locus-tag	class	description
KBV71_00030	COG1064	alcohol dehydrogenase
KBV71_00035	COG2234	aminopeptidase activity
KBV71_00045	COG4942	peptidase
KBV71_00050	COG0793	Belongs to the peptidase S41A family
KBV71_00085	COG0531	amino acid
KBV71_00090	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
KBV71_00090	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
KBV71_00095	COG1486	melibiose metabolic process
KBV71_00115	COG1565	acr, cog1565
KBV71_00115	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KBV71_00120	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KBV71_00125	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
KBV71_00155	COG0109	protoheme IX farnesyltransferase activity
KBV71_00175	COG0358	DNA primase activity
KBV71_00180	COG1295	ribonuclease BN
KBV71_00200	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KBV71_00220	COG2308	Evidence 4 Homologs of previously reported genes of
KBV71_00235	COG2133	pyrroloquinoline quinone binding
KBV71_00255	COG0531	amino acid
KBV71_00265	COG4948	Mandelate Racemase Muconate Lactonizing
KBV71_00275	COG4771	TonB-dependent receptor
KBV71_00305	COG3409	Peptidoglycan-binding domain 1 protein
KBV71_00305	COG3501	Rhs element vgr protein
KBV71_00335	COG5383	Protein conserved in bacteria
KBV71_00345	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KBV71_00350	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KBV71_00355	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KBV71_00370	COG1652	LysM domain
KBV71_00380	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KBV71_00385	COG1518	maintenance of DNA repeat elements
KBV71_00420	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KBV71_00430	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
KBV71_00440	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KBV71_00445	COG3118	belongs to the thioredoxin family
KBV71_00455	COG2884	Cell division ATP-binding protein ftsE
KBV71_00460	COG2177	Part of the ABC transporter FtsEX involved in
KBV71_00465	COG2201	protein-glutamate methylesterase activity
KBV71_00470	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KBV71_00475	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KBV71_00480	COG2860	membrane
KBV71_00485	COG1252	NADH dehydrogenase
KBV71_00495	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KBV71_00505	COG0534	Mate efflux family protein
KBV71_00510	COG0616	signal peptide processing
KBV71_00520	COG1028	Short-chain dehydrogenase reductase Sdr
KBV71_00535	COG0009	L-threonylcarbamoyladenylate synthase
KBV71_00540	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KBV71_00540	COG1754	DNA topoisomerase type I activity
KBV71_00545	COG1714	RDD family
KBV71_00560	COG0758	DNA mediated transformation
KBV71_00565	COG1652	LysM domain
KBV71_00570	COG0242	peptide deformylase activity
KBV71_00575	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KBV71_00580	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KBV71_00580	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KBV71_00585	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KBV71_00595	COG3307	-O-antigen
KBV71_00620	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KBV71_00635	COG1490	D-aminoacyl-tRNA deacylase activity
KBV71_00640	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KBV71_00670	COG1609	Transcriptional regulator
KBV71_00680	COG0366	Alpha amylase catalytic
KBV71_00685	COG0366	Alpha amylase catalytic
KBV71_00735	COG0419	ATPase involved in DNA repair
KBV71_00810	COG1309	transcriptional regulator
KBV71_00850	COG0840	transmembrane signaling receptor activity
KBV71_00860	COG3685	Protein conserved in bacteria
KBV71_00865	COG3685	Protein conserved in bacteria
KBV71_00870	COG1028	Short-chain dehydrogenase reductase Sdr
KBV71_00880	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
KBV71_00900	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KBV71_00915	COG0028	Belongs to the TPP enzyme family
KBV71_00920	COG4191	Histidine kinase
KBV71_00925	COG2204	response regulator
KBV71_00950	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
KBV71_00975	COG3645	SOS response
KBV71_01010	COG2223	nitrite transmembrane transporter activity
KBV71_01015	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KBV71_01020	COG2146	nitrite reductase [NAD(P)H] activity
KBV71_01050	COG1640	4-alpha-glucanotransferase
KBV71_01055	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KBV71_01100	COG0181	hydroxymethylbilane synthase activity
KBV71_01125	COG1733	regulation of RNA biosynthetic process
KBV71_01140	COG1505	serine-type exopeptidase activity
KBV71_01145	COG0436	Aminotransferase
KBV71_01155	COG2832	Protein of unknown function (DUF454)
KBV71_01165	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KBV71_01210	COG2226	methyltransferase
KBV71_01225	COG0308	aminopeptidase N
KBV71_01230	COG0596	Alpha beta hydrolase
KBV71_01230	COG0508	dehydrogenase complex catalyzes the overall conversion of
KBV71_01255	COG2010	Cytochrome c
KBV71_01265	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
KBV71_01275	COG3284	Transcriptional regulator
KBV71_01280	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KBV71_01285	COG1077	Cell shape determining protein MreB Mrl
KBV71_01290	COG1792	Involved in formation and maintenance of cell shape
KBV71_01300	COG0768	penicillin binding
KBV71_01305	COG0772	Belongs to the SEDS family
KBV71_01325	COG2951	lytic endotransglycosylase activity
KBV71_01335	COG1686	Belongs to the peptidase S11 family
KBV71_01410	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KBV71_01445	COG1056	cytidyltransferase-related domain
KBV71_01445	COG1051	belongs to the nudix hydrolase family
KBV71_01465	COG1090	epimerase
KBV71_01475	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
KBV71_01480	COG0673	inositol 2-dehydrogenase activity
KBV71_01485	COG2823	Periplasmic or secreted lipoprotein
KBV71_01495	COG2202	Pas domain
KBV71_01495	COG2205	protein histidine kinase activity
KBV71_01500	COG0784	Response regulator, receiver
KBV71_01505	COG4191	Histidine kinase
KBV71_01515	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KBV71_01520	COG1028	Short-chain dehydrogenase reductase Sdr
KBV71_01535	COG4305	rare lipoprotein A
KBV71_01545	COG3250	beta-galactosidase activity
KBV71_01560	COG2188	Transcriptional regulator
KBV71_01565	COG0738	Major facilitator superfamily
KBV71_01570	COG1609	Transcriptional regulator
KBV71_01575	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KBV71_01580	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KBV71_01610	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KBV71_01635	COG2207	Transcriptional regulator
KBV71_01660	COG2205	protein histidine kinase activity
KBV71_01675	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
KBV71_01680	COG3791	Glutathione-dependent formaldehyde-activating
KBV71_01725	COG0804	urea catabolic process
KBV71_01730	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
KBV71_01750	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
KBV71_01780	COG1162	GTPase activity
KBV71_01805	COG2211	Major facilitator Superfamily
KBV71_01815	COG1028	Short-chain dehydrogenase reductase Sdr
KBV71_01820	COG2851	Citrate transporter
KBV71_01835	COG0642	Histidine kinase
KBV71_01865	COG1301	dicarboxylic acid transport
KBV71_01870	COG0280	phosphate acetyltransferase
KBV71_01870	COG0281	malic enzyme
KBV71_01940	COG1560	Kdo2-lipid A biosynthetic process
KBV71_01945	COG1519	Transferase
KBV71_01950	COG1538	Outer membrane efflux protein
KBV71_01955	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
KBV71_01965	COG3706	GGDEF domain
KBV71_01970	COG0473	3-isopropylmalate dehydrogenase activity
KBV71_01975	COG0066	3-isopropylmalate dehydratase activity
KBV71_01985	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KBV71_01995	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KBV71_02015	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KBV71_02020	COG0840	transmembrane signaling receptor activity
KBV71_02045	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
KBV71_02055	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
KBV71_02075	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KBV71_02085	COG0671	phosphoesterase, PA-phosphatase related
KBV71_02100	COG1940	carbohydrate kinase activity
KBV71_02110	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KBV71_02125	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
KBV71_02140	COG1773	rubredoxin
KBV71_02155	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KBV71_02165	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KBV71_02190	COG3079	Belongs to the UPF0149 family
KBV71_02195	COG0006	proline dipeptidase activity
KBV71_02200	COG0006	proline dipeptidase activity
KBV71_02220	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KBV71_02225	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KBV71_02230	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
KBV71_02235	COG1561	YicC-like family, N-terminal region
KBV71_02240	COG0194	GDP metabolic process
KBV71_02245	COG1758	RNA polymerase activity
KBV71_02250	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KBV71_02260	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KBV71_02270	COG0254	rRNA binding
KBV71_02275	COG0372	Belongs to the citrate synthase family
KBV71_02290	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
KBV71_02350	COG1301	dicarboxylic acid transport
KBV71_02355	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KBV71_02385	COG0739	heme binding
KBV71_02390	COG1376	ErfK ybiS ycfS ynhG family protein
KBV71_02425	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
KBV71_02430	COG4149	molybdate abc transporter
