locus-tag	class	description
KBQ49_00085	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
KBQ49_00125	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KBQ49_00130	COG1404	Belongs to the peptidase S8 family
KBQ49_00165	COG1295	ribonuclease BN
KBQ49_00170	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KBQ49_00195	COG0521	Mo-molybdopterin cofactor biosynthetic process
KBQ49_00200	COG5297	Belongs to the glycosyl hydrolase family 6
KBQ49_00260	COG3537	Alpha-1,2-mannosidase
KBQ49_00285	COG1472	Belongs to the glycosyl hydrolase 3 family
KBQ49_00295	COG3525	Glycosyl hydrolase, family 20, catalytic domain
KBQ49_00300	COG1388	LysM domain
KBQ49_00300	COG3858	chitin binding
KBQ49_00315	COG0837	glucose binding
KBQ49_00325	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KBQ49_00335	COG0494	nUDIX hydrolase
KBQ49_00340	COG1218	3'(2'),5'-bisphosphate nucleotidase
KBQ49_00345	COG3956	TIGRFAM MazG family protein
KBQ49_00350	COG1742	UPF0060 membrane protein
KBQ49_00355	COG0330	HflC and HflK could
KBQ49_00390	COG0697	spore germination
KBQ49_00415	COG2124	cytochrome p450
KBQ49_00420	COG2124	cytochrome p450
KBQ49_00425	COG1141	Ferredoxin
KBQ49_00435	COG2124	cytochrome p450
KBQ49_00440	COG0142	geranyltranstransferase activity
KBQ49_00445	COG1657	PFAM Prenyltransferase squalene oxidase
KBQ49_00455	COG1304	FMN binding
KBQ49_00460	COG1960	acyl-CoA dehydrogenase activity
KBQ49_00475	COG4206	TonB-dependent receptor
KBQ49_00485	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KBQ49_00490	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KBQ49_00495	COG0463	Glycosyl transferase, family 2
KBQ49_00500	COG0517	IMP dehydrogenase activity
KBQ49_00505	COG2982	Protein involved in outer membrane biogenesis
KBQ49_00510	COG1272	protein, Hemolysin III
KBQ49_00515	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KBQ49_00525	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KBQ49_00530	COG0626	cystathionine gamma-synthase activity
KBQ49_00535	COG0460	homoserine dehydrogenase
KBQ49_00535	COG0527	aspartate kinase activity
KBQ49_00540	COG2267	carboxylic ester hydrolase activity
KBQ49_00550	COG1760	l-serine dehydratase
KBQ49_00565	COG3038	cytochrome b561
KBQ49_00585	COG2814	Major facilitator Superfamily
KBQ49_00590	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KBQ49_00600	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KBQ49_00605	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KBQ49_00620	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KBQ49_00680	COG0519	Catalyzes the synthesis of GMP from XMP
KBQ49_00695	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KBQ49_00715	COG0840	transmembrane signaling receptor activity
KBQ49_00725	COG1113	amino acid transport
KBQ49_00745	COG2239	Acts as a magnesium transporter
KBQ49_00750	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KBQ49_00755	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KBQ49_00765	COG1660	Displays ATPase and GTPase activities
KBQ49_00775	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KBQ49_00790	COG1137	ATPase activity
KBQ49_00805	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
KBQ49_00850	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KBQ49_00875	COG0628	permease
KBQ49_00885	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KBQ49_00890	COG3178	'Phosphotransferase
KBQ49_00905	COG1555	photosystem II stabilization
KBQ49_00925	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KBQ49_00930	COG1477	protein flavinylation
KBQ49_00955	COG4774	siderophore transport
KBQ49_00960	COG2146	nitrite reductase [NAD(P)H] activity
KBQ49_00970	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KBQ49_00975	COG0719	Fe-S assembly protein
KBQ49_00980	COG0396	ATPase activity
KBQ49_00985	COG0719	Fe-S assembly protein
KBQ49_01000	COG0693	protein deglycase activity
KBQ49_01015	COG0739	heme binding
KBQ49_01030	COG1764	response to oxidative stress
KBQ49_01040	COG0384	phenazine biosynthesis protein PhzF
KBQ49_01045	COG0527	aspartate kinase activity
KBQ49_01070	COG0142	geranyltranstransferase activity
KBQ49_01075	COG0629	single-stranded DNA binding
KBQ49_01080	COG3550	peptidyl-serine autophosphorylation
KBQ49_01095	COG3104	oligopeptide transport
KBQ49_01100	COG1297	OPT oligopeptide transporter protein
KBQ49_01105	COG0823	Involved in the tonB-independent uptake of proteins
KBQ49_01105	COG1506	peptidase
KBQ49_01125	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KBQ49_01130	COG2879	small protein
KBQ49_01135	COG1966	Carbon starvation protein
KBQ49_01170	COG2211	Major facilitator Superfamily
KBQ49_01205	COG0835	chemotaxis
KBQ49_01210	COG0840	transmembrane signaling receptor activity
KBQ49_01215	COG0840	transmembrane signaling receptor activity
KBQ49_01220	COG0840	transmembrane signaling receptor activity
KBQ49_01225	COG0643	Histidine kinase
KBQ49_01225	COG2198	Histidine kinase
KBQ49_01250	COG3878	Protein conserved in bacteria
KBQ49_01255	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
KBQ49_01265	COG2205	protein histidine kinase activity
KBQ49_01305	COG0735	belongs to the Fur family
KBQ49_01340	COG1529	Aldehyde oxidase and xanthine dehydrogenase
KBQ49_01345	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
KBQ49_01350	COG2080	2 iron, 2 sulfur cluster binding
KBQ49_01450	COG1187	pseudouridine synthase activity
KBQ49_01475	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KBQ49_01495	COG1132	(ABC) transporter
KBQ49_01515	COG0583	DNA-binding transcription factor activity
KBQ49_01555	COG1981	membrane
KBQ49_01580	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KBQ49_01585	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KBQ49_01595	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KBQ49_01600	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KBQ49_01605	COG0750	zinc metalloprotease
KBQ49_01610	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
KBQ49_01615	COG0575	Belongs to the CDS family
KBQ49_01620	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KBQ49_01630	COG0528	UMP kinase activity
KBQ49_01640	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KBQ49_01680	COG0024	Methionine aminopeptidase
KBQ49_01695	COG1393	Belongs to the ArsC family
KBQ49_01700	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KBQ49_01710	COG0367	asparagine synthase
KBQ49_01745	COG1566	PFAM secretion protein HlyD family protein
KBQ49_01750	COG2814	Major facilitator Superfamily
KBQ49_01785	COG0557	exoribonuclease II activity
KBQ49_01795	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KBQ49_01805	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KBQ49_01825	COG0704	Plays a role in the regulation of phosphate uptake
KBQ49_01835	COG0581	inorganic phosphate transmembrane transporter activity
KBQ49_01845	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KBQ49_01850	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KBQ49_01875	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KBQ49_01885	COG1024	Enoyl-CoA hydratase
KBQ49_01950	COG0784	Response regulator, receiver
KBQ49_01950	COG2205	protein histidine kinase activity
KBQ49_01950	COG5002	protein histidine kinase activity
KBQ49_01955	COG2733	membrane
KBQ49_01975	COG0686	Belongs to the AlaDH PNT family
KBQ49_01980	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KBQ49_01985	COG1396	sequence-specific DNA binding
KBQ49_01985	COG1917	Cupin 2, conserved barrel domain protein
KBQ49_01990	COG1012	belongs to the aldehyde dehydrogenase family
KBQ49_02010	COG2223	nitrite transmembrane transporter activity
KBQ49_02020	COG0243	molybdopterin cofactor binding
KBQ49_02045	COG0477	Major facilitator Superfamily
KBQ49_02055	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KBQ49_02060	COG0174	glutamine synthetase
KBQ49_02065	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
KBQ49_02070	COG0174	glutamine synthetase
KBQ49_02080	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
KBQ49_02085	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
KBQ49_02105	COG3842	ATPase activity
KBQ49_02110	COG1176	ABC-type spermidine putrescine transport system, permease component I
KBQ49_02115	COG1177	transmembrane transport
KBQ49_02120	COG1012	belongs to the aldehyde dehydrogenase family
KBQ49_02135	COG4535	Mg2 and Co2 transporter CorC
KBQ49_02150	COG1702	phosphate starvation-inducible protein PhoH
KBQ49_02165	COG0741	lytic transglycosylase activity
KBQ49_02170	COG0723	plastoquinol--plastocyanin reductase activity
KBQ49_02175	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KBQ49_02185	COG2857	Cytochrome c1
KBQ49_02190	COG0625	glutathione transferase activity
KBQ49_02195	COG2969	positive regulation of protein catabolic process
KBQ49_02235	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
KBQ49_02240	COG1028	Short-chain dehydrogenase reductase Sdr
KBQ49_02245	COG2095	MarC family integral membrane protein
KBQ49_02255	COG1611	Belongs to the LOG family
KBQ49_02260	COG3275	phosphorelay sensor kinase activity
KBQ49_02305	COG0556	nucleotide-excision repair
KBQ49_02415	COG2948	multi-organism process
KBQ49_02530	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KBQ49_02540	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KBQ49_02545	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KBQ49_02595	COG0438	transferase activity, transferring glycosyl groups
KBQ49_02600	COG0438	transferase activity, transferring glycosyl groups
KBQ49_02610	COG0438	transferase activity, transferring glycosyl groups
KBQ49_02630	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KBQ49_02640	COG1960	acyl-CoA dehydrogenase activity
KBQ49_02675	COG1570	exodeoxyribonuclease VII activity
KBQ49_02680	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KBQ49_02685	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KBQ49_02685	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
