locus-tag	class	description
KFS85_00010	COG0592	DNA-directed DNA polymerase activity
KFS85_00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KFS85_00020	COG0187	DNA topoisomerase II activity
KFS85_00025	COG1266	CAAX protease self-immunity
KFS85_00030	COG0501	Belongs to the peptidase M48B family
KFS85_00070	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KFS85_00095	COG2911	Protein conserved in bacteria
KFS85_00100	COG0729	surface antigen
KFS85_00120	COG3132	Protein of unknown function, DUF480
KFS85_00145	COG0284	orotidine-5'-phosphate decarboxylase activity
KFS85_00160	COG1609	Transcriptional regulator
KFS85_00170	COG2937	Belongs to the GPAT DAPAT family
KFS85_00195	COG2211	Major facilitator Superfamily
KFS85_00210	COG3693	PFAM glycoside hydrolase, family 10
KFS85_00215	COG1904	glucuronate isomerase
KFS85_00245	COG1280	lysine exporter protein (LysE YggA)
KFS85_00265	COG4772	TonB-dependent receptor
KFS85_00275	COG3284	Transcriptional regulator
KFS85_00280	COG1012	belongs to the aldehyde dehydrogenase family
KFS85_00315	COG1304	FMN binding
KFS85_00320	COG2186	Transcriptional regulator
KFS85_00340	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KFS85_00400	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KFS85_00425	COG4771	TonB-dependent receptor
KFS85_00460	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
KFS85_00475	COG3507	Belongs to the glycosyl hydrolase 43 family
KFS85_00480	COG1609	Transcriptional regulator
KFS85_00490	COG1028	Short-chain dehydrogenase reductase Sdr
KFS85_00505	COG3186	Phenylalanine-4-hydroxylase
KFS85_00510	COG1522	sequence-specific DNA binding
KFS85_00515	COG1752	Esterase of the alpha-beta hydrolase superfamily
KFS85_00530	COG0671	phosphoesterase, PA-phosphatase related
KFS85_00545	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KFS85_00580	COG1522	sequence-specific DNA binding
KFS85_00585	COG4771	TonB-dependent receptor
KFS85_00590	COG0531	amino acid
KFS85_00595	COG0154	amidase activity
KFS85_00680	COG0477	Major facilitator Superfamily
KFS85_00685	COG0302	gtp cyclohydrolase
KFS85_00710	COG0730	response to heat
KFS85_00730	COG2951	lytic endotransglycosylase activity
KFS85_00780	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KFS85_00785	COG1803	Methylglyoxal synthase
KFS85_00790	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
KFS85_00795	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
KFS85_00800	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
KFS85_00805	COG0493	'glutamate synthase
KFS85_00810	COG0070	glutamate synthase
KFS85_00810	COG0069	glutamate synthase activity
KFS85_00810	COG0067	glutamate synthase
KFS85_00865	COG1111	helicase
KFS85_00865	COG1205	dead DEAH box helicase
KFS85_00900	COG2271	Major facilitator Superfamily
KFS85_00955	COG1192	Involved in chromosome partitioning
KFS85_00960	COG2062	phosphohistidine phosphatase, SixA
KFS85_00970	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KFS85_00975	COG2050	protein possibly involved in aromatic compounds catabolism
KFS85_00985	COG2267	carboxylic ester hydrolase activity
KFS85_01005	COG1968	undecaprenyl-diphosphatase activity
KFS85_01010	COG0174	glutamine synthetase
KFS85_01015	COG0347	Belongs to the P(II) protein family
KFS85_01020	COG0004	ammonium transporteR
KFS85_01025	COG3852	Histidine kinase
KFS85_01030	COG2204	response regulator
KFS85_01035	COG2032	superoxide dismutase activity
KFS85_01040	COG2032	superoxide dismutase activity
KFS85_01055	COG0183	Belongs to the thiolase family
KFS85_01095	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
KFS85_01100	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
KFS85_01120	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KFS85_01130	COG0612	Peptidase, M16
KFS85_01140	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KFS85_01145	COG3177	Filamentation induced by cAMP protein fic
KFS85_01160	COG0596	Alpha beta hydrolase
KFS85_01170	COG0727	PFAM Uncharacterised protein family (UPF0153)
KFS85_01175	COG0318	PFAM AMP-dependent synthetase and ligase
KFS85_01190	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KFS85_01200	COG1181	Belongs to the D-alanine--D-alanine ligase family
KFS85_01220	COG4232	protein-disulfide reductase activity
KFS85_01225	COG0564	pseudouridine synthase activity
KFS85_01250	COG0681	Belongs to the peptidase S26 family
KFS85_01270	COG0583	DNA-binding transcription factor activity
KFS85_01275	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
KFS85_01280	COG2224	Isocitrate lyase
KFS85_01285	COG3706	GGDEF domain
KFS85_01315	COG0659	secondary active sulfate transmembrane transporter activity
KFS85_01345	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KFS85_01350	COG2130	NADP-dependent
KFS85_01365	COG1187	pseudouridine synthase activity
KFS85_01375	COG1643	Atp-dependent helicase
KFS85_01380	COG0084	hydrolase, TatD family'
KFS85_01395	COG0842	Transport permease protein
KFS85_01400	COG1131	(ABC) transporter
KFS85_01405	COG0543	2 iron, 2 sulfur cluster binding
KFS85_01405	COG0633	Ferredoxin
KFS85_01415	COG1476	TRANSCRIPTIONal
KFS85_01425	COG4555	ABC transporter
KFS85_01445	COG0625	glutathione transferase activity
KFS85_01495	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KFS85_01515	COG1199	ATP-dependent helicase activity
KFS85_01575	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KFS85_01595	COG0628	permease
KFS85_01640	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KFS85_01725	COG5463	Belongs to the UPF0441 family
KFS85_01730	COG0754	glutathionylspermidine amidase activity
KFS85_01740	COG0714	Associated with various cellular activities
KFS85_01775	COG1522	sequence-specific DNA binding
KFS85_01795	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KFS85_01810	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KFS85_01815	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KFS85_01835	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KFS85_01870	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
KFS85_01880	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KFS85_01940	COG0606	chelatase, subunit chli
KFS85_01945	COG2960	long-chain fatty acid transporting porin activity
KFS85_01970	COG1166	arginine decarboxylase activity
KFS85_01980	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KFS85_01985	COG1819	glycosyl
KFS85_01990	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
KFS85_01990	COG2755	lipolytic protein G-D-S-L family
KFS85_01995	COG0583	DNA-binding transcription factor activity
KFS85_02035	COG4221	oxidoreductase activity
KFS85_02060	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KFS85_02070	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KFS85_02080	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KFS85_02090	COG2814	Major facilitator Superfamily
KFS85_02100	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
KFS85_02105	COG0739	heme binding
KFS85_02110	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KFS85_02140	COG1064	alcohol dehydrogenase
KFS85_02145	COG2234	aminopeptidase activity
KFS85_02155	COG4942	peptidase
KFS85_02160	COG0793	Belongs to the peptidase S41A family
KFS85_02195	COG0531	amino acid
KFS85_02200	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
KFS85_02200	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
KFS85_02205	COG1486	melibiose metabolic process
KFS85_02220	COG1565	acr, cog1565
KFS85_02220	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KFS85_02225	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KFS85_02230	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
KFS85_02260	COG0109	protoheme IX farnesyltransferase activity
KFS85_02275	COG0358	DNA primase activity
KFS85_02280	COG1295	ribonuclease BN
KFS85_02300	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KFS85_02305	COG2308	Evidence 4 Homologs of previously reported genes of
KFS85_02320	COG2133	pyrroloquinoline quinone binding
KFS85_02350	COG0531	amino acid
KFS85_02360	COG4948	Mandelate Racemase Muconate Lactonizing
KFS85_02370	COG4771	TonB-dependent receptor
KFS85_02430	COG5383	Protein conserved in bacteria
KFS85_02450	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KFS85_02465	COG1652	LysM domain
KFS85_02475	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KFS85_02480	COG1518	maintenance of DNA repeat elements
KFS85_02530	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KFS85_02535	COG3118	belongs to the thioredoxin family
KFS85_02545	COG2884	Cell division ATP-binding protein ftsE
KFS85_02550	COG2177	Part of the ABC transporter FtsEX involved in
KFS85_02555	COG2201	protein-glutamate methylesterase activity
KFS85_02560	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KFS85_02565	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KFS85_02570	COG2860	membrane
KFS85_02575	COG1252	NADH dehydrogenase
KFS85_02580	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KFS85_02590	COG0534	Mate efflux family protein
KFS85_02595	COG0616	signal peptide processing
KFS85_02605	COG1028	Short-chain dehydrogenase reductase Sdr
KFS85_02625	COG0009	L-threonylcarbamoyladenylate synthase
KFS85_02630	COG1754	DNA topoisomerase type I activity
KFS85_02630	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KFS85_02635	COG1714	RDD family
KFS85_02650	COG0758	DNA mediated transformation
KFS85_02655	COG1652	LysM domain
KFS85_02660	COG0242	peptide deformylase activity
KFS85_02665	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KFS85_02670	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KFS85_02670	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KFS85_02675	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KFS85_02690	COG1215	transferase activity, transferring glycosyl groups
KFS85_02710	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KFS85_02725	COG1490	D-aminoacyl-tRNA deacylase activity
KFS85_02730	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KFS85_02745	COG1609	Transcriptional regulator
KFS85_02755	COG0366	Alpha amylase catalytic
KFS85_02760	COG0366	Alpha amylase catalytic
KFS85_02840	COG0596	Alpha beta hydrolase
KFS85_02855	COG1309	transcriptional regulator
