locus-tag	class	description
KAF26_00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KAF26_00020	COG0187	DNA topoisomerase II activity
KAF26_00025	COG1266	CAAX protease self-immunity
KAF26_00030	COG0501	Belongs to the peptidase M48B family
KAF26_00070	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KAF26_00085	COG1280	lysine exporter protein (LysE YggA)
KAF26_00100	COG4772	TonB-dependent receptor
KAF26_00110	COG3284	Transcriptional regulator
KAF26_00115	COG1012	belongs to the aldehyde dehydrogenase family
KAF26_00150	COG1304	FMN binding
KAF26_00180	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KAF26_00255	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KAF26_00275	COG4771	TonB-dependent receptor
KAF26_00320	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
KAF26_00335	COG3507	Belongs to the glycosyl hydrolase 43 family
KAF26_00340	COG1609	Transcriptional regulator
KAF26_00350	COG1028	Short-chain dehydrogenase reductase Sdr
KAF26_00365	COG3186	Phenylalanine-4-hydroxylase
KAF26_00370	COG1522	sequence-specific DNA binding
KAF26_00390	COG1752	Esterase of the alpha-beta hydrolase superfamily
KAF26_00410	COG0671	phosphoesterase, PA-phosphatase related
KAF26_00425	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KAF26_00460	COG1929	Belongs to the glycerate kinase type-1 family
KAF26_00470	COG0531	amino acid
KAF26_00475	COG4566	intracellular signal transduction
KAF26_00480	COG4191	Histidine kinase
KAF26_00500	COG1322	Protein conserved in bacteria
KAF26_00505	COG0386	Belongs to the glutathione peroxidase family
KAF26_00510	COG2853	Lipoprotein
KAF26_00525	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
KAF26_00530	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
KAF26_00535	COG1127	ABC transporter
KAF26_00540	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
KAF26_00545	COG1074	ATP-dependent DNA helicase activity
KAF26_00550	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KAF26_00570	COG0537	adenosine 5'-monophosphoramidase activity
KAF26_00635	COG0477	Major facilitator Superfamily
KAF26_00640	COG0302	gtp cyclohydrolase
KAF26_00665	COG0730	response to heat
KAF26_00680	COG2951	lytic endotransglycosylase activity
KAF26_00745	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
KAF26_00750	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
KAF26_00755	COG0493	'glutamate synthase
KAF26_00760	COG0067	glutamate synthase
KAF26_00760	COG0069	glutamate synthase activity
KAF26_00760	COG0070	glutamate synthase
KAF26_00805	COG1111	helicase
KAF26_00805	COG1205	dead DEAH box helicase
KAF26_00840	COG2271	Major facilitator Superfamily
KAF26_00895	COG1192	Involved in chromosome partitioning
KAF26_00900	COG2062	phosphohistidine phosphatase, SixA
KAF26_00910	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KAF26_00915	COG2050	protein possibly involved in aromatic compounds catabolism
KAF26_00925	COG2267	carboxylic ester hydrolase activity
KAF26_00940	COG1881	PFAM PEBP family protein
KAF26_00945	COG1968	undecaprenyl-diphosphatase activity
KAF26_00950	COG0174	glutamine synthetase
KAF26_00955	COG0347	Belongs to the P(II) protein family
KAF26_00960	COG0004	ammonium transporteR
KAF26_00965	COG3852	Histidine kinase
KAF26_00970	COG2204	response regulator
KAF26_00975	COG2032	superoxide dismutase activity
KAF26_00980	COG2032	superoxide dismutase activity
KAF26_00990	COG0183	Belongs to the thiolase family
KAF26_01030	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
KAF26_01035	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
KAF26_01045	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KAF26_01055	COG0612	Peptidase, M16
KAF26_01065	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KAF26_01075	COG0596	Alpha beta hydrolase
KAF26_01085	COG0727	PFAM Uncharacterised protein family (UPF0153)
KAF26_01090	COG0318	PFAM AMP-dependent synthetase and ligase
KAF26_01105	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KAF26_01115	COG1181	Belongs to the D-alanine--D-alanine ligase family
KAF26_01130	COG4232	protein-disulfide reductase activity
KAF26_01135	COG0564	pseudouridine synthase activity
KAF26_01155	COG0339	signal peptide processing
KAF26_01170	COG0583	DNA-binding transcription factor activity
KAF26_01175	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
KAF26_01180	COG2224	Isocitrate lyase
KAF26_01215	COG0659	secondary active sulfate transmembrane transporter activity
KAF26_01250	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KAF26_01255	COG2130	NADP-dependent
KAF26_01270	COG1187	pseudouridine synthase activity
KAF26_01295	COG0084	hydrolase, TatD family'
KAF26_01310	COG0842	Transport permease protein
KAF26_01315	COG1131	(ABC) transporter
KAF26_01320	COG0633	Ferredoxin
KAF26_01320	COG0543	2 iron, 2 sulfur cluster binding
KAF26_01330	COG1476	TRANSCRIPTIONal
KAF26_01340	COG4555	ABC transporter
KAF26_01360	COG0625	glutathione transferase activity
KAF26_01435	COG1199	ATP-dependent helicase activity
KAF26_01495	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KAF26_01515	COG0628	permease
KAF26_01525	COG0129	dihydroxy-acid dehydratase activity
KAF26_01530	COG2133	pyrroloquinoline quinone binding
KAF26_01580	COG0754	glutathionylspermidine amidase activity
KAF26_01590	COG0714	Associated with various cellular activities
KAF26_01625	COG2814	Major facilitator Superfamily
KAF26_01635	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KAF26_01650	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KAF26_01655	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KAF26_01680	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KAF26_01700	COG1028	Short-chain dehydrogenase reductase Sdr
KAF26_01715	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
KAF26_01725	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KAF26_01755	COG0606	chelatase, subunit chli
KAF26_01760	COG2960	long-chain fatty acid transporting porin activity
KAF26_01785	COG1166	arginine decarboxylase activity
KAF26_01800	COG2755	lipolytic protein G-D-S-L family
KAF26_01800	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
KAF26_01805	COG0583	DNA-binding transcription factor activity
KAF26_01825	COG4221	oxidoreductase activity
KAF26_01845	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KAF26_01865	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KAF26_01875	COG2814	Major facilitator Superfamily
KAF26_01885	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
KAF26_01890	COG0739	heme binding
KAF26_01895	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KAF26_01925	COG1064	alcohol dehydrogenase
KAF26_01930	COG2234	aminopeptidase activity
KAF26_01940	COG4942	peptidase
KAF26_01945	COG0793	Belongs to the peptidase S41A family
KAF26_02000	COG1565	acr, cog1565
KAF26_02000	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KAF26_02005	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KAF26_02010	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
KAF26_02040	COG0109	protoheme IX farnesyltransferase activity
KAF26_02055	COG0358	DNA primase activity
KAF26_02060	COG1295	ribonuclease BN
KAF26_02080	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KAF26_02085	COG2308	Evidence 4 Homologs of previously reported genes of
KAF26_02125	COG0531	amino acid
KAF26_02135	COG4948	Mandelate Racemase Muconate Lactonizing
KAF26_02145	COG4771	TonB-dependent receptor
KAF26_02150	COG3023	N-Acetylmuramoyl-L-alanine amidase
KAF26_02200	COG5383	Protein conserved in bacteria
KAF26_02215	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KAF26_02220	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KAF26_02235	COG1652	LysM domain
KAF26_02245	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KAF26_02250	COG1518	maintenance of DNA repeat elements
KAF26_02300	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
KAF26_02310	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KAF26_02315	COG3118	belongs to the thioredoxin family
KAF26_02325	COG2884	Cell division ATP-binding protein ftsE
KAF26_02330	COG2177	Part of the ABC transporter FtsEX involved in
KAF26_02335	COG2201	protein-glutamate methylesterase activity
KAF26_02340	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KAF26_02345	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KAF26_02350	COG2860	membrane
KAF26_02355	COG1252	NADH dehydrogenase
KAF26_02365	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KAF26_02375	COG0534	Mate efflux family protein
KAF26_02380	COG0616	signal peptide processing
KAF26_02390	COG1028	Short-chain dehydrogenase reductase Sdr
KAF26_02405	COG0009	L-threonylcarbamoyladenylate synthase
KAF26_02410	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KAF26_02410	COG1754	DNA topoisomerase type I activity
KAF26_02415	COG1714	RDD family
KAF26_02430	COG0758	DNA mediated transformation
KAF26_02435	COG1652	LysM domain
KAF26_02440	COG0242	peptide deformylase activity
KAF26_02445	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KAF26_02450	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KAF26_02450	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KAF26_02455	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KAF26_02490	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KAF26_02495	COG1247	-acetyltransferase
KAF26_02505	COG1490	D-aminoacyl-tRNA deacylase activity
KAF26_02510	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KAF26_02540	COG1609	Transcriptional regulator
KAF26_02550	COG0366	Alpha amylase catalytic
KAF26_02555	COG0366	Alpha amylase catalytic
KAF26_02605	COG1309	transcriptional regulator
KAF26_02645	COG0840	transmembrane signaling receptor activity
KAF26_02660	COG3546	catalase activity
KAF26_02665	COG3685	Protein conserved in bacteria
KAF26_02670	COG3685	Protein conserved in bacteria
KAF26_02680	COG1028	Short-chain dehydrogenase reductase Sdr
