulation of response to DNA damage stimulus
KFS86_08640	COG1294	oxidase, subunit
KFS86_08650	COG4988	ABC transporter
KFS86_08655	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KFS86_08660	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KFS86_08710	COG4133	protoheme IX ABC transporter activity
KFS86_08715	COG0436	Aminotransferase
KFS86_08740	COG1187	pseudouridine synthase activity
KFS86_08745	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KFS86_08750	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KFS86_08755	COG2350	Protein conserved in bacteria
KFS86_08790	COG0395	ABC-type sugar transport system, permease component
KFS86_08805	COG0129	dihydroxy-acid dehydratase activity
KFS86_08820	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KFS86_08825	COG3842	ATPase activity
KFS86_08840	COG2009	succinate dehydrogenase
KFS86_08845	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
KFS86_08860	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
KFS86_08870	COG4591	ABC-type transport system involved in lipoprotein release permease component
KFS86_08890	COG0811	peptide transport
KFS86_08900	COG1132	(ABC) transporter
KFS86_08905	COG1663	tetraacyldisaccharide 4'-kinase activity
KFS86_08915	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KFS86_08930	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KFS86_08945	COG2963	transposase activity
KFS86_08950	COG2801	Transposase and inactivated derivatives
KFS86_09105	COG3179	chitinase
KFS86_09260	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
KFS86_09265	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KFS86_09275	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KFS86_09310	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KFS86_09315	COG2258	MOSC domain
KFS86_09325	COG0505	Belongs to the CarA family
KFS86_09335	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
KFS86_09340	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KFS86_09350	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KFS86_09445	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
KFS86_09465	COG1024	Enoyl-CoA hydratase
KFS86_09475	COG1024	Enoyl-CoA hydratase
KFS86_09480	COG1024	Enoyl-CoA hydratase
KFS86_09515	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KFS86_09530	COG0346	lactoylglutathione lyase activity
KFS86_09540	COG1304	FMN binding
KFS86_09545	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KFS86_09550	COG1649	PFAM Uncharacterised BCR, COG1649
KFS86_09625	COG2183	response to ionizing radiation
KFS86_09630	COG0784	Response regulator, receiver
KFS86_09630	COG4191	Histidine kinase
KFS86_09640	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
KFS86_09640	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KFS86_09660	COG3243	poly(R)-hydroxyalkanoic acid synthase
KFS86_09670	COG1183	phosphatidylcholine synthase activity
KFS86_09675	COG1028	Short-chain dehydrogenase reductase Sdr
KFS86_09690	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
KFS86_09700	COG0668	transmembrane transport
KFS86_09705	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
KFS86_09720	COG1914	H( )-stimulated, divalent metal cation uptake system
KFS86_09730	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
KFS86_09735	COG1501	Belongs to the glycosyl hydrolase 31 family
KFS86_09790	COG4691	Plasmid stability protein
KFS86_09795	COG1487	ribonuclease activity
KFS86_09870	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KFS86_09870	COG0519	Catalyzes the synthesis of GMP from XMP
KFS86_09870	COG0519	Catalyzes the synthesis of GMP from XMP
KFS86_09870	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KFS86_09900	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KFS86_09900	COG0519	Catalyzes the synthesis of GMP from XMP
KFS86_09910	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KFS86_09930	COG0475	glutathione-regulated potassium exporter activity
KFS86_09930	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KFS86_09935	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KFS86_09945	COG0746	molybdenum cofactor guanylyltransferase activity
KFS86_09955	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KFS86_09965	COG1426	Protein conserved in bacteria
KFS86_09975	COG0820	rRNA (adenine-C2-)-methyltransferase activity
KFS86_09990	COG1250	3-hydroxyacyl-CoA dehydrogenase
KFS86_09990	COG1024	Enoyl-CoA hydratase
KFS86_09995	COG0183	Belongs to the thiolase family
KFS86_10000	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KFS86_10010	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KFS86_10015	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
KFS86_10025	COG0776	regulation of translation
KFS86_10030	COG0539	negative regulation of cytoplasmic translation
KFS86_10035	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
KFS86_10040	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KFS86_10050	COG2957	Belongs to the agmatine deiminase family
KFS86_10055	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KFS86_10075	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KFS86_10095	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
KFS86_10095	COG0316	Belongs to the HesB IscA family
KFS86_10110	COG0428	transporter
KFS86_10125	COG1530	ribonuclease E activity
KFS86_10150	COG2801	Transposase and inactivated derivatives
KFS86_10170	COG0512	Glutamine amidotransferase of anthranilate synthase
KFS86_10205	COG1022	Amp-dependent synthetase and ligase
KFS86_10210	COG2801	Transposase and inactivated derivatives
KFS86_10240	COG1132	(ABC) transporter