KFS85_02890	COG0840	transmembrane signaling receptor activity
KFS85_02910	COG3685	Protein conserved in bacteria
KFS85_02915	COG3685	Protein conserved in bacteria
KFS85_02920	COG1028	Short-chain dehydrogenase reductase Sdr
KFS85_02930	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
KFS85_02945	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KFS85_02960	COG0028	Belongs to the TPP enzyme family
KFS85_02965	COG4191	Histidine kinase
KFS85_02970	COG2204	response regulator
KFS85_02995	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
KFS85_03000	COG0732	type I restriction modification DNA specificity domain
KFS85_03025	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KFS85_03025	COG1648	precorrin-2 dehydrogenase activity
KFS85_03030	COG0784	Response regulator, receiver
KFS85_03030	COG2198	Histidine kinase
KFS85_03030	COG2205	protein histidine kinase activity
KFS85_03035	COG1116	anion transmembrane transporter activity
KFS85_03035	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KFS85_03050	COG2223	nitrite transmembrane transporter activity
KFS85_03055	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KFS85_03060	COG2146	nitrite reductase [NAD(P)H] activity
KFS85_03065	COG0243	molybdopterin cofactor binding
KFS85_03115	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KFS85_03135	COG2204	response regulator
KFS85_03160	COG0181	hydroxymethylbilane synthase activity
KFS85_03175	COG1733	regulation of RNA biosynthetic process
KFS85_03190	COG1505	serine-type exopeptidase activity
KFS85_03195	COG0436	Aminotransferase
KFS85_03205	COG2832	Protein of unknown function (DUF454)
KFS85_03260	COG2226	methyltransferase
KFS85_03285	COG0308	aminopeptidase N
KFS85_03290	COG0508	dehydrogenase complex catalyzes the overall conversion of
KFS85_03290	COG0596	Alpha beta hydrolase
KFS85_03315	COG2010	Cytochrome c
KFS85_03325	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
KFS85_03335	COG3284	Transcriptional regulator
KFS85_03345	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KFS85_03350	COG1077	Cell shape determining protein MreB Mrl
KFS85_03365	COG0768	penicillin binding
KFS85_03370	COG0772	Belongs to the SEDS family
KFS85_03385	COG2951	lytic endotransglycosylase activity
KFS85_03395	COG1686	Belongs to the peptidase S11 family
KFS85_03410	COG0321	lipoyl(octanoyl) transferase activity
KFS85_03415	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KFS85_03445	COG1056	cytidyltransferase-related domain
KFS85_03445	COG1051	belongs to the nudix hydrolase family
KFS85_03480	COG1090	epimerase
KFS85_03490	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
KFS85_03495	COG0673	inositol 2-dehydrogenase activity
KFS85_03500	COG2823	Periplasmic or secreted lipoprotein
KFS85_03510	COG2202	Pas domain
KFS85_03510	COG2205	protein histidine kinase activity
KFS85_03515	COG0784	Response regulator, receiver
KFS85_03520	COG4191	Histidine kinase
KFS85_03530	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KFS85_03535	COG1028	Short-chain dehydrogenase reductase Sdr
KFS85_03550	COG4305	rare lipoprotein A
KFS85_03565	COG3250	beta-galactosidase activity
KFS85_03580	COG2188	Transcriptional regulator
KFS85_03590	COG1609	Transcriptional regulator
KFS85_03595	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KFS85_03600	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KFS85_03660	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KFS85_03685	COG2207	Transcriptional regulator
KFS85_03710	COG2205	protein histidine kinase activity
KFS85_03725	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
KFS85_03730	COG3791	Glutathione-dependent formaldehyde-activating
KFS85_03745	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KFS85_03755	COG0697	spore germination
KFS85_03770	COG1307	EDD domain protein, DegV family
KFS85_03770	COG1307	EDD domain protein, DegV family
KFS85_03785	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
KFS85_03790	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
KFS85_03810	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
KFS85_03835	COG0436	Aminotransferase
KFS85_03840	COG1162	GTPase activity
KFS85_03880	COG2211	Major facilitator Superfamily
KFS85_03890	COG1028	Short-chain dehydrogenase reductase Sdr
KFS85_03895	COG2851	Citrate transporter
KFS85_03910	COG0642	Histidine kinase
KFS85_03945	COG4191	Histidine kinase
KFS85_03955	COG1301	dicarboxylic acid transport
KFS85_03960	COG0280	phosphate acetyltransferase
KFS85_03960	COG0281	malic enzyme
KFS85_04035	COG1560	Kdo2-lipid A biosynthetic process
KFS85_04040	COG1519	Transferase
KFS85_04045	COG1538	Outer membrane efflux protein
KFS85_04050	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
KFS85_04060	COG3706	GGDEF domain
KFS85_04065	COG0473	3-isopropylmalate dehydrogenase activity
KFS85_04070	COG0066	3-isopropylmalate dehydratase activity
KFS85_04090	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KFS85_04115	COG0840	transmembrane signaling receptor activity
KFS85_04145	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
KFS85_04155	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
KFS85_04175	COG0563	adenylate kinase activity
KFS85_04185	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KFS85_04195	COG0671	phosphoesterase, PA-phosphatase related
KFS85_04210	COG1940	carbohydrate kinase activity
KFS85_04220	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KFS85_04260	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
KFS85_04275	COG1773	rubredoxin
KFS85_04290	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KFS85_04300	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KFS85_04325	COG3079	Belongs to the UPF0149 family
KFS85_04330	COG0006	proline dipeptidase activity
KFS85_04350	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KFS85_04355	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KFS85_04360	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
KFS85_04365	COG1561	YicC-like family, N-terminal region
KFS85_04370	COG0194	GDP metabolic process
KFS85_04375	COG1758	RNA polymerase activity
KFS85_04380	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KFS85_04400	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KFS85_04410	COG0254	rRNA binding
KFS85_04415	COG0372	Belongs to the citrate synthase family
KFS85_04430	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
KFS85_04460	COG0714	Associated with various cellular activities
KFS85_04490	COG1301	dicarboxylic acid transport
KFS85_04495	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KFS85_04525	COG0739	heme binding
KFS85_04530	COG1376	ErfK ybiS ycfS ynhG family protein
KFS85_04570	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
KFS85_04575	COG4149	molybdate abc transporter
KFS85_04580	COG0725	ABC transporter, periplasmic molybdate-binding protein
KFS85_04590	COG0640	Transcriptional regulator
KFS85_04610	COG3047	cAMP biosynthetic process
KFS85_04615	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KFS85_04660	COG0469	pyruvate kinase activity
KFS85_04665	COG3588	fructose-bisphosphate aldolase
KFS85_04670	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
KFS85_04715	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KFS85_04735	COG2072	flavoprotein involved in K transport
KFS85_04740	COG2351	hydroxyisourate hydrolase activity
KFS85_04750	COG1529	Aldehyde oxidase and xanthine dehydrogenase
KFS85_04780	COG1648	precorrin-2 dehydrogenase activity
KFS85_04780	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KFS85_04800	COG2205	protein histidine kinase activity
KFS85_04800	COG2198	Histidine kinase
KFS85_04800	COG0784	Response regulator, receiver
KFS85_04810	COG1393	Belongs to the ArsC family
KFS85_04840	COG0175	sulfate reduction
KFS85_04845	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KFS85_04850	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KFS85_04860	COG2895	sulfate adenylyltransferase (ATP) activity
KFS85_04860	COG0529	Catalyzes the synthesis of activated sulfate
KFS85_04865	COG0840	transmembrane signaling receptor activity
KFS85_04870	COG0438	transferase activity, transferring glycosyl groups
KFS85_04890	COG1115	amino acid carrier protein
KFS85_04915	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KFS85_04925	COG1609	Transcriptional regulator
KFS85_04940	COG0179	Fumarylacetoacetate (FAA) hydrolase
KFS85_04955	COG0471	metal ion transport
KFS85_04955	COG3273	potassium ion transport
KFS85_04965	COG2022	thiamine diphosphate biosynthetic process
KFS85_04985	COG0174	glutamine synthetase
KFS85_04990	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
KFS85_05000	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
KFS85_05015	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KFS85_05030	COG3511	phospholipase C
KFS85_05045	COG0189	ligase activity
KFS85_05055	COG0745	RESPONSE REGULATOR receiver
KFS85_05070	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
KFS85_05100	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KFS85_05140	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
KFS85_05140	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KFS85_05150	COG1262	PFAM Formylglycine-generating sulfatase enzyme
KFS85_05170	COG1174	glycine betaine transport
KFS85_05175	COG1125	glycine betaine transport
KFS85_05185	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KFS85_05190	COG0564	pseudouridine synthase activity
KFS85_05200	COG0840	transmembrane signaling receptor activity
KFS85_05205	COG4993	Dehydrogenase
KFS85_05215	COG3387	PFAM Glycoside hydrolase 15-related
KFS85_05220	COG1877	trehalose-phosphatase activity
KFS85_05240	COG0454	-acetyltransferase
KFS85_05265	COG0542	response to heat
KFS85_05290	COG0019	diaminopimelate decarboxylase activity
KFS85_05295	COG4264	IucA IucC family
KFS85_05300	COG2814	Major facilitator Superfamily
KFS85_05305	COG4264	IucA IucC family
KFS85_05315	COG4772	TonB-dependent receptor
KFS85_05325	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KFS85_05325	COG4651	solute:proton antiporter activity
KFS85_05360	COG0488	(ABC) transporter
KFS85_05435	COG0217	transcriptional regulatory protein
KFS85_05445	COG0632	four-way junction helicase activity
