locus-tag	class	description
NX81_000010	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
NX81_000015	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
NX81_000025	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
NX81_000035	ENOG4108K0D	peptidase, M48
NX81_000065	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
NX81_000075	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
NX81_000105	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
NX81_000120	ENOG4105C5I	Dehydrogenase
NX81_000125	ENOG4105CN1	protease
NX81_000130	ENOG41063SB	peptidase
NX81_000140	ENOG4107VAM	peptidase, m28
NX81_000170	ENOG4105DQ4	alcohol dehydrogenase
NX81_000185	ENOG4105BZ8	glutamate synthase
NX81_000190	ENOG4105CBC	glutamate synthase
NX81_000275	ENOG4108I5C	dEAD DEAH box helicase
NX81_000280	ENOG4108UT2	hemolysin iii
NX81_000320	ENOG4105D4Y	metalloprotease
NX81_000325	ENOG4105E09	nadh pyrophosphatase
NX81_000340	ENOG4105K63	Thioredoxin
NX81_000350	ENOG4105CSH	Transporter
NX81_000390	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
NX81_000405	ENOG4105CGF	Aromatic amino acid aminotransferase
NX81_000410	ENOG4105CHB	tonB-dependent Receptor
NX81_000435	ENOG4105DMF	Dehydrogenase
NX81_000455	ENOG4105BZU	Histidine kinase
NX81_000460	ENOG4105WH1	Two component transcriptional regulator luxr family
NX81_000480	ENOG4105RKW	reductase (By
NX81_000530	ENOG4105F2I	Transposase
NX81_000540	ENOG4105D5K	Hemolysin activator protein
NX81_000550	ENOG4105EP6	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity)
NX81_000555	ENOG4105CG3	alpha amylase, catalytic region
NX81_000575	ENOG4105EBR	Carboxylesterase
NX81_000590	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
NX81_000600	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
NX81_000605	ENOG4105DSG	hydrolase family 43
NX81_000610	ENOG4105ETE	Transcriptional regulator (LacI family
NX81_000615	ENOG4105D50	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate (By similarity)
NX81_000620	ENOG4105CHR	reductase
NX81_000630	ENOG4107TDE	lipolytic protein G-D-S-L family
NX81_000640	ENOG4105MIR	Phenylalanine 4-monooxygenase
NX81_000645	ENOG4108YXU	transcriptional regulator AsnC family
NX81_000650	ENOG4105CNM	Receptor
NX81_000660	ENOG4105CVE	Lytic murein transglycosylase
NX81_000665	ENOG4105D78	K07001 NTE family protein
NX81_000670	ENOG4105CH2	amidohydrolase
NX81_000680	ENOG4105DKW	ABC transporter
NX81_000695	ENOG4108IJ8	ABC transporter
NX81_000700	ENOG4105E90	ABC transporter
NX81_000740	ENOG4105D1F	ATP-binding protein
NX81_000745	ENOG4105M4E	phosphohistidine phosphatase, SixA
NX81_000755	ENOG4107RZC	phospholipase d
NX81_000760	ENOG4105KA0	thioesterase Superfamily protein
NX81_000810	ENOG4105C5F	glutamine synthetase
NX81_000820	ENOG4105BZU	Histidine kinase
NX81_000825	ENOG4105CUX	Signal transduction histidine kinase
NX81_000830	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
NX81_000835	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
NX81_000840	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
NX81_000850	ENOG4105I9P	Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity)
NX81_000860	ENOG4105CHU	acetyl-coa acetyltransferase
NX81_000900	ENOG4107YZP	Rhodanese domain protein
NX81_000905	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
NX81_000910	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
NX81_000920	ENOG4105C7K	acetolactate synthase
NX81_000925	ENOG4108TQ9	Histidine kinase
NX81_000930	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
NX81_000950	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
NX81_000965	ENOG4105E2T	synthase III
NX81_000970	ENOG4107R3N	Filamentation induced by cAMP protein fic
NX81_000985	ENOG4108J2P	Alpha beta hydrolase fold
NX81_000990	ENOG4105PI0	Ferredoxin
NX81_000995	ENOG410680H	amp-dependent synthetase and ligase
NX81_001000	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
NX81_001020	ENOG4105CPF	Cell wall formation (By similarity)
NX81_001040	ENOG4105DR9	pseudouridine synthase
NX81_001050	ENOG4108YZN	class I peptide chain release factor
NX81_001065	ENOG4105DGW	oligopeptidase A
NX81_001105	ENOG4107R11	Transcriptional regulator
NX81_001110	ENOG4107QP3	malate synthase g
NX81_001120	ENOG4105BZU	Histidine kinase
NX81_001150	ENOG4107QX3	carboxylase
NX81_001155	ENOG4105C1G	acyl-Coa dehydrogenase
NX81_001210	ENOG4105CKI	cobalamin synthesis protein
NX81_001220	ENOG4108TZV	Membrane
NX81_001230	ENOG4105D6Z	AFG1 family ATPase
NX81_001240	ENOG4105K56	Transcriptional regulator
NX81_001245	ENOG4108ZHJ	Organic hydroperoxide resistance protein
NX81_001265	ENOG4105CV8	reductase
NX81_001270	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
NX81_001285	ENOG4108R99	pseudouridine synthase
NX81_001295	ENOG4105CQ7	ATP-dependent helicase
NX81_001300	ENOG4108W15	Protein of unknown function (DUF1456)
NX81_001305	ENOG4105VT2	5-hydroxyisourate hydrolase
NX81_001310	ENOG4105E1J	oxidoreductase
NX81_001330	ENOG4105C5R	Aminotransferase
NX81_001355	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
NX81_001375	ENOG4105C7N	Xanthine uracil vitamin C permease
NX81_001390	ENOG4105ETT	transcriptional Regulator, LysR family
NX81_001395	ENOG4105F8V	Hydrolase, tatD family
NX81_001430	ENOG4106NZI	LysR family Transcriptional regulator
NX81_001440	ENOG4105EMU	Dehydrogenase
NX81_001450	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
NX81_001455	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
NX81_001480	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
NX81_001500	ENOG4105WPN	DNA integration recombination invertion protein
NX81_001505	ENOG4105DZ2	Transcriptional regulator
NX81_001510	ENOG4108UZX	fmn reductase
NX81_001540	ENOG4105ECR	NmrA family
NX81_001595	ENOG4105F2I	Transposase
NX81_001620	ENOG4105C01	Dihydroxy-acid dehydratase
NX81_001635	ENOG4108Z0R	Transferase
NX81_001645	ENOG4105D2S	major facilitator superfamily
NX81_001650	ENOG4105CPI	Metal Dependent Phosphohydrolase
NX81_001680	ENOG41072AC	4-hydroxybenzoate 3-monooxygenase
NX81_001690	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
NX81_001695	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
NX81_001700	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
NX81_001710	ENOG4105E98	transcriptional regulator DeoR family
NX81_001735	ENOG4105CHU	acetyl-coa acetyltransferase
NX81_001755	ENOG4107RAW	3-carboxy-cis-cis-muconate cycloisomerase
NX81_001760	ENOG4105F2Z	3-oxoadipate enol-lactonase
NX81_001765	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
NX81_001770	ENOG4107HP6	Transcriptional regulator
NX81_001785	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
NX81_001830	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
NX81_001845	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
NX81_001850	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
NX81_001855	ENOG41081UC	Inherit from COG: Competence protein
NX81_001890	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
NX81_001960	ENOG4105VS8	Flagellar biosynthetic protein fliq
NX81_001980	ENOG4108HR8	type iii secretion
NX81_002000	ENOG4107Y59	type iii secretion
NX81_002015	ENOG4108JIR	Flagellum-specific ATP synthase
NX81_002030	ENOG4105K44	type iii secretion
NX81_002040	ENOG4105FTC	Lytic transglycosylase catalytic
NX81_002055	ENOG4105EGS	Mechanosensitive ion channel
NX81_002060	ENOG4107RES	phosphoglycerol transferase I
NX81_002075	ENOG4105CKW	Inner membrane protein yedI
NX81_002080	ENOG4105F32	YngK protein
NX81_002085	ENOG4105BZU	Histidine kinase
NX81_002090	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
NX81_002095	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
NX81_002100	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
NX81_002125	ENOG4105K4T	epimerase
NX81_002130	ENOG41090TK	Short-chain dehydrogenase reductase Sdr
NX81_002155	ENOG4105C1J	atp-dependent rna helicase
NX81_002170	ENOG4105C7S	Dehydrogenase
NX81_002185	ENOG4107RUY	(E1 component), alpha subunit
NX81_002205	ENOG4105DUX	Transporter
NX81_002220	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
NX81_002225	ENOG4105F1J	Homogentisate 1,2-dioxygenase
NX81_002265	ENOG4105KJM	monovalent cation h antiporter subunit g
NX81_002270	ENOG4105W4C	monovalent cation H antiporter subunit F
NX81_002280	ENOG4107R4Z	monovalent cation h antiporter subunit d
NX81_002285	ENOG4108ZE9	Monovalent cation H antiporter subunit C
NX81_002290	ENOG4105D65	subunit l
NX81_002340	ENOG4105C8V	SAICAR synthetase
NX81_002345	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
NX81_002355	ENOG4105DJV	ribulose-phosphate 3-epimerase
NX81_002360	ENOG4105KD7	acetyltransferase
NX81_002445	ENOG4107TE5	Lipid kinase
NX81_002450	ENOG4105CRQ	synthase (Component I)
NX81_002465	ENOG4105DDQ	anthranilate synthase
NX81_002475	ENOG4108I0Q	anthranilate phosphoribosyltransferase
NX81_002490	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
NX81_002510	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
NX81_002540	ENOG4108UQY	Iron-storage protein
NX81_002545	ENOG4105BZU	Histidine kinase
NX81_002550	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
NX81_002570	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
NX81_002585	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
NX81_002605	ENOG4108J8Q	Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity)
NX81_002620	ENOG4105EM2	membrane
NX81_002625	ENOG4105C12	Phosphoribosylglycinamide synthetase
NX81_002635	ENOG4105DC1	bifunctional purine biosynthesis protein purh
NX81_002660	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
NX81_002705	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
NX81_002715	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
NX81_002720	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
NX81_002725	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
NX81_002730	ENOG4105VF7	tolerance protein
NX81_002740	ENOG4108K8S	endonuclease I
NX81_002750	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
NX81_002780	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
NX81_002810	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
NX81_002850	ENOG4108RDT	NADH dehydrogenase NAD(P)H nitroreductase)
NX81_002855	ENOG4108YYC	ycei family
NX81_002895	ENOG4105WSE	Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism (By similarity)
NX81_002910	ENOG41065ZS	Transfers 2'-(5-triphosphoribosyl)-3'-dephosphocoenzyme- A to the apo- acyl-carrier-protein of the malonate decarboxylase to yield holo- acyl-carrier-protein (By similarity)
NX81_002930	ENOG4105DRR	Transcriptional regulator, GntR family
NX81_002975	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
NX81_002995	ENOG4105F2I	Transposase
NX81_003030	ENOG4105PDP	Short chain dehydrogenase
NX81_003035	ENOG4105CHF	Glutathione S-transferase
NX81_003075	ENOG4107QS8	(LipO)protein