KBV71_02435	COG0725	ABC transporter, periplasmic molybdate-binding protein
KBV71_02445	COG0640	Transcriptional regulator
KBV71_02465	COG3047	cAMP biosynthetic process
KBV71_02470	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KBV71_02520	COG3588	fructose-bisphosphate aldolase
KBV71_02525	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
KBV71_02560	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KBV71_02575	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KBV71_02575	COG1648	precorrin-2 dehydrogenase activity
KBV71_02590	COG0784	Response regulator, receiver
KBV71_02590	COG2198	Histidine kinase
KBV71_02590	COG2205	protein histidine kinase activity
KBV71_02595	COG1393	Belongs to the ArsC family
KBV71_02625	COG0175	sulfate reduction
KBV71_02630	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KBV71_02635	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KBV71_02645	COG0529	Catalyzes the synthesis of activated sulfate
KBV71_02645	COG2895	sulfate adenylyltransferase (ATP) activity
KBV71_02650	COG0840	transmembrane signaling receptor activity
KBV71_02670	COG1115	amino acid carrier protein
KBV71_02685	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KBV71_02710	COG1609	Transcriptional regulator
KBV71_02725	COG0179	Fumarylacetoacetate (FAA) hydrolase
KBV71_02740	COG0471	metal ion transport
KBV71_02740	COG3273	potassium ion transport
KBV71_02750	COG2022	thiamine diphosphate biosynthetic process
KBV71_02775	COG0174	glutamine synthetase
KBV71_02780	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
KBV71_02790	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
KBV71_02805	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KBV71_02830	COG3511	phospholipase C
KBV71_02840	COG0189	ligase activity
KBV71_02850	COG0745	RESPONSE REGULATOR receiver
KBV71_02930	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
KBV71_02930	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KBV71_02940	COG1262	PFAM Formylglycine-generating sulfatase enzyme
KBV71_02955	COG1174	glycine betaine transport
KBV71_02960	COG1125	glycine betaine transport
KBV71_02970	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KBV71_02975	COG0564	pseudouridine synthase activity
KBV71_03000	COG3387	PFAM Glycoside hydrolase 15-related
KBV71_03050	COG0542	response to heat
KBV71_03075	COG0019	diaminopimelate decarboxylase activity
KBV71_03080	COG4264	IucA IucC family
KBV71_03085	COG2814	Major facilitator Superfamily
KBV71_03090	COG4264	IucA IucC family
KBV71_03100	COG4772	TonB-dependent receptor
KBV71_03110	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KBV71_03110	COG4651	solute:proton antiporter activity
KBV71_03200	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KBV71_03200	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KBV71_03220	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
KBV71_03260	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KBV71_03265	COG1404	Belongs to the peptidase S8 family
KBV71_03310	COG1295	ribonuclease BN
KBV71_03315	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KBV71_03340	COG0521	Mo-molybdopterin cofactor biosynthetic process
KBV71_03345	COG5297	Belongs to the glycosyl hydrolase family 6
KBV71_03445	COG3537	Alpha-1,2-mannosidase
KBV71_03470	COG1472	Belongs to the glycosyl hydrolase 3 family
KBV71_03480	COG3525	Glycosyl hydrolase, family 20, catalytic domain
KBV71_03485	COG3858	chitin binding
KBV71_03485	COG1388	LysM domain
KBV71_03500	COG0837	glucose binding
KBV71_03510	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KBV71_03520	COG0494	nUDIX hydrolase
KBV71_03525	COG1218	3'(2'),5'-bisphosphate nucleotidase
KBV71_03530	COG3956	TIGRFAM MazG family protein
KBV71_03535	COG1742	UPF0060 membrane protein
KBV71_03540	COG0330	HflC and HflK could
KBV71_03575	COG0697	spore germination
KBV71_03605	COG2124	cytochrome p450
KBV71_03610	COG2124	cytochrome p450
KBV71_03615	COG1141	Ferredoxin
KBV71_03620	COG1028	Short-chain dehydrogenase reductase Sdr
KBV71_03625	COG2124	cytochrome p450
KBV71_03630	COG0142	geranyltranstransferase activity
KBV71_03635	COG1657	PFAM Prenyltransferase squalene oxidase
KBV71_03645	COG1304	FMN binding
KBV71_03665	COG4206	TonB-dependent receptor
KBV71_03675	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KBV71_03680	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KBV71_03685	COG0463	Glycosyl transferase, family 2
KBV71_03690	COG0517	IMP dehydrogenase activity
KBV71_03695	COG2982	Protein involved in outer membrane biogenesis
KBV71_03700	COG1272	protein, Hemolysin III
KBV71_03705	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KBV71_03715	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KBV71_03720	COG0626	cystathionine gamma-synthase activity
KBV71_03725	COG0460	homoserine dehydrogenase
KBV71_03725	COG0527	aspartate kinase activity
KBV71_03730	COG2267	carboxylic ester hydrolase activity
KBV71_03735	COG3706	GGDEF domain
KBV71_03740	COG1760	l-serine dehydratase
KBV71_03755	COG3038	cytochrome b561
KBV71_03775	COG2814	Major facilitator Superfamily
KBV71_03780	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KBV71_03795	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KBV71_03800	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KBV71_03815	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KBV71_03875	COG0519	Catalyzes the synthesis of GMP from XMP
KBV71_03890	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KBV71_03910	COG0840	transmembrane signaling receptor activity
KBV71_03920	COG1113	amino acid transport
KBV71_03940	COG2239	Acts as a magnesium transporter
KBV71_03945	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KBV71_03950	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KBV71_03960	COG1660	Displays ATPase and GTPase activities
KBV71_03970	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KBV71_03985	COG1137	ATPase activity
KBV71_04000	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
KBV71_04045	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KBV71_04065	COG0628	permease
KBV71_04075	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KBV71_04080	COG3178	'Phosphotransferase
KBV71_04095	COG1555	photosystem II stabilization
KBV71_04115	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KBV71_04120	COG1477	protein flavinylation
KBV71_04145	COG4774	siderophore transport
KBV71_04150	COG2146	nitrite reductase [NAD(P)H] activity
KBV71_04160	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KBV71_04165	COG0719	Fe-S assembly protein
KBV71_04170	COG0396	ATPase activity
KBV71_04175	COG0719	Fe-S assembly protein
KBV71_04190	COG0693	protein deglycase activity
KBV71_04205	COG0739	heme binding
KBV71_04220	COG1764	response to oxidative stress
KBV71_04230	COG0384	phenazine biosynthesis protein PhzF
KBV71_04235	COG0527	aspartate kinase activity
KBV71_04260	COG0142	geranyltranstransferase activity
KBV71_04265	COG0629	single-stranded DNA binding
KBV71_04270	COG3550	peptidyl-serine autophosphorylation
KBV71_04285	COG3104	oligopeptide transport
KBV71_04290	COG1297	OPT oligopeptide transporter protein
KBV71_04295	COG0823	Involved in the tonB-independent uptake of proteins
KBV71_04295	COG1506	peptidase
KBV71_04315	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KBV71_04320	COG2879	small protein
KBV71_04325	COG1966	Carbon starvation protein
KBV71_04390	COG3706	GGDEF domain
KBV71_04390	COG4251	negative regulation of phosphorylation
KBV71_04390	COG5001	Diguanylate cyclase
KBV71_04390	COG2203	Gaf domain
KBV71_04395	COG0835	chemotaxis
KBV71_04400	COG0840	transmembrane signaling receptor activity
KBV71_04405	COG0840	transmembrane signaling receptor activity
KBV71_04415	COG0643	Histidine kinase
KBV71_04415	COG2198	Histidine kinase
KBV71_04445	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
KBV71_04455	COG2205	protein histidine kinase activity
KBV71_04490	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KBV71_04495	COG0735	belongs to the Fur family
KBV71_04530	COG1529	Aldehyde oxidase and xanthine dehydrogenase
KBV71_04535	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
KBV71_04540	COG2080	2 iron, 2 sulfur cluster binding
KBV71_04640	COG1187	pseudouridine synthase activity
KBV71_04665	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KBV71_04685	COG1132	(ABC) transporter
KBV71_04705	COG0583	DNA-binding transcription factor activity
KBV71_04770	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KBV71_04775	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KBV71_04785	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KBV71_04790	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KBV71_04795	COG0750	zinc metalloprotease
KBV71_04800	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
KBV71_04805	COG0575	Belongs to the CDS family
KBV71_04810	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KBV71_04820	COG0528	UMP kinase activity
KBV71_04830	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KBV71_04870	COG0024	Methionine aminopeptidase
KBV71_04890	COG1393	Belongs to the ArsC family
KBV71_04895	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KBV71_04910	COG0367	asparagine synthase
KBV71_04945	COG1566	PFAM secretion protein HlyD family protein
KBV71_04950	COG2814	Major facilitator Superfamily
KBV71_04985	COG0557	exoribonuclease II activity
KBV71_04995	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KBV71_05005	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KBV71_05025	COG0704	Plays a role in the regulation of phosphate uptake
KBV71_05035	COG0581	inorganic phosphate transmembrane transporter activity