KBQ49_02690	COG0802	atpase or kinase
KBQ49_02695	COG0860	N-Acetylmuramoyl-L-alanine amidase
KBQ49_02700	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KBQ49_02720	COG1028	Short-chain dehydrogenase reductase Sdr
KBQ49_02740	COG2081	HI0933 family
KBQ49_02745	COG4681	YaeQ
KBQ49_02750	COG0564	pseudouridine synthase activity
KBQ49_02760	COG0625	glutathione transferase activity
KBQ49_02765	COG0657	acetylesterase activity
KBQ49_02770	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
KBQ49_02795	COG0513	Belongs to the DEAD box helicase family
KBQ49_02800	COG0488	(ABC) transporter
KBQ49_02820	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KBQ49_02830	COG1472	Belongs to the glycosyl hydrolase 3 family
KBQ49_02870	COG1846	Transcriptional regulator
KBQ49_02885	COG0386	Belongs to the glutathione peroxidase family
KBQ49_02960	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KBQ49_02965	COG0084	hydrolase, TatD family'
KBQ49_02980	COG1960	acyl-CoA dehydrogenase activity
KBQ49_02990	COG0305	Participates in initiation and elongation during chromosome replication
KBQ49_02995	COG0415	Belongs to the DNA photolyase family
KBQ49_03010	COG0583	DNA-binding transcription factor activity
KBQ49_03025	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KBQ49_03060	COG1404	Belongs to the peptidase S8 family
KBQ49_03065	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
KBQ49_03070	COG2867	negative regulation of translational initiation
KBQ49_03080	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KBQ49_03085	COG0735	belongs to the Fur family
KBQ49_03090	COG0497	DNA recombination
KBQ49_03095	COG1420	regulation of RNA biosynthetic process
KBQ49_03100	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KBQ49_03105	COG0443	Heat shock 70 kDa protein
KBQ49_03110	COG0484	heat shock protein binding
KBQ49_03115	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
KBQ49_03120	COG0287	Prephenate dehydrogenase
KBQ49_03120	COG1605	Chorismate mutase
KBQ49_03130	COG1132	(ABC) transporter
KBQ49_03180	COG0567	Dehydrogenase, E1 component
KBQ49_03190	COG2850	peptidyl-arginine hydroxylation
KBQ49_03245	COG1131	(ABC) transporter
KBQ49_03250	COG1725	Transcriptional regulator
KBQ49_03260	COG0386	Belongs to the glutathione peroxidase family
KBQ49_03275	COG2900	Belongs to the SlyX family
KBQ49_03285	COG2755	lipolytic protein G-D-S-L family
KBQ49_03285	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
KBQ49_03295	COG1410	methionine synthase
KBQ49_03295	COG0646	methionine synthase
KBQ49_03300	COG1410	methionine synthase
KBQ49_03300	COG0646	methionine synthase
KBQ49_03305	COG2226	methyltransferase
KBQ49_03310	COG1960	acyl-CoA dehydrogenase activity
KBQ49_03355	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KBQ49_03365	COG2902	Dehydrogenase
KBQ49_03415	COG2925	Exonuclease
KBQ49_03425	COG3844	kynureninase activity
KBQ49_03440	COG0288	reversible hydration of carbon dioxide
KBQ49_03510	COG0316	Belongs to the HesB IscA family
KBQ49_03545	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KBQ49_03555	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
KBQ49_03565	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
KBQ49_03600	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
KBQ49_03615	COG1228	amidohydrolase
KBQ49_03630	COG4221	oxidoreductase activity
KBQ49_03670	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KBQ49_03675	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KBQ49_03680	COG0077	Prephenate dehydratase
KBQ49_03680	COG1605	Chorismate mutase
KBQ49_03705	COG0583	DNA-binding transcription factor activity
KBQ49_03745	COG0577	efflux transmembrane transporter activity
KBQ49_03745	COG1136	(ABC) transporter
KBQ49_03775	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KBQ49_03775	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KBQ49_03780	COG1105	Belongs to the carbohydrate kinase PfkB family
KBQ49_03785	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KBQ49_03785	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
KBQ49_03790	COG1609	Transcriptional regulator
KBQ49_03800	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
KBQ49_03840	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KBQ49_03855	COG1253	flavin adenine dinucleotide binding
KBQ49_03865	COG0306	phosphate transporter
KBQ49_03890	COG0504	CTP synthase activity
KBQ49_03905	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
KBQ49_03910	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
KBQ49_03915	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
KBQ49_03930	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
KBQ49_03940	COG1238	metal cluster binding
KBQ49_03955	COG1534	Rna-binding protein
KBQ49_03960	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
KBQ49_03965	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KBQ49_03975	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KBQ49_03980	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KBQ49_03990	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KBQ49_03995	COG1546	Belongs to the CinA family
KBQ49_04000	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
KBQ49_04005	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KBQ49_04010	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KBQ49_04015	COG2137	regulation of response to DNA damage stimulus
KBQ49_04075	COG1294	oxidase, subunit
KBQ49_04085	COG4988	ABC transporter
KBQ49_04090	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KBQ49_04095	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KBQ49_04145	COG4133	protoheme IX ABC transporter activity
KBQ49_04150	COG0436	Aminotransferase
KBQ49_04175	COG1187	pseudouridine synthase activity
KBQ49_04180	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KBQ49_04185	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KBQ49_04190	COG2350	Protein conserved in bacteria
KBQ49_04225	COG0395	ABC-type sugar transport system, permease component
KBQ49_04240	COG0129	dihydroxy-acid dehydratase activity
KBQ49_04255	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KBQ49_04260	COG3842	ATPase activity
KBQ49_04275	COG2009	succinate dehydrogenase
KBQ49_04280	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
KBQ49_04295	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
KBQ49_04305	COG4591	ABC-type transport system involved in lipoprotein release permease component
KBQ49_04325	COG0811	peptide transport
KBQ49_04335	COG1132	(ABC) transporter
KBQ49_04340	COG1663	tetraacyldisaccharide 4'-kinase activity
KBQ49_04350	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KBQ49_04365	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KBQ49_04375	COG0582	viral genome integration into host DNA
KBQ49_04380	COG0583	DNA-binding transcription factor activity
KBQ49_04585	COG0515	serine threonine protein kinase
KBQ49_04585	COG2815	serine threonine protein kinase
KBQ49_04595	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KBQ49_04720	COG0270	DNA (cytosine-5-)-methyltransferase activity
KBQ49_04725	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KBQ49_04730	COG0629	single-stranded DNA binding
KBQ49_04775	COG2207	Transcriptional regulator
KBQ49_04825	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
KBQ49_04830	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KBQ49_04840	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KBQ49_04865	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KBQ49_04870	COG2258	MOSC domain
KBQ49_04880	COG0505	Belongs to the CarA family
KBQ49_04890	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
KBQ49_04895	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KBQ49_04905	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KBQ49_04990	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
KBQ49_05010	COG1024	Enoyl-CoA hydratase
KBQ49_05020	COG1024	Enoyl-CoA hydratase
KBQ49_05025	COG1024	Enoyl-CoA hydratase
KBQ49_05065	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KBQ49_05080	COG0346	lactoylglutathione lyase activity
KBQ49_05090	COG1304	FMN binding
KBQ49_05095	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KBQ49_05100	COG1649	PFAM Uncharacterised BCR, COG1649
KBQ49_05170	COG2205	protein histidine kinase activity
KBQ49_05170	COG0784	Response regulator, receiver
KBQ49_05175	COG2183	response to ionizing radiation
KBQ49_05180	COG4191	Histidine kinase
KBQ49_05180	COG0784	Response regulator, receiver
KBQ49_05190	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KBQ49_05190	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
KBQ49_05210	COG3243	poly(R)-hydroxyalkanoic acid synthase
KBQ49_05220	COG1183	phosphatidylcholine synthase activity
KBQ49_05225	COG1028	Short-chain dehydrogenase reductase Sdr
KBQ49_05240	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
KBQ49_05250	COG0668	transmembrane transport
KBQ49_05255	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
KBQ49_05270	COG1914	H( )-stimulated, divalent metal cation uptake system
KBQ49_05280	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
KBQ49_05345	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KBQ49_05345	COG0519	Catalyzes the synthesis of GMP from XMP
KBQ49_05355	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KBQ49_05370	COG0475	glutathione-regulated potassium exporter activity
KBQ49_05370	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KBQ49_05375	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KBQ49_05385	COG0746	molybdenum cofactor guanylyltransferase activity
KBQ49_05395	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KBQ49_05405	COG1426	Protein conserved in bacteria
KBQ49_05415	COG0820	rRNA (adenine-C2-)-methyltransferase activity
KBQ49_05430	COG1024	Enoyl-CoA hydratase
KBQ49_05430	COG1250	3-hydroxyacyl-CoA dehydrogenase
KBQ49_05435	COG0183	Belongs to the thiolase family
