locus-tag	class	description
FD63_00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
FD63_00015	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
FD63_00020	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
FD63_00025	ENOG4108TYN	CAAX amino terminal protease family protein
FD63_00030	ENOG4108K0D	peptidase, M48
FD63_00065	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
FD63_00075	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
FD63_00100	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
FD63_00105	ENOG4105CGF	Aromatic amino acid aminotransferase
FD63_00110	ENOG4105CHB	tonB-dependent Receptor
FD63_00120	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
FD63_00125	ENOG4105C26	Dehydrogenase
FD63_00155	ENOG4105DQE	DNA ligase
FD63_00160	ENOG4105DMF	Dehydrogenase
FD63_00180	ENOG4105RKW	reductase (By
FD63_00190	ENOG4105D7K	pfkb domain protein
FD63_00240	ENOG4105WPN	DNA integration recombination invertion protein
FD63_00270	ENOG4107ZSV	Receptor
FD63_00300	ENOG4105EBR	Carboxylesterase
FD63_00315	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
FD63_00325	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
FD63_00330	ENOG4105DSG	hydrolase family 43
FD63_00335	ENOG4105ETE	Transcriptional regulator (LacI family
FD63_00340	ENOG4105D50	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate (By similarity)
FD63_00345	ENOG4105CHR	reductase
FD63_00365	ENOG4105MIR	Phenylalanine 4-monooxygenase
FD63_00370	ENOG4108YXU	transcriptional regulator AsnC family
FD63_00395	ENOG4105D78	K07001 NTE family protein
FD63_00425	ENOG4105DU1	integral membrane protein, terc
FD63_00430	ENOG4105DR4	Methyltransferase
FD63_00470	ENOG4105BZW	Glycerate kinase
FD63_00475	ENOG4105NRM	Membrane
FD63_00480	ENOG4105CUB	amino acid
FD63_00485	ENOG4108ZXC	Two component transcriptional regulator, luxr family
FD63_00490	ENOG4105BZU	Histidine kinase
FD63_00510	ENOG4107QSV	RmuC domain protein
FD63_00515	ENOG4108V06	Glutathione peroxidase
FD63_00520	ENOG410903C	(LipO)protein
FD63_00535	ENOG4107PE3	Mammalian cell entry related domain protein
FD63_00540	ENOG4105CY3	ABC transporter, permease
FD63_00545	ENOG4105DHJ	ABC, transporter
FD63_00550	ENOG4105DSY	exodeoxyribonuclease V, gamma
FD63_00555	ENOG4107QKA	exodeoxyribonuclease V beta
FD63_00560	ENOG4107QYX	exodeoxyribonuclease v alpha
FD63_00580	ENOG4105K59	histidine triad (HIT) protein
FD63_00655	ENOG4105CSH	Transporter
FD63_00660	ENOG4105EUJ	GTP cyclohydrolase i
FD63_00685	ENOG4105EJ9	Membrane
FD63_00690	ENOG4105K5B	UPF0225 protein
FD63_00700	ENOG4105DSB	aldose 1-epimerase
FD63_00755	ENOG4108Z5K	methylglyoxal synthase
FD63_00775	ENOG4105BZ8	glutamate synthase
FD63_00780	ENOG4105CBC	glutamate synthase
FD63_00830	ENOG4108I5C	dEAD DEAH box helicase
FD63_00880	ENOG4105C54	Major Facilitator superfamily
FD63_00925	ENOG4107QJE	Chromosome Partitioning Protein
FD63_00930	ENOG4105M4E	phosphohistidine phosphatase, SixA
FD63_00940	ENOG4107RZC	phospholipase d
FD63_00945	ENOG4105KA0	thioesterase Superfamily protein
FD63_00955	ENOG4105E5G	Alpha beta hydrolase fold
FD63_00965	ENOG4108V1U	phospholipid-binding protein
FD63_00970	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
FD63_00975	ENOG4105C5F	glutamine synthetase
FD63_00985	ENOG4105BZU	Histidine kinase
FD63_00995	ENOG4105CUX	Signal transduction histidine kinase
FD63_01000	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FD63_01005	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
FD63_01010	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
FD63_01020	ENOG4105CHU	acetyl-coa acetyltransferase
FD63_01060	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
FD63_01065	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
FD63_01075	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
FD63_01095	ENOG4105E2T	synthase III
FD63_01100	ENOG4107R3N	Filamentation induced by cAMP protein fic
FD63_01105	ENOG4108J2P	Alpha beta hydrolase fold
FD63_01115	ENOG4105PI0	Ferredoxin
FD63_01120	ENOG410680H	amp-dependent synthetase and ligase
FD63_01130	ENOG4107S1E	Beta-lactamase
FD63_01135	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
FD63_01145	ENOG4105CPF	Cell wall formation (By similarity)
FD63_01155	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
FD63_01160	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
FD63_01165	ENOG4105DR9	pseudouridine synthase
FD63_01175	ENOG4108YZN	class I peptide chain release factor
FD63_01185	ENOG4105DGW	oligopeptidase A
FD63_01205	ENOG4105DUM	transcriptional regulator, lysR family
FD63_01210	ENOG4107QP3	malate synthase g
FD63_01220	ENOG4105BZU	Histidine kinase
FD63_01250	ENOG4105CHH	sulfate transporter
FD63_01285	ENOG4105F2Z	3-oxoadipate enol-lactonase
FD63_01290	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
FD63_01305	ENOG4108R99	pseudouridine synthase
FD63_01315	ENOG4105CQ7	ATP-dependent helicase
FD63_01320	ENOG4105F8V	Hydrolase, tatD family
FD63_01335	ENOG4105E3A	(ABC) transporter
FD63_01340	ENOG4105DA5	(ABC) transporter
FD63_01345	ENOG4108JA0	Oxidoreductase, FAD NAD(P)-binding domain protein
FD63_01355	ENOG4105VZ8	Transcriptional regulator
FD63_01365	ENOG4108IUW	ABC transporter
FD63_01380	ENOG4108TEB	UPF0114 protein
FD63_01385	ENOG4105CYM	Glutathione S-transferase
FD63_01420	ENOG4105D52	delta-aminolevulinic acid dehydratase
FD63_01440	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
FD63_01460	ENOG4105DVT	helicase
FD63_01475	ENOG4105CH6	catalase
FD63_01520	ENOG4105C8Y	Acetylornithine aminotransferase
FD63_01545	ENOG4105C02	permease
FD63_01560	ENOG4105D8V	Glucose sorbosone dehydrogenase
FD63_01595	ENOG4106032	Glutathionylspermidine synthase
FD63_01605	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
FD63_01640	ENOG4105D2S	major facilitator superfamily
FD63_01650	ENOG4108Z0R	Transferase
FD63_01665	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
FD63_01670	ENOG4105BZS	acriflavin resistance protein
FD63_01680	ENOG4105BZU	Histidine kinase
FD63_01720	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
FD63_01725	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
FD63_01730	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
FD63_01740	ENOG4105C3D	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
FD63_01745	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
FD63_01775	ENOG4105C0P	Mg chelatase subunit ChlI
FD63_01780	ENOG4105W0Z	cytoplasmic protein
FD63_01785	ENOG4108YZA	Nitrogen regulatory protein pii
FD63_01795	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
FD63_01800	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
FD63_01805	ENOG4105CEY	Amp-dependent synthetase and ligase
FD63_01815	ENOG4105EXC	Acyl-transferase
FD63_01840	ENOG4105EMU	Dehydrogenase
FD63_01850	ENOG4105C75	arginyL-tRNA synthetase
FD63_01855	ENOG4105W5Q	DNA repair protein (RadC
FD63_01860	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
FD63_01880	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
FD63_01890	ENOG4105EYM	Major Facilitator superfamily
FD63_01900	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
FD63_01905	ENOG4105DR5	peptidase
FD63_01910	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
FD63_01940	ENOG4105DQ4	alcohol dehydrogenase
FD63_01945	ENOG4107VAM	peptidase, m28
FD63_01955	ENOG41063SB	peptidase
FD63_01960	ENOG4105CN1	protease
FD63_01975	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
FD63_02005	ENOG4105C26	Dehydrogenase
FD63_02020	ENOG4105BZ9	Cytochrome C oxidase, subunit I
FD63_02030	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
FD63_02035	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
FD63_02060	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
FD63_02070	ENOG4105DHU	Bile acid
FD63_02075	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
FD63_02080	ENOG4107S2Z	UPF0761 membrane protein
FD63_02090	ENOG4105VCC	30S ribosomal protein S21
FD63_02095	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
FD63_02100	ENOG4107ZVW	dihydroneopterin aldolase
FD63_02115	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
FD63_02145	ENOG4105D5Q	Arginine ornithine antiporter
FD63_02160	ENOG4105DTQ	mandelate racemase muconate lactonizing
FD63_02170	ENOG4105D05	Receptor
FD63_02175	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
FD63_02225	ENOG4105E32	cytoplasmic protein
FD63_02240	ENOG4105BZS	acriflavin resistance protein
FD63_02245	ENOG4105BZS	acriflavin resistance protein
FD63_02250	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
FD63_02260	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
FD63_02265	ENOG4109066	lysm domain bon superfamily protein
FD63_02305	ENOG4105E9K	Isocitrate dehydrogenase
FD63_02315	ENOG4105VS7	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity)
FD63_02325	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
FD63_02330	ENOG4105K63	Thioredoxin
FD63_02335	ENOG4105C1J	atp-dependent rna helicase
FD63_02340	ENOG4105CAK	Cell division ATP-binding protein ftsE
FD63_02345	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
FD63_02350	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
FD63_02355	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
FD63_02360	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
FD63_02365	ENOG4105EN6	Membrane
FD63_02380	ENOG4105C25	Primosomal protein n'
FD63_02395	ENOG4107QI1	Mate efflux family protein
FD63_02400	ENOG4105D07	Signal peptide peptidase, SppA
FD63_02410	ENOG4105CHR	reductase
FD63_02425	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
FD63_02430	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
FD63_02445	ENOG4108RPN	Protein smg homolog
FD63_02450	ENOG4105C79	DNA protecting protein DprA
FD63_02455	ENOG4108WZM	domain protein
FD63_02460	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
FD63_02465	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
FD63_02470	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
FD63_02475	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
FD63_02490	ENOG4106WTF	Glycosyl transferase, family 2
FD63_02510	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
FD63_02515	ENOG4108Z7F	N-acetyltransferase
FD63_02525	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
FD63_02530	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
FD63_02565	ENOG4107P2S	Transcriptional regulator
FD63_02575	ENOG4105EP6	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity)
FD63_02580	ENOG4105CG3	alpha amylase, catalytic region
FD63_02595	ENOG4105MP0	transposase
FD63_02605	ENOG4105CMM	transposase
FD63_02645	ENOG4107Z3H	Transcriptional regulator, TetR family
FD63_02685	ENOG4105C8Q	Methyl-accepting chemotaxis
FD63_02700	ENOG4105WEF	catalase
FD63_02705	ENOG4108Z9Z	response to DNA damage stimulus
FD63_02710	ENOG4108N8X	transition metal ion binding
FD63_02715	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
FD63_02720	ENOG4105BZU	Histidine kinase
FD63_02725	ENOG4105EHU	Circadian clock protein KaiC
FD63_02735	ENOG4105EJ2	Transcriptional regulator
FD63_02740	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
FD63_02755	ENOG4105C7K	acetolactate synthase
FD63_02760	ENOG4105BZU	Histidine kinase
FD63_02790	ENOG4105DZR	Type I site-specific deoxyribonuclease
FD63_02805	ENOG4105F5P	DNA-damage-inducible protein d
FD63_02825	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
FD63_02830	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
FD63_02835	ENOG4105D7T	ABC transporter
FD63_02845	ENOG4108IFG	nitrite reductase, (NAD(P)H)
FD63_02850	ENOG4105KH3	nitrite reductase (NAD(P)h) small subunit
FD63_02860	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
FD63_02885	ENOG4107RTM	4-alpha-glucanotransferase (EC 2.4.1.25)