KBV71_05045	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KBV71_05050	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KBV71_05070	COG0659	secondary active sulfate transmembrane transporter activity
KBV71_05075	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KBV71_05085	COG1024	Enoyl-CoA hydratase
KBV71_05145	COG0784	Response regulator, receiver
KBV71_05145	COG2205	protein histidine kinase activity
KBV71_05145	COG5002	protein histidine kinase activity
KBV71_05150	COG2733	membrane
KBV71_05170	COG0686	Belongs to the AlaDH PNT family
KBV71_05175	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KBV71_05180	COG1917	Cupin 2, conserved barrel domain protein
KBV71_05180	COG1396	sequence-specific DNA binding
KBV71_05185	COG1012	belongs to the aldehyde dehydrogenase family
KBV71_05205	COG2223	nitrite transmembrane transporter activity
KBV71_05215	COG0243	molybdopterin cofactor binding
KBV71_05250	COG0477	Major facilitator Superfamily
KBV71_05260	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KBV71_05265	COG0174	glutamine synthetase
KBV71_05270	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
KBV71_05275	COG0174	glutamine synthetase
KBV71_05285	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
KBV71_05290	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
KBV71_05310	COG3842	ATPase activity
KBV71_05315	COG1176	ABC-type spermidine putrescine transport system, permease component I
KBV71_05320	COG1177	transmembrane transport
KBV71_05325	COG1012	belongs to the aldehyde dehydrogenase family
KBV71_05340	COG4535	Mg2 and Co2 transporter CorC
KBV71_05355	COG1702	phosphate starvation-inducible protein PhoH
KBV71_05375	COG0723	plastoquinol--plastocyanin reductase activity
KBV71_05380	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KBV71_05390	COG2857	Cytochrome c1
KBV71_05395	COG0625	glutathione transferase activity
KBV71_05400	COG2969	positive regulation of protein catabolic process
KBV71_05440	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
KBV71_05445	COG1028	Short-chain dehydrogenase reductase Sdr
KBV71_05450	COG2095	MarC family integral membrane protein
KBV71_05460	COG1611	Belongs to the LOG family
KBV71_05465	COG3275	phosphorelay sensor kinase activity
KBV71_05510	COG0556	nucleotide-excision repair
KBV71_05545	COG2948	multi-organism process
KBV71_05645	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KBV71_05655	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KBV71_05660	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KBV71_05710	COG0438	transferase activity, transferring glycosyl groups
KBV71_05715	COG0438	transferase activity, transferring glycosyl groups
KBV71_05725	COG0438	transferase activity, transferring glycosyl groups
KBV71_05745	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KBV71_05755	COG1960	acyl-CoA dehydrogenase activity
KBV71_05790	COG1570	exodeoxyribonuclease VII activity
KBV71_05795	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KBV71_05800	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KBV71_05800	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
KBV71_05805	COG0802	atpase or kinase
KBV71_05810	COG0860	N-Acetylmuramoyl-L-alanine amidase
KBV71_05815	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KBV71_05835	COG1028	Short-chain dehydrogenase reductase Sdr
KBV71_05860	COG4681	YaeQ
KBV71_05865	COG0564	pseudouridine synthase activity
KBV71_05875	COG0625	glutathione transferase activity
KBV71_05880	COG0657	acetylesterase activity
KBV71_05885	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
KBV71_05915	COG0488	(ABC) transporter
KBV71_05930	COG4290	ribonuclease
KBV71_05935	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KBV71_05945	COG1472	Belongs to the glycosyl hydrolase 3 family
KBV71_05985	COG1846	Transcriptional regulator
KBV71_06000	COG0386	Belongs to the glutathione peroxidase family
KBV71_06075	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KBV71_06080	COG0084	hydrolase, TatD family'
KBV71_06095	COG1960	acyl-CoA dehydrogenase activity
KBV71_06105	COG0305	Participates in initiation and elongation during chromosome replication
KBV71_06110	COG0415	Belongs to the DNA photolyase family
KBV71_06125	COG0583	DNA-binding transcription factor activity
KBV71_06140	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KBV71_06180	COG1404	Belongs to the peptidase S8 family
KBV71_06185	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
KBV71_06190	COG2867	negative regulation of translational initiation
KBV71_06200	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KBV71_06205	COG0735	belongs to the Fur family
KBV71_06210	COG0497	DNA recombination
KBV71_06215	COG1420	regulation of RNA biosynthetic process
KBV71_06220	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KBV71_06225	COG0443	Heat shock 70 kDa protein
KBV71_06230	COG0484	heat shock protein binding
KBV71_06235	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
KBV71_06240	COG0287	Prephenate dehydrogenase
KBV71_06240	COG1605	Chorismate mutase
KBV71_06250	COG1132	(ABC) transporter
KBV71_06310	COG2850	peptidyl-arginine hydroxylation
KBV71_06365	COG1131	(ABC) transporter
KBV71_06370	COG1725	Transcriptional regulator
KBV71_06395	COG2900	Belongs to the SlyX family
KBV71_06405	COG2755	lipolytic protein G-D-S-L family
KBV71_06405	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
KBV71_06415	COG0646	methionine synthase
KBV71_06415	COG1410	methionine synthase
KBV71_06420	COG0646	methionine synthase
KBV71_06420	COG1410	methionine synthase
KBV71_06425	COG2226	methyltransferase
KBV71_06430	COG1960	acyl-CoA dehydrogenase activity
KBV71_06460	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KBV71_06465	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KBV71_06475	COG2902	Dehydrogenase
KBV71_06525	COG2925	Exonuclease
KBV71_06535	COG3844	kynureninase activity
KBV71_06550	COG0288	reversible hydration of carbon dioxide
KBV71_06620	COG0316	Belongs to the HesB IscA family
KBV71_06655	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KBV71_06665	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
KBV71_06710	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
KBV71_06725	COG1228	amidohydrolase
KBV71_06740	COG4221	oxidoreductase activity
KBV71_06780	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KBV71_06785	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KBV71_06790	COG0077	Prephenate dehydratase
KBV71_06790	COG1605	Chorismate mutase
KBV71_06815	COG0583	DNA-binding transcription factor activity
KBV71_06860	COG1136	(ABC) transporter
KBV71_06860	COG0577	efflux transmembrane transporter activity
KBV71_06890	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KBV71_06890	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KBV71_06895	COG1105	Belongs to the carbohydrate kinase PfkB family
KBV71_06900	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KBV71_06900	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
KBV71_06905	COG1609	Transcriptional regulator
KBV71_06915	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
KBV71_06955	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KBV71_06970	COG1253	flavin adenine dinucleotide binding
KBV71_06980	COG0306	phosphate transporter
KBV71_07005	COG0504	CTP synthase activity
KBV71_07020	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
KBV71_07025	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
KBV71_07030	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
KBV71_07045	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
KBV71_07055	COG1238	metal cluster binding
KBV71_07070	COG1534	Rna-binding protein
KBV71_07075	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
KBV71_07080	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KBV71_07090	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KBV71_07095	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KBV71_07105	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KBV71_07110	COG1546	Belongs to the CinA family
KBV71_07115	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
KBV71_07120	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KBV71_07125	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KBV71_07130	COG2137	regulation of response to DNA damage stimulus
KBV71_07190	COG1294	oxidase, subunit
KBV71_07200	COG4988	ABC transporter
KBV71_07205	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KBV71_07215	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KBV71_07260	COG4133	protoheme IX ABC transporter activity
KBV71_07265	COG0436	Aminotransferase
KBV71_07290	COG1187	pseudouridine synthase activity
KBV71_07300	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KBV71_07305	COG2350	Protein conserved in bacteria
KBV71_07340	COG0395	ABC-type sugar transport system, permease component
KBV71_07355	COG0129	dihydroxy-acid dehydratase activity
KBV71_07370	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KBV71_07390	COG2009	succinate dehydrogenase
KBV71_07395	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
KBV71_07410	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
KBV71_07420	COG4591	ABC-type transport system involved in lipoprotein release permease component
KBV71_07440	COG0811	peptide transport
KBV71_07450	COG1132	(ABC) transporter
KBV71_07455	COG1663	tetraacyldisaccharide 4'-kinase activity
KBV71_07465	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KBV71_07480	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KBV71_07490	COG0582	viral genome integration into host DNA
KBV71_07755	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
KBV71_07760	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KBV71_07770	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KBV71_07805	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KBV71_07810	COG2258	MOSC domain