KAF26_02690	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
KAF26_02705	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KAF26_02720	COG0028	Belongs to the TPP enzyme family
KAF26_02725	COG4191	Histidine kinase
KAF26_02730	COG2204	response regulator
KAF26_02760	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
KAF26_02765	COG0732	type I restriction modification DNA specificity domain
KAF26_02790	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KAF26_02790	COG1648	precorrin-2 dehydrogenase activity
KAF26_02800	COG1116	anion transmembrane transporter activity
KAF26_02800	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KAF26_02805	COG2223	nitrite transmembrane transporter activity
KAF26_02810	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KAF26_02815	COG2146	nitrite reductase [NAD(P)H] activity
KAF26_02820	COG0243	molybdopterin cofactor binding
KAF26_02845	COG1640	4-alpha-glucanotransferase
KAF26_02850	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KAF26_02870	COG0745	RESPONSE REGULATOR receiver
KAF26_02895	COG0181	hydroxymethylbilane synthase activity
KAF26_02910	COG1733	regulation of RNA biosynthetic process
KAF26_02925	COG1505	serine-type exopeptidase activity
KAF26_02930	COG0436	Aminotransferase
KAF26_02940	COG2832	Protein of unknown function (DUF454)
KAF26_02950	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KAF26_02970	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
KAF26_02995	COG2226	methyltransferase
KAF26_03000	COG0308	aminopeptidase N
KAF26_03005	COG0596	Alpha beta hydrolase
KAF26_03005	COG0508	dehydrogenase complex catalyzes the overall conversion of
KAF26_03025	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KAF26_03030	COG1077	Cell shape determining protein MreB Mrl
KAF26_03035	COG1792	Involved in formation and maintenance of cell shape
KAF26_03045	COG0768	penicillin binding
KAF26_03050	COG0772	Belongs to the SEDS family
KAF26_03065	COG2951	lytic endotransglycosylase activity
KAF26_03075	COG1686	Belongs to the peptidase S11 family
KAF26_03110	COG0321	lipoyl(octanoyl) transferase activity
KAF26_03115	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KAF26_03140	COG1051	belongs to the nudix hydrolase family
KAF26_03140	COG1056	cytidyltransferase-related domain
KAF26_03175	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KAF26_03180	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KAF26_03185	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
KAF26_03190	COG1561	YicC-like family, N-terminal region
KAF26_03195	COG0194	GDP metabolic process
KAF26_03200	COG1758	RNA polymerase activity
KAF26_03205	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KAF26_03230	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KAF26_03240	COG0254	rRNA binding
KAF26_03245	COG0372	Belongs to the citrate synthase family
KAF26_03260	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KAF26_03280	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KAF26_03285	COG0667	Aldo Keto reductase
KAF26_03295	COG4771	TonB-dependent receptor
KAF26_03315	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
KAF26_03320	COG4181	ATPase activity
KAF26_03335	COG0642	Histidine kinase
KAF26_03345	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KAF26_03350	COG0861	Integral membrane protein TerC family
KAF26_03355	COG1704	LemA family
KAF26_03400	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KAF26_03410	COG1215	transferase activity, transferring glycosyl groups
KAF26_03440	COG0242	peptide deformylase activity
KAF26_03450	COG0488	(ABC) transporter
KAF26_03455	COG0477	Major facilitator Superfamily
KAF26_03485	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KAF26_03495	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KAF26_03495	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KAF26_03510	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
KAF26_03515	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KAF26_03520	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
KAF26_03545	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
KAF26_03550	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
KAF26_03560	COG2205	protein histidine kinase activity
KAF26_03565	COG0745	RESPONSE REGULATOR receiver
KAF26_03570	COG0277	FAD linked oxidase domain protein
KAF26_03580	COG0792	nuclease activity
KAF26_03615	COG2001	Belongs to the MraZ family
KAF26_03620	COG0275	rRNA processing
KAF26_03625	COG3116	cell division
KAF26_03640	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KAF26_03665	COG1181	Belongs to the D-alanine--D-alanine ligase family
KAF26_03670	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KAF26_03680	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KAF26_03685	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
KAF26_03695	COG0739	heme binding
KAF26_03710	COG0494	nUDIX hydrolase
KAF26_03720	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KAF26_03745	COG2226	methyltransferase
KAF26_03785	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KAF26_03800	COG1090	epimerase
KAF26_03815	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
KAF26_03820	COG0673	inositol 2-dehydrogenase activity
KAF26_03825	COG2823	Periplasmic or secreted lipoprotein
KAF26_03835	COG2202	Pas domain
KAF26_03835	COG2205	protein histidine kinase activity
KAF26_03840	COG0784	Response regulator, receiver
KAF26_03845	COG4191	Histidine kinase
KAF26_03855	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KAF26_03890	COG3250	beta-galactosidase activity
KAF26_03905	COG2188	Transcriptional regulator
KAF26_03910	COG0738	Major facilitator superfamily
KAF26_03915	COG1609	Transcriptional regulator
KAF26_03920	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KAF26_03925	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KAF26_03930	COG0617	tRNA 3'-terminal CCA addition
KAF26_04000	COG2205	protein histidine kinase activity
KAF26_04015	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
KAF26_04020	COG3791	Glutathione-dependent formaldehyde-activating
KAF26_04060	COG0804	urea catabolic process
KAF26_04065	COG1228	amidohydrolase
KAF26_04085	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
KAF26_04110	COG0436	Aminotransferase
KAF26_04115	COG1162	GTPase activity
KAF26_04140	COG2211	Major facilitator Superfamily
KAF26_04150	COG1028	Short-chain dehydrogenase reductase Sdr
KAF26_04155	COG2851	Citrate transporter
KAF26_04170	COG0642	Histidine kinase
KAF26_04190	COG4191	Histidine kinase
KAF26_04200	COG1301	dicarboxylic acid transport
KAF26_04205	COG0281	malic enzyme
KAF26_04205	COG0280	phosphate acetyltransferase
KAF26_04290	COG1560	Kdo2-lipid A biosynthetic process
KAF26_04295	COG1519	Transferase
KAF26_04300	COG1538	Outer membrane efflux protein
KAF26_04305	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
KAF26_04315	COG3706	GGDEF domain
KAF26_04320	COG0473	3-isopropylmalate dehydrogenase activity
KAF26_04325	COG0066	3-isopropylmalate dehydratase activity
KAF26_04335	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KAF26_04345	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KAF26_04365	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KAF26_04370	COG0840	transmembrane signaling receptor activity
KAF26_04390	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
KAF26_04400	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
KAF26_04420	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KAF26_04430	COG0671	phosphoesterase, PA-phosphatase related
KAF26_04445	COG1940	carbohydrate kinase activity
KAF26_04455	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KAF26_04495	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
KAF26_04510	COG1773	rubredoxin
KAF26_04530	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KAF26_04540	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KAF26_04565	COG3079	Belongs to the UPF0149 family
KAF26_04570	COG0006	proline dipeptidase activity
KAF26_04590	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
KAF26_04620	COG0714	Associated with various cellular activities
KAF26_04650	COG1301	dicarboxylic acid transport
KAF26_04655	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KAF26_04680	COG0739	heme binding
KAF26_04685	COG1376	ErfK ybiS ycfS ynhG family protein
KAF26_04710	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
KAF26_04715	COG4149	molybdate abc transporter
KAF26_04720	COG0725	ABC transporter, periplasmic molybdate-binding protein
KAF26_04730	COG0640	Transcriptional regulator
KAF26_04750	COG3047	cAMP biosynthetic process
KAF26_04755	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KAF26_04800	COG0469	pyruvate kinase activity
KAF26_04805	COG3588	fructose-bisphosphate aldolase
KAF26_04810	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
KAF26_04850	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KAF26_04865	COG1648	precorrin-2 dehydrogenase activity
KAF26_04865	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KAF26_04880	COG0784	Response regulator, receiver
KAF26_04880	COG2198	Histidine kinase
KAF26_04880	COG2205	protein histidine kinase activity
KAF26_04885	COG1393	Belongs to the ArsC family
KAF26_04915	COG0175	sulfate reduction
KAF26_04920	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KAF26_04925	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KAF26_04935	COG2895	sulfate adenylyltransferase (ATP) activity
KAF26_04935	COG0529	Catalyzes the synthesis of activated sulfate
KAF26_04940	COG0840	transmembrane signaling receptor activity
KAF26_04980	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KAF26_05000	COG1609	Transcriptional regulator
KAF26_05015	COG0179	Fumarylacetoacetate (FAA) hydrolase
KAF26_05030	COG3273	potassium ion transport
KAF26_05030	COG0471	metal ion transport
KAF26_05040	COG2022	thiamine diphosphate biosynthetic process
