locus-tag	class	description
FD63_00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FD63_00020	COG0187	DNA topoisomerase II activity
FD63_00025	COG1266	CAAX protease self-immunity
FD63_00030	COG0501	Belongs to the peptidase M48B family
FD63_00075	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FD63_00095	COG1280	lysine exporter protein (LysE YggA)
FD63_00110	COG4772	TonB-dependent receptor
FD63_00120	COG3284	Transcriptional regulator
FD63_00125	COG1012	belongs to the aldehyde dehydrogenase family
FD63_00160	COG1304	FMN binding
FD63_00190	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FD63_00240	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FD63_00270	COG4771	TonB-dependent receptor
FD63_00315	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FD63_00330	COG3507	Belongs to the glycosyl hydrolase 43 family
FD63_00335	COG1609	Transcriptional regulator
FD63_00345	COG1028	Short-chain dehydrogenase reductase Sdr
FD63_00365	COG3186	Phenylalanine-4-hydroxylase
FD63_00370	COG1522	sequence-specific DNA binding
FD63_00395	COG1752	Esterase of the alpha-beta hydrolase superfamily
FD63_00415	COG0671	phosphoesterase, PA-phosphatase related
FD63_00430	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FD63_00470	COG1929	Belongs to the glycerate kinase type-1 family
FD63_00480	COG0531	amino acid
FD63_00485	COG4566	intracellular signal transduction
FD63_00490	COG4191	Histidine kinase
FD63_00510	COG1322	Protein conserved in bacteria
FD63_00515	COG0386	Belongs to the glutathione peroxidase family
FD63_00520	COG2853	Lipoprotein
FD63_00535	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FD63_00540	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FD63_00545	COG1127	ABC transporter
FD63_00550	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
FD63_00555	COG1074	ATP-dependent DNA helicase activity
FD63_00560	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FD63_00580	COG0537	adenosine 5'-monophosphoramidase activity
FD63_00655	COG0477	Major facilitator Superfamily
FD63_00660	COG0302	gtp cyclohydrolase
FD63_00685	COG0730	response to heat
FD63_00690	COG3012	SEC-C Motif Domain Protein
FD63_00700	COG0676	glucose-6-phosphate 1-epimerase activity
FD63_00760	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
FD63_00765	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
FD63_00770	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
FD63_00775	COG0493	'glutamate synthase
FD63_00780	COG0070	glutamate synthase
FD63_00780	COG0069	glutamate synthase activity
FD63_00780	COG0067	glutamate synthase
FD63_00830	COG1111	helicase
FD63_00830	COG1205	dead DEAH box helicase
FD63_00835	COG2963	transposase activity
FD63_00840	COG2801	Transposase and inactivated derivatives
FD63_00880	COG2271	Major facilitator Superfamily
FD63_00925	COG1192	Involved in chromosome partitioning
FD63_00930	COG2062	phosphohistidine phosphatase, SixA
FD63_00940	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FD63_00945	COG2050	protein possibly involved in aromatic compounds catabolism
FD63_00955	COG2267	carboxylic ester hydrolase activity
FD63_00965	COG1881	PFAM PEBP family protein
FD63_00970	COG1968	undecaprenyl-diphosphatase activity
FD63_00975	COG0174	glutamine synthetase
FD63_00980	COG0347	Belongs to the P(II) protein family
FD63_00985	COG0004	ammonium transporteR
FD63_00995	COG3852	Histidine kinase
FD63_01000	COG2204	response regulator
FD63_01005	COG2032	superoxide dismutase activity
FD63_01010	COG2032	superoxide dismutase activity
FD63_01020	COG0183	Belongs to the thiolase family
FD63_01060	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FD63_01065	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FD63_01075	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FD63_01085	COG0612	Peptidase, M16
FD63_01095	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FD63_01105	COG0596	Alpha beta hydrolase
FD63_01120	COG0318	PFAM AMP-dependent synthetase and ligase
FD63_01135	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FD63_01145	COG1181	Belongs to the D-alanine--D-alanine ligase family
FD63_01165	COG0564	pseudouridine synthase activity
FD63_01185	COG0339	signal peptide processing
FD63_01210	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FD63_01215	COG2224	Isocitrate lyase
FD63_01220	COG3706	GGDEF domain
FD63_01250	COG0659	secondary active sulfate transmembrane transporter activity
FD63_01285	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FD63_01290	COG2130	NADP-dependent
FD63_01305	COG1187	pseudouridine synthase activity
FD63_01315	COG1643	Atp-dependent helicase
FD63_01320	COG0084	hydrolase, TatD family'
FD63_01335	COG0842	Transport permease protein
FD63_01340	COG1131	(ABC) transporter
FD63_01345	COG0633	Ferredoxin
FD63_01345	COG0543	2 iron, 2 sulfur cluster binding
FD63_01355	COG1476	TRANSCRIPTIONal
FD63_01365	COG4555	ABC transporter
FD63_01385	COG0625	glutathione transferase activity
FD63_01460	COG1199	ATP-dependent helicase activity
FD63_01520	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FD63_01545	COG0628	permease
FD63_01560	COG2133	pyrroloquinoline quinone binding
FD63_01595	COG0754	glutathionylspermidine amidase activity
FD63_01605	COG0714	Associated with various cellular activities
FD63_01650	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FD63_01665	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FD63_01670	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FD63_01695	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FD63_01715	COG1028	Short-chain dehydrogenase reductase Sdr
FD63_01725	COG0156	8-amino-7-oxononanoate synthase activity
FD63_01730	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FD63_01740	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FD63_01775	COG0606	chelatase, subunit chli
FD63_01780	COG2960	long-chain fatty acid transporting porin activity
FD63_01800	COG1166	arginine decarboxylase activity
FD63_01805	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FD63_01815	COG2755	lipolytic protein G-D-S-L family
FD63_01815	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FD63_01820	COG0583	DNA-binding transcription factor activity
FD63_01840	COG4221	oxidoreductase activity
FD63_01855	COG2003	Belongs to the UPF0758 family
FD63_01860	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FD63_01880	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FD63_01890	COG2814	Major facilitator Superfamily
FD63_01905	COG0739	heme binding
FD63_01910	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FD63_01940	COG1064	alcohol dehydrogenase
FD63_01945	COG2234	aminopeptidase activity
FD63_01955	COG4942	peptidase
FD63_01960	COG0793	Belongs to the peptidase S41A family
FD63_02020	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FD63_02030	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
FD63_02060	COG0109	protoheme IX farnesyltransferase activity
FD63_02075	COG0358	DNA primase activity
FD63_02080	COG1295	ribonuclease BN
FD63_02090	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FD63_02100	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FD63_02105	COG2308	Evidence 4 Homologs of previously reported genes of
FD63_02125	COG2133	pyrroloquinoline quinone binding
FD63_02145	COG0531	amino acid
FD63_02160	COG4948	Mandelate Racemase Muconate Lactonizing
FD63_02170	COG4771	TonB-dependent receptor
FD63_02175	COG3023	N-Acetylmuramoyl-L-alanine amidase
FD63_02225	COG5383	Protein conserved in bacteria
FD63_02245	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FD63_02250	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FD63_02265	COG1652	LysM domain
FD63_02325	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FD63_02330	COG3118	belongs to the thioredoxin family
FD63_02340	COG2884	Cell division ATP-binding protein ftsE
FD63_02345	COG2177	Part of the ABC transporter FtsEX involved in
FD63_02350	COG2201	protein-glutamate methylesterase activity
FD63_02355	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FD63_02360	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FD63_02365	COG2860	membrane
FD63_02370	COG1252	NADH dehydrogenase
FD63_02380	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FD63_02395	COG0534	Mate efflux family protein
FD63_02400	COG0616	signal peptide processing
FD63_02410	COG1028	Short-chain dehydrogenase reductase Sdr
FD63_02425	COG0009	L-threonylcarbamoyladenylate synthase
FD63_02430	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FD63_02430	COG1754	DNA topoisomerase type I activity
FD63_02435	COG1714	RDD family
FD63_02450	COG0758	DNA mediated transformation
FD63_02455	COG1652	LysM domain
FD63_02460	COG0242	peptide deformylase activity
FD63_02465	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FD63_02470	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FD63_02470	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FD63_02475	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FD63_02510	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FD63_02515	COG1247	-acetyltransferase
FD63_02525	COG1490	D-aminoacyl-tRNA deacylase activity
FD63_02530	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FD63_02550	COG2963	transposase activity
FD63_02565	COG1609	Transcriptional regulator
FD63_02575	COG0366	Alpha amylase catalytic
FD63_02580	COG0366	Alpha amylase catalytic
FD63_02605	COG2801	Transposase and inactivated derivatives
FD63_02610	COG2963	transposase activity
FD63_02645	COG1309	transcriptional regulator
FD63_02685	COG0840	transmembrane signaling receptor activity
FD63_02700	COG3546	catalase activity
FD63_02705	COG3685	Protein conserved in bacteria
FD63_02710	COG3685	Protein conserved in bacteria
FD63_02715	COG1028	Short-chain dehydrogenase reductase Sdr
FD63_02725	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
FD63_02740	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FD63_02755	COG0028	Belongs to the TPP enzyme family