FD63_02890	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
FD63_02895	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
FD63_02900	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
FD63_02910	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
FD63_02925	ENOG4105C3A	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity)
FD63_02935	ENOG4108NEV	two component transcriptional regulator, LytTR family
FD63_02940	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
FD63_02955	ENOG4105KVH	Transcriptional regulator
FD63_02995	ENOG4105WD1	Membrane
FD63_03005	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
FD63_03015	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
FD63_03020	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
FD63_03025	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
FD63_03050	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
FD63_03055	ENOG4105CD8	aminopeptidase N
FD63_03060	ENOG4107TTQ	Alpha beta hydrolase fold
FD63_03085	ENOG4105DFF	Rod shape-determining protein mreb
FD63_03090	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
FD63_03100	ENOG4105CJN	penicillin-binding protein
FD63_03105	ENOG4105CNI	cell division protein FtsW
FD63_03125	ENOG4105CVE	Lytic murein transglycosylase
FD63_03135	ENOG4105DZ1	carboxypeptidase
FD63_03170	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
FD63_03175	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
FD63_03180	ENOG4105CN1	protease
FD63_03235	ENOG4105CSA	Coproporphyrinogen iii oxidase
FD63_03240	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
FD63_03245	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
FD63_03250	ENOG4105DSJ	YicC domain protein
FD63_03255	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
FD63_03260	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
FD63_03265	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
FD63_03275	ENOG4105KME	endoribonuclease L-psp
FD63_03280	ENOG4105CB5	ATP-dependent DNA helicase recG
FD63_03285	ENOG4105DU0	nucleoside hydrolase
FD63_03290	ENOG4105NRA	50s ribosomal protein l31 type b
FD63_03295	ENOG4105BZN	citrate synthase
FD63_03310	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
FD63_03330	ENOG4105D9N	nucleoside
FD63_03335	ENOG4105CPC	Aldo Keto reductase
FD63_03345	ENOG4105D05	Receptor
FD63_03365	ENOG4105CV6	ABC transporter, permease
FD63_03370	ENOG4108I0Y	(ABC) transporter
FD63_03375	ENOG4108UJV	acyl-CoA thioesterase i
FD63_03380	ENOG4105ETX	regulatoR
FD63_03385	ENOG4105DHQ	Histidine kinase
FD63_03395	ENOG41080IJ	Diacylglycerol kinase
FD63_03400	ENOG4105EE5	Membrane protein terC
FD63_03405	ENOG4108V0P	LemA family
FD63_03420	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
FD63_03425	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
FD63_03435	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
FD63_03440	ENOG4105NWN	ApaG protein
FD63_03445	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
FD63_03455	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
FD63_03460	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
FD63_03465	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
FD63_03470	ENOG4105DGU	Histone deacetylase
FD63_03475	ENOG4108WBT	adenosyltransferase
FD63_03485	ENOG4105D0A	hydroxylase
FD63_03490	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
FD63_03510	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
FD63_03530	ENOG4105DXC	membrane
FD63_03535	ENOG4105CX6	glutaminyL-tRNA synthetase
FD63_03555	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
FD63_03560	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
FD63_03565	ENOG4105NXH	GreA GreB family elongation factor
FD63_03575	ENOG4105C5Q	Transcriptional regulator
FD63_03600	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
FD63_03605	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
FD63_03610	ENOG4105C5H	ABC transporter
FD63_03620	ENOG4105ETT	transcriptional Regulator, LysR family
FD63_03635	ENOG4105HSS	phospholipase C
FD63_03660	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
FD63_03670	ENOG4105DJQ	tetratricopeptide tpr_2 repeat protein
FD63_03680	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
FD63_03690	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
FD63_03700	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
FD63_03705	ENOG4105C3G	gtp-binding protein
FD63_03725	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
FD63_03735	ENOG4105PM1	preprotein translocase subunit SecE
FD63_03740	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
FD63_03745	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
FD63_03750	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
FD63_03755	ENOG4108VZM	50s ribosomal protein L10
FD63_03760	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
FD63_03770	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
FD63_03775	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
FD63_03780	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
FD63_03785	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
FD63_03790	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
FD63_03795	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
FD63_03800	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
FD63_03805	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
FD63_03810	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
FD63_03815	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FD63_03820	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
FD63_03825	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
FD63_03835	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
FD63_03845	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
FD63_03850	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
FD63_03855	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
FD63_03860	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FD63_03865	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
FD63_03875	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
FD63_03880	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
FD63_03885	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
FD63_03890	ENOG41087MT	50S ribosomal protein L30
FD63_03895	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
FD63_03900	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
FD63_03905	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FD63_03910	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
FD63_03915	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
FD63_03920	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
FD63_03925	ENOG4108ZT0	50S ribosomal protein l17
FD63_03930	ENOG41080I0	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
FD63_03940	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
FD63_03955	ENOG4105CI3	gtp-binding protein typa
FD63_03960	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
FD63_03970	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
FD63_03985	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
FD63_03990	ENOG4108K3A	Glutathione S-transferase
FD63_04035	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
FD63_04045	ENOG4105CPC	Aldo Keto reductase
FD63_04070	ENOG4105F37	PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6
FD63_04085	ENOG4108R99	pseudouridine synthase
FD63_04090	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
FD63_04095	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
FD63_04100	ENOG4108I5D	sulfate abc transporter
FD63_04110	ENOG4108IJ6	ABC transporter
FD63_04120	ENOG4105CPQ	Dehydrogenase
FD63_04130	ENOG4107RPC	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
FD63_04135	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
FD63_04150	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
FD63_04155	ENOG4105ED9	Protein of unknown function (DUF455)
FD63_04160	ENOG4108YP4	Metalloprotease, specifically cleaves on the N-terminal side of aspartyl, glutamyl and cysteic acid residues (By similarity)
FD63_04170	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
FD63_04180	ENOG4105BZF	Glycosyl transferase (Group 1
FD63_04185	ENOG4105C9X	ppx gppa phosphatase
FD63_04190	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
FD63_04195	ENOG4105BZU	Histidine kinase
FD63_04200	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
FD63_04205	ENOG4105ERG	peptidase m48, ste24p
FD63_04210	ENOG4105VW4	glutaredoxin 3
FD63_04220	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
FD63_04260	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
FD63_04265	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
FD63_04270	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
FD63_04300	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
FD63_04310	ENOG41068JE	domain protein
FD63_04315	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
FD63_04325	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
FD63_04330	ENOG4107RZZ	dna polymerase iii epsilon subunit
FD63_04335	ENOG4108ZF3	Phosphatase
FD63_04355	ENOG4105DKP	glycosyl transferase, family 9
FD63_04360	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
FD63_04365	ENOG4107UV6	ribonuclease Z
FD63_04370	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
FD63_04385	ENOG4105M00	molybdopterin converting factor, subunit 1
FD63_04390	ENOG4108ZAF	Molybdopterin
FD63_04405	ENOG4107QMP	dna polymerase iii subunits gamma and tau
FD63_04410	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
FD63_04420	ENOG4105K59	histidine triad (HIT) protein
FD63_04430	ENOG4105F8C	transglutaminase domain-containing protein
FD63_04440	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
FD63_04465	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
FD63_04470	ENOG4105VGS	50s ribosomal protein l32
FD63_04475	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
FD63_04480	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
FD63_04485	ENOG4105CHR	reductase
FD63_04495	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
FD63_04500	ENOG4105CRQ	synthase (Component I)
FD63_04505	ENOG4105HHA	aminodeoxychorismate lyase
FD63_04510	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
FD63_04515	ENOG4107QRG	dna polymerase iii
FD63_04530	ENOG4105KRQ	Addiction module toxin, Txe YoeB family
FD63_04535	ENOG4105VTW	prevent-host-death family
FD63_04570	ENOG4105C0B	DNA polymerase III (alpha subunit)
FD63_04585	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
FD63_04590	ENOG4105BZN	citrate synthase
FD63_04595	ENOG4105CR4	methylisocitrate lyase
FD63_04600	ENOG4105BZN	citrate synthase
FD63_04605	ENOG4108I0Z	Aconitate hydratase
FD63_04615	ENOG4105C7F	AcnD-accessory protein PrpF
FD63_04630	ENOG4105DN3	alpha-2-macroglobulin domain protein
FD63_04650	ENOG4108JQB	penicillin-binding protein 1C
FD63_04675	ENOG4105M3Z	response regulator
FD63_04685	ENOG4107QJR	hflk protein
FD63_04690	ENOG4105EPW	hflc protein
FD63_04725	ENOG4105CVR	type I restriction-modification system
FD63_04750	ENOG4105CMM	transposase
FD63_04815	ENOG4105E2A	Dehydrogenase
FD63_04825	ENOG4108TN2	lmbE family
FD63_04830	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
FD63_04850	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FD63_04870	ENOG4108JJA	ABC, transporter
FD63_04875	ENOG4105C2C	drug resistance transporter, Bcr CflA
FD63_04895	ENOG4105DIJ	Phosphoethanolamine transferase
FD63_04905	ENOG4105ETX	regulatoR
FD63_04910	ENOG4105C08	Histidine kinase
FD63_04925	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
FD63_04930	ENOG4107QMS	site-determining protein
FD63_04935	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
FD63_04945	ENOG4105BZU	Histidine kinase