KAF26_05065	COG0174	glutamine synthetase
KAF26_05070	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
KAF26_05080	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
KAF26_05115	COG3511	phospholipase C
KAF26_05125	COG0189	ligase activity
KAF26_05135	COG0745	RESPONSE REGULATOR receiver
KAF26_05150	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
KAF26_05215	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
KAF26_05215	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KAF26_05225	COG1262	PFAM Formylglycine-generating sulfatase enzyme
KAF26_05240	COG1174	glycine betaine transport
KAF26_05245	COG1125	glycine betaine transport
KAF26_05255	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KAF26_05260	COG0564	pseudouridine synthase activity
KAF26_05280	COG4993	Dehydrogenase
KAF26_05295	COG3387	PFAM Glycoside hydrolase 15-related
KAF26_05320	COG0454	-acetyltransferase
KAF26_05345	COG0542	response to heat
KAF26_05370	COG0019	diaminopimelate decarboxylase activity
KAF26_05375	COG4264	IucA IucC family
KAF26_05380	COG2814	Major facilitator Superfamily
KAF26_05385	COG4264	IucA IucC family
KAF26_05395	COG4772	TonB-dependent receptor
KAF26_05405	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KAF26_05405	COG4651	solute:proton antiporter activity
KAF26_05470	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KAF26_05470	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KAF26_05495	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
KAF26_05535	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KAF26_05540	COG1404	Belongs to the peptidase S8 family
KAF26_05575	COG1295	ribonuclease BN
KAF26_05580	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KAF26_05600	COG0521	Mo-molybdopterin cofactor biosynthetic process
KAF26_05720	COG3209	COG3209 Rhs family protein
KAF26_05775	COG4682	membrane
KAF26_05865	COG3179	chitinase
KAF26_06020	COG3537	Alpha-1,2-mannosidase
KAF26_06040	COG1472	Belongs to the glycosyl hydrolase 3 family
KAF26_06050	COG3525	Glycosyl hydrolase, family 20, catalytic domain
KAF26_06055	COG3858	chitin binding
KAF26_06055	COG1388	LysM domain
KAF26_06075	COG0837	glucose binding
KAF26_06085	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KAF26_06095	COG0494	nUDIX hydrolase
KAF26_06100	COG1218	3'(2'),5'-bisphosphate nucleotidase
KAF26_06105	COG3956	TIGRFAM MazG family protein
KAF26_06110	COG1742	UPF0060 membrane protein
KAF26_06120	COG0330	HflC and HflK could
KAF26_06190	COG2124	cytochrome p450
KAF26_06195	COG2124	cytochrome p450
KAF26_06200	COG1141	Ferredoxin
KAF26_06205	COG1028	Short-chain dehydrogenase reductase Sdr
KAF26_06210	COG2124	cytochrome p450
KAF26_06215	COG0142	geranyltranstransferase activity
KAF26_06220	COG1657	PFAM Prenyltransferase squalene oxidase
KAF26_06230	COG1304	FMN binding
KAF26_06265	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KAF26_06270	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KAF26_06275	COG0463	Glycosyl transferase, family 2
KAF26_06280	COG0517	IMP dehydrogenase activity
KAF26_06285	COG2982	Protein involved in outer membrane biogenesis
KAF26_06290	COG1272	protein, Hemolysin III
KAF26_06295	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KAF26_06305	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KAF26_06310	COG0626	cystathionine gamma-synthase activity
KAF26_06315	COG0527	aspartate kinase activity
KAF26_06315	COG0460	homoserine dehydrogenase
KAF26_06320	COG2267	carboxylic ester hydrolase activity
KAF26_06330	COG1760	l-serine dehydratase
KAF26_06345	COG3038	cytochrome b561
KAF26_06365	COG2814	Major facilitator Superfamily
KAF26_06370	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KAF26_06380	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KAF26_06400	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KAF26_06405	COG0259	pyridoxamine-phosphate oxidase activity
KAF26_06445	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KAF26_06460	COG0519	Catalyzes the synthesis of GMP from XMP
KAF26_06475	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KAF26_06500	COG0840	transmembrane signaling receptor activity
KAF26_06510	COG1113	amino acid transport
KAF26_06530	COG2239	Acts as a magnesium transporter
KAF26_06535	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KAF26_06540	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KAF26_06550	COG1660	Displays ATPase and GTPase activities
KAF26_06560	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KAF26_06575	COG1137	ATPase activity
KAF26_06590	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
KAF26_06635	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KAF26_06660	COG0628	permease
KAF26_06670	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KAF26_06675	COG3178	'Phosphotransferase
KAF26_06690	COG1555	photosystem II stabilization
KAF26_06710	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KAF26_06715	COG1477	protein flavinylation
KAF26_06740	COG4774	siderophore transport
KAF26_06745	COG2146	nitrite reductase [NAD(P)H] activity
KAF26_06755	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KAF26_06760	COG0719	Fe-S assembly protein
KAF26_06765	COG0396	ATPase activity
KAF26_06770	COG0719	Fe-S assembly protein
KAF26_06785	COG0693	protein deglycase activity
KAF26_06800	COG0739	heme binding
KAF26_06815	COG1764	response to oxidative stress
KAF26_06825	COG0384	phenazine biosynthesis protein PhzF
KAF26_06830	COG0527	aspartate kinase activity
KAF26_06855	COG0142	geranyltranstransferase activity
KAF26_06860	COG0629	single-stranded DNA binding
KAF26_06880	COG3104	oligopeptide transport
KAF26_06885	COG1297	OPT oligopeptide transporter protein
KAF26_06890	COG0823	Involved in the tonB-independent uptake of proteins
KAF26_06890	COG1506	peptidase
KAF26_06915	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KAF26_06920	COG2879	small protein
KAF26_06925	COG1966	Carbon starvation protein
KAF26_06965	COG2211	Major facilitator Superfamily
KAF26_06995	COG0835	chemotaxis
KAF26_07000	COG0840	transmembrane signaling receptor activity
KAF26_07005	COG0840	transmembrane signaling receptor activity
KAF26_07010	COG0840	transmembrane signaling receptor activity
KAF26_07015	COG0643	Histidine kinase
KAF26_07015	COG2198	Histidine kinase
KAF26_07025	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KAF26_07045	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
KAF26_07055	COG2205	protein histidine kinase activity
KAF26_07095	COG0735	belongs to the Fur family
KAF26_07135	COG1529	Aldehyde oxidase and xanthine dehydrogenase
KAF26_07140	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
KAF26_07145	COG2080	2 iron, 2 sulfur cluster binding
KAF26_07255	COG1187	pseudouridine synthase activity
KAF26_07280	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KAF26_07300	COG1132	(ABC) transporter
KAF26_07395	COG1981	membrane
KAF26_07420	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KAF26_07425	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KAF26_07435	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KAF26_07445	COG0750	zinc metalloprotease
KAF26_07450	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
KAF26_07455	COG0575	Belongs to the CDS family
KAF26_07460	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KAF26_07470	COG0528	UMP kinase activity
KAF26_07480	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KAF26_07520	COG0024	Methionine aminopeptidase
KAF26_07535	COG1393	Belongs to the ArsC family
KAF26_07540	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KAF26_07550	COG0367	asparagine synthase
KAF26_07590	COG1566	PFAM secretion protein HlyD family protein
KAF26_07595	COG2814	Major facilitator Superfamily
KAF26_07630	COG0557	exoribonuclease II activity
KAF26_07640	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KAF26_07660	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KAF26_07680	COG0704	Plays a role in the regulation of phosphate uptake
KAF26_07690	COG0581	inorganic phosphate transmembrane transporter activity
KAF26_07700	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KAF26_07705	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KAF26_07725	COG0659	secondary active sulfate transmembrane transporter activity
KAF26_07735	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KAF26_07745	COG1024	Enoyl-CoA hydratase
KAF26_07805	COG0784	Response regulator, receiver
KAF26_07805	COG2205	protein histidine kinase activity
KAF26_07805	COG5002	protein histidine kinase activity
KAF26_07810	COG2733	membrane
KAF26_07830	COG0686	Belongs to the AlaDH PNT family
KAF26_07835	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KAF26_07840	COG1396	sequence-specific DNA binding
KAF26_07840	COG1917	Cupin 2, conserved barrel domain protein
KAF26_07845	COG1012	belongs to the aldehyde dehydrogenase family
KAF26_07865	COG2223	nitrite transmembrane transporter activity
KAF26_07875	COG0243	molybdopterin cofactor binding
KAF26_07890	COG0477	Major facilitator Superfamily
KAF26_07900	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KAF26_07905	COG0174	glutamine synthetase
KAF26_07910	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
KAF26_07915	COG0174	glutamine synthetase
KAF26_07930	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
KAF26_07950	COG3842	ATPase activity
KAF26_07955	COG1176	ABC-type spermidine putrescine transport system, permease component I
KAF26_07960	COG1177	transmembrane transport
KAF26_07965	COG1012	belongs to the aldehyde dehydrogenase family
KAF26_07980	COG4535	Mg2 and Co2 transporter CorC
KAF26_07995	COG1702	phosphate starvation-inducible protein PhoH
KAF26_08010	COG0741	lytic transglycosylase activity
KAF26_08015	COG0723	plastoquinol--plastocyanin reductase activity
KAF26_08020	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KAF26_08030	COG2857	Cytochrome c1
