locus-tag	class	description
KCU58_00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KCU58_00020	COG0187	DNA topoisomerase II activity
KCU58_00025	COG1266	CAAX protease self-immunity
KCU58_00030	COG0501	Belongs to the peptidase M48B family
KCU58_00070	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KCU58_00085	COG1280	lysine exporter protein (LysE YggA)
KCU58_00100	COG4772	TonB-dependent receptor
KCU58_00110	COG3284	Transcriptional regulator
KCU58_00115	COG1012	belongs to the aldehyde dehydrogenase family
KCU58_00150	COG1304	FMN binding
KCU58_00185	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KCU58_00260	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KCU58_00280	COG4771	TonB-dependent receptor
KCU58_00325	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
KCU58_00340	COG3507	Belongs to the glycosyl hydrolase 43 family
KCU58_00345	COG1609	Transcriptional regulator
KCU58_00355	COG1028	Short-chain dehydrogenase reductase Sdr
KCU58_00370	COG3186	Phenylalanine-4-hydroxylase
KCU58_00375	COG1522	sequence-specific DNA binding
KCU58_00390	COG1752	Esterase of the alpha-beta hydrolase superfamily
KCU58_00410	COG0671	phosphoesterase, PA-phosphatase related
KCU58_00425	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KCU58_00460	COG1929	Belongs to the glycerate kinase type-1 family
KCU58_00470	COG0531	amino acid
KCU58_00475	COG4566	intracellular signal transduction
KCU58_00480	COG4191	Histidine kinase
KCU58_00500	COG1322	Protein conserved in bacteria
KCU58_00505	COG0386	Belongs to the glutathione peroxidase family
KCU58_00510	COG2853	Lipoprotein
KCU58_00525	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
KCU58_00530	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
KCU58_00535	COG1127	ABC transporter
KCU58_00540	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
KCU58_00545	COG1074	ATP-dependent DNA helicase activity
KCU58_00550	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KCU58_00570	COG0537	adenosine 5'-monophosphoramidase activity
KCU58_00635	COG0477	Major facilitator Superfamily
KCU58_00640	COG0302	gtp cyclohydrolase
KCU58_00665	COG0730	response to heat
KCU58_00680	COG2951	lytic endotransglycosylase activity
KCU58_00740	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
KCU58_00745	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
KCU58_00750	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
KCU58_00755	COG0493	'glutamate synthase
KCU58_00760	COG0067	glutamate synthase
KCU58_00760	COG0069	glutamate synthase activity
KCU58_00760	COG0070	glutamate synthase
KCU58_00805	COG1111	helicase
KCU58_00805	COG1205	dead DEAH box helicase
KCU58_00835	COG2271	Major facilitator Superfamily
KCU58_00890	COG1192	Involved in chromosome partitioning
KCU58_00895	COG2062	phosphohistidine phosphatase, SixA
KCU58_00905	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KCU58_00910	COG2050	protein possibly involved in aromatic compounds catabolism
KCU58_00920	COG2267	carboxylic ester hydrolase activity
KCU58_00935	COG1881	PFAM PEBP family protein
KCU58_00940	COG1968	undecaprenyl-diphosphatase activity
KCU58_00945	COG0174	glutamine synthetase
KCU58_00950	COG0347	Belongs to the P(II) protein family
KCU58_00955	COG0004	ammonium transporteR
KCU58_00960	COG3852	Histidine kinase
KCU58_00965	COG2204	response regulator
KCU58_00970	COG2032	superoxide dismutase activity
KCU58_00975	COG2032	superoxide dismutase activity
KCU58_00985	COG0183	Belongs to the thiolase family
KCU58_01025	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
KCU58_01030	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
KCU58_01040	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KCU58_01050	COG0612	Peptidase, M16
KCU58_01060	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KCU58_01070	COG0596	Alpha beta hydrolase
KCU58_01080	COG0727	PFAM Uncharacterised protein family (UPF0153)
KCU58_01085	COG0318	PFAM AMP-dependent synthetase and ligase
KCU58_01100	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KCU58_01110	COG1181	Belongs to the D-alanine--D-alanine ligase family
KCU58_01125	COG4232	protein-disulfide reductase activity
KCU58_01130	COG0564	pseudouridine synthase activity
KCU58_01150	COG0339	signal peptide processing
KCU58_01170	COG0583	DNA-binding transcription factor activity
KCU58_01175	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
KCU58_01180	COG2224	Isocitrate lyase
KCU58_01215	COG0659	secondary active sulfate transmembrane transporter activity
KCU58_01250	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KCU58_01255	COG2130	NADP-dependent
KCU58_01270	COG1187	pseudouridine synthase activity
KCU58_01295	COG0084	hydrolase, TatD family'
KCU58_01310	COG0842	Transport permease protein
KCU58_01315	COG1131	(ABC) transporter
KCU58_01320	COG0633	Ferredoxin
KCU58_01320	COG0543	2 iron, 2 sulfur cluster binding
KCU58_01330	COG1476	TRANSCRIPTIONal
KCU58_01340	COG4555	ABC transporter
KCU58_01360	COG0625	glutathione transferase activity
KCU58_01435	COG1199	ATP-dependent helicase activity
KCU58_01495	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KCU58_01520	COG0628	permease
KCU58_01530	COG2133	pyrroloquinoline quinone binding
KCU58_01580	COG0754	glutathionylspermidine amidase activity
KCU58_01590	COG0714	Associated with various cellular activities
KCU58_01635	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KCU58_01650	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KCU58_01655	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KCU58_01680	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KCU58_01700	COG1028	Short-chain dehydrogenase reductase Sdr
KCU58_01715	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
KCU58_01725	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KCU58_01755	COG0606	chelatase, subunit chli
KCU58_01760	COG2960	long-chain fatty acid transporting porin activity
KCU58_01790	COG1166	arginine decarboxylase activity
KCU58_01805	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
KCU58_01805	COG2755	lipolytic protein G-D-S-L family
KCU58_01810	COG0583	DNA-binding transcription factor activity
KCU58_01830	COG4221	oxidoreductase activity
KCU58_01850	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KCU58_01870	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KCU58_01880	COG2814	Major facilitator Superfamily
KCU58_01890	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
KCU58_01895	COG0739	heme binding
KCU58_01900	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KCU58_01930	COG1064	alcohol dehydrogenase
KCU58_01935	COG2234	aminopeptidase activity
KCU58_01945	COG4942	peptidase
KCU58_01950	COG0793	Belongs to the peptidase S41A family
KCU58_02005	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KCU58_02005	COG1565	acr, cog1565
KCU58_02010	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KCU58_02015	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
KCU58_02045	COG0109	protoheme IX farnesyltransferase activity
KCU58_02060	COG0358	DNA primase activity
KCU58_02065	COG1295	ribonuclease BN
KCU58_02085	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KCU58_02090	COG2308	Evidence 4 Homologs of previously reported genes of
KCU58_02105	COG2133	pyrroloquinoline quinone binding
KCU58_02125	COG0531	amino acid
KCU58_02135	COG4948	Mandelate Racemase Muconate Lactonizing
KCU58_02145	COG4771	TonB-dependent receptor
KCU58_02150	COG3023	N-Acetylmuramoyl-L-alanine amidase
KCU58_02200	COG5383	Protein conserved in bacteria
KCU58_02215	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KCU58_02220	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KCU58_02235	COG1652	LysM domain
KCU58_02245	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KCU58_02250	COG1518	maintenance of DNA repeat elements
KCU58_02300	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
KCU58_02310	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KCU58_02315	COG3118	belongs to the thioredoxin family
KCU58_02325	COG2884	Cell division ATP-binding protein ftsE
KCU58_02330	COG2177	Part of the ABC transporter FtsEX involved in
KCU58_02335	COG2201	protein-glutamate methylesterase activity
KCU58_02340	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KCU58_02345	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KCU58_02350	COG2860	membrane
KCU58_02355	COG1252	NADH dehydrogenase
KCU58_02365	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KCU58_02375	COG0534	Mate efflux family protein
KCU58_02380	COG0616	signal peptide processing
KCU58_02390	COG1028	Short-chain dehydrogenase reductase Sdr
KCU58_02405	COG0009	L-threonylcarbamoyladenylate synthase
KCU58_02410	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KCU58_02410	COG1754	DNA topoisomerase type I activity
KCU58_02415	COG1714	RDD family
KCU58_02430	COG0758	DNA mediated transformation
KCU58_02435	COG1652	LysM domain
KCU58_02440	COG0242	peptide deformylase activity
KCU58_02445	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KCU58_02450	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KCU58_02450	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KCU58_02455	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KCU58_02490	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KCU58_02495	COG1247	-acetyltransferase
KCU58_02505	COG1490	D-aminoacyl-tRNA deacylase activity
KCU58_02510	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KCU58_02540	COG1609	Transcriptional regulator
KCU58_02550	COG0366	Alpha amylase catalytic
KCU58_02555	COG0366	Alpha amylase catalytic
KCU58_02605	COG1309	transcriptional regulator
KCU58_02645	COG0840	transmembrane signaling receptor activity
KCU58_02660	COG3546	catalase activity
KCU58_02665	COG3685	Protein conserved in bacteria
KCU58_02670	COG3685	Protein conserved in bacteria
KCU58_02675	COG1028	Short-chain dehydrogenase reductase Sdr
KCU58_02685	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