FD63_04975	ENOG4105K64	Glycosyl transferase, family 2
FD63_04980	ENOG4105BZ4	penicillin-binding protein
FD63_04990	ENOG4105DVT	helicase
FD63_04995	ENOG41072GX	Peptidase M22 Glycoprotease
FD63_05025	ENOG4105D7Z	glutathione synthase
FD63_05030	ENOG4108UNF	response regulator
FD63_05035	ENOG4105M3Z	response regulator
FD63_05040	ENOG410807Z	Modulation of CheA activity in response to attractants (Chemotaxis
FD63_05045	ENOG4105C8Q	Methyl-accepting chemotaxis
FD63_05050	ENOG4105CBS	Chea signal transduction histidine kinase
FD63_05055	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
FD63_05075	ENOG4105CMM	transposase
FD63_05085	ENOG4106N3A	copper homeostasis protein cutc
FD63_05105	ENOG4105C9M	aspartyl-trna synthetase
FD63_05125	ENOG4105CDY	transcriptional regulatory protein
FD63_05130	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
FD63_05135	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
FD63_05140	ENOG4105DFH	Transport of potassium into the cell (By similarity)
FD63_05150	ENOG4107YD3	Thioesterase
FD63_05155	ENOG4105E02	MotA TolQ exbB proton channel
FD63_05160	ENOG4105M8F	Biopolymer transport protein exbD tolR
FD63_05170	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
FD63_05175	ENOG4105KCK	Peptidoglycan-associated lipoprotein
FD63_05185	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
FD63_05215	ENOG4105C9U	ATP-dependent DNA helicase RecQ
FD63_05230	ENOG4105CQ7	ATP-dependent helicase
FD63_05245	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
FD63_05260	ENOG4105JIE	May be involved in the transport of PQQ or its precursor to the periplasm (By similarity)
FD63_05270	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
FD63_05320	ENOG4108EF9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
FD63_05330	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
FD63_05345	ENOG4105C29	acyl-CoA thioesterase
FD63_05360	ENOG4108TGP	Thioesterase superfamily protein
FD63_05365	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
FD63_05370	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
FD63_05380	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FD63_05385	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
FD63_05390	ENOG4105CJR	Integral membrane protein (MviN
FD63_05405	ENOG4105DTN	riboflavin biosynthesis protein ribF
FD63_05410	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
FD63_05415	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
FD63_05420	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
FD63_05435	ENOG4105E2S	oxidase) subunit II
FD63_05440	ENOG4105BZ9	Cytochrome C oxidase, subunit I
FD63_05445	ENOG4105CCU	oxidase (Subunit III)
FD63_05450	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
FD63_05460	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
FD63_05465	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
FD63_05470	ENOG4105KAF	membrAne
FD63_05495	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
FD63_05545	ENOG4108HR8	type iii secretion
FD63_05565	ENOG4107Y59	type iii secretion
FD63_05580	ENOG4108JIR	Flagellum-specific ATP synthase
FD63_05600	ENOG4105K44	type iii secretion
FD63_05615	ENOG4105FTC	Lytic transglycosylase catalytic
FD63_05620	ENOG4105C01	Dihydroxy-acid dehydratase
FD63_05640	ENOG4105C26	Dehydrogenase
FD63_05645	ENOG4107R5U	Periplasmic binding protein LacI transcriptional regulator
FD63_05650	ENOG4105C2J	ABC transporter
FD63_05655	ENOG4107R9N	ABC transporter
FD63_05660	ENOG41062B0	ABC transporter, permease
FD63_05670	ENOG4105CGS	Alpha-glucosidase
FD63_05675	ENOG4108TGY	Glutathione S-transferase
FD63_05695	ENOG4105CZZ	Alpha-N-arabinofuranosidase (EC 3.2.1.55)
FD63_05700	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
FD63_05710	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FD63_05715	ENOG4105EA8	2-Nitropropane dioxygenase
FD63_05725	ENOG4105K5M	30s ribosomal protein S16
FD63_05730	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
FD63_05735	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
FD63_05740	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
FD63_05745	ENOG4107QJQ	Mate efflux family protein
FD63_05755	ENOG4105VEJ	Heat shock protein
FD63_05760	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
FD63_05775	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
FD63_05790	ENOG4105HMI	Membrane
FD63_05815	ENOG4105EMN	RNA polymerase sigma factor
FD63_05825	ENOG4105C0H	protease
FD63_05835	ENOG4105C3F	Signal peptidase i
FD63_05845	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
FD63_05850	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
FD63_05860	ENOG4105EFQ	Two component transcriptional regulator (Winged helix family
FD63_05870	ENOG41080ZE	Adenylate cyclase
FD63_05880	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
FD63_05885	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
FD63_05890	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
FD63_05895	ENOG4105VEQ	Cold shock protein
FD63_05900	ENOG41061H0	Monooxygenase
FD63_05910	ENOG4107QRT	dEAD DEAH box helicase
FD63_05915	ENOG4107T0X	DNA ligase
FD63_05920	ENOG4107T0X	DNA ligase
FD63_05940	ENOG4105BZU	Histidine kinase
FD63_05955	ENOG4105F7F	Chaperone
FD63_05965	ENOG4105CHU	acetyl-coa acetyltransferase
FD63_05995	ENOG4105D5P	Methylmalonyl-coA mutase
FD63_06030	ENOG4108MHS	Lysyl endopeptidase
FD63_06055	ENOG4105CNT	hydrolase family 2
FD63_06060	ENOG4107EJG	GntR family transcriptional regulator
FD63_06070	ENOG4105BZU	Histidine kinase
FD63_06095	ENOG4108VKG	metal-dependent hydrolase
FD63_06110	ENOG4105KSC	Transcriptional regulator, TraR DksA family
FD63_06140	ENOG4108MIC	Mg-protoporphyrin IX methyl transferase
FD63_06150	ENOG4108YZY	peptidylprolyl cis-trans isomerase
FD63_06155	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
FD63_06160	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
FD63_06170	ENOG4105F27	Major Facilitator
FD63_06210	ENOG4105M4H	endoribonuclease L-psp
FD63_06230	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
FD63_06255	ENOG4105K6V	RNA polymerase
FD63_06290	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
FD63_06300	ENOG4108IQI	permease
FD63_06305	ENOG4107QK5	Homocysteine s-methyltransferase
FD63_06330	ENOG4105K63	Thioredoxin
FD63_06340	ENOG4105C8T	Leucyl-tRNA synthetase
FD63_06355	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
FD63_06385	ENOG4105MPN	Membrane
FD63_06390	ENOG4108Z03	MAF-like protein
FD63_06395	ENOG4105C03	ribonuclease
FD63_06405	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
FD63_06410	ENOG4105N42	UPF0307 protein
FD63_06415	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
FD63_06440	ENOG4108WC9	type VI secretion system effector, hcp1 family
FD63_06465	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
FD63_06490	ENOG4105CS6	Rhs element vgr protein
FD63_06525	ENOG4108ZF3	Phosphatase
FD63_06530	ENOG4105D9P	serine threonine protein kinase
FD63_06555	ENOG4105CA0	peroxidase
FD63_06565	ENOG4105CTB	Polyprenyl synthetase
FD63_06570	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
FD63_06575	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
FD63_06585	ENOG4105G6Z	alkaline phosphatase
FD63_06590	ENOG4105CK2	sodium dicarboxylate symporter
FD63_06615	ENOG4105K4H	Nlp p60 protein
FD63_06620	ENOG4105K4H	Nlp p60 protein
FD63_06625	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
FD63_06635	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
FD63_06645	ENOG41075CH	type III effector
FD63_06650	ENOG41075CH	type III effector
FD63_06690	ENOG4105C9K	Endothelin-converting enzyme 1
FD63_06705	ENOG4107RDJ	Sulfotransferase
FD63_06715	ENOG4105D05	Receptor
FD63_06720	ENOG4105CMM	transposase
FD63_06730	ENOG4105D05	Receptor
FD63_06745	ENOG4105DHP	deoxycytidine triphosphate deaminase
FD63_06750	ENOG4105HHM	rdd domain containing protein
FD63_06770	ENOG4108RRZ	Transcription elongation factor GreB
FD63_06785	ENOG4107VIJ	nudix hydrolase
FD63_06790	ENOG4105D7A	ATP-binding protein
FD63_06795	ENOG4106770	Is able to cleave peptidoglycan (By similarity)
FD63_06800	ENOG4105DJ4	phosphatidylserine decarboxylase
FD63_06810	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
FD63_06815	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
FD63_06825	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
FD63_06835	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
FD63_06840	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
FD63_06855	ENOG4108MGI	Transcriptional regulator
FD63_06860	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
FD63_06875	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
FD63_06880	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
FD63_06900	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
FD63_06905	ENOG4105CP7	Triose-phosphate isomerase
FD63_06920	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FD63_06925	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
FD63_06930	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FD63_06940	ENOG4105GKE	subunit e
FD63_06945	ENOG4107QIZ	NADH dehydrogenase
FD63_06950	ENOG4108IEH	NADH dehydrogenase subunit g
FD63_06955	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
FD63_06960	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
FD63_06965	ENOG4105DF2	NADH dehydrogenase subunit j
FD63_06970	ENOG41080FQ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
FD63_06975	ENOG4105D65	subunit l
FD63_06980	ENOG4105C8S	subunit m
FD63_06985	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
FD63_07000	ENOG4105CHV	Transcription elongation factor NusA
FD63_07005	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
FD63_07020	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
FD63_07025	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
FD63_07030	ENOG4105BZU	Histidine kinase
FD63_07055	ENOG4105C8Q	Methyl-accepting chemotaxis
FD63_07060	ENOG4105C8Q	Methyl-accepting chemotaxis
FD63_07065	ENOG4108V3W	Chemotaxis protein, CheW
FD63_07105	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
FD63_07110	ENOG4105CEN	a g-specific adenine glycosylase
FD63_07115	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
FD63_07125	ENOG4105CTU	Proline racemase
FD63_07130	ENOG41080HI	glycine oxidase
FD63_07145	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
FD63_07155	ENOG4105DC7	peptidase M24
FD63_07170	ENOG4107QTZ	amino acid
FD63_07195	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
FD63_07205	ENOG4107PMW	Arabinan endo-1,5-alpha-L-arabinosidase
FD63_07215	ENOG4105D05	Receptor
FD63_07230	ENOG4105DG4	malate L-lactate dehydrogenase
FD63_07235	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
FD63_07240	ENOG4106H78	methyltransferase
FD63_07255	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
FD63_07260	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
FD63_07265	ENOG4105C8F	Beta-lactamase domain protein
FD63_07270	ENOG4105E08	Glycoside hydrolase, family 9
FD63_07275	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
FD63_07285	ENOG4105C8Y	Acetylornithine aminotransferase
FD63_07295	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
FD63_07305	ENOG4105VIE	preprotein translocase, subunit YajC
FD63_07310	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
FD63_07315	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
FD63_07340	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
FD63_07355	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
FD63_07360	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
FD63_07365	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
FD63_07395	ENOG4105CD3	dihydroorotase
FD63_07405	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FD63_07465	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