KAF26_08035	COG0625	glutathione transferase activity
KAF26_08040	COG2969	positive regulation of protein catabolic process
KAF26_08080	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
KAF26_08085	COG1028	Short-chain dehydrogenase reductase Sdr
KAF26_08090	COG2095	MarC family integral membrane protein
KAF26_08100	COG1611	Belongs to the LOG family
KAF26_08105	COG3275	phosphorelay sensor kinase activity
KAF26_08150	COG0556	nucleotide-excision repair
KAF26_08165	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KAF26_08170	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KAF26_08180	COG2902	Dehydrogenase
KAF26_08235	COG2925	Exonuclease
KAF26_08245	COG3844	kynureninase activity
KAF26_08255	COG0662	Cupin 2, conserved barrel domain protein
KAF26_08260	COG0288	reversible hydration of carbon dioxide
KAF26_08305	COG2197	response regulator
KAF26_08330	COG0316	Belongs to the HesB IscA family
KAF26_08365	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KAF26_08370	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KAF26_08375	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
KAF26_08385	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
KAF26_08405	COG1309	transcriptional regulator
KAF26_08420	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
KAF26_08435	COG1228	amidohydrolase
KAF26_08450	COG4221	oxidoreductase activity
KAF26_08490	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KAF26_08495	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KAF26_08500	COG0077	Prephenate dehydratase
KAF26_08500	COG1605	Chorismate mutase
KAF26_08525	COG0583	DNA-binding transcription factor activity
KAF26_08575	COG1136	(ABC) transporter
KAF26_08575	COG0577	efflux transmembrane transporter activity
KAF26_08605	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KAF26_08605	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KAF26_08610	COG1105	Belongs to the carbohydrate kinase PfkB family
KAF26_08615	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KAF26_08615	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
KAF26_08620	COG1609	Transcriptional regulator
KAF26_08630	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
KAF26_08635	COG0069	glutamate synthase activity
KAF26_08670	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KAF26_08685	COG1253	flavin adenine dinucleotide binding
KAF26_08695	COG0306	phosphate transporter
KAF26_08740	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
KAF26_08745	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
KAF26_08760	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
KAF26_08770	COG1238	metal cluster binding
KAF26_08785	COG1534	Rna-binding protein
KAF26_08790	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
KAF26_08795	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KAF26_08800	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KAF26_08805	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KAF26_08815	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KAF26_08820	COG1546	Belongs to the CinA family
KAF26_08825	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
KAF26_08830	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KAF26_08835	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KAF26_08840	COG2137	regulation of response to DNA damage stimulus
KAF26_08850	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
KAF26_08875	COG1741	Belongs to the pirin family
KAF26_08880	COG0583	DNA-binding transcription factor activity
KAF26_08900	COG0351	phosphomethylpyrimidine kinase
KAF26_08900	COG0352	thiamine-phosphate diphosphorylase activity
KAF26_08945	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
KAF26_08950	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KAF26_08960	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KAF26_08970	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
KAF26_08975	COG3734	2-keto-3-deoxy-galactonokinase
KAF26_08990	COG0800	Aldolase
KAF26_09025	COG2198	Histidine kinase
KAF26_09025	COG2205	protein histidine kinase activity
KAF26_09025	COG0784	Response regulator, receiver
KAF26_09030	COG1024	Enoyl-CoA hydratase
KAF26_09035	COG0318	PFAM AMP-dependent synthetase and ligase
KAF26_09100	COG0840	transmembrane signaling receptor activity
KAF26_09110	COG0840	transmembrane signaling receptor activity
KAF26_09120	COG0835	chemotaxis
KAF26_09130	COG0840	transmembrane signaling receptor activity
KAF26_09140	COG0840	transmembrane signaling receptor activity
KAF26_09145	COG0840	transmembrane signaling receptor activity
KAF26_09150	COG0840	transmembrane signaling receptor activity
KAF26_09160	COG0840	transmembrane signaling receptor activity
KAF26_09170	COG0840	transmembrane signaling receptor activity
KAF26_09175	COG0840	transmembrane signaling receptor activity
KAF26_09180	COG0840	transmembrane signaling receptor activity
KAF26_09185	COG0840	transmembrane signaling receptor activity
KAF26_09195	COG0745	RESPONSE REGULATOR receiver
KAF26_09205	COG0835	chemotaxis
KAF26_09210	COG1192	Involved in chromosome partitioning
KAF26_09220	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KAF26_09225	COG0643	Histidine kinase
KAF26_09225	COG0784	Response regulator, receiver
KAF26_09225	COG2198	Histidine kinase
KAF26_09230	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
KAF26_09275	COG1684	flagellar biosynthetic protein fliR
KAF26_09280	COG1987	bacterial-type flagellum assembly
KAF26_09290	COG3190	flagellar
KAF26_09340	COG1677	Flagellar hook-basal body complex protein FliE
KAF26_09375	COG1028	Short-chain dehydrogenase reductase Sdr
KAF26_09385	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KAF26_09405	COG2201	protein-glutamate methylesterase activity
KAF26_09415	COG2197	response regulator
KAF26_09435	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
KAF26_09440	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KAF26_09445	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KAF26_09450	COG1256	bacterial-type flagellum assembly
KAF26_09450	COG4786	Flagellar basal body rod
KAF26_09450	COG1256	bacterial-type flagellum assembly
KAF26_09450	COG4786	Flagellar basal body rod
KAF26_09465	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
KAF26_09480	COG1749	Flagellar hook protein flgE
KAF26_09490	COG1558	bacterial-type flagellum-dependent cell motility
KAF26_09500	COG0784	Response regulator, receiver
KAF26_09500	COG0835	chemotaxis
KAF26_09560	COG2915	High frequency lysogenization protein hflD homolog
KAF26_09565	COG0482	sulfurtransferase activity
KAF26_09585	COG0542	response to heat
KAF26_09595	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
KAF26_09605	COG0492	ferredoxin-NADP+ reductase activity
KAF26_09610	COG1674	ftsk spoiiie
KAF26_09630	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KAF26_09635	COG0038	chloride channel
KAF26_09690	COG1595	DNA-templated transcription, initiation
KAF26_09710	COG3038	cytochrome b561
KAF26_09740	COG2244	polysaccharide biosynthetic process
KAF26_09760	COG4106	trans-aconitate 2-methyltransferase activity
KAF26_09780	COG0438	transferase activity, transferring glycosyl groups
KAF26_09785	COG0438	transferase activity, transferring glycosyl groups
KAF26_09815	COG1132	(ABC) transporter
KAF26_09840	COG1530	ribonuclease E activity
KAF26_09855	COG0428	transporter
KAF26_09870	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
KAF26_09870	COG0316	Belongs to the HesB IscA family
KAF26_09890	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KAF26_09910	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KAF26_09915	COG2957	Belongs to the agmatine deiminase family
KAF26_09925	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KAF26_09930	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
KAF26_09935	COG0539	negative regulation of cytoplasmic translation
KAF26_09940	COG0776	regulation of translation
KAF26_09950	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
KAF26_09955	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KAF26_09965	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KAF26_09970	COG0183	Belongs to the thiolase family
KAF26_09975	COG1024	Enoyl-CoA hydratase
KAF26_09975	COG1250	3-hydroxyacyl-CoA dehydrogenase
KAF26_09990	COG0820	rRNA (adenine-C2-)-methyltransferase activity
KAF26_10000	COG1426	Protein conserved in bacteria
KAF26_10010	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KAF26_10020	COG0746	molybdenum cofactor guanylyltransferase activity
KAF26_10030	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KAF26_10035	COG0475	glutathione-regulated potassium exporter activity
KAF26_10035	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KAF26_10055	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KAF26_10065	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KAF26_10065	COG0519	Catalyzes the synthesis of GMP from XMP
KAF26_10070	COG0582	viral genome integration into host DNA
KAF26_10180	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KAF26_10185	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
KAF26_10195	COG0505	Belongs to the CarA family
KAF26_10205	COG2258	MOSC domain
KAF26_10210	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KAF26_10230	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KAF26_10240	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KAF26_10245	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
KAF26_10280	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KAF26_10295	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KAF26_10305	COG1663	tetraacyldisaccharide 4'-kinase activity
KAF26_10310	COG1132	(ABC) transporter
KAF26_10320	COG0811	peptide transport
KAF26_10340	COG4591	ABC-type transport system involved in lipoprotein release permease component
KAF26_10350	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