KFS85_05450	COG3158	transport of potassium into the cell
KFS85_05460	COG0824	Thioesterase
KFS85_05470	COG0848	biopolymer transport protein
KFS85_05485	COG2885	chlorophyll binding
KFS85_05495	COG0602	queuosine metabolic process
KFS85_05500	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KFS85_05520	COG0514	ATP-dependent DNA helicase (RecQ)
KFS85_05525	COG0783	Belongs to the Dps family
KFS85_05530	COG1643	Atp-dependent helicase
KFS85_05575	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KFS85_05600	COG1073	alpha beta
KFS85_05640	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
KFS85_05655	COG1946	Acyl-CoA thioesterase
KFS85_05660	COG1024	Enoyl-CoA hydratase
KFS85_05660	COG1250	3-hydroxyacyl-CoA dehydrogenase
KFS85_05670	COG0824	Thioesterase
KFS85_05675	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KFS85_05680	COG0261	This protein binds to 23S rRNA in the presence of protein L20
KFS85_05685	COG0211	Belongs to the bacterial ribosomal protein bL27 family
KFS85_05705	COG0728	peptidoglycan biosynthetic process
KFS85_05725	COG0196	riboflavin kinase activity
KFS85_05740	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
KFS85_05760	COG0750	zinc metalloprotease
KFS85_05770	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KFS85_05775	COG1845	cytochrome c oxidase, subunit III
KFS85_05780	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
KFS85_05790	COG0156	8-amino-7-oxononanoate synthase activity
KFS85_05800	COG3152	Membrane
KFS85_05850	COG0745	RESPONSE REGULATOR receiver
KFS85_05880	COG4794	Type iii secretion
KFS85_05905	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KFS85_05950	COG2207	Transcriptional regulator
KFS85_05975	COG0129	dihydroxy-acid dehydratase activity
KFS85_06000	COG1012	belongs to the aldehyde dehydrogenase family
KFS85_06005	COG1879	ABC-type sugar transport system periplasmic component
KFS85_06010	COG1129	ABC transporter
KFS85_06015	COG1172	Belongs to the binding-protein-dependent transport system permease family
KFS85_06020	COG1172	Belongs to the binding-protein-dependent transport system permease family
KFS85_06030	COG1082	Xylose isomerase domain protein TIM barrel
KFS85_06035	COG0625	glutathione transferase activity
KFS85_06045	COG0475	glutathione-regulated potassium exporter activity
KFS85_06065	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KFS85_06070	COG2070	2-Nitropropane dioxygenase
KFS85_06080	COG0228	four-way junction DNA binding
KFS85_06085	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KFS85_06095	COG0335	large ribosomal subunit rRNA binding
KFS85_06100	COG0534	Mate efflux family protein
KFS85_06135	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KFS85_06160	COG5444	nuclease activity
KFS85_06185	COG3209	COG3209 Rhs family protein
KFS85_06345	COG3179	chitinase
KFS85_06360	COG3179	chitinase
KFS85_06540	COG2855	membrane
KFS85_06555	COG1024	Enoyl-CoA hydratase
KFS85_06555	COG1250	3-hydroxyacyl-CoA dehydrogenase
KFS85_06570	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KFS85_06575	COG0481	GTPase activity
KFS85_06580	COG0681	Belongs to the peptidase S26 family
KFS85_06595	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KFS85_06605	COG1381	Involved in DNA repair and RecF pathway recombination
KFS85_06610	COG2204	response regulator
KFS85_06620	COG2954	triphosphatase activity
KFS85_06630	COG1472	Belongs to the glycosyl hydrolase 3 family
KFS85_06635	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
KFS85_06640	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
KFS85_06645	COG1278	Cold shock
KFS85_06660	COG1201	RNA secondary structure unwinding
KFS85_06665	COG1793	dna ligase
KFS85_06665	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
KFS85_06670	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
KFS85_06670	COG1793	dna ligase
KFS85_06700	COG0443	Heat shock 70 kDa protein
KFS85_06710	COG0183	Belongs to the thiolase family
KFS85_06740	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
KFS85_06740	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
KFS85_06740	COG1703	isobutyryl-CoA mutase activity
KFS85_06785	COG3250	beta-galactosidase activity
KFS85_06790	COG2186	Transcriptional regulator
KFS85_06800	COG0784	Response regulator, receiver
KFS85_06800	COG2205	protein histidine kinase activity
KFS85_06800	COG2198	Histidine kinase
KFS85_06825	COG1451	nucleotide metabolic process
KFS85_06835	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KFS85_06870	COG1077	Cell shape determining protein MreB Mrl
KFS85_06875	COG1047	Peptidyl-prolyl cis-trans
KFS85_06880	COG2824	Alkylphosphonate utilization operon protein PhnA
KFS85_06895	COG0583	DNA-binding transcription factor activity
KFS85_06900	COG1902	pentaerythritol trinitrate reductase activity
KFS85_06905	COG2814	Major facilitator Superfamily
KFS85_06935	COG0392	lysyltransferase activity
KFS85_06935	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KFS85_06945	COG0251	oxidation-reduction process
KFS85_06965	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KFS85_06990	COG1595	DNA-templated transcription, initiation
KFS85_07005	COG2878	Part of a membrane complex involved in electron transport
KFS85_07045	COG0346	lactoylglutathione lyase activity
KFS85_07055	COG2040	homocysteine
KFS85_07065	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
KFS85_07080	COG3118	belongs to the thioredoxin family
KFS85_07090	COG0495	leucyl-tRNA aminoacylation
KFS85_07105	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KFS85_07120	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KFS85_07135	COG2968	Membrane
KFS85_07155	COG0312	modulator of DNA gyrase
KFS85_07165	COG0312	modulator of DNA gyrase
KFS85_07180	COG4104	PAAR repeat-containing protein
KFS85_07190	COG0142	geranyltranstransferase activity
KFS85_07195	COG1722	exodeoxyribonuclease VII activity
KFS85_07210	COG1785	Belongs to the alkaline phosphatase family
KFS85_07215	COG1301	dicarboxylic acid transport
KFS85_07225	COG1607	acyl-coa hydrolase
KFS85_07230	COG0791	NLP P60 protein
KFS85_07235	COG0791	NLP P60 protein
KFS85_07240	COG1047	Peptidyl-prolyl cis-trans
KFS85_07245	COG2311	Membrane
KFS85_07250	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KFS85_07285	COG3590	peptidase
KFS85_07295	COG0457	Tetratricopeptide repeat
KFS85_07300	COG4771	TonB-dependent receptor
KFS85_07310	COG4771	TonB-dependent receptor
KFS85_07325	COG0489	protein tyrosine kinase activity
KFS85_07330	COG0717	Belongs to the dCTP deaminase family
KFS85_07335	COG1714	RDD family
KFS85_07355	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KFS85_07375	COG0494	nUDIX hydrolase
KFS85_07380	COG0433	COG0433 Predicted ATPase
KFS85_07385	COG0741	lytic transglycosylase activity
KFS85_07390	COG0688	phosphatidylethanolamine metabolic process
KFS85_07400	COG2890	protein-(glutamine-N5) methyltransferase activity
KFS85_07465	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KFS85_07495	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KFS85_07505	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KFS85_07510	COG0649	NAD binding
KFS85_07515	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
KFS85_07520	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
KFS85_07525	COG1034	ATP synthesis coupled electron transport
KFS85_07560	COG1007	ATP synthesis coupled electron transport
KFS85_07575	COG0195	Participates in both transcription termination and antitermination
KFS85_07590	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KFS85_07600	COG1185	polyribonucleotide nucleotidyltransferase activity
KFS85_07610	COG3300	MHYT domain
KFS85_07610	COG5001	Diguanylate cyclase
KFS85_07625	COG0840	transmembrane signaling receptor activity
KFS85_07630	COG0840	transmembrane signaling receptor activity
KFS85_07635	COG0835	chemotaxis
KFS85_07680	COG1194	a g-specific adenine glycosylase
KFS85_07685	COG0552	protein localization to endoplasmic reticulum
KFS85_07695	COG3938	Belongs to the proline racemase family
KFS85_07700	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KFS85_07715	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KFS85_07725	COG0006	proline dipeptidase activity
KFS85_07740	COG0531	amino acid
KFS85_07765	COG4206	TonB-dependent receptor
KFS85_07775	COG3507	Belongs to the glycosyl hydrolase 43 family
KFS85_07785	COG4771	TonB-dependent receptor
KFS85_07815	COG0742	ribosomal rna small subunit methyltransferase
KFS85_07830	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
KFS85_07835	COG0405	Gamma-glutamyltransferase
KFS85_07855	COG0644	oxidoreductase
KFS85_07885	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KFS85_07890	COG3291	Pkd domain containing protein
KFS85_07895	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KFS85_07900	COG0657	acetylesterase activity
KFS85_07900	COG2755	lipolytic protein G-D-S-L family
KFS85_07905	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KFS85_07915	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KFS85_07925	COG1862	Preprotein translocase
KFS85_07960	COG1509	lysine 2,3-aminomutase activity
KFS85_07970	COG3548	integral membrane protein
KFS85_07975	COG0402	S-adenosylhomocysteine deaminase activity
KFS85_08000	COG5434	Belongs to the glycosyl hydrolase 28 family
KFS85_08005	COG4677	pectinesterase activity
KFS85_08015	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
KFS85_08100	COG2814	Major facilitator Superfamily
KFS85_08105	COG2166	iron-sulfur cluster assembly
KFS85_08120	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KFS85_08125	COG0137	argininosuccinate synthase activity
KFS85_08130	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KFS85_08135	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
KFS85_08150	COG0165	Argininosuccinate lyase
KFS85_08170	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KFS85_08195	COG1294	oxidase, subunit
KFS85_08205	COG4988	ABC transporter
KFS85_08210	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KFS85_08215	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KFS85_08265	COG4133	protoheme IX ABC transporter activity
KFS85_08270	COG0436	Aminotransferase
KFS85_08300	COG1187	pseudouridine synthase activity