KBQ49_05440	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KBQ49_05450	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KBQ49_05455	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
KBQ49_05465	COG0776	regulation of translation
KBQ49_05470	COG0539	negative regulation of cytoplasmic translation
KBQ49_05475	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
KBQ49_05480	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KBQ49_05490	COG2957	Belongs to the agmatine deiminase family
KBQ49_05495	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KBQ49_05515	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KBQ49_05535	COG0316	Belongs to the HesB IscA family
KBQ49_05535	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
KBQ49_05550	COG0428	transporter
KBQ49_05565	COG1530	ribonuclease E activity
KBQ49_05590	COG2801	Transposase and inactivated derivatives
KBQ49_05635	COG1022	Amp-dependent synthetase and ligase
KBQ49_05640	COG2801	Transposase and inactivated derivatives
KBQ49_05670	COG1132	(ABC) transporter
KBQ49_05690	COG0438	transferase activity, transferring glycosyl groups
KBQ49_05695	COG0438	transferase activity, transferring glycosyl groups
KBQ49_05715	COG4106	trans-aconitate 2-methyltransferase activity
KBQ49_05735	COG2244	polysaccharide biosynthetic process
KBQ49_05765	COG3038	cytochrome b561
KBQ49_05785	COG1595	DNA-templated transcription, initiation
KBQ49_05840	COG0038	chloride channel
KBQ49_05845	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KBQ49_05865	COG1674	ftsk spoiiie
KBQ49_05870	COG0492	ferredoxin-NADP+ reductase activity
KBQ49_05890	COG0542	response to heat
KBQ49_05910	COG0482	sulfurtransferase activity
KBQ49_05915	COG2915	High frequency lysogenization protein hflD homolog
KBQ49_05975	COG0784	Response regulator, receiver
KBQ49_05975	COG0835	chemotaxis
KBQ49_05985	COG1558	bacterial-type flagellum-dependent cell motility
KBQ49_05995	COG1749	Flagellar hook protein flgE
KBQ49_06010	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
KBQ49_06025	COG4786	Flagellar basal body rod
KBQ49_06025	COG1256	bacterial-type flagellum assembly
KBQ49_06025	COG1256	bacterial-type flagellum assembly
KBQ49_06025	COG4786	Flagellar basal body rod
KBQ49_06030	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KBQ49_06035	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KBQ49_06040	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
KBQ49_06060	COG2197	response regulator
KBQ49_06065	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
KBQ49_06070	COG2201	protein-glutamate methylesterase activity
KBQ49_06090	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KBQ49_06095	COG1028	Short-chain dehydrogenase reductase Sdr
KBQ49_06100	COG1028	Short-chain dehydrogenase reductase Sdr
KBQ49_06150	COG1677	Flagellar hook-basal body complex protein FliE
KBQ49_06200	COG3190	flagellar
KBQ49_06210	COG1987	bacterial-type flagellum assembly
KBQ49_06215	COG1684	flagellar biosynthetic protein fliR
KBQ49_06260	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
KBQ49_06265	COG0643	Histidine kinase
KBQ49_06265	COG0784	Response regulator, receiver
KBQ49_06265	COG2198	Histidine kinase
KBQ49_06270	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KBQ49_06280	COG1192	Involved in chromosome partitioning
KBQ49_06285	COG0835	chemotaxis
KBQ49_06295	COG0745	RESPONSE REGULATOR receiver
KBQ49_06310	COG0840	transmembrane signaling receptor activity
KBQ49_06315	COG0840	transmembrane signaling receptor activity
KBQ49_06320	COG0840	transmembrane signaling receptor activity
KBQ49_06325	COG0840	transmembrane signaling receptor activity
KBQ49_06335	COG0840	transmembrane signaling receptor activity
KBQ49_06345	COG0840	transmembrane signaling receptor activity
KBQ49_06350	COG0840	transmembrane signaling receptor activity
KBQ49_06355	COG0840	transmembrane signaling receptor activity
KBQ49_06365	COG0840	transmembrane signaling receptor activity
KBQ49_06375	COG0835	chemotaxis
KBQ49_06385	COG0840	transmembrane signaling receptor activity
KBQ49_06395	COG0840	transmembrane signaling receptor activity
KBQ49_06420	COG3706	GGDEF domain
KBQ49_06450	COG0318	PFAM AMP-dependent synthetase and ligase
KBQ49_06455	COG1024	Enoyl-CoA hydratase
KBQ49_06460	COG2198	Histidine kinase
KBQ49_06460	COG0784	Response regulator, receiver
KBQ49_06460	COG2205	protein histidine kinase activity
KBQ49_06495	COG0800	Aldolase
KBQ49_06510	COG3734	2-keto-3-deoxy-galactonokinase
KBQ49_06515	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
KBQ49_06525	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KBQ49_06535	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KBQ49_06540	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
KBQ49_06555	COG0351	phosphomethylpyrimidine kinase
KBQ49_06575	COG0583	DNA-binding transcription factor activity
KBQ49_06580	COG1741	Belongs to the pirin family
KBQ49_06625	COG1024	Enoyl-CoA hydratase
KBQ49_06640	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KBQ49_06660	COG0277	FAD linked oxidase domain protein
KBQ49_06665	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KBQ49_06680	COG0531	amino acid
KBQ49_06685	COG0531	amino acid
KBQ49_06695	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
KBQ49_06700	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
KBQ49_06720	COG0140	phosphoribosyl-ATP diphosphatase activity
KBQ49_06720	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KBQ49_06735	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KBQ49_06745	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KBQ49_06750	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KBQ49_06755	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
KBQ49_06765	COG0124	histidyl-tRNA synthetase
KBQ49_06770	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KBQ49_06780	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KBQ49_06790	COG2951	lytic endotransglycosylase activity
KBQ49_06800	COG0460	homoserine dehydrogenase
KBQ49_06800	COG0527	aspartate kinase activity
KBQ49_06815	COG1012	belongs to the aldehyde dehydrogenase family
KBQ49_06830	COG0167	dihydroorotate dehydrogenase activity
KBQ49_06835	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KBQ49_06865	COG0671	phosphoesterase, PA-phosphatase related
KBQ49_06880	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
KBQ49_06915	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
KBQ49_06925	COG0617	tRNA 3'-terminal CCA addition
KBQ49_06945	COG0860	N-Acetylmuramoyl-L-alanine amidase
KBQ49_06950	COG0477	Major facilitator Superfamily
KBQ49_06955	COG2115	Belongs to the xylose isomerase family
KBQ49_06960	COG1070	Carbohydrate kinase
KBQ49_06970	COG1501	Belongs to the glycosyl hydrolase 31 family
KBQ49_06995	COG2801	Transposase and inactivated derivatives
KBQ49_07005	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KBQ49_07025	COG0165	Argininosuccinate lyase
KBQ49_07030	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KBQ49_07040	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
KBQ49_07045	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KBQ49_07050	COG0137	argininosuccinate synthase activity
KBQ49_07055	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KBQ49_07070	COG2166	iron-sulfur cluster assembly
KBQ49_07100	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
KBQ49_07115	COG4677	pectinesterase activity
KBQ49_07145	COG0402	S-adenosylhomocysteine deaminase activity
KBQ49_07150	COG3548	integral membrane protein
KBQ49_07160	COG1509	lysine 2,3-aminomutase activity
KBQ49_07165	COG2203	Gaf domain
KBQ49_07165	COG3706	GGDEF domain
KBQ49_07165	COG4251	negative regulation of phosphorylation
KBQ49_07165	COG5001	Diguanylate cyclase
KBQ49_07195	COG1862	Preprotein translocase
KBQ49_07205	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KBQ49_07215	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KBQ49_07225	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KBQ49_07230	COG3291	Pkd domain containing protein
KBQ49_07235	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KBQ49_07240	COG0405	Gamma-glutamyltransferase
KBQ49_07245	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
KBQ49_07260	COG0742	ribosomal rna small subunit methyltransferase
KBQ49_07285	COG4771	TonB-dependent receptor
KBQ49_07295	COG3507	Belongs to the glycosyl hydrolase 43 family
KBQ49_07305	COG4206	TonB-dependent receptor
KBQ49_07330	COG0531	amino acid
KBQ49_07345	COG0006	proline dipeptidase activity
KBQ49_07355	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KBQ49_07370	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KBQ49_07375	COG3938	Belongs to the proline racemase family
KBQ49_07385	COG0552	protein localization to endoplasmic reticulum
KBQ49_07435	COG0835	chemotaxis
KBQ49_07440	COG0840	transmembrane signaling receptor activity
KBQ49_07445	COG0840	transmembrane signaling receptor activity
KBQ49_07465	COG3300	MHYT domain
KBQ49_07465	COG5001	Diguanylate cyclase
KBQ49_07475	COG1185	polyribonucleotide nucleotidyltransferase activity
KBQ49_07500	COG0195	Participates in both transcription termination and antitermination
KBQ49_07515	COG1007	ATP synthesis coupled electron transport
KBQ49_07555	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
KBQ49_07560	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
KBQ49_07565	COG0649	NAD binding
KBQ49_07570	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KBQ49_07580	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KBQ49_07610	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KBQ49_07670	COG2890	protein-(glutamine-N5) methyltransferase activity
KBQ49_07680	COG0688	phosphatidylethanolamine metabolic process
KBQ49_07685	COG0741	lytic transglycosylase activity
KBQ49_07690	COG0433	COG0433 Predicted ATPase
KBQ49_07695	COG0494	nUDIX hydrolase
KBQ49_07710	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KBQ49_07730	COG1714	RDD family