KAF26_10355	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KAF26_10365	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
KAF26_10370	COG2009	succinate dehydrogenase
KAF26_10390	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KAF26_10405	COG0129	dihydroxy-acid dehydratase activity
KAF26_10420	COG0395	ABC-type sugar transport system, permease component
KAF26_10455	COG2350	Protein conserved in bacteria
KAF26_10460	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KAF26_10465	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KAF26_10470	COG1187	pseudouridine synthase activity
KAF26_10495	COG0436	Aminotransferase
KAF26_10500	COG4133	protoheme IX ABC transporter activity
KAF26_10545	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KAF26_10550	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KAF26_10555	COG4988	ABC transporter
KAF26_10565	COG1294	oxidase, subunit
KAF26_10595	COG2801	Transposase and inactivated derivatives
KAF26_10600	COG2963	transposase activity
KAF26_10615	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
KAF26_10620	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
KAF26_10635	COG1024	Enoyl-CoA hydratase
KAF26_10645	COG1024	Enoyl-CoA hydratase
KAF26_10650	COG1024	Enoyl-CoA hydratase
KAF26_10690	COG0346	lactoylglutathione lyase activity
KAF26_10700	COG1304	FMN binding
KAF26_10705	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KAF26_10710	COG1649	PFAM Uncharacterised BCR, COG1649
KAF26_10780	COG2183	response to ionizing radiation
KAF26_10785	COG4191	Histidine kinase
KAF26_10785	COG0784	Response regulator, receiver
KAF26_10795	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
KAF26_10795	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KAF26_10815	COG3243	poly(R)-hydroxyalkanoic acid synthase
KAF26_10825	COG1183	phosphatidylcholine synthase activity
KAF26_10830	COG1028	Short-chain dehydrogenase reductase Sdr
KAF26_10845	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
KAF26_10855	COG0668	transmembrane transport
KAF26_10860	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
KAF26_10875	COG1914	H( )-stimulated, divalent metal cation uptake system
KAF26_10885	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
KAF26_10890	COG1501	Belongs to the glycosyl hydrolase 31 family
KAF26_10895	COG2963	transposase activity
KAF26_10950	COG1487	ribonuclease activity
KAF26_10955	COG4691	Plasmid stability protein
KAF26_10985	COG1960	acyl-CoA dehydrogenase activity
KAF26_10990	COG2226	methyltransferase
KAF26_10995	COG0646	methionine synthase
KAF26_10995	COG1410	methionine synthase
KAF26_11000	COG0646	methionine synthase
KAF26_11000	COG1410	methionine synthase
KAF26_11020	COG2900	Belongs to the SlyX family
KAF26_11035	COG0386	Belongs to the glutathione peroxidase family
KAF26_11045	COG1725	Transcriptional regulator
KAF26_11050	COG1131	(ABC) transporter
KAF26_11095	COG2885	chlorophyll binding
KAF26_11100	COG2850	peptidyl-arginine hydroxylation
KAF26_11150	COG1132	(ABC) transporter
KAF26_11160	COG0287	Prephenate dehydrogenase
KAF26_11160	COG1605	Chorismate mutase
KAF26_11165	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
KAF26_11170	COG0484	heat shock protein binding
KAF26_11175	COG0443	Heat shock 70 kDa protein
KAF26_11180	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KAF26_11185	COG1420	regulation of RNA biosynthetic process
KAF26_11190	COG0497	DNA recombination
KAF26_11195	COG0735	belongs to the Fur family
KAF26_11200	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KAF26_11210	COG2867	negative regulation of translational initiation
KAF26_11215	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
KAF26_11220	COG1404	Belongs to the peptidase S8 family
KAF26_11255	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KAF26_11270	COG0583	DNA-binding transcription factor activity
KAF26_11285	COG0415	Belongs to the DNA photolyase family
KAF26_11290	COG0305	Participates in initiation and elongation during chromosome replication
KAF26_11300	COG1960	acyl-CoA dehydrogenase activity
KAF26_11315	COG0084	hydrolase, TatD family'
KAF26_11320	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KAF26_11370	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KAF26_11395	COG0386	Belongs to the glutathione peroxidase family
KAF26_11410	COG1846	Transcriptional regulator
KAF26_11450	COG1472	Belongs to the glycosyl hydrolase 3 family
KAF26_11460	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KAF26_11465	COG4290	ribonuclease
KAF26_11475	COG0488	(ABC) transporter
KAF26_11480	COG0513	Belongs to the DEAD box helicase family
KAF26_11505	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
KAF26_11510	COG0657	acetylesterase activity
KAF26_11515	COG0625	glutathione transferase activity
KAF26_11525	COG0564	pseudouridine synthase activity
KAF26_11530	COG4681	YaeQ
KAF26_11535	COG2081	HI0933 family
KAF26_11555	COG1028	Short-chain dehydrogenase reductase Sdr
KAF26_11575	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KAF26_11580	COG0860	N-Acetylmuramoyl-L-alanine amidase
KAF26_11585	COG0802	atpase or kinase
KAF26_11590	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KAF26_11590	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
KAF26_11595	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KAF26_11640	COG1960	acyl-CoA dehydrogenase activity
KAF26_11650	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KAF26_11670	COG0438	transferase activity, transferring glycosyl groups
KAF26_11680	COG0438	transferase activity, transferring glycosyl groups
KAF26_11685	COG0438	transferase activity, transferring glycosyl groups
KAF26_11735	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KAF26_11740	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KAF26_11750	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KAF26_11785	COG1024	Enoyl-CoA hydratase
KAF26_11800	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KAF26_11820	COG0277	FAD linked oxidase domain protein
KAF26_11825	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KAF26_11840	COG0531	amino acid
KAF26_11845	COG0531	amino acid
KAF26_11850	COG0235	Class ii aldolase
KAF26_11855	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
KAF26_11860	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
KAF26_11880	COG0140	phosphoribosyl-ATP diphosphatase activity
KAF26_11880	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KAF26_11895	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KAF26_11910	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KAF26_11915	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
KAF26_11925	COG0124	histidyl-tRNA synthetase
KAF26_11930	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KAF26_11940	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KAF26_11950	COG2951	lytic endotransglycosylase activity
KAF26_11955	COG0083	homoserine kinase activity
KAF26_11960	COG0460	homoserine dehydrogenase
KAF26_11960	COG0527	aspartate kinase activity
KAF26_11975	COG1012	belongs to the aldehyde dehydrogenase family
KAF26_11990	COG0167	dihydroorotate dehydrogenase activity
KAF26_11995	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KAF26_12020	COG0671	phosphoesterase, PA-phosphatase related
KAF26_12035	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
KAF26_12125	COG0166	Belongs to the GPI family
KAF26_12140	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
KAF26_12150	COG0617	tRNA 3'-terminal CCA addition
KAF26_12170	COG0860	N-Acetylmuramoyl-L-alanine amidase
KAF26_12175	COG0477	Major facilitator Superfamily
KAF26_12180	COG2115	Belongs to the xylose isomerase family
KAF26_12185	COG1070	Carbohydrate kinase
KAF26_12205	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KAF26_12225	COG0165	Argininosuccinate lyase
KAF26_12230	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KAF26_12240	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
KAF26_12245	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KAF26_12250	COG0137	argininosuccinate synthase activity
KAF26_12255	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KAF26_12270	COG2166	iron-sulfur cluster assembly
KAF26_12340	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
KAF26_12360	COG4677	pectinesterase activity
KAF26_12380	COG0402	S-adenosylhomocysteine deaminase activity
KAF26_12385	COG3548	integral membrane protein
KAF26_12395	COG1509	lysine 2,3-aminomutase activity
KAF26_12400	COG2203	Gaf domain
KAF26_12400	COG3706	GGDEF domain
KAF26_12400	COG4251	negative regulation of phosphorylation
KAF26_12400	COG5001	Diguanylate cyclase
KAF26_12425	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KAF26_12430	COG1862	Preprotein translocase
KAF26_12440	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KAF26_12450	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KAF26_12460	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KAF26_12465	COG3291	Pkd domain containing protein
KAF26_12470	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KAF26_12475	COG0405	Gamma-glutamyltransferase
KAF26_12480	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
KAF26_12495	COG0742	ribosomal rna small subunit methyltransferase
KAF26_12520	COG4771	TonB-dependent receptor
KAF26_12565	COG0531	amino acid
KAF26_12580	COG0006	proline dipeptidase activity
KAF26_12590	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KAF26_12605	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KAF26_12610	COG3938	Belongs to the proline racemase family
KAF26_12620	COG0552	protein localization to endoplasmic reticulum
KAF26_12625	COG1194	a g-specific adenine glycosylase
KAF26_12670	COG0835	chemotaxis
KAF26_12675	COG0840	transmembrane signaling receptor activity
KAF26_12680	COG0840	transmembrane signaling receptor activity
KAF26_12700	COG5001	Diguanylate cyclase