NX81_003085	ENOG4105F2I	Transposase
NX81_003115	ENOG4105DFI	Membrane
NX81_003120	ENOG4105F87	Dehydratase
NX81_003130	ENOG4108YQE	rare lipoprotein a
NX81_003145	ENOG4105C85	amino acid
NX81_003155	ENOG4105D7N	magnesium and cobalt transport protein CorA
NX81_003210	ENOG4105BZU	Histidine kinase
NX81_003220	ENOG4105C8Q	Methyl-accepting chemotaxis
NX81_003225	ENOG4105F2I	Transposase
NX81_003230	ENOG4106R7G	Glycoside hydrolase family 5
NX81_003235	ENOG4105CHH	sulfate transporter
NX81_003260	ENOG4105C3A	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity)
NX81_003270	ENOG4108HRK	Histidine kinase
NX81_003275	ENOG4108NEV	two component transcriptional regulator, LytTR family
NX81_003280	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
NX81_003335	ENOG4105F2I	Transposase
NX81_003390	ENOG4107BJW	polysaccharide deacetylase
NX81_003395	ENOG4105CND	Glycosyl transferase, family 2
NX81_003410	ENOG4105CE4	GlcNAc 6-P deacetylase
NX81_003415	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
NX81_003420	ENOG4105ETE	Transcriptional regulator (LacI family
NX81_003425	ENOG4105EDR	glucose galactose transporter
NX81_003430	ENOG4105FDP	GntR family transcriptional regulator
NX81_003445	ENOG4105CNT	hydrolase family 2
NX81_003475	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
NX81_003485	ENOG4105BZU	Histidine kinase
NX81_003495	ENOG4105BZU	Histidine kinase
NX81_003500	ENOG4105W4M	Transport-associated protein
NX81_003505	ENOG4105D9R	oxidoreductase
NX81_003515	ENOG4108J5G	6-phosphogluconate dehydrogenase
NX81_003560	ENOG4105CN1	protease
NX81_003565	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
NX81_003570	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
NX81_003585	ENOG4105DZ1	carboxypeptidase
NX81_003590	ENOG4105K6T	rare lipoprotein A
NX81_003595	ENOG4105CVE	Lytic murein transglycosylase
NX81_003625	ENOG4105F2I	Transposase
NX81_003630	ENOG41065HY	1,4-beta-cellobiosidase
NX81_003650	ENOG4105CNI	cell division protein FtsW
NX81_003665	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
NX81_003670	ENOG4105DFF	Rod shape-determining protein mreb
NX81_003685	ENOG4105CMM	transposase
NX81_003705	ENOG4105DTI	Phosphonopyruvate decarboxylase
NX81_003720	ENOG4105CAQ	asparagine synthetase
NX81_003730	ENOG4105HF0	Membrane
NX81_003765	ENOG4105CD8	aminopeptidase N
NX81_003770	ENOG4105BZU	Histidine kinase
NX81_003780	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
NX81_003805	ENOG4105F2I	Transposase
NX81_003810	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
NX81_003815	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
NX81_003825	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
NX81_003835	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
NX81_003845	ENOG4105WD1	Membrane
NX81_003870	ENOG4105F2I	Transposase
NX81_003880	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
NX81_003895	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
NX81_003905	ENOG4108K5H	permease YjgP YjgQ family protein
NX81_003915	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
NX81_003920	ENOG4105T95	Thiol disulfide interChange protein
NX81_003930	ENOG4108ETH	Formylglycinamide ribotide synthetase
NX81_003940	ENOG4105EUR	Domain-Containing protein
NX81_003950	ENOG4107QHF	type ii secretion system protein e
NX81_003960	ENOG4105D7Q	type ii secretion system
NX81_003970	ENOG4105WMT	general secretion pathway protein h
NX81_003980	ENOG41069G9	General secretion pathway protein J
NX81_003985	ENOG4105UV2	general secretion pathway protein K
NX81_003990	ENOG41090VX	general secretion pathway protein L
NX81_003995	ENOG410678M	general secretion pathway protein M
NX81_004005	ENOG4105GVR	general secretion pathway protein D
NX81_004020	ENOG4106S9K	Transcriptional regulator
NX81_004065	ENOG4107RH7	Nicotinate phosphoribosyltransferase
NX81_004095	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
NX81_004100	ENOG4105C5H	ABC transporter
NX81_004125	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
NX81_004130	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
NX81_004140	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
NX81_004150	ENOG4108R6K	riboflavin synthase, subunit alpha
NX81_004155	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
NX81_004160	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
NX81_004170	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
NX81_004210	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
NX81_004215	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
NX81_004225	ENOG4105C08	Histidine kinase
NX81_004230	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
NX81_004235	ENOG4105CQB	FAD linked oxidase domain protein
NX81_004240	ENOG4105S2T	inner membrane protein YbcI
NX81_004295	ENOG4106932	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
NX81_004300	ENOG4105CJN	penicillin-binding protein
NX81_004310	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
NX81_004315	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
NX81_004325	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
NX81_004330	ENOG4105DFU	Cell wall formation (By similarity)
NX81_004335	ENOG4105CPF	Cell wall formation (By similarity)
NX81_004340	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
NX81_004345	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
NX81_004350	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
NX81_004355	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
NX81_004365	ENOG4105DR5	peptidase
NX81_004370	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
NX81_004375	ENOG4105M6F	mutator MutT protein
NX81_004385	ENOG4105SYT	Methylenetetrahydrofolate reductase
NX81_004445	ENOG4105DXX	methyltransferase
NX81_004460	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
NX81_004485	ENOG4105D6F	Phosphatase
NX81_004490	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
NX81_004500	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
NX81_004505	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
NX81_004520	ENOG4105D9N	nucleoside
NX81_004525	ENOG4105F2I	Transposase
NX81_004535	ENOG4105F2I	Transposase
NX81_004540	ENOG4105CPC	Aldo Keto reductase
NX81_004555	ENOG4105D05	Receptor
NX81_004575	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
NX81_004590	ENOG4105E2B	Taurine dioxygenase
NX81_004600	ENOG4108I0Y	(ABC) transporter
NX81_004605	ENOG4108UJV	acyl-CoA thioesterase i
NX81_004610	ENOG4105ETX	regulatoR
NX81_004615	ENOG4105DHQ	Histidine kinase
NX81_004630	ENOG41080IJ	Diacylglycerol kinase
NX81_004650	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
NX81_004665	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
NX81_004670	ENOG4105NWN	ApaG protein
NX81_004675	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
NX81_004685	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
NX81_004695	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
NX81_004705	ENOG4108WBT	adenosyltransferase
NX81_004720	ENOG4105D0A	hydroxylase
NX81_004750	ENOG4105DDW	LysR family Transcriptional regulator
NX81_004755	ENOG4105CEY	Amp-dependent synthetase and ligase
NX81_004765	ENOG4108D7R	p-hydroxycinnamoyl CoA hydratase lyase
NX81_004810	ENOG4105DXC	membrane
NX81_004820	ENOG4105CX6	glutaminyL-tRNA synthetase
NX81_004840	ENOG4105BZU	Histidine kinase
NX81_004850	ENOG4105WH1	Two component transcriptional regulator luxr family
NX81_004870	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
NX81_004875	ENOG4105NXH	GreA GreB family elongation factor
NX81_004880	ENOG4105C5Q	Transcriptional regulator
NX81_004895	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
NX81_004940	ENOG4105C2M	dna polymerase I
NX81_004955	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
NX81_004980	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
NX81_005000	ENOG4105CM2	brancheD-chain amino acid aminotransferase
NX81_005005	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
NX81_005010	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
NX81_005015	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
NX81_005020	ENOG4108Z66	YbaK ebsC protein
NX81_005040	ENOG4105CS1	NAD(P)H quinone oxidoreductase
NX81_005045	ENOG4107S2Z	UPF0761 membrane protein
NX81_005050	ENOG4107QX9	Thiol disulfide interChange protein
NX81_005065	ENOG4105CSR	polyphosphate kinase 2
NX81_005070	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
NX81_005090	ENOG4105DJQ	tetratricopeptide tpr_2 repeat protein
NX81_005095	ENOG4105QVB	outer membrane lipoprotein LolB
NX81_005100	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
NX81_005110	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
NX81_005115	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
NX81_005120	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
NX81_005125	ENOG4105C3G	gtp-binding protein
NX81_005145	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
NX81_005155	ENOG4105PM1	preprotein translocase subunit SecE
NX81_005160	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
NX81_005165	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
NX81_005170	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
NX81_005175	ENOG4108VZM	50s ribosomal protein L10
NX81_005180	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
NX81_005185	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
NX81_005195	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
NX81_005200	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
NX81_005205	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
NX81_005210	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
NX81_005225	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
NX81_005230	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
NX81_005235	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
NX81_005240	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
NX81_005245	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NX81_005250	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
NX81_005265	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
NX81_005275	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
NX81_005280	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
NX81_005285	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
NX81_005290	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NX81_005295	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
NX81_005300	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
NX81_005315	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
NX81_005325	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
NX81_005330	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
NX81_005335	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NX81_005340	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