FD63_07470	ENOG4105C8N	cysteinyl-tRNA synthetase
FD63_07480	ENOG4105DBV	ornithine carbamoyltransferase
FD63_07485	ENOG4105CDH	Citrulline--aspartate ligase
FD63_07495	ENOG4105CAS	nag kinase
FD63_07505	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
FD63_07510	ENOG4105CH7	arginosuccinase
FD63_07525	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
FD63_07530	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
FD63_07555	ENOG4105CMG	Carbohydrate kinase
FD63_07560	ENOG4105C93	Xylose Isomerase
FD63_07570	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
FD63_07590	ENOG4105DJ0	Poly(A) Polymerase
FD63_07600	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
FD63_07605	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
FD63_07615	ENOG4107QP8	phosphohexose isomerase
FD63_07645	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
FD63_07655	ENOG4105BZU	Histidine kinase
FD63_07670	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
FD63_07675	ENOG410841Q	phosphoesterase PA-phosphatase related protein
FD63_07695	ENOG4105D4A	Cell wall formation (By similarity)
FD63_07700	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
FD63_07715	ENOG4105C26	Dehydrogenase
FD63_07735	ENOG4105CFH	Aspartokinase
FD63_07740	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
FD63_07745	ENOG4105CVE	Lytic murein transglycosylase
FD63_07755	ENOG4105D98	threonine synthase
FD63_07765	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
FD63_07780	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
FD63_07785	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
FD63_07790	ENOG4105CIH	Imidazole acetol-phosphate transaminase
FD63_07800	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
FD63_07805	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
FD63_07810	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
FD63_07815	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
FD63_07835	ENOG4106YVY	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) (By similarity)
FD63_07840	ENOG4108CAF	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity)
FD63_07845	ENOG4107QY0	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity)
FD63_07850	ENOG4105CUB	amino acid
FD63_07855	ENOG4105CUB	amino acid
FD63_07870	ENOG4108JQ1	Dehydrogenase
FD63_07875	ENOG4105CQB	FAD linked oxidase domain protein
FD63_07895	ENOG4105FUQ	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
FD63_07905	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
FD63_07915	ENOG4105E39	Enoyl-CoA hydratase
FD63_07925	ENOG4105CE1	Ferrous iron transport protein b
FD63_07945	ENOG4105C22	threonyL-tRNA synthetase
FD63_07950	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
FD63_07955	ENOG41082NX	50s ribosomal protein l35
FD63_07960	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
FD63_07965	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
FD63_07970	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
FD63_07975	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
FD63_07980	ENOG4105WJX	transcriptional regulator MERR family
FD63_08000	ENOG4105D3Q	Sugar transferase
FD63_08020	ENOG4107Y2G	Glycosyl transferase (Group 1
FD63_08030	ENOG4108NQK	Catalyzes the transfer of a glucuronic acid (GlcA) residue from UDP-glucuronate to mannose-alpha-1,3-glucose-beta- 1,4-glucose-P-P-polyisoprenyl to form the lipid-linked tetrasaccharide GlcA-Man-Glc(2)-PP-Pol, with a glucuronic acid- beta-mannose linkage. Is involved in the biosynthesis of the exopolysaccharide xanthan, since it catalyzes the fourth glycosylation step in the assembly of the pentasaccharide-P-P- polyisoprenyl repeating unit of xanthan. Is unable to use the trisaccharide acceptor freed from the pyrophosphate lipid moiety. Does not show specificity for the lipidic portion of the acceptor. Shows diminished activity when tested with 6-O-acetyl-mannose- alpha-1,3-glucose-beta-1,4-glucose-P-P-polyisoprenyl, a
FD63_08050	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
FD63_08060	ENOG4105CSU	acyl-Coa dehydrogenase
FD63_08065	ENOG4105Y49	secretion protein, HlyD family
FD63_08115	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
FD63_08125	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
FD63_08130	ENOG4105K8N	protein family UPF0079, ATPase
FD63_08135	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
FD63_08140	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
FD63_08160	ENOG4105CHR	reductase
FD63_08165	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
FD63_08170	ENOG4105D0M	Protease HtpX homolog
FD63_08180	ENOG4105CBX	hi0933 family
FD63_08185	ENOG4108VWS	Yaeq family
FD63_08195	ENOG4105VEQ	Cold shock protein
FD63_08200	ENOG4108K3A	Glutathione S-transferase
FD63_08210	ENOG4105CNG	UPF0061 protein
FD63_08220	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
FD63_08230	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
FD63_08235	ENOG4105C1J	atp-dependent rna helicase
FD63_08240	ENOG4105C5H	ABC transporter
FD63_08255	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
FD63_08265	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
FD63_08275	ENOG4105DUX	Transporter
FD63_08305	ENOG41090MY	MarR family Transcriptional regulator
FD63_08320	ENOG4105DP0	ferredoxin-NADP reductase
FD63_08340	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
FD63_08350	ENOG4107GFK	fumarate
FD63_08365	ENOG4105HDD	phospholipase
FD63_08375	ENOG4105VEQ	Cold shock protein
FD63_08390	ENOG4105CUZ	uba thif-type nad fad binding protein
FD63_08395	ENOG4105F8V	Hydrolase, tatD family
FD63_08410	ENOG4105C1G	acyl-Coa dehydrogenase
FD63_08425	ENOG4105CDU	Replicative dna helicase
FD63_08430	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
FD63_08440	ENOG4105CDV	Ompa motb domain protein
FD63_08445	ENOG4105EJC	lysr family transcriptional regulator
FD63_08460	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
FD63_08495	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
FD63_08500	ENOG4108Z1B	Cyclase dehydrase
FD63_08510	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
FD63_08515	ENOG41090R7	Ferric uptake
FD63_08520	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
FD63_08525	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
FD63_08530	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FD63_08535	ENOG4105CFG	Acts as a chaperone (By similarity)
FD63_08540	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
FD63_08550	ENOG4105EHE	chorismate mutase- prephenate dehydrogenase
FD63_08560	ENOG4105BZ1	(ABC) transporter
FD63_08580	ENOG4105BZU	Histidine kinase
FD63_08585	ENOG4108URH	decarboxylase
FD63_08595	ENOG4105C7S	Dehydrogenase
FD63_08600	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
FD63_08610	ENOG4105EZE	Cupin 4 family protein
FD63_08625	ENOG4107QTF	adenylosuccinate lyase
FD63_08660	ENOG4105CZV	ABC transporter
FD63_08665	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
FD63_08675	ENOG4108V06	Glutathione peroxidase
FD63_08680	ENOG4108V1T	peptidylprolyl cis-trans isomerase
FD63_08685	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
FD63_08690	ENOG41069P5	Protein slyX homolog
FD63_08700	ENOG4105EXC	Acyl-transferase
FD63_08710	ENOG4105C3R	Methionine synthase
FD63_08715	ENOG4105C3R	Methionine synthase
FD63_08725	ENOG4105C1G	acyl-Coa dehydrogenase
FD63_08810	ENOG4108781	Fimbrial protein
FD63_08815	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
FD63_08830	ENOG4105BZS	acriflavin resistance protein
FD63_08835	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
FD63_08845	ENOG4105C7I	Dehydrogenase
FD63_08880	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
FD63_08885	ENOG4105C4M	(Ubiquinol oxidase) subunit I
FD63_08890	ENOG4108JJ9	ABC, transporter
FD63_08895	ENOG4108JJ8	(ABC) transporter
FD63_08900	ENOG4105DWV	Homoserine O-trans-acetylase
FD63_08910	ENOG4105KWW	Biogenesis protein
FD63_08920	ENOG4105DA4	cytochrome c-type biogenesis protein
FD63_08925	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
FD63_08935	ENOG41060IM	Heme exporter protein
FD63_08940	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
FD63_08945	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
FD63_08950	ENOG4105CHM	Aminotransferase
FD63_08975	ENOG4105FE9	pseudouridine synthase
FD63_08980	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
FD63_08985	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
FD63_08990	ENOG4105K9H	YciI-like protein
FD63_09025	ENOG4105DRS	transport system, permease
FD63_09035	ENOG4108UHU	Aldolase
FD63_09040	ENOG4105C01	Dihydroxy-acid dehydratase
FD63_09065	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
FD63_09070	ENOG410612Q	succinate dehydrogenase (cytochrome b-556 subunit)
FD63_09085	ENOG4105E33	succinate dehydrogenase
FD63_09090	ENOG410681N	tpr repeat protein
FD63_09100	ENOG4105D60	lipoprotein releasing system transmembrane protein
FD63_09115	ENOG4108EC8	DNA internalization-related competence protein ComEC
FD63_09130	ENOG4105BZ1	(ABC) transporter
FD63_09155	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
FD63_09160	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
FD63_09200	ENOG4105JAS	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene) (By similarity)
FD63_09205	ENOG4108JPW	Aminotransferase
FD63_09215	ENOG4105J3Q	acyl carrier protein
FD63_09245	ENOG4105CMM	transposase
FD63_09275	ENOG4105BZ1	(ABC) transporter
FD63_09295	ENOG4105WH1	Two component transcriptional regulator luxr family
FD63_09305	ENOG4105C03	ribonuclease
FD63_09310	ENOG4105EI2	Pseudouridine synthase
FD63_09320	ENOG4105DUN	Mediates zinc uptake. May also transport other divalent cations (By similarity)
FD63_09335	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
FD63_09350	ENOG4106RE7	Cytochrome
FD63_09355	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
FD63_09380	ENOG4105DWY	Agmatine deiminase
FD63_09390	ENOG4105YK5	50S ribosomal protein L36
FD63_09395	ENOG4105CAT	Cytidine monophosphate kinase
FD63_09400	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
FD63_09405	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
FD63_09415	ENOG4105CFV	Tetratricopeptide repeat protein
FD63_09420	ENOG4105ESV	Glycosyl transferase, family 4
FD63_09430	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
FD63_09435	ENOG4105CHU	acetyl-coa acetyltransferase
FD63_09450	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
FD63_09465	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
FD63_09475	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
FD63_09480	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
FD63_09485	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
FD63_09490	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
FD63_09495	ENOG4105D06	uba thif-type nad fad binding protein
FD63_09500	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
FD63_09515	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
FD63_09520	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
FD63_09525	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
FD63_09545	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
FD63_09550	ENOG4105KST	dependent repressor
FD63_09555	ENOG4108Z6B	deaminase
FD63_09560	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
FD63_09575	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
FD63_09595	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
FD63_09605	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
FD63_09625	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
FD63_09635	ENOG4105CQZ	Histidine kinase
FD63_09640	ENOG4105BZM	domain protein
FD63_09645	ENOG4105BZU	Histidine kinase