KFS85_08310	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KFS85_08315	COG2350	Protein conserved in bacteria
KFS85_08350	COG0395	ABC-type sugar transport system, permease component
KFS85_08365	COG0129	dihydroxy-acid dehydratase activity
KFS85_08380	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KFS85_08385	COG3842	ATPase activity
KFS85_08390	COG0354	folic acid binding
KFS85_08400	COG2009	succinate dehydrogenase
KFS85_08405	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
KFS85_08420	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
KFS85_08430	COG4591	ABC-type transport system involved in lipoprotein release permease component
KFS85_08460	COG0811	peptide transport
KFS85_08465	COG0848	biopolymer transport protein
KFS85_08470	COG1132	(ABC) transporter
KFS85_08475	COG1663	tetraacyldisaccharide 4'-kinase activity
KFS85_08485	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KFS85_08500	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KFS85_08530	COG0348	domain, Protein
KFS85_08540	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KFS85_08550	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
KFS85_08555	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KFS85_08565	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KFS85_08590	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KFS85_08610	COG0704	Plays a role in the regulation of phosphate uptake
KFS85_08620	COG0581	inorganic phosphate transmembrane transporter activity
KFS85_08625	COG0573	inorganic phosphate transmembrane transporter activity
KFS85_08630	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KFS85_08635	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KFS85_08655	COG0659	secondary active sulfate transmembrane transporter activity
KFS85_08660	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KFS85_08670	COG1024	Enoyl-CoA hydratase
KFS85_08725	COG5002	protein histidine kinase activity
KFS85_08725	COG0784	Response regulator, receiver
KFS85_08725	COG2205	protein histidine kinase activity
KFS85_08730	COG2733	membrane
KFS85_08750	COG0686	Belongs to the AlaDH PNT family
KFS85_08755	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KFS85_08760	COG1396	sequence-specific DNA binding
KFS85_08760	COG1917	Cupin 2, conserved barrel domain protein
KFS85_08765	COG1012	belongs to the aldehyde dehydrogenase family
KFS85_08775	COG2223	nitrite transmembrane transporter activity
KFS85_08785	COG0243	molybdopterin cofactor binding
KFS85_08800	COG0477	Major facilitator Superfamily
KFS85_08805	COG3706	GGDEF domain
KFS85_08810	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KFS85_08815	COG0174	glutamine synthetase
KFS85_08820	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
KFS85_08825	COG0174	glutamine synthetase
KFS85_08840	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
KFS85_08860	COG3842	ATPase activity
KFS85_08865	COG1176	ABC-type spermidine putrescine transport system, permease component I
KFS85_08870	COG1177	transmembrane transport
KFS85_08875	COG1012	belongs to the aldehyde dehydrogenase family
KFS85_08890	COG4535	Mg2 and Co2 transporter CorC
KFS85_08905	COG1702	phosphate starvation-inducible protein PhoH
KFS85_08920	COG0741	lytic transglycosylase activity
KFS85_08925	COG0723	plastoquinol--plastocyanin reductase activity
KFS85_08930	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KFS85_08940	COG2857	Cytochrome c1
KFS85_08945	COG0625	glutathione transferase activity
KFS85_08950	COG2969	positive regulation of protein catabolic process
KFS85_08990	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
KFS85_08995	COG1028	Short-chain dehydrogenase reductase Sdr
KFS85_09000	COG2095	MarC family integral membrane protein
KFS85_09010	COG1611	Belongs to the LOG family
KFS85_09015	COG3275	phosphorelay sensor kinase activity
KFS85_09060	COG0556	nucleotide-excision repair
KFS85_09075	COG3706	GGDEF domain
KFS85_09110	COG0840	transmembrane signaling receptor activity
KFS85_09120	COG0840	transmembrane signaling receptor activity
KFS85_09130	COG0835	chemotaxis
KFS85_09140	COG0840	transmembrane signaling receptor activity
KFS85_09150	COG0840	transmembrane signaling receptor activity
KFS85_09155	COG0840	transmembrane signaling receptor activity
KFS85_09165	COG0840	transmembrane signaling receptor activity
KFS85_09175	COG0840	transmembrane signaling receptor activity
KFS85_09180	COG0840	transmembrane signaling receptor activity
KFS85_09185	COG0840	transmembrane signaling receptor activity
KFS85_09190	COG0840	transmembrane signaling receptor activity
KFS85_09205	COG0745	RESPONSE REGULATOR receiver
KFS85_09220	COG1192	Involved in chromosome partitioning
KFS85_09230	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KFS85_09235	COG0784	Response regulator, receiver
KFS85_09235	COG2198	Histidine kinase
KFS85_09235	COG0643	Histidine kinase
KFS85_09285	COG1684	flagellar biosynthetic protein fliR
KFS85_09290	COG1987	bacterial-type flagellum assembly
KFS85_09300	COG3190	flagellar
KFS85_09350	COG1677	Flagellar hook-basal body complex protein FliE
KFS85_09405	COG1028	Short-chain dehydrogenase reductase Sdr
KFS85_09415	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KFS85_09435	COG2201	protein-glutamate methylesterase activity
KFS85_09440	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
KFS85_09445	COG2197	response regulator
KFS85_09465	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
KFS85_09470	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KFS85_09475	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KFS85_09480	COG1256	bacterial-type flagellum assembly
KFS85_09480	COG4786	Flagellar basal body rod
KFS85_09490	COG1706	bacterial-type flagellum-dependent cell motility
KFS85_09495	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
KFS85_09510	COG1749	Flagellar hook protein flgE
KFS85_09520	COG1558	bacterial-type flagellum-dependent cell motility
KFS85_09530	COG0835	chemotaxis
KFS85_09530	COG0784	Response regulator, receiver
KFS85_09575	COG1116	anion transmembrane transporter activity
KFS85_09590	COG2915	High frequency lysogenization protein hflD homolog
KFS85_09595	COG0482	sulfurtransferase activity
KFS85_09615	COG0542	response to heat
KFS85_09625	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
KFS85_09635	COG0492	ferredoxin-NADP+ reductase activity
KFS85_09640	COG1674	ftsk spoiiie
KFS85_09670	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KFS85_09675	COG0038	chloride channel
KFS85_09710	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KFS85_09745	COG1595	DNA-templated transcription, initiation
KFS85_09765	COG3038	cytochrome b561
KFS85_09795	COG2244	polysaccharide biosynthetic process
KFS85_09835	COG0438	transferase activity, transferring glycosyl groups
KFS85_09840	COG0438	transferase activity, transferring glycosyl groups
KFS85_09860	COG1132	(ABC) transporter
KFS85_09875	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KFS85_09880	COG1304	FMN binding
KFS85_09890	COG0346	lactoylglutathione lyase activity
KFS85_09940	COG1024	Enoyl-CoA hydratase
KFS85_09945	COG1024	Enoyl-CoA hydratase
KFS85_09955	COG1024	Enoyl-CoA hydratase
KFS85_09970	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
KFS85_09975	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
KFS85_10130	COG1649	PFAM Uncharacterised BCR, COG1649
KFS85_10165	COG5000	phosphorelay sensor kinase activity
KFS85_10165	COG5002	protein histidine kinase activity
KFS85_10185	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KFS85_10225	COG2205	protein histidine kinase activity
KFS85_10225	COG0784	Response regulator, receiver
KFS85_10230	COG2183	response to ionizing radiation
KFS85_10235	COG0784	Response regulator, receiver
KFS85_10235	COG4191	Histidine kinase
KFS85_10245	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KFS85_10245	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
KFS85_10265	COG3243	poly(R)-hydroxyalkanoic acid synthase
KFS85_10275	COG1183	phosphatidylcholine synthase activity
KFS85_10280	COG1028	Short-chain dehydrogenase reductase Sdr
KFS85_10295	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
KFS85_10305	COG0668	transmembrane transport
KFS85_10310	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
KFS85_10325	COG1914	H( )-stimulated, divalent metal cation uptake system
KFS85_10335	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
KFS85_10340	COG1501	Belongs to the glycosyl hydrolase 31 family
KFS85_10355	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KFS85_10370	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KFS85_10370	COG0475	glutathione-regulated potassium exporter activity
KFS85_10375	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KFS85_10385	COG0746	molybdenum cofactor guanylyltransferase activity
KFS85_10395	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KFS85_10405	COG1426	Protein conserved in bacteria
KFS85_10415	COG0820	rRNA (adenine-C2-)-methyltransferase activity
KFS85_10430	COG1024	Enoyl-CoA hydratase
KFS85_10430	COG1250	3-hydroxyacyl-CoA dehydrogenase
KFS85_10435	COG0183	Belongs to the thiolase family
KFS85_10440	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KFS85_10450	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KFS85_10455	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
KFS85_10465	COG0776	regulation of translation
KFS85_10470	COG0539	negative regulation of cytoplasmic translation
KFS85_10475	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
KFS85_10480	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KFS85_10490	COG2957	Belongs to the agmatine deiminase family
KFS85_10495	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KFS85_10535	COG0316	Belongs to the HesB IscA family
KFS85_10535	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
KFS85_10550	COG0428	transporter
KFS85_10565	COG1530	ribonuclease E activity
KFS85_10615	COG0077	Prephenate dehydratase
KFS85_10615	COG1605	Chorismate mutase
KFS85_10620	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KFS85_10625	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KFS85_10665	COG4221	oxidoreductase activity