KAF26_12700	COG3300	MHYT domain
KAF26_12705	COG1185	polyribonucleotide nucleotidyltransferase activity
KAF26_12730	COG0195	Participates in both transcription termination and antitermination
KAF26_12745	COG1007	ATP synthesis coupled electron transport
KAF26_12780	COG1034	ATP synthesis coupled electron transport
KAF26_12785	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
KAF26_12790	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
KAF26_12795	COG0649	NAD binding
KAF26_12800	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KAF26_12810	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KAF26_12830	COG1028	Short-chain dehydrogenase reductase Sdr
KAF26_12850	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KAF26_12895	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KAF26_12910	COG2890	protein-(glutamine-N5) methyltransferase activity
KAF26_12920	COG0688	phosphatidylethanolamine metabolic process
KAF26_12925	COG0741	lytic transglycosylase activity
KAF26_12930	COG0433	COG0433 Predicted ATPase
KAF26_12935	COG0494	nUDIX hydrolase
KAF26_12950	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KAF26_12970	COG1714	RDD family
KAF26_12975	COG0717	Belongs to the dCTP deaminase family
KAF26_12980	COG0489	protein tyrosine kinase activity
KAF26_12990	COG4771	TonB-dependent receptor
KAF26_12995	COG4771	TonB-dependent receptor
KAF26_13000	COG0457	Tetratricopeptide repeat
KAF26_13015	COG3590	peptidase
KAF26_13045	COG0697	spore germination
KAF26_13065	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KAF26_13070	COG2311	Membrane
KAF26_13075	COG1047	Peptidyl-prolyl cis-trans
KAF26_13080	COG0791	NLP P60 protein
KAF26_13085	COG0791	NLP P60 protein
KAF26_13100	COG1607	acyl-coa hydrolase
KAF26_13110	COG1301	dicarboxylic acid transport
KAF26_13115	COG1785	Belongs to the alkaline phosphatase family
KAF26_13125	COG0037	tRNA processing
KAF26_13130	COG1722	exodeoxyribonuclease VII activity
KAF26_13135	COG0142	geranyltranstransferase activity
KAF26_13145	COG1858	cytochrome C peroxidase
KAF26_13170	COG0515	serine threonine protein kinase
KAF26_13170	COG2815	serine threonine protein kinase
KAF26_13175	COG0631	protein serine/threonine phosphatase activity
KAF26_13265	COG0312	modulator of DNA gyrase
KAF26_13275	COG0312	modulator of DNA gyrase
KAF26_13295	COG2968	Membrane
KAF26_13310	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KAF26_13325	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KAF26_13340	COG0495	leucyl-tRNA aminoacylation
KAF26_13350	COG3118	belongs to the thioredoxin family
KAF26_13370	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
KAF26_13380	COG2040	homocysteine
KAF26_13385	COG0833	amino acid
KAF26_13395	COG0346	lactoylglutathione lyase activity
KAF26_13420	COG2878	Part of a membrane complex involved in electron transport
KAF26_13435	COG1595	DNA-templated transcription, initiation
KAF26_13460	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KAF26_13480	COG0251	oxidation-reduction process
KAF26_13490	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KAF26_13490	COG0392	lysyltransferase activity
KAF26_13520	COG2814	Major facilitator Superfamily
KAF26_13530	COG1902	pentaerythritol trinitrate reductase activity
KAF26_13535	COG2824	Alkylphosphonate utilization operon protein PhnA
KAF26_13540	COG1047	Peptidyl-prolyl cis-trans
KAF26_13545	COG1077	Cell shape determining protein MreB Mrl
KAF26_13580	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KAF26_13590	COG1451	nucleotide metabolic process
KAF26_13615	COG0784	Response regulator, receiver
KAF26_13615	COG2198	Histidine kinase
KAF26_13615	COG2205	protein histidine kinase activity
KAF26_13625	COG2186	Transcriptional regulator
KAF26_13630	COG3250	beta-galactosidase activity
KAF26_13695	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
KAF26_13695	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
KAF26_13695	COG1703	isobutyryl-CoA mutase activity
KAF26_13730	COG0183	Belongs to the thiolase family
KAF26_13740	COG0443	Heat shock 70 kDa protein
KAF26_13775	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
KAF26_13775	COG1793	dna ligase
KAF26_13780	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
KAF26_13780	COG1793	dna ligase
KAF26_13785	COG1201	RNA secondary structure unwinding
KAF26_13795	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KAF26_13800	COG1278	Cold shock
KAF26_13805	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
KAF26_13810	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
KAF26_13815	COG1472	Belongs to the glycosyl hydrolase 3 family
KAF26_13825	COG2954	triphosphatase activity
KAF26_13835	COG0745	RESPONSE REGULATOR receiver
KAF26_13845	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KAF26_13860	COG0681	Belongs to the peptidase S26 family
KAF26_13865	COG0481	GTPase activity
KAF26_13870	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KAF26_13900	COG2855	membrane
KAF26_13915	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KAF26_13935	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
KAF26_13945	COG0534	Mate efflux family protein
KAF26_13950	COG0335	large ribosomal subunit rRNA binding
KAF26_13955	COG0336	Belongs to the RNA methyltransferase TrmD family
KAF26_13960	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KAF26_13975	COG2070	2-Nitropropane dioxygenase
KAF26_13980	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KAF26_13995	COG3534	alpha-L-arabinofuranosidase
KAF26_14005	COG0475	glutathione-regulated potassium exporter activity
KAF26_14015	COG0625	glutathione transferase activity
KAF26_14020	COG1082	Xylose isomerase domain protein TIM barrel
KAF26_14030	COG1172	Belongs to the binding-protein-dependent transport system permease family
KAF26_14035	COG1172	Belongs to the binding-protein-dependent transport system permease family
KAF26_14040	COG1129	ABC transporter
KAF26_14045	COG1879	ABC-type sugar transport system periplasmic component
KAF26_14050	COG1012	belongs to the aldehyde dehydrogenase family
KAF26_14070	COG0129	dihydroxy-acid dehydratase activity
KAF26_14095	COG2207	Transcriptional regulator
KAF26_14115	COG1317	bacterial-type flagellum organization
KAF26_14140	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KAF26_14165	COG4794	Type iii secretion
KAF26_14195	COG0745	RESPONSE REGULATOR receiver
KAF26_14220	COG3152	Membrane
KAF26_14230	COG0156	8-amino-7-oxononanoate synthase activity
KAF26_14240	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
KAF26_14245	COG1845	cytochrome c oxidase, subunit III
KAF26_14250	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KAF26_14270	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
KAF26_14285	COG0196	riboflavin kinase activity
KAF26_14310	COG0728	peptidoglycan biosynthetic process
KAF26_14325	COG0211	Belongs to the bacterial ribosomal protein bL27 family
KAF26_14330	COG0261	This protein binds to 23S rRNA in the presence of protein L20
KAF26_14335	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KAF26_14340	COG0824	Thioesterase
KAF26_14350	COG1024	Enoyl-CoA hydratase
KAF26_14355	COG1946	Acyl-CoA thioesterase
KAF26_14365	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KAF26_14370	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
KAF26_14435	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KAF26_14480	COG1643	Atp-dependent helicase
KAF26_14485	COG0783	Belongs to the Dps family
KAF26_14490	COG0514	ATP-dependent DNA helicase (RecQ)
KAF26_14510	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KAF26_14515	COG0602	queuosine metabolic process
KAF26_14525	COG2885	chlorophyll binding
KAF26_14540	COG0848	biopolymer transport protein
KAF26_14550	COG0824	Thioesterase
KAF26_14555	COG2255	four-way junction helicase activity
KAF26_14560	COG3158	transport of potassium into the cell
KAF26_14565	COG0632	four-way junction helicase activity
KAF26_14575	COG0217	transcriptional regulatory protein
KAF26_14595	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
KAF26_14615	COG3142	Participates in the control of copper homeostasis
KAF26_14620	COG1446	asparaginase
KAF26_14640	COG2201	protein-glutamate methylesterase activity
KAF26_14645	COG2198	Histidine kinase
KAF26_14645	COG0784	Response regulator, receiver
KAF26_14645	COG0643	Histidine kinase
KAF26_14650	COG0840	transmembrane signaling receptor activity
KAF26_14655	COG0835	chemotaxis
KAF26_14670	COG0189	ligase activity
KAF26_14690	COG1199	ATP-dependent helicase activity
KAF26_14700	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KAF26_14705	COG1216	Glycosyl transferase, family 2
KAF26_14710	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KAF26_14730	COG4585	Histidine kinase
KAF26_14740	COG0850	regulation of cytokinetic process
KAF26_14745	COG2894	cell division
KAF26_14750	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
KAF26_14760	COG2205	protein histidine kinase activity
KAF26_14765	COG0745	RESPONSE REGULATOR receiver
KAF26_14775	COG2194	sulfuric ester hydrolase activity
KAF26_14795	COG2814	Major facilitator Superfamily
KAF26_14820	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KAF26_14820	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KAF26_14830	COG0753	catalase activity
KAF26_14840	COG4106	trans-aconitate 2-methyltransferase activity
KAF26_14855	COG1063	alcohol dehydrogenase
KAF26_14865	COG3459	Glycosyltransferase 36 associated
KAF26_14925	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KAF26_14935	COG0330	HflC and HflK could
KAF26_14940	COG0330	HflC and HflK could
KAF26_14945	COG0604	alcohol dehydrogenase
KAF26_14965	COG0678	peroxiredoxin activity
KAF26_14975	COG4953	penicillin-binding protein 1C
KAF26_14995	COG2373	Large extracellular alpha-helical protein
KAF26_15020	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KAF26_15035	COG0372	Belongs to the citrate synthase family