FD63_09710	ENOG4105F32	YngK protein
FD63_09715	ENOG4105MP0	transposase
FD63_09730	ENOG4105DMF	Dehydrogenase
FD63_09815	ENOG4105IBP	Cyclic peptide transporter
FD63_09865	ENOG4107QKA	exodeoxyribonuclease V beta
FD63_09895	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
FD63_09905	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
FD63_09910	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
FD63_09920	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
FD63_09925	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
FD63_09930	ENOG4108RPX	mosc domain containing protein
FD63_09935	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
FD63_09955	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
FD63_09960	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
FD63_09980	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
FD63_10000	ENOG4105EGZ	biosynthesis protein
FD63_10030	ENOG4108VKM	cytochrome b561
FD63_10050	ENOG4105EMN	RNA polymerase sigma factor
FD63_10065	ENOG41060IM	Heme exporter protein
FD63_10080	ENOG4105DA4	cytochrome c-type biogenesis protein
FD63_10085	ENOG4107QX9	Thiol disulfide interChange protein
FD63_10090	ENOG4105KWW	Biogenesis protein
FD63_10105	ENOG4107R4J	Chloride channel
FD63_10110	ENOG4105D1H	recombination factor protein RarA
FD63_10120	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
FD63_10130	ENOG4105CNU	cell division protein FtsK
FD63_10135	ENOG4105C3M	thioredoxin reductase
FD63_10145	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
FD63_10150	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
FD63_10155	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
FD63_10160	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
FD63_10175	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
FD63_10205	ENOG4105BZU	Histidine kinase
FD63_10215	ENOG4105BZU	Histidine kinase
FD63_10240	ENOG4107R88	Chemotaxis protein (CheV)
FD63_10250	ENOG4108ZC9	flagellar basal-body rod protein flgc
FD63_10255	ENOG4105W00	Flagellar hook capping protein
FD63_10260	ENOG4105BZE	flagellar hook protein, FlgE
FD63_10265	ENOG4108KPB	Flagellar basal-body rod protein FlgF
FD63_10270	ENOG4105CGA	flagellar basal-body rod protein FlgG
FD63_10275	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
FD63_10285	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
FD63_10290	ENOG4105E1Q	flagellar hook-associated protein
FD63_10290	ENOG4105E1Q	flagellar hook-associated protein
FD63_10295	ENOG4105DTJ	flagellar hook-associated protein
FD63_10305	ENOG4107W9T	flagellar hook-associated
FD63_10310	ENOG4105MQ3	flagellar protein FliS
FD63_10325	ENOG4105WH1	Two component transcriptional regulator luxr family
FD63_10330	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
FD63_10335	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
FD63_10340	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FD63_10355	ENOG4108P1X	synthase
FD63_10365	ENOG4105CHR	reductase
FD63_10390	ENOG4107RGC	Glycosyl transferase, family 2
FD63_10395	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
FD63_10400	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
FD63_10405	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
FD63_10415	ENOG4108JIR	Flagellum-specific ATP synthase
FD63_10435	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
FD63_10440	ENOG4105DD5	Flagellar motor switch protein
FD63_10445	ENOG4105K0P	flagellar biosynthesis protein
FD63_10450	ENOG4105CN7	Flagellar biosynthetic protein FliP
FD63_10455	ENOG4105VS8	Flagellar biosynthetic protein fliq
FD63_10460	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
FD63_10465	ENOG4105BZU	Histidine kinase
FD63_10470	ENOG4105BZU	Histidine kinase
FD63_10475	ENOG4105D00	flagellar biosynthetic protein flhB
FD63_10480	ENOG4105D7B	Flagellar biosynthesis protein flha
FD63_10485	ENOG4105FZW	flagellar biosynthesis regulator FlhF
FD63_10490	ENOG4107R21	site-determining protein
FD63_10495	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
FD63_10500	ENOG4108VYJ	response regulator receiver protein
FD63_10505	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
FD63_10510	ENOG4105CBS	Chea signal transduction histidine kinase
FD63_10515	ENOG4105E14	MotA TolQ exbB proton channel
FD63_10520	ENOG4106VK6	Flagellar motor protein
FD63_10525	ENOG4107QJE	Chromosome Partitioning Protein
FD63_10530	ENOG4108V3W	Chemotaxis protein, CheW
FD63_10540	ENOG4108VYJ	response regulator receiver protein
FD63_10545	ENOG4105CBS	Chea signal transduction histidine kinase
FD63_10555	ENOG4105C8Q	Methyl-accepting chemotaxis
FD63_10560	ENOG4105C8Q	Methyl-accepting chemotaxis
FD63_10565	ENOG4105C8Q	Methyl-accepting chemotaxis
FD63_10580	ENOG4105C8Q	Methyl-accepting chemotaxis
FD63_10590	ENOG4105C8Q	Methyl-accepting chemotaxis
FD63_10595	ENOG4105C8Q	Methyl-accepting chemotaxis
FD63_10600	ENOG4105C8Q	Methyl-accepting chemotaxis
FD63_10610	ENOG4105C8Q	Methyl-accepting chemotaxis
FD63_10620	ENOG4108V3W	Chemotaxis protein, CheW
FD63_10630	ENOG4105C8Q	Methyl-accepting chemotaxis
FD63_10640	ENOG4105C8Q	Methyl-accepting chemotaxis
FD63_10645	ENOG4105BZU	Histidine kinase
FD63_10650	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
FD63_10655	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
FD63_10660	ENOG4105BZU	Histidine kinase
FD63_10680	ENOG4107QIJ	Aconitate hydratase 2
FD63_10695	ENOG4107QM5	aconitate hydratase
FD63_10705	ENOG4105CEY	Amp-dependent synthetase and ligase
FD63_10715	ENOG4105BZU	Histidine kinase
FD63_10720	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
FD63_10730	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
FD63_10750	ENOG4108RTU	Aldolase
FD63_10755	ENOG4105CXK	mandelate racemase muconate lactonizing
FD63_10765	ENOG4105EI3	2-dehydro-3-deoxygalactonokinase EC 2.7.1.58
FD63_10770	ENOG4108Z4U	Ferredoxin
FD63_10780	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
FD63_10790	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FD63_10795	ENOG4108IAB	Phoh family
FD63_10830	ENOG4105DWF	phosphomethylpyrimidine kinase
FD63_10855	ENOG4105F52	Transcriptional regulator
FD63_10885	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
FD63_10900	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
FD63_10905	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
FD63_10910	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
FD63_10915	ENOG4107TH8	cina domain protein
FD63_10920	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
FD63_10925	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
FD63_10930	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
FD63_10935	ENOG4105EEI	dihydropteroate synthase
FD63_10940	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
FD63_10945	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
FD63_10950	ENOG4105HBR	Rna-binding protein
FD63_10960	ENOG4108K5P	(LipO)protein
FD63_10965	ENOG4108UM1	dedA family
FD63_10970	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
FD63_10975	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
FD63_10985	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
FD63_10990	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
FD63_11000	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
FD63_11005	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
FD63_11010	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
FD63_11030	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
FD63_11045	ENOG4105CJ3	phosphate transporter
FD63_11070	ENOG4105DEN	Luciferase family
FD63_11075	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
FD63_11080	ENOG4105C72	UPF0176 protein
FD63_11100	ENOG4105BZU	Histidine kinase
FD63_11110	ENOG4105CBC	glutamate synthase
FD63_11115	ENOG4107QQG	Dehydrogenase
FD63_11125	ENOG4105ETE	Transcriptional regulator (LacI family
FD63_11130	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
FD63_11135	ENOG4105DE4	1-phosphofructokinase
FD63_11140	ENOG4105DM4	PTS System
FD63_11150	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
FD63_11175	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
FD63_11250	ENOG4105CC0	LysR family Transcriptional regulator
FD63_11255	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
FD63_11285	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
FD63_11290	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
FD63_11295	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
FD63_11330	ENOG4105PDP	Short chain dehydrogenase
FD63_11345	ENOG4105CI2	imidazolone-5-propionate hydrolase
FD63_11350	ENOG4105C84	Histidine ammonia-lyase
FD63_11360	ENOG4105CGP	Urocanate hydratase
FD63_11375	ENOG4105U5Y	Transcriptional regulator
FD63_11390	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
FD63_11395	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
FD63_11405	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
FD63_11410	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
FD63_11415	ENOG4105CIH	Imidazole acetol-phosphate transaminase
FD63_11420	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
FD63_11430	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
FD63_11435	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
FD63_11440	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
FD63_11450	ENOG4108Z4V	iron-sulfur cluster assembly
FD63_11475	ENOG4105WH1	Two component transcriptional regulator luxr family
FD63_11520	ENOG41077A9	carbonic anhydrase
FD63_11525	ENOG4105C3W	Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate (By similarity)
FD63_11535	ENOG4105CKY	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively (By similarity)
FD63_11540	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
FD63_11545	ENOG4105CJB	Exodeoxyribonuclease I
FD63_11570	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
FD63_11575	ENOG4105F2I	Transposase
FD63_11630	ENOG4108HRK	Histidine kinase
FD63_11635	ENOG4105EWT	decarboxylase family
FD63_11640	ENOG4108KPZ	tonB-dependent Receptor
FD63_11645	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
FD63_11650	ENOG4107SEV	1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase
FD63_11655	ENOG4105M2J	Glutaredoxin
FD63_11660	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
FD63_11665	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
FD63_11670	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
FD63_11680	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
FD63_11695	ENOG4105KB2	stringent starvation protein b
FD63_11700	ENOG4107MKT	Stringent starvation protein a
FD63_11705	ENOG4105EIX	cytochrome c1
FD63_11715	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
FD63_11720	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
FD63_11725	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
FD63_11730	ENOG4108K3A	Glutathione S-transferase
FD63_11735	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
FD63_11740	ENOG4105C9A	Phoh family
FD63_11755	ENOG4108JU5	Magnesium and cobalt efflux protein
FD63_11765	ENOG4105D7N	magnesium and cobalt transport protein CorA
FD63_11770	ENOG4105C26	Dehydrogenase
FD63_11780	ENOG4105D38	putrescine abc transporter
FD63_11785	ENOG4105F38	ABC transporter, permease
FD63_11790	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
FD63_11820	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
FD63_11825	ENOG4105CFQ	glutamine synthetase
FD63_11830	ENOG4108Z86	Glutamine amidotransferase
FD63_11835	ENOG4105CFQ	glutamine synthetase
FD63_11840	ENOG4105CJP	fad dependent oxidoreductase
FD63_11845	ENOG4105BZU	Histidine kinase
FD63_11850	ENOG4105CSH	Transporter
FD63_11865	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
FD63_11870	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