KBV71_07820	COG0505	Belongs to the CarA family
KBV71_07835	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KBV71_07845	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KBV71_07925	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
KBV71_07945	COG1024	Enoyl-CoA hydratase
KBV71_07955	COG1024	Enoyl-CoA hydratase
KBV71_07960	COG1024	Enoyl-CoA hydratase
KBV71_07980	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KBV71_07990	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KBV71_08005	COG0346	lactoylglutathione lyase activity
KBV71_08015	COG1304	FMN binding
KBV71_08020	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KBV71_08025	COG1649	PFAM Uncharacterised BCR, COG1649
KBV71_08100	COG0784	Response regulator, receiver
KBV71_08100	COG2205	protein histidine kinase activity
KBV71_08105	COG2183	response to ionizing radiation
KBV71_08110	COG0784	Response regulator, receiver
KBV71_08110	COG4191	Histidine kinase
KBV71_08120	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KBV71_08120	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
KBV71_08140	COG3243	poly(R)-hydroxyalkanoic acid synthase
KBV71_08150	COG1183	phosphatidylcholine synthase activity
KBV71_08170	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
KBV71_08180	COG0668	transmembrane transport
KBV71_08185	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
KBV71_08210	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
KBV71_08215	COG1501	Belongs to the glycosyl hydrolase 31 family
KBV71_08280	COG0519	Catalyzes the synthesis of GMP from XMP
KBV71_08280	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KBV71_08290	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KBV71_08305	COG0475	glutathione-regulated potassium exporter activity
KBV71_08305	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KBV71_08310	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KBV71_08320	COG0746	molybdenum cofactor guanylyltransferase activity
KBV71_08330	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KBV71_08340	COG1426	Protein conserved in bacteria
KBV71_08350	COG0820	rRNA (adenine-C2-)-methyltransferase activity
KBV71_08365	COG1024	Enoyl-CoA hydratase
KBV71_08365	COG1250	3-hydroxyacyl-CoA dehydrogenase
KBV71_08370	COG0183	Belongs to the thiolase family
KBV71_08375	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KBV71_08385	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KBV71_08390	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
KBV71_08400	COG0776	regulation of translation
KBV71_08405	COG0539	negative regulation of cytoplasmic translation
KBV71_08410	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
KBV71_08415	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KBV71_08425	COG2957	Belongs to the agmatine deiminase family
KBV71_08430	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KBV71_08450	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KBV71_08470	COG0316	Belongs to the HesB IscA family
KBV71_08470	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
KBV71_08485	COG0428	transporter
KBV71_08525	COG2801	Transposase and inactivated derivatives
KBV71_08545	COG0512	Glutamine amidotransferase of anthranilate synthase
KBV71_08575	COG1022	Amp-dependent synthetase and ligase
KBV71_08610	COG1132	(ABC) transporter
KBV71_08630	COG0438	transferase activity, transferring glycosyl groups
KBV71_08635	COG0438	transferase activity, transferring glycosyl groups
KBV71_08655	COG4106	trans-aconitate 2-methyltransferase activity
KBV71_08675	COG2244	polysaccharide biosynthetic process
KBV71_08705	COG3038	cytochrome b561
KBV71_08725	COG1595	DNA-templated transcription, initiation
KBV71_08780	COG0038	chloride channel
KBV71_08785	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KBV71_08805	COG1674	ftsk spoiiie
KBV71_08810	COG0492	ferredoxin-NADP+ reductase activity
KBV71_08820	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
KBV71_08850	COG0482	sulfurtransferase activity
KBV71_08855	COG2915	High frequency lysogenization protein hflD homolog
KBV71_08915	COG0784	Response regulator, receiver
KBV71_08915	COG0835	chemotaxis
KBV71_08925	COG1558	bacterial-type flagellum-dependent cell motility
KBV71_08935	COG1749	Flagellar hook protein flgE
KBV71_08950	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
KBV71_08965	COG1256	bacterial-type flagellum assembly
KBV71_08965	COG1256	bacterial-type flagellum assembly
KBV71_08965	COG4786	Flagellar basal body rod
KBV71_08965	COG4786	Flagellar basal body rod
KBV71_08970	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KBV71_08975	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KBV71_08980	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
KBV71_09000	COG2197	response regulator
KBV71_09005	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
KBV71_09010	COG2201	protein-glutamate methylesterase activity
KBV71_09030	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KBV71_09035	COG1028	Short-chain dehydrogenase reductase Sdr
KBV71_09040	COG1028	Short-chain dehydrogenase reductase Sdr
KBV71_09095	COG1677	Flagellar hook-basal body complex protein FliE
KBV71_09145	COG3190	flagellar
KBV71_09155	COG1987	bacterial-type flagellum assembly
KBV71_09160	COG1684	flagellar biosynthetic protein fliR
KBV71_09205	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
KBV71_09210	COG0643	Histidine kinase
KBV71_09210	COG0784	Response regulator, receiver
KBV71_09210	COG2198	Histidine kinase
KBV71_09215	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KBV71_09225	COG1192	Involved in chromosome partitioning
KBV71_09230	COG0835	chemotaxis
KBV71_09240	COG0745	RESPONSE REGULATOR receiver
KBV71_09255	COG0840	transmembrane signaling receptor activity
KBV71_09260	COG0840	transmembrane signaling receptor activity
KBV71_09265	COG0840	transmembrane signaling receptor activity
KBV71_09270	COG0840	transmembrane signaling receptor activity
KBV71_09270	COG0840	transmembrane signaling receptor activity
KBV71_09280	COG0840	transmembrane signaling receptor activity
KBV71_09290	COG0840	transmembrane signaling receptor activity
KBV71_09295	COG0840	transmembrane signaling receptor activity
KBV71_09300	COG0840	transmembrane signaling receptor activity
KBV71_09310	COG0840	transmembrane signaling receptor activity
KBV71_09320	COG0835	chemotaxis
KBV71_09330	COG0840	transmembrane signaling receptor activity
KBV71_09340	COG0840	transmembrane signaling receptor activity
KBV71_09365	COG3706	GGDEF domain
KBV71_09395	COG0318	PFAM AMP-dependent synthetase and ligase
KBV71_09400	COG1024	Enoyl-CoA hydratase
KBV71_09440	COG0800	Aldolase
KBV71_09455	COG3734	2-keto-3-deoxy-galactonokinase
KBV71_09460	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
KBV71_09470	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KBV71_09480	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KBV71_09485	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
KBV71_09500	COG0351	phosphomethylpyrimidine kinase
KBV71_09520	COG0583	DNA-binding transcription factor activity
KBV71_09525	COG1741	Belongs to the pirin family
KBV71_09570	COG1024	Enoyl-CoA hydratase
KBV71_09585	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KBV71_09605	COG0277	FAD linked oxidase domain protein
KBV71_09610	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KBV71_09625	COG0531	amino acid
KBV71_09630	COG0531	amino acid
KBV71_09640	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
KBV71_09660	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KBV71_09660	COG0140	phosphoribosyl-ATP diphosphatase activity
KBV71_09675	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KBV71_09685	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KBV71_09690	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KBV71_09695	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
KBV71_09705	COG0124	histidyl-tRNA synthetase
KBV71_09710	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KBV71_09720	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KBV71_09730	COG2951	lytic endotransglycosylase activity
KBV71_09740	COG0460	homoserine dehydrogenase
KBV71_09740	COG0527	aspartate kinase activity
KBV71_09755	COG1012	belongs to the aldehyde dehydrogenase family
KBV71_09770	COG0167	dihydroorotate dehydrogenase activity
KBV71_09775	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KBV71_09800	COG0671	phosphoesterase, PA-phosphatase related
KBV71_09815	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
KBV71_09835	COG0166	Belongs to the GPI family
KBV71_09850	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
KBV71_09860	COG0617	tRNA 3'-terminal CCA addition
KBV71_09880	COG0860	N-Acetylmuramoyl-L-alanine amidase
KBV71_09885	COG0477	Major facilitator Superfamily
KBV71_09890	COG2115	Belongs to the xylose isomerase family
KBV71_09895	COG1070	Carbohydrate kinase
KBV71_09905	COG1501	Belongs to the glycosyl hydrolase 31 family
KBV71_09925	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KBV71_09945	COG0165	Argininosuccinate lyase
KBV71_09950	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KBV71_09960	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
KBV71_09965	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KBV71_09970	COG0137	argininosuccinate synthase activity
KBV71_09975	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KBV71_09990	COG2166	iron-sulfur cluster assembly
KBV71_10060	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
KBV71_10075	COG4677	pectinesterase activity
KBV71_10105	COG0402	S-adenosylhomocysteine deaminase activity
KBV71_10110	COG3548	integral membrane protein