FD63_02760	COG4191	Histidine kinase
FD63_02790	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FD63_02805	COG3645	SOS response
FD63_02825	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FD63_02825	COG1648	precorrin-2 dehydrogenase activity
FD63_02835	COG1116	anion transmembrane transporter activity
FD63_02835	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FD63_02840	COG2223	nitrite transmembrane transporter activity
FD63_02845	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FD63_02850	COG2146	nitrite reductase [NAD(P)H] activity
FD63_02855	COG0243	molybdopterin cofactor binding
FD63_02885	COG1640	4-alpha-glucanotransferase
FD63_02890	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FD63_02900	COG0297	glycogen (starch) synthase activity
FD63_02910	COG0745	RESPONSE REGULATOR receiver
FD63_02940	COG0181	hydroxymethylbilane synthase activity
FD63_02955	COG1733	regulation of RNA biosynthetic process
FD63_02970	COG1505	serine-type exopeptidase activity
FD63_02995	COG2832	Protein of unknown function (DUF454)
FD63_03005	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FD63_03025	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FD63_03050	COG2226	methyltransferase
FD63_03055	COG0308	aminopeptidase N
FD63_03060	COG0508	dehydrogenase complex catalyzes the overall conversion of
FD63_03060	COG0596	Alpha beta hydrolase
FD63_03085	COG1077	Cell shape determining protein MreB Mrl
FD63_03090	COG1792	Involved in formation and maintenance of cell shape
FD63_03100	COG0768	penicillin binding
FD63_03105	COG0772	Belongs to the SEDS family
FD63_03125	COG2951	lytic endotransglycosylase activity
FD63_03135	COG1686	Belongs to the peptidase S11 family
FD63_03165	COG2921	Belongs to the UPF0250 family
FD63_03170	COG0321	lipoyl(octanoyl) transferase activity
FD63_03175	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FD63_03200	COG1056	cytidyltransferase-related domain
FD63_03200	COG1051	belongs to the nudix hydrolase family
FD63_03235	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FD63_03240	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FD63_03245	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FD63_03250	COG1561	YicC-like family, N-terminal region
FD63_03255	COG0194	GDP metabolic process
FD63_03260	COG1758	RNA polymerase activity
FD63_03265	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FD63_03280	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FD63_03290	COG0254	rRNA binding
FD63_03295	COG0372	Belongs to the citrate synthase family
FD63_03310	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FD63_03330	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FD63_03335	COG0667	Aldo Keto reductase
FD63_03345	COG4771	TonB-dependent receptor
FD63_03365	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
FD63_03370	COG4181	ATPase activity
FD63_03385	COG0642	Histidine kinase
FD63_03395	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FD63_03400	COG0861	Integral membrane protein TerC family
FD63_03405	COG1704	LemA family
FD63_03435	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FD63_03440	COG2967	ApaG domain
FD63_03445	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FD63_03455	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FD63_03460	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FD63_03465	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FD63_03475	COG2096	Adenosyltransferase
FD63_03485	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FD63_03490	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FD63_03530	COG0697	spore germination
FD63_03535	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FD63_03555	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FD63_03560	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FD63_03565	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FD63_03575	COG0583	DNA-binding transcription factor activity
FD63_03580	COG3634	alkyl hydroperoxide reductase activity
FD63_03610	COG0488	(ABC) transporter
FD63_03660	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FD63_03665	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FD63_03680	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FD63_03690	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FD63_03700	COG0193	aminoacyl-tRNA hydrolase activity
FD63_03705	COG0012	GTP binding
FD63_03725	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FD63_03735	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FD63_03740	COG0250	Participates in transcription elongation, termination and antitermination
FD63_03745	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FD63_03750	COG0081	regulation of translation
FD63_03760	COG0222	ribosome binding
FD63_03770	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FD63_03785	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FD63_03790	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FD63_03795	COG0051	transcription antitermination factor activity, RNA binding
FD63_03805	COG0088	Forms part of the polypeptide exit tunnel
FD63_03810	COG0089	rRNA binding
FD63_03815	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FD63_03825	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FD63_03840	COG0255	Belongs to the universal ribosomal protein uL29 family
FD63_03845	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FD63_03850	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FD63_03855	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FD63_03860	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FD63_03865	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FD63_03885	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FD63_03890	COG1841	ribosomal large subunit assembly
FD63_03900	COG0201	protein transport
FD63_03905	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FD63_03910	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FD63_03915	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FD63_03920	COG0202	RNA polymerase activity
FD63_03925	COG0203	ribosomal protein L17
FD63_03930	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FD63_03940	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
FD63_03960	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FD63_03970	COG0039	L-malate dehydrogenase activity
FD63_03990	COG0625	glutathione transferase activity
FD63_04035	COG0446	pyridine nucleotide-disulphide oxidoreductase
FD63_04035	COG1902	pentaerythritol trinitrate reductase activity
FD63_04045	COG0667	Aldo Keto reductase
FD63_04070	COG2885	chlorophyll binding
FD63_04090	COG0156	8-amino-7-oxononanoate synthase activity
FD63_04095	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FD63_04100	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FD63_04105	COG4208	sulfate ABC transporter
FD63_04110	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FD63_04130	COG0588	phosphoglycerate mutase activity
FD63_04135	COG0285	dihydrofolate synthase activity
FD63_04155	COG2833	Protein of unknown function (DUF455)
FD63_04160	COG3291	Pkd domain containing protein
FD63_04180	COG0438	transferase activity, transferring glycosyl groups
FD63_04185	COG0248	Ppx GppA phosphatase
FD63_04190	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FD63_04205	COG4783	chaperone-mediated protein folding
FD63_04220	COG0473	3-isopropylmalate dehydrogenase activity
FD63_04260	COG0544	peptidyl-prolyl cis-trans isomerase activity
FD63_04265	COG0740	serine-type endopeptidase activity
FD63_04270	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FD63_04310	COG1388	LysM domain
FD63_04310	COG3942	CHAP domain
FD63_04315	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FD63_04325	COG0328	RNA-DNA hybrid ribonuclease activity
FD63_04330	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FD63_04335	COG0631	protein serine/threonine phosphatase activity
FD63_04355	COG0859	PFAM glycosyl transferase family 9
FD63_04365	COG1234	tRNA 3'-trailer cleavage
FD63_04370	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FD63_04385	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
FD63_04390	COG0314	molybdopterin synthase activity
FD63_04410	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FD63_04420	COG0537	adenosine 5'-monophosphoramidase activity
FD63_04440	COG0714	Associated with various cellular activities
FD63_04465	COG1399	metal-binding, possibly nucleic acid-binding protein
FD63_04470	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FD63_04475	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FD63_04480	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FD63_04485	COG1028	Short-chain dehydrogenase reductase Sdr
FD63_04500	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FD63_04505	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FD63_04510	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FD63_04530	COG4115	mRNA cleavage
FD63_04535	COG2161	toxin-antitoxin pair type II binding
FD63_04570	COG0587	DNA-directed DNA polymerase activity
FD63_04585	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FD63_04590	COG0372	Belongs to the citrate synthase family
FD63_04605	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FD63_04630	COG2373	Large extracellular alpha-helical protein
FD63_04650	COG4953	penicillin-binding protein 1C
FD63_04660	COG0678	peroxiredoxin activity
FD63_04680	COG0604	alcohol dehydrogenase
FD63_04685	COG0330	HflC and HflK could
FD63_04690	COG0330	HflC and HflK could
FD63_04700	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FD63_04725	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
FD63_04730	COG2801	Transposase and inactivated derivatives
FD63_04735	COG2963	transposase activity
FD63_04750	COG2801	Transposase and inactivated derivatives
FD63_04755	COG2963	transposase activity
FD63_04815	COG1063	alcohol dehydrogenase
FD63_04830	COG4106	trans-aconitate 2-methyltransferase activity
FD63_04840	COG0753	catalase activity