KFS86_10260	COG0438	transferase activity, transferring glycosyl groups
KFS86_10265	COG0438	transferase activity, transferring glycosyl groups
KFS86_10285	COG4106	trans-aconitate 2-methyltransferase activity
KFS86_10305	COG2244	polysaccharide biosynthetic process
KFS86_10335	COG3038	cytochrome b561
KFS86_10355	COG1595	DNA-templated transcription, initiation
KFS86_10410	COG0038	chloride channel
KFS86_10415	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KFS86_10435	COG1674	ftsk spoiiie
KFS86_10440	COG0492	ferredoxin-NADP+ reductase activity
KFS86_10460	COG0542	response to heat
KFS86_10480	COG0482	sulfurtransferase activity
KFS86_10485	COG2915	High frequency lysogenization protein hflD homolog
KFS86_10550	COG0835	chemotaxis
KFS86_10550	COG0784	Response regulator, receiver
KFS86_10560	COG1558	bacterial-type flagellum-dependent cell motility
KFS86_10570	COG1749	Flagellar hook protein flgE
KFS86_10585	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
KFS86_10600	COG1256	bacterial-type flagellum assembly
KFS86_10600	COG4786	Flagellar basal body rod
KFS86_10600	COG1256	bacterial-type flagellum assembly
KFS86_10600	COG4786	Flagellar basal body rod
KFS86_10605	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KFS86_10610	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KFS86_10615	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
KFS86_10635	COG2197	response regulator
KFS86_10640	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
KFS86_10645	COG2201	protein-glutamate methylesterase activity
KFS86_10665	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KFS86_10670	COG1028	Short-chain dehydrogenase reductase Sdr
KFS86_10675	COG1028	Short-chain dehydrogenase reductase Sdr
KFS86_10720	COG1677	Flagellar hook-basal body complex protein FliE
KFS86_10770	COG3190	flagellar
KFS86_10780	COG1987	bacterial-type flagellum assembly
KFS86_10785	COG1684	flagellar biosynthetic protein fliR
KFS86_10830	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
KFS86_10835	COG0643	Histidine kinase
KFS86_10835	COG0784	Response regulator, receiver
KFS86_10835	COG2198	Histidine kinase
KFS86_10840	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KFS86_10850	COG1192	Involved in chromosome partitioning
KFS86_10865	COG0745	RESPONSE REGULATOR receiver
KFS86_10880	COG0840	transmembrane signaling receptor activity
KFS86_10885	COG0840	transmembrane signaling receptor activity
KFS86_10890	COG0840	transmembrane signaling receptor activity
KFS86_10895	COG0840	transmembrane signaling receptor activity
KFS86_10905	COG0840	transmembrane signaling receptor activity
KFS86_10915	COG0840	transmembrane signaling receptor activity
KFS86_10920	COG0840	transmembrane signaling receptor activity
KFS86_10925	COG0840	transmembrane signaling receptor activity
KFS86_10940	COG0840	transmembrane signaling receptor activity
KFS86_10950	COG0835	chemotaxis
KFS86_10960	COG0840	transmembrane signaling receptor activity
KFS86_10970	COG0840	transmembrane signaling receptor activity
KFS86_10995	COG3706	GGDEF domain
KFS86_11025	COG0318	PFAM AMP-dependent synthetase and ligase
KFS86_11030	COG1024	Enoyl-CoA hydratase
KFS86_11035	COG0784	Response regulator, receiver
KFS86_11035	COG2205	protein histidine kinase activity
KFS86_11035	COG2198	Histidine kinase
KFS86_11070	COG0800	Aldolase
KFS86_11085	COG3734	2-keto-3-deoxy-galactonokinase
KFS86_11090	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
KFS86_11100	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KFS86_11110	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KFS86_11115	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
KFS86_11130	COG0351	phosphomethylpyrimidine kinase
KFS86_11130	COG0352	thiamine-phosphate diphosphorylase activity
KFS86_11150	COG0583	DNA-binding transcription factor activity
KFS86_11155	COG1741	Belongs to the pirin family
KFS86_11210	COG1024	Enoyl-CoA hydratase
KFS86_11225	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KFS86_11245	COG0277	FAD linked oxidase domain protein
KFS86_11250	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KFS86_11265	COG0531	amino acid
KFS86_11270	COG0531	amino acid
KFS86_11275	COG0235	Class ii aldolase
KFS86_11280	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
KFS86_11285	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
KFS86_11300	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KFS86_11300	COG0140	phosphoribosyl-ATP diphosphatase activity
KFS86_11315	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KFS86_11325	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KFS86_11330	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KFS86_11335	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
KFS86_11345	COG0124	histidyl-tRNA synthetase
KFS86_11360	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KFS86_11390	COG1012	belongs to the aldehyde dehydrogenase family
KFS86_11405	COG0167	dihydroorotate dehydrogenase activity
KFS86_11410	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KFS86_11435	COG0671	phosphoesterase, PA-phosphatase related
KFS86_11450	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
KFS86_11525	COG0166	Belongs to the GPI family
KFS86_11540	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
KFS86_11550	COG0617	tRNA 3'-terminal CCA addition
KFS86_11570	COG0860	N-Acetylmuramoyl-L-alanine amidase
KFS86_11575	COG0477	Major facilitator Superfamily
KFS86_11580	COG2115	Belongs to the xylose isomerase family
KFS86_11585	COG1070	Carbohydrate kinase