KBQ49_07735	COG0717	Belongs to the dCTP deaminase family
KBQ49_07740	COG0489	protein tyrosine kinase activity
KBQ49_07750	COG4771	TonB-dependent receptor
KBQ49_07760	COG4771	TonB-dependent receptor
KBQ49_07765	COG0457	Tetratricopeptide repeat
KBQ49_07780	COG3590	peptidase
KBQ49_07820	COG0697	spore germination
KBQ49_07840	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KBQ49_07845	COG2311	Membrane
KBQ49_07850	COG1047	Peptidyl-prolyl cis-trans
KBQ49_07855	COG0791	NLP P60 protein
KBQ49_07860	COG0791	NLP P60 protein
KBQ49_07875	COG1607	acyl-coa hydrolase
KBQ49_07885	COG1301	dicarboxylic acid transport
KBQ49_07890	COG1785	Belongs to the alkaline phosphatase family
KBQ49_07900	COG0037	tRNA processing
KBQ49_07905	COG1722	exodeoxyribonuclease VII activity
KBQ49_07910	COG0142	geranyltranstransferase activity
KBQ49_07920	COG1858	cytochrome C peroxidase
KBQ49_07945	COG2815	serine threonine protein kinase
KBQ49_07945	COG0515	serine threonine protein kinase
KBQ49_07950	COG0631	protein serine/threonine phosphatase activity
KBQ49_08045	COG0312	modulator of DNA gyrase
KBQ49_08055	COG0312	modulator of DNA gyrase
KBQ49_08075	COG2968	Membrane
KBQ49_08090	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KBQ49_08105	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KBQ49_08120	COG0495	leucyl-tRNA aminoacylation
KBQ49_08130	COG3118	belongs to the thioredoxin family
KBQ49_08145	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
KBQ49_08155	COG2040	homocysteine
KBQ49_08160	COG0833	amino acid
KBQ49_08170	COG0346	lactoylglutathione lyase activity
KBQ49_08190	COG2878	Part of a membrane complex involved in electron transport
KBQ49_08205	COG1595	DNA-templated transcription, initiation
KBQ49_08230	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KBQ49_08250	COG0251	oxidation-reduction process
KBQ49_08260	COG0392	lysyltransferase activity
KBQ49_08260	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KBQ49_08290	COG2814	Major facilitator Superfamily
KBQ49_08295	COG1902	pentaerythritol trinitrate reductase activity
KBQ49_08300	COG2824	Alkylphosphonate utilization operon protein PhnA
KBQ49_08305	COG1047	Peptidyl-prolyl cis-trans
KBQ49_08310	COG1077	Cell shape determining protein MreB Mrl
KBQ49_08345	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KBQ49_08355	COG1451	nucleotide metabolic process
KBQ49_08375	COG2198	Histidine kinase
KBQ49_08375	COG2205	protein histidine kinase activity
KBQ49_08375	COG0784	Response regulator, receiver
KBQ49_08385	COG2186	Transcriptional regulator
KBQ49_08390	COG3250	beta-galactosidase activity
KBQ49_08455	COG1703	isobutyryl-CoA mutase activity
KBQ49_08455	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
KBQ49_08455	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
KBQ49_08485	COG0183	Belongs to the thiolase family
KBQ49_08495	COG0443	Heat shock 70 kDa protein
KBQ49_08525	COG1793	dna ligase
KBQ49_08525	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
KBQ49_08530	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
KBQ49_08530	COG1793	dna ligase
KBQ49_08535	COG1201	RNA secondary structure unwinding
KBQ49_08545	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KBQ49_08550	COG1278	Cold shock
KBQ49_08555	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
KBQ49_08560	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
KBQ49_08565	COG1472	Belongs to the glycosyl hydrolase 3 family
KBQ49_08575	COG2954	triphosphatase activity
KBQ49_08585	COG0745	RESPONSE REGULATOR receiver
KBQ49_08590	COG1381	Involved in DNA repair and RecF pathway recombination
KBQ49_08595	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KBQ49_08610	COG0681	Belongs to the peptidase S26 family
KBQ49_08615	COG0481	GTPase activity
KBQ49_08620	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KBQ49_08635	COG1024	Enoyl-CoA hydratase
KBQ49_08635	COG1250	3-hydroxyacyl-CoA dehydrogenase
KBQ49_08655	COG2855	membrane
KBQ49_08670	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KBQ49_08690	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
KBQ49_08700	COG0534	Mate efflux family protein
KBQ49_08705	COG0335	large ribosomal subunit rRNA binding
KBQ49_08710	COG0336	Belongs to the RNA methyltransferase TrmD family
KBQ49_08715	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KBQ49_08720	COG0228	four-way junction DNA binding
KBQ49_08730	COG2070	2-Nitropropane dioxygenase
KBQ49_08735	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KBQ49_08760	COG0475	glutathione-regulated potassium exporter activity
KBQ49_08770	COG0625	glutathione transferase activity
KBQ49_08775	COG1082	Xylose isomerase domain protein TIM barrel
KBQ49_08785	COG1172	Belongs to the binding-protein-dependent transport system permease family
KBQ49_08790	COG1172	Belongs to the binding-protein-dependent transport system permease family
KBQ49_08795	COG1129	ABC transporter
KBQ49_08800	COG1879	ABC-type sugar transport system periplasmic component
KBQ49_08805	COG1012	belongs to the aldehyde dehydrogenase family
KBQ49_08825	COG0129	dihydroxy-acid dehydratase activity
KBQ49_08855	COG2207	Transcriptional regulator
KBQ49_08900	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KBQ49_08925	COG4794	Type iii secretion
KBQ49_08955	COG0745	RESPONSE REGULATOR receiver
KBQ49_08980	COG1595	DNA-templated transcription, initiation
KBQ49_09010	COG0156	8-amino-7-oxononanoate synthase activity
KBQ49_09020	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
KBQ49_09025	COG1845	cytochrome c oxidase, subunit III
KBQ49_09030	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KBQ49_09055	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
KBQ49_09070	COG0196	riboflavin kinase activity
KBQ49_09085	COG0728	peptidoglycan biosynthetic process
KBQ49_09095	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KBQ49_09100	COG0211	Belongs to the bacterial ribosomal protein bL27 family
KBQ49_09105	COG0261	This protein binds to 23S rRNA in the presence of protein L20
KBQ49_09110	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KBQ49_09115	COG0824	Thioesterase
KBQ49_09125	COG1024	Enoyl-CoA hydratase
KBQ49_09130	COG1946	Acyl-CoA thioesterase
KBQ49_09145	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
KBQ49_09185	COG1073	alpha beta
KBQ49_09210	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KBQ49_09255	COG1643	Atp-dependent helicase
KBQ49_09260	COG0783	Belongs to the Dps family
KBQ49_09265	COG0514	ATP-dependent DNA helicase (RecQ)
KBQ49_09285	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KBQ49_09290	COG0602	queuosine metabolic process
KBQ49_09300	COG2885	chlorophyll binding
KBQ49_09315	COG0848	biopolymer transport protein
KBQ49_09325	COG0824	Thioesterase
KBQ49_09330	COG2255	four-way junction helicase activity
KBQ49_09335	COG3158	transport of potassium into the cell
KBQ49_09340	COG0632	four-way junction helicase activity
KBQ49_09350	COG0217	transcriptional regulatory protein
KBQ49_09390	COG3142	Participates in the control of copper homeostasis
KBQ49_09395	COG1446	asparaginase
KBQ49_09445	COG2201	protein-glutamate methylesterase activity
KBQ49_09450	COG2198	Histidine kinase
KBQ49_09450	COG0784	Response regulator, receiver
KBQ49_09450	COG0643	Histidine kinase
KBQ49_09455	COG0840	transmembrane signaling receptor activity
KBQ49_09460	COG0835	chemotaxis
KBQ49_09475	COG0189	ligase activity
KBQ49_09495	COG1199	ATP-dependent helicase activity
KBQ49_09505	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KBQ49_09510	COG1216	Glycosyl transferase, family 2
KBQ49_09515	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KBQ49_09535	COG4585	Histidine kinase
KBQ49_09545	COG0850	regulation of cytokinetic process
KBQ49_09550	COG2894	cell division
KBQ49_09555	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
KBQ49_09565	COG2205	protein histidine kinase activity
KBQ49_09570	COG0745	RESPONSE REGULATOR receiver
KBQ49_09580	COG2194	sulfuric ester hydrolase activity
KBQ49_09675	COG2814	Major facilitator Superfamily
KBQ49_09700	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KBQ49_09700	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KBQ49_09715	COG0753	catalase activity
KBQ49_09740	COG1063	alcohol dehydrogenase
KBQ49_09750	COG3459	Glycosyltransferase 36 associated
KBQ49_09860	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
KBQ49_09890	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KBQ49_09900	COG0330	HflC and HflK could
KBQ49_09905	COG0330	HflC and HflK could
KBQ49_09910	COG0604	alcohol dehydrogenase
KBQ49_09935	COG0678	peroxiredoxin activity
KBQ49_09945	COG4953	penicillin-binding protein 1C
KBQ49_09965	COG2373	Large extracellular alpha-helical protein
KBQ49_10015	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KBQ49_10030	COG0372	Belongs to the citrate synthase family
KBQ49_10055	COG2161	toxin-antitoxin pair type II binding
KBQ49_10060	COG4115	mRNA cleavage
KBQ49_10080	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KBQ49_10085	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KBQ49_10090	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KBQ49_10100	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KBQ49_10105	COG1028	Short-chain dehydrogenase reductase Sdr
KBQ49_10110	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KBQ49_10115	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KBQ49_10125	COG1399	metal-binding, possibly nucleic acid-binding protein
KBQ49_10150	COG0714	Associated with various cellular activities
KBQ49_10170	COG0537	adenosine 5'-monophosphoramidase activity
KBQ49_10200	COG0314	molybdopterin synthase activity
KBQ49_10205	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
KBQ49_10210	COG0315	cyclic pyranopterin monophosphate synthase activity
KBQ49_10220	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KBQ49_10225	COG1234	tRNA 3'-trailer cleavage