FD63_04850	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FD63_04850	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FD63_04875	COG2814	Major facilitator Superfamily
FD63_04895	COG2194	sulfuric ester hydrolase activity
FD63_04905	COG0745	RESPONSE REGULATOR receiver
FD63_04910	COG2205	protein histidine kinase activity
FD63_04925	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FD63_04930	COG2894	cell division
FD63_04935	COG0850	regulation of cytokinetic process
FD63_04945	COG4585	Histidine kinase
FD63_04965	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FD63_04975	COG1216	Glycosyl transferase, family 2
FD63_04980	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FD63_04990	COG1199	ATP-dependent helicase activity
FD63_05025	COG0189	ligase activity
FD63_05040	COG0835	chemotaxis
FD63_05045	COG0840	transmembrane signaling receptor activity
FD63_05055	COG2201	protein-glutamate methylesterase activity
FD63_05070	COG2963	transposase activity
FD63_05080	COG1446	asparaginase
FD63_05085	COG3142	Participates in the control of copper homeostasis
FD63_05125	COG0217	transcriptional regulatory protein
FD63_05135	COG0632	four-way junction helicase activity
FD63_05140	COG3158	transport of potassium into the cell
FD63_05150	COG0824	Thioesterase
FD63_05160	COG0848	biopolymer transport protein
FD63_05170	COG0823	Involved in the tonB-independent uptake of proteins
FD63_05175	COG2885	chlorophyll binding
FD63_05185	COG0602	queuosine metabolic process
FD63_05215	COG0514	ATP-dependent DNA helicase (RecQ)
FD63_05225	COG0783	Belongs to the Dps family
FD63_05230	COG1643	Atp-dependent helicase
FD63_05270	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FD63_05330	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
FD63_05345	COG1946	Acyl-CoA thioesterase
FD63_05360	COG0824	Thioesterase
FD63_05365	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FD63_05370	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FD63_05390	COG0728	peptidoglycan biosynthetic process
FD63_05405	COG0196	riboflavin kinase activity
FD63_05420	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FD63_05440	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FD63_05445	COG1845	cytochrome c oxidase, subunit III
FD63_05450	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FD63_05460	COG0156	8-amino-7-oxononanoate synthase activity
FD63_05470	COG3152	Membrane
FD63_05495	COG0745	RESPONSE REGULATOR receiver
FD63_05525	COG4794	Type iii secretion
FD63_05550	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FD63_05595	COG2207	Transcriptional regulator
FD63_05620	COG0129	dihydroxy-acid dehydratase activity
FD63_05640	COG1012	belongs to the aldehyde dehydrogenase family
FD63_05645	COG1879	ABC-type sugar transport system periplasmic component
FD63_05650	COG1129	ABC transporter
FD63_05655	COG1172	Belongs to the binding-protein-dependent transport system permease family
FD63_05660	COG1172	Belongs to the binding-protein-dependent transport system permease family
FD63_05670	COG1082	Xylose isomerase domain protein TIM barrel
FD63_05675	COG0625	glutathione transferase activity
FD63_05685	COG0475	glutathione-regulated potassium exporter activity
FD63_05710	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FD63_05715	COG2070	2-Nitropropane dioxygenase
FD63_05730	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FD63_05735	COG0336	Belongs to the RNA methyltransferase TrmD family
FD63_05740	COG0335	large ribosomal subunit rRNA binding
FD63_05745	COG0534	Mate efflux family protein
FD63_05775	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FD63_05790	COG2855	membrane
FD63_05825	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FD63_05835	COG0681	Belongs to the peptidase S26 family
FD63_05850	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FD63_05860	COG0745	RESPONSE REGULATOR receiver
FD63_05880	COG1472	Belongs to the glycosyl hydrolase 3 family
FD63_05890	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FD63_05895	COG1278	Cold shock
FD63_05900	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FD63_05910	COG1201	RNA secondary structure unwinding
FD63_05915	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FD63_05915	COG1793	dna ligase
FD63_05920	COG1793	dna ligase
FD63_05920	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FD63_05940	COG0745	RESPONSE REGULATOR receiver
FD63_05940	COG3706	GGDEF domain
FD63_05955	COG0443	Heat shock 70 kDa protein
FD63_05965	COG0183	Belongs to the thiolase family
FD63_05995	COG1703	isobutyryl-CoA mutase activity
FD63_05995	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FD63_05995	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FD63_06055	COG3250	beta-galactosidase activity
FD63_06060	COG2186	Transcriptional regulator
FD63_06070	COG0784	Response regulator, receiver
FD63_06070	COG2198	Histidine kinase
FD63_06070	COG2205	protein histidine kinase activity
FD63_06095	COG1451	nucleotide metabolic process
FD63_06110	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FD63_06145	COG1077	Cell shape determining protein MreB Mrl
FD63_06150	COG1047	Peptidyl-prolyl cis-trans
FD63_06155	COG2824	Alkylphosphonate utilization operon protein PhnA
FD63_06160	COG1902	pentaerythritol trinitrate reductase activity
FD63_06170	COG2814	Major facilitator Superfamily
FD63_06200	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FD63_06200	COG0392	lysyltransferase activity
FD63_06210	COG0251	oxidation-reduction process
FD63_06230	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FD63_06255	COG1595	DNA-templated transcription, initiation
FD63_06290	COG0346	lactoylglutathione lyase activity
FD63_06300	COG0833	amino acid
FD63_06305	COG2040	homocysteine
FD63_06315	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FD63_06330	COG3118	belongs to the thioredoxin family
FD63_06340	COG0495	leucyl-tRNA aminoacylation
FD63_06355	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FD63_06385	COG2968	Membrane
FD63_06395	COG1530	ribonuclease E activity
FD63_06405	COG0312	modulator of DNA gyrase
FD63_06415	COG0312	modulator of DNA gyrase
FD63_06490	COG3501	Rhs element vgr protein
FD63_06525	COG0631	protein serine/threonine phosphatase activity
FD63_06530	COG2815	serine threonine protein kinase
FD63_06530	COG0515	serine threonine protein kinase
FD63_06555	COG1858	cytochrome C peroxidase
FD63_06565	COG0142	geranyltranstransferase activity
FD63_06570	COG1722	exodeoxyribonuclease VII activity
FD63_06575	COG0037	tRNA processing
FD63_06585	COG1785	Belongs to the alkaline phosphatase family
FD63_06590	COG1301	dicarboxylic acid transport
FD63_06600	COG1607	acyl-coa hydrolase
FD63_06615	COG0791	NLP P60 protein
FD63_06620	COG0791	NLP P60 protein
FD63_06625	COG1047	Peptidyl-prolyl cis-trans
FD63_06630	COG2311	Membrane
FD63_06635	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FD63_06690	COG3590	peptidase
FD63_06705	COG0457	Tetratricopeptide repeat
FD63_06715	COG4771	TonB-dependent receptor
FD63_06725	COG2963	transposase activity
FD63_06730	COG4771	TonB-dependent receptor
FD63_06740	COG0489	protein tyrosine kinase activity
FD63_06745	COG0717	Belongs to the dCTP deaminase family
FD63_06750	COG1714	RDD family
FD63_06770	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FD63_06785	COG0494	nUDIX hydrolase
FD63_06790	COG0433	COG0433 Predicted ATPase
FD63_06795	COG0741	lytic transglycosylase activity
FD63_06800	COG0688	phosphatidylethanolamine metabolic process
FD63_06810	COG2890	protein-(glutamine-N5) methyltransferase activity
FD63_06825	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FD63_06875	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FD63_06900	COG1028	Short-chain dehydrogenase reductase Sdr
FD63_06905	COG0149	triose-phosphate isomerase activity
FD63_06920	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FD63_06930	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FD63_06940	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
FD63_06945	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FD63_06950	COG1034	ATP synthesis coupled electron transport
FD63_06970	COG0713	ATP synthesis coupled electron transport
FD63_06985	COG1007	ATP synthesis coupled electron transport
FD63_07000	COG0195	Participates in both transcription termination and antitermination
FD63_07025	COG1185	polyribonucleotide nucleotidyltransferase activity
FD63_07030	COG3300	MHYT domain
FD63_07030	COG5001	Diguanylate cyclase
FD63_07055	COG0840	transmembrane signaling receptor activity
FD63_07060	COG0840	transmembrane signaling receptor activity
FD63_07065	COG0835	chemotaxis
FD63_07110	COG1194	a g-specific adenine glycosylase
FD63_07115	COG0552	protein localization to endoplasmic reticulum
FD63_07125	COG3938	Belongs to the proline racemase family
FD63_07130	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FD63_07145	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FD63_07155	COG0006	proline dipeptidase activity
FD63_07170	COG0531	amino acid
FD63_07205	COG3507	Belongs to the glycosyl hydrolase 43 family
FD63_07215	COG4771	TonB-dependent receptor
FD63_07240	COG0742	ribosomal rna small subunit methyltransferase
FD63_07255	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FD63_07260	COG0405	Gamma-glutamyltransferase
FD63_07265	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FD63_07270	COG3291	Pkd domain containing protein
FD63_07275	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FD63_07285	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FD63_07295	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FD63_07305	COG1862	Preprotein translocase
FD63_07310	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FD63_07335	COG2203	Gaf domain
FD63_07335	COG3706	GGDEF domain
FD63_07335	COG4251	negative regulation of phosphorylation
FD63_07335	COG5001	Diguanylate cyclase
FD63_07340	COG1509	lysine 2,3-aminomutase activity
FD63_07350	COG3548	integral membrane protein