NX81_005345	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
NX81_005350	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
NX81_005355	ENOG4108ZT0	50S ribosomal protein l17
NX81_005360	ENOG41080I0	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
NX81_005370	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
NX81_005400	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
NX81_005405	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
NX81_005410	ENOG4108K3A	Glutathione S-transferase
NX81_005420	ENOG4105F2I	Transposase
NX81_005435	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
NX81_005440	ENOG4105CIS	alcohol dehydrogenase
NX81_005445	ENOG4105F37	PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6
NX81_005455	ENOG4108R99	pseudouridine synthase
NX81_005465	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
NX81_005470	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
NX81_005475	ENOG4108I5D	sulfate abc transporter
NX81_005485	ENOG4108IJ6	ABC transporter
NX81_005505	ENOG4105HSS	phospholipase C
NX81_005515	ENOG4105CVJ	phosphoglycerate mutase
NX81_005525	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
NX81_005540	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
NX81_005545	ENOG4105ED9	Protein of unknown function (DUF455)
NX81_005550	ENOG4108YP4	Metalloprotease, specifically cleaves on the N-terminal side of aspartyl, glutamyl and cysteic acid residues (By similarity)
NX81_005560	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
NX81_005565	ENOG4105EYK	Phosphatidylglycerophosphatase B
NX81_005570	ENOG4105BZF	Glycosyl transferase (Group 1
NX81_005575	ENOG4105C9X	ppx gppa phosphatase
NX81_005580	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
NX81_005585	ENOG4105BZU	Histidine kinase
NX81_005590	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
NX81_005595	ENOG4105ERG	peptidase m48, ste24p
NX81_005600	ENOG4105VW4	glutaredoxin 3
NX81_005615	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
NX81_005800	ENOG4105F2I	Transposase
NX81_005845	ENOG4105NVB	glycoside hydrolase, family 19
NX81_005890	ENOG4105ED4	portal protein
NX81_005940	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
NX81_005945	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
NX81_005950	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
NX81_005980	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
NX81_005995	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
NX81_006010	ENOG4107RZZ	dna polymerase iii epsilon subunit
NX81_006020	ENOG4108ZF3	Phosphatase
NX81_006035	ENOG4105DKP	glycosyl transferase, family 9
NX81_006040	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
NX81_006045	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
NX81_006050	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
NX81_006065	ENOG4105M00	molybdopterin converting factor, subunit 1
NX81_006070	ENOG4108ZAF	Molybdopterin
NX81_006085	ENOG4107QMP	dna polymerase iii subunits gamma and tau
NX81_006090	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
NX81_006100	ENOG4105K59	histidine triad (HIT) protein
NX81_006110	ENOG4105F8C	transglutaminase domain-containing protein
NX81_006120	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
NX81_006130	ENOG4105F2I	Transposase
NX81_006145	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
NX81_006150	ENOG4105VGS	50s ribosomal protein l32
NX81_006155	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
NX81_006165	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
NX81_006170	ENOG4105CHR	reductase
NX81_006180	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
NX81_006190	ENOG4105HHA	aminodeoxychorismate lyase
NX81_006195	ENOG4107QRG	dna polymerase iii
NX81_006210	ENOG4105KRQ	Addiction module toxin, Txe YoeB family
NX81_006225	ENOG4108JU7	Transcriptional regulator
NX81_006230	ENOG4105CR4	methylisocitrate lyase
NX81_006240	ENOG4105BZN	citrate synthase
NX81_006245	ENOG4108I0Z	Aconitate hydratase
NX81_006255	ENOG4105C7F	AcnD-accessory protein PrpF
NX81_006275	ENOG4105DN3	alpha-2-macroglobulin domain protein
NX81_006295	ENOG4108JQB	penicillin-binding protein 1C
NX81_006320	ENOG4105M3Z	response regulator
NX81_006325	ENOG4107QJR	hflk protein
NX81_006330	ENOG4105EPW	hflc protein
NX81_006335	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
NX81_006340	ENOG4105CD8	aminopeptidase N
NX81_006370	ENOG4105F2I	Transposase
NX81_006390	ENOG4107SCJ	type I restriction enzyme EcoKI subunit R
NX81_006435	ENOG4105CVJ	phosphoglycerate mutase
NX81_006440	ENOG4107Z4K	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
NX81_006455	ENOG4105F2I	Transposase
NX81_006460	ENOG4105BZP	glycoside hydrolase 15-related
NX81_006465	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
NX81_006485	ENOG4105CWX	Alpha-1,2-mannosidase
NX81_006490	ENOG4107GJV	short-chain dehydrogenase reductase
NX81_006545	ENOG4105C7W	Xanthine dehydrogenase
NX81_006550	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
NX81_006555	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
NX81_006590	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
NX81_006635	ENOG4105EPD	Oligopeptide transporter, Opt family
NX81_006645	ENOG4105F2I	Transposase
NX81_006665	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
NX81_006690	ENOG4106AXJ	AraC family transcriptional regulator
NX81_006765	ENOG4105CV8	reductase
NX81_006770	ENOG4105EBR	Carboxylesterase
NX81_006775	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NX81_006795	ENOG4108JJA	ABC, transporter
NX81_006800	ENOG4105C2C	drug resistance transporter, Bcr CflA
NX81_006815	ENOG4105DIJ	Phosphoethanolamine transferase
NX81_006830	ENOG4105ETX	regulatoR
NX81_006835	ENOG4105DHQ	Histidine kinase
NX81_006845	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
NX81_006850	ENOG4107QMS	site-determining protein
NX81_006855	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
NX81_006865	ENOG4105BZU	Histidine kinase
NX81_006870	ENOG4105WH1	Two component transcriptional regulator luxr family
NX81_006930	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
NX81_006950	ENOG4107RNH	Outer membrane receptor FepA
NX81_006955	ENOG4107RNH	Outer membrane receptor FepA
NX81_006970	ENOG4107RNH	Outer membrane receptor FepA
NX81_006975	ENOG4105C5H	ABC transporter
NX81_006990	ENOG4105ETT	transcriptional Regulator, LysR family
NX81_007010	ENOG4105HSS	phospholipase C
NX81_007025	ENOG4105CFQ	glutamine synthetase
NX81_007030	ENOG4105CVG	Homoserine O-transsuccinylase
NX81_007035	ENOG4108NIW	Leucine export protein LeuE
NX81_007040	ENOG4108Z86	Glutamine amidotransferase
NX81_007055	ENOG4107STF	Involved in phosphonate degradation (By similarity)
NX81_007070	ENOG4105F2I	Transposase
NX81_007075	ENOG4108ISG	Major Facilitator
NX81_007095	ENOG4105C9M	aspartyl-trna synthetase
NX81_007115	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
NX81_007120	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
NX81_007125	ENOG4105DFH	Transport of potassium into the cell (By similarity)
NX81_007135	ENOG4107YD3	Thioesterase
NX81_007140	ENOG4105E02	MotA TolQ exbB proton channel
NX81_007145	ENOG4105M8F	Biopolymer transport protein exbD tolR
NX81_007155	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
NX81_007160	ENOG4105KCK	Peptidoglycan-associated lipoprotein
NX81_007170	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
NX81_007200	ENOG4105C8Q	Methyl-accepting chemotaxis
NX81_007205	ENOG4105C8Q	Methyl-accepting chemotaxis
NX81_007255	ENOG4105C9U	ATP-dependent DNA helicase RecQ
NX81_007270	ENOG4105CQ7	ATP-dependent helicase
NX81_007285	ENOG4105CHC	glucokinase (EC 2.7.1.2)
NX81_007310	ENOG41086XE	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ (By similarity)
NX81_007315	ENOG4105JIE	May be involved in the transport of PQQ or its precursor to the periplasm (By similarity)
NX81_007320	ENOG410698T	Required for coenzyme pyrroloquinoline quinone (PQQ) biosynthesis. PQQ is probably formed by cross-linking a specific glutamate to a specific tyrosine residue and excising these residues from the peptide (By similarity)
NX81_007325	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
NX81_007350	ENOG4105BZ4	penicillin-binding protein
NX81_007360	ENOG4105DVT	helicase
NX81_007365	ENOG41072GX	Peptidase M22 Glycoprotease
NX81_007370	ENOG41065RQ	ADP-ribosylation crystallin J1
NX81_007380	ENOG4105D7Z	glutathione synthase
NX81_007385	ENOG4108UNF	response regulator
NX81_007390	ENOG4105M3Z	response regulator
NX81_007395	ENOG410807Z	Modulation of CheA activity in response to attractants (Chemotaxis
NX81_007400	ENOG4105C8Q	Methyl-accepting chemotaxis
NX81_007405	ENOG4105CBS	Chea signal transduction histidine kinase
NX81_007410	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
NX81_007425	ENOG4105D9U	N-acetyltransferase
NX81_007445	ENOG4106N3A	copper homeostasis protein cutc
NX81_007485	ENOG4105CWX	Alpha-1,2-mannosidase
NX81_007530	ENOG4108JJA	ABC, transporter
NX81_007560	ENOG4105VRS	hydrolase family 18
NX81_007575	ENOG4105CHC	glucokinase (EC 2.7.1.2)
NX81_007580	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
NX81_007590	ENOG4107RK2	ADP-ribose diphosphatase NudE
NX81_007595	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
NX81_007600	ENOG4105DXN	mazG family
NX81_007605	ENOG4105KK4	UPF0060 membrane protein
NX81_007620	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
NX81_007625	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
NX81_007665	ENOG4107QPN	acyl-Coa dehydrogenase
NX81_007675	ENOG4108IG5	Transcriptional regulator
NX81_007690	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
NX81_007710	ENOG41066T0	asmA family
NX81_007715	ENOG4108UT2	hemolysin iii
NX81_007720	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
NX81_007725	ENOG4105DR5	peptidase
NX81_007730	ENOG4106TYC	homoserine o-acetyltransferase (EC 2.3.1.31)
NX81_007735	ENOG4105C28	cystathionine
NX81_007740	ENOG4105CFH	Aspartokinase
NX81_007750	ENOG4105EJQ	L-serine dehydratase
NX81_007780	ENOG4108YYC	ycei family
NX81_007785	ENOG4105BZU	Histidine kinase
NX81_007790	ENOG4105BZU	Histidine kinase
NX81_007795	ENOG4105BZU	Histidine kinase
NX81_007800	ENOG4105BZU	Histidine kinase
NX81_007805	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
NX81_007810	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
NX81_007825	ENOG4105D49	3-dehydroquinate synthase
NX81_007830	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
NX81_007835	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
NX81_007845	ENOG4108P9J	Phage shock protein A
NX81_007870	ENOG4106032	Glutathionylspermidine synthase
NX81_007885	ENOG4108Z4X	TRANSCRIPTIONal
NX81_007940	ENOG4106N2S	
NX81_007950	ENOG4105CUB	amino acid
NX81_007970	ENOG4108J20	pectate lyase
NX81_007975	ENOG4105C85	amino acid
NX81_007985	ENOG4105C4M	(Ubiquinol oxidase) subunit I