KCU58_02700	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KCU58_02715	COG0028	Belongs to the TPP enzyme family
KCU58_02720	COG4191	Histidine kinase
KCU58_02725	COG2204	response regulator
KCU58_02755	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
KCU58_02760	COG0732	type I restriction modification DNA specificity domain
KCU58_02785	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KCU58_02785	COG1648	precorrin-2 dehydrogenase activity
KCU58_02795	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KCU58_02795	COG1116	anion transmembrane transporter activity
KCU58_02800	COG2223	nitrite transmembrane transporter activity
KCU58_02805	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KCU58_02810	COG2146	nitrite reductase [NAD(P)H] activity
KCU58_02815	COG0243	molybdopterin cofactor binding
KCU58_02840	COG1640	4-alpha-glucanotransferase
KCU58_02845	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KCU58_02865	COG0745	RESPONSE REGULATOR receiver
KCU58_02890	COG0181	hydroxymethylbilane synthase activity
KCU58_02905	COG1733	regulation of RNA biosynthetic process
KCU58_02920	COG1505	serine-type exopeptidase activity
KCU58_02925	COG0436	Aminotransferase
KCU58_02935	COG2832	Protein of unknown function (DUF454)
KCU58_02945	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KCU58_02965	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
KCU58_02990	COG2226	methyltransferase
KCU58_02995	COG0308	aminopeptidase N
KCU58_03000	COG0596	Alpha beta hydrolase
KCU58_03000	COG0508	dehydrogenase complex catalyzes the overall conversion of
KCU58_03020	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KCU58_03025	COG1077	Cell shape determining protein MreB Mrl
KCU58_03030	COG1792	Involved in formation and maintenance of cell shape
KCU58_03040	COG0768	penicillin binding
KCU58_03045	COG0772	Belongs to the SEDS family
KCU58_03060	COG2951	lytic endotransglycosylase activity
KCU58_03070	COG1686	Belongs to the peptidase S11 family
KCU58_03105	COG0321	lipoyl(octanoyl) transferase activity
KCU58_03110	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KCU58_03135	COG1051	belongs to the nudix hydrolase family
KCU58_03135	COG1056	cytidyltransferase-related domain
KCU58_03170	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KCU58_03175	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KCU58_03180	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
KCU58_03185	COG1561	YicC-like family, N-terminal region
KCU58_03190	COG0194	GDP metabolic process
KCU58_03195	COG1758	RNA polymerase activity
KCU58_03200	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KCU58_03220	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KCU58_03230	COG0254	rRNA binding
KCU58_03235	COG0372	Belongs to the citrate synthase family
KCU58_03250	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KCU58_03270	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KCU58_03275	COG0667	Aldo Keto reductase
KCU58_03285	COG4771	TonB-dependent receptor
KCU58_03305	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
KCU58_03310	COG4181	ATPase activity
KCU58_03325	COG0642	Histidine kinase
KCU58_03335	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KCU58_03340	COG0861	Integral membrane protein TerC family
KCU58_03345	COG1704	LemA family
KCU58_03390	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KCU58_03400	COG1215	transferase activity, transferring glycosyl groups
KCU58_03425	COG0242	peptide deformylase activity
KCU58_03435	COG0488	(ABC) transporter
KCU58_03440	COG0477	Major facilitator Superfamily
KCU58_03470	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KCU58_03480	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KCU58_03480	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KCU58_03495	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
KCU58_03500	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KCU58_03505	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
KCU58_03530	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
KCU58_03535	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
KCU58_03545	COG2205	protein histidine kinase activity
KCU58_03550	COG0745	RESPONSE REGULATOR receiver
KCU58_03555	COG0277	FAD linked oxidase domain protein
KCU58_03565	COG0792	nuclease activity
KCU58_03600	COG2001	Belongs to the MraZ family
KCU58_03605	COG0275	rRNA processing
KCU58_03610	COG3116	cell division
KCU58_03625	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KCU58_03650	COG1181	Belongs to the D-alanine--D-alanine ligase family
KCU58_03655	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KCU58_03665	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KCU58_03670	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
KCU58_03680	COG0739	heme binding
KCU58_03695	COG0494	nUDIX hydrolase
KCU58_03705	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KCU58_03730	COG2226	methyltransferase
KCU58_03770	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KCU58_03785	COG1090	epimerase
KCU58_03800	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
KCU58_03805	COG0673	inositol 2-dehydrogenase activity
KCU58_03810	COG2823	Periplasmic or secreted lipoprotein
KCU58_03820	COG2202	Pas domain
KCU58_03820	COG2205	protein histidine kinase activity
KCU58_03825	COG0784	Response regulator, receiver
KCU58_03830	COG4191	Histidine kinase
KCU58_03840	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KCU58_03875	COG3250	beta-galactosidase activity
KCU58_03890	COG2188	Transcriptional regulator
KCU58_03895	COG0738	Major facilitator superfamily
KCU58_03900	COG1609	Transcriptional regulator
KCU58_03905	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KCU58_03910	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KCU58_03915	COG0617	tRNA 3'-terminal CCA addition
KCU58_03990	COG2205	protein histidine kinase activity
KCU58_04005	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
KCU58_04010	COG3791	Glutathione-dependent formaldehyde-activating
KCU58_04050	COG0804	urea catabolic process
KCU58_04055	COG1228	amidohydrolase
KCU58_04075	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
KCU58_04100	COG0436	Aminotransferase
KCU58_04105	COG1162	GTPase activity
KCU58_04130	COG2211	Major facilitator Superfamily
KCU58_04140	COG1028	Short-chain dehydrogenase reductase Sdr
KCU58_04145	COG2851	Citrate transporter
KCU58_04160	COG0642	Histidine kinase
KCU58_04180	COG4191	Histidine kinase
KCU58_04190	COG1301	dicarboxylic acid transport
KCU58_04195	COG0281	malic enzyme
KCU58_04195	COG0280	phosphate acetyltransferase
KCU58_04280	COG1560	Kdo2-lipid A biosynthetic process
KCU58_04285	COG1519	Transferase
KCU58_04290	COG1538	Outer membrane efflux protein
KCU58_04295	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
KCU58_04305	COG3706	GGDEF domain
KCU58_04310	COG0473	3-isopropylmalate dehydrogenase activity
KCU58_04315	COG0066	3-isopropylmalate dehydratase activity
KCU58_04325	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KCU58_04335	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KCU58_04355	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KCU58_04360	COG0840	transmembrane signaling receptor activity
KCU58_04380	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
KCU58_04390	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
KCU58_04410	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KCU58_04420	COG0671	phosphoesterase, PA-phosphatase related
KCU58_04435	COG1940	carbohydrate kinase activity
KCU58_04445	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KCU58_04485	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
KCU58_04500	COG1773	rubredoxin
KCU58_04515	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KCU58_04525	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KCU58_04550	COG3079	Belongs to the UPF0149 family
KCU58_04555	COG0006	proline dipeptidase activity
KCU58_04575	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
KCU58_04605	COG0714	Associated with various cellular activities
KCU58_04635	COG1301	dicarboxylic acid transport
KCU58_04640	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KCU58_04665	COG0739	heme binding
KCU58_04670	COG1376	ErfK ybiS ycfS ynhG family protein
KCU58_04695	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
KCU58_04700	COG4149	molybdate abc transporter
KCU58_04705	COG0725	ABC transporter, periplasmic molybdate-binding protein
KCU58_04715	COG0640	Transcriptional regulator
KCU58_04735	COG3047	cAMP biosynthetic process
KCU58_04740	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KCU58_04785	COG0469	pyruvate kinase activity
KCU58_04790	COG3588	fructose-bisphosphate aldolase
KCU58_04795	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
KCU58_04835	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KCU58_04850	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KCU58_04850	COG1648	precorrin-2 dehydrogenase activity
KCU58_04865	COG0784	Response regulator, receiver
KCU58_04865	COG2205	protein histidine kinase activity
KCU58_04865	COG2198	Histidine kinase
KCU58_04870	COG1393	Belongs to the ArsC family
KCU58_04900	COG0175	sulfate reduction
KCU58_04905	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KCU58_04910	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KCU58_04920	COG2895	sulfate adenylyltransferase (ATP) activity
KCU58_04920	COG0529	Catalyzes the synthesis of activated sulfate
KCU58_04925	COG0840	transmembrane signaling receptor activity
KCU58_04965	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KCU58_04985	COG1609	Transcriptional regulator
KCU58_05000	COG0179	Fumarylacetoacetate (FAA) hydrolase
KCU58_05015	COG3273	potassium ion transport
KCU58_05015	COG0471	metal ion transport
KCU58_05025	COG2022	thiamine diphosphate biosynthetic process
KCU58_05050	COG0174	glutamine synthetase
KCU58_05055	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