FD63_07355	COG0402	S-adenosylhomocysteine deaminase activity
FD63_07375	COG4677	pectinesterase activity
FD63_07395	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FD63_07405	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FD63_07465	COG2166	iron-sulfur cluster assembly
FD63_07480	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FD63_07485	COG0137	argininosuccinate synthase activity
FD63_07495	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FD63_07505	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FD63_07510	COG0165	Argininosuccinate lyase
FD63_07530	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FD63_07555	COG1070	Carbohydrate kinase
FD63_07560	COG2115	Belongs to the xylose isomerase family
FD63_07565	COG0477	Major facilitator Superfamily
FD63_07570	COG0860	N-Acetylmuramoyl-L-alanine amidase
FD63_07590	COG0617	tRNA 3'-terminal CCA addition
FD63_07600	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FD63_07615	COG0166	Belongs to the GPI family
FD63_07660	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
FD63_07675	COG0671	phosphoesterase, PA-phosphatase related
FD63_07695	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FD63_07700	COG0167	dihydroorotate dehydrogenase activity
FD63_07715	COG1012	belongs to the aldehyde dehydrogenase family
FD63_07735	COG0527	aspartate kinase activity
FD63_07735	COG0460	homoserine dehydrogenase
FD63_07740	COG0083	homoserine kinase activity
FD63_07745	COG2951	lytic endotransglycosylase activity
FD63_07755	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FD63_07765	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FD63_07770	COG0124	histidyl-tRNA synthetase
FD63_07780	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FD63_07785	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FD63_07800	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FD63_07815	COG0140	phosphoribosyl-ATP diphosphatase activity
FD63_07815	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FD63_07835	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
FD63_07840	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
FD63_07845	COG0235	Class ii aldolase
FD63_07850	COG0531	amino acid
FD63_07855	COG0531	amino acid
FD63_07870	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FD63_07875	COG0277	FAD linked oxidase domain protein
FD63_07895	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FD63_07915	COG1024	Enoyl-CoA hydratase
FD63_07950	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FD63_07955	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FD63_07960	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FD63_07965	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FD63_07975	COG0776	regulation of translation
FD63_08015	COG0438	transferase activity, transferring glycosyl groups
FD63_08020	COG0438	transferase activity, transferring glycosyl groups
FD63_08050	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FD63_08060	COG1960	acyl-CoA dehydrogenase activity
FD63_08125	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FD63_08125	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FD63_08130	COG0802	atpase or kinase
FD63_08135	COG0860	N-Acetylmuramoyl-L-alanine amidase
FD63_08140	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FD63_08160	COG1028	Short-chain dehydrogenase reductase Sdr
FD63_08180	COG2081	HI0933 family
FD63_08185	COG4681	YaeQ
FD63_08190	COG0564	pseudouridine synthase activity
FD63_08200	COG0625	glutathione transferase activity
FD63_08210	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FD63_08235	COG0513	Belongs to the DEAD box helicase family
FD63_08305	COG1846	Transcriptional regulator
FD63_08315	COG0386	Belongs to the glutathione peroxidase family
FD63_08340	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FD63_08390	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FD63_08395	COG0084	hydrolase, TatD family'
FD63_08410	COG1960	acyl-CoA dehydrogenase activity
FD63_08425	COG0305	Participates in initiation and elongation during chromosome replication
FD63_08430	COG0415	Belongs to the DNA photolyase family
FD63_08445	COG0583	DNA-binding transcription factor activity
FD63_08460	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FD63_08490	COG1404	Belongs to the peptidase S8 family
FD63_08495	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FD63_08500	COG2867	negative regulation of translational initiation
FD63_08510	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FD63_08515	COG0735	belongs to the Fur family
FD63_08520	COG0497	DNA recombination
FD63_08525	COG1420	regulation of RNA biosynthetic process
FD63_08530	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FD63_08535	COG0443	Heat shock 70 kDa protein
FD63_08540	COG0484	heat shock protein binding
FD63_08545	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
FD63_08550	COG0287	Prephenate dehydrogenase
FD63_08550	COG1605	Chorismate mutase
FD63_08560	COG1132	(ABC) transporter
FD63_08610	COG2850	peptidyl-arginine hydroxylation
FD63_08660	COG1131	(ABC) transporter
FD63_08665	COG1725	Transcriptional regulator
FD63_08675	COG0386	Belongs to the glutathione peroxidase family
FD63_08690	COG2900	Belongs to the SlyX family
FD63_08700	COG2755	lipolytic protein G-D-S-L family
FD63_08700	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FD63_08710	COG1410	methionine synthase
FD63_08710	COG0646	methionine synthase
FD63_08715	COG0646	methionine synthase
FD63_08715	COG1410	methionine synthase
FD63_08725	COG1960	acyl-CoA dehydrogenase activity
FD63_08740	COG2801	Transposase and inactivated derivatives
FD63_08760	COG2963	transposase activity
FD63_08765	COG2801	Transposase and inactivated derivatives
FD63_08775	COG2963	transposase activity
FD63_08815	COG0556	nucleotide-excision repair
FD63_08830	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FD63_08835	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FD63_08845	COG2902	Dehydrogenase
FD63_08850	COG2801	Transposase and inactivated derivatives
FD63_08855	COG2963	transposase activity
FD63_08880	COG1294	oxidase, subunit
FD63_08890	COG4988	ABC transporter
FD63_08895	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FD63_08900	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FD63_08945	COG4133	protoheme IX ABC transporter activity
FD63_08950	COG0436	Aminotransferase
FD63_08975	COG1187	pseudouridine synthase activity
FD63_08980	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FD63_08985	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FD63_08990	COG2350	Protein conserved in bacteria
FD63_09025	COG0395	ABC-type sugar transport system, permease component
FD63_09040	COG0129	dihydroxy-acid dehydratase activity
FD63_09055	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FD63_09070	COG2009	succinate dehydrogenase
FD63_09075	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
FD63_09090	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
FD63_09100	COG4591	ABC-type transport system involved in lipoprotein release permease component
FD63_09120	COG0811	peptide transport
FD63_09130	COG1132	(ABC) transporter
FD63_09145	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FD63_09160	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FD63_09200	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
FD63_09215	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FD63_09230	COG2963	transposase activity
FD63_09240	COG2963	transposase activity
FD63_09275	COG1132	(ABC) transporter
FD63_09305	COG1530	ribonuclease E activity
FD63_09320	COG0428	transporter
FD63_09335	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FD63_09335	COG0316	Belongs to the HesB IscA family
FD63_09355	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FD63_09375	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FD63_09380	COG2957	Belongs to the agmatine deiminase family
FD63_09390	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FD63_09395	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FD63_09400	COG0539	negative regulation of cytoplasmic translation
FD63_09405	COG0776	regulation of translation
FD63_09415	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
FD63_09420	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FD63_09430	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FD63_09435	COG0183	Belongs to the thiolase family
FD63_09440	COG1024	Enoyl-CoA hydratase
FD63_09440	COG1250	3-hydroxyacyl-CoA dehydrogenase
FD63_09450	COG0105	UTP biosynthetic process
FD63_09465	COG1426	Protein conserved in bacteria
FD63_09475	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FD63_09485	COG0746	molybdenum cofactor guanylyltransferase activity
FD63_09495	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FD63_09500	COG0475	glutathione-regulated potassium exporter activity
FD63_09500	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FD63_09515	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FD63_09525	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FD63_09525	COG0519	Catalyzes the synthesis of GMP from XMP
FD63_09530	COG1501	Belongs to the glycosyl hydrolase 31 family
FD63_09535	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
FD63_09545	COG1914	H( )-stimulated, divalent metal cation uptake system
FD63_09550	COG1321	iron dependent repressor
FD63_09555	COG0590	tRNA wobble adenosine to inosine editing
FD63_09560	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FD63_09565	COG0668	transmembrane transport
FD63_09575	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FD63_09590	COG1028	Short-chain dehydrogenase reductase Sdr
FD63_09595	COG1183	phosphatidylcholine synthase activity
FD63_09605	COG3243	poly(R)-hydroxyalkanoic acid synthase
FD63_09625	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FD63_09625	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FD63_09635	COG0784	Response regulator, receiver