KFS86_11595	COG1501	Belongs to the glycosyl hydrolase 31 family
KFS86_11620	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KFS86_11640	COG0165	Argininosuccinate lyase
KFS86_11645	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KFS86_11655	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
KFS86_11660	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KFS86_11665	COG0137	argininosuccinate synthase activity
KFS86_11670	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KFS86_11685	COG2166	iron-sulfur cluster assembly
KFS86_11715	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
KFS86_11750	COG1132	(ABC) transporter
KFS86_11760	COG1605	Chorismate mutase
KFS86_11760	COG0287	Prephenate dehydrogenase
KFS86_11765	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
KFS86_11770	COG0484	heat shock protein binding
KFS86_11775	COG0443	Heat shock 70 kDa protein
KFS86_11780	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KFS86_11785	COG1420	regulation of RNA biosynthetic process
KFS86_11790	COG0497	DNA recombination
KFS86_11795	COG0735	belongs to the Fur family
KFS86_11800	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KFS86_11810	COG2867	negative regulation of translational initiation
KFS86_11815	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
KFS86_11820	COG1404	Belongs to the peptidase S8 family
KFS86_11860	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KFS86_11875	COG0583	DNA-binding transcription factor activity
KFS86_11890	COG0415	Belongs to the DNA photolyase family
KFS86_11895	COG0305	Participates in initiation and elongation during chromosome replication
KFS86_11905	COG1960	acyl-CoA dehydrogenase activity
KFS86_11920	COG0084	hydrolase, TatD family'
KFS86_11925	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KFS86_11975	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KFS86_12000	COG0386	Belongs to the glutathione peroxidase family
KFS86_12015	COG1846	Transcriptional regulator
KFS86_12055	COG1472	Belongs to the glycosyl hydrolase 3 family
KFS86_12065	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KFS86_12070	COG4290	ribonuclease
KFS86_12085	COG0488	(ABC) transporter
KFS86_12090	COG0513	Belongs to the DEAD box helicase family
KFS86_12115	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
KFS86_12120	COG0657	acetylesterase activity
KFS86_12125	COG0625	glutathione transferase activity
KFS86_12135	COG0564	pseudouridine synthase activity
KFS86_12140	COG4681	YaeQ
KFS86_12145	COG2081	HI0933 family
KFS86_12165	COG1028	Short-chain dehydrogenase reductase Sdr
KFS86_12185	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KFS86_12190	COG0860	N-Acetylmuramoyl-L-alanine amidase
KFS86_12195	COG0802	atpase or kinase
KFS86_12200	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KFS86_12200	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
KFS86_12205	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KFS86_12210	COG1570	exodeoxyribonuclease VII activity
KFS86_12245	COG1960	acyl-CoA dehydrogenase activity
KFS86_12255	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KFS86_12275	COG0438	transferase activity, transferring glycosyl groups
KFS86_12285	COG0438	transferase activity, transferring glycosyl groups
KFS86_12290	COG0438	transferase activity, transferring glycosyl groups
KFS86_12340	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KFS86_12345	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KFS86_12355	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KFS86_12385	COG0556	nucleotide-excision repair
KFS86_12430	COG3275	phosphorelay sensor kinase activity
KFS86_12435	COG1611	Belongs to the LOG family
KFS86_12445	COG2095	MarC family integral membrane protein
KFS86_12450	COG1028	Short-chain dehydrogenase reductase Sdr
KFS86_12455	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
KFS86_12495	COG2969	positive regulation of protein catabolic process
KFS86_12500	COG0625	glutathione transferase activity
KFS86_12505	COG2857	Cytochrome c1
KFS86_12515	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KFS86_12520	COG0723	plastoquinol--plastocyanin reductase activity
KFS86_12525	COG0741	lytic transglycosylase activity
KFS86_12540	COG1702	phosphate starvation-inducible protein PhoH
KFS86_12555	COG4535	Mg2 and Co2 transporter CorC
KFS86_12570	COG1012	belongs to the aldehyde dehydrogenase family
KFS86_12575	COG1177	transmembrane transport
KFS86_12580	COG1176	ABC-type spermidine putrescine transport system, permease component I
KFS86_12585	COG3842	ATPase activity
KFS86_12610	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
KFS86_12620	COG0174	glutamine synthetase
KFS86_12625	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
KFS86_12630	COG0174	glutamine synthetase
KFS86_12635	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KFS86_12645	COG0477	Major facilitator Superfamily
KFS86_12660	COG0243	molybdopterin cofactor binding
KFS86_12670	COG2223	nitrite transmembrane transporter activity
KFS86_12690	COG1012	belongs to the aldehyde dehydrogenase family
KFS86_12695	COG1396	sequence-specific DNA binding
KFS86_12695	COG1917	Cupin 2, conserved barrel domain protein
KFS86_12700	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KFS86_12705	COG0686	Belongs to the AlaDH PNT family
KFS86_12725	COG2733	membrane
KFS86_12730	COG0784	Response regulator, receiver
KFS86_12730	COG2205	protein histidine kinase activity
KFS86_12730	COG5002	protein histidine kinase activity
KFS86_12785	COG1024	Enoyl-CoA hydratase