KFS85_10680	COG1228	amidohydrolase
KFS85_10700	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
KFS85_10715	COG1309	transcriptional regulator
KFS85_10740	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
KFS85_10750	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
KFS85_10755	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KFS85_10790	COG2977	Belongs to the P-Pant transferase superfamily
KFS85_10795	COG0316	Belongs to the HesB IscA family
KFS85_10820	COG2197	response regulator
KFS85_10865	COG0288	reversible hydration of carbon dioxide
KFS85_10870	COG0662	Cupin 2, conserved barrel domain protein
KFS85_10880	COG3844	kynureninase activity
KFS85_10890	COG2925	Exonuclease
KFS85_10925	COG2902	Dehydrogenase
KFS85_10935	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KFS85_10940	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KFS85_10945	COG1960	acyl-CoA dehydrogenase activity
KFS85_10950	COG2226	methyltransferase
KFS85_10955	COG0646	methionine synthase
KFS85_10955	COG1410	methionine synthase
KFS85_10960	COG0646	methionine synthase
KFS85_10960	COG1410	methionine synthase
KFS85_10980	COG2900	Belongs to the SlyX family
KFS85_10995	COG0386	Belongs to the glutathione peroxidase family
KFS85_11005	COG1725	Transcriptional regulator
KFS85_11010	COG1131	(ABC) transporter
KFS85_11050	COG2850	peptidyl-arginine hydroxylation
KFS85_11105	COG1132	(ABC) transporter
KFS85_11120	COG0287	Prephenate dehydrogenase
KFS85_11120	COG1605	Chorismate mutase
KFS85_11125	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
KFS85_11130	COG0484	heat shock protein binding
KFS85_11135	COG0443	Heat shock 70 kDa protein
KFS85_11140	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KFS85_11145	COG1420	regulation of RNA biosynthetic process
KFS85_11150	COG0497	DNA recombination
KFS85_11155	COG0735	belongs to the Fur family
KFS85_11160	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KFS85_11170	COG2867	negative regulation of translational initiation
KFS85_11175	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
KFS85_11180	COG1404	Belongs to the peptidase S8 family
KFS85_11215	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KFS85_11230	COG0583	DNA-binding transcription factor activity
KFS85_11245	COG0415	Belongs to the DNA photolyase family
KFS85_11250	COG0305	Participates in initiation and elongation during chromosome replication
KFS85_11260	COG1960	acyl-CoA dehydrogenase activity
KFS85_11275	COG0084	hydrolase, TatD family'
KFS85_11280	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KFS85_11320	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KFS85_11345	COG0386	Belongs to the glutathione peroxidase family
KFS85_11355	COG0339	signal peptide processing
KFS85_11360	COG1846	Transcriptional regulator
KFS85_11400	COG1472	Belongs to the glycosyl hydrolase 3 family
KFS85_11410	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KFS85_11425	COG0488	(ABC) transporter
KFS85_11430	COG0513	Belongs to the DEAD box helicase family
KFS85_11460	COG0657	acetylesterase activity
KFS85_11465	COG0625	glutathione transferase activity
KFS85_11475	COG0564	pseudouridine synthase activity
KFS85_11480	COG4681	YaeQ
KFS85_11485	COG2081	HI0933 family
KFS85_11515	COG1028	Short-chain dehydrogenase reductase Sdr
KFS85_11535	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KFS85_11540	COG0860	N-Acetylmuramoyl-L-alanine amidase
KFS85_11545	COG0802	atpase or kinase
KFS85_11550	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KFS85_11550	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
KFS85_11555	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KFS85_11600	COG1960	acyl-CoA dehydrogenase activity
KFS85_11610	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KFS85_11630	COG0438	transferase activity, transferring glycosyl groups
KFS85_11640	COG0438	transferase activity, transferring glycosyl groups
KFS85_11645	COG0438	transferase activity, transferring glycosyl groups
KFS85_11695	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KFS85_11700	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KFS85_11710	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KFS85_11770	COG0318	PFAM AMP-dependent synthetase and ligase
KFS85_11775	COG1024	Enoyl-CoA hydratase
KFS85_11780	COG2198	Histidine kinase
KFS85_11780	COG0784	Response regulator, receiver
KFS85_11780	COG2205	protein histidine kinase activity
KFS85_11790	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
KFS85_11805	COG4676	Protein conserved in bacteria
KFS85_11820	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KFS85_11825	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
KFS85_11835	COG0505	Belongs to the CarA family
KFS85_11845	COG2258	MOSC domain
KFS85_11850	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KFS85_11870	COG1024	Enoyl-CoA hydratase
KFS85_11890	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KFS85_11910	COG0277	FAD linked oxidase domain protein
KFS85_11915	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KFS85_11930	COG0531	amino acid
KFS85_11935	COG0531	amino acid
KFS85_11940	COG0235	Class ii aldolase
KFS85_11945	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
KFS85_11950	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
KFS85_11965	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KFS85_11965	COG0140	phosphoribosyl-ATP diphosphatase activity
KFS85_11980	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KFS85_11990	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KFS85_11995	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KFS85_12000	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
KFS85_12010	COG0124	histidyl-tRNA synthetase
KFS85_12015	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KFS85_12025	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KFS85_12035	COG2951	lytic endotransglycosylase activity
KFS85_12045	COG0527	aspartate kinase activity
KFS85_12045	COG0460	homoserine dehydrogenase
KFS85_12060	COG1012	belongs to the aldehyde dehydrogenase family
KFS85_12075	COG0167	dihydroorotate dehydrogenase activity
KFS85_12080	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KFS85_12090	COG0210	DNA helicase
KFS85_12095	COG0671	phosphoesterase, PA-phosphatase related
KFS85_12110	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
KFS85_12180	COG1262	PFAM Formylglycine-generating sulfatase enzyme
KFS85_12210	COG1262	PFAM Formylglycine-generating sulfatase enzyme
KFS85_12275	COG0166	Belongs to the GPI family
KFS85_12290	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
KFS85_12300	COG0617	tRNA 3'-terminal CCA addition
KFS85_12320	COG0860	N-Acetylmuramoyl-L-alanine amidase
KFS85_12325	COG0477	Major facilitator Superfamily
KFS85_12330	COG2115	Belongs to the xylose isomerase family
KFS85_12335	COG1070	Carbohydrate kinase
KFS85_12345	COG1501	Belongs to the glycosyl hydrolase 31 family
KFS85_12370	COG0800	Aldolase
KFS85_12385	COG3734	2-keto-3-deoxy-galactonokinase
KFS85_12390	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
KFS85_12400	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KFS85_12410	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KFS85_12415	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
KFS85_12430	COG0351	phosphomethylpyrimidine kinase
KFS85_12430	COG0352	thiamine-phosphate diphosphorylase activity
KFS85_12455	COG0583	DNA-binding transcription factor activity
KFS85_12460	COG1741	Belongs to the pirin family
KFS85_12500	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KFS85_12505	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KFS85_12510	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
KFS85_12515	COG1546	Belongs to the CinA family
KFS85_12520	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KFS85_12530	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KFS85_12535	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KFS85_12540	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KFS85_12545	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
KFS85_12550	COG1534	Rna-binding protein
KFS85_12565	COG1238	metal cluster binding
KFS85_12575	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
KFS85_12590	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
KFS85_12595	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
KFS85_12600	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
KFS85_12610	COG2877	3-deoxy-8-phosphooctulonate synthase activity
KFS85_12615	COG0504	CTP synthase activity
KFS85_12640	COG1253	flavin adenine dinucleotide binding
KFS85_12655	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KFS85_12695	COG0069	glutamate synthase activity
KFS85_12700	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
KFS85_12715	COG1609	Transcriptional regulator
KFS85_12720	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
KFS85_12720	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KFS85_12725	COG1105	Belongs to the carbohydrate kinase PfkB family
KFS85_12730	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KFS85_12730	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KFS85_12760	COG0577	efflux transmembrane transporter activity
KFS85_12760	COG1136	(ABC) transporter
KFS85_12800	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KFS85_12810	COG0557	exoribonuclease II activity
KFS85_12845	COG2814	Major facilitator Superfamily
KFS85_12850	COG1566	PFAM secretion protein HlyD family protein
KFS85_12890	COG0367	asparagine synthase
KFS85_12900	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KFS85_12905	COG1393	Belongs to the ArsC family
KFS85_12920	COG0024	Methionine aminopeptidase
KFS85_12960	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KFS85_12970	COG0528	UMP kinase activity
KFS85_12980	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KFS85_12985	COG0575	Belongs to the CDS family
KFS85_12990	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
KFS85_12995	COG0750	zinc metalloprotease
KFS85_13005	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KFS85_13015	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KFS85_13020	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KFS85_13035	COG0825	malonyl-CoA metabolic process