NX81_007990	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
NX81_008000	ENOG4107UWA	esterase
NX81_008005	ENOG4105CJW	magnesium transporter
NX81_008015	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
NX81_008020	ENOG41080Z8	PHOSPHOCARRIER protein
NX81_008030	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
NX81_008035	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
NX81_008040	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
NX81_008045	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
NX81_008050	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
NX81_008055	ENOG4108IUZ	ABC transporter
NX81_008060	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
NX81_008070	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
NX81_008075	ENOG4105C2X	Arabinose 5-phosphate isomerase
NX81_008085	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
NX81_008105	ENOG4105F2I	Transposase
NX81_008120	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
NX81_008140	ENOG4105C02	permease
NX81_008150	ENOG4108S0S	Nucleotidyl transferase
NX81_008155	ENOG4105EHM	Aminoglycoside phosphotransferase
NX81_008160	ENOG4105F2I	Transposase
NX81_008170	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
NX81_008175	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
NX81_008180	ENOG41090B9	response to stress
NX81_008185	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
NX81_008190	ENOG4105CJ2	(LipO)protein
NX81_008215	ENOG4107E2E	PKHD-type hydroxylase
NX81_008220	ENOG4108ESX	Receptor
NX81_008225	ENOG4105VQD	rieske 2fe-2S domain-containing protein
NX81_008240	ENOG4105C9B	Cysteine desulfurase
NX81_008245	ENOG4105JRK	feS assembly protein SufD
NX81_008250	ENOG4105C3K	feS assembly ATPase SufC
NX81_008270	ENOG4108Z0Z	intracellular protease Pfpi family
NX81_008290	ENOG4108K5P	(LipO)protein
NX81_008300	ENOG4105II7	pyrroline-5-carboxylate reductase
NX81_008305	ENOG4105DFA	alanine racemase domain protein
NX81_008310	ENOG4105CZX	twitching motility protein
NX81_008315	ENOG4105CZX	twitching motility protein
NX81_008330	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
NX81_008335	ENOG4108UJU	UPF0301 protein
NX81_008340	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
NX81_008345	ENOG4105CXT	aspartate transcarbamylase
NX81_008355	ENOG4108Z9K	Osmotically inducible protein
NX81_008365	ENOG4105JAB	phenazine biosynthesis protein, phzf family
NX81_008370	ENOG4105JAB	phenazine biosynthesis protein, phzf family
NX81_008375	ENOG4105CFH	Aspartokinase
NX81_008400	ENOG4105EAH	synthase
NX81_008405	ENOG4108UUM	single-stranded DNA-binding protein
NX81_008425	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
NX81_008430	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
NX81_008435	ENOG4105C7W	Xanthine dehydrogenase
NX81_008440	ENOG4107XAN	XdhC and CoxI family
NX81_008475	ENOG4105VCD	cytoplasmic protein
NX81_008480	ENOG4105D22	carbon starvation protein
NX81_008485	ENOG4105EUB	pirin domain protein
NX81_008505	ENOG4105EUB	pirin domain protein
NX81_008520	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
NX81_008530	ENOG4105C9K	Endothelin-converting enzyme 1
NX81_008540	ENOG4105J12	Multidrug resistance protein mdtN
NX81_008545	ENOG4105C19	ABC transporter
NX81_008550	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
NX81_008565	ENOG4107RZC	phospholipase d
NX81_008575	ENOG4105BZU	Histidine kinase
NX81_008580	ENOG4105BZU	Histidine kinase
NX81_008585	ENOG4108V3W	Chemotaxis protein, CheW
NX81_008590	ENOG4105C8Q	Methyl-accepting chemotaxis
NX81_008600	ENOG4105CBS	Chea signal transduction histidine kinase
NX81_008675	ENOG4108JA2	transcriptioN-repair coupling factor
NX81_008685	ENOG4105D6S	protein involved in catabolism of external DNA
NX81_008690	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
NX81_008700	ENOG4105EB3	Histidine kinase
NX81_008735	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
NX81_008740	ENOG4105MYN	Zinc uptake regulation protein
NX81_008760	ENOG4105C8Y	Acetylornithine aminotransferase
NX81_008790	ENOG4105CF7	AraC family transcriptional regulator
NX81_008805	ENOG4105CC0	LysR family Transcriptional regulator
NX81_008810	ENOG4105F27	Major Facilitator
NX81_008815	ENOG4108FN7	Aldo keto reductase
NX81_008835	ENOG4105UGU	tonB-dependent Receptor
NX81_008920	ENOG4105BZU	Histidine kinase
NX81_008925	ENOG4105FE9	pseudouridine synthase
NX81_008955	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
NX81_008960	ENOG4105FQP	Beta-lactamase
NX81_008970	ENOG4105BZU	Histidine kinase
NX81_008975	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
NX81_008980	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
NX81_009005	ENOG4105BZ1	(ABC) transporter
NX81_009055	ENOG4105WG9	Conserved Protein
NX81_009075	ENOG4107QR8	Thioredoxin
NX81_009105	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
NX81_009125	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
NX81_009140	ENOG4105MPN	Membrane
NX81_009150	ENOG4105C03	ribonuclease
NX81_009155	ENOG4105QD6	exported protein
NX81_009165	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
NX81_009170	ENOG4105N42	UPF0307 protein
NX81_009175	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
NX81_009190	ENOG4105CTB	Polyprenyl synthetase
NX81_009195	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
NX81_009200	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
NX81_009205	ENOG4105G6Z	alkaline phosphatase
NX81_009210	ENOG4105CK2	sodium dicarboxylate symporter
NX81_009225	ENOG4105K4H	Nlp p60 protein
NX81_009230	ENOG4105K4H	Nlp p60 protein
NX81_009235	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
NX81_009245	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
NX81_009250	ENOG4105DC8	reductase
NX81_009270	ENOG4105C9K	Endothelin-converting enzyme 1
NX81_009275	ENOG4105C9K	Endothelin-converting enzyme 1
NX81_009285	ENOG4105F2I	Transposase
NX81_009300	ENOG4105D1F	ATP-binding protein
NX81_009310	ENOG4105DHP	deoxycytidine triphosphate deaminase
NX81_009340	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
NX81_009350	ENOG4108RRZ	Transcription elongation factor GreB
NX81_009380	ENOG4105D7A	ATP-binding protein
NX81_009395	ENOG4105DJ4	phosphatidylserine decarboxylase
NX81_009400	ENOG4105DJ4	phosphatidylserine decarboxylase
NX81_009410	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
NX81_009420	ENOG4105C5I	Dehydrogenase
NX81_009425	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
NX81_009445	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
NX81_009450	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
NX81_009460	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
NX81_009485	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
NX81_009500	ENOG4105BZU	Histidine kinase
NX81_009530	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
NX81_009535	ENOG4105CP7	Triose-phosphate isomerase
NX81_009550	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
NX81_009560	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
NX81_009570	ENOG4105GKE	subunit e
NX81_009575	ENOG4107QIZ	NADH dehydrogenase
NX81_009580	ENOG4108IEH	NADH dehydrogenase subunit g
NX81_009590	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
NX81_009595	ENOG4105DF2	NADH dehydrogenase subunit j
NX81_009605	ENOG4105D65	subunit l
NX81_009610	ENOG4105C8S	subunit m
NX81_009615	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
NX81_009625	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
NX81_009630	ENOG4105CHV	Transcription elongation factor NusA
NX81_009635	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
NX81_009640	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
NX81_009650	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
NX81_009665	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
NX81_009675	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
NX81_009680	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
NX81_009685	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
NX81_009690	ENOG4105M2J	Glutaredoxin
NX81_009700	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
NX81_009705	ENOG4108KPZ	tonB-dependent Receptor
NX81_009710	ENOG4105EWT	decarboxylase family
NX81_009715	ENOG4108HRK	Histidine kinase
NX81_009720	ENOG4105X0D	Fimbrial protein
NX81_009760	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
NX81_009795	ENOG4105CMA	conjugation trbi family protein
NX81_009815	ENOG4106E4H	Type IV secretory pathway VirB3 family protein
NX81_009850	ENOG4105F2I	Transposase
NX81_009865	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
NX81_009875	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
NX81_009880	ENOG4105J5G	Transferase hexapeptide repeat containing protein
NX81_009885	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
NX81_009895	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
NX81_009920	ENOG4108DG9	Smr protein MutS2
NX81_009925	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
NX81_009930	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
NX81_009935	ENOG4108UM1	dedA family
NX81_009940	ENOG4108K5P	(LipO)protein
NX81_009945	ENOG4108UIV	Protein of unknown function (DUF498/DUF598)
NX81_009950	ENOG4105HBR	Rna-binding protein
NX81_009955	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
NX81_009960	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
NX81_009965	ENOG4105EEI	dihydropteroate synthase
NX81_009970	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
NX81_009975	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
NX81_009980	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
NX81_009985	ENOG4107TH8	cina domain protein
NX81_009995	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
NX81_010020	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
NX81_010035	ENOG4107SDU	Methyl-accepting chemotaxis
NX81_010045	ENOG4105CWB	LysR family transcriptional Regulator
NX81_010070	ENOG4105DWF	phosphomethylpyrimidine kinase
NX81_010085	ENOG4108IAB	Phoh family
NX81_010090	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NX81_010105	ENOG4107TUS	Dihydrodipicolinate synthase
NX81_010115	ENOG4108Z4U	Ferredoxin
NX81_010120	ENOG4105EI3	2-dehydro-3-deoxygalactonokinase EC 2.7.1.58
NX81_010135	ENOG4108RTU	Aldolase
NX81_010205	ENOG4105CMG	Carbohydrate kinase
NX81_010225	ENOG4105F2I	Transposase
NX81_010230	ENOG4105F2I	Transposase
NX81_010255	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
NX81_010270	ENOG4105DJ0	Poly(A) Polymerase
NX81_010275	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NX81_010280	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
NX81_010285	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
NX81_010290	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
NX81_010295	ENOG4107QP8	phosphohexose isomerase