KCU58_05065	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
KCU58_05080	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KCU58_05105	COG3511	phospholipase C
KCU58_05115	COG0189	ligase activity
KCU58_05125	COG0745	RESPONSE REGULATOR receiver
KCU58_05140	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
KCU58_05205	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KCU58_05205	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
KCU58_05215	COG1262	PFAM Formylglycine-generating sulfatase enzyme
KCU58_05230	COG1174	glycine betaine transport
KCU58_05235	COG1125	glycine betaine transport
KCU58_05245	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KCU58_05250	COG0564	pseudouridine synthase activity
KCU58_05270	COG4993	Dehydrogenase
KCU58_05285	COG3387	PFAM Glycoside hydrolase 15-related
KCU58_05335	COG0542	response to heat
KCU58_05360	COG0019	diaminopimelate decarboxylase activity
KCU58_05365	COG4264	IucA IucC family
KCU58_05370	COG2814	Major facilitator Superfamily
KCU58_05375	COG4264	IucA IucC family
KCU58_05385	COG4772	TonB-dependent receptor
KCU58_05395	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KCU58_05395	COG4651	solute:proton antiporter activity
KCU58_05450	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KCU58_05450	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KCU58_05470	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
KCU58_05510	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KCU58_05515	COG1404	Belongs to the peptidase S8 family
KCU58_05550	COG1295	ribonuclease BN
KCU58_05555	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KCU58_05575	COG0521	Mo-molybdopterin cofactor biosynthetic process
KCU58_05685	COG3209	COG3209 Rhs family protein
KCU58_05740	COG4682	membrane
KCU58_05830	COG3179	chitinase
KCU58_05995	COG3537	Alpha-1,2-mannosidase
KCU58_06015	COG1472	Belongs to the glycosyl hydrolase 3 family
KCU58_06025	COG3525	Glycosyl hydrolase, family 20, catalytic domain
KCU58_06030	COG3858	chitin binding
KCU58_06030	COG1388	LysM domain
KCU58_06050	COG0837	glucose binding
KCU58_06060	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KCU58_06070	COG0494	nUDIX hydrolase
KCU58_06075	COG1218	3'(2'),5'-bisphosphate nucleotidase
KCU58_06080	COG3956	TIGRFAM MazG family protein
KCU58_06085	COG1742	UPF0060 membrane protein
KCU58_06095	COG0330	HflC and HflK could
KCU58_06165	COG2124	cytochrome p450
KCU58_06170	COG2124	cytochrome p450
KCU58_06175	COG1141	Ferredoxin
KCU58_06180	COG1028	Short-chain dehydrogenase reductase Sdr
KCU58_06185	COG2124	cytochrome p450
KCU58_06190	COG0142	geranyltranstransferase activity
KCU58_06195	COG1657	PFAM Prenyltransferase squalene oxidase
KCU58_06205	COG1304	FMN binding
KCU58_06240	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KCU58_06245	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KCU58_06250	COG0463	Glycosyl transferase, family 2
KCU58_06255	COG0517	IMP dehydrogenase activity
KCU58_06260	COG2982	Protein involved in outer membrane biogenesis
KCU58_06265	COG1272	protein, Hemolysin III
KCU58_06270	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KCU58_06280	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KCU58_06285	COG0626	cystathionine gamma-synthase activity
KCU58_06290	COG0527	aspartate kinase activity
KCU58_06290	COG0460	homoserine dehydrogenase
KCU58_06295	COG2267	carboxylic ester hydrolase activity
KCU58_06305	COG1760	l-serine dehydratase
KCU58_06320	COG3038	cytochrome b561
KCU58_06340	COG2814	Major facilitator Superfamily
KCU58_06345	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KCU58_06355	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KCU58_06375	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KCU58_06380	COG0259	pyridoxamine-phosphate oxidase activity
KCU58_06420	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KCU58_06435	COG0519	Catalyzes the synthesis of GMP from XMP
KCU58_06450	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KCU58_06475	COG0840	transmembrane signaling receptor activity
KCU58_06485	COG1113	amino acid transport
KCU58_06505	COG2239	Acts as a magnesium transporter
KCU58_06510	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KCU58_06515	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KCU58_06525	COG1660	Displays ATPase and GTPase activities
KCU58_06535	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KCU58_06550	COG1137	ATPase activity
KCU58_06565	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
KCU58_06610	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KCU58_06635	COG0628	permease
KCU58_06645	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KCU58_06650	COG3178	'Phosphotransferase
KCU58_06665	COG1555	photosystem II stabilization
KCU58_06685	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KCU58_06690	COG1477	protein flavinylation
KCU58_06715	COG4774	siderophore transport
KCU58_06720	COG2146	nitrite reductase [NAD(P)H] activity
KCU58_06730	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KCU58_06735	COG0719	Fe-S assembly protein
KCU58_06740	COG0396	ATPase activity
KCU58_06745	COG0719	Fe-S assembly protein
KCU58_06760	COG0693	protein deglycase activity
KCU58_06775	COG0739	heme binding
KCU58_06790	COG1764	response to oxidative stress
KCU58_06800	COG0384	phenazine biosynthesis protein PhzF
KCU58_06805	COG0527	aspartate kinase activity
KCU58_06830	COG0142	geranyltranstransferase activity
KCU58_06835	COG0629	single-stranded DNA binding
KCU58_06855	COG3104	oligopeptide transport
KCU58_06860	COG1297	OPT oligopeptide transporter protein
KCU58_06865	COG0823	Involved in the tonB-independent uptake of proteins
KCU58_06865	COG1506	peptidase
KCU58_06890	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KCU58_06895	COG2879	small protein
KCU58_06900	COG1966	Carbon starvation protein
KCU58_06935	COG2211	Major facilitator Superfamily
KCU58_06945	COG2801	Transposase and inactivated derivatives
KCU58_06970	COG0835	chemotaxis
KCU58_06975	COG0840	transmembrane signaling receptor activity
KCU58_06980	COG0840	transmembrane signaling receptor activity
KCU58_06985	COG0840	transmembrane signaling receptor activity
KCU58_06990	COG0643	Histidine kinase
KCU58_06990	COG2198	Histidine kinase
KCU58_07000	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KCU58_07020	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
KCU58_07030	COG2205	protein histidine kinase activity
KCU58_07065	COG0735	belongs to the Fur family
KCU58_07105	COG1529	Aldehyde oxidase and xanthine dehydrogenase
KCU58_07110	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
KCU58_07115	COG2080	2 iron, 2 sulfur cluster binding
KCU58_07225	COG1187	pseudouridine synthase activity
KCU58_07250	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KCU58_07270	COG1132	(ABC) transporter
KCU58_07365	COG1981	membrane
KCU58_07390	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KCU58_07395	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KCU58_07405	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KCU58_07415	COG0750	zinc metalloprotease
KCU58_07420	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
KCU58_07425	COG0575	Belongs to the CDS family
KCU58_07430	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KCU58_07440	COG0528	UMP kinase activity
KCU58_07450	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KCU58_07490	COG0024	Methionine aminopeptidase
KCU58_07505	COG1393	Belongs to the ArsC family
KCU58_07510	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KCU58_07520	COG0367	asparagine synthase
KCU58_07560	COG1566	PFAM secretion protein HlyD family protein
KCU58_07565	COG2814	Major facilitator Superfamily
KCU58_07600	COG0557	exoribonuclease II activity
KCU58_07610	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KCU58_07630	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KCU58_07650	COG0704	Plays a role in the regulation of phosphate uptake
KCU58_07660	COG0581	inorganic phosphate transmembrane transporter activity
KCU58_07670	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KCU58_07675	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KCU58_07695	COG0659	secondary active sulfate transmembrane transporter activity
KCU58_07705	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KCU58_07715	COG1024	Enoyl-CoA hydratase
KCU58_07775	COG5002	protein histidine kinase activity
KCU58_07775	COG0784	Response regulator, receiver
KCU58_07775	COG2205	protein histidine kinase activity
KCU58_07780	COG2733	membrane
KCU58_07800	COG0686	Belongs to the AlaDH PNT family
KCU58_07805	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KCU58_07810	COG1917	Cupin 2, conserved barrel domain protein
KCU58_07810	COG1396	sequence-specific DNA binding
KCU58_07815	COG1012	belongs to the aldehyde dehydrogenase family
KCU58_07835	COG2223	nitrite transmembrane transporter activity
KCU58_07845	COG0243	molybdopterin cofactor binding
KCU58_07860	COG0477	Major facilitator Superfamily
KCU58_07870	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KCU58_07875	COG0174	glutamine synthetase
KCU58_07880	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
KCU58_07885	COG0174	glutamine synthetase
KCU58_07900	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
KCU58_07920	COG3842	ATPase activity
KCU58_07925	COG1176	ABC-type spermidine putrescine transport system, permease component I
KCU58_07930	COG1177	transmembrane transport
KCU58_07935	COG1012	belongs to the aldehyde dehydrogenase family
KCU58_07950	COG4535	Mg2 and Co2 transporter CorC
KCU58_07965	COG1702	phosphate starvation-inducible protein PhoH
KCU58_07980	COG0741	lytic transglycosylase activity
KCU58_07985	COG0723	plastoquinol--plastocyanin reductase activity
KCU58_07990	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KCU58_08000	COG2857	Cytochrome c1
KCU58_08005	COG0625	glutathione transferase activity