FD63_11875	ENOG4105FCD	Major Facilitator
FD63_11895	ENOG4105C26	Dehydrogenase
FD63_11900	ENOG4107VRI	Transcriptional regulator
FD63_11905	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
FD63_11910	ENOG4105DCF	alanine dehydrogenase
FD63_11915	ENOG4105C26	Dehydrogenase
FD63_11930	ENOG4106BRA	Membrane
FD63_11935	ENOG4105BZU	Histidine kinase
FD63_11940	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
FD63_11945	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
FD63_11980	ENOG4105KHC	sulfurtransferase
FD63_11990	ENOG4108V1T	peptidylprolyl cis-trans isomerase
FD63_11995	ENOG4105E39	Enoyl-CoA hydratase
FD63_12005	ENOG4105CSM	endonuclease III
FD63_12015	ENOG4107B2H	carbonic anhydrase
FD63_12030	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
FD63_12035	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
FD63_12040	ENOG4105C8U	phosphate abc transporter
FD63_12045	ENOG4105E2Z	phosphate ABC transporter (Permease
FD63_12050	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
FD63_12055	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
FD63_12065	ENOG4105E18	UPF0276 protein
FD63_12075	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
FD63_12095	ENOG4105C2N	RNA methyltransferase TrmH family group 3
FD63_12105	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
FD63_12140	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
FD63_12145	ENOG4105CW7	secretion protein, HlyD family
FD63_12165	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
FD63_12170	ENOG4108UWD	Iron-storage protein
FD63_12185	ENOG4105CAQ	asparagine synthetase
FD63_12195	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
FD63_12200	ENOG4105KUZ	arsenate reductase
FD63_12210	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
FD63_12215	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
FD63_12255	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
FD63_12260	ENOG4105BZU	Histidine kinase
FD63_12265	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
FD63_12270	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
FD63_12275	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
FD63_12280	ENOG4105KNE	Phosphatidate cytidylyltransferase
FD63_12290	ENOG4105DZP	Membrane-associated zinc metalloprotease
FD63_12300	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
FD63_12305	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
FD63_12310	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
FD63_12315	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
FD63_12320	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
FD63_12330	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
FD63_12340	ENOG4108YXA	Membrane
FD63_12430	ENOG4105BZ1	(ABC) transporter
FD63_12450	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
FD63_12460	ENOG4105CAX	The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity)
FD63_12470	ENOG4105BZU	Histidine kinase
FD63_12475	ENOG4105FE9	pseudouridine synthase
FD63_12560	ENOG4105UGU	tonB-dependent Receptor
FD63_12580	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
FD63_12585	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
FD63_12590	ENOG4105C7W	Xanthine dehydrogenase
FD63_12635	ENOG4105MYN	Zinc uptake regulation protein
FD63_12670	ENOG4105EB3	Histidine kinase
FD63_12680	ENOG4105D6S	protein involved in catabolism of external DNA
FD63_12700	ENOG4108JA2	transcriptioN-repair coupling factor
FD63_12710	ENOG4105CBS	Chea signal transduction histidine kinase
FD63_12720	ENOG4105C8Q	Methyl-accepting chemotaxis
FD63_12725	ENOG4105C8Q	Methyl-accepting chemotaxis
FD63_12730	ENOG4108V3W	Chemotaxis protein, CheW
FD63_12735	ENOG4105BZU	Histidine kinase
FD63_12740	ENOG4105BZU	Histidine kinase
FD63_12745	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
FD63_12765	ENOG4105CT4	transporter
FD63_12795	ENOG4105EUB	pirin domain protein
FD63_12800	ENOG4105D22	carbon starvation protein
FD63_12805	ENOG4105VCD	cytoplasmic protein
FD63_12815	ENOG4107UB3	HAD-superfamily hydrolase subfamily IA variant 3
FD63_12835	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
FD63_12840	ENOG4105EPD	Oligopeptide transporter, Opt family
FD63_12845	ENOG4105DUX	Transporter
FD63_12865	ENOG4108UUM	single-stranded DNA-binding protein
FD63_12870	ENOG4105EAH	synthase
FD63_12880	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
FD63_12895	ENOG4105CFH	Aspartokinase
FD63_12900	ENOG4105JAB	phenazine biosynthesis protein, phzf family
FD63_12910	ENOG4108Z9K	Osmotically inducible protein
FD63_12925	ENOG4105DR5	peptidase
FD63_12940	ENOG4107R7Y	intracellular protease Pfpi family
FD63_12960	ENOG4105C3K	feS assembly ATPase SufC
FD63_12965	ENOG4105JRK	feS assembly protein SufD
FD63_12970	ENOG4105C9B	Cysteine desulfurase
FD63_12980	ENOG4105VQD	rieske 2fe-2S domain-containing protein
FD63_12985	ENOG4108ESX	Receptor
FD63_13010	ENOG4105CJ2	(LipO)protein
FD63_13015	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
FD63_13025	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
FD63_13035	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
FD63_13050	ENOG4105EHM	Aminoglycoside phosphotransferase
FD63_13055	ENOG4108S0S	Nucleotidyl transferase
FD63_13065	ENOG4105C02	permease
FD63_13075	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
FD63_13090	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
FD63_13115	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
FD63_13125	ENOG4105C2X	Arabinose 5-phosphate isomerase
FD63_13130	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
FD63_13145	ENOG4108IUZ	ABC transporter
FD63_13150	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
FD63_13155	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
FD63_13160	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
FD63_13165	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
FD63_13170	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
FD63_13180	ENOG41080Z8	PHOSPHOCARRIER protein
FD63_13185	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
FD63_13190	ENOG4105CJW	magnesium transporter
FD63_13210	ENOG4105C85	amino acid
FD63_13220	ENOG4105C8Q	Methyl-accepting chemotaxis
FD63_13240	ENOG4105CXT	aspartate transcarbamylase
FD63_13245	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
FD63_13250	ENOG4108UJU	UPF0301 protein
FD63_13260	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
FD63_13265	ENOG4105CZX	twitching motility protein
FD63_13270	ENOG4105CZX	twitching motility protein
FD63_13275	ENOG4105DFA	alanine racemase domain protein
FD63_13285	ENOG4105II7	pyrroline-5-carboxylate reductase
FD63_13295	ENOG4108Z4X	TRANSCRIPTIONal
FD63_13310	ENOG4105M4B	Catalyzes the transfer of an acetyl group from acetyl- CoA to the 6'-amino group of aminoglycoside molecules conferring resistance to antibiotics containing the purpurosamine ring (By similarity)
FD63_13315	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
FD63_13320	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
FD63_13325	ENOG4105D49	3-dehydroquinate synthase
FD63_13335	ENOG4105BZS	acriflavin resistance protein
FD63_13350	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
FD63_13355	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
FD63_13365	ENOG4105BZU	Histidine kinase
FD63_13375	ENOG4105DS1	cytochrome b561
FD63_13390	ENOG4105EJQ	L-serine dehydratase
FD63_13395	ENOG4105BZU	Histidine kinase
FD63_13405	ENOG4105CFH	Aspartokinase
FD63_13410	ENOG4105C28	cystathionine
FD63_13415	ENOG4106TYC	homoserine o-acetyltransferase (EC 2.3.1.31)
FD63_13425	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
FD63_13430	ENOG4108UT2	hemolysin iii
FD63_13435	ENOG41066T0	asmA family
FD63_13440	ENOG41080XP	Cbs domain
FD63_13450	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
FD63_13455	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
FD63_13495	ENOG4107QPN	acyl-Coa dehydrogenase
FD63_13500	ENOG4106UJV	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
FD63_13525	ENOG4107HY1	Dehydrogenase
FD63_13590	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
FD63_13595	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
FD63_13605	ENOG4107QX8	SPFH domain, Band 7 family protein
FD63_13615	ENOG4105KK4	UPF0060 membrane protein
FD63_13620	ENOG4105DXN	mazG family
FD63_13625	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
FD63_13630	ENOG4107RK2	ADP-ribose diphosphatase NudE
FD63_13640	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
FD63_13650	ENOG4105CHC	glucokinase (EC 2.7.1.2)
FD63_13665	ENOG4105VRS	hydrolase family 18
FD63_13670	ENOG4105E2D	ec 3.2.1.52
FD63_13700	ENOG4105CWX	Alpha-1,2-mannosidase
FD63_13735	ENOG4105CMM	transposase
FD63_13785	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
FD63_13860	ENOG4105CMM	transposase
FD63_14010	ENOG4105CS6	Rhs element vgr protein
FD63_14085	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
FD63_14095	ENOG4105CSR	polyphosphate kinase 2
FD63_14115	ENOG4107S2Z	UPF0761 membrane protein
FD63_14120	ENOG4105CS1	NAD(P)H quinone oxidoreductase
FD63_14135	ENOG4108Z66	YbaK ebsC protein
FD63_14145	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
FD63_14150	ENOG4105CM2	brancheD-chain amino acid aminotransferase
FD63_14165	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
FD63_14170	ENOG4105W8H	transhydrogenase (subunit alpha
FD63_14190	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
FD63_14210	ENOG4105C2M	dna polymerase I
FD63_14250	ENOG4105CMM	transposase
FD63_14275	ENOG4107RNH	Outer membrane receptor FepA
FD63_14290	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
FD63_14305	ENOG4105GAV	receptor
FD63_14315	ENOG4105DJU	Siderophore biosynthesis protein
FD63_14325	ENOG4105DBM	Siderophore biosynthesis protein
FD63_14330	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
FD63_14340	ENOG4105VIF	phosphate starvation-inducible protein
FD63_14360	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
FD63_14400	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
FD63_14410	ENOG4108K4C	ec 3.1.3.12
FD63_14415	ENOG4105BZP	glycoside hydrolase 15-related
FD63_14420	ENOG4105C1K	alpha-alpha-trehalose-phosphate synthase
FD63_14425	ENOG4105DZG	Dehydrogenase
FD63_14445	ENOG4105C8Q	Methyl-accepting chemotaxis
FD63_14460	ENOG4105C34	Pseudouridine synthase
FD63_14465	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FD63_14475	ENOG4108IJ8	ABC transporter
FD63_14480	ENOG4105E90	ABC transporter
FD63_14505	ENOG4105C4K	Nad synthetase
FD63_14520	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
FD63_14530	ENOG4107TUY	Histidine kinase
FD63_14535	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FD63_14545	ENOG4105MZU	cell filamentation protein
FD63_14550	ENOG4107QHF	type ii secretion system protein e
FD63_14560	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
FD63_14570	ENOG4105BZU	Histidine kinase
FD63_14575	ENOG4105ETX	regulatoR
FD63_14585	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
FD63_14620	ENOG4105C28	cystathionine
FD63_14645	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
FD63_14650	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
FD63_14655	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
FD63_14675	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
FD63_14690	ENOG4105ETE	Transcriptional regulator (LacI family
FD63_14705	ENOG4105C2N	RNA methyltransferase TrmH family group 3
FD63_14715	ENOG4105BZG	amino acid carrier protein
FD63_14735	ENOG4105C8Q	Methyl-accepting chemotaxis
FD63_14740	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
FD63_14745	ENOG4105C11	sulfate adenylyltransferase), subunit 2
FD63_14750	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