KFS85_13045	COG1981	membrane
KFS85_13115	COG1132	(ABC) transporter
KFS85_13140	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KFS85_13165	COG1187	pseudouridine synthase activity
KFS85_13310	COG0735	belongs to the Fur family
KFS85_13340	COG4452	Inner membrane protein CreD
KFS85_13355	COG2205	protein histidine kinase activity
KFS85_13365	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
KFS85_13385	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KFS85_13395	COG0643	Histidine kinase
KFS85_13395	COG2198	Histidine kinase
KFS85_13405	COG0840	transmembrane signaling receptor activity
KFS85_13410	COG0840	transmembrane signaling receptor activity
KFS85_13415	COG0835	chemotaxis
KFS85_13420	COG2203	Gaf domain
KFS85_13420	COG5001	Diguanylate cyclase
KFS85_13420	COG4251	negative regulation of phosphorylation
KFS85_13420	COG3706	GGDEF domain
KFS85_13445	COG2211	Major facilitator Superfamily
KFS85_13470	COG1515	deoxyribonuclease V activity
KFS85_13495	COG1966	Carbon starvation protein
KFS85_13500	COG2879	small protein
KFS85_13505	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KFS85_13525	COG0823	Involved in the tonB-independent uptake of proteins
KFS85_13525	COG1506	peptidase
KFS85_13530	COG1297	OPT oligopeptide transporter protein
KFS85_13535	COG3104	oligopeptide transport
KFS85_13555	COG3550	peptidyl-serine autophosphorylation
KFS85_13560	COG0629	single-stranded DNA binding
KFS85_13565	COG0142	geranyltranstransferase activity
KFS85_13590	COG0527	aspartate kinase activity
KFS85_13595	COG0384	phenazine biosynthesis protein PhzF
KFS85_13605	COG1764	response to oxidative stress
KFS85_13620	COG0739	heme binding
KFS85_13635	COG0693	protein deglycase activity
KFS85_13650	COG0719	Fe-S assembly protein
KFS85_13655	COG0396	ATPase activity
KFS85_13660	COG0719	Fe-S assembly protein
KFS85_13665	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KFS85_13675	COG2146	nitrite reductase [NAD(P)H] activity
KFS85_13680	COG4774	siderophore transport
KFS85_13705	COG1477	protein flavinylation
KFS85_13710	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KFS85_13735	COG1555	photosystem II stabilization
KFS85_13750	COG3178	'Phosphotransferase
KFS85_13755	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KFS85_13765	COG0628	permease
KFS85_13790	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KFS85_13840	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
KFS85_13855	COG1137	ATPase activity
KFS85_13870	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KFS85_13880	COG1660	Displays ATPase and GTPase activities
KFS85_13890	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KFS85_13895	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KFS85_13900	COG2239	Acts as a magnesium transporter
KFS85_13920	COG1113	amino acid transport
KFS85_13930	COG0840	transmembrane signaling receptor activity
KFS85_13950	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KFS85_13965	COG0519	Catalyzes the synthesis of GMP from XMP
KFS85_14050	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KFS85_14060	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KFS85_14065	COG2814	Major facilitator Superfamily
KFS85_14085	COG3038	cytochrome b561
KFS85_14100	COG1760	l-serine dehydratase
KFS85_14110	COG0596	Alpha beta hydrolase
KFS85_14110	COG0508	dehydrogenase complex catalyzes the overall conversion of
KFS85_14115	COG0460	homoserine dehydrogenase
KFS85_14115	COG0527	aspartate kinase activity
KFS85_14120	COG0626	cystathionine gamma-synthase activity
KFS85_14125	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KFS85_14130	COG0739	heme binding
KFS85_14135	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KFS85_14140	COG1272	protein, Hemolysin III
KFS85_14145	COG2982	Protein involved in outer membrane biogenesis
KFS85_14150	COG0517	IMP dehydrogenase activity
KFS85_14155	COG0463	Glycosyl transferase, family 2
KFS85_14160	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KFS85_14165	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KFS85_14200	COG1960	acyl-CoA dehydrogenase activity
KFS85_14205	COG1304	FMN binding
KFS85_14215	COG1657	PFAM Prenyltransferase squalene oxidase
KFS85_14220	COG0142	geranyltranstransferase activity
KFS85_14225	COG2124	cytochrome p450
KFS85_14230	COG1028	Short-chain dehydrogenase reductase Sdr
KFS85_14235	COG1141	Ferredoxin
KFS85_14240	COG2124	cytochrome p450
KFS85_14245	COG2124	cytochrome p450
KFS85_14275	COG0697	spore germination
KFS85_14315	COG0330	HflC and HflK could
KFS85_14320	COG1742	UPF0060 membrane protein
KFS85_14325	COG3956	TIGRFAM MazG family protein
KFS85_14330	COG1218	3'(2'),5'-bisphosphate nucleotidase
KFS85_14335	COG0494	nUDIX hydrolase
KFS85_14345	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KFS85_14355	COG0837	glucose binding
KFS85_14370	COG3858	chitin binding
KFS85_14370	COG1388	LysM domain
KFS85_14375	COG3525	Glycosyl hydrolase, family 20, catalytic domain
KFS85_14385	COG1472	Belongs to the glycosyl hydrolase 3 family
KFS85_14400	COG1472	Belongs to the glycosyl hydrolase 3 family
KFS85_14410	COG3537	Alpha-1,2-mannosidase
KFS85_14545	COG3142	Participates in the control of copper homeostasis
KFS85_14550	COG1446	asparaginase
KFS85_14570	COG2201	protein-glutamate methylesterase activity
KFS85_14575	COG2198	Histidine kinase
KFS85_14575	COG0784	Response regulator, receiver
KFS85_14575	COG0643	Histidine kinase
KFS85_14580	COG0840	transmembrane signaling receptor activity
KFS85_14585	COG0835	chemotaxis
KFS85_14600	COG0189	ligase activity
KFS85_14620	COG1199	ATP-dependent helicase activity
KFS85_14630	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KFS85_14635	COG1216	Glycosyl transferase, family 2
KFS85_14645	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KFS85_14670	COG4585	Histidine kinase
KFS85_14680	COG0850	regulation of cytokinetic process
KFS85_14685	COG2894	cell division
KFS85_14690	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
KFS85_14705	COG2205	protein histidine kinase activity
KFS85_14710	COG0745	RESPONSE REGULATOR receiver
KFS85_14720	COG2194	sulfuric ester hydrolase activity
KFS85_14740	COG2814	Major facilitator Superfamily
KFS85_14765	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KFS85_14765	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KFS85_14770	COG2203	Gaf domain
KFS85_14770	COG3706	GGDEF domain
KFS85_14770	COG4251	negative regulation of phosphorylation
KFS85_14770	COG5001	Diguanylate cyclase
KFS85_14780	COG0753	catalase activity
KFS85_14805	COG1063	alcohol dehydrogenase
KFS85_14815	COG3459	Glycosyltransferase 36 associated
KFS85_14835	COG0492	ferredoxin-NADP+ reductase activity
KFS85_14890	COG1401	restriction endodeoxyribonuclease activity
KFS85_14940	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KFS85_14950	COG0330	HflC and HflK could
KFS85_14955	COG0330	HflC and HflK could
KFS85_14960	COG0604	alcohol dehydrogenase
KFS85_14980	COG0678	peroxiredoxin activity
KFS85_14990	COG4953	penicillin-binding protein 1C
KFS85_15020	COG2373	Large extracellular alpha-helical protein
KFS85_15065	COG0372	Belongs to the citrate synthase family
KFS85_15070	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KFS85_15085	COG0587	DNA-directed DNA polymerase activity
KFS85_15115	COG2161	toxin-antitoxin pair type II binding
KFS85_15120	COG4115	mRNA cleavage
KFS85_15135	COG3549	Plasmid maintenance system killer
KFS85_15180	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KFS85_15185	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KFS85_15190	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KFS85_15200	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KFS85_15205	COG1028	Short-chain dehydrogenase reductase Sdr
KFS85_15210	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KFS85_15215	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KFS85_15220	COG0333	Belongs to the bacterial ribosomal protein bL32 family
KFS85_15225	COG1399	metal-binding, possibly nucleic acid-binding protein
KFS85_15250	COG0714	Associated with various cellular activities
KFS85_15270	COG0537	adenosine 5'-monophosphoramidase activity
KFS85_15390	COG0314	molybdopterin synthase activity
KFS85_15395	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
KFS85_15400	COG0315	cyclic pyranopterin monophosphate synthase activity
KFS85_15410	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KFS85_15415	COG1234	tRNA 3'-trailer cleavage
KFS85_15425	COG0859	PFAM glycosyl transferase family 9
KFS85_15445	COG0631	protein serine/threonine phosphatase activity
KFS85_15450	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KFS85_15455	COG0328	RNA-DNA hybrid ribonuclease activity
KFS85_15465	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KFS85_15470	COG3942	CHAP domain
KFS85_15470	COG1388	LysM domain
KFS85_15505	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KFS85_15515	COG0544	peptidyl-prolyl cis-trans isomerase activity
KFS85_15555	COG0473	3-isopropylmalate dehydrogenase activity
KFS85_15570	COG4783	chaperone-mediated protein folding
KFS85_15585	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KFS85_15590	COG0248	Ppx GppA phosphatase
KFS85_15600	COG0438	transferase activity, transferring glycosyl groups
KFS85_15610	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KFS85_15620	COG2833	Protein of unknown function (DUF455)
KFS85_15640	COG0285	dihydrofolate synthase activity
KFS85_15645	COG0588	phosphoglycerate mutase activity
KFS85_15665	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
KFS85_15670	COG4208	sulfate ABC transporter
KFS85_15675	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
KFS85_15680	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
KFS85_15685	COG0156	8-amino-7-oxononanoate synthase activity
KFS85_15700	COG2885	chlorophyll binding
KFS85_15710	COG2814	Major facilitator Superfamily
KFS85_15720	COG0667	Aldo Keto reductase
KFS85_15725	COG0604	alcohol dehydrogenase
KFS85_15730	COG1902	pentaerythritol trinitrate reductase activity
KFS85_15730	COG0446	pyridine nucleotide-disulphide oxidoreductase