NX81_010335	ENOG4105BZU	Histidine kinase
NX81_010340	ENOG4105KU2	hydrolase family 5
NX81_010345	ENOG4108UYB	regulatoR
NX81_010355	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
NX81_010360	ENOG410841Q	phosphoesterase PA-phosphatase related protein
NX81_010385	ENOG4108SXK	Transporter Drug Metabolite Exporter family
NX81_010410	ENOG4105C26	Dehydrogenase
NX81_010450	ENOG4105D98	threonine synthase
NX81_010460	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
NX81_010465	ENOG4105CUT	histidyl-tRNA synthetase
NX81_010475	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
NX81_010480	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
NX81_010485	ENOG4105CIH	Imidazole acetol-phosphate transaminase
NX81_010495	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
NX81_010500	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
NX81_010505	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
NX81_010510	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
NX81_010540	ENOG4107QY0	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity)
NX81_010545	ENOG4105CUB	amino acid
NX81_010550	ENOG4105CUB	amino acid
NX81_010560	ENOG4108JQ1	Dehydrogenase
NX81_010565	ENOG4105CQB	FAD linked oxidase domain protein
NX81_010585	ENOG4105FUQ	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
NX81_010595	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
NX81_010615	ENOG4105CE1	Ferrous iron transport protein b
NX81_010630	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
NX81_010635	ENOG4108RPX	mosc domain containing protein
NX81_010645	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
NX81_010650	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
NX81_010660	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
NX81_010665	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
NX81_010675	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
NX81_010695	ENOG4105DY9	regulatoR
NX81_010705	ENOG4105CRK	lysyL-tRNA synthetase
NX81_010710	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
NX81_010715	ENOG4105BZU	Histidine kinase
NX81_010720	ENOG4105BZU	Histidine kinase
NX81_010725	ENOG4105E39	Enoyl-CoA hydratase
NX81_010730	ENOG4105CEY	Amp-dependent synthetase and ligase
NX81_010740	ENOG4107QM5	aconitate hydratase
NX81_010755	ENOG4107QIJ	Aconitate hydratase 2
NX81_010760	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
NX81_010765	ENOG4105BZU	Histidine kinase
NX81_010770	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
NX81_010780	ENOG4105BZU	Histidine kinase
NX81_010785	ENOG4105C8Q	Methyl-accepting chemotaxis
NX81_010795	ENOG4108V3W	Chemotaxis protein, CheW
NX81_010805	ENOG4105C8Q	Methyl-accepting chemotaxis
NX81_010810	ENOG4105C8Q	Methyl-accepting chemotaxis
NX81_010815	ENOG4105C8Q	Methyl-accepting chemotaxis
NX81_010825	ENOG4105C8Q	Methyl-accepting chemotaxis
NX81_010830	ENOG4105C8Q	Methyl-accepting chemotaxis
NX81_010835	ENOG4105C8Q	Methyl-accepting chemotaxis
NX81_010845	ENOG4105C8Q	Methyl-accepting chemotaxis
NX81_010855	ENOG4105F2I	Transposase
NX81_010860	ENOG4105C8Q	Methyl-accepting chemotaxis
NX81_010875	ENOG4105C8Q	Methyl-accepting chemotaxis
NX81_010880	ENOG4105C8Q	Methyl-accepting chemotaxis
NX81_010885	ENOG4105CBS	Chea signal transduction histidine kinase
NX81_010890	ENOG4108VYJ	response regulator receiver protein
NX81_010900	ENOG4108V3W	Chemotaxis protein, CheW
NX81_010905	ENOG4107QJE	Chromosome Partitioning Protein
NX81_010910	ENOG4105ER2	Ompa motb domain protein
NX81_010915	ENOG4105E14	MotA TolQ exbB proton channel
NX81_011005	ENOG4105F2I	Transposase
NX81_011025	ENOG4105CBS	Chea signal transduction histidine kinase
NX81_011035	ENOG4108VYJ	response regulator receiver protein
NX81_011040	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
NX81_011045	ENOG4107R21	site-determining protein
NX81_011050	ENOG4105FZW	flagellar biosynthesis regulator FlhF
NX81_011060	ENOG4105D7B	Flagellar biosynthesis protein flha
NX81_011065	ENOG4105D00	flagellar biosynthetic protein flhB
NX81_011070	ENOG4105BZU	Histidine kinase
NX81_011075	ENOG4105BZU	Histidine kinase
NX81_011080	ENOG4105BZU	Histidine kinase
NX81_011085	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
NX81_011090	ENOG4105VS8	Flagellar biosynthetic protein fliq
NX81_011100	ENOG4105CN7	Flagellar biosynthetic protein FliP
NX81_011105	ENOG4105K0P	flagellar biosynthesis protein
NX81_011110	ENOG4105DD5	Flagellar motor switch protein
NX81_011115	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
NX81_011135	ENOG4108JIR	Flagellum-specific ATP synthase
NX81_011145	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
NX81_011150	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
NX81_011155	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
NX81_011160	ENOG4107RGC	Glycosyl transferase, family 2
NX81_011185	ENOG4105CHR	reductase
NX81_011190	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
NX81_011195	ENOG4108P1X	synthase
NX81_011210	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
NX81_011215	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
NX81_011220	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
NX81_011240	ENOG4105MQ3	flagellar protein FliS
NX81_011245	ENOG4107W9T	flagellar hook-associated
NX81_011265	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
NX81_011270	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
NX81_011275	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
NX81_011280	ENOG4105CGA	flagellar basal-body rod protein FlgG
NX81_011290	ENOG4108KPB	Flagellar basal-body rod protein FlgF
NX81_011295	ENOG4105BZE	flagellar hook protein, FlgE
NX81_011300	ENOG410822I	Flagellar hook capping protein
NX81_011305	ENOG4108ZC9	flagellar basal-body rod protein flgc
NX81_011315	ENOG4107R88	Chemotaxis protein (CheV)
NX81_011340	ENOG4105BZU	Histidine kinase
NX81_011345	ENOG4105BZU	Histidine kinase
NX81_011350	ENOG4105BZU	Histidine kinase
NX81_011355	ENOG4105BZU	Histidine kinase
NX81_011380	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
NX81_011390	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
NX81_011395	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
NX81_011400	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
NX81_011405	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
NX81_011415	ENOG4105C3M	thioredoxin reductase
NX81_011420	ENOG4105CNU	cell division protein FtsK
NX81_011440	ENOG4105D1H	recombination factor protein RarA
NX81_011445	ENOG41082MI	Protein CrcB homolog
NX81_011450	ENOG4105CHU	acetyl-coa acetyltransferase
NX81_011465	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
NX81_011480	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
NX81_011490	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
NX81_011495	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
NX81_011505	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
NX81_011510	ENOG4105D06	uba thif-type nad fad binding protein
NX81_011535	ENOG4105F2I	Transposase
NX81_011560	ENOG4105CGK	Exodeoxyribonuclease III
NX81_011570	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
NX81_011575	ENOG41085AN	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
NX81_011585	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
NX81_011605	ENOG4108N8X	transition metal ion binding
NX81_011630	ENOG4108ZXC	Two component transcriptional regulator, luxr family
NX81_011690	ENOG4105CMM	transposase
NX81_011705	ENOG4108WC9	type VI secretion system effector, hcp1 family
NX81_011730	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
NX81_011785	ENOG4108ZF3	Phosphatase
NX81_011820	ENOG4105CA0	peroxidase
NX81_011970	ENOG41090A4	Pterin carbinolamine dehydratase
NX81_011985	ENOG4105DUN	Mediates zinc uptake. May also transport other divalent cations (By similarity)
NX81_011990	ENOG4108NST	exported protein
NX81_011995	ENOG4105EI2	Pseudouridine synthase
NX81_012000	ENOG4105C03	ribonuclease
NX81_012025	ENOG4108V1T	peptidylprolyl cis-trans isomerase
NX81_012035	ENOG4107QQG	Dehydrogenase
NX81_012065	ENOG4107QJE	Chromosome Partitioning Protein
NX81_012100	ENOG4107YH6	single-stranded DNA-binding protein
NX81_012105	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
NX81_012155	ENOG4105F2I	Transposase
NX81_012160	ENOG4105X7H	acyl-CoA dehydrogenase
NX81_012170	ENOG4105E09	nadh pyrophosphatase
NX81_012180	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
NX81_012200	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
NX81_012215	ENOG4107RSM	transcriptional regulator
NX81_012340	ENOG4106NZI	LysR family Transcriptional regulator
NX81_012370	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
NX81_012385	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
NX81_012390	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
NX81_012395	ENOG4105BZ1	(ABC) transporter
NX81_012410	ENOG4108EC8	DNA internalization-related competence protein ComEC
NX81_012425	ENOG4105D60	lipoprotein releasing system transmembrane protein
NX81_012435	ENOG410681N	tpr repeat protein
NX81_012460	ENOG410612Q	succinate dehydrogenase (cytochrome b-556 subunit)
NX81_012490	ENOG4105CHC	glucokinase (EC 2.7.1.2)
NX81_012495	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
NX81_012500	ENOG4105C01	Dihydroxy-acid dehydratase
NX81_012505	ENOG4108UHU	Aldolase
NX81_012530	ENOG4105N7H	Cytochrome
NX81_012575	ENOG4105BZU	Histidine kinase
NX81_012595	ENOG4105BZM	domain protein
NX81_012620	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
NX81_012630	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
NX81_012650	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
NX81_012665	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
NX81_012670	ENOG4108Z6B	deaminase
NX81_012675	ENOG4105KST	dependent repressor
NX81_012680	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
NX81_012695	ENOG4107SFI	Major Facilitator superfamily
NX81_012705	ENOG4105F2I	Transposase
NX81_012725	ENOG4105CHJ	isochorismatase hydrolase
NX81_012745	ENOG4105WH1	Two component transcriptional regulator luxr family
NX81_012760	ENOG4105DUM	transcriptional regulator, lysR family
NX81_012765	ENOG4105HMI	Membrane
NX81_012770	ENOG4105CHR	reductase
NX81_012780	ENOG4105EQ2	LysR family Transcriptional regulator
NX81_012785	ENOG4105DND	Transcriptional regulator
NX81_012800	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
NX81_012805	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
NX81_012810	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
NX81_012825	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
NX81_012840	ENOG4105CFV	Tetratricopeptide repeat protein
NX81_012855	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
NX81_012860	ENOG4105CAT	Cytidine monophosphate kinase
NX81_012865	ENOG4105YK5	50S ribosomal protein L36
NX81_012880	ENOG4105DWY	Agmatine deiminase