KCU58_08010	COG2969	positive regulation of protein catabolic process
KCU58_08050	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
KCU58_08055	COG1028	Short-chain dehydrogenase reductase Sdr
KCU58_08060	COG2095	MarC family integral membrane protein
KCU58_08070	COG1611	Belongs to the LOG family
KCU58_08075	COG3275	phosphorelay sensor kinase activity
KCU58_08120	COG0556	nucleotide-excision repair
KCU58_08140	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KCU58_08145	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KCU58_08155	COG2902	Dehydrogenase
KCU58_08215	COG2925	Exonuclease
KCU58_08225	COG3844	kynureninase activity
KCU58_08235	COG0662	Cupin 2, conserved barrel domain protein
KCU58_08240	COG0288	reversible hydration of carbon dioxide
KCU58_08285	COG2197	response regulator
KCU58_08310	COG0316	Belongs to the HesB IscA family
KCU58_08345	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KCU58_08350	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KCU58_08355	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
KCU58_08365	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
KCU58_08385	COG1309	transcriptional regulator
KCU58_08400	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
KCU58_08415	COG1228	amidohydrolase
KCU58_08430	COG4221	oxidoreductase activity
KCU58_08470	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KCU58_08475	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KCU58_08480	COG0077	Prephenate dehydratase
KCU58_08480	COG1605	Chorismate mutase
KCU58_08505	COG0583	DNA-binding transcription factor activity
KCU58_08555	COG0577	efflux transmembrane transporter activity
KCU58_08555	COG1136	(ABC) transporter
KCU58_08585	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KCU58_08585	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KCU58_08590	COG1105	Belongs to the carbohydrate kinase PfkB family
KCU58_08595	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KCU58_08595	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
KCU58_08600	COG1609	Transcriptional regulator
KCU58_08610	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
KCU58_08615	COG0069	glutamate synthase activity
KCU58_08650	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KCU58_08665	COG1253	flavin adenine dinucleotide binding
KCU58_08675	COG0306	phosphate transporter
KCU58_08720	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
KCU58_08725	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
KCU58_08740	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
KCU58_08750	COG1238	metal cluster binding
KCU58_08765	COG1534	Rna-binding protein
KCU58_08770	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
KCU58_08775	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KCU58_08780	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KCU58_08785	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KCU58_08795	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KCU58_08800	COG1546	Belongs to the CinA family
KCU58_08805	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
KCU58_08810	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KCU58_08815	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KCU58_08820	COG2137	regulation of response to DNA damage stimulus
KCU58_08830	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
KCU58_08855	COG1741	Belongs to the pirin family
KCU58_08860	COG0583	DNA-binding transcription factor activity
KCU58_08880	COG0352	thiamine-phosphate diphosphorylase activity
KCU58_08880	COG0351	phosphomethylpyrimidine kinase
KCU58_08925	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
KCU58_08930	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KCU58_08940	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KCU58_08950	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
KCU58_08955	COG3734	2-keto-3-deoxy-galactonokinase
KCU58_08970	COG0800	Aldolase
KCU58_09005	COG2205	protein histidine kinase activity
KCU58_09005	COG2198	Histidine kinase
KCU58_09005	COG0784	Response regulator, receiver
KCU58_09010	COG1024	Enoyl-CoA hydratase
KCU58_09015	COG0318	PFAM AMP-dependent synthetase and ligase
KCU58_09080	COG0840	transmembrane signaling receptor activity
KCU58_09090	COG0840	transmembrane signaling receptor activity
KCU58_09100	COG0835	chemotaxis
KCU58_09110	COG0840	transmembrane signaling receptor activity
KCU58_09120	COG0840	transmembrane signaling receptor activity
KCU58_09125	COG0840	transmembrane signaling receptor activity
KCU58_09130	COG0840	transmembrane signaling receptor activity
KCU58_09140	COG0840	transmembrane signaling receptor activity
KCU58_09150	COG0840	transmembrane signaling receptor activity
KCU58_09155	COG0840	transmembrane signaling receptor activity
KCU58_09160	COG0840	transmembrane signaling receptor activity
KCU58_09165	COG0840	transmembrane signaling receptor activity
KCU58_09180	COG0745	RESPONSE REGULATOR receiver
KCU58_09190	COG0835	chemotaxis
KCU58_09195	COG1192	Involved in chromosome partitioning
KCU58_09205	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KCU58_09210	COG0784	Response regulator, receiver
KCU58_09210	COG0643	Histidine kinase
KCU58_09210	COG2198	Histidine kinase
KCU58_09215	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
KCU58_09260	COG1684	flagellar biosynthetic protein fliR
KCU58_09265	COG1987	bacterial-type flagellum assembly
KCU58_09275	COG3190	flagellar
KCU58_09325	COG1677	Flagellar hook-basal body complex protein FliE
KCU58_09360	COG1028	Short-chain dehydrogenase reductase Sdr
KCU58_09370	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KCU58_09390	COG2201	protein-glutamate methylesterase activity
KCU58_09400	COG2197	response regulator
KCU58_09420	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
KCU58_09425	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KCU58_09435	COG4786	Flagellar basal body rod
KCU58_09435	COG1256	bacterial-type flagellum assembly
KCU58_09435	COG1256	bacterial-type flagellum assembly
KCU58_09435	COG4786	Flagellar basal body rod
KCU58_09450	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
KCU58_09465	COG1749	Flagellar hook protein flgE
KCU58_09475	COG1558	bacterial-type flagellum-dependent cell motility
KCU58_09485	COG0835	chemotaxis
KCU58_09485	COG0784	Response regulator, receiver
KCU58_09545	COG2915	High frequency lysogenization protein hflD homolog
KCU58_09550	COG0482	sulfurtransferase activity
KCU58_09570	COG0542	response to heat
KCU58_09580	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
KCU58_09590	COG0492	ferredoxin-NADP+ reductase activity
KCU58_09595	COG1674	ftsk spoiiie
KCU58_09615	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KCU58_09620	COG0038	chloride channel
KCU58_09675	COG1595	DNA-templated transcription, initiation
KCU58_09695	COG3038	cytochrome b561
KCU58_09725	COG2244	polysaccharide biosynthetic process
KCU58_09745	COG4106	trans-aconitate 2-methyltransferase activity
KCU58_09765	COG0438	transferase activity, transferring glycosyl groups
KCU58_09770	COG0438	transferase activity, transferring glycosyl groups
KCU58_09795	COG1132	(ABC) transporter
KCU58_09820	COG1530	ribonuclease E activity
KCU58_09835	COG0428	transporter
KCU58_09850	COG0316	Belongs to the HesB IscA family
KCU58_09850	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
KCU58_09870	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KCU58_09890	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KCU58_09895	COG2957	Belongs to the agmatine deiminase family
KCU58_09905	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KCU58_09910	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
KCU58_09915	COG0539	negative regulation of cytoplasmic translation
KCU58_09920	COG0776	regulation of translation
KCU58_09930	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
KCU58_09935	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KCU58_09945	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KCU58_09950	COG0183	Belongs to the thiolase family
KCU58_09955	COG1024	Enoyl-CoA hydratase
KCU58_09955	COG1250	3-hydroxyacyl-CoA dehydrogenase
KCU58_09970	COG0820	rRNA (adenine-C2-)-methyltransferase activity
KCU58_09980	COG1426	Protein conserved in bacteria
KCU58_09990	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KCU58_10000	COG0746	molybdenum cofactor guanylyltransferase activity
KCU58_10010	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KCU58_10015	COG0475	glutathione-regulated potassium exporter activity
KCU58_10015	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KCU58_10035	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KCU58_10045	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KCU58_10045	COG0519	Catalyzes the synthesis of GMP from XMP
KCU58_10050	COG0582	viral genome integration into host DNA
KCU58_10160	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KCU58_10165	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
KCU58_10175	COG0505	Belongs to the CarA family
KCU58_10185	COG2258	MOSC domain
KCU58_10190	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KCU58_10210	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KCU58_10220	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KCU58_10225	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
KCU58_10260	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KCU58_10275	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KCU58_10285	COG1663	tetraacyldisaccharide 4'-kinase activity
KCU58_10290	COG1132	(ABC) transporter
KCU58_10300	COG0811	peptide transport
KCU58_10320	COG4591	ABC-type transport system involved in lipoprotein release permease component
KCU58_10330	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
KCU58_10335	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KCU58_10345	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
KCU58_10350	COG2009	succinate dehydrogenase