KFS86_12795	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KFS86_12800	COG0659	secondary active sulfate transmembrane transporter activity
KFS86_12820	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KFS86_12825	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KFS86_12835	COG0581	inorganic phosphate transmembrane transporter activity
KFS86_12845	COG0704	Plays a role in the regulation of phosphate uptake
KFS86_12865	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KFS86_12875	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KFS86_12885	COG0557	exoribonuclease II activity
KFS86_12920	COG2814	Major facilitator Superfamily
KFS86_12925	COG1566	PFAM secretion protein HlyD family protein
KFS86_12960	COG0367	asparagine synthase
KFS86_12970	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KFS86_12975	COG1393	Belongs to the ArsC family
KFS86_12990	COG0024	Methionine aminopeptidase
KFS86_13030	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KFS86_13040	COG0528	UMP kinase activity
KFS86_13050	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KFS86_13055	COG0575	Belongs to the CDS family
KFS86_13060	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
KFS86_13065	COG0750	zinc metalloprotease
KFS86_13070	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KFS86_13075	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KFS86_13085	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KFS86_13090	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KFS86_13115	COG1981	membrane
KFS86_13155	COG0583	DNA-binding transcription factor activity
KFS86_13160	COG3547	Transposase (IS116 IS110 IS902 family)
KFS86_13185	COG1132	(ABC) transporter
KFS86_13210	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KFS86_13235	COG1187	pseudouridine synthase activity
KFS86_13260	COG3547	Transposase (IS116 IS110 IS902 family)
KFS86_13345	COG2080	2 iron, 2 sulfur cluster binding
KFS86_13350	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
KFS86_13355	COG1529	Aldehyde oxidase and xanthine dehydrogenase
KFS86_13390	COG0735	belongs to the Fur family
KFS86_13430	COG2205	protein histidine kinase activity
KFS86_13440	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
KFS86_13460	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KFS86_13470	COG0643	Histidine kinase
KFS86_13470	COG2198	Histidine kinase
KFS86_13475	COG0840	transmembrane signaling receptor activity
KFS86_13480	COG0840	transmembrane signaling receptor activity
KFS86_13485	COG0840	transmembrane signaling receptor activity
KFS86_13490	COG0835	chemotaxis
KFS86_13495	COG5001	Diguanylate cyclase
KFS86_13495	COG4251	negative regulation of phosphorylation
KFS86_13495	COG3706	GGDEF domain
KFS86_13495	COG2203	Gaf domain
KFS86_13525	COG2211	Major facilitator Superfamily
KFS86_13560	COG1966	Carbon starvation protein
KFS86_13565	COG2879	small protein
KFS86_13570	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KFS86_13590	COG0823	Involved in the tonB-independent uptake of proteins
KFS86_13590	COG1506	peptidase
KFS86_13595	COG1297	OPT oligopeptide transporter protein
KFS86_13600	COG3104	oligopeptide transport
KFS86_13615	COG3550	peptidyl-serine autophosphorylation
KFS86_13620	COG0629	single-stranded DNA binding
KFS86_13625	COG0142	geranyltranstransferase activity
KFS86_13650	COG0527	aspartate kinase activity
KFS86_13655	COG0384	phenazine biosynthesis protein PhzF
KFS86_13665	COG1764	response to oxidative stress
KFS86_13680	COG0739	heme binding
KFS86_13695	COG0693	protein deglycase activity
KFS86_13710	COG0719	Fe-S assembly protein
KFS86_13715	COG0396	ATPase activity
KFS86_13720	COG0719	Fe-S assembly protein
KFS86_13725	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KFS86_13735	COG2146	nitrite reductase [NAD(P)H] activity
KFS86_13740	COG4774	siderophore transport
KFS86_13765	COG1477	protein flavinylation
KFS86_13770	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KFS86_13790	COG1555	photosystem II stabilization
KFS86_13805	COG3178	'Phosphotransferase
KFS86_13810	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KFS86_13820	COG0628	permease
KFS86_13845	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KFS86_13890	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
KFS86_13905	COG1137	ATPase activity
KFS86_13920	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KFS86_13930	COG1660	Displays ATPase and GTPase activities
KFS86_13940	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KFS86_13945	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KFS86_13950	COG2239	Acts as a magnesium transporter
KFS86_13970	COG1113	amino acid transport
KFS86_13980	COG0840	transmembrane signaling receptor activity
KFS86_14000	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KFS86_14015	COG0519	Catalyzes the synthesis of GMP from XMP
KFS86_14090	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KFS86_14095	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KFS86_14105	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KFS86_14110	COG2814	Major facilitator Superfamily
KFS86_14130	COG3038	cytochrome b561
KFS86_14145	COG1760	l-serine dehydratase
KFS86_14155	COG2267	carboxylic ester hydrolase activity
KFS86_14160	COG0460	homoserine dehydrogenase
KFS86_14160	COG0527	aspartate kinase activity
KFS86_14165	COG0626	cystathionine gamma-synthase activity
KFS86_14170	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KFS86_14180	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KFS86_14185	COG1272	protein, Hemolysin III
KFS86_14190	COG2982	Protein involved in outer membrane biogenesis