NX81_012920	ENOG4105DRS	transport system, permease
NX81_012925	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
NX81_012955	ENOG4105K9H	YciI-like protein
NX81_012960	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
NX81_012965	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
NX81_012970	ENOG4105FE9	pseudouridine synthase
NX81_012995	ENOG4105CHM	Aminotransferase
NX81_013000	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
NX81_013005	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
NX81_013010	ENOG41060IM	Heme exporter protein
NX81_013020	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
NX81_013025	ENOG4105DA4	cytochrome c-type biogenesis protein
NX81_013035	ENOG4105KWW	Biogenesis protein
NX81_013040	ENOG4108M1T	Cytochrome c-type biogenesis protein
NX81_013045	ENOG4105DWV	Homoserine O-trans-acetylase
NX81_013060	ENOG4108JJ8	(ABC) transporter
NX81_013065	ENOG4108JJ9	ABC, transporter
NX81_013100	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
NX81_013125	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
NX81_013135	ENOG4105CAS	nag kinase
NX81_013140	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
NX81_013150	ENOG4105CDH	Citrulline--aspartate ligase
NX81_013155	ENOG4105DBV	ornithine carbamoyltransferase
NX81_013175	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
NX81_013185	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
NX81_013195	ENOG4105CD3	dihydroorotase
NX81_013240	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
NX81_013245	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
NX81_013250	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
NX81_013265	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
NX81_013270	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
NX81_013275	ENOG4105BZU	Histidine kinase
NX81_013290	ENOG4105ECY	inositol monophosphatase
NX81_013295	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
NX81_013315	ENOG4105C5H	ABC transporter
NX81_013320	ENOG4105C1J	atp-dependent rna helicase
NX81_013325	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
NX81_013340	ENOG4108RXX	maleylacetoacetate isomerase
NX81_013345	ENOG4105VEQ	Cold shock protein
NX81_013355	ENOG4108VWS	Yaeq family
NX81_013360	ENOG4105CBX	hi0933 family
NX81_013380	ENOG4105CHR	reductase
NX81_013405	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
NX81_013410	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
NX81_013415	ENOG4105K8N	protein family UPF0079, ATPase
NX81_013420	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
NX81_013430	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
NX81_013445	ENOG4105E6M	Sulphatase-modifying factor protein
NX81_013465	ENOG4105DQE	DNA ligase
NX81_013490	ENOG4108V3W	Chemotaxis protein, CheW
NX81_013495	ENOG4105C8Q	Methyl-accepting chemotaxis
NX81_013515	ENOG4107QRT	dEAD DEAH box helicase
NX81_013520	ENOG4108VHC	Short-chain dehydrogenase reductase Sdr
NX81_013540	ENOG4105KB2	stringent starvation protein b
NX81_013545	ENOG4107MKT	Stringent starvation protein a
NX81_013550	ENOG4105EIX	cytochrome c1
NX81_013555	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
NX81_013560	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
NX81_013565	ENOG4105E4C	Lytic transglycosylase catalytic
NX81_013585	ENOG4105C9A	Phoh family
NX81_013610	ENOG4108JU5	Magnesium and cobalt efflux protein
NX81_013625	ENOG4105C26	Dehydrogenase
NX81_013630	ENOG4105D38	putrescine abc transporter
NX81_013635	ENOG4105F38	ABC transporter, permease
NX81_013640	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
NX81_013660	ENOG4107RUE	extracellular solute-binding protein family 1
NX81_013665	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
NX81_013680	ENOG4105CFQ	glutamine synthetase
NX81_013685	ENOG4105CJP	fad dependent oxidoreductase
NX81_013690	ENOG4105BZU	Histidine kinase
NX81_013695	ENOG4105CSH	Transporter
NX81_013710	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
NX81_013715	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
NX81_013720	ENOG4105FCD	Major Facilitator
NX81_013735	ENOG4105FDK	ABC transporter
NX81_013750	ENOG4106BRA	Membrane
NX81_013755	ENOG4105BZU	Histidine kinase
NX81_013760	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
NX81_013770	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
NX81_013775	ENOG4105C7I	Dehydrogenase
NX81_013785	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
NX81_013790	ENOG4105BZS	acriflavin resistance protein
NX81_013825	ENOG4108M60	Transcriptional regulator
NX81_013830	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
NX81_013835	ENOG4105DE4	1-phosphofructokinase
NX81_013840	ENOG4105DM4	PTS System
NX81_013870	ENOG4107QT7	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
NX81_013875	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
NX81_013880	ENOG4105VIE	preprotein translocase, subunit YajC
NX81_013885	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
NX81_013890	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
NX81_013935	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
NX81_013940	ENOG4105E08	Glycoside hydrolase, family 9
NX81_013945	ENOG4105F2I	Transposase
NX81_013960	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
NX81_013965	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
NX81_013980	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
NX81_013985	ENOG4106H78	methyltransferase
NX81_013990	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
NX81_014015	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
NX81_014085	ENOG4107QTZ	amino acid
NX81_014100	ENOG4105DC7	peptidase M24
NX81_014110	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
NX81_014125	ENOG41080HI	glycine oxidase
NX81_014130	ENOG4105CTU	Proline racemase
NX81_014140	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NX81_014150	ENOG4105CEN	a g-specific adenine glycosylase
NX81_014160	ENOG4105CQZ	Histidine kinase
NX81_014170	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
NX81_014200	ENOG4105QNF	Outer membrane lipoprotein
NX81_014210	ENOG4105CSU	acyl-Coa dehydrogenase
NX81_014220	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
NX81_014240	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
NX81_014245	ENOG4108JMX	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
NX81_014250	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
NX81_014275	ENOG4108NQK	Catalyzes the transfer of a glucuronic acid (GlcA) residue from UDP-glucuronate to mannose-alpha-1,3-glucose-beta- 1,4-glucose-P-P-polyisoprenyl to form the lipid-linked tetrasaccharide GlcA-Man-Glc(2)-PP-Pol, with a glucuronic acid- beta-mannose linkage. Is involved in the biosynthesis of the exopolysaccharide xanthan, since it catalyzes the fourth glycosylation step in the assembly of the pentasaccharide-P-P- polyisoprenyl repeating unit of xanthan. Is unable to use the trisaccharide acceptor freed from the pyrophosphate lipid moiety. Does not show specificity for the lipidic portion of the acceptor. Shows diminished activity when tested with 6-O-acetyl-mannose- alpha-1,3-glucose-beta-1,4-glucose-P-P-polyisoprenyl, a
NX81_014285	ENOG4107Y2G	Glycosyl transferase (Group 1
NX81_014310	ENOG4105D3Q	Sugar transferase
NX81_014330	ENOG4105WJX	transcriptional regulator MERR family
NX81_014335	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
NX81_014345	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
NX81_014350	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
NX81_014355	ENOG41082NX	50s ribosomal protein l35
NX81_014360	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
NX81_014365	ENOG4105C22	threonyL-tRNA synthetase
NX81_014375	ENOG4107S90	membrAne
NX81_014380	ENOG4105CJ3	phosphate transporter
NX81_014410	ENOG4105DEN	Luciferase family
NX81_014420	ENOG41079KZ	Major Facilitator Superfamily
NX81_014425	ENOG4105BZ1	(ABC) transporter
NX81_014430	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
NX81_014445	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
NX81_014485	ENOG4105EGZ	biosynthesis protein
NX81_014540	ENOG4105EMN	RNA polymerase sigma factor
NX81_014555	ENOG41060IM	Heme exporter protein
NX81_014565	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
NX81_014570	ENOG4105DA4	cytochrome c-type biogenesis protein
NX81_014575	ENOG4107QX9	Thiol disulfide interChange protein
NX81_014580	ENOG4105KWW	Biogenesis protein
NX81_014590	ENOG4105CQZ	Histidine kinase
NX81_014600	ENOG4105CQZ	Histidine kinase
NX81_014625	ENOG4105F2I	Transposase
NX81_014630	ENOG4105C8Q	Methyl-accepting chemotaxis
NX81_014675	ENOG4105W5Q	DNA repair protein (RadC
NX81_014765	ENOG4105CC0	LysR family Transcriptional regulator
NX81_014770	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
NX81_014775	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
NX81_014790	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
NX81_014800	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
NX81_014805	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
NX81_014810	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
NX81_014855	ENOG4105C84	Histidine ammonia-lyase
NX81_014865	ENOG4105CGP	Urocanate hydratase
NX81_014910	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
NX81_014915	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
NX81_014930	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
NX81_014935	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
NX81_014940	ENOG4105CIH	Imidazole acetol-phosphate transaminase
NX81_014950	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
NX81_014960	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
NX81_014965	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
NX81_014975	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
NX81_014985	ENOG4105C5S	asparaginyl-tRNA synthetase
NX81_015010	ENOG41077A9	carbonic anhydrase
NX81_015025	ENOG4105CKY	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively (By similarity)
NX81_015030	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
NX81_015035	ENOG4105CJB	Exodeoxyribonuclease I
NX81_015045	ENOG4105CPC	Aldo Keto reductase
NX81_015060	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
NX81_015065	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
NX81_015075	ENOG4105C5H	ABC transporter
NX81_015110	ENOG4105F2I	Transposase
NX81_015120	ENOG4105P8F	nudix hydrolase
NX81_015125	ENOG4108V1T	peptidylprolyl cis-trans isomerase
NX81_015130	ENOG4105E39	Enoyl-CoA hydratase
NX81_015140	ENOG4105CSM	endonuclease III
NX81_015145	ENOG4105CHH	sulfate transporter
NX81_015150	ENOG4107B2H	carbonic anhydrase
NX81_015175	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
NX81_015180	ENOG4105C8U	phosphate abc transporter
NX81_015185	ENOG4105E2Z	phosphate ABC transporter (Permease