KBV71_10120	COG1509	lysine 2,3-aminomutase activity
KBV71_10125	COG2203	Gaf domain
KBV71_10125	COG3706	GGDEF domain
KBV71_10125	COG4251	negative regulation of phosphorylation
KBV71_10125	COG5001	Diguanylate cyclase
KBV71_10150	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KBV71_10155	COG1862	Preprotein translocase
KBV71_10165	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KBV71_10175	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KBV71_10185	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KBV71_10190	COG3291	Pkd domain containing protein
KBV71_10195	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KBV71_10200	COG0405	Gamma-glutamyltransferase
KBV71_10205	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
KBV71_10220	COG0742	ribosomal rna small subunit methyltransferase
KBV71_10245	COG4771	TonB-dependent receptor
KBV71_10255	COG3507	Belongs to the glycosyl hydrolase 43 family
KBV71_10265	COG4206	TonB-dependent receptor
KBV71_10290	COG0531	amino acid
KBV71_10305	COG0006	proline dipeptidase activity
KBV71_10315	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KBV71_10330	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KBV71_10335	COG3938	Belongs to the proline racemase family
KBV71_10345	COG0552	protein localization to endoplasmic reticulum
KBV71_10350	COG1194	a g-specific adenine glycosylase
KBV71_10400	COG0840	transmembrane signaling receptor activity
KBV71_10405	COG0840	transmembrane signaling receptor activity
KBV71_10425	COG3300	MHYT domain
KBV71_10425	COG5001	Diguanylate cyclase
KBV71_10435	COG1185	polyribonucleotide nucleotidyltransferase activity
KBV71_10445	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KBV71_10460	COG0195	Participates in both transcription termination and antitermination
KBV71_10475	COG1007	ATP synthesis coupled electron transport
KBV71_10515	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
KBV71_10520	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
KBV71_10525	COG0649	NAD binding
KBV71_10530	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KBV71_10540	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KBV71_10570	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KBV71_10630	COG2890	protein-(glutamine-N5) methyltransferase activity
KBV71_10640	COG0688	phosphatidylethanolamine metabolic process
KBV71_10645	COG0741	lytic transglycosylase activity
KBV71_10650	COG0433	COG0433 Predicted ATPase
KBV71_10655	COG0494	nUDIX hydrolase
KBV71_10670	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KBV71_10690	COG1714	RDD family
KBV71_10695	COG0717	Belongs to the dCTP deaminase family
KBV71_10700	COG0489	protein tyrosine kinase activity
KBV71_10710	COG4771	TonB-dependent receptor
KBV71_10720	COG4771	TonB-dependent receptor
KBV71_10725	COG0457	Tetratricopeptide repeat
KBV71_10740	COG3590	peptidase
KBV71_10780	COG0697	spore germination
KBV71_10800	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KBV71_10805	COG2311	Membrane
KBV71_10810	COG1047	Peptidyl-prolyl cis-trans
KBV71_10815	COG0791	NLP P60 protein
KBV71_10820	COG0791	NLP P60 protein
KBV71_10835	COG1607	acyl-coa hydrolase
KBV71_10845	COG1301	dicarboxylic acid transport
KBV71_10850	COG1785	Belongs to the alkaline phosphatase family
KBV71_10860	COG0037	tRNA processing
KBV71_10865	COG1722	exodeoxyribonuclease VII activity
KBV71_10870	COG0142	geranyltranstransferase activity
KBV71_10880	COG1858	cytochrome C peroxidase
KBV71_10905	COG0515	serine threonine protein kinase
KBV71_10905	COG2815	serine threonine protein kinase
KBV71_10910	COG0631	protein serine/threonine phosphatase activity
KBV71_11010	COG0312	modulator of DNA gyrase
KBV71_11020	COG0312	modulator of DNA gyrase
KBV71_11040	COG2968	Membrane
KBV71_11055	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KBV71_11070	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KBV71_11085	COG0495	leucyl-tRNA aminoacylation
KBV71_11095	COG3118	belongs to the thioredoxin family
KBV71_11110	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
KBV71_11120	COG2040	homocysteine
KBV71_11125	COG0833	amino acid
KBV71_11135	COG0346	lactoylglutathione lyase activity
KBV71_11155	COG2878	Part of a membrane complex involved in electron transport
KBV71_11170	COG1595	DNA-templated transcription, initiation
KBV71_11195	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KBV71_11215	COG0251	oxidation-reduction process
KBV71_11225	COG0392	lysyltransferase activity
KBV71_11225	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KBV71_11255	COG2814	Major facilitator Superfamily
KBV71_11260	COG1902	pentaerythritol trinitrate reductase activity
KBV71_11265	COG2824	Alkylphosphonate utilization operon protein PhnA
KBV71_11270	COG1047	Peptidyl-prolyl cis-trans
KBV71_11275	COG1077	Cell shape determining protein MreB Mrl
KBV71_11310	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KBV71_11320	COG1451	nucleotide metabolic process
KBV71_11340	COG0784	Response regulator, receiver
KBV71_11340	COG2198	Histidine kinase
KBV71_11340	COG2205	protein histidine kinase activity
KBV71_11350	COG2186	Transcriptional regulator
KBV71_11355	COG3250	beta-galactosidase activity
KBV71_11420	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
KBV71_11420	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
KBV71_11420	COG1703	isobutyryl-CoA mutase activity
KBV71_11450	COG0183	Belongs to the thiolase family
KBV71_11460	COG0443	Heat shock 70 kDa protein
KBV71_11490	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
KBV71_11490	COG1793	dna ligase
KBV71_11495	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
KBV71_11495	COG1793	dna ligase
KBV71_11500	COG1201	RNA secondary structure unwinding
KBV71_11510	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KBV71_11515	COG1278	Cold shock
KBV71_11520	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
KBV71_11525	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
KBV71_11530	COG1472	Belongs to the glycosyl hydrolase 3 family
KBV71_11540	COG2954	triphosphatase activity
KBV71_11555	COG1381	Involved in DNA repair and RecF pathway recombination
KBV71_11575	COG0681	Belongs to the peptidase S26 family
KBV71_11580	COG0481	GTPase activity
KBV71_11585	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KBV71_11600	COG1250	3-hydroxyacyl-CoA dehydrogenase
KBV71_11600	COG1024	Enoyl-CoA hydratase
KBV71_11620	COG2855	membrane
KBV71_11635	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KBV71_11655	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
KBV71_11665	COG0534	Mate efflux family protein
KBV71_11670	COG0335	large ribosomal subunit rRNA binding
KBV71_11675	COG0336	Belongs to the RNA methyltransferase TrmD family
KBV71_11680	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KBV71_11695	COG2070	2-Nitropropane dioxygenase
KBV71_11700	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KBV71_11715	COG3534	alpha-L-arabinofuranosidase
KBV71_11725	COG0475	glutathione-regulated potassium exporter activity
KBV71_11735	COG0625	glutathione transferase activity
KBV71_11740	COG1082	Xylose isomerase domain protein TIM barrel
KBV71_11750	COG1172	Belongs to the binding-protein-dependent transport system permease family
KBV71_11755	COG1172	Belongs to the binding-protein-dependent transport system permease family
KBV71_11760	COG1129	ABC transporter
KBV71_11765	COG1879	ABC-type sugar transport system periplasmic component
KBV71_11770	COG1012	belongs to the aldehyde dehydrogenase family
KBV71_11790	COG0129	dihydroxy-acid dehydratase activity
KBV71_11820	COG2207	Transcriptional regulator
KBV71_11865	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KBV71_11890	COG4794	Type iii secretion
KBV71_11920	COG0745	RESPONSE REGULATOR receiver
KBV71_11945	COG1595	DNA-templated transcription, initiation
KBV71_11975	COG0156	8-amino-7-oxononanoate synthase activity
KBV71_11985	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
KBV71_11990	COG1845	cytochrome c oxidase, subunit III
KBV71_11995	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KBV71_12025	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
KBV71_12040	COG0196	riboflavin kinase activity
KBV71_12055	COG0728	peptidoglycan biosynthetic process
KBV71_12065	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KBV71_12070	COG0211	Belongs to the bacterial ribosomal protein bL27 family
KBV71_12075	COG0261	This protein binds to 23S rRNA in the presence of protein L20
KBV71_12080	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KBV71_12085	COG0824	Thioesterase
KBV71_12095	COG1024	Enoyl-CoA hydratase
KBV71_12100	COG1946	Acyl-CoA thioesterase
KBV71_12115	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
KBV71_12155	COG1073	alpha beta
KBV71_12180	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KBV71_12225	COG1643	Atp-dependent helicase
KBV71_12230	COG0783	Belongs to the Dps family
KBV71_12235	COG0514	ATP-dependent DNA helicase (RecQ)
KBV71_12255	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KBV71_12260	COG0602	queuosine metabolic process
KBV71_12270	COG2885	chlorophyll binding
KBV71_12285	COG0848	biopolymer transport protein
KBV71_12295	COG0824	Thioesterase
KBV71_12300	COG2255	four-way junction helicase activity
KBV71_12305	COG3158	transport of potassium into the cell
KBV71_12310	COG0632	four-way junction helicase activity
KBV71_12320	COG0217	transcriptional regulatory protein
KBV71_12360	COG3142	Participates in the control of copper homeostasis
KBV71_12365	COG1446	asparaginase
KBV71_12410	COG2201	protein-glutamate methylesterase activity
KBV71_12415	COG0784	Response regulator, receiver
KBV71_12415	COG0643	Histidine kinase
KBV71_12415	COG2198	Histidine kinase
KBV71_12420	COG0840	transmembrane signaling receptor activity