KFS86_14195	COG0517	IMP dehydrogenase activity
KFS86_14200	COG0463	Glycosyl transferase, family 2
KFS86_14205	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KFS86_14210	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KFS86_14220	COG4206	TonB-dependent receptor
KFS86_14240	COG1304	FMN binding
KFS86_14250	COG1657	PFAM Prenyltransferase squalene oxidase
KFS86_14255	COG0142	geranyltranstransferase activity
KFS86_14260	COG2124	cytochrome p450
KFS86_14265	COG1028	Short-chain dehydrogenase reductase Sdr
KFS86_14270	COG1141	Ferredoxin
KFS86_14275	COG2124	cytochrome p450
KFS86_14280	COG2124	cytochrome p450
KFS86_14310	COG0697	spore germination
KFS86_14345	COG0330	HflC and HflK could
KFS86_14350	COG1742	UPF0060 membrane protein
KFS86_14355	COG3956	TIGRFAM MazG family protein
KFS86_14360	COG1218	3'(2'),5'-bisphosphate nucleotidase
KFS86_14365	COG0494	nUDIX hydrolase
KFS86_14375	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KFS86_14385	COG0837	glucose binding
KFS86_14400	COG1388	LysM domain
KFS86_14400	COG3858	chitin binding
KFS86_14405	COG3525	Glycosyl hydrolase, family 20, catalytic domain
KFS86_14415	COG1472	Belongs to the glycosyl hydrolase 3 family
KFS86_14440	COG3537	Alpha-1,2-mannosidase
KFS86_14540	COG5297	Belongs to the glycosyl hydrolase family 6
KFS86_14545	COG0521	Mo-molybdopterin cofactor biosynthetic process
KFS86_14565	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KFS86_14570	COG1295	ribonuclease BN
KFS86_14605	COG1404	Belongs to the peptidase S8 family
KFS86_14610	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KFS86_14650	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
KFS86_14670	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KFS86_14670	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KFS86_14725	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KFS86_14725	COG4651	solute:proton antiporter activity
KFS86_14735	COG4772	TonB-dependent receptor
KFS86_14745	COG4264	IucA IucC family
KFS86_14750	COG2814	Major facilitator Superfamily
KFS86_14755	COG4264	IucA IucC family
KFS86_14760	COG0019	diaminopimelate decarboxylase activity
KFS86_14785	COG0542	response to heat
KFS86_14835	COG3387	PFAM Glycoside hydrolase 15-related
KFS86_14860	COG0564	pseudouridine synthase activity
KFS86_14865	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KFS86_14875	COG1125	glycine betaine transport
KFS86_14880	COG1174	glycine betaine transport
KFS86_14895	COG1262	PFAM Formylglycine-generating sulfatase enzyme
KFS86_14905	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
KFS86_14905	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KFS86_14965	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
KFS86_14980	COG0745	RESPONSE REGULATOR receiver
KFS86_14990	COG0189	ligase activity
KFS86_15000	COG3511	phospholipase C
KFS86_15025	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KFS86_15040	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
KFS86_15050	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
KFS86_15055	COG0174	glutamine synthetase
KFS86_15075	COG2022	thiamine diphosphate biosynthetic process
KFS86_15085	COG3273	potassium ion transport
KFS86_15085	COG0471	metal ion transport
KFS86_15100	COG0179	Fumarylacetoacetate (FAA) hydrolase
KFS86_15120	COG1609	Transcriptional regulator
KFS86_15140	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KFS86_15150	COG1115	amino acid carrier protein
KFS86_15170	COG0840	transmembrane signaling receptor activity
KFS86_15175	COG2895	sulfate adenylyltransferase (ATP) activity
KFS86_15175	COG0529	Catalyzes the synthesis of activated sulfate
KFS86_15185	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KFS86_15190	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KFS86_15195	COG0175	sulfate reduction
KFS86_15225	COG1393	Belongs to the ArsC family
KFS86_15230	COG2198	Histidine kinase
KFS86_15230	COG2205	protein histidine kinase activity
KFS86_15230	COG0784	Response regulator, receiver
KFS86_15245	COG1648	precorrin-2 dehydrogenase activity
KFS86_15245	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KFS86_15260	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KFS86_15295	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
KFS86_15300	COG3588	fructose-bisphosphate aldolase
KFS86_15305	COG0469	pyruvate kinase activity
KFS86_15350	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KFS86_15355	COG3047	cAMP biosynthetic process
KFS86_15380	COG0640	Transcriptional regulator
KFS86_15390	COG0725	ABC transporter, periplasmic molybdate-binding protein
KFS86_15395	COG4149	molybdate abc transporter
KFS86_15400	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
KFS86_15435	COG1376	ErfK ybiS ycfS ynhG family protein
KFS86_15440	COG0739	heme binding
KFS86_15470	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KFS86_15475	COG1301	dicarboxylic acid transport
KFS86_15505	COG0714	Associated with various cellular activities
KFS86_15535	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
KFS86_15550	COG0372	Belongs to the citrate synthase family
KFS86_15555	COG0254	rRNA binding
KFS86_15565	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KFS86_15575	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KFS86_15580	COG1758	RNA polymerase activity
KFS86_15585	COG0194	GDP metabolic process
KFS86_15590	COG1561	YicC-like family, N-terminal region
KFS86_15595	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
KFS86_15600	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KFS86_15605	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KFS86_15625	COG0006	proline dipeptidase activity