KCU58_10370	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KCU58_10385	COG0129	dihydroxy-acid dehydratase activity
KCU58_10400	COG0395	ABC-type sugar transport system, permease component
KCU58_10435	COG2350	Protein conserved in bacteria
KCU58_10440	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KCU58_10445	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KCU58_10450	COG1187	pseudouridine synthase activity
KCU58_10475	COG0436	Aminotransferase
KCU58_10480	COG4133	protoheme IX ABC transporter activity
KCU58_10525	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KCU58_10530	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KCU58_10535	COG4988	ABC transporter
KCU58_10545	COG1294	oxidase, subunit
KCU58_10575	COG2801	Transposase and inactivated derivatives
KCU58_10580	COG2963	transposase activity
KCU58_10595	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
KCU58_10600	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
KCU58_10615	COG1024	Enoyl-CoA hydratase
KCU58_10625	COG1024	Enoyl-CoA hydratase
KCU58_10630	COG1024	Enoyl-CoA hydratase
KCU58_10670	COG0346	lactoylglutathione lyase activity
KCU58_10680	COG1304	FMN binding
KCU58_10685	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KCU58_10690	COG1649	PFAM Uncharacterised BCR, COG1649
KCU58_10840	COG1196	nuclear chromosome segregation
KCU58_10920	COG3728	DNA packaging
KCU58_10920	COG5484	DNA packaging
KCU58_10990	COG0270	DNA (cytosine-5-)-methyltransferase activity
KCU58_11005	COG0305	Participates in initiation and elongation during chromosome replication
KCU58_11155	COG0784	Response regulator, receiver
KCU58_11155	COG2205	protein histidine kinase activity
KCU58_11160	COG2183	response to ionizing radiation
KCU58_11165	COG0784	Response regulator, receiver
KCU58_11165	COG4191	Histidine kinase
KCU58_11175	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KCU58_11175	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
KCU58_11195	COG3243	poly(R)-hydroxyalkanoic acid synthase
KCU58_11205	COG1183	phosphatidylcholine synthase activity
KCU58_11210	COG1028	Short-chain dehydrogenase reductase Sdr
KCU58_11225	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
KCU58_11235	COG0668	transmembrane transport
KCU58_11240	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
KCU58_11255	COG1914	H( )-stimulated, divalent metal cation uptake system
KCU58_11265	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
KCU58_11270	COG1501	Belongs to the glycosyl hydrolase 31 family
KCU58_11275	COG2963	transposase activity
KCU58_11330	COG1487	ribonuclease activity
KCU58_11335	COG4691	Plasmid stability protein
KCU58_11365	COG1960	acyl-CoA dehydrogenase activity
KCU58_11370	COG2226	methyltransferase
KCU58_11375	COG0646	methionine synthase
KCU58_11375	COG1410	methionine synthase
KCU58_11380	COG0646	methionine synthase
KCU58_11380	COG1410	methionine synthase
KCU58_11400	COG2900	Belongs to the SlyX family
KCU58_11415	COG0386	Belongs to the glutathione peroxidase family
KCU58_11425	COG1725	Transcriptional regulator
KCU58_11430	COG1131	(ABC) transporter
KCU58_11475	COG2885	chlorophyll binding
KCU58_11480	COG2850	peptidyl-arginine hydroxylation
KCU58_11530	COG1132	(ABC) transporter
KCU58_11540	COG0287	Prephenate dehydrogenase
KCU58_11540	COG1605	Chorismate mutase
KCU58_11545	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
KCU58_11550	COG0484	heat shock protein binding
KCU58_11555	COG0443	Heat shock 70 kDa protein
KCU58_11560	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KCU58_11565	COG1420	regulation of RNA biosynthetic process
KCU58_11570	COG0497	DNA recombination
KCU58_11575	COG0735	belongs to the Fur family
KCU58_11580	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KCU58_11590	COG2867	negative regulation of translational initiation
KCU58_11595	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
KCU58_11600	COG1404	Belongs to the peptidase S8 family
KCU58_11635	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KCU58_11650	COG0583	DNA-binding transcription factor activity
KCU58_11665	COG0415	Belongs to the DNA photolyase family
KCU58_11670	COG0305	Participates in initiation and elongation during chromosome replication
KCU58_11680	COG1960	acyl-CoA dehydrogenase activity
KCU58_11695	COG0084	hydrolase, TatD family'
KCU58_11700	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KCU58_11750	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KCU58_11775	COG0386	Belongs to the glutathione peroxidase family
KCU58_11790	COG1846	Transcriptional regulator
KCU58_11830	COG1472	Belongs to the glycosyl hydrolase 3 family
KCU58_11840	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KCU58_11845	COG4290	ribonuclease
KCU58_11855	COG0488	(ABC) transporter
KCU58_11860	COG0513	Belongs to the DEAD box helicase family
KCU58_11885	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
KCU58_11890	COG0657	acetylesterase activity
KCU58_11895	COG0625	glutathione transferase activity
KCU58_11905	COG0564	pseudouridine synthase activity
KCU58_11910	COG4681	YaeQ
KCU58_11915	COG2081	HI0933 family
KCU58_11935	COG1028	Short-chain dehydrogenase reductase Sdr
KCU58_11955	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KCU58_11960	COG0860	N-Acetylmuramoyl-L-alanine amidase
KCU58_11965	COG0802	atpase or kinase
KCU58_11970	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
KCU58_11970	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KCU58_11975	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KCU58_12020	COG1960	acyl-CoA dehydrogenase activity
KCU58_12030	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KCU58_12050	COG0438	transferase activity, transferring glycosyl groups
KCU58_12060	COG0438	transferase activity, transferring glycosyl groups
KCU58_12065	COG0438	transferase activity, transferring glycosyl groups
KCU58_12115	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KCU58_12120	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KCU58_12130	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KCU58_12165	COG1024	Enoyl-CoA hydratase
KCU58_12180	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KCU58_12200	COG0277	FAD linked oxidase domain protein
KCU58_12205	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KCU58_12220	COG0531	amino acid
KCU58_12225	COG0531	amino acid
KCU58_12230	COG0235	Class ii aldolase
KCU58_12235	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
KCU58_12240	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
KCU58_12260	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KCU58_12260	COG0140	phosphoribosyl-ATP diphosphatase activity
KCU58_12275	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KCU58_12290	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KCU58_12295	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
KCU58_12305	COG0124	histidyl-tRNA synthetase
KCU58_12310	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KCU58_12320	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KCU58_12330	COG2951	lytic endotransglycosylase activity
KCU58_12335	COG0083	homoserine kinase activity
KCU58_12340	COG0527	aspartate kinase activity
KCU58_12340	COG0460	homoserine dehydrogenase
KCU58_12355	COG1012	belongs to the aldehyde dehydrogenase family
KCU58_12370	COG0167	dihydroorotate dehydrogenase activity
KCU58_12375	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KCU58_12400	COG0671	phosphoesterase, PA-phosphatase related
KCU58_12415	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
KCU58_12485	COG0166	Belongs to the GPI family
KCU58_12500	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
KCU58_12510	COG0617	tRNA 3'-terminal CCA addition
KCU58_12530	COG0860	N-Acetylmuramoyl-L-alanine amidase
KCU58_12535	COG0477	Major facilitator Superfamily
KCU58_12540	COG2115	Belongs to the xylose isomerase family
KCU58_12545	COG1070	Carbohydrate kinase
KCU58_12565	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KCU58_12585	COG0165	Argininosuccinate lyase
KCU58_12590	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KCU58_12600	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
KCU58_12605	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KCU58_12610	COG0137	argininosuccinate synthase activity
KCU58_12615	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KCU58_12630	COG2166	iron-sulfur cluster assembly
KCU58_12700	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
KCU58_12740	COG0402	S-adenosylhomocysteine deaminase activity
KCU58_12745	COG3548	integral membrane protein
KCU58_12755	COG1509	lysine 2,3-aminomutase activity
KCU58_12760	COG2203	Gaf domain
KCU58_12760	COG3706	GGDEF domain
KCU58_12760	COG4251	negative regulation of phosphorylation
KCU58_12760	COG5001	Diguanylate cyclase
KCU58_12785	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KCU58_12790	COG1862	Preprotein translocase
KCU58_12800	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KCU58_12810	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KCU58_12820	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KCU58_12825	COG3291	Pkd domain containing protein
KCU58_12830	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KCU58_12835	COG0405	Gamma-glutamyltransferase
KCU58_12840	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
KCU58_12855	COG0742	ribosomal rna small subunit methyltransferase
KCU58_12880	COG4771	TonB-dependent receptor
KCU58_12890	COG3507	Belongs to the glycosyl hydrolase 43 family
KCU58_12925	COG0531	amino acid
KCU58_12940	COG0006	proline dipeptidase activity
KCU58_12950	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KCU58_12965	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KCU58_12970	COG3938	Belongs to the proline racemase family
KCU58_12980	COG0552	protein localization to endoplasmic reticulum
KCU58_12985	COG1194	a g-specific adenine glycosylase
KCU58_13035	COG0835	chemotaxis
KCU58_13040	COG0840	transmembrane signaling receptor activity