KBV71_12425	COG0835	chemotaxis
KBV71_12440	COG0189	ligase activity
KBV71_12460	COG1199	ATP-dependent helicase activity
KBV71_12470	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KBV71_12475	COG1216	Glycosyl transferase, family 2
KBV71_12480	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KBV71_12500	COG4585	Histidine kinase
KBV71_12510	COG0850	regulation of cytokinetic process
KBV71_12515	COG2894	cell division
KBV71_12520	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
KBV71_12530	COG2205	protein histidine kinase activity
KBV71_12535	COG0745	RESPONSE REGULATOR receiver
KBV71_12545	COG2194	sulfuric ester hydrolase activity
KBV71_12600	COG2814	Major facilitator Superfamily
KBV71_12625	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KBV71_12625	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KBV71_12640	COG0753	catalase activity
KBV71_12665	COG1063	alcohol dehydrogenase
KBV71_12770	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
KBV71_12800	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KBV71_12810	COG0330	HflC and HflK could
KBV71_12815	COG0330	HflC and HflK could
KBV71_12820	COG0604	alcohol dehydrogenase
KBV71_12845	COG0678	peroxiredoxin activity
KBV71_12855	COG4953	penicillin-binding protein 1C
KBV71_12875	COG2373	Large extracellular alpha-helical protein
KBV71_12930	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KBV71_12945	COG0372	Belongs to the citrate synthase family
KBV71_12970	COG2161	toxin-antitoxin pair type II binding
KBV71_12975	COG4115	mRNA cleavage
KBV71_12995	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KBV71_13000	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KBV71_13005	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KBV71_13015	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KBV71_13020	COG1028	Short-chain dehydrogenase reductase Sdr
KBV71_13025	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KBV71_13030	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KBV71_13040	COG1399	metal-binding, possibly nucleic acid-binding protein
KBV71_13065	COG0714	Associated with various cellular activities
KBV71_13155	COG0314	molybdopterin synthase activity
KBV71_13160	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
KBV71_13165	COG0315	cyclic pyranopterin monophosphate synthase activity
KBV71_13175	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KBV71_13190	COG0859	PFAM glycosyl transferase family 9
KBV71_13265	COG0631	protein serine/threonine phosphatase activity
KBV71_13270	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KBV71_13275	COG0328	RNA-DNA hybrid ribonuclease activity
KBV71_13285	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KBV71_13290	COG3942	CHAP domain
KBV71_13290	COG1388	LysM domain
KBV71_13330	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KBV71_13340	COG0544	peptidyl-prolyl cis-trans isomerase activity
KBV71_13385	COG0473	3-isopropylmalate dehydrogenase activity
KBV71_13415	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KBV71_13420	COG0248	Ppx GppA phosphatase
KBV71_13425	COG0438	transferase activity, transferring glycosyl groups
KBV71_13435	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KBV71_13445	COG3291	Pkd domain containing protein
KBV71_13450	COG2833	Protein of unknown function (DUF455)
KBV71_13470	COG0285	dihydrofolate synthase activity
KBV71_13495	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
KBV71_13500	COG4208	sulfate ABC transporter
KBV71_13505	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
KBV71_13510	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
KBV71_13515	COG0156	8-amino-7-oxononanoate synthase activity
KBV71_13535	COG2885	chlorophyll binding
KBV71_13555	COG0667	Aldo Keto reductase
KBV71_13570	COG1902	pentaerythritol trinitrate reductase activity
KBV71_13570	COG0446	pyridine nucleotide-disulphide oxidoreductase
KBV71_13615	COG0625	glutathione transferase activity
KBV71_13620	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KBV71_13630	COG0039	L-malate dehydrogenase activity
KBV71_13640	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KBV71_13660	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
KBV71_13670	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
KBV71_13675	COG0203	ribosomal protein L17
KBV71_13700	COG0201	protein transport
KBV71_13710	COG1841	ribosomal large subunit assembly
KBV71_13735	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KBV71_13740	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KBV71_13745	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KBV71_13755	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KBV71_13760	COG0255	Belongs to the universal ribosomal protein uL29 family
KBV71_13785	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KBV71_13790	COG0089	rRNA binding
KBV71_13795	COG0088	Forms part of the polypeptide exit tunnel
KBV71_13805	COG0051	transcription antitermination factor activity, RNA binding
KBV71_13810	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KBV71_13815	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KBV71_13830	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KBV71_13840	COG0222	ribosome binding
KBV71_13855	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KBV71_13860	COG0250	Participates in transcription elongation, termination and antitermination
KBV71_13865	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KBV71_13875	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KBV71_13895	COG0012	GTP binding
KBV71_13900	COG0193	aminoacyl-tRNA hydrolase activity
KBV71_13910	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KBV71_13920	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KBV71_13935	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
KBV71_13940	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KBV71_13985	COG0488	(ABC) transporter
KBV71_14050	COG3634	alkyl hydroperoxide reductase activity
KBV71_14055	COG0583	DNA-binding transcription factor activity
KBV71_14070	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KBV71_14100	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KBV71_14105	COG0697	spore germination
KBV71_14145	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KBV71_14150	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KBV71_14160	COG2096	Adenosyltransferase
KBV71_14170	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
KBV71_14175	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KBV71_14180	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
KBV71_14185	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KBV71_14190	COG2967	ApaG domain
KBV71_14195	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KBV71_14225	COG1704	LemA family
KBV71_14230	COG0861	Integral membrane protein TerC family
KBV71_14235	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KBV71_14245	COG0642	Histidine kinase
KBV71_14260	COG4181	ATPase activity
KBV71_14265	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
KBV71_14285	COG4771	TonB-dependent receptor
KBV71_14295	COG0667	Aldo Keto reductase
KBV71_14300	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KBV71_14320	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KBV71_14345	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KBV71_14410	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KBV71_14420	COG0494	nUDIX hydrolase
KBV71_14470	COG0739	heme binding
KBV71_14480	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
KBV71_14485	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KBV71_14495	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KBV71_14500	COG1181	Belongs to the D-alanine--D-alanine ligase family
KBV71_14510	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KBV71_14525	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KBV71_14540	COG3116	cell division
KBV71_14545	COG0275	rRNA processing
KBV71_14550	COG2001	Belongs to the MraZ family
KBV71_14585	COG0792	nuclease activity
KBV71_14595	COG0277	FAD linked oxidase domain protein
KBV71_14600	COG0745	RESPONSE REGULATOR receiver
KBV71_14605	COG2205	protein histidine kinase activity
KBV71_14615	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
KBV71_14620	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
KBV71_14640	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
KBV71_14645	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KBV71_14650	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
KBV71_14665	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KBV71_14665	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KBV71_14675	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KBV71_14695	COG0488	(ABC) transporter
KBV71_14700	COG0242	peptide deformylase activity
KBV71_14715	COG1960	acyl-CoA dehydrogenase activity
KBV71_14735	COG1696	Membrane protein involved in D-alanine export
KBV71_14755	COG1215	transferase activity, transferring glycosyl groups
KBV71_14765	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KBV71_14820	COG2188	Transcriptional regulator
KBV71_14830	COG1450	Type ii and iii secretion system protein
KBV71_14845	COG3166	PFAM Fimbrial assembly family protein
KBV71_14855	COG4795	General secretion pathway protein
KBV71_14860	COG2165	general secretion pathway protein
KBV71_14865	COG4970	Tfp pilus assembly protein FimT
KBV71_14870	COG2165	general secretion pathway protein
KBV71_14875	COG1459	type II secretion system
KBV71_14880	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KBV71_14885	COG1404	Belongs to the peptidase S8 family
KBV71_14910	COG0840	transmembrane signaling receptor activity
KBV71_14915	COG0047	phosphoribosylformylglycinamidine synthase activity