NX81_015190	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
NX81_015195	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
NX81_015205	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
NX81_015210	ENOG4105BZU	Histidine kinase
NX81_015215	ENOG4105C2N	RNA methyltransferase TrmH family group 3
NX81_015225	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
NX81_015255	ENOG4105C1G	acyl-Coa dehydrogenase
NX81_015265	ENOG4105C3R	Methionine synthase
NX81_015280	ENOG4105D7K	pfkb domain protein
NX81_015290	ENOG4105ETE	Transcriptional regulator (LacI family
NX81_015310	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
NX81_015315	ENOG4108V1T	peptidylprolyl cis-trans isomerase
NX81_015330	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
NX81_015335	ENOG4105CZV	ABC transporter
NX81_015365	ENOG4105C37	(CBS) domain
NX81_015375	ENOG4107QTF	adenylosuccinate lyase
NX81_015400	ENOG4105EZE	Cupin 4 family protein
NX81_015410	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
NX81_015415	ENOG4105C7S	Dehydrogenase
NX81_015425	ENOG4108URH	decarboxylase
NX81_015435	ENOG4105BZ1	(ABC) transporter
NX81_015440	ENOG4105C5Q	Transcriptional regulator
NX81_015475	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
NX81_015480	ENOG4105CFG	Acts as a chaperone (By similarity)
NX81_015485	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NX81_015490	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
NX81_015495	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
NX81_015500	ENOG41090R7	Ferric uptake
NX81_015505	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
NX81_015750	ENOG4105CDU	Replicative dna helicase
NX81_015795	ENOG4105F2I	Transposase
NX81_015820	ENOG4105BZU	Histidine kinase
NX81_015830	ENOG4105BZU	Histidine kinase
NX81_015865	ENOG4105CR8	Transcriptional regulator
NX81_015870	ENOG4105CDV	Ompa motb domain protein
NX81_015875	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
NX81_015880	ENOG4105CDU	Replicative dna helicase
NX81_015890	ENOG4105CAQ	asparagine synthetase
NX81_015900	ENOG4108K3A	Glutathione S-transferase
NX81_015910	ENOG4105C1G	acyl-Coa dehydrogenase
NX81_015930	ENOG4105F8V	Hydrolase, tatD family
NX81_015935	ENOG4105CUZ	uba thif-type nad fad binding protein
NX81_015950	ENOG4105VEQ	Cold shock protein
NX81_015960	ENOG4105HDD	phospholipase
NX81_015980	ENOG4107GFK	fumarate
NX81_015990	ENOG4105DP0	ferredoxin-NADP reductase
NX81_016005	ENOG4105DGW	oligopeptidase A
NX81_016025	ENOG4105EMN	RNA polymerase sigma factor
NX81_016060	ENOG4105DUX	Transporter
NX81_016080	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
NX81_016085	ENOG4105CW7	secretion protein, HlyD family
NX81_016100	ENOG41075H3	AraC family transcriptional regulator
NX81_016105	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
NX81_016115	ENOG4105FQ6	thiopurine methyltransferase
NX81_016125	ENOG4108UWD	Iron-storage protein
NX81_016135	ENOG4108ESX	Receptor
NX81_016145	ENOG4105CAQ	asparagine synthetase
NX81_016160	ENOG4105KUZ	arsenate reductase
NX81_016175	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
NX81_016180	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
NX81_016215	ENOG4105CE9	30S ribosomal protein S2
NX81_016220	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
NX81_016225	ENOG4105BZU	Histidine kinase
NX81_016230	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
NX81_016245	ENOG4105KNE	Phosphatidate cytidylyltransferase
NX81_016255	ENOG4105DZP	Membrane-associated zinc metalloprotease
NX81_016260	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NX81_016265	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
NX81_016270	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
NX81_016275	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
NX81_016280	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
NX81_016285	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
NX81_016300	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
NX81_016315	ENOG4105NRM	Membrane
NX81_016320	ENOG4108YXA	Membrane
NX81_016370	ENOG4107QK5	Homocysteine s-methyltransferase
NX81_016375	ENOG4108IQI	permease
NX81_016380	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
NX81_016390	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
NX81_016400	ENOG4108R3D	Electron transport complex
NX81_016415	ENOG4105K6V	RNA polymerase
NX81_016440	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
NX81_016455	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
NX81_016460	ENOG4105M4H	endoribonuclease L-psp
NX81_016505	ENOG4105F27	Major Facilitator
NX81_016510	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
NX81_016555	ENOG4108YZY	peptidylprolyl cis-trans isomerase
NX81_016560	ENOG4105DFF	Rod shape-determining protein mreb
NX81_016590	ENOG4105KSC	Transcriptional regulator, TraR DksA family
NX81_016610	ENOG4108VKG	metal-dependent hydrolase
NX81_016635	ENOG4105CHU	acetyl-coa acetyltransferase
NX81_016665	ENOG4107T0X	DNA ligase
NX81_016675	ENOG4107T0X	DNA ligase
NX81_016680	ENOG4107QRT	dEAD DEAH box helicase
NX81_016695	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
NX81_016700	ENOG4105VEQ	Cold shock protein
NX81_016705	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
NX81_016710	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
NX81_016715	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
NX81_016720	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
NX81_016725	ENOG4108QDE	fad dependent oxidoreductase
NX81_016730	ENOG4107ZXU	DSBA oxidoreductase
NX81_016735	ENOG41080ZE	Adenylate cyclase
NX81_016755	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
NX81_016760	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
NX81_016770	ENOG4105C3F	Signal peptidase i
NX81_016780	ENOG4105C0H	protease
NX81_016790	ENOG4105EMN	RNA polymerase sigma factor
NX81_016810	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
NX81_016815	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
NX81_016820	ENOG4105E39	Enoyl-CoA hydratase
NX81_016825	ENOG4105C1G	acyl-Coa dehydrogenase
NX81_016830	ENOG4105C26	Dehydrogenase
NX81_016845	ENOG4106FKC	arabinogalactan endo-1,4-beta-galactosidase
NX81_016850	ENOG4105CNT	hydrolase family 2
NX81_016875	ENOG4105F2I	Transposase
NX81_016885	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
NX81_016890	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
NX81_016900	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
NX81_016915	ENOG4105VEJ	Heat shock protein
NX81_016920	ENOG4107QJQ	Mate efflux family protein
NX81_016930	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
NX81_016935	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
NX81_016940	ENOG4105K5M	30s ribosomal protein S16
NX81_016945	ENOG4105CM2	brancheD-chain amino acid aminotransferase
NX81_016950	ENOG4105EA8	2-Nitropropane dioxygenase
NX81_016960	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NX81_016965	ENOG4105CRE	cytochrome C
NX81_016970	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
NX81_016980	ENOG4105F2I	Transposase
NX81_017000	ENOG4105BZU	Histidine kinase
NX81_017005	ENOG4105BZU	Histidine kinase
NX81_017010	ENOG4107Z5C	methylesterase
NX81_017015	ENOG4105C08	Histidine kinase
NX81_017020	ENOG4105KCV	RNA signal recognition particle 4.5S RNA
NX81_017055	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
NX81_017060	ENOG4105CCU	oxidase (Subunit III)
NX81_017065	ENOG4105BZ9	Cytochrome C oxidase, subunit I
NX81_017070	ENOG4105E2S	oxidase) subunit II
NX81_017080	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
NX81_017085	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
NX81_017090	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
NX81_017095	ENOG4105DTN	riboflavin biosynthesis protein ribF
NX81_017100	ENOG4105CJR	Integral membrane protein (MviN
NX81_017105	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
NX81_017120	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
NX81_017125	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
NX81_017130	ENOG4108TGP	Thioesterase superfamily protein
NX81_017145	ENOG4105C29	acyl-CoA thioesterase
NX81_017170	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
NX81_017180	ENOG4105GAV	receptor
NX81_017195	ENOG4105C6X	Major Facilitator
NX81_017205	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
NX81_017235	ENOG4105F2I	Transposase
NX81_017245	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
NX81_017255	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
NX81_017260	ENOG4105E2Y	ABC, transporter
NX81_017265	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
NX81_017270	ENOG4105GVF	(ABC) transporter
NX81_017275	ENOG4105CPC	Aldo Keto reductase
NX81_017280	ENOG4105CPU	Monooxygenase
NX81_017290	ENOG41082IR	Excinuclease ABC C subunit domain protein
NX81_017370	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
NX81_017380	ENOG4108K4C	ec 3.1.3.12
NX81_017385	ENOG4105BZP	glycoside hydrolase 15-related
NX81_017390	ENOG4105C1K	alpha-alpha-trehalose-phosphate synthase
NX81_017395	ENOG4105DZG	Dehydrogenase
NX81_017400	ENOG4105C8Q	Methyl-accepting chemotaxis
NX81_017420	ENOG4105C34	Pseudouridine synthase
NX81_017425	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NX81_017430	ENOG4105C4K	Nad synthetase
NX81_017445	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
NX81_017450	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
NX81_017455	ENOG4107TUY	Histidine kinase
NX81_017460	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
NX81_017470	ENOG4107QHF	type ii secretion system protein e
NX81_017485	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
NX81_017490	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
NX81_017495	ENOG4105F2I	Transposase
NX81_017545	ENOG4105BZU	Histidine kinase
NX81_017550	ENOG4105ETX	regulatoR
NX81_017625	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
NX81_017630	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
NX81_017655	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
NX81_017665	ENOG4105ETE	Transcriptional regulator (LacI family
NX81_017710	ENOG4105C2N	RNA methyltransferase TrmH family group 3
NX81_017720	ENOG4105CD8	aminopeptidase N
NX81_017770	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
NX81_017780	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
NX81_017785	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
NX81_017810	ENOG4105BZU	Histidine kinase
NX81_017830	ENOG4107R11	Transcriptional regulator
NX81_017850	ENOG4108UVJ	appr-1-p processing domain protein
NX81_017855	ENOG4107R1Y	fructose-bisphosphate aldolase
NX81_017865	ENOG4105CA9	Pyruvate kinase
NX81_017900	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
NX81_017920	ENOG4105EIF	outer membrane protein W
NX81_017930	ENOG4107S76	domain protein