KFS86_15630	COG0006	proline dipeptidase activity
KFS86_15635	COG3079	Belongs to the UPF0149 family
KFS86_15660	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KFS86_15670	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KFS86_15685	COG1773	rubredoxin
KFS86_15710	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
KFS86_15730	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KFS86_15740	COG1940	carbohydrate kinase activity
KFS86_15755	COG0671	phosphoesterase, PA-phosphatase related
KFS86_15765	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KFS86_15785	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
KFS86_15795	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
KFS86_15820	COG0840	transmembrane signaling receptor activity
KFS86_15825	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KFS86_15845	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KFS86_15865	COG0066	3-isopropylmalate dehydratase activity
KFS86_15870	COG0473	3-isopropylmalate dehydrogenase activity
KFS86_15875	COG3706	GGDEF domain
KFS86_15880	COG1309	transcriptional regulator
KFS86_15885	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
KFS86_15890	COG1538	Outer membrane efflux protein
KFS86_15895	COG1519	Transferase
KFS86_15900	COG1560	Kdo2-lipid A biosynthetic process
KFS86_15965	COG0280	phosphate acetyltransferase
KFS86_15965	COG0281	malic enzyme
KFS86_15970	COG1301	dicarboxylic acid transport
KFS86_15980	COG4191	Histidine kinase
KFS86_16000	COG0642	Histidine kinase
KFS86_16015	COG2851	Citrate transporter
KFS86_16020	COG1028	Short-chain dehydrogenase reductase Sdr
KFS86_16030	COG2211	Major facilitator Superfamily
KFS86_16055	COG1162	GTPase activity
KFS86_16175	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
KFS86_16195	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
KFS86_16240	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KFS86_16250	COG3791	Glutathione-dependent formaldehyde-activating
KFS86_16255	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
KFS86_16270	COG2205	protein histidine kinase activity
KFS86_16320	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KFS86_16340	COG0617	tRNA 3'-terminal CCA addition
KFS86_16350	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KFS86_16355	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KFS86_16360	COG1609	Transcriptional regulator
KFS86_16365	COG0738	Major facilitator superfamily
KFS86_16370	COG2188	Transcriptional regulator
KFS86_16385	COG3250	beta-galactosidase activity
KFS86_16395	COG4305	rare lipoprotein A
KFS86_16410	COG1028	Short-chain dehydrogenase reductase Sdr
KFS86_16415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KFS86_16425	COG4191	Histidine kinase
KFS86_16430	COG0784	Response regulator, receiver
KFS86_16435	COG2202	Pas domain
KFS86_16435	COG2205	protein histidine kinase activity
KFS86_16445	COG2823	Periplasmic or secreted lipoprotein
KFS86_16450	COG0673	inositol 2-dehydrogenase activity
KFS86_16455	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
KFS86_16465	COG1090	epimerase
KFS86_16485	COG1056	cytidyltransferase-related domain
KFS86_16485	COG1051	belongs to the nudix hydrolase family
KFS86_16515	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KFS86_16550	COG1686	Belongs to the peptidase S11 family
KFS86_16560	COG2951	lytic endotransglycosylase activity
KFS86_16580	COG0772	Belongs to the SEDS family
KFS86_16585	COG0768	penicillin binding
KFS86_16595	COG1792	Involved in formation and maintenance of cell shape
KFS86_16600	COG1077	Cell shape determining protein MreB Mrl
KFS86_16605	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KFS86_16610	COG3284	Transcriptional regulator
KFS86_16620	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
KFS86_16630	COG2010	Cytochrome c
KFS86_16655	COG0596	Alpha beta hydrolase
KFS86_16655	COG0508	dehydrogenase complex catalyzes the overall conversion of
KFS86_16660	COG0308	aminopeptidase N
KFS86_16665	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KFS86_16675	COG2226	methyltransferase
KFS86_16720	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KFS86_16730	COG2832	Protein of unknown function (DUF454)
KFS86_16740	COG0436	Aminotransferase
KFS86_16745	COG1505	serine-type exopeptidase activity
KFS86_16760	COG1733	regulation of RNA biosynthetic process
KFS86_16780	COG0181	hydroxymethylbilane synthase activity
KFS86_16825	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KFS86_16830	COG1640	4-alpha-glucanotransferase
KFS86_16855	COG0243	molybdopterin cofactor binding
KFS86_16860	COG2146	nitrite reductase [NAD(P)H] activity
KFS86_16865	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KFS86_16870	COG2223	nitrite transmembrane transporter activity
KFS86_16875	COG1116	anion transmembrane transporter activity
KFS86_16875	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KFS86_16905	COG3645	SOS response
KFS86_16915	COG0732	type I restriction modification DNA specificity domain
KFS86_16920	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
KFS86_16950	COG2204	response regulator
KFS86_16955	COG4191	Histidine kinase
KFS86_16960	COG0028	Belongs to the TPP enzyme family
KFS86_16975	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KFS86_16990	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
KFS86_17000	COG1028	Short-chain dehydrogenase reductase Sdr
KFS86_17005	COG3685	Protein conserved in bacteria
KFS86_17010	COG3685	Protein conserved in bacteria
KFS86_17015	COG3546	catalase activity