KBV71_14915	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KBV71_14920	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KBV71_14925	COG4974	Belongs to the 'phage' integrase family
KBV71_14980	COG1183	phosphatidylcholine synthase activity
KBV71_14990	COG0442	prolyl-tRNA aminoacylation
KBV71_15005	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
KBV71_15010	COG1127	ABC transporter
KBV71_15015	COG3218	ABC-type transport auxiliary lipoprotein component
KBV71_15015	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
KBV71_15045	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KBV71_15050	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KBV71_15055	COG0662	Cupin 2, conserved barrel domain protein
KBV71_15055	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
KBV71_15080	COG2086	electron transfer activity
KBV71_15095	COG0546	phosphoglycolate phosphatase activity
KBV71_15095	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
KBV71_15100	COG0277	FAD linked oxidase domain protein
KBV71_15105	COG0300	oxidoreductase activity
KBV71_15110	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KBV71_15130	COG0493	'glutamate synthase
KBV71_15145	COG0438	transferase activity, transferring glycosyl groups
KBV71_15145	COG1216	Glycosyl transferase, family 2
KBV71_15150	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KBV71_15165	COG0626	cystathionine gamma-synthase activity
KBV71_15195	COG0625	glutathione transferase activity
KBV71_15205	COG0513	Belongs to the DEAD box helicase family
KBV71_15210	COG0720	synthase
KBV71_15220	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
KBV71_15225	COG1956	GAF domain-containing protein
KBV71_15235	COG4206	TonB-dependent receptor
KBV71_15240	COG0546	phosphoglycolate phosphatase activity
KBV71_15265	COG0339	signal peptide processing
KBV71_15270	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KBV71_15280	COG2217	Heavy metal translocating P-type atpase
KBV71_15295	COG2132	Multicopper oxidase
KBV71_15315	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KBV71_15325	COG1136	(ABC) transporter
KBV71_15335	COG1136	(ABC) transporter
KBV71_15335	COG0577	efflux transmembrane transporter activity
KBV71_15355	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KBV71_15375	COG0355	proton-transporting ATP synthase activity, rotational mechanism
KBV71_15390	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KBV71_15400	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KBV71_15410	COG0356	it plays a direct role in the translocation of protons across the membrane
KBV71_15425	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KBV71_15430	COG0508	dehydrogenase complex catalyzes the overall conversion of
KBV71_15465	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KBV71_15470	COG0697	spore germination
KBV71_15475	COG1666	GTP binding
KBV71_15485	COG1187	pseudouridine synthase activity
KBV71_15510	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KBV71_15510	COG2205	protein histidine kinase activity
KBV71_15535	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KBV71_15595	COG0842	Transport permease protein
KBV71_15600	COG1131	(ABC) transporter
KBV71_15605	COG0025	NhaP-type Na H and K H
KBV71_15615	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
KBV71_15620	COG1573	uracil-dna glycosylase
KBV71_15630	COG3384	dioxygenase
KBV71_15665	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KBV71_15670	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KBV71_15700	COG5001	Diguanylate cyclase
KBV71_15730	COG4106	trans-aconitate 2-methyltransferase activity
KBV71_15740	COG2076	Multidrug Resistance protein
KBV71_15775	COG3275	phosphorelay sensor kinase activity
KBV71_15780	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
KBV71_15800	COG0531	amino acid
KBV71_15810	COG5297	Belongs to the glycosyl hydrolase family 6
KBV71_15810	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
KBV71_15825	COG0741	lytic transglycosylase activity
KBV71_15845	COG2207	Transcriptional regulator
KBV71_15855	COG0598	Magnesium transport protein CorA
KBV71_15860	COG1113	amino acid transport
KBV71_15865	COG0697	spore germination
KBV71_15890	COG2267	carboxylic ester hydrolase activity
KBV71_15990	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KBV71_16000	COG0840	transmembrane signaling receptor activity
KBV71_16015	COG2353	YceI-like domain
KBV71_16045	COG0584	glycerophosphoryl diester phosphodiesterase
KBV71_16060	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
KBV71_16080	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KBV71_16085	COG0459	protein refolding
KBV71_16100	COG1324	tolerance protein
KBV71_16105	COG4232	protein-disulfide reductase activity
KBV71_16110	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KBV71_16120	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
KBV71_16125	COG0511	ligase activity, forming carbon-carbon bonds
KBV71_16130	COG0439	Biotin carboxylase
KBV71_16145	COG2264	protein methyltransferase activity
KBV71_16165	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
KBV71_16170	COG4589	Belongs to the CDS family
KBV71_16190	COG2267	carboxylic ester hydrolase activity
KBV71_16195	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KBV71_16200	COG0138	bifunctional purine biosynthesis protein purh
KBV71_16205	COG0151	Belongs to the GarS family
KBV71_16210	COG1289	transmembrane transporter activity
KBV71_16215	COG2814	Major facilitator Superfamily
KBV71_16255	COG2816	NAD+ diphosphatase activity
KBV71_16295	COG2906	2 iron, 2 sulfur cluster binding
KBV71_16300	COG1051	belongs to the nudix hydrolase family
KBV71_16325	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
KBV71_16340	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KBV71_16345	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KBV71_16350	COG0730	response to heat
KBV71_16360	COG0134	indole-3-glycerol-phosphate synthase activity
KBV71_16365	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KBV71_16385	COG1597	lipid kinase activity
KBV71_16400	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
KBV71_16415	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KBV71_16420	COG2111	Na H antiporter
KBV71_16420	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KBV71_16425	COG1006	Multisubunit Na H antiporter MnhC subunit
KBV71_16430	COG0651	ATP synthesis coupled electron transport
KBV71_16435	COG1863	multisubunit Na H antiporter MnhE subunit
KBV71_16440	COG2212	antiporter activity
KBV71_16445	COG1320	monovalent cation:proton antiporter activity
KBV71_16450	COG0530	calcium, potassium:sodium antiporter activity
KBV71_16465	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
KBV71_16485	COG3104	oligopeptide transport
KBV71_16505	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KBV71_16520	COG0508	dehydrogenase complex catalyzes the overall conversion of
KBV71_16530	COG3227	Zinc metalloprotease (Elastase)
KBV71_16535	COG0513	Belongs to the DEAD box helicase family
KBV71_16565	COG2354	Protein conserved in bacteria
KBV71_16585	COG3264	Mechanosensitive ion channel
KBV71_16585	COG1196	nuclear chromosome segregation
KBV71_16590	COG0604	alcohol dehydrogenase
KBV71_16590	COG3321	synthase
KBV71_16590	COG1028	Short-chain dehydrogenase reductase Sdr
KBV71_16610	COG1595	DNA-templated transcription, initiation
KBV71_16625	COG1802	Transcriptional regulator
KBV71_16640	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
KBV71_16670	COG1414	Transcriptional regulator
KBV71_16675	COG0738	Major facilitator superfamily
KBV71_16680	COG3254	rhamnose metabolic process
KBV71_16690	COG4948	Mandelate Racemase Muconate Lactonizing
KBV71_16695	COG0179	Fumarylacetoacetate (FAA) hydrolase
KBV71_16700	COG1028	Short-chain dehydrogenase reductase Sdr
KBV71_16730	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KBV71_16745	COG4807	Protein conserved in bacteria
KBV71_16765	COG4773	Receptor
KBV71_16780	COG0823	Involved in the tonB-independent uptake of proteins
KBV71_16780	COG1506	peptidase
KBV71_16865	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KBV71_16890	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KBV71_16895	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KBV71_16900	COG0753	catalase activity
KBV71_16925	COG1136	(ABC) transporter
KBV71_16930	COG0577	efflux transmembrane transporter activity
KBV71_16950	COG0697	spore germination
KBV71_16965	COG0180	Tryptophanyl-tRNA synthetase
KBV71_17000	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
KBV71_17005	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
KBV71_17005	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
KBV71_17015	COG3228	Belongs to the MtfA family
KBV71_17045	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KBV71_17070	COG2084	Dehydrogenase
KBV71_17075	COG1902	pentaerythritol trinitrate reductase activity
KBV71_17085	COG2814	Major facilitator Superfamily
KBV71_17090	COG0583	DNA-binding transcription factor activity
KBV71_17105	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KBV71_17110	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KBV71_17120	COG1764	response to oxidative stress
KBV71_17125	COG1846	Transcriptional regulator
KBV71_17130	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
KBV71_17140	COG0697	spore germination
KBV71_17145	COG0523	cobalamin synthesis protein
KBV71_17155	COG1742	UPF0060 membrane protein
KBV71_17165	COG3245	cytochrome
KBV71_17175	COG1960	acyl-CoA dehydrogenase activity
KBV71_17180	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KBV71_17220	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KBV71_17225	COG3387	PFAM Glycoside hydrolase 15-related