FD63_09635	COG4191	Histidine kinase
FD63_09640	COG2183	response to ionizing radiation
FD63_09645	COG2205	protein histidine kinase activity
FD63_09645	COG0784	Response regulator, receiver
FD63_09680	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FD63_09730	COG1304	FMN binding
FD63_09795	COG1024	Enoyl-CoA hydratase
FD63_09800	COG1024	Enoyl-CoA hydratase
FD63_09810	COG1024	Enoyl-CoA hydratase
FD63_09825	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FD63_09830	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FD63_09850	COG2963	transposase activity
FD63_09855	COG2801	Transposase and inactivated derivatives
FD63_09865	COG1074	ATP-dependent DNA helicase activity
FD63_09905	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FD63_09910	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FD63_09920	COG0505	Belongs to the CarA family
FD63_09925	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FD63_09930	COG2258	MOSC domain
FD63_09935	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FD63_09940	COG2963	transposase activity
FD63_09945	COG2801	Transposase and inactivated derivatives
FD63_09955	COG0438	transferase activity, transferring glycosyl groups
FD63_09960	COG0438	transferase activity, transferring glycosyl groups
FD63_09980	COG4106	trans-aconitate 2-methyltransferase activity
FD63_10000	COG2244	polysaccharide biosynthetic process
FD63_10030	COG3038	cytochrome b561
FD63_10050	COG1595	DNA-templated transcription, initiation
FD63_10105	COG0038	chloride channel
FD63_10110	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FD63_10130	COG1674	ftsk spoiiie
FD63_10135	COG0492	ferredoxin-NADP+ reductase activity
FD63_10145	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FD63_10150	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FD63_10155	COG0542	response to heat
FD63_10175	COG0482	sulfurtransferase activity
FD63_10180	COG2915	High frequency lysogenization protein hflD homolog
FD63_10240	COG0784	Response regulator, receiver
FD63_10240	COG0835	chemotaxis
FD63_10250	COG1558	bacterial-type flagellum-dependent cell motility
FD63_10255	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FD63_10260	COG1749	Flagellar hook protein flgE
FD63_10270	COG4786	Flagellar basal body rod
FD63_10275	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
FD63_10290	COG1256	bacterial-type flagellum assembly
FD63_10290	COG4786	Flagellar basal body rod
FD63_10290	COG1256	bacterial-type flagellum assembly
FD63_10290	COG4786	Flagellar basal body rod
FD63_10300	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FD63_10305	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FD63_10325	COG2197	response regulator
FD63_10335	COG2201	protein-glutamate methylesterase activity
FD63_10340	COG2204	response regulator
FD63_10355	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FD63_10365	COG1028	Short-chain dehydrogenase reductase Sdr
FD63_10395	COG1677	Flagellar hook-basal body complex protein FliE
FD63_10445	COG3190	flagellar
FD63_10455	COG1987	bacterial-type flagellum assembly
FD63_10460	COG1684	flagellar biosynthetic protein fliR
FD63_10465	COG5001	Diguanylate cyclase
FD63_10465	COG3300	MHYT domain
FD63_10470	COG3706	GGDEF domain
FD63_10470	COG0745	RESPONSE REGULATOR receiver
FD63_10490	COG0455	bacterial-type flagellum organization
FD63_10505	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
FD63_10510	COG2198	Histidine kinase
FD63_10510	COG0643	Histidine kinase
FD63_10515	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FD63_10525	COG1192	Involved in chromosome partitioning
FD63_10530	COG0835	chemotaxis
FD63_10540	COG0745	RESPONSE REGULATOR receiver
FD63_10555	COG0840	transmembrane signaling receptor activity
FD63_10560	COG0840	transmembrane signaling receptor activity
FD63_10565	COG0840	transmembrane signaling receptor activity
FD63_10580	COG0840	transmembrane signaling receptor activity
FD63_10590	COG0840	transmembrane signaling receptor activity
FD63_10595	COG0840	transmembrane signaling receptor activity
FD63_10600	COG0840	transmembrane signaling receptor activity
FD63_10610	COG0840	transmembrane signaling receptor activity
FD63_10620	COG0835	chemotaxis
FD63_10630	COG0840	transmembrane signaling receptor activity
FD63_10640	COG0840	transmembrane signaling receptor activity
FD63_10655	COG2201	protein-glutamate methylesterase activity
FD63_10705	COG0318	PFAM AMP-dependent synthetase and ligase
FD63_10715	COG2198	Histidine kinase
FD63_10715	COG2205	protein histidine kinase activity
FD63_10715	COG0784	Response regulator, receiver
FD63_10730	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FD63_10750	COG0800	Aldolase
FD63_10765	COG3734	2-keto-3-deoxy-galactonokinase
FD63_10770	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FD63_10780	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FD63_10790	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FD63_10795	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FD63_10810	COG2201	protein-glutamate methylesterase activity
FD63_10830	COG0351	phosphomethylpyrimidine kinase
FD63_10830	COG0352	thiamine-phosphate diphosphorylase activity
FD63_10855	COG0583	DNA-binding transcription factor activity
FD63_10860	COG1741	Belongs to the pirin family
FD63_10885	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
FD63_10895	COG2137	regulation of response to DNA damage stimulus
FD63_10900	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FD63_10905	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FD63_10910	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FD63_10915	COG1546	Belongs to the CinA family
FD63_10920	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FD63_10925	COG1923	regulation of RNA biosynthetic process
FD63_10930	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FD63_10935	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FD63_10940	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FD63_10945	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FD63_10950	COG1534	Rna-binding protein
FD63_10965	COG1238	metal cluster binding
FD63_10975	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FD63_10990	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FD63_11045	COG0306	phosphate transporter
FD63_11055	COG1253	flavin adenine dinucleotide binding
FD63_11070	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FD63_11110	COG0069	glutamate synthase activity
FD63_11115	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FD63_11125	COG1609	Transcriptional regulator
FD63_11130	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FD63_11130	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FD63_11135	COG1105	Belongs to the carbohydrate kinase PfkB family
FD63_11140	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FD63_11140	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FD63_11150	COG0745	RESPONSE REGULATOR receiver
FD63_11175	COG1136	(ABC) transporter
FD63_11175	COG0577	efflux transmembrane transporter activity
FD63_11250	COG0583	DNA-binding transcription factor activity
FD63_11280	COG1605	Chorismate mutase
FD63_11280	COG0077	Prephenate dehydratase
FD63_11285	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FD63_11290	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FD63_11330	COG4221	oxidoreductase activity
FD63_11345	COG1228	amidohydrolase
FD63_11360	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FD63_11375	COG1309	transcriptional regulator
FD63_11395	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
FD63_11405	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
FD63_11410	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FD63_11415	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FD63_11430	COG0359	binds to the 23S rRNA
FD63_11450	COG0316	Belongs to the HesB IscA family
FD63_11475	COG2197	response regulator
FD63_11520	COG0288	reversible hydration of carbon dioxide
FD63_11535	COG3844	kynureninase activity
FD63_11545	COG2925	Exonuclease
FD63_11575	COG3039	Transposase
FD63_11585	COG2963	transposase activity
FD63_11590	COG2801	Transposase and inactivated derivatives
FD63_11630	COG3275	phosphorelay sensor kinase activity
FD63_11635	COG1611	Belongs to the LOG family
FD63_11645	COG2095	MarC family integral membrane protein
FD63_11650	COG1028	Short-chain dehydrogenase reductase Sdr
FD63_11655	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FD63_11695	COG2969	positive regulation of protein catabolic process
FD63_11700	COG0625	glutathione transferase activity
FD63_11705	COG2857	Cytochrome c1
FD63_11715	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FD63_11720	COG0723	plastoquinol--plastocyanin reductase activity
FD63_11740	COG1702	phosphate starvation-inducible protein PhoH
FD63_11755	COG4535	Mg2 and Co2 transporter CorC
FD63_11765	COG0598	Magnesium transport protein CorA
FD63_11770	COG1012	belongs to the aldehyde dehydrogenase family
FD63_11780	COG1177	transmembrane transport
FD63_11785	COG1176	ABC-type spermidine putrescine transport system, permease component I
FD63_11790	COG3842	ATPase activity
FD63_11825	COG0174	glutamine synthetase
FD63_11830	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FD63_11835	COG0174	glutamine synthetase
FD63_11840	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FD63_11845	COG0745	RESPONSE REGULATOR receiver
FD63_11845	COG3706	GGDEF domain
FD63_11850	COG0477	Major facilitator Superfamily
FD63_11865	COG0243	molybdopterin cofactor binding
FD63_11895	COG1012	belongs to the aldehyde dehydrogenase family
FD63_11900	COG1917	Cupin 2, conserved barrel domain protein
FD63_11900	COG1396	sequence-specific DNA binding
FD63_11910	COG0686	Belongs to the AlaDH PNT family
FD63_11930	COG2733	membrane
FD63_11935	COG0784	Response regulator, receiver
FD63_11935	COG5002	protein histidine kinase activity
FD63_11935	COG2205	protein histidine kinase activity
FD63_11995	COG1024	Enoyl-CoA hydratase