KFS86_17035	COG0840	transmembrane signaling receptor activity
KFS86_17075	COG1309	transcriptional regulator
KFS86_17160	COG4695	Portal protein
KFS86_17205	COG3179	chitinase
KFS86_17395	COG0366	Alpha amylase catalytic
KFS86_17400	COG0366	Alpha amylase catalytic
KFS86_17410	COG1609	Transcriptional regulator
KFS86_17445	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KFS86_17450	COG1490	D-aminoacyl-tRNA deacylase activity
KFS86_17465	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KFS86_17490	COG3307	-O-antigen
KFS86_17500	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KFS86_17505	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KFS86_17505	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KFS86_17510	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KFS86_17515	COG0242	peptide deformylase activity
KFS86_17520	COG1652	LysM domain
KFS86_17525	COG0758	DNA mediated transformation
KFS86_17540	COG1714	RDD family
KFS86_17545	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KFS86_17545	COG1754	DNA topoisomerase type I activity
KFS86_17550	COG0009	L-threonylcarbamoyladenylate synthase
KFS86_17565	COG1028	Short-chain dehydrogenase reductase Sdr
KFS86_17575	COG0616	signal peptide processing
KFS86_17580	COG0534	Mate efflux family protein
KFS86_17590	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KFS86_17600	COG1252	NADH dehydrogenase
KFS86_17605	COG2860	membrane
KFS86_17610	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KFS86_17615	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KFS86_17620	COG2201	protein-glutamate methylesterase activity
KFS86_17625	COG2177	Part of the ABC transporter FtsEX involved in
KFS86_17630	COG2884	Cell division ATP-binding protein ftsE
KFS86_17640	COG3118	belongs to the thioredoxin family
KFS86_17645	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KFS86_17675	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
KFS86_17725	COG1518	maintenance of DNA repeat elements
KFS86_17730	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KFS86_17740	COG1652	LysM domain
KFS86_17755	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KFS86_17760	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KFS86_17775	COG5383	Protein conserved in bacteria
KFS86_17810	COG3409	Peptidoglycan-binding domain 1 protein
KFS86_17810	COG3501	Rhs element vgr protein
KFS86_17850	COG4771	TonB-dependent receptor
KFS86_17860	COG4948	Mandelate Racemase Muconate Lactonizing
KFS86_17870	COG0531	amino acid
KFS86_17890	COG2133	pyrroloquinoline quinone binding
KFS86_17905	COG2308	Evidence 4 Homologs of previously reported genes of
KFS86_17925	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KFS86_17945	COG1295	ribonuclease BN
KFS86_17950	COG0358	DNA primase activity
KFS86_17965	COG0109	protoheme IX farnesyltransferase activity
KFS86_17995	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
KFS86_18000	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KFS86_18005	COG1565	acr, cog1565
KFS86_18005	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KFS86_18020	COG1486	melibiose metabolic process
KFS86_18065	COG0793	Belongs to the peptidase S41A family
KFS86_18070	COG4942	peptidase
KFS86_18080	COG2234	aminopeptidase activity
KFS86_18085	COG1064	alcohol dehydrogenase
KFS86_18115	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KFS86_18120	COG0739	heme binding
KFS86_18125	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
KFS86_18135	COG2814	Major facilitator Superfamily
KFS86_18145	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KFS86_18165	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KFS86_18185	COG4221	oxidoreductase activity
KFS86_18205	COG0583	DNA-binding transcription factor activity
KFS86_18210	COG2755	lipolytic protein G-D-S-L family
KFS86_18210	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
KFS86_18215	COG1819	glycosyl
KFS86_18220	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KFS86_18225	COG1166	arginine decarboxylase activity
KFS86_18240	COG2960	long-chain fatty acid transporting porin activity
KFS86_18245	COG0606	chelatase, subunit chli
KFS86_18275	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KFS86_18285	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
KFS86_18300	COG1028	Short-chain dehydrogenase reductase Sdr
KFS86_18320	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KFS86_18335	COG3706	GGDEF domain
KFS86_18335	COG4251	negative regulation of phosphorylation
KFS86_18335	COG5001	Diguanylate cyclase
KFS86_18335	COG2203	Gaf domain
KFS86_18345	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KFS86_18350	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KFS86_18365	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KFS86_18380	COG1522	sequence-specific DNA binding
KFS86_18415	COG0714	Associated with various cellular activities
KFS86_18425	COG0754	glutathionylspermidine amidase activity
KFS86_18470	COG2133	pyrroloquinoline quinone binding
KFS86_18480	COG0628	permease
KFS86_18505	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KFS86_18570	COG1199	ATP-dependent helicase activity
KFS86_18630	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
KFS86_18655	COG3104	oligopeptide transport
KFS86_18680	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KFS86_18695	COG0508	dehydrogenase complex catalyzes the overall conversion of
KFS86_18705	COG3227	Zinc metalloprotease (Elastase)
KFS86_18715	COG0513	Belongs to the DEAD box helicase family
KFS86_18745	COG2354	Protein conserved in bacteria