KCU58_13045	COG0840	transmembrane signaling receptor activity
KCU58_13065	COG5001	Diguanylate cyclase
KCU58_13065	COG3300	MHYT domain
KCU58_13070	COG1185	polyribonucleotide nucleotidyltransferase activity
KCU58_13095	COG0195	Participates in both transcription termination and antitermination
KCU58_13110	COG1007	ATP synthesis coupled electron transport
KCU58_13145	COG1034	ATP synthesis coupled electron transport
KCU58_13150	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
KCU58_13155	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
KCU58_13160	COG0649	NAD binding
KCU58_13165	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KCU58_13175	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KCU58_13195	COG1028	Short-chain dehydrogenase reductase Sdr
KCU58_13215	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KCU58_13260	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KCU58_13275	COG2890	protein-(glutamine-N5) methyltransferase activity
KCU58_13285	COG0688	phosphatidylethanolamine metabolic process
KCU58_13290	COG0741	lytic transglycosylase activity
KCU58_13295	COG0433	COG0433 Predicted ATPase
KCU58_13300	COG0494	nUDIX hydrolase
KCU58_13315	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KCU58_13335	COG1714	RDD family
KCU58_13340	COG0717	Belongs to the dCTP deaminase family
KCU58_13345	COG0489	protein tyrosine kinase activity
KCU58_13355	COG4771	TonB-dependent receptor
KCU58_13360	COG4771	TonB-dependent receptor
KCU58_13365	COG0457	Tetratricopeptide repeat
KCU58_13380	COG3590	peptidase
KCU58_13430	COG0697	spore germination
KCU58_13450	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KCU58_13455	COG2311	Membrane
KCU58_13460	COG1047	Peptidyl-prolyl cis-trans
KCU58_13465	COG0791	NLP P60 protein
KCU58_13470	COG0791	NLP P60 protein
KCU58_13485	COG1607	acyl-coa hydrolase
KCU58_13495	COG1301	dicarboxylic acid transport
KCU58_13500	COG1785	Belongs to the alkaline phosphatase family
KCU58_13510	COG0037	tRNA processing
KCU58_13515	COG1722	exodeoxyribonuclease VII activity
KCU58_13520	COG0142	geranyltranstransferase activity
KCU58_13530	COG1858	cytochrome C peroxidase
KCU58_13555	COG0515	serine threonine protein kinase
KCU58_13555	COG2815	serine threonine protein kinase
KCU58_13560	COG0631	protein serine/threonine phosphatase activity
KCU58_13650	COG0312	modulator of DNA gyrase
KCU58_13660	COG0312	modulator of DNA gyrase
KCU58_13680	COG2968	Membrane
KCU58_13695	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KCU58_13710	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KCU58_13725	COG0495	leucyl-tRNA aminoacylation
KCU58_13735	COG3118	belongs to the thioredoxin family
KCU58_13755	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
KCU58_13765	COG2040	homocysteine
KCU58_13770	COG0833	amino acid
KCU58_13780	COG0346	lactoylglutathione lyase activity
KCU58_13800	COG2878	Part of a membrane complex involved in electron transport
KCU58_13815	COG1595	DNA-templated transcription, initiation
KCU58_13840	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KCU58_13860	COG0251	oxidation-reduction process
KCU58_13870	COG0392	lysyltransferase activity
KCU58_13870	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KCU58_13900	COG2814	Major facilitator Superfamily
KCU58_13910	COG1902	pentaerythritol trinitrate reductase activity
KCU58_13915	COG2824	Alkylphosphonate utilization operon protein PhnA
KCU58_13920	COG1047	Peptidyl-prolyl cis-trans
KCU58_13925	COG1077	Cell shape determining protein MreB Mrl
KCU58_13960	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KCU58_13970	COG1451	nucleotide metabolic process
KCU58_13995	COG2205	protein histidine kinase activity
KCU58_13995	COG2198	Histidine kinase
KCU58_13995	COG0784	Response regulator, receiver
KCU58_14005	COG2186	Transcriptional regulator
KCU58_14010	COG3250	beta-galactosidase activity
KCU58_14075	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
KCU58_14075	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
KCU58_14075	COG1703	isobutyryl-CoA mutase activity
KCU58_14110	COG0183	Belongs to the thiolase family
KCU58_14120	COG0443	Heat shock 70 kDa protein
KCU58_14150	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
KCU58_14150	COG1793	dna ligase
KCU58_14155	COG1793	dna ligase
KCU58_14155	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
KCU58_14160	COG1201	RNA secondary structure unwinding
KCU58_14170	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KCU58_14175	COG1278	Cold shock
KCU58_14180	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
KCU58_14185	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
KCU58_14190	COG1472	Belongs to the glycosyl hydrolase 3 family
KCU58_14200	COG2954	triphosphatase activity
KCU58_14210	COG0745	RESPONSE REGULATOR receiver
KCU58_14220	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KCU58_14235	COG0681	Belongs to the peptidase S26 family
KCU58_14240	COG0481	GTPase activity
KCU58_14245	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KCU58_14275	COG2855	membrane
KCU58_14290	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KCU58_14310	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
KCU58_14320	COG0534	Mate efflux family protein
KCU58_14325	COG0335	large ribosomal subunit rRNA binding
KCU58_14330	COG0336	Belongs to the RNA methyltransferase TrmD family
KCU58_14335	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KCU58_14350	COG2070	2-Nitropropane dioxygenase
KCU58_14355	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KCU58_14370	COG3534	alpha-L-arabinofuranosidase
KCU58_14380	COG0475	glutathione-regulated potassium exporter activity
KCU58_14390	COG0625	glutathione transferase activity
KCU58_14395	COG1082	Xylose isomerase domain protein TIM barrel
KCU58_14405	COG1172	Belongs to the binding-protein-dependent transport system permease family
KCU58_14410	COG1172	Belongs to the binding-protein-dependent transport system permease family
KCU58_14415	COG1129	ABC transporter
KCU58_14420	COG1879	ABC-type sugar transport system periplasmic component
KCU58_14425	COG1012	belongs to the aldehyde dehydrogenase family
KCU58_14445	COG0129	dihydroxy-acid dehydratase activity
KCU58_14470	COG2207	Transcriptional regulator
KCU58_14490	COG1317	bacterial-type flagellum organization
KCU58_14515	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KCU58_14540	COG4794	Type iii secretion
KCU58_14570	COG0745	RESPONSE REGULATOR receiver
KCU58_14600	COG3152	Membrane
KCU58_14610	COG0156	8-amino-7-oxononanoate synthase activity
KCU58_14620	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
KCU58_14625	COG1845	cytochrome c oxidase, subunit III
KCU58_14630	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KCU58_14650	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
KCU58_14665	COG0196	riboflavin kinase activity
KCU58_14685	COG0728	peptidoglycan biosynthetic process
KCU58_14700	COG0211	Belongs to the bacterial ribosomal protein bL27 family
KCU58_14705	COG0261	This protein binds to 23S rRNA in the presence of protein L20
KCU58_14710	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KCU58_14715	COG0824	Thioesterase
KCU58_14725	COG1024	Enoyl-CoA hydratase
KCU58_14730	COG1946	Acyl-CoA thioesterase
KCU58_14740	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KCU58_14745	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
KCU58_14810	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KCU58_14855	COG1643	Atp-dependent helicase
KCU58_14860	COG0783	Belongs to the Dps family
KCU58_14865	COG0514	ATP-dependent DNA helicase (RecQ)
KCU58_14885	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KCU58_14890	COG0602	queuosine metabolic process
KCU58_14900	COG2885	chlorophyll binding
KCU58_14915	COG0848	biopolymer transport protein
KCU58_14925	COG0824	Thioesterase
KCU58_14930	COG2255	four-way junction helicase activity
KCU58_14935	COG3158	transport of potassium into the cell
KCU58_14940	COG0632	four-way junction helicase activity
KCU58_14950	COG0217	transcriptional regulatory protein
KCU58_14990	COG3142	Participates in the control of copper homeostasis
KCU58_14995	COG1446	asparaginase
KCU58_15015	COG2201	protein-glutamate methylesterase activity
KCU58_15020	COG2198	Histidine kinase
KCU58_15020	COG0784	Response regulator, receiver
KCU58_15020	COG0643	Histidine kinase
KCU58_15025	COG0840	transmembrane signaling receptor activity
KCU58_15030	COG0835	chemotaxis
KCU58_15045	COG0189	ligase activity
KCU58_15065	COG1199	ATP-dependent helicase activity
KCU58_15075	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KCU58_15080	COG1216	Glycosyl transferase, family 2
KCU58_15085	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KCU58_15105	COG4585	Histidine kinase
KCU58_15115	COG0850	regulation of cytokinetic process
KCU58_15120	COG2894	cell division
KCU58_15125	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
KCU58_15135	COG2205	protein histidine kinase activity
KCU58_15140	COG0745	RESPONSE REGULATOR receiver
KCU58_15150	COG2194	sulfuric ester hydrolase activity
KCU58_15170	COG2814	Major facilitator Superfamily
KCU58_15195	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KCU58_15195	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KCU58_15205	COG0753	catalase activity
KCU58_15215	COG4106	trans-aconitate 2-methyltransferase activity
KCU58_15230	COG1063	alcohol dehydrogenase
KCU58_15240	COG3459	Glycosyltransferase 36 associated
KCU58_15300	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KCU58_15310	COG0330	HflC and HflK could
KCU58_15315	COG0330	HflC and HflK could
KCU58_15320	COG0604	alcohol dehydrogenase
KCU58_15340	COG0678	peroxiredoxin activity
KCU58_15350	COG4953	penicillin-binding protein 1C
KCU58_15370	COG2373	Large extracellular alpha-helical protein
KCU58_15395	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KCU58_15410	COG0372	Belongs to the citrate synthase family