FD63_12005	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FD63_12030	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FD63_12035	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FD63_12040	COG0573	inorganic phosphate transmembrane transporter activity
FD63_12045	COG0581	inorganic phosphate transmembrane transporter activity
FD63_12055	COG0704	Plays a role in the regulation of phosphate uptake
FD63_12075	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FD63_12095	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FD63_12105	COG0557	exoribonuclease II activity
FD63_12140	COG2814	Major facilitator Superfamily
FD63_12145	COG1566	PFAM secretion protein HlyD family protein
FD63_12185	COG0367	asparagine synthase
FD63_12195	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FD63_12200	COG1393	Belongs to the ArsC family
FD63_12215	COG0024	Methionine aminopeptidase
FD63_12255	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FD63_12260	COG3706	GGDEF domain
FD63_12275	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FD63_12280	COG0575	Belongs to the CDS family
FD63_12285	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FD63_12290	COG0750	zinc metalloprotease
FD63_12300	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FD63_12310	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FD63_12315	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FD63_12415	COG2801	Transposase and inactivated derivatives
FD63_12420	COG2963	transposase activity
FD63_12430	COG1132	(ABC) transporter
FD63_12450	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FD63_12470	COG0745	RESPONSE REGULATOR receiver
FD63_12470	COG3706	GGDEF domain
FD63_12475	COG1187	pseudouridine synthase activity
FD63_12500	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FD63_12580	COG2080	2 iron, 2 sulfur cluster binding
FD63_12585	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
FD63_12590	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FD63_12635	COG0735	belongs to the Fur family
FD63_12670	COG2205	protein histidine kinase activity
FD63_12680	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FD63_12700	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FD63_12710	COG2198	Histidine kinase
FD63_12710	COG0643	Histidine kinase
FD63_12720	COG0840	transmembrane signaling receptor activity
FD63_12725	COG0840	transmembrane signaling receptor activity
FD63_12730	COG0835	chemotaxis
FD63_12765	COG2211	Major facilitator Superfamily
FD63_12795	COG1741	Belongs to the pirin family
FD63_12800	COG1966	Carbon starvation protein
FD63_12805	COG2879	small protein
FD63_12815	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FD63_12835	COG0823	Involved in the tonB-independent uptake of proteins
FD63_12835	COG1506	peptidase
FD63_12840	COG1297	OPT oligopeptide transporter protein
FD63_12845	COG3104	oligopeptide transport
FD63_12865	COG0629	single-stranded DNA binding
FD63_12870	COG0142	geranyltranstransferase activity
FD63_12895	COG0527	aspartate kinase activity
FD63_12900	COG0384	phenazine biosynthesis protein PhzF
FD63_12910	COG1764	response to oxidative stress
FD63_12925	COG0739	heme binding
FD63_12940	COG0693	protein deglycase activity
FD63_12955	COG0719	Fe-S assembly protein
FD63_12960	COG0396	ATPase activity
FD63_12965	COG0719	Fe-S assembly protein
FD63_12970	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FD63_12980	COG2146	nitrite reductase [NAD(P)H] activity
FD63_12985	COG4774	siderophore transport
FD63_13010	COG1477	protein flavinylation
FD63_13015	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FD63_13035	COG1555	photosystem II stabilization
FD63_13050	COG3178	'Phosphotransferase
FD63_13055	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FD63_13065	COG0628	permease
FD63_13090	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FD63_13130	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FD63_13145	COG1137	ATPase activity
FD63_13160	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FD63_13170	COG1660	Displays ATPase and GTPase activities
FD63_13180	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FD63_13185	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FD63_13190	COG2239	Acts as a magnesium transporter
FD63_13210	COG1113	amino acid transport
FD63_13220	COG0840	transmembrane signaling receptor activity
FD63_13245	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FD63_13260	COG0519	Catalyzes the synthesis of GMP from XMP
FD63_13275	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FD63_13315	COG0259	pyridoxamine-phosphate oxidase activity
FD63_13320	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FD63_13340	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FD63_13350	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FD63_13355	COG2814	Major facilitator Superfamily
FD63_13375	COG3038	cytochrome b561
FD63_13390	COG1760	l-serine dehydratase
FD63_13395	COG3706	GGDEF domain
FD63_13405	COG0460	homoserine dehydrogenase
FD63_13405	COG0527	aspartate kinase activity
FD63_13410	COG0626	cystathionine gamma-synthase activity
FD63_13415	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FD63_13425	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FD63_13430	COG1272	protein, Hemolysin III
FD63_13435	COG2982	Protein involved in outer membrane biogenesis
FD63_13440	COG0517	IMP dehydrogenase activity
FD63_13445	COG0463	Glycosyl transferase, family 2
FD63_13450	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FD63_13455	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FD63_13470	COG2963	transposase activity
FD63_13475	COG2801	Transposase and inactivated derivatives
FD63_13500	COG1304	FMN binding
FD63_13510	COG1657	PFAM Prenyltransferase squalene oxidase
FD63_13515	COG0142	geranyltranstransferase activity
FD63_13520	COG2124	cytochrome p450
FD63_13525	COG1028	Short-chain dehydrogenase reductase Sdr
FD63_13530	COG1141	Ferredoxin
FD63_13535	COG2124	cytochrome p450
FD63_13540	COG2124	cytochrome p450
FD63_13605	COG0330	HflC and HflK could
FD63_13615	COG1742	UPF0060 membrane protein
FD63_13620	COG3956	TIGRFAM MazG family protein
FD63_13625	COG1218	3'(2'),5'-bisphosphate nucleotidase
FD63_13630	COG0494	nUDIX hydrolase
FD63_13640	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FD63_13650	COG0837	glucose binding
FD63_13665	COG1388	LysM domain
FD63_13665	COG3858	chitin binding
FD63_13670	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FD63_13680	COG1472	Belongs to the glycosyl hydrolase 3 family
FD63_13700	COG3537	Alpha-1,2-mannosidase
FD63_13740	COG2963	transposase activity
FD63_13775	COG3501	Rhs element vgr protein
FD63_13855	COG2963	transposase activity
FD63_14010	COG3501	Rhs element vgr protein
FD63_14085	COG0521	Mo-molybdopterin cofactor biosynthetic process
FD63_14115	COG1295	ribonuclease BN
FD63_14135	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FD63_14145	COG1404	Belongs to the peptidase S8 family
FD63_14150	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FD63_14165	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FD63_14170	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
FD63_14190	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
FD63_14210	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FD63_14210	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FD63_14245	COG2963	transposase activity
FD63_14250	COG2801	Transposase and inactivated derivatives
FD63_14255	COG2963	transposase activity
FD63_14260	COG2801	Transposase and inactivated derivatives
FD63_14290	COG4651	solute:proton antiporter activity
FD63_14290	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FD63_14305	COG4772	TonB-dependent receptor
FD63_14315	COG4264	IucA IucC family
FD63_14320	COG2814	Major facilitator Superfamily
FD63_14325	COG4264	IucA IucC family
FD63_14330	COG0019	diaminopimelate decarboxylase activity
FD63_14360	COG0542	response to heat
FD63_14415	COG3387	PFAM Glycoside hydrolase 15-related
FD63_14425	COG4993	Dehydrogenase
FD63_14445	COG0840	transmembrane signaling receptor activity
FD63_14460	COG0564	pseudouridine synthase activity
FD63_14465	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FD63_14475	COG1125	glycine betaine transport
FD63_14480	COG1174	glycine betaine transport
FD63_14495	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FD63_14505	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FD63_14505	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FD63_14560	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
FD63_14575	COG0745	RESPONSE REGULATOR receiver
FD63_14585	COG0189	ligase activity
FD63_14595	COG3511	phospholipase C
FD63_14620	COG0626	cystathionine gamma-synthase activity
FD63_14650	COG2022	thiamine diphosphate biosynthetic process
FD63_14660	COG0471	metal ion transport
FD63_14660	COG3273	potassium ion transport
FD63_14675	COG0179	Fumarylacetoacetate (FAA) hydrolase
FD63_14690	COG1609	Transcriptional regulator
FD63_14705	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FD63_14715	COG1115	amino acid carrier protein
FD63_14735	COG0840	transmembrane signaling receptor activity
FD63_14740	COG0529	Catalyzes the synthesis of activated sulfate
FD63_14740	COG2895	sulfate adenylyltransferase (ATP) activity
FD63_14750	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FD63_14755	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FD63_14760	COG0175	sulfate reduction
FD63_14790	COG1393	Belongs to the ArsC family
FD63_14795	COG0784	Response regulator, receiver
FD63_14795	COG2198	Histidine kinase
FD63_14795	COG2205	protein histidine kinase activity
FD63_14810	COG1648	precorrin-2 dehydrogenase activity
FD63_14810	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FD63_14825	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FD63_14850	COG1957	nucleoside hydrolase
FD63_14870	COG3588	fructose-bisphosphate aldolase
FD63_14875	COG0469	pyruvate kinase activity