KFS86_18765	COG1196	nuclear chromosome segregation
KFS86_18765	COG3264	Mechanosensitive ion channel
KFS86_18775	COG0604	alcohol dehydrogenase
KFS86_18775	COG1028	Short-chain dehydrogenase reductase Sdr
KFS86_18775	COG3321	synthase
KFS86_18795	COG1595	DNA-templated transcription, initiation
KFS86_18810	COG0477	Major facilitator Superfamily
KFS86_18815	COG1802	Transcriptional regulator
KFS86_18860	COG1414	Transcriptional regulator
KFS86_18865	COG0738	Major facilitator superfamily
KFS86_18870	COG3254	rhamnose metabolic process
KFS86_18875	COG4948	Mandelate Racemase Muconate Lactonizing
KFS86_18880	COG0179	Fumarylacetoacetate (FAA) hydrolase
KFS86_18885	COG1028	Short-chain dehydrogenase reductase Sdr
KFS86_18915	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KFS86_18930	COG4807	Protein conserved in bacteria
KFS86_18950	COG4773	Receptor
KFS86_18965	COG1506	peptidase
KFS86_18965	COG0823	Involved in the tonB-independent uptake of proteins
KFS86_19050	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KFS86_19075	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KFS86_19080	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KFS86_19085	COG0753	catalase activity
KFS86_19110	COG1136	(ABC) transporter
KFS86_19115	COG0577	efflux transmembrane transporter activity
KFS86_19135	COG0697	spore germination
KFS86_19150	COG0180	Tryptophanyl-tRNA synthetase
KFS86_19185	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
KFS86_19190	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
KFS86_19190	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
KFS86_19200	COG3228	Belongs to the MtfA family
KFS86_19230	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KFS86_19255	COG2084	Dehydrogenase
KFS86_19260	COG1902	pentaerythritol trinitrate reductase activity
KFS86_19270	COG2814	Major facilitator Superfamily
KFS86_19275	COG0583	DNA-binding transcription factor activity
KFS86_19300	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KFS86_19305	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KFS86_19315	COG1764	response to oxidative stress
KFS86_19320	COG1846	Transcriptional regulator
KFS86_19325	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
KFS86_19335	COG0697	spore germination
KFS86_19340	COG0523	cobalamin synthesis protein
KFS86_19350	COG1742	UPF0060 membrane protein
KFS86_19360	COG3245	cytochrome
KFS86_19370	COG1960	acyl-CoA dehydrogenase activity
KFS86_19375	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KFS86_19390	COG1278	Cold shock
KFS86_19405	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KFS86_19410	COG3387	PFAM Glycoside hydrolase 15-related
KFS86_19415	COG0745	RESPONSE REGULATOR receiver
KFS86_19430	COG1404	Belongs to the peptidase S8 family
KFS86_19440	COG3100	YcgL domain-containing protein
KFS86_19445	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KFS86_19455	COG0463	Glycosyl transferase, family 2
KFS86_19490	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KFS86_19505	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KFS86_19530	COG1294	oxidase, subunit
KFS86_19535	COG1271	oxidase subunit
KFS86_19555	COG0408	coproporphyrinogen oxidase activity
KFS86_19565	COG2323	membrane
KFS86_19570	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KFS86_19570	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KFS86_19585	COG0589	response to stress
KFS86_19610	COG0210	DNA helicase
KFS86_19660	COG0463	Glycosyl transferase, family 2
KFS86_19670	COG1475	DNA binding
KFS86_19675	COG1192	Involved in chromosome partitioning
KFS86_19680	COG0357	Ribosomal RNA small subunit methyltransferase G
KFS86_19690	COG2091	lysine biosynthetic process via aminoadipic acid
KFS86_19715	COG0477	Major facilitator Superfamily
KFS86_19735	COG1971	Probably functions as a manganese efflux pump
KFS86_19740	COG2205	protein histidine kinase activity
KFS86_19750	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KFS86_19755	COG3459	Glycosyltransferase 36 associated
KFS86_19760	COG2211	Major facilitator Superfamily
KFS86_19765	COG3265	gluconokinase activity
KFS86_19780	COG2911	Protein conserved in bacteria
KFS86_19785	COG0729	surface antigen
KFS86_19805	COG3132	Protein of unknown function, DUF480
KFS86_19855	COG0284	orotidine-5'-phosphate decarboxylase activity
KFS86_19870	COG1609	Transcriptional regulator
KFS86_19880	COG2937	Belongs to the GPAT DAPAT family
KFS86_19905	COG2211	Major facilitator Superfamily
KFS86_19920	COG3693	PFAM glycoside hydrolase, family 10
KFS86_19925	COG1904	glucuronate isomerase
KFS86_19940	COG3386	PFAM SMP-30 Gluconolaconase
KFS86_19965	COG0246	Mannitol dehydrogenase
KFS86_19970	COG1472	Belongs to the glycosyl hydrolase 3 family
KFS86_19980	COG4948	Mandelate Racemase Muconate Lactonizing
KFS86_19990	COG3661	Belongs to the glycosyl hydrolase 67 family
KFS86_20000	COG2115	Belongs to the xylose isomerase family
KFS86_20005	COG0037	tRNA processing
KFS86_20025	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KFS86_20035	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KFS86_20045	COG0805	protein transport
KFS86_20055	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KFS86_20055	COG0519	Catalyzes the synthesis of GMP from XMP
KFS86_20060	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KFS86_20080	COG0210	DNA helicase
KFS86_20085	COG1435	thymidine kinase activity
KFS86_20095	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
KFS86_20110	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
KFS86_20125	COG1119	ATPase activity
KFS86_20135	COG0706	membrane insertase activity