FD63_14755	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
FD63_14760	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
FD63_14790	ENOG4105K89	arsenate reductase
FD63_14795	ENOG4105BZU	Histidine kinase
FD63_14805	ENOG4107R11	Transcriptional regulator
FD63_14810	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
FD63_14825	ENOG4105C5R	Aminotransferase
FD63_14850	ENOG4105DU0	nucleoside hydrolase
FD63_14870	ENOG4107R1Y	fructose-bisphosphate aldolase
FD63_14875	ENOG4105CA9	Pyruvate kinase
FD63_14885	ENOG4105BZA	Phosphoglycerate kinase
FD63_14900	ENOG4108NVR	Methyl-accepting chemotaxis
FD63_14920	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
FD63_14925	ENOG4105EIF	outer membrane protein W
FD63_14930	ENOG4105EIF	outer membrane protein W
FD63_14945	ENOG41080HT	Transcriptional regulator, arsr family
FD63_14955	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
FD63_14960	ENOG4105E0C	molybdate abc transporter
FD63_14965	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
FD63_14990	ENOG4108QQZ	ErfK YbiS YcfS YnhG family protein
FD63_14995	ENOG4105DR5	peptidase
FD63_15020	ENOG4105CV1	Transketolase (EC 2.2.1.1)
FD63_15025	ENOG4105CK2	sodium dicarboxylate symporter
FD63_15055	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
FD63_15060	ENOG4105E4G	Type IV pilus
FD63_15100	ENOG4105D9Y	Splits dipeptides with a prolyl residue in the C- terminal position (By similarity)
FD63_15105	ENOG4107RAQ	aminopeptidase
FD63_15115	ENOG4105BZU	Histidine kinase
FD63_15125	ENOG4105W8B	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
FD63_15130	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
FD63_15140	ENOG4105E66	phosphoriboisomerase A
FD63_15155	ENOG4105VCQ	rubredoxin
FD63_15160	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
FD63_15185	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
FD63_15200	ENOG41090JD	Blue (Type 1) copper domain protein
FD63_15210	ENOG4107TJ9	Cytochrome
FD63_15220	ENOG4105C8Y	Acetylornithine aminotransferase
FD63_15230	ENOG4105DKQ	ROK family
FD63_15245	ENOG410841Q	phosphoesterase PA-phosphatase related protein
FD63_15255	ENOG4105DFU	Cell wall formation (By similarity)
FD63_15260	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
FD63_15285	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
FD63_15295	ENOG4105F0N	pyrophosphate phospho-hydrolase
FD63_15310	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
FD63_15320	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
FD63_15335	ENOG4105C7B	Threonine dehydratase
FD63_15340	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
FD63_15350	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
FD63_15360	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
FD63_15365	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
FD63_15370	ENOG4105BZU	Histidine kinase
FD63_15380	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
FD63_15385	ENOG4105DFG	type I secretion outer membrane protein
FD63_15390	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
FD63_15395	ENOG4105D1S	lipid A biosynthesis
FD63_15420	ENOG4108JJA	ABC, transporter
FD63_15440	ENOG4105C6K	Malic enzyme
FD63_15445	ENOG4105CK2	sodium dicarboxylate symporter
FD63_15470	ENOG4106JDA	Phosphoglycerate transport regulatory protein PGTC
FD63_15475	ENOG4105DHQ	Histidine kinase
FD63_15490	ENOG4105D4T	Citrate transporter
FD63_15495	ENOG4105CHR	reductase
FD63_15500	ENOG4105ETE	Transcriptional regulator (LacI family
FD63_15515	ENOG4107QW3	Sucrose phosphorylase
FD63_15535	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
FD63_15540	ENOG4105CHM	Aminotransferase
FD63_15585	ENOG4105CD3	dihydroorotase
FD63_15620	ENOG4105JAB	phenazine biosynthesis protein, phzf family
FD63_15635	ENOG4108QBQ	Catalyzes the condensation of formaldehyde and glutathione to S-hydroxymethylglutathione (By similarity)
FD63_15650	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
FD63_15655	ENOG4105E0F	Histidine kinase
FD63_15690	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
FD63_15695	ENOG4106RE7	Cytochrome
FD63_15725	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
FD63_15735	ENOG4105CE4	GlcNAc 6-P deacetylase
FD63_15740	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
FD63_15745	ENOG4107KJX	Transcriptional regulator
FD63_15750	ENOG4105EDR	glucose galactose transporter
FD63_15755	ENOG4105FDP	GntR family transcriptional regulator
FD63_15770	ENOG4105CNT	hydrolase family 2
FD63_15815	ENOG4105BZU	Histidine kinase
FD63_15825	ENOG4105BZU	Histidine kinase
FD63_15835	ENOG4105W4M	Transport-associated protein
FD63_15840	ENOG4105D9R	oxidoreductase
FD63_15845	ENOG4108J5G	6-phosphogluconate dehydrogenase
FD63_15855	ENOG4105ECP	epimerase
FD63_15875	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
FD63_15880	ENOG4105D6F	Phosphatase
FD63_15905	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
FD63_15915	ENOG4105DXX	methyltransferase
FD63_15940	ENOG4105SYT	Methylenetetrahydrofolate reductase
FD63_15950	ENOG4105M6F	mutator MutT protein
FD63_15965	ENOG4105DR5	peptidase
FD63_15975	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
FD63_15980	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
FD63_15985	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
FD63_15990	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
FD63_15995	ENOG4105CPF	Cell wall formation (By similarity)
FD63_16000	ENOG4105DFU	Cell wall formation (By similarity)
FD63_16005	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
FD63_16015	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
FD63_16020	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
FD63_16025	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
FD63_16030	ENOG4105CJN	penicillin-binding protein
FD63_16035	ENOG4106932	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
FD63_16040	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
FD63_16045	ENOG4108V6E	Cell division protein mraZ
FD63_16075	ENOG4105S2T	inner membrane protein YbcI
FD63_16080	ENOG4105CQB	FAD linked oxidase domain protein
FD63_16085	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
FD63_16090	ENOG4105C08	Histidine kinase
FD63_16095	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
FD63_16100	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
FD63_16105	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
FD63_16130	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
FD63_16135	ENOG4107YIM	Involved in the transcription termination process (By similarity)
FD63_16140	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
FD63_16155	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
FD63_16165	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
FD63_16170	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
FD63_16200	ENOG4105C5H	ABC transporter
FD63_16205	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
FD63_16225	ENOG410802X	bacteriophage n4 adsorption protein b
FD63_16235	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
FD63_16240	ENOG4105EJG	cellulose synthase
FD63_16290	ENOG4108K85	Transcriptional regulator
FD63_16300	ENOG4105GVR	general secretion pathway protein D
FD63_16310	ENOG410678M	general secretion pathway protein M
FD63_16315	ENOG41090VX	general secretion pathway protein L
FD63_16320	ENOG4105UV2	general secretion pathway protein K
FD63_16325	ENOG41069G9	General secretion pathway protein J
FD63_16335	ENOG4105WMT	general secretion pathway protein h
FD63_16345	ENOG4105D7Q	type ii secretion system
FD63_16350	ENOG4107QHF	type ii secretion system protein e
FD63_16355	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
FD63_16375	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
FD63_16380	ENOG4105T95	Thiol disulfide interChange protein
FD63_16385	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
FD63_16410	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
FD63_16415	ENOG4105MYG	DNA polymerase iii, chi subunit
FD63_16430	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
FD63_16450	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
FD63_16465	ENOG4108YX2	DNA-binding protein
FD63_16480	ENOG4105DHJ	ABC, transporter
FD63_16485	ENOG4108SNX	Mammalian cell entry related domain protein
FD63_16500	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
FD63_16515	ENOG4107QP7	CoA-transferase subunit A
FD63_16520	ENOG4107QKV	phosphomannomutase
FD63_16525	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
FD63_16530	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
FD63_16535	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
FD63_16550	ENOG4105BZJ	Electron transfer flavoprotein
FD63_16555	ENOG4105C10	Electron transfer flavoprotein
FD63_16570	ENOG4105IQ5	FAD linked oxidase domain protein
FD63_16575	ENOG4108RG3	short-chain dehydrogenase reductase
FD63_16600	ENOG4105BZ8	glutamate synthase
FD63_16655	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
FD63_16660	ENOG4105EY8	ABC transporter
FD63_16670	ENOG4105C28	cystathionine
FD63_16695	ENOG4105CZX	twitching motility protein
FD63_16700	ENOG4108RXX	maleylacetoacetate isomerase
FD63_16710	ENOG4105C1J	atp-dependent rna helicase
FD63_16715	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
FD63_16740	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
FD63_16745	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
FD63_16750	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
FD63_16755	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
FD63_16775	ENOG4105DGW	oligopeptidase A
FD63_16790	ENOG4105C59	p-type ATPase
FD63_16805	ENOG4105E3B	Multicopper oxidase
FD63_16820	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
FD63_16830	ENOG4105C19	ABC transporter
FD63_16840	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
FD63_16845	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
FD63_16850	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
FD63_16860	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FD63_16865	ENOG4105BZU	Histidine kinase
FD63_16875	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
FD63_16890	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
FD63_16895	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
FD63_16900	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
FD63_16905	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
FD63_16910	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
FD63_16915	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
FD63_16920	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
FD63_16925	ENOG4107RAZ	it plays a direct role in the translocation of protons across the membrane (By similarity)
FD63_16940	ENOG4107QN2	dihydrolipoyl dehydrogenase
FD63_16945	ENOG4107QSN	dihydrolipoamide acetyltransferase
FD63_16970	ENOG4105D01	(LipO)protein
FD63_16975	ENOG4108UMI	ABC transporter, permease
FD63_16980	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
FD63_16985	ENOG4108EHX	EamA-like transporter family
FD63_16990	ENOG4108VPT	UPF0234 protein
FD63_17000	ENOG4105I08	Pseudouridine synthase
FD63_17005	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
FD63_17025	ENOG4105BZU	Histidine kinase
FD63_17050	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
FD63_17055	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
FD63_17060	ENOG4105EW9	transcriptional regulator AsnC family
FD63_17080	ENOG4107RD7	Flagellar Motor Protein, MotA
FD63_17085	ENOG4105ER2	Ompa motb domain protein
FD63_17125	ENOG4105E3A	(ABC) transporter
FD63_17130	ENOG4105DA5	(ABC) transporter
FD63_17135	ENOG4105EEQ	Na H antiporter
FD63_17150	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
FD63_17160	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