FD63_14920	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FD63_14925	COG3047	cAMP biosynthetic process
FD63_14945	COG0640	Transcriptional regulator
FD63_14955	COG0725	ABC transporter, periplasmic molybdate-binding protein
FD63_14960	COG4149	molybdate abc transporter
FD63_14965	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FD63_14990	COG1376	ErfK ybiS ycfS ynhG family protein
FD63_14995	COG0739	heme binding
FD63_15020	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FD63_15025	COG1301	dicarboxylic acid transport
FD63_15055	COG0714	Associated with various cellular activities
FD63_15100	COG0006	proline dipeptidase activity
FD63_15105	COG0006	proline dipeptidase activity
FD63_15110	COG3079	Belongs to the UPF0149 family
FD63_15130	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FD63_15140	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FD63_15155	COG1773	rubredoxin
FD63_15185	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FD63_15200	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
FD63_15210	COG2010	Cytochrome c
FD63_15220	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FD63_15230	COG1940	carbohydrate kinase activity
FD63_15245	COG0671	phosphoesterase, PA-phosphatase related
FD63_15255	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FD63_15285	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
FD63_15295	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FD63_15315	COG0840	transmembrane signaling receptor activity
FD63_15320	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FD63_15340	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FD63_15350	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FD63_15360	COG0066	3-isopropylmalate dehydratase activity
FD63_15365	COG0473	3-isopropylmalate dehydrogenase activity
FD63_15370	COG3706	GGDEF domain
FD63_15380	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FD63_15385	COG1538	Outer membrane efflux protein
FD63_15390	COG1519	Transferase
FD63_15395	COG1560	Kdo2-lipid A biosynthetic process
FD63_15440	COG0281	malic enzyme
FD63_15440	COG0280	phosphate acetyltransferase
FD63_15445	COG1301	dicarboxylic acid transport
FD63_15455	COG4191	Histidine kinase
FD63_15470	COG1840	ABC-type Fe3 transport system, periplasmic component
FD63_15475	COG0642	Histidine kinase
FD63_15490	COG2851	Citrate transporter
FD63_15495	COG1028	Short-chain dehydrogenase reductase Sdr
FD63_15505	COG2211	Major facilitator Superfamily
FD63_15535	COG1162	GTPase activity
FD63_15540	COG0436	Aminotransferase
FD63_15565	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FD63_15585	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FD63_15635	COG3791	Glutathione-dependent formaldehyde-activating
FD63_15640	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FD63_15650	COG0745	RESPONSE REGULATOR receiver
FD63_15655	COG2205	protein histidine kinase activity
FD63_15725	COG0617	tRNA 3'-terminal CCA addition
FD63_15735	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FD63_15740	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FD63_15745	COG1609	Transcriptional regulator
FD63_15750	COG0738	Major facilitator superfamily
FD63_15755	COG2188	Transcriptional regulator
FD63_15770	COG3250	beta-galactosidase activity
FD63_15805	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FD63_15815	COG4191	Histidine kinase
FD63_15820	COG0784	Response regulator, receiver
FD63_15825	COG2205	protein histidine kinase activity
FD63_15825	COG2202	Pas domain
FD63_15835	COG2823	Periplasmic or secreted lipoprotein
FD63_15840	COG0673	inositol 2-dehydrogenase activity
FD63_15845	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FD63_15855	COG1090	epimerase
FD63_15875	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FD63_15915	COG2226	methyltransferase
FD63_15940	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FD63_15950	COG0494	nUDIX hydrolase
FD63_15965	COG0739	heme binding
FD63_15975	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
FD63_15980	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FD63_15990	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FD63_15995	COG1181	Belongs to the D-alanine--D-alanine ligase family
FD63_16020	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FD63_16035	COG3116	cell division
FD63_16040	COG0275	rRNA processing
FD63_16045	COG2001	Belongs to the MraZ family
FD63_16075	COG1988	membrane-bound metal-dependent
FD63_16080	COG0277	FAD linked oxidase domain protein
FD63_16085	COG0745	RESPONSE REGULATOR receiver
FD63_16090	COG2205	protein histidine kinase activity
FD63_16100	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FD63_16105	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FD63_16130	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FD63_16135	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FD63_16140	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FD63_16155	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FD63_16155	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FD63_16165	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FD63_16195	COG0477	Major facilitator Superfamily
FD63_16200	COG0488	(ABC) transporter
FD63_16205	COG0242	peptide deformylase activity
FD63_16225	COG1215	transferase activity, transferring glycosyl groups
FD63_16235	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FD63_16240	COG0457	Tetratricopeptide repeat
FD63_16290	COG2188	Transcriptional regulator
FD63_16300	COG1450	Type ii and iii secretion system protein
FD63_16315	COG3166	PFAM Fimbrial assembly family protein
FD63_16320	COG3156	type II secretion system protein K
FD63_16325	COG4795	General secretion pathway protein
FD63_16330	COG2165	general secretion pathway protein
FD63_16335	COG4970	Tfp pilus assembly protein FimT
FD63_16340	COG2165	general secretion pathway protein
FD63_16345	COG1459	type II secretion system
FD63_16350	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FD63_16355	COG1404	Belongs to the peptidase S8 family
FD63_16375	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FD63_16375	COG0047	phosphoribosylformylglycinamidine synthase activity
FD63_16380	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FD63_16385	COG4974	Belongs to the 'phage' integrase family
FD63_16410	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FD63_16415	COG2927	DNA polymerase III (CHI subunit)
FD63_16450	COG1183	phosphatidylcholine synthase activity
FD63_16475	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FD63_16480	COG1127	ABC transporter
FD63_16485	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FD63_16485	COG3218	ABC-type transport auxiliary lipoprotein component
FD63_16515	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FD63_16520	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FD63_16525	COG0662	Cupin 2, conserved barrel domain protein
FD63_16525	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
FD63_16550	COG2086	electron transfer activity
FD63_16565	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FD63_16565	COG0546	phosphoglycolate phosphatase activity
FD63_16570	COG0277	FAD linked oxidase domain protein
FD63_16575	COG0300	oxidoreductase activity
FD63_16600	COG0493	'glutamate synthase
FD63_16620	COG0438	transferase activity, transferring glycosyl groups
FD63_16620	COG1216	Glycosyl transferase, family 2
FD63_16645	COG0438	transferase activity, transferring glycosyl groups
FD63_16645	COG1216	Glycosyl transferase, family 2
FD63_16650	COG1216	Glycosyl transferase, family 2
FD63_16650	COG0438	transferase activity, transferring glycosyl groups
FD63_16655	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FD63_16670	COG0626	cystathionine gamma-synthase activity
FD63_16700	COG0625	glutathione transferase activity
FD63_16710	COG0513	Belongs to the DEAD box helicase family
FD63_16715	COG0720	synthase
FD63_16730	COG1956	GAF domain-containing protein
FD63_16740	COG4206	TonB-dependent receptor
FD63_16745	COG0546	phosphoglycolate phosphatase activity
FD63_16750	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FD63_16755	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FD63_16775	COG0339	signal peptide processing
FD63_16790	COG2217	Heavy metal translocating P-type atpase
FD63_16805	COG2132	Multicopper oxidase
FD63_16820	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FD63_16830	COG1136	(ABC) transporter
FD63_16835	COG1136	(ABC) transporter
FD63_16835	COG0577	efflux transmembrane transporter activity
FD63_16840	COG1136	(ABC) transporter
FD63_16840	COG0577	efflux transmembrane transporter activity
FD63_16845	COG1136	(ABC) transporter
FD63_16845	COG0577	efflux transmembrane transporter activity
FD63_16860	COG2204	response regulator
FD63_16865	COG4191	Histidine kinase
FD63_16875	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FD63_16890	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FD63_16905	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FD63_16915	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FD63_16925	COG0356	it plays a direct role in the translocation of protons across the membrane
FD63_16940	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FD63_16945	COG0508	dehydrogenase complex catalyzes the overall conversion of
FD63_16980	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FD63_16985	COG0697	spore germination
FD63_16990	COG1666	GTP binding
FD63_17000	COG1187	pseudouridine synthase activity
FD63_17025	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FD63_17025	COG2205	protein histidine kinase activity
FD63_17055	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FD63_17060	COG1522	sequence-specific DNA binding
FD63_17125	COG0842	Transport permease protein
FD63_17130	COG1131	(ABC) transporter
FD63_17135	COG0025	NhaP-type Na H and K H
FD63_17145	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
FD63_17150	COG1573	uracil-dna glycosylase
FD63_17160	COG3384	dioxygenase