KBQ49_10235	COG0859	PFAM glycosyl transferase family 9
KBQ49_10255	COG0631	protein serine/threonine phosphatase activity
KBQ49_10260	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KBQ49_10265	COG0328	RNA-DNA hybrid ribonuclease activity
KBQ49_10275	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KBQ49_10280	COG3942	CHAP domain
KBQ49_10280	COG1388	LysM domain
KBQ49_10320	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KBQ49_10330	COG0544	peptidyl-prolyl cis-trans isomerase activity
KBQ49_10375	COG0473	3-isopropylmalate dehydrogenase activity
KBQ49_10390	COG4783	chaperone-mediated protein folding
KBQ49_10405	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KBQ49_10410	COG0248	Ppx GppA phosphatase
KBQ49_10415	COG0438	transferase activity, transferring glycosyl groups
KBQ49_10425	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KBQ49_10435	COG3291	Pkd domain containing protein
KBQ49_10460	COG0285	dihydrofolate synthase activity
KBQ49_10465	COG0588	phosphoglycerate mutase activity
KBQ49_10485	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
KBQ49_10490	COG4208	sulfate ABC transporter
KBQ49_10495	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
KBQ49_10500	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
KBQ49_10505	COG0156	8-amino-7-oxononanoate synthase activity
KBQ49_10525	COG2885	chlorophyll binding
KBQ49_10545	COG0667	Aldo Keto reductase
KBQ49_10560	COG0446	pyridine nucleotide-disulphide oxidoreductase
KBQ49_10560	COG1902	pentaerythritol trinitrate reductase activity
KBQ49_10605	COG0625	glutathione transferase activity
KBQ49_10610	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KBQ49_10620	COG0039	L-malate dehydrogenase activity
KBQ49_10630	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KBQ49_10635	COG1217	gtp-binding protein TYPA
KBQ49_10650	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
KBQ49_10660	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
KBQ49_10665	COG0203	ribosomal protein L17
KBQ49_10690	COG0201	protein transport
KBQ49_10700	COG1841	ribosomal large subunit assembly
KBQ49_10725	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KBQ49_10730	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KBQ49_10735	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KBQ49_10745	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KBQ49_10750	COG0255	Belongs to the universal ribosomal protein uL29 family
KBQ49_10775	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KBQ49_10780	COG0089	rRNA binding
KBQ49_10785	COG0088	Forms part of the polypeptide exit tunnel
KBQ49_10795	COG0051	transcription antitermination factor activity, RNA binding
KBQ49_10800	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KBQ49_10805	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KBQ49_10820	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KBQ49_10830	COG0222	ribosome binding
KBQ49_10845	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KBQ49_10850	COG0250	Participates in transcription elongation, termination and antitermination
KBQ49_10855	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KBQ49_10865	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KBQ49_10885	COG0012	GTP binding
KBQ49_10890	COG0193	aminoacyl-tRNA hydrolase activity
KBQ49_10900	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KBQ49_10910	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KBQ49_10925	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
KBQ49_10930	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KBQ49_10970	COG0488	(ABC) transporter
KBQ49_11055	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KBQ49_11055	COG4651	solute:proton antiporter activity
KBQ49_11065	COG4772	TonB-dependent receptor
KBQ49_11075	COG4264	IucA IucC family
KBQ49_11080	COG2814	Major facilitator Superfamily
KBQ49_11085	COG4264	IucA IucC family
KBQ49_11090	COG0019	diaminopimelate decarboxylase activity
KBQ49_11115	COG0542	response to heat
KBQ49_11165	COG3387	PFAM Glycoside hydrolase 15-related
KBQ49_11190	COG0564	pseudouridine synthase activity
KBQ49_11195	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KBQ49_11205	COG1125	glycine betaine transport
KBQ49_11210	COG1174	glycine betaine transport
KBQ49_11225	COG1262	PFAM Formylglycine-generating sulfatase enzyme
KBQ49_11235	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KBQ49_11235	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
KBQ49_11275	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KBQ49_11305	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
KBQ49_11320	COG0745	RESPONSE REGULATOR receiver
KBQ49_11330	COG0189	ligase activity
KBQ49_11340	COG3511	phospholipase C
KBQ49_11360	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KBQ49_11375	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
KBQ49_11385	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
KBQ49_11390	COG0174	glutamine synthetase
KBQ49_11415	COG2022	thiamine diphosphate biosynthetic process
KBQ49_11425	COG0471	metal ion transport
KBQ49_11425	COG3273	potassium ion transport
KBQ49_11440	COG0179	Fumarylacetoacetate (FAA) hydrolase
KBQ49_11455	COG1609	Transcriptional regulator
KBQ49_11465	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KBQ49_11505	COG0840	transmembrane signaling receptor activity
KBQ49_11510	COG0529	Catalyzes the synthesis of activated sulfate
KBQ49_11510	COG2895	sulfate adenylyltransferase (ATP) activity
KBQ49_11515	COG0175	sulfate reduction
KBQ49_11520	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KBQ49_11525	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KBQ49_11530	COG0175	sulfate reduction
KBQ49_11560	COG1393	Belongs to the ArsC family
KBQ49_11580	COG1648	precorrin-2 dehydrogenase activity
KBQ49_11580	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KBQ49_11595	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KBQ49_11635	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
KBQ49_11640	COG3588	fructose-bisphosphate aldolase
KBQ49_11645	COG0469	pyruvate kinase activity
KBQ49_11690	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KBQ49_11695	COG3047	cAMP biosynthetic process
KBQ49_11715	COG0640	Transcriptional regulator
KBQ49_11725	COG0725	ABC transporter, periplasmic molybdate-binding protein
KBQ49_11730	COG4149	molybdate abc transporter
KBQ49_11735	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
KBQ49_11760	COG1376	ErfK ybiS ycfS ynhG family protein
KBQ49_11765	COG0739	heme binding
KBQ49_11795	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KBQ49_11800	COG1301	dicarboxylic acid transport
KBQ49_11830	COG0714	Associated with various cellular activities
KBQ49_11860	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
KBQ49_11875	COG0372	Belongs to the citrate synthase family
KBQ49_11880	COG0254	rRNA binding
KBQ49_11890	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KBQ49_11900	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KBQ49_11905	COG1758	RNA polymerase activity
KBQ49_11910	COG0194	GDP metabolic process
KBQ49_11915	COG1561	YicC-like family, N-terminal region
KBQ49_11920	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
KBQ49_11925	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KBQ49_11930	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KBQ49_11960	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KBQ49_12025	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KBQ49_12035	COG0494	nUDIX hydrolase
KBQ49_12085	COG0739	heme binding
KBQ49_12100	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KBQ49_12110	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KBQ49_12115	COG1181	Belongs to the D-alanine--D-alanine ligase family
KBQ49_12125	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KBQ49_12140	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KBQ49_12155	COG3116	cell division
KBQ49_12160	COG0275	rRNA processing
KBQ49_12165	COG2001	Belongs to the MraZ family
KBQ49_12200	COG0792	nuclease activity
KBQ49_12210	COG0277	FAD linked oxidase domain protein
KBQ49_12215	COG0745	RESPONSE REGULATOR receiver
KBQ49_12220	COG2205	protein histidine kinase activity
KBQ49_12230	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
KBQ49_12235	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
KBQ49_12265	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KBQ49_12270	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
KBQ49_12290	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KBQ49_12290	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KBQ49_12300	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KBQ49_12320	COG0488	(ABC) transporter
KBQ49_12325	COG0242	peptide deformylase activity
KBQ49_12355	COG1215	transferase activity, transferring glycosyl groups
KBQ49_12365	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KBQ49_12415	COG2188	Transcriptional regulator
KBQ49_12425	COG1450	Type ii and iii secretion system protein
KBQ49_12440	COG3166	PFAM Fimbrial assembly family protein
KBQ49_12445	COG3156	type II secretion system protein K
KBQ49_12450	COG4795	General secretion pathway protein
KBQ49_12455	COG2165	general secretion pathway protein
KBQ49_12460	COG4970	Tfp pilus assembly protein FimT
KBQ49_12465	COG2165	general secretion pathway protein
KBQ49_12470	COG1459	type II secretion system
KBQ49_12475	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KBQ49_12480	COG1404	Belongs to the peptidase S8 family
KBQ49_12485	COG5295	Hep Hag repeat protein
KBQ49_12495	COG0840	transmembrane signaling receptor activity
KBQ49_12505	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KBQ49_12510	COG4974	Belongs to the 'phage' integrase family
KBQ49_12535	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KBQ49_12565	COG1183	phosphatidylcholine synthase activity
KBQ49_12575	COG0442	prolyl-tRNA aminoacylation