KAF26_15040	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KAF26_15055	COG0587	DNA-directed DNA polymerase activity
KAF26_15090	COG2161	toxin-antitoxin pair type II binding
KAF26_15095	COG4115	mRNA cleavage
KAF26_15115	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KAF26_15120	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KAF26_15125	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KAF26_15135	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KAF26_15140	COG1028	Short-chain dehydrogenase reductase Sdr
KAF26_15145	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KAF26_15150	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KAF26_15160	COG1399	metal-binding, possibly nucleic acid-binding protein
KAF26_15185	COG0714	Associated with various cellular activities
KAF26_15205	COG0537	adenosine 5'-monophosphoramidase activity
KAF26_15325	COG0314	molybdopterin synthase activity
KAF26_15330	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
KAF26_15335	COG0315	cyclic pyranopterin monophosphate synthase activity
KAF26_15345	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KAF26_15350	COG1234	tRNA 3'-trailer cleavage
KAF26_15360	COG0859	PFAM glycosyl transferase family 9
KAF26_15380	COG0631	protein serine/threonine phosphatase activity
KAF26_15400	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KAF26_15405	COG1388	LysM domain
KAF26_15405	COG3942	CHAP domain
KAF26_15440	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KAF26_15450	COG0544	peptidyl-prolyl cis-trans isomerase activity
KAF26_15490	COG0473	3-isopropylmalate dehydrogenase activity
KAF26_15505	COG4783	chaperone-mediated protein folding
KAF26_15520	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KAF26_15525	COG0248	Ppx GppA phosphatase
KAF26_15530	COG0438	transferase activity, transferring glycosyl groups
KAF26_15540	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KAF26_15550	COG3291	Pkd domain containing protein
KAF26_15555	COG2833	Protein of unknown function (DUF455)
KAF26_15575	COG0285	dihydrofolate synthase activity
KAF26_15580	COG0588	phosphoglycerate mutase activity
KAF26_15600	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
KAF26_15605	COG4208	sulfate ABC transporter
KAF26_15610	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
KAF26_15615	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
KAF26_15620	COG0156	8-amino-7-oxononanoate synthase activity
KAF26_15635	COG2885	chlorophyll binding
KAF26_15645	COG2814	Major facilitator Superfamily
KAF26_15660	COG0667	Aldo Keto reductase
KAF26_15670	COG1902	pentaerythritol trinitrate reductase activity
KAF26_15670	COG0446	pyridine nucleotide-disulphide oxidoreductase
KAF26_15715	COG0625	glutathione transferase activity
KAF26_15730	COG0039	L-malate dehydrogenase activity
KAF26_15740	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KAF26_15745	COG1217	gtp-binding protein TYPA
KAF26_15760	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
KAF26_15770	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
KAF26_15775	COG0203	ribosomal protein L17
KAF26_15800	COG0201	protein transport
KAF26_15810	COG1841	ribosomal large subunit assembly
KAF26_15840	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KAF26_15845	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KAF26_15855	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KAF26_15860	COG0255	Belongs to the universal ribosomal protein uL29 family
KAF26_15885	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KAF26_15890	COG0089	rRNA binding
KAF26_15895	COG0088	Forms part of the polypeptide exit tunnel
KAF26_15905	COG0051	transcription antitermination factor activity, RNA binding
KAF26_15910	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KAF26_15915	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KAF26_15930	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KAF26_15940	COG0222	ribosome binding
KAF26_15955	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KAF26_15960	COG0250	Participates in transcription elongation, termination and antitermination
KAF26_15965	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KAF26_15975	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KAF26_15995	COG0012	GTP binding
KAF26_16000	COG0193	aminoacyl-tRNA hydrolase activity
KAF26_16010	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KAF26_16020	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KAF26_16035	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
KAF26_16040	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KAF26_16090	COG0488	(ABC) transporter
KAF26_16130	COG3634	alkyl hydroperoxide reductase activity
KAF26_16135	COG0583	DNA-binding transcription factor activity
KAF26_16145	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KAF26_16150	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KAF26_16180	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KAF26_16185	COG0697	spore germination
KAF26_16225	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KAF26_16230	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KAF26_16240	COG2096	Adenosyltransferase
KAF26_16250	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
KAF26_16255	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KAF26_16260	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
KAF26_16265	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KAF26_16270	COG2967	ApaG domain
KAF26_16275	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KAF26_16335	COG2188	Transcriptional regulator
KAF26_16345	COG1450	Type ii and iii secretion system protein
KAF26_16360	COG3166	PFAM Fimbrial assembly family protein
KAF26_16365	COG3156	type II secretion system protein K
KAF26_16370	COG4795	General secretion pathway protein
KAF26_16375	COG2165	general secretion pathway protein
KAF26_16380	COG4970	Tfp pilus assembly protein FimT
KAF26_16385	COG2165	general secretion pathway protein
KAF26_16390	COG1459	type II secretion system
KAF26_16395	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KAF26_16400	COG1404	Belongs to the peptidase S8 family
KAF26_16405	COG5295	Hep Hag repeat protein
KAF26_16415	COG0840	transmembrane signaling receptor activity
KAF26_16420	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KAF26_16420	COG0047	phosphoribosylformylglycinamidine synthase activity
KAF26_16425	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KAF26_16430	COG4974	Belongs to the 'phage' integrase family
KAF26_16455	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KAF26_16460	COG2927	DNA polymerase III (CHI subunit)
KAF26_16495	COG1183	phosphatidylcholine synthase activity
KAF26_16505	COG0442	prolyl-tRNA aminoacylation
KAF26_16520	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
KAF26_16525	COG1127	ABC transporter
KAF26_16530	COG3218	ABC-type transport auxiliary lipoprotein component
KAF26_16530	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
KAF26_16560	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KAF26_16565	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KAF26_16570	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
KAF26_16570	COG0662	Cupin 2, conserved barrel domain protein
KAF26_16595	COG2086	electron transfer activity
KAF26_16610	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
KAF26_16610	COG0546	phosphoglycolate phosphatase activity
KAF26_16615	COG0277	FAD linked oxidase domain protein
KAF26_16620	COG0300	oxidoreductase activity
KAF26_16645	COG0493	'glutamate synthase
KAF26_16690	COG0438	transferase activity, transferring glycosyl groups
KAF26_16690	COG1216	Glycosyl transferase, family 2
KAF26_16695	COG0438	transferase activity, transferring glycosyl groups
KAF26_16695	COG1216	Glycosyl transferase, family 2
KAF26_16700	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KAF26_16715	COG0626	cystathionine gamma-synthase activity
KAF26_16745	COG0625	glutathione transferase activity
KAF26_16755	COG0513	Belongs to the DEAD box helicase family
KAF26_16760	COG0720	synthase
KAF26_16770	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
KAF26_16775	COG1956	GAF domain-containing protein
KAF26_16785	COG4206	TonB-dependent receptor
KAF26_16790	COG0546	phosphoglycolate phosphatase activity
KAF26_16795	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KAF26_16815	COG0339	signal peptide processing
KAF26_16830	COG2217	Heavy metal translocating P-type atpase
KAF26_16845	COG2132	Multicopper oxidase
KAF26_16860	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KAF26_16870	COG1136	(ABC) transporter
KAF26_16875	COG1136	(ABC) transporter
KAF26_16875	COG0577	efflux transmembrane transporter activity
KAF26_16880	COG0577	efflux transmembrane transporter activity
KAF26_16880	COG1136	(ABC) transporter
KAF26_16885	COG1136	(ABC) transporter
KAF26_16885	COG0577	efflux transmembrane transporter activity
KAF26_16905	COG4191	Histidine kinase
KAF26_16915	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KAF26_16930	COG0355	proton-transporting ATP synthase activity, rotational mechanism
KAF26_16945	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KAF26_16955	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KAF26_16965	COG0356	it plays a direct role in the translocation of protons across the membrane
KAF26_16980	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KAF26_16985	COG0508	dehydrogenase complex catalyzes the overall conversion of
KAF26_17020	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KAF26_17025	COG0697	spore germination
KAF26_17030	COG1666	GTP binding
KAF26_17040	COG1187	pseudouridine synthase activity
KAF26_17065	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KAF26_17065	COG2205	protein histidine kinase activity
KAF26_17090	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KAF26_17165	COG0842	Transport permease protein