FD63_17185	COG0667	Aldo Keto reductase
FD63_17195	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FD63_17200	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FD63_17220	COG3706	GGDEF domain
FD63_17230	COG5001	Diguanylate cyclase
FD63_17260	COG4106	trans-aconitate 2-methyltransferase activity
FD63_17270	COG2076	Multidrug Resistance protein
FD63_17280	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FD63_17300	COG3279	Response regulator of the LytR AlgR family
FD63_17330	COG0531	amino acid
FD63_17340	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
FD63_17340	COG5297	Belongs to the glycosyl hydrolase family 6
FD63_17360	COG0741	lytic transglycosylase activity
FD63_17380	COG2207	Transcriptional regulator
FD63_17395	COG0598	Magnesium transport protein CorA
FD63_17400	COG1113	amino acid transport
FD63_17405	COG0697	spore germination
FD63_17430	COG5520	Belongs to the glycosyl hydrolase 30 family
FD63_17500	COG0840	transmembrane signaling receptor activity
FD63_17515	COG2353	YceI-like domain
FD63_17540	COG0584	glycerophosphoryl diester phosphodiesterase
FD63_17575	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FD63_17585	COG4771	TonB-dependent receptor
FD63_17610	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FD63_17615	COG0459	protein refolding
FD63_17620	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FD63_17625	COG1324	tolerance protein
FD63_17635	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FD63_17650	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FD63_17655	COG0511	ligase activity, forming carbon-carbon bonds
FD63_17660	COG0439	Biotin carboxylase
FD63_17680	COG2264	protein methyltransferase activity
FD63_17700	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FD63_17710	COG4589	Belongs to the CDS family
FD63_17730	COG2267	carboxylic ester hydrolase activity
FD63_17745	COG0138	bifunctional purine biosynthesis protein purh
FD63_17750	COG0151	Belongs to the GarS family
FD63_17765	COG1289	transmembrane transporter activity
FD63_17810	COG2816	NAD+ diphosphatase activity
FD63_17850	COG2906	2 iron, 2 sulfur cluster binding
FD63_17875	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FD63_17880	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
FD63_17895	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
FD63_17900	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FD63_17905	COG0730	response to heat
FD63_17920	COG0134	indole-3-glycerol-phosphate synthase activity
FD63_17925	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FD63_17950	COG1597	lipid kinase activity
FD63_17965	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FD63_17980	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FD63_17985	COG2111	Na H antiporter
FD63_17985	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FD63_17990	COG1006	Multisubunit Na H antiporter MnhC subunit
FD63_17995	COG0651	ATP synthesis coupled electron transport
FD63_18000	COG1863	multisubunit Na H antiporter MnhE subunit
FD63_18005	COG2212	antiporter activity
FD63_18010	COG1320	monovalent cation:proton antiporter activity
FD63_18015	COG0530	calcium, potassium:sodium antiporter activity
FD63_18050	COG3104	oligopeptide transport
FD63_18055	COG3483	tryptophan 2,3-dioxygenase activity
FD63_18070	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FD63_18085	COG0508	dehydrogenase complex catalyzes the overall conversion of
FD63_18115	COG0513	Belongs to the DEAD box helicase family
FD63_18130	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FD63_18135	COG3706	GGDEF domain
FD63_18140	COG2354	Protein conserved in bacteria
FD63_18160	COG1196	nuclear chromosome segregation
FD63_18160	COG3264	Mechanosensitive ion channel
FD63_18165	COG0604	alcohol dehydrogenase
FD63_18165	COG3321	synthase
FD63_18165	COG1028	Short-chain dehydrogenase reductase Sdr
FD63_18185	COG1595	DNA-templated transcription, initiation
FD63_18200	COG1802	Transcriptional regulator
FD63_18215	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
FD63_18235	COG3052	prosthetic group binding
FD63_18245	COG1414	Transcriptional regulator
FD63_18250	COG0738	Major facilitator superfamily
FD63_18255	COG3254	rhamnose metabolic process
FD63_18260	COG4948	Mandelate Racemase Muconate Lactonizing
FD63_18265	COG0179	Fumarylacetoacetate (FAA) hydrolase
FD63_18270	COG1028	Short-chain dehydrogenase reductase Sdr
FD63_18305	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FD63_18320	COG4807	Protein conserved in bacteria
FD63_18365	COG1506	peptidase
FD63_18365	COG0823	Involved in the tonB-independent uptake of proteins
FD63_18425	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FD63_18445	COG0628	permease
FD63_18450	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FD63_18455	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FD63_18465	COG0753	catalase activity
FD63_18490	COG1136	(ABC) transporter
FD63_18495	COG0577	efflux transmembrane transporter activity
FD63_18515	COG0697	spore germination
FD63_18530	COG0180	Tryptophanyl-tRNA synthetase
FD63_18565	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
FD63_18570	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
FD63_18570	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
FD63_18580	COG3228	Belongs to the MtfA family
FD63_18595	COG2205	protein histidine kinase activity
FD63_18600	COG0745	RESPONSE REGULATOR receiver
FD63_18610	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FD63_18645	COG2084	Dehydrogenase
FD63_18650	COG1902	pentaerythritol trinitrate reductase activity
FD63_18675	COG1404	Belongs to the peptidase S8 family
FD63_18680	COG2814	Major facilitator Superfamily
FD63_18685	COG0583	DNA-binding transcription factor activity
FD63_18695	COG2801	Transposase and inactivated derivatives
FD63_18700	COG2963	transposase activity
FD63_18720	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FD63_18725	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FD63_18735	COG1764	response to oxidative stress
FD63_18740	COG1846	Transcriptional regulator
FD63_18745	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FD63_18755	COG0697	spore germination
FD63_18765	COG0523	cobalamin synthesis protein
FD63_18775	COG1742	UPF0060 membrane protein
FD63_18780	COG3245	cytochrome
FD63_18790	COG1960	acyl-CoA dehydrogenase activity
FD63_18795	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FD63_18825	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FD63_18830	COG3387	PFAM Glycoside hydrolase 15-related
FD63_18840	COG0745	RESPONSE REGULATOR receiver
FD63_18855	COG1404	Belongs to the peptidase S8 family
FD63_18865	COG3100	YcgL domain-containing protein
FD63_18870	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FD63_18880	COG0463	Glycosyl transferase, family 2
FD63_18890	COG1028	Short-chain dehydrogenase reductase Sdr
FD63_18915	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FD63_18930	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FD63_18955	COG1294	oxidase, subunit
FD63_18960	COG1271	oxidase subunit
FD63_18975	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FD63_18980	COG0408	coproporphyrinogen oxidase activity
FD63_18990	COG2323	membrane
FD63_18995	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FD63_18995	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FD63_19010	COG0589	response to stress
FD63_19030	COG0210	DNA helicase
FD63_19045	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FD63_19050	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FD63_19075	COG0463	Glycosyl transferase, family 2
FD63_19085	COG1475	DNA binding
FD63_19090	COG1192	Involved in chromosome partitioning
FD63_19095	COG0357	Ribosomal RNA small subunit methyltransferase G
FD63_19115	COG2091	lysine biosynthetic process via aminoadipic acid
FD63_19150	COG0477	Major facilitator Superfamily
FD63_19170	COG1971	Probably functions as a manganese efflux pump
FD63_19180	COG2205	protein histidine kinase activity
FD63_19195	COG3459	Glycosyltransferase 36 associated
FD63_19200	COG2211	Major facilitator Superfamily
FD63_19205	COG3265	gluconokinase activity
FD63_19225	COG2911	Protein conserved in bacteria
FD63_19230	COG0729	surface antigen
FD63_19250	COG3132	Protein of unknown function, DUF480
FD63_19270	COG2963	transposase activity
FD63_19275	COG2963	transposase activity
FD63_19280	COG2801	Transposase and inactivated derivatives
FD63_19305	COG0284	orotidine-5'-phosphate decarboxylase activity
FD63_19330	COG2937	Belongs to the GPAT DAPAT family
FD63_19360	COG2211	Major facilitator Superfamily
FD63_19370	COG3693	PFAM glycoside hydrolase, family 10
FD63_19390	COG3386	PFAM SMP-30 Gluconolaconase
FD63_19400	COG2963	transposase activity
FD63_19410	COG3046	protein related to deoxyribodipyrimidine photolyase
FD63_19425	COG0246	Mannitol dehydrogenase
FD63_19440	COG4948	Mandelate Racemase Muconate Lactonizing
FD63_19450	COG3661	Belongs to the glycosyl hydrolase 67 family
FD63_19460	COG2115	Belongs to the xylose isomerase family
FD63_19465	COG0037	tRNA processing
FD63_19490	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FD63_19500	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FD63_19510	COG0805	protein transport
FD63_19520	COG0519	Catalyzes the synthesis of GMP from XMP
FD63_19520	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FD63_19525	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FD63_19530	COG0752	glycyl-tRNA synthetase alpha subunit
FD63_19545	COG0210	DNA helicase
FD63_19550	COG1435	thymidine kinase activity
FD63_19565	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
FD63_19575	COG0515	serine threonine protein kinase
FD63_19575	COG0457	Tetratricopeptide repeat
FD63_19590	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FD63_19605	COG1119	ATPase activity
FD63_19620	COG0706	membrane insertase activity
FD63_19625	COG0594	ribonuclease P activity
FD63_19630	COG0230	Belongs to the bacterial ribosomal protein bL34 family