KBQ49_12590	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
KBQ49_12595	COG1127	ABC transporter
KBQ49_12600	COG3218	ABC-type transport auxiliary lipoprotein component
KBQ49_12600	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
KBQ49_12630	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KBQ49_12635	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KBQ49_12640	COG0662	Cupin 2, conserved barrel domain protein
KBQ49_12640	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
KBQ49_12665	COG2086	electron transfer activity
KBQ49_12680	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
KBQ49_12680	COG0546	phosphoglycolate phosphatase activity
KBQ49_12685	COG0277	FAD linked oxidase domain protein
KBQ49_12690	COG0300	oxidoreductase activity
KBQ49_12695	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KBQ49_12760	COG0438	transferase activity, transferring glycosyl groups
KBQ49_12760	COG1216	Glycosyl transferase, family 2
KBQ49_12765	COG0438	transferase activity, transferring glycosyl groups
KBQ49_12765	COG1216	Glycosyl transferase, family 2
KBQ49_12770	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KBQ49_12785	COG0626	cystathionine gamma-synthase activity
KBQ49_12815	COG0625	glutathione transferase activity
KBQ49_12825	COG0513	Belongs to the DEAD box helicase family
KBQ49_12830	COG0720	synthase
KBQ49_12840	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
KBQ49_12845	COG1956	GAF domain-containing protein
KBQ49_12855	COG4206	TonB-dependent receptor
KBQ49_12860	COG0546	phosphoglycolate phosphatase activity
KBQ49_12885	COG0339	signal peptide processing
KBQ49_12890	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KBQ49_12900	COG2217	Heavy metal translocating P-type atpase
KBQ49_12915	COG2132	Multicopper oxidase
KBQ49_12930	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KBQ49_12940	COG1136	(ABC) transporter
KBQ49_12945	COG0577	efflux transmembrane transporter activity
KBQ49_12945	COG1136	(ABC) transporter
KBQ49_12950	COG0577	efflux transmembrane transporter activity
KBQ49_12950	COG1136	(ABC) transporter
KBQ49_12960	COG4191	Histidine kinase
KBQ49_12970	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KBQ49_12990	COG0355	proton-transporting ATP synthase activity, rotational mechanism
KBQ49_13005	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KBQ49_13015	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KBQ49_13025	COG0356	it plays a direct role in the translocation of protons across the membrane
KBQ49_13040	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KBQ49_13045	COG0508	dehydrogenase complex catalyzes the overall conversion of
KBQ49_13080	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KBQ49_13085	COG0697	spore germination
KBQ49_13090	COG1666	GTP binding
KBQ49_13100	COG1187	pseudouridine synthase activity
KBQ49_13125	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KBQ49_13125	COG2205	protein histidine kinase activity
KBQ49_13150	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KBQ49_13210	COG0842	Transport permease protein
KBQ49_13215	COG1131	(ABC) transporter
KBQ49_13220	COG0025	NhaP-type Na H and K H
KBQ49_13230	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
KBQ49_13235	COG1573	uracil-dna glycosylase
KBQ49_13250	COG3384	dioxygenase
KBQ49_13285	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KBQ49_13290	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KBQ49_13310	COG3706	GGDEF domain
KBQ49_13320	COG5001	Diguanylate cyclase
KBQ49_13350	COG4106	trans-aconitate 2-methyltransferase activity
KBQ49_13360	COG2076	Multidrug Resistance protein
KBQ49_13400	COG3275	phosphorelay sensor kinase activity
KBQ49_13405	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
KBQ49_13425	COG0531	amino acid
KBQ49_13435	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
KBQ49_13435	COG5297	Belongs to the glycosyl hydrolase family 6
KBQ49_13450	COG0741	lytic transglycosylase activity
KBQ49_13465	COG2207	Transcriptional regulator
KBQ49_13475	COG0598	Magnesium transport protein CorA
KBQ49_13480	COG1113	amino acid transport
KBQ49_13485	COG0697	spore germination
KBQ49_13510	COG2267	carboxylic ester hydrolase activity
KBQ49_13660	COG0840	transmembrane signaling receptor activity
KBQ49_13675	COG2353	YceI-like domain
KBQ49_13700	COG0584	glycerophosphoryl diester phosphodiesterase
KBQ49_13715	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
KBQ49_13735	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KBQ49_13740	COG0459	protein refolding
KBQ49_13755	COG1324	tolerance protein
KBQ49_13760	COG4232	protein-disulfide reductase activity
KBQ49_13765	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KBQ49_13775	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
KBQ49_13780	COG0511	ligase activity, forming carbon-carbon bonds
KBQ49_13785	COG0439	Biotin carboxylase
KBQ49_13820	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
KBQ49_13825	COG4589	Belongs to the CDS family
KBQ49_13845	COG2267	carboxylic ester hydrolase activity
KBQ49_13850	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KBQ49_13855	COG0138	bifunctional purine biosynthesis protein purh
KBQ49_13860	COG0151	Belongs to the GarS family
KBQ49_13865	COG1289	transmembrane transporter activity
KBQ49_13870	COG2814	Major facilitator Superfamily
KBQ49_13910	COG2816	NAD+ diphosphatase activity
KBQ49_13950	COG2906	2 iron, 2 sulfur cluster binding
KBQ49_13955	COG1051	belongs to the nudix hydrolase family
KBQ49_13980	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
KBQ49_13995	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KBQ49_14000	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KBQ49_14005	COG0730	response to heat
KBQ49_14015	COG0134	indole-3-glycerol-phosphate synthase activity
KBQ49_14020	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KBQ49_14040	COG1597	lipid kinase activity
KBQ49_14055	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
KBQ49_14070	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KBQ49_14075	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KBQ49_14075	COG2111	Na H antiporter
KBQ49_14080	COG1006	Multisubunit Na H antiporter MnhC subunit
KBQ49_14085	COG0651	ATP synthesis coupled electron transport
KBQ49_14090	COG1863	multisubunit Na H antiporter MnhE subunit
KBQ49_14095	COG2212	antiporter activity
KBQ49_14100	COG1320	monovalent cation:proton antiporter activity
KBQ49_14105	COG0530	calcium, potassium:sodium antiporter activity
KBQ49_14120	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
KBQ49_14140	COG3104	oligopeptide transport
KBQ49_14160	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KBQ49_14175	COG0508	dehydrogenase complex catalyzes the overall conversion of
KBQ49_14185	COG3227	Zinc metalloprotease (Elastase)
KBQ49_14190	COG0513	Belongs to the DEAD box helicase family
KBQ49_14225	COG2354	Protein conserved in bacteria
KBQ49_14245	COG1196	nuclear chromosome segregation
KBQ49_14245	COG3264	Mechanosensitive ion channel
KBQ49_14250	COG0604	alcohol dehydrogenase
KBQ49_14250	COG1028	Short-chain dehydrogenase reductase Sdr
KBQ49_14250	COG3321	synthase
KBQ49_14270	COG1595	DNA-templated transcription, initiation
KBQ49_14285	COG1802	Transcriptional regulator
KBQ49_14300	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
KBQ49_14330	COG1414	Transcriptional regulator
KBQ49_14335	COG0738	Major facilitator superfamily
KBQ49_14340	COG3254	rhamnose metabolic process
KBQ49_14350	COG4948	Mandelate Racemase Muconate Lactonizing
KBQ49_14355	COG0179	Fumarylacetoacetate (FAA) hydrolase
KBQ49_14360	COG1028	Short-chain dehydrogenase reductase Sdr
KBQ49_14390	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KBQ49_14405	COG4807	Protein conserved in bacteria
KBQ49_14425	COG4773	Receptor
KBQ49_14440	COG0823	Involved in the tonB-independent uptake of proteins
KBQ49_14440	COG1506	peptidase
KBQ49_14520	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KBQ49_14545	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KBQ49_14550	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KBQ49_14555	COG0753	catalase activity
KBQ49_14580	COG1136	(ABC) transporter
KBQ49_14585	COG0577	efflux transmembrane transporter activity
KBQ49_14605	COG0697	spore germination
KBQ49_14620	COG0180	Tryptophanyl-tRNA synthetase
KBQ49_14655	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
KBQ49_14660	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
KBQ49_14660	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
KBQ49_14670	COG3228	Belongs to the MtfA family
KBQ49_14700	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KBQ49_14725	COG2084	Dehydrogenase
KBQ49_14730	COG1902	pentaerythritol trinitrate reductase activity
KBQ49_14740	COG2814	Major facilitator Superfamily
KBQ49_14745	COG0583	DNA-binding transcription factor activity
KBQ49_14760	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KBQ49_14765	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KBQ49_14775	COG1764	response to oxidative stress
KBQ49_14780	COG1846	Transcriptional regulator
KBQ49_14785	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
KBQ49_14795	COG0697	spore germination
KBQ49_14800	COG0523	cobalamin synthesis protein
KBQ49_14810	COG1742	UPF0060 membrane protein
KBQ49_14820	COG3245	cytochrome
KBQ49_14830	COG1960	acyl-CoA dehydrogenase activity
KBQ49_14835	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KBQ49_14855	COG1278	Cold shock
KBQ49_14870	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KBQ49_14875	COG3387	PFAM Glycoside hydrolase 15-related
KBQ49_14880	COG0745	RESPONSE REGULATOR receiver
KBQ49_14895	COG1404	Belongs to the peptidase S8 family
KBQ49_14905	COG3100	YcgL domain-containing protein
KBQ49_14910	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KBQ49_14920	COG0463	Glycosyl transferase, family 2