KBV71_17230	COG0745	RESPONSE REGULATOR receiver
KBV71_17245	COG1404	Belongs to the peptidase S8 family
KBV71_17255	COG3100	YcgL domain-containing protein
KBV71_17260	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KBV71_17270	COG0463	Glycosyl transferase, family 2
KBV71_17305	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KBV71_17320	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KBV71_17345	COG1294	oxidase, subunit
KBV71_17350	COG1271	oxidase subunit
KBV71_17370	COG0408	coproporphyrinogen oxidase activity
KBV71_17380	COG2323	membrane
KBV71_17400	COG0589	response to stress
KBV71_17425	COG0210	DNA helicase
KBV71_17475	COG0463	Glycosyl transferase, family 2
KBV71_17485	COG1475	DNA binding
KBV71_17490	COG1192	Involved in chromosome partitioning
KBV71_17495	COG0357	Ribosomal RNA small subunit methyltransferase G
KBV71_17505	COG2091	lysine biosynthetic process via aminoadipic acid
KBV71_17530	COG0477	Major facilitator Superfamily
KBV71_17555	COG1971	Probably functions as a manganese efflux pump
KBV71_17560	COG2205	protein histidine kinase activity
KBV71_17570	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KBV71_17575	COG3459	Glycosyltransferase 36 associated
KBV71_17580	COG2211	Major facilitator Superfamily
KBV71_17585	COG3265	gluconokinase activity
KBV71_17600	COG2911	Protein conserved in bacteria
KBV71_17605	COG0729	surface antigen
KBV71_17625	COG3132	Protein of unknown function, DUF480
KBV71_17675	COG0284	orotidine-5'-phosphate decarboxylase activity
KBV71_17690	COG1609	Transcriptional regulator
KBV71_17700	COG2937	Belongs to the GPAT DAPAT family
KBV71_17740	COG3693	PFAM glycoside hydrolase, family 10
KBV71_17745	COG1904	glucuronate isomerase
KBV71_17760	COG3386	PFAM SMP-30 Gluconolaconase
KBV71_17775	COG3046	protein related to deoxyribodipyrimidine photolyase
KBV71_17790	COG0246	Mannitol dehydrogenase
KBV71_17795	COG1472	Belongs to the glycosyl hydrolase 3 family
KBV71_17815	COG3661	Belongs to the glycosyl hydrolase 67 family
KBV71_17825	COG2115	Belongs to the xylose isomerase family
KBV71_17830	COG0037	tRNA processing
KBV71_17850	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KBV71_17860	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KBV71_17870	COG0805	protein transport
KBV71_17880	COG0519	Catalyzes the synthesis of GMP from XMP
KBV71_17880	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KBV71_17885	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KBV71_17905	COG0210	DNA helicase
KBV71_17910	COG1435	thymidine kinase activity
KBV71_17920	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
KBV71_17935	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
KBV71_17950	COG1119	ATPase activity
KBV71_17965	COG0706	membrane insertase activity
KBV71_17970	COG0594	ribonuclease P activity
KBV71_17985	COG0592	DNA-directed DNA polymerase activity
KBV71_17990	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KBV71_17995	COG0187	DNA topoisomerase II activity
KBV71_18005	COG0501	Belongs to the peptidase M48B family
KBV71_18035	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
KBV71_18045	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KBV71_18060	COG1280	lysine exporter protein (LysE YggA)
KBV71_18075	COG4772	TonB-dependent receptor
KBV71_18085	COG3284	Transcriptional regulator
KBV71_18090	COG1012	belongs to the aldehyde dehydrogenase family
KBV71_18125	COG1304	FMN binding
KBV71_18130	COG2186	Transcriptional regulator
KBV71_18155	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KBV71_18240	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KBV71_18260	COG4771	TonB-dependent receptor
KBV71_18310	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
KBV71_18325	COG3507	Belongs to the glycosyl hydrolase 43 family
KBV71_18330	COG1609	Transcriptional regulator
KBV71_18340	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
KBV71_18345	COG1028	Short-chain dehydrogenase reductase Sdr
KBV71_18360	COG3186	Phenylalanine-4-hydroxylase
KBV71_18365	COG1522	sequence-specific DNA binding
KBV71_18405	COG1752	Esterase of the alpha-beta hydrolase superfamily
KBV71_18420	COG0671	phosphoesterase, PA-phosphatase related
KBV71_18435	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KBV71_18470	COG1929	Belongs to the glycerate kinase type-1 family
KBV71_18480	COG0531	amino acid
KBV71_18485	COG4566	intracellular signal transduction
KBV71_18490	COG4191	Histidine kinase
KBV71_18510	COG1322	Protein conserved in bacteria
KBV71_18515	COG0386	Belongs to the glutathione peroxidase family
KBV71_18520	COG2853	Lipoprotein
KBV71_18535	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
KBV71_18540	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
KBV71_18545	COG1127	ABC transporter
KBV71_18550	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
KBV71_18560	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KBV71_18580	COG0537	adenosine 5'-monophosphoramidase activity
KBV71_18610	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KBV71_18665	COG0477	Major facilitator Superfamily
KBV71_18670	COG0302	gtp cyclohydrolase
KBV71_18700	COG0730	response to heat
KBV71_18715	COG2951	lytic endotransglycosylase activity
KBV71_18775	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
KBV71_18785	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
KBV71_18790	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
KBV71_18795	COG0493	'glutamate synthase
KBV71_18800	COG0070	glutamate synthase
KBV71_18800	COG0069	glutamate synthase activity
KBV71_18800	COG0067	glutamate synthase
KBV71_18850	COG1205	dead DEAH box helicase
KBV71_18850	COG1111	helicase
KBV71_18880	COG2271	Major facilitator Superfamily
KBV71_18925	COG2062	phosphohistidine phosphatase, SixA
KBV71_18935	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KBV71_18940	COG2050	protein possibly involved in aromatic compounds catabolism
KBV71_18950	COG2267	carboxylic ester hydrolase activity
KBV71_18960	COG1881	PFAM PEBP family protein
KBV71_18965	COG1968	undecaprenyl-diphosphatase activity
KBV71_18970	COG0174	glutamine synthetase
KBV71_18975	COG0347	Belongs to the P(II) protein family
KBV71_18980	COG0004	ammonium transporteR
KBV71_18985	COG3852	Histidine kinase
KBV71_18990	COG2204	response regulator
KBV71_18995	COG2032	superoxide dismutase activity
KBV71_19000	COG2032	superoxide dismutase activity
KBV71_19010	COG0183	Belongs to the thiolase family
KBV71_19050	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
KBV71_19055	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
KBV71_19065	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KBV71_19075	COG0612	Peptidase, M16
KBV71_19085	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KBV71_19105	COG0596	Alpha beta hydrolase
KBV71_19115	COG0727	PFAM Uncharacterised protein family (UPF0153)
KBV71_19120	COG0318	PFAM AMP-dependent synthetase and ligase
KBV71_19135	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KBV71_19145	COG1181	Belongs to the D-alanine--D-alanine ligase family
KBV71_19160	COG4232	protein-disulfide reductase activity
KBV71_19165	COG0564	pseudouridine synthase activity
KBV71_19185	COG0339	signal peptide processing
KBV71_19205	COG0583	DNA-binding transcription factor activity
KBV71_19210	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
KBV71_19215	COG2224	Isocitrate lyase
KBV71_19250	COG0659	secondary active sulfate transmembrane transporter activity
KBV71_19280	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KBV71_19285	COG2130	NADP-dependent
KBV71_19300	COG1187	pseudouridine synthase activity
KBV71_19310	COG1643	Atp-dependent helicase
KBV71_19315	COG0084	hydrolase, TatD family'
KBV71_19355	COG0842	Transport permease protein
KBV71_19360	COG1131	(ABC) transporter
KBV71_19365	COG0633	Ferredoxin
KBV71_19365	COG0543	2 iron, 2 sulfur cluster binding
KBV71_19375	COG1476	TRANSCRIPTIONal
KBV71_19385	COG4555	ABC transporter
KBV71_19405	COG0625	glutathione transferase activity
KBV71_19480	COG1199	ATP-dependent helicase activity
KBV71_19570	COG0628	permease
KBV71_19580	COG2133	pyrroloquinoline quinone binding
KBV71_19620	COG0754	glutathionylspermidine amidase activity
KBV71_19630	COG0714	Associated with various cellular activities
KBV71_19665	COG1522	sequence-specific DNA binding
KBV71_19680	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KBV71_19695	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KBV71_19700	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KBV71_19710	COG2203	Gaf domain
KBV71_19710	COG3706	GGDEF domain
KBV71_19710	COG4251	negative regulation of phosphorylation
KBV71_19710	COG5001	Diguanylate cyclase
KBV71_19725	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KBV71_19745	COG1028	Short-chain dehydrogenase reductase Sdr
KBV71_19760	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
KBV71_19765	COG1040	competence protein
KBV71_19770	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KBV71_19800	COG0606	chelatase, subunit chli
KBV71_19805	COG2960	long-chain fatty acid transporting porin activity
KBV71_19825	COG1166	arginine decarboxylase activity
KBV71_19845	COG1819	glycosyl
KBV71_19850	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
KBV71_19850	COG2755	lipolytic protein G-D-S-L family
KBV71_19855	COG0583	DNA-binding transcription factor activity
KBV71_19875	COG4221	oxidoreductase activity
KBV71_19895	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KBV71_19915	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KBV71_19925	COG2814	Major facilitator Superfamily
KBV71_19935	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
KBV71_19940	COG0739	heme binding
KBV71_19945	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)