KCU58_15415	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KCU58_15430	COG0587	DNA-directed DNA polymerase activity
KCU58_15465	COG2161	toxin-antitoxin pair type II binding
KCU58_15470	COG4115	mRNA cleavage
KCU58_15490	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KCU58_15495	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KCU58_15500	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KCU58_15510	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KCU58_15515	COG1028	Short-chain dehydrogenase reductase Sdr
KCU58_15520	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KCU58_15525	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KCU58_15535	COG1399	metal-binding, possibly nucleic acid-binding protein
KCU58_15560	COG0714	Associated with various cellular activities
KCU58_15580	COG0537	adenosine 5'-monophosphoramidase activity
KCU58_15620	COG0314	molybdopterin synthase activity
KCU58_15625	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
KCU58_15630	COG0315	cyclic pyranopterin monophosphate synthase activity
KCU58_15640	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KCU58_15645	COG1234	tRNA 3'-trailer cleavage
KCU58_15655	COG0859	PFAM glycosyl transferase family 9
KCU58_15675	COG0631	protein serine/threonine phosphatase activity
KCU58_15695	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KCU58_15700	COG1388	LysM domain
KCU58_15700	COG3942	CHAP domain
KCU58_15735	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KCU58_15745	COG0544	peptidyl-prolyl cis-trans isomerase activity
KCU58_15785	COG0473	3-isopropylmalate dehydrogenase activity
KCU58_15800	COG4783	chaperone-mediated protein folding
KCU58_15815	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KCU58_15820	COG0248	Ppx GppA phosphatase
KCU58_15825	COG0438	transferase activity, transferring glycosyl groups
KCU58_15835	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KCU58_15845	COG3291	Pkd domain containing protein
KCU58_15850	COG2833	Protein of unknown function (DUF455)
KCU58_15870	COG0285	dihydrofolate synthase activity
KCU58_15875	COG0588	phosphoglycerate mutase activity
KCU58_15895	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
KCU58_15900	COG4208	sulfate ABC transporter
KCU58_15905	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
KCU58_15910	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
KCU58_15915	COG0156	8-amino-7-oxononanoate synthase activity
KCU58_15930	COG2885	chlorophyll binding
KCU58_15940	COG2814	Major facilitator Superfamily
KCU58_15955	COG0667	Aldo Keto reductase
KCU58_15965	COG1902	pentaerythritol trinitrate reductase activity
KCU58_15965	COG0446	pyridine nucleotide-disulphide oxidoreductase
KCU58_16010	COG0625	glutathione transferase activity
KCU58_16025	COG0039	L-malate dehydrogenase activity
KCU58_16035	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KCU58_16040	COG1217	gtp-binding protein TYPA
KCU58_16055	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
KCU58_16065	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
KCU58_16070	COG0203	ribosomal protein L17
KCU58_16095	COG0201	protein transport
KCU58_16105	COG1841	ribosomal large subunit assembly
KCU58_16135	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KCU58_16140	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KCU58_16150	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KCU58_16155	COG0255	Belongs to the universal ribosomal protein uL29 family
KCU58_16180	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KCU58_16185	COG0089	rRNA binding
KCU58_16190	COG0088	Forms part of the polypeptide exit tunnel
KCU58_16200	COG0051	transcription antitermination factor activity, RNA binding
KCU58_16205	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KCU58_16210	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KCU58_16225	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KCU58_16235	COG0222	ribosome binding
KCU58_16250	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KCU58_16255	COG0250	Participates in transcription elongation, termination and antitermination
KCU58_16260	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KCU58_16270	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KCU58_16290	COG0012	GTP binding
KCU58_16295	COG0193	aminoacyl-tRNA hydrolase activity
KCU58_16305	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KCU58_16315	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KCU58_16330	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
KCU58_16335	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KCU58_16385	COG0488	(ABC) transporter
KCU58_16425	COG3634	alkyl hydroperoxide reductase activity
KCU58_16430	COG0583	DNA-binding transcription factor activity
KCU58_16440	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KCU58_16445	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KCU58_16475	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KCU58_16480	COG0697	spore germination
KCU58_16520	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KCU58_16525	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KCU58_16535	COG2096	Adenosyltransferase
KCU58_16545	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
KCU58_16550	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KCU58_16555	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
KCU58_16560	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KCU58_16565	COG2967	ApaG domain
KCU58_16570	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KCU58_16630	COG2188	Transcriptional regulator
KCU58_16640	COG1450	Type ii and iii secretion system protein
KCU58_16655	COG3166	PFAM Fimbrial assembly family protein
KCU58_16660	COG3156	type II secretion system protein K
KCU58_16665	COG4795	General secretion pathway protein
KCU58_16670	COG2165	general secretion pathway protein
KCU58_16675	COG4970	Tfp pilus assembly protein FimT
KCU58_16680	COG2165	general secretion pathway protein
KCU58_16685	COG1459	type II secretion system
KCU58_16690	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KCU58_16695	COG1404	Belongs to the peptidase S8 family
KCU58_16700	COG5295	Hep Hag repeat protein
KCU58_16710	COG0840	transmembrane signaling receptor activity
KCU58_16715	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KCU58_16715	COG0047	phosphoribosylformylglycinamidine synthase activity
KCU58_16720	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KCU58_16725	COG4974	Belongs to the 'phage' integrase family
KCU58_16750	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KCU58_16755	COG2927	DNA polymerase III (CHI subunit)
KCU58_16790	COG1183	phosphatidylcholine synthase activity
KCU58_16800	COG0442	prolyl-tRNA aminoacylation
KCU58_16815	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
KCU58_16820	COG1127	ABC transporter
KCU58_16825	COG3218	ABC-type transport auxiliary lipoprotein component
KCU58_16825	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
KCU58_16855	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KCU58_16860	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KCU58_16865	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
KCU58_16865	COG0662	Cupin 2, conserved barrel domain protein
KCU58_16890	COG2086	electron transfer activity
KCU58_16905	COG0546	phosphoglycolate phosphatase activity
KCU58_16905	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
KCU58_16910	COG0277	FAD linked oxidase domain protein
KCU58_16915	COG0300	oxidoreductase activity
KCU58_16940	COG0493	'glutamate synthase
KCU58_16980	COG1216	Glycosyl transferase, family 2
KCU58_16980	COG0438	transferase activity, transferring glycosyl groups
KCU58_16985	COG1216	Glycosyl transferase, family 2
KCU58_16985	COG0438	transferase activity, transferring glycosyl groups
KCU58_16990	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KCU58_17005	COG0626	cystathionine gamma-synthase activity
KCU58_17035	COG0625	glutathione transferase activity
KCU58_17045	COG0513	Belongs to the DEAD box helicase family
KCU58_17050	COG0720	synthase
KCU58_17060	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
KCU58_17065	COG1956	GAF domain-containing protein
KCU58_17075	COG4206	TonB-dependent receptor
KCU58_17080	COG0546	phosphoglycolate phosphatase activity
KCU58_17085	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KCU58_17105	COG0339	signal peptide processing
KCU58_17120	COG2217	Heavy metal translocating P-type atpase
KCU58_17135	COG2132	Multicopper oxidase
KCU58_17150	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KCU58_17160	COG1136	(ABC) transporter
KCU58_17165	COG0577	efflux transmembrane transporter activity
KCU58_17165	COG1136	(ABC) transporter
KCU58_17170	COG0577	efflux transmembrane transporter activity
KCU58_17170	COG1136	(ABC) transporter
KCU58_17175	COG1136	(ABC) transporter
KCU58_17175	COG0577	efflux transmembrane transporter activity
KCU58_17195	COG4191	Histidine kinase
KCU58_17205	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KCU58_17220	COG0355	proton-transporting ATP synthase activity, rotational mechanism
KCU58_17235	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KCU58_17245	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KCU58_17255	COG0356	it plays a direct role in the translocation of protons across the membrane
KCU58_17270	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KCU58_17275	COG0508	dehydrogenase complex catalyzes the overall conversion of
KCU58_17310	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KCU58_17315	COG0697	spore germination
KCU58_17320	COG1666	GTP binding
KCU58_17330	COG1187	pseudouridine synthase activity
KCU58_17355	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KCU58_17355	COG2205	protein histidine kinase activity
KCU58_17380	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KCU58_17455	COG0842	Transport permease protein
KCU58_17460	COG1131	(ABC) transporter