KBQ49_14955	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KBQ49_14970	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KBQ49_14995	COG1294	oxidase, subunit
KBQ49_15000	COG1271	oxidase subunit
KBQ49_15020	COG0408	coproporphyrinogen oxidase activity
KBQ49_15030	COG2323	membrane
KBQ49_15035	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KBQ49_15035	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KBQ49_15050	COG0589	response to stress
KBQ49_15075	COG0210	DNA helicase
KBQ49_15125	COG0463	Glycosyl transferase, family 2
KBQ49_15135	COG1475	DNA binding
KBQ49_15140	COG1192	Involved in chromosome partitioning
KBQ49_15145	COG0357	Ribosomal RNA small subunit methyltransferase G
KBQ49_15150	COG2091	lysine biosynthetic process via aminoadipic acid
KBQ49_15175	COG0477	Major facilitator Superfamily
KBQ49_15195	COG1971	Probably functions as a manganese efflux pump
KBQ49_15200	COG2205	protein histidine kinase activity
KBQ49_15210	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KBQ49_15215	COG3459	Glycosyltransferase 36 associated
KBQ49_15220	COG2211	Major facilitator Superfamily
KBQ49_15225	COG3265	gluconokinase activity
KBQ49_15240	COG2911	Protein conserved in bacteria
KBQ49_15245	COG0729	surface antigen
KBQ49_15265	COG3132	Protein of unknown function, DUF480
KBQ49_15295	COG0284	orotidine-5'-phosphate decarboxylase activity
KBQ49_15310	COG1609	Transcriptional regulator
KBQ49_15320	COG2937	Belongs to the GPAT DAPAT family
KBQ49_15345	COG2211	Major facilitator Superfamily
KBQ49_15360	COG3693	PFAM glycoside hydrolase, family 10
KBQ49_15365	COG1904	glucuronate isomerase
KBQ49_15385	COG3046	protein related to deoxyribodipyrimidine photolyase
KBQ49_15400	COG0246	Mannitol dehydrogenase
KBQ49_15405	COG1472	Belongs to the glycosyl hydrolase 3 family
KBQ49_15415	COG4948	Mandelate Racemase Muconate Lactonizing
KBQ49_15425	COG3661	Belongs to the glycosyl hydrolase 67 family
KBQ49_15435	COG2115	Belongs to the xylose isomerase family
KBQ49_15440	COG0037	tRNA processing
KBQ49_15460	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KBQ49_15470	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KBQ49_15480	COG0805	protein transport
KBQ49_15490	COG0519	Catalyzes the synthesis of GMP from XMP
KBQ49_15490	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KBQ49_15495	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KBQ49_15515	COG0210	DNA helicase
KBQ49_15520	COG1435	thymidine kinase activity
KBQ49_15530	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
KBQ49_15545	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
KBQ49_15560	COG1119	ATPase activity
KBQ49_15575	COG0706	membrane insertase activity
KBQ49_15580	COG0594	ribonuclease P activity
KBQ49_15595	COG0592	DNA-directed DNA polymerase activity
KBQ49_15600	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KBQ49_15605	COG0187	DNA topoisomerase II activity
KBQ49_15610	COG1266	CAAX protease self-immunity
KBQ49_15615	COG0501	Belongs to the peptidase M48B family
KBQ49_15655	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KBQ49_15670	COG1280	lysine exporter protein (LysE YggA)
KBQ49_15685	COG4772	TonB-dependent receptor
KBQ49_15695	COG3284	Transcriptional regulator
KBQ49_15700	COG1012	belongs to the aldehyde dehydrogenase family
KBQ49_15735	COG1304	FMN binding
KBQ49_15740	COG2186	Transcriptional regulator
KBQ49_15850	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KBQ49_15870	COG4771	TonB-dependent receptor
KBQ49_15915	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
KBQ49_15930	COG3507	Belongs to the glycosyl hydrolase 43 family
KBQ49_15935	COG1609	Transcriptional regulator
KBQ49_15945	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
KBQ49_15950	COG1028	Short-chain dehydrogenase reductase Sdr
KBQ49_15965	COG3186	Phenylalanine-4-hydroxylase
KBQ49_15970	COG1522	sequence-specific DNA binding
KBQ49_16010	COG1752	Esterase of the alpha-beta hydrolase superfamily
KBQ49_16025	COG0671	phosphoesterase, PA-phosphatase related
KBQ49_16040	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KBQ49_16075	COG1929	Belongs to the glycerate kinase type-1 family
KBQ49_16090	COG4566	intracellular signal transduction
KBQ49_16115	COG1322	Protein conserved in bacteria
KBQ49_16120	COG0386	Belongs to the glutathione peroxidase family
KBQ49_16125	COG2853	Lipoprotein
KBQ49_16140	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
KBQ49_16145	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
KBQ49_16150	COG1127	ABC transporter
KBQ49_16155	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
KBQ49_16160	COG1074	ATP-dependent DNA helicase activity
KBQ49_16165	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KBQ49_16185	COG0537	adenosine 5'-monophosphoramidase activity
KBQ49_16210	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KBQ49_16265	COG0477	Major facilitator Superfamily
KBQ49_16270	COG0302	gtp cyclohydrolase
KBQ49_16295	COG0730	response to heat
KBQ49_16310	COG2951	lytic endotransglycosylase activity
KBQ49_16370	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
KBQ49_16375	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
KBQ49_16380	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
KBQ49_16385	COG0493	'glutamate synthase
KBQ49_16390	COG0067	glutamate synthase
KBQ49_16390	COG0069	glutamate synthase activity
KBQ49_16390	COG0070	glutamate synthase
KBQ49_16435	COG1205	dead DEAH box helicase
KBQ49_16435	COG1111	helicase
KBQ49_16465	COG2271	Major facilitator Superfamily
KBQ49_16505	COG1192	Involved in chromosome partitioning
KBQ49_16510	COG2062	phosphohistidine phosphatase, SixA
KBQ49_16520	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KBQ49_16525	COG2050	protein possibly involved in aromatic compounds catabolism
KBQ49_16535	COG2267	carboxylic ester hydrolase activity
KBQ49_16545	COG1881	PFAM PEBP family protein
KBQ49_16550	COG1968	undecaprenyl-diphosphatase activity
KBQ49_16555	COG0174	glutamine synthetase
KBQ49_16560	COG0347	Belongs to the P(II) protein family
KBQ49_16565	COG0004	ammonium transporteR
KBQ49_16570	COG3852	Histidine kinase
KBQ49_16575	COG2204	response regulator
KBQ49_16580	COG2032	superoxide dismutase activity
KBQ49_16585	COG2032	superoxide dismutase activity
KBQ49_16595	COG0183	Belongs to the thiolase family
KBQ49_16635	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
KBQ49_16640	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
KBQ49_16650	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KBQ49_16660	COG0612	Peptidase, M16
KBQ49_16670	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KBQ49_16675	COG3177	Filamentation induced by cAMP protein fic
KBQ49_16690	COG0596	Alpha beta hydrolase
KBQ49_16700	COG0727	PFAM Uncharacterised protein family (UPF0153)
KBQ49_16705	COG0318	PFAM AMP-dependent synthetase and ligase
KBQ49_16720	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KBQ49_16730	COG1181	Belongs to the D-alanine--D-alanine ligase family
KBQ49_16745	COG4232	protein-disulfide reductase activity
KBQ49_16750	COG0564	pseudouridine synthase activity
KBQ49_16770	COG0339	signal peptide processing
KBQ49_16790	COG0583	DNA-binding transcription factor activity
KBQ49_16795	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
KBQ49_16800	COG2224	Isocitrate lyase
KBQ49_16835	COG0659	secondary active sulfate transmembrane transporter activity
KBQ49_16865	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KBQ49_16870	COG2130	NADP-dependent
KBQ49_16885	COG1187	pseudouridine synthase activity
KBQ49_16895	COG1643	Atp-dependent helicase
KBQ49_16900	COG0084	hydrolase, TatD family'
KBQ49_16980	COG0842	Transport permease protein
KBQ49_16985	COG1131	(ABC) transporter
KBQ49_16990	COG0543	2 iron, 2 sulfur cluster binding
KBQ49_16990	COG0633	Ferredoxin
KBQ49_17000	COG1476	TRANSCRIPTIONal
KBQ49_17010	COG4555	ABC transporter
KBQ49_17105	COG1199	ATP-dependent helicase activity
KBQ49_17165	COG0628	permease
KBQ49_17175	COG2133	pyrroloquinoline quinone binding
KBQ49_17225	COG5463	Belongs to the UPF0441 family
KBQ49_17230	COG0754	glutathionylspermidine amidase activity
KBQ49_17240	COG0714	Associated with various cellular activities
KBQ49_17275	COG1522	sequence-specific DNA binding
KBQ49_17290	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KBQ49_17305	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KBQ49_17310	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KBQ49_17320	COG2203	Gaf domain
KBQ49_17320	COG4251	negative regulation of phosphorylation
KBQ49_17320	COG5001	Diguanylate cyclase
KBQ49_17320	COG3706	GGDEF domain
KBQ49_17335	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KBQ49_17370	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
KBQ49_17375	COG1040	competence protein
KBQ49_17380	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KBQ49_17410	COG0606	chelatase, subunit chli
KBQ49_17415	COG2960	long-chain fatty acid transporting porin activity
KBQ49_17435	COG1166	arginine decarboxylase activity
KBQ49_17445	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KBQ49_17450	COG1819	glycosyl
KBQ49_17455	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
KBQ49_17455	COG2755	lipolytic protein G-D-S-L family
KBQ49_17460	COG0583	DNA-binding transcription factor activity
KBQ49_17480	COG4221	oxidoreductase activity
KBQ49_17500	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KBQ49_17520	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KBQ49_17530	COG2814	Major facilitator Superfamily
KBQ49_17540	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
KBQ49_17545	COG0739	heme binding
KBQ49_17550	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KBQ49_17580	COG1064	alcohol dehydrogenase
KBQ49_17595	COG4942	peptidase
KBQ49_17600	COG0793	Belongs to the peptidase S41A family
KBQ49_17635	COG0531	amino acid
KBQ49_17640	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
KBQ49_17640	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