FD63_17185	ENOG4108FN7	Aldo keto reductase
FD63_17195	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
FD63_17200	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
FD63_17220	ENOG4105BZU	Histidine kinase
FD63_17270	ENOG41060GT	Translocates 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane (By similarity)
FD63_17280	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
FD63_17290	ENOG4105E0K	tonB-dependent siderophore receptor
FD63_17300	ENOG4108VAC	response regulator
FD63_17330	ENOG4107QTZ	amino acid
FD63_17340	ENOG4106R7G	Glycoside hydrolase family 5
FD63_17360	ENOG4105E4C	Lytic transglycosylase catalytic
FD63_17380	ENOG4105CF7	AraC family transcriptional regulator
FD63_17395	ENOG4107QUT	magnesium and cobalt transport protein CorA
FD63_17405	ENOG4105DFI	Membrane
FD63_17420	ENOG4107QS8	(LipO)protein
FD63_17430	ENOG4108MYR	Secreted protein
FD63_17495	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
FD63_17500	ENOG41069D7	Methyl-accepting chemotaxis
FD63_17515	ENOG4108YYC	ycei family
FD63_17540	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
FD63_17570	ENOG41082IR	Excinuclease ABC C subunit domain protein
FD63_17575	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
FD63_17585	ENOG4105D05	Receptor
FD63_17605	ENOG4105CB5	ATP-dependent DNA helicase recG
FD63_17610	ENOG4105C0D	helicase
FD63_17615	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
FD63_17620	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
FD63_17625	ENOG4105VF7	tolerance protein
FD63_17630	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
FD63_17635	ENOG4107USA	Thioredoxin
FD63_17650	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
FD63_17655	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
FD63_17660	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
FD63_17680	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
FD63_17700	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
FD63_17710	ENOG4108HPI	phosphatidate Cytidylyltransferase
FD63_17730	ENOG4105E8V	Alpha Beta Hydrolase Fold protein
FD63_17745	ENOG4105DC1	bifunctional purine biosynthesis protein purh
FD63_17750	ENOG4105C12	Phosphoribosylglycinamide synthetase
FD63_17765	ENOG4105EM2	membrane
FD63_17810	ENOG4105E09	nadh pyrophosphatase
FD63_17815	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
FD63_17840	ENOG4105BZU	Histidine kinase
FD63_17845	ENOG4108UQY	Iron-storage protein
FD63_17850	ENOG4105W53	bacterioferritin-associated ferredoxin
FD63_17855	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
FD63_17870	ENOG4108UJD	30S ribosomal protein S9
FD63_17875	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
FD63_17880	ENOG4108S0N	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol (By similarity)
FD63_17895	ENOG4105FDS	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
FD63_17900	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
FD63_17905	ENOG410635A	Membrane
FD63_17920	ENOG4105DK0	Indole-3-glycerol phosphate synthase
FD63_17925	ENOG4108I0Q	anthranilate phosphoribosyltransferase
FD63_17935	ENOG4105DDQ	anthranilate synthase
FD63_17945	ENOG4105CRQ	synthase (Component I)
FD63_17950	ENOG4107TE5	Lipid kinase
FD63_17965	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
FD63_17970	ENOG4105C8V	SAICAR synthetase
FD63_17980	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
FD63_17985	ENOG4105D65	subunit l
FD63_17990	ENOG4108ZE9	Monovalent cation H antiporter subunit C
FD63_17995	ENOG4107R4Z	monovalent cation h antiporter subunit d
FD63_18000	ENOG4105SC1	monovalent cation H antiporter subunit E
FD63_18005	ENOG4105W4C	monovalent cation H antiporter subunit F
FD63_18010	ENOG4105KJM	monovalent cation h antiporter subunit g
FD63_18015	ENOG4105FEU	K -dependent Na -Ca exchanger
FD63_18050	ENOG4105DUX	Transporter
FD63_18055	ENOG4105HJ8	Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity)
FD63_18070	ENOG4107RUY	(E1 component), alpha subunit
FD63_18075	ENOG4105CPP	Dehydrogenase, E1 component
FD63_18085	ENOG4105C7S	Dehydrogenase
FD63_18115	ENOG4105C1J	atp-dependent rna helicase
FD63_18130	ENOG4105D7K	pfkb domain protein
FD63_18135	ENOG4105FSR	swimming returnes to normal when residues 206-207 are both mutated to Ala. Overexpression also leads to a reduction in flagellar abundance and a 20-fold increase in c-di- GMP levels in vivo. Required for aminoglycoside-mediated induction of biofilm formation, it also plays a lesser role in biofilm production in response to other classes of translation inhibitors. The c-di-GMP produced by this enzyme up-regulates poly-GlcNAc production as well as the biofilm synthesis protein PgaD, although c-di-GMP is probably not the main inducing principle. Cyclic-di- GMP is a second messenger which controls cell surface-associated traits in bacteria
FD63_18140	ENOG4105CKW	Inner membrane protein yedI
FD63_18160	ENOG4105EGS	Mechanosensitive ion channel
FD63_18170	ENOG4105D6F	Phosphatase
FD63_18185	ENOG4108KPJ	rna polymerase sigma factor
FD63_18200	ENOG4105DRR	Transcriptional regulator, GntR family
FD63_18215	ENOG4108K6F	triphosphoribosyl-dephospho-CoA synthase
FD63_18220	ENOG41065ZS	Transfers 2'-(5-triphosphoribosyl)-3'-dephosphocoenzyme- A to the apo- acyl-carrier-protein of the malonate decarboxylase to yield holo- acyl-carrier-protein (By similarity)
FD63_18235	ENOG4105WSE	Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism (By similarity)
FD63_18245	ENOG4108K2P	TRANSCRIPTIONal
FD63_18250	ENOG4105EDR	glucose galactose transporter
FD63_18255	ENOG4105QJH	Domain of unknown function (DUF718)
FD63_18260	ENOG4105DIA	mandelate racemase muconate lactonizing
FD63_18265	ENOG4105ERH	Fumarylacetoacetate hydrolase
FD63_18270	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
FD63_18285	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
FD63_18305	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
FD63_18310	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
FD63_18315	ENOG4105E98	transcriptional regulator DeoR family
FD63_18320	ENOG4108W15	Protein of unknown function (DUF1456)
FD63_18365	ENOG4105C5Z	peptidase
FD63_18380	ENOG4105E0K	tonB-dependent siderophore receptor
FD63_18425	ENOG4105C0H	protease
FD63_18445	ENOG4105C02	permease
FD63_18450	ENOG4107URF	beta-phospho-glucomutase
FD63_18455	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
FD63_18465	ENOG4107VGR	Catalase
FD63_18490	ENOG4105C19	ABC transporter
FD63_18495	ENOG4107RBB	ABC transporter, permease
FD63_18510	ENOG4105FR1	rard protein
FD63_18515	ENOG4105FDR	Membrane
FD63_18530	ENOG4105C31	Tryptophanyl-tRNA synthetase
FD63_18570	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
FD63_18580	ENOG4105EXZ	Involved in the regulation of ptsG expression by binding and inactivating Mlc (By similarity)
FD63_18595	ENOG4105EB3	Histidine kinase
FD63_18600	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
FD63_18610	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
FD63_18645	ENOG4106KE4	Dehydrogenase
FD63_18650	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
FD63_18655	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
FD63_18675	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
FD63_18680	ENOG4105D94	Major Facilitator Superfamily
FD63_18685	ENOG4106NZI	LysR family Transcriptional regulator
FD63_18695	ENOG4105CMM	transposase
FD63_18720	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
FD63_18725	ENOG4107QYD	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
FD63_18735	ENOG4108ZHJ	Organic hydroperoxide resistance protein
FD63_18740	ENOG4105K56	Transcriptional regulator
FD63_18745	ENOG4105D6Z	AFG1 family ATPase
FD63_18755	ENOG4108TZV	Membrane
FD63_18765	ENOG4105CKI	cobalamin synthesis protein
FD63_18775	ENOG4105KK4	UPF0060 membrane protein
FD63_18780	ENOG4105MPD	Cytochrome
FD63_18790	ENOG4105C1G	acyl-Coa dehydrogenase
FD63_18795	ENOG4107QX3	carboxylase
FD63_18820	ENOG4105CD5	CoA-binding domain protein
FD63_18825	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
FD63_18830	ENOG4105BZP	glycoside hydrolase 15-related
FD63_18840	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
FD63_18855	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
FD63_18865	ENOG4105VNG	YcgL domain-containing protein
FD63_18870	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
FD63_18880	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
FD63_18890	ENOG4105C2D	reductase
FD63_18915	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
FD63_18930	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
FD63_18955	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
FD63_18960	ENOG4105C4M	(Ubiquinol oxidase) subunit I
FD63_18980	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
FD63_18990	ENOG4107VMU	Membrane
FD63_18995	ENOG4105C2M	dna polymerase I
FD63_19010	ENOG4107YZX	Universal stress protein
FD63_19030	ENOG4105C4R	Atp-dependent dna helicase
FD63_19040	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
FD63_19045	ENOG4105W0E	50S ribosomal protein L33
FD63_19050	ENOG4105KDC	50s ribosomal protein l28
FD63_19075	ENOG4105CKK	Glycosyl transferase, family 2
FD63_19085	ENOG4105FA0	parb-like partition protein
FD63_19090	ENOG4107QJE	Chromosome Partitioning Protein
FD63_19095	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
FD63_19140	ENOG4107RGH	Aldehyde dehydrogenase
FD63_19150	ENOG4105CSH	Transporter
FD63_19160	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
FD63_19170	ENOG4108UI1	Probably functions as a manganese efflux pump (By similarity)
FD63_19180	ENOG4105BZU	Histidine kinase
FD63_19195	ENOG4105E2V	Glycosyltransferase 36
FD63_19200	ENOG4105CT4	transporter
FD63_19205	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
FD63_19210	ENOG4105C1K	alpha-alpha-trehalose-phosphate synthase
FD63_19225	ENOG4105MA0	exported protein
FD63_19230	ENOG4105CFU	surface antigen
FD63_19250	ENOG4108YXG	UPF0502 protein
FD63_19265	ENOG4105CMM	transposase
FD63_19280	ENOG4105CMM	transposase
FD63_19305	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
FD63_19310	ENOG4105QV4	Tryptophan halogenase
FD63_19320	ENOG4105ETE	Transcriptional regulator (LacI family
FD63_19330	ENOG4105E55	glycerol-3-phosphate acyltransferase
FD63_19355	ENOG4105DT9	hydrolase family 43
FD63_19360	ENOG4105CT4	transporter
FD63_19380	ENOG4105D9F	endo-1,4-beta-xylanase (EC 3.2.1.8)
FD63_19405	ENOG4105CMM	transposase
FD63_19410	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
FD63_19425	ENOG4105DEI	Mannitol dehydrogenase
FD63_19440	ENOG4105CXK	mandelate racemase muconate lactonizing
FD63_19450	ENOG4105D0H	Alpha-glucuronidase (EC 3.2.1.139)
FD63_19455	ENOG4105ETE	Transcriptional regulator (LacI family
FD63_19460	ENOG4105C93	Xylose Isomerase
FD63_19465	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
FD63_19470	ENOG4105DH7	May be involved in recombination (By similarity)
FD63_19490	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
FD63_19505	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
FD63_19510	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
FD63_19520	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
FD63_19525	ENOG4107QHF	type ii secretion system protein e
FD63_19530	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
FD63_19545	ENOG4105C4R	Atp-dependent dna helicase
FD63_19550	ENOG4107104	thymidine kinase
FD63_19565	ENOG4105DJ9	glucan biosynthesis protein
FD63_19575	ENOG4105D9P	serine threonine protein kinase
FD63_19590	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
FD63_19605	ENOG4105DKW	ABC transporter
FD63_19620	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
FD63_19625	ENOG41067YR	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)