KCU58_17465	COG0025	NhaP-type Na H and K H
KCU58_17475	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
KCU58_17480	COG1573	uracil-dna glycosylase
KCU58_17490	COG3384	dioxygenase
KCU58_17515	COG0667	Aldo Keto reductase
KCU58_17525	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KCU58_17530	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KCU58_17550	COG3706	GGDEF domain
KCU58_17555	COG2146	nitrite reductase [NAD(P)H] activity
KCU58_17560	COG5001	Diguanylate cyclase
KCU58_17590	COG4106	trans-aconitate 2-methyltransferase activity
KCU58_17600	COG2076	Multidrug Resistance protein
KCU58_17610	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KCU58_17630	COG3279	Response regulator of the LytR AlgR family
KCU58_17635	COG3275	phosphorelay sensor kinase activity
KCU58_17660	COG0531	amino acid
KCU58_17670	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
KCU58_17670	COG5297	Belongs to the glycosyl hydrolase family 6
KCU58_17685	COG0741	lytic transglycosylase activity
KCU58_17700	COG2207	Transcriptional regulator
KCU58_17710	COG0598	Magnesium transport protein CorA
KCU58_17715	COG1113	amino acid transport
KCU58_17720	COG0697	spore germination
KCU58_17730	COG0583	DNA-binding transcription factor activity
KCU58_17745	COG5520	Belongs to the glycosyl hydrolase 30 family
KCU58_17855	COG0840	transmembrane signaling receptor activity
KCU58_17870	COG2353	YceI-like domain
KCU58_17900	COG0584	glycerophosphoryl diester phosphodiesterase
KCU58_17915	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
KCU58_17935	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KCU58_17955	COG2189	Belongs to the N(4) N(6)-methyltransferase family
KCU58_17965	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KCU58_17970	COG0459	protein refolding
KCU58_17985	COG1324	tolerance protein
KCU58_17995	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KCU58_18005	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
KCU58_18010	COG0511	ligase activity, forming carbon-carbon bonds
KCU58_18015	COG0439	Biotin carboxylase
KCU58_18030	COG2264	protein methyltransferase activity
KCU58_18050	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
KCU58_18055	COG4589	Belongs to the CDS family
KCU58_18075	COG2267	carboxylic ester hydrolase activity
KCU58_18080	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KCU58_18085	COG0138	bifunctional purine biosynthesis protein purh
KCU58_18090	COG0151	Belongs to the GarS family
KCU58_18095	COG1289	transmembrane transporter activity
KCU58_18100	COG2814	Major facilitator Superfamily
KCU58_18140	COG2816	NAD+ diphosphatase activity
KCU58_18180	COG2906	2 iron, 2 sulfur cluster binding
KCU58_18210	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
KCU58_18225	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KCU58_18230	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KCU58_18235	COG0730	response to heat
KCU58_18250	COG0134	indole-3-glycerol-phosphate synthase activity
KCU58_18255	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KCU58_18275	COG1597	lipid kinase activity
KCU58_18290	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
KCU58_18305	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KCU58_18310	COG2111	Na H antiporter
KCU58_18310	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KCU58_18315	COG1006	Multisubunit Na H antiporter MnhC subunit
KCU58_18320	COG0651	ATP synthesis coupled electron transport
KCU58_18325	COG1863	multisubunit Na H antiporter MnhE subunit
KCU58_18330	COG2212	antiporter activity
KCU58_18335	COG1320	monovalent cation:proton antiporter activity
KCU58_18340	COG0530	calcium, potassium:sodium antiporter activity
KCU58_18355	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
KCU58_18375	COG3104	oligopeptide transport
KCU58_18410	COG0508	dehydrogenase complex catalyzes the overall conversion of
KCU58_18440	COG0513	Belongs to the DEAD box helicase family
KCU58_18455	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KCU58_18465	COG2354	Protein conserved in bacteria
KCU58_18490	COG3264	Mechanosensitive ion channel
KCU58_18490	COG1196	nuclear chromosome segregation
KCU58_18495	COG3321	synthase
KCU58_18495	COG1028	Short-chain dehydrogenase reductase Sdr
KCU58_18495	COG0604	alcohol dehydrogenase
KCU58_18515	COG1595	DNA-templated transcription, initiation
KCU58_18530	COG1802	Transcriptional regulator
KCU58_18565	COG3052	prosthetic group binding
KCU58_18575	COG1414	Transcriptional regulator
KCU58_18580	COG0738	Major facilitator superfamily
KCU58_18585	COG3254	rhamnose metabolic process
KCU58_18590	COG4948	Mandelate Racemase Muconate Lactonizing
KCU58_18595	COG0179	Fumarylacetoacetate (FAA) hydrolase
KCU58_18600	COG1028	Short-chain dehydrogenase reductase Sdr
KCU58_18635	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KCU58_18650	COG4807	Protein conserved in bacteria
KCU58_18675	COG4773	Receptor
KCU58_18695	COG1506	peptidase
KCU58_18695	COG0823	Involved in the tonB-independent uptake of proteins
KCU58_18755	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KCU58_18775	COG0628	permease
KCU58_18780	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KCU58_18785	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KCU58_18790	COG0753	catalase activity
KCU58_18815	COG1136	(ABC) transporter
KCU58_18820	COG0577	efflux transmembrane transporter activity
KCU58_18840	COG0697	spore germination
KCU58_18855	COG0180	Tryptophanyl-tRNA synthetase
KCU58_18890	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
KCU58_18895	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
KCU58_18895	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
KCU58_18905	COG3228	Belongs to the MtfA family
KCU58_18935	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KCU58_18960	COG2084	Dehydrogenase
KCU58_18965	COG1902	pentaerythritol trinitrate reductase activity
KCU58_18990	COG1404	Belongs to the peptidase S8 family
KCU58_18995	COG2814	Major facilitator Superfamily
KCU58_19000	COG0583	DNA-binding transcription factor activity
KCU58_19020	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KCU58_19025	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KCU58_19035	COG1764	response to oxidative stress
KCU58_19040	COG1846	Transcriptional regulator
KCU58_19045	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
KCU58_19055	COG0697	spore germination
KCU58_19060	COG0523	cobalamin synthesis protein
KCU58_19070	COG1742	UPF0060 membrane protein
KCU58_19085	COG1960	acyl-CoA dehydrogenase activity
KCU58_19090	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KCU58_19120	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KCU58_19125	COG3387	PFAM Glycoside hydrolase 15-related
KCU58_19130	COG0745	RESPONSE REGULATOR receiver
KCU58_19145	COG1404	Belongs to the peptidase S8 family
KCU58_19155	COG3100	YcgL domain-containing protein
KCU58_19160	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KCU58_19170	COG0463	Glycosyl transferase, family 2
KCU58_19205	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KCU58_19220	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KCU58_19245	COG1294	oxidase, subunit
KCU58_19250	COG1271	oxidase subunit
KCU58_19270	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KCU58_19275	COG0408	coproporphyrinogen oxidase activity
KCU58_19285	COG2323	membrane
KCU58_19290	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KCU58_19290	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KCU58_19305	COG0589	response to stress
KCU58_19325	COG0210	DNA helicase
KCU58_19375	COG0463	Glycosyl transferase, family 2
KCU58_19385	COG1475	DNA binding
KCU58_19390	COG1192	Involved in chromosome partitioning
KCU58_19395	COG0357	Ribosomal RNA small subunit methyltransferase G
KCU58_19410	COG2091	lysine biosynthetic process via aminoadipic acid
KCU58_19435	COG0477	Major facilitator Superfamily
KCU58_19455	COG1971	Probably functions as a manganese efflux pump
KCU58_19460	COG2205	protein histidine kinase activity
KCU58_19470	COG3459	Glycosyltransferase 36 associated
KCU58_19475	COG2211	Major facilitator Superfamily
KCU58_19480	COG3265	gluconokinase activity
KCU58_19495	COG2911	Protein conserved in bacteria
KCU58_19500	COG0729	surface antigen
KCU58_19520	COG3132	Protein of unknown function, DUF480
KCU58_19565	COG0284	orotidine-5'-phosphate decarboxylase activity
KCU58_19590	COG2937	Belongs to the GPAT DAPAT family
KCU58_19615	COG2211	Major facilitator Superfamily
KCU58_19630	COG3693	PFAM glycoside hydrolase, family 10
KCU58_19650	COG3386	PFAM SMP-30 Gluconolaconase
KCU58_19665	COG0246	Mannitol dehydrogenase
KCU58_19670	COG1472	Belongs to the glycosyl hydrolase 3 family
KCU58_19680	COG4948	Mandelate Racemase Muconate Lactonizing
KCU58_19690	COG3661	Belongs to the glycosyl hydrolase 67 family
KCU58_19700	COG2115	Belongs to the xylose isomerase family
KCU58_19705	COG0037	tRNA processing
KCU58_19725	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KCU58_19735	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KCU58_19745	COG0805	protein transport
KCU58_19755	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KCU58_19755	COG0519	Catalyzes the synthesis of GMP from XMP
KCU58_19760	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KCU58_19780	COG0210	DNA helicase
KCU58_19785	COG1435	thymidine kinase activity
KCU58_19795	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
KCU58_19820	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
KCU58_19835	COG1119	ATPase activity
KCU58_19855	COG0706	membrane insertase activity
KCU58_19860	COG0594	ribonuclease P activity
KCU58_19925	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KCU58_20030	COG3451	type IV secretory pathway VirB4
KCU58_20035	COG5268	conjugation
KCU58_20045	COG4962	Type ii secretion system protein e
KCU58_20050	COG4962	Type ii secretion system protein e
KCU58_20055	COG4962	Type ii secretion system protein e