KFS85_15775	COG0625	glutathione transferase activity
KFS85_15795	COG0039	L-malate dehydrogenase activity
KFS85_15805	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KFS85_15810	COG1217	gtp-binding protein TYPA
KFS85_15830	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
KFS85_15840	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
KFS85_15845	COG0203	ribosomal protein L17
KFS85_15870	COG0201	protein transport
KFS85_15880	COG1841	ribosomal large subunit assembly
KFS85_15910	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KFS85_15915	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KFS85_15925	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KFS85_15930	COG0255	Belongs to the universal ribosomal protein uL29 family
KFS85_15940	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KFS85_15955	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KFS85_15960	COG0089	rRNA binding
KFS85_15965	COG0088	Forms part of the polypeptide exit tunnel
KFS85_15975	COG0051	transcription antitermination factor activity, RNA binding
KFS85_15980	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KFS85_15985	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KFS85_16000	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KFS85_16010	COG0222	ribosome binding
KFS85_16025	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KFS85_16030	COG0250	Participates in transcription elongation, termination and antitermination
KFS85_16035	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KFS85_16045	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KFS85_16065	COG0012	GTP binding
KFS85_16070	COG0193	aminoacyl-tRNA hydrolase activity
KFS85_16080	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KFS85_16105	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
KFS85_16110	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KFS85_16120	COG5297	Belongs to the glycosyl hydrolase family 6
KFS85_16125	COG0521	Mo-molybdopterin cofactor biosynthetic process
KFS85_16145	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KFS85_16150	COG1295	ribonuclease BN
KFS85_16170	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KFS85_16175	COG1404	Belongs to the peptidase S8 family
KFS85_16180	COG1404	Belongs to the peptidase S8 family
KFS85_16185	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KFS85_16230	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
KFS85_16255	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KFS85_16255	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KFS85_16300	COG3634	alkyl hydroperoxide reductase activity
KFS85_16305	COG0583	DNA-binding transcription factor activity
KFS85_16315	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KFS85_16325	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KFS85_16335	COG2197	response regulator
KFS85_16360	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KFS85_16365	COG0697	spore germination
KFS85_16390	COG0673	inositol 2-dehydrogenase activity
KFS85_16405	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KFS85_16410	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KFS85_16420	COG2096	Adenosyltransferase
KFS85_16430	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
KFS85_16435	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KFS85_16440	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
KFS85_16445	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KFS85_16450	COG2967	ApaG domain
KFS85_16455	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KFS85_16490	COG1704	LemA family
KFS85_16495	COG0861	Integral membrane protein TerC family
KFS85_16500	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KFS85_16510	COG0642	Histidine kinase
KFS85_16525	COG4181	ATPase activity
KFS85_16530	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
KFS85_16565	COG0667	Aldo Keto reductase
KFS85_16570	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KFS85_16590	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KFS85_16620	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KFS85_16690	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KFS85_16700	COG0494	nUDIX hydrolase
KFS85_16725	COG0739	heme binding
KFS85_16735	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
KFS85_16740	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KFS85_16750	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KFS85_16755	COG1181	Belongs to the D-alanine--D-alanine ligase family
KFS85_16780	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KFS85_16795	COG3116	cell division
KFS85_16800	COG0275	rRNA processing
KFS85_16805	COG2001	Belongs to the MraZ family
KFS85_16835	COG0792	nuclease activity
KFS85_16840	COG1988	membrane-bound metal-dependent
KFS85_16845	COG0277	FAD linked oxidase domain protein
KFS85_16850	COG0745	RESPONSE REGULATOR receiver
KFS85_16855	COG2205	protein histidine kinase activity
KFS85_16865	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
KFS85_16870	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
KFS85_16895	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
KFS85_16900	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KFS85_16905	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
KFS85_16920	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KFS85_16920	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KFS85_16930	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KFS85_16970	COG0477	Major facilitator Superfamily
KFS85_16975	COG0488	(ABC) transporter
KFS85_16980	COG0242	peptide deformylase activity
KFS85_16990	COG1960	acyl-CoA dehydrogenase activity
KFS85_17010	COG1696	Membrane protein involved in D-alanine export
KFS85_17030	COG1215	transferase activity, transferring glycosyl groups
KFS85_17040	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KFS85_17090	COG2188	Transcriptional regulator
KFS85_17100	COG1450	Type ii and iii secretion system protein
KFS85_17115	COG3166	PFAM Fimbrial assembly family protein
KFS85_17120	COG3156	type II secretion system protein K
KFS85_17125	COG4795	General secretion pathway protein
KFS85_17130	COG2165	general secretion pathway protein
KFS85_17135	COG4970	Tfp pilus assembly protein FimT
KFS85_17140	COG2165	general secretion pathway protein
KFS85_17145	COG1459	type II secretion system
KFS85_17150	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KFS85_17155	COG1404	Belongs to the peptidase S8 family
KFS85_17160	COG5295	Hep Hag repeat protein
KFS85_17165	COG0047	phosphoribosylformylglycinamidine synthase activity
KFS85_17165	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KFS85_17170	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KFS85_17175	COG4974	Belongs to the 'phage' integrase family
KFS85_17200	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KFS85_17210	COG0525	valine-tRNA ligase activity
KFS85_17235	COG1183	phosphatidylcholine synthase activity
KFS85_17245	COG0442	prolyl-tRNA aminoacylation
KFS85_17260	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
KFS85_17265	COG1127	ABC transporter
KFS85_17270	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
KFS85_17270	COG3218	ABC-type transport auxiliary lipoprotein component
KFS85_17300	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KFS85_17305	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KFS85_17310	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
KFS85_17310	COG0662	Cupin 2, conserved barrel domain protein
KFS85_17335	COG2086	electron transfer activity
KFS85_17350	COG0546	phosphoglycolate phosphatase activity
KFS85_17350	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
KFS85_17355	COG0277	FAD linked oxidase domain protein
KFS85_17360	COG0300	oxidoreductase activity
KFS85_17390	COG0493	'glutamate synthase
KFS85_17430	COG1216	Glycosyl transferase, family 2
KFS85_17430	COG0438	transferase activity, transferring glycosyl groups
KFS85_17435	COG1216	Glycosyl transferase, family 2
KFS85_17435	COG0438	transferase activity, transferring glycosyl groups
KFS85_17440	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KFS85_17455	COG0626	cystathionine gamma-synthase activity
KFS85_17485	COG0625	glutathione transferase activity
KFS85_17500	COG0720	synthase
KFS85_17510	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
KFS85_17515	COG1956	GAF domain-containing protein
KFS85_17525	COG4206	TonB-dependent receptor
KFS85_17530	COG0546	phosphoglycolate phosphatase activity
KFS85_17555	COG0339	signal peptide processing
KFS85_17560	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KFS85_17570	COG2217	Heavy metal translocating P-type atpase
KFS85_17585	COG2132	Multicopper oxidase
KFS85_17605	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KFS85_17615	COG1136	(ABC) transporter
KFS85_17635	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KFS85_17650	COG0355	proton-transporting ATP synthase activity, rotational mechanism
KFS85_17665	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KFS85_17675	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KFS85_17685	COG0356	it plays a direct role in the translocation of protons across the membrane
KFS85_17700	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KFS85_17705	COG0508	dehydrogenase complex catalyzes the overall conversion of
KFS85_17740	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KFS85_17745	COG0697	spore germination
KFS85_17750	COG1666	GTP binding
KFS85_17760	COG1187	pseudouridine synthase activity
KFS85_17765	COG2813	Specifically methylates the guanine in position
KFS85_17785	COG2205	protein histidine kinase activity
KFS85_17785	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KFS85_17815	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KFS85_17890	COG0842	Transport permease protein
KFS85_17895	COG1131	(ABC) transporter
KFS85_17900	COG0025	NhaP-type Na H and K H
KFS85_17910	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
KFS85_17915	COG1573	uracil-dna glycosylase
KFS85_17925	COG3384	dioxygenase
KFS85_17950	COG0667	Aldo Keto reductase
KFS85_17965	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KFS85_18005	COG5001	Diguanylate cyclase