KBQ49_17645	COG1486	melibiose metabolic process
KBQ49_17665	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KBQ49_17665	COG1565	acr, cog1565
KBQ49_17670	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KBQ49_17675	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
KBQ49_17705	COG0109	protoheme IX farnesyltransferase activity
KBQ49_17725	COG0358	DNA primase activity
KBQ49_17730	COG1295	ribonuclease BN
KBQ49_17750	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KBQ49_17770	COG2308	Evidence 4 Homologs of previously reported genes of
KBQ49_17785	COG2133	pyrroloquinoline quinone binding
KBQ49_17805	COG0531	amino acid
KBQ49_17815	COG4948	Mandelate Racemase Muconate Lactonizing
KBQ49_17825	COG4771	TonB-dependent receptor
KBQ49_17855	COG3409	Peptidoglycan-binding domain 1 protein
KBQ49_17855	COG3501	Rhs element vgr protein
KBQ49_17890	COG5383	Protein conserved in bacteria
KBQ49_17900	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KBQ49_17905	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KBQ49_17910	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KBQ49_17925	COG1652	LysM domain
KBQ49_17935	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KBQ49_17940	COG1518	maintenance of DNA repeat elements
KBQ49_17980	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KBQ49_17990	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
KBQ49_18000	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KBQ49_18005	COG3118	belongs to the thioredoxin family
KBQ49_18015	COG2884	Cell division ATP-binding protein ftsE
KBQ49_18020	COG2177	Part of the ABC transporter FtsEX involved in
KBQ49_18025	COG2201	protein-glutamate methylesterase activity
KBQ49_18030	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KBQ49_18035	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KBQ49_18040	COG2860	membrane
KBQ49_18045	COG1252	NADH dehydrogenase
KBQ49_18055	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KBQ49_18065	COG0534	Mate efflux family protein
KBQ49_18070	COG0616	signal peptide processing
KBQ49_18080	COG1028	Short-chain dehydrogenase reductase Sdr
KBQ49_18095	COG0009	L-threonylcarbamoyladenylate synthase
KBQ49_18100	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KBQ49_18100	COG1754	DNA topoisomerase type I activity
KBQ49_18105	COG1714	RDD family
KBQ49_18120	COG0758	DNA mediated transformation
KBQ49_18125	COG1652	LysM domain
KBQ49_18130	COG0242	peptide deformylase activity
KBQ49_18135	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KBQ49_18140	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KBQ49_18140	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KBQ49_18145	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KBQ49_18155	COG3307	-O-antigen
KBQ49_18180	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KBQ49_18195	COG1490	D-aminoacyl-tRNA deacylase activity
KBQ49_18200	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KBQ49_18230	COG1609	Transcriptional regulator
KBQ49_18240	COG0366	Alpha amylase catalytic
KBQ49_18245	COG0366	Alpha amylase catalytic
KBQ49_18295	COG3704	protein secretion by the type IV secretion system
KBQ49_18380	COG1309	transcriptional regulator
KBQ49_18420	COG0840	transmembrane signaling receptor activity
KBQ49_18440	COG3546	catalase activity
KBQ49_18445	COG3685	Protein conserved in bacteria
KBQ49_18450	COG3685	Protein conserved in bacteria
KBQ49_18455	COG1028	Short-chain dehydrogenase reductase Sdr
KBQ49_18465	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
KBQ49_18480	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KBQ49_18495	COG0028	Belongs to the TPP enzyme family
KBQ49_18500	COG4191	Histidine kinase
KBQ49_18505	COG2204	response regulator
KBQ49_18530	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
KBQ49_18545	COG3645	SOS response
KBQ49_18580	COG2223	nitrite transmembrane transporter activity
KBQ49_18585	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KBQ49_18590	COG2146	nitrite reductase [NAD(P)H] activity
KBQ49_18595	COG0243	molybdopterin cofactor binding
KBQ49_18620	COG1640	4-alpha-glucanotransferase
KBQ49_18625	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KBQ49_18670	COG0181	hydroxymethylbilane synthase activity
KBQ49_18695	COG1733	regulation of RNA biosynthetic process
KBQ49_18710	COG1505	serine-type exopeptidase activity
KBQ49_18715	COG0436	Aminotransferase
KBQ49_18725	COG2832	Protein of unknown function (DUF454)
KBQ49_18735	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KBQ49_18780	COG2226	methyltransferase
KBQ49_18790	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KBQ49_18795	COG0308	aminopeptidase N
KBQ49_18800	COG0508	dehydrogenase complex catalyzes the overall conversion of
KBQ49_18800	COG0596	Alpha beta hydrolase
KBQ49_18825	COG2010	Cytochrome c
KBQ49_18835	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
KBQ49_18845	COG3284	Transcriptional regulator
KBQ49_18850	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KBQ49_18855	COG1077	Cell shape determining protein MreB Mrl
KBQ49_18860	COG1792	Involved in formation and maintenance of cell shape
KBQ49_18870	COG0768	penicillin binding
KBQ49_18875	COG0772	Belongs to the SEDS family
KBQ49_18890	COG2951	lytic endotransglycosylase activity
KBQ49_18900	COG1686	Belongs to the peptidase S11 family
KBQ49_18970	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KBQ49_19005	COG1051	belongs to the nudix hydrolase family
KBQ49_19005	COG1056	cytidyltransferase-related domain
KBQ49_19025	COG1090	epimerase
KBQ49_19035	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
KBQ49_19040	COG0673	inositol 2-dehydrogenase activity
KBQ49_19045	COG2823	Periplasmic or secreted lipoprotein
KBQ49_19055	COG2202	Pas domain
KBQ49_19055	COG2205	protein histidine kinase activity
KBQ49_19060	COG0784	Response regulator, receiver
KBQ49_19065	COG4191	Histidine kinase
KBQ49_19075	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KBQ49_19080	COG1028	Short-chain dehydrogenase reductase Sdr
KBQ49_19095	COG4305	rare lipoprotein A
KBQ49_19115	COG3250	beta-galactosidase activity
KBQ49_19130	COG2188	Transcriptional regulator
KBQ49_19135	COG0738	Major facilitator superfamily
KBQ49_19140	COG1609	Transcriptional regulator
KBQ49_19145	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KBQ49_19150	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KBQ49_19160	COG0617	tRNA 3'-terminal CCA addition
KBQ49_19180	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KBQ49_19230	COG2205	protein histidine kinase activity
KBQ49_19245	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
KBQ49_19250	COG3791	Glutathione-dependent formaldehyde-activating
KBQ49_19260	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KBQ49_19305	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
KBQ49_19325	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
KBQ49_19355	COG1162	GTPase activity
KBQ49_19380	COG2211	Major facilitator Superfamily
KBQ49_19390	COG1028	Short-chain dehydrogenase reductase Sdr
KBQ49_19395	COG2851	Citrate transporter
KBQ49_19430	COG4191	Histidine kinase
KBQ49_19440	COG1301	dicarboxylic acid transport
KBQ49_19445	COG0280	phosphate acetyltransferase
KBQ49_19445	COG0281	malic enzyme
KBQ49_19510	COG1560	Kdo2-lipid A biosynthetic process
KBQ49_19515	COG1519	Transferase
KBQ49_19520	COG1538	Outer membrane efflux protein
KBQ49_19525	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
KBQ49_19535	COG3706	GGDEF domain
KBQ49_19540	COG0473	3-isopropylmalate dehydrogenase activity
KBQ49_19545	COG0066	3-isopropylmalate dehydratase activity
KBQ49_19565	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KBQ49_19585	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KBQ49_19615	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
KBQ49_19645	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KBQ49_19655	COG0671	phosphoesterase, PA-phosphatase related
KBQ49_19670	COG1940	carbohydrate kinase activity
KBQ49_19680	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KBQ49_19690	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
KBQ49_19705	COG1773	rubredoxin
KBQ49_19720	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KBQ49_19730	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KBQ49_19755	COG3079	Belongs to the UPF0149 family
KBQ49_19760	COG0006	proline dipeptidase activity
KBQ49_19765	COG0006	proline dipeptidase activity
KBQ49_19780	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KBQ49_19800	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KBQ49_19805	COG0667	Aldo Keto reductase
KBQ49_19815	COG4771	TonB-dependent receptor
KBQ49_19835	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
KBQ49_19840	COG4181	ATPase activity
KBQ49_19855	COG0642	Histidine kinase
KBQ49_19865	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KBQ49_19870	COG0861	Integral membrane protein TerC family
KBQ49_19875	COG1704	LemA family
KBQ49_19910	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KBQ49_19915	COG2967	ApaG domain
KBQ49_19920	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KBQ49_19925	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
KBQ49_19930	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KBQ49_19945	COG2096	Adenosyltransferase
KBQ49_19955	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KBQ49_20000	COG0697	spore germination
KBQ49_20005	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KBQ49_20035	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KBQ49_20040	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KBQ49_20050	COG0583	DNA-binding transcription factor activity
KBQ49_20055	COG3634	alkyl hydroperoxide reductase activity
KBQ49_20105	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KBQ49_20240	COG4962	Type ii secretion system protein e
KBQ49_20255	COG3451	type IV secretory pathway VirB4