KAF26_17170	COG1131	(ABC) transporter
KAF26_17175	COG0025	NhaP-type Na H and K H
KAF26_17185	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
KAF26_17190	COG1573	uracil-dna glycosylase
KAF26_17200	COG3384	dioxygenase
KAF26_17225	COG0667	Aldo Keto reductase
KAF26_17235	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KAF26_17240	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KAF26_17260	COG3706	GGDEF domain
KAF26_17265	COG2146	nitrite reductase [NAD(P)H] activity
KAF26_17270	COG5001	Diguanylate cyclase
KAF26_17300	COG4106	trans-aconitate 2-methyltransferase activity
KAF26_17310	COG2076	Multidrug Resistance protein
KAF26_17320	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KAF26_17345	COG3279	Response regulator of the LytR AlgR family
KAF26_17350	COG3275	phosphorelay sensor kinase activity
KAF26_17375	COG0531	amino acid
KAF26_17385	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
KAF26_17385	COG5297	Belongs to the glycosyl hydrolase family 6
KAF26_17400	COG0741	lytic transglycosylase activity
KAF26_17415	COG2207	Transcriptional regulator
KAF26_17425	COG0598	Magnesium transport protein CorA
KAF26_17430	COG1113	amino acid transport
KAF26_17435	COG0697	spore germination
KAF26_17445	COG0583	DNA-binding transcription factor activity
KAF26_17460	COG5520	Belongs to the glycosyl hydrolase 30 family
KAF26_17565	COG0840	transmembrane signaling receptor activity
KAF26_17580	COG2353	YceI-like domain
KAF26_17610	COG0584	glycerophosphoryl diester phosphodiesterase
KAF26_17625	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
KAF26_17645	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KAF26_17665	COG2189	Belongs to the N(4) N(6)-methyltransferase family
KAF26_17675	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KAF26_17680	COG0459	protein refolding
KAF26_17695	COG1324	tolerance protein
KAF26_17705	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KAF26_17715	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
KAF26_17720	COG0511	ligase activity, forming carbon-carbon bonds
KAF26_17725	COG0439	Biotin carboxylase
KAF26_17740	COG2264	protein methyltransferase activity
KAF26_17760	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
KAF26_17765	COG4589	Belongs to the CDS family
KAF26_17785	COG2267	carboxylic ester hydrolase activity
KAF26_17790	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KAF26_17795	COG0138	bifunctional purine biosynthesis protein purh
KAF26_17800	COG0151	Belongs to the GarS family
KAF26_17805	COG1289	transmembrane transporter activity
KAF26_17810	COG2814	Major facilitator Superfamily
KAF26_17850	COG2816	NAD+ diphosphatase activity
KAF26_17890	COG2906	2 iron, 2 sulfur cluster binding
KAF26_17920	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
KAF26_17935	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KAF26_17940	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KAF26_17945	COG0730	response to heat
KAF26_17960	COG0134	indole-3-glycerol-phosphate synthase activity
KAF26_17965	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KAF26_17985	COG1597	lipid kinase activity
KAF26_18000	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
KAF26_18015	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KAF26_18020	COG2111	Na H antiporter
KAF26_18020	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KAF26_18025	COG1006	Multisubunit Na H antiporter MnhC subunit
KAF26_18030	COG0651	ATP synthesis coupled electron transport
KAF26_18035	COG1863	multisubunit Na H antiporter MnhE subunit
KAF26_18040	COG2212	antiporter activity
KAF26_18045	COG1320	monovalent cation:proton antiporter activity
KAF26_18050	COG0530	calcium, potassium:sodium antiporter activity
KAF26_18065	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
KAF26_18085	COG3104	oligopeptide transport
KAF26_18090	COG3483	tryptophan 2,3-dioxygenase activity
KAF26_18120	COG0508	dehydrogenase complex catalyzes the overall conversion of
KAF26_18150	COG0513	Belongs to the DEAD box helicase family
KAF26_18165	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KAF26_18175	COG2354	Protein conserved in bacteria
KAF26_18200	COG3264	Mechanosensitive ion channel
KAF26_18200	COG1196	nuclear chromosome segregation
KAF26_18205	COG1028	Short-chain dehydrogenase reductase Sdr
KAF26_18205	COG0604	alcohol dehydrogenase
KAF26_18205	COG3321	synthase
KAF26_18225	COG1595	DNA-templated transcription, initiation
KAF26_18240	COG1802	Transcriptional regulator
KAF26_18275	COG3052	prosthetic group binding
KAF26_18285	COG1414	Transcriptional regulator
KAF26_18290	COG0738	Major facilitator superfamily
KAF26_18295	COG3254	rhamnose metabolic process
KAF26_18300	COG4948	Mandelate Racemase Muconate Lactonizing
KAF26_18305	COG0179	Fumarylacetoacetate (FAA) hydrolase
KAF26_18310	COG1028	Short-chain dehydrogenase reductase Sdr
KAF26_18345	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KAF26_18360	COG4807	Protein conserved in bacteria
KAF26_18385	COG4773	Receptor
KAF26_18405	COG0823	Involved in the tonB-independent uptake of proteins
KAF26_18405	COG1506	peptidase
KAF26_18465	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KAF26_18485	COG0628	permease
KAF26_18490	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KAF26_18495	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KAF26_18500	COG0753	catalase activity
KAF26_18525	COG1136	(ABC) transporter
KAF26_18530	COG0577	efflux transmembrane transporter activity
KAF26_18550	COG0697	spore germination
KAF26_18565	COG0180	Tryptophanyl-tRNA synthetase
KAF26_18600	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
KAF26_18605	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
KAF26_18605	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
KAF26_18615	COG3228	Belongs to the MtfA family
KAF26_18645	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KAF26_18670	COG2084	Dehydrogenase
KAF26_18675	COG1902	pentaerythritol trinitrate reductase activity
KAF26_18700	COG1404	Belongs to the peptidase S8 family
KAF26_18705	COG2814	Major facilitator Superfamily
KAF26_18710	COG0583	DNA-binding transcription factor activity
KAF26_18730	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KAF26_18735	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KAF26_18745	COG1764	response to oxidative stress
KAF26_18750	COG1846	Transcriptional regulator
KAF26_18755	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
KAF26_18765	COG0697	spore germination
KAF26_18770	COG0523	cobalamin synthesis protein
KAF26_18780	COG1742	UPF0060 membrane protein
KAF26_18790	COG3245	cytochrome
KAF26_18800	COG1960	acyl-CoA dehydrogenase activity
KAF26_18805	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KAF26_18835	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KAF26_18840	COG3387	PFAM Glycoside hydrolase 15-related
KAF26_18845	COG0745	RESPONSE REGULATOR receiver
KAF26_18860	COG1404	Belongs to the peptidase S8 family
KAF26_18870	COG3100	YcgL domain-containing protein
KAF26_18875	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KAF26_18885	COG0463	Glycosyl transferase, family 2
KAF26_18895	COG1028	Short-chain dehydrogenase reductase Sdr
KAF26_18920	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KAF26_18935	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KAF26_18960	COG1294	oxidase, subunit
KAF26_18965	COG1271	oxidase subunit
KAF26_18985	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KAF26_18990	COG0408	coproporphyrinogen oxidase activity
KAF26_19000	COG2323	membrane
KAF26_19005	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KAF26_19005	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KAF26_19020	COG0589	response to stress
KAF26_19040	COG0210	DNA helicase
KAF26_19090	COG0463	Glycosyl transferase, family 2
KAF26_19100	COG1475	DNA binding
KAF26_19105	COG1192	Involved in chromosome partitioning
KAF26_19110	COG0357	Ribosomal RNA small subunit methyltransferase G
KAF26_19125	COG2091	lysine biosynthetic process via aminoadipic acid
KAF26_19150	COG0477	Major facilitator Superfamily
KAF26_19170	COG1971	Probably functions as a manganese efflux pump
KAF26_19175	COG2205	protein histidine kinase activity
KAF26_19185	COG3459	Glycosyltransferase 36 associated
KAF26_19190	COG2211	Major facilitator Superfamily
KAF26_19195	COG3265	gluconokinase activity
KAF26_19210	COG2911	Protein conserved in bacteria
KAF26_19215	COG0729	surface antigen
KAF26_19235	COG3132	Protein of unknown function, DUF480
KAF26_19280	COG0284	orotidine-5'-phosphate decarboxylase activity
KAF26_19295	COG1609	Transcriptional regulator
KAF26_19305	COG2937	Belongs to the GPAT DAPAT family
KAF26_19330	COG2211	Major facilitator Superfamily
KAF26_19345	COG3693	PFAM glycoside hydrolase, family 10
KAF26_19365	COG3386	PFAM SMP-30 Gluconolaconase
KAF26_19380	COG0246	Mannitol dehydrogenase
KAF26_19385	COG1472	Belongs to the glycosyl hydrolase 3 family
KAF26_19395	COG4948	Mandelate Racemase Muconate Lactonizing
KAF26_19405	COG3661	Belongs to the glycosyl hydrolase 67 family
KAF26_19415	COG2115	Belongs to the xylose isomerase family
KAF26_19420	COG0037	tRNA processing
KAF26_19440	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KAF26_19450	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KAF26_19460	COG0805	protein transport
KAF26_19470	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KAF26_19470	COG0519	Catalyzes the synthesis of GMP from XMP
KAF26_19475	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KAF26_19495	COG0210	DNA helicase
KAF26_19500	COG1435	thymidine kinase activity
KAF26_19510	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
KAF26_19535	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
KAF26_19550	COG1119	ATPase activity
KAF26_19570	COG0706	membrane insertase activity
KAF26_19575	COG0594	ribonuclease P activity