KFS85_18035	COG4106	trans-aconitate 2-methyltransferase activity
KFS85_18045	COG2076	Multidrug Resistance protein
KFS85_18055	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KFS85_18095	COG0531	amino acid
KFS85_18110	COG0612	Peptidase, M16
KFS85_18120	COG0741	lytic transglycosylase activity
KFS85_18135	COG2207	Transcriptional regulator
KFS85_18145	COG0598	Magnesium transport protein CorA
KFS85_18150	COG1113	amino acid transport
KFS85_18160	COG0697	spore germination
KFS85_18170	COG0583	DNA-binding transcription factor activity
KFS85_18300	COG0232	Belongs to the dGTPase family. Type 2 subfamily
KFS85_18310	COG0840	transmembrane signaling receptor activity
KFS85_18345	COG2353	YceI-like domain
KFS85_18370	COG0584	glycerophosphoryl diester phosphodiesterase
KFS85_18390	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
KFS85_18405	COG2827	Endonuclease containing a URI domain
KFS85_18410	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KFS85_18430	COG1196	nuclear chromosome segregation
KFS85_18435	COG2189	Belongs to the N(4) N(6)-methyltransferase family
KFS85_18445	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KFS85_18450	COG0459	protein refolding
KFS85_18465	COG1324	tolerance protein
KFS85_18475	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KFS85_18485	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
KFS85_18490	COG0511	ligase activity, forming carbon-carbon bonds
KFS85_18495	COG0439	Biotin carboxylase
KFS85_18510	COG2264	protein methyltransferase activity
KFS85_18535	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
KFS85_18575	COG0138	bifunctional purine biosynthesis protein purh
KFS85_18585	COG0151	Belongs to the GarS family
KFS85_18590	COG1289	transmembrane transporter activity
KFS85_18595	COG2814	Major facilitator Superfamily
KFS85_18630	COG2816	NAD+ diphosphatase activity
KFS85_18670	COG2906	2 iron, 2 sulfur cluster binding
KFS85_18700	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
KFS85_18715	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KFS85_18720	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KFS85_18725	COG0730	response to heat
KFS85_18730	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
KFS85_18730	COG4124	Belongs to the glycosyl hydrolase 26 family
KFS85_18740	COG0134	indole-3-glycerol-phosphate synthase activity
KFS85_18745	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KFS85_18765	COG1597	lipid kinase activity
KFS85_18780	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
KFS85_18795	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KFS85_18800	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KFS85_18800	COG2111	Na H antiporter
KFS85_18805	COG1006	Multisubunit Na H antiporter MnhC subunit
KFS85_18810	COG0651	ATP synthesis coupled electron transport
KFS85_18820	COG2212	antiporter activity
KFS85_18825	COG1320	monovalent cation:proton antiporter activity
KFS85_18830	COG0530	calcium, potassium:sodium antiporter activity
KFS85_18845	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
KFS85_18865	COG3104	oligopeptide transport
KFS85_18880	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KFS85_18905	COG3227	Zinc metalloprotease (Elastase)
KFS85_18910	COG0513	Belongs to the DEAD box helicase family
KFS85_18925	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KFS85_18930	COG1285	pathogenesis
KFS85_18950	COG2354	Protein conserved in bacteria
KFS85_18970	COG1196	nuclear chromosome segregation
KFS85_18970	COG3264	Mechanosensitive ion channel
KFS85_18980	COG0604	alcohol dehydrogenase
KFS85_18980	COG3321	synthase
KFS85_18980	COG1028	Short-chain dehydrogenase reductase Sdr
KFS85_19000	COG1595	DNA-templated transcription, initiation
KFS85_19015	COG1802	Transcriptional regulator
KFS85_19030	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
KFS85_19070	COG1414	Transcriptional regulator
KFS85_19075	COG0738	Major facilitator superfamily
KFS85_19080	COG3254	rhamnose metabolic process
KFS85_19085	COG4948	Mandelate Racemase Muconate Lactonizing
KFS85_19090	COG0179	Fumarylacetoacetate (FAA) hydrolase
KFS85_19095	COG1028	Short-chain dehydrogenase reductase Sdr
KFS85_19110	COG0546	phosphoglycolate phosphatase activity
KFS85_19125	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KFS85_19140	COG4807	Protein conserved in bacteria
KFS85_19165	COG0708	Exodeoxyribonuclease III
KFS85_19180	COG4773	Receptor
KFS85_19210	COG1396	sequence-specific DNA binding
KFS85_19210	COG3800	Transcriptional regulator
KFS85_19230	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KFS85_19235	COG1074	ATP-dependent DNA helicase activity
KFS85_19240	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
KFS85_19245	COG1127	ABC transporter
KFS85_19250	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
KFS85_19255	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
KFS85_19270	COG2853	Lipoprotein
KFS85_19275	COG0386	Belongs to the glutathione peroxidase family
KFS85_19280	COG1322	Protein conserved in bacteria
KFS85_19295	COG1285	pathogenesis
KFS85_19300	COG4191	Histidine kinase
KFS85_19305	COG4566	intracellular signal transduction
KFS85_19310	COG0531	amino acid
KFS85_19320	COG1929	Belongs to the glycerate kinase type-1 family
KFS85_19410	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KFS85_19430	COG0628	permease
KFS85_19435	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KFS85_19440	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KFS85_19450	COG0753	catalase activity
KFS85_19460	COG2197	response regulator
KFS85_19465	COG4585	Histidine kinase
KFS85_19475	COG1131	(ABC) transporter
KFS85_19535	COG4152	abc transporter atp-binding protein
KFS85_19545	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KFS85_19550	COG1136	(ABC) transporter
KFS85_19550	COG0577	efflux transmembrane transporter activity
KFS85_19555	COG0577	efflux transmembrane transporter activity
KFS85_19580	COG0697	spore germination
KFS85_19595	COG0180	Tryptophanyl-tRNA synthetase
KFS85_19605	COG3237	CsbD-like
KFS85_19635	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
KFS85_19640	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
KFS85_19640	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
KFS85_19650	COG3228	Belongs to the MtfA family
KFS85_19680	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KFS85_19705	COG4695	Portal protein
KFS85_19960	COG2084	Dehydrogenase
KFS85_19965	COG1902	pentaerythritol trinitrate reductase activity
KFS85_19975	COG2814	Major facilitator Superfamily
KFS85_19985	COG0583	DNA-binding transcription factor activity
KFS85_19995	COG1846	Transcriptional regulator
KFS85_20000	COG1764	response to oxidative stress
KFS85_20020	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KFS85_20025	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KFS85_20030	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KFS85_20050	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
KFS85_20060	COG0697	spore germination
KFS85_20065	COG0523	cobalamin synthesis protein
KFS85_20075	COG1742	UPF0060 membrane protein
KFS85_20085	COG3245	cytochrome
KFS85_20095	COG1960	acyl-CoA dehydrogenase activity
KFS85_20100	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KFS85_20115	COG1278	Cold shock
KFS85_20140	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KFS85_20145	COG3387	PFAM Glycoside hydrolase 15-related
KFS85_20155	COG0745	RESPONSE REGULATOR receiver
KFS85_20160	COG0784	Response regulator, receiver
KFS85_20160	COG4191	Histidine kinase
KFS85_20170	COG1404	Belongs to the peptidase S8 family
KFS85_20180	COG3100	YcgL domain-containing protein
KFS85_20185	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KFS85_20195	COG0463	Glycosyl transferase, family 2
KFS85_20205	COG1028	Short-chain dehydrogenase reductase Sdr
KFS85_20235	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KFS85_20250	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KFS85_20270	COG1294	oxidase, subunit
KFS85_20275	COG1271	oxidase subunit
KFS85_20290	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KFS85_20295	COG0408	coproporphyrinogen oxidase activity
KFS85_20305	COG2323	membrane
KFS85_20310	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KFS85_20310	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KFS85_20325	COG0589	response to stress
KFS85_20340	COG0210	DNA helicase
KFS85_20410	COG0463	Glycosyl transferase, family 2
KFS85_20425	COG1192	Involved in chromosome partitioning
KFS85_20430	COG0357	Ribosomal RNA small subunit methyltransferase G
KFS85_20435	COG2091	lysine biosynthetic process via aminoadipic acid
KFS85_20460	COG0477	Major facilitator Superfamily
KFS85_20480	COG1971	Probably functions as a manganese efflux pump
KFS85_20490	COG2205	protein histidine kinase activity
KFS85_20505	COG3459	Glycosyltransferase 36 associated
KFS85_20510	COG2211	Major facilitator Superfamily
KFS85_20515	COG3265	gluconokinase activity
KFS85_20535	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KFS85_20545	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KFS85_20550	COG2226	methyltransferase
KFS85_20570	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KFS85_20620	COG0246	Mannitol dehydrogenase
KFS85_20625	COG1472	Belongs to the glycosyl hydrolase 3 family
KFS85_20635	COG4948	Mandelate Racemase Muconate Lactonizing
KFS85_20645	COG3661	Belongs to the glycosyl hydrolase 67 family
KFS85_20655	COG2115	Belongs to the xylose isomerase family
KFS85_20660	COG0037	tRNA processing
KFS85_20680	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KFS85_20690	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KFS85_20700	COG0805	protein transport
KFS85_20710	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KFS85_20710	COG0519	Catalyzes the synthesis of GMP from XMP
KFS85_20715	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KFS85_20730	COG0210	DNA helicase
KFS85_20735	COG1435	thymidine kinase activity
KFS85_20745	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
KFS85_20755	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
KFS85_20770	COG1119	ATPase activity
KFS85_20780	COG0706	membrane insertase activity
KFS85_20785	COG0594	ribonuclease P activity