NX81_017935	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
NX81_017940	ENOG4105E0C	molybdate abc transporter
NX81_017945	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
NX81_017965	ENOG4107Y2H	ErfK ybiS ycfS ynhG family protein
NX81_017970	ENOG4105DR5	peptidase
NX81_017975	ENOG4105CHR	reductase
NX81_017980	ENOG4105CBN	LysR family transcriptional regulator
NX81_017985	ENOG4105CNM	Receptor
NX81_017995	ENOG4105CV1	Transketolase (EC 2.2.1.1)
NX81_018015	ENOG4107QVM	von Willebrand factor, type A
NX81_018035	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
NX81_018045	ENOG4105E4G	Type IV pilus
NX81_018070	ENOG4108JQC	penicillin-binding protein 1A
NX81_018085	ENOG4105NRA	50s ribosomal protein l31 type b
NX81_018090	ENOG4105DU0	nucleoside hydrolase
NX81_018095	ENOG4105CB5	ATP-dependent DNA helicase recG
NX81_018100	ENOG4105KME	endoribonuclease L-psp
NX81_018105	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
NX81_018110	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
NX81_018115	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
NX81_018120	ENOG4105DSJ	YicC domain protein
NX81_018125	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
NX81_018135	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
NX81_018140	ENOG4105CSA	Coproporphyrinogen iii oxidase
NX81_018155	ENOG4105D9Y	Splits dipeptides with a prolyl residue in the C- terminal position (By similarity)
NX81_018165	ENOG4107RAQ	aminopeptidase
NX81_018180	ENOG4105W8B	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
NX81_018190	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
NX81_018210	ENOG41063JG	Transcriptional regulator
NX81_018215	ENOG4105VCQ	rubredoxin
NX81_018220	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
NX81_018240	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
NX81_018250	ENOG4105F2I	Transposase
NX81_018260	ENOG41090JD	Blue (Type 1) copper domain protein
NX81_018265	ENOG4105CIH	Imidazole acetol-phosphate transaminase
NX81_018295	ENOG4105C8Y	Acetylornithine aminotransferase
NX81_018300	ENOG4105EYW	Ion transport protein
NX81_018310	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
NX81_018320	ENOG410841Q	phosphoesterase PA-phosphatase related protein
NX81_018325	ENOG4105FFC	UPF0187 protein
NX81_018335	ENOG4105DFU	Cell wall formation (By similarity)
NX81_018355	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
NX81_018365	ENOG4105F0N	pyrophosphate phospho-hydrolase
NX81_018380	ENOG4105ECQ	AraC Family Transcriptional Regulator
NX81_018385	ENOG4108M3R	transcriptional activator CadC
NX81_018405	ENOG4105C8Q	Methyl-accepting chemotaxis
NX81_018415	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
NX81_018435	ENOG4105C7B	Threonine dehydratase
NX81_018440	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
NX81_018445	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
NX81_018450	ENOG4105F2W	methyltransferase
NX81_018455	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
NX81_018460	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
NX81_018465	ENOG4108MP6	LysR family Transcriptional regulator
NX81_018475	ENOG4105BZU	Histidine kinase
NX81_018485	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
NX81_018490	ENOG4105DFG	type I secretion outer membrane protein
NX81_018495	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
NX81_018500	ENOG4105D1S	lipid A biosynthesis
NX81_018615	ENOG4105C6K	Malic enzyme
NX81_018620	ENOG4105CK2	sodium dicarboxylate symporter
NX81_018635	ENOG4105CSH	Transporter
NX81_018645	ENOG4105F04	LysR family Transcriptional regulator
NX81_018650	ENOG4105CPC	Aldo Keto reductase
NX81_018670	ENOG4105WH1	Two component transcriptional regulator luxr family
NX81_018680	ENOG4105DHQ	Histidine kinase
NX81_018700	ENOG4105D4T	Citrate transporter
NX81_018705	ENOG4105CHR	reductase
NX81_018710	ENOG4105ETE	Transcriptional regulator (LacI family
NX81_018725	ENOG4107QW3	Sucrose phosphorylase
NX81_018740	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
NX81_018745	ENOG4105CHM	Aminotransferase
NX81_018785	ENOG41069H0	dihydroorotase EC 3.5.2.3
NX81_018790	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
NX81_018850	ENOG4108QBQ	Catalyzes the condensation of formaldehyde and glutathione to S-hydroxymethylglutathione (By similarity)
NX81_018875	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
NX81_018880	ENOG4105JJR	Histidine kinase
NX81_018905	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
NX81_018910	ENOG4106RE7	Cytochrome
NX81_018920	ENOG4108Z33	Thiol disulfide Interchange Protein
NX81_018940	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
NX81_018945	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
NX81_018955	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
NX81_018965	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
NX81_018970	ENOG4105VFQ	Histone family protein nucleoid-structuring protein H-NS
NX81_018985	ENOG4105DHJ	ABC, transporter
NX81_018990	ENOG4108SNX	Mammalian cell entry related domain protein
NX81_019015	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
NX81_019035	ENOG4107QKV	phosphomannomutase
NX81_019040	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
NX81_019050	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
NX81_019065	ENOG4105BZJ	Electron transfer flavoprotein
NX81_019070	ENOG4105C10	Electron transfer flavoprotein
NX81_019080	ENOG4105F2I	Transposase
NX81_019095	ENOG4105IQ5	FAD linked oxidase domain protein
NX81_019135	ENOG4108PQP	glycosyl transferase group 1
NX81_019140	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
NX81_019145	ENOG4108DMA	Nad-dependent epimerase dehydratase
NX81_019155	ENOG4105EY8	ABC transporter
NX81_019170	ENOG4105C28	cystathionine
NX81_019195	ENOG4105CZX	twitching motility protein
NX81_019200	ENOG4108RXX	maleylacetoacetate isomerase
NX81_019215	ENOG4105C1J	atp-dependent rna helicase
NX81_019225	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
NX81_019235	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
NX81_019250	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
NX81_019255	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
NX81_019285	ENOG4105DGW	oligopeptidase A
NX81_019335	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
NX81_019340	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
NX81_019345	ENOG4105C19	ABC transporter
NX81_019350	ENOG4107RBB	ABC transporter, permease
NX81_019355	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
NX81_019365	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
NX81_019370	ENOG4105BZU	Histidine kinase
NX81_019375	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
NX81_019415	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
NX81_019420	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
NX81_019425	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
NX81_019430	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
NX81_019435	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
NX81_019440	ENOG4107RAZ	it plays a direct role in the translocation of protons across the membrane (By similarity)
NX81_019460	ENOG4107QN2	dihydrolipoyl dehydrogenase
NX81_019470	ENOG4107QSN	dihydrolipoamide acetyltransferase
NX81_019515	ENOG4105D01	(LipO)protein
NX81_019520	ENOG4108UMI	ABC transporter, permease
NX81_019525	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
NX81_019535	ENOG4108VPT	UPF0234 protein
NX81_019545	ENOG4105BZU	Histidine kinase
NX81_019560	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
NX81_019565	ENOG4107YBY	Hydrolase
NX81_019570	ENOG4105I08	Pseudouridine synthase
NX81_019575	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
NX81_019605	ENOG4105BZU	Histidine kinase
NX81_019625	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
NX81_019630	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
NX81_019635	ENOG4105EW9	transcriptional regulator AsnC family
NX81_019655	ENOG4107RD7	Flagellar Motor Protein, MotA
NX81_019660	ENOG4105ER2	Ompa motb domain protein
NX81_019675	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
NX81_019690	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
NX81_019715	ENOG4105E3A	(ABC) transporter
NX81_019720	ENOG4105DA5	(ABC) transporter
NX81_019725	ENOG4105EEQ	Na H antiporter
NX81_019740	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
NX81_019755	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
NX81_019765	ENOG4105CBN	LysR family transcriptional regulator
NX81_019775	ENOG4105CPC	Aldo Keto reductase
NX81_019785	ENOG4105C9K	Endothelin-converting enzyme 1
NX81_019800	ENOG4107QTZ	amino acid
NX81_019810	ENOG4108VAC	response regulator
NX81_019815	ENOG4105C2F	Histidine kinase
NX81_019840	ENOG4108Z9Z	response to DNA damage stimulus
NX81_019845	ENOG4105WEF	catalase
NX81_019865	ENOG4105BZU	Histidine kinase
NX81_019880	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
NX81_019895	ENOG4105C4M	(Ubiquinol oxidase) subunit I
NX81_019900	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
NX81_019915	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
NX81_019920	ENOG4105CMR	udp-glucose 4-epimerase
NX81_019940	ENOG4105BZ1	(ABC) transporter
NX81_019955	ENOG4105E2A	Dehydrogenase
NX81_020015	ENOG4105DA5	(ABC) transporter
NX81_020055	ENOG4105CMQ	Chloride channel
NX81_020095	ENOG4105NVB	glycoside hydrolase, family 19
NX81_020120	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
NX81_020165	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
NX81_020170	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
NX81_020175	ENOG4105D1S	lipid A biosynthesis
NX81_020180	ENOG4108Z7F	N-acetyltransferase
NX81_020225	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
NX81_020230	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
NX81_020235	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
NX81_020240	ENOG4108WZM	domain protein
NX81_020245	ENOG4105C79	DNA protecting protein DprA
NX81_020250	ENOG4108RPN	Protein smg homolog
NX81_020265	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
NX81_020285	ENOG4107ZQV	short-chain dehydrogenase reductase
NX81_020295	ENOG4105D07	Signal peptide peptidase, SppA
NX81_020300	ENOG4107QI1	Mate efflux family protein
NX81_020320	ENOG4105C25	Primosomal protein n'
NX81_020325	ENOG4108TGY	Glutathione S-transferase
NX81_020345	ENOG4105EN6	Membrane
NX81_020350	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
NX81_020360	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
NX81_020365	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
NX81_020370	ENOG4105CAK	Cell division ATP-binding protein ftsE
NX81_020375	ENOG4105C1J	atp-dependent rna helicase
NX81_020380	ENOG4105K63	Thioredoxin
NX81_020385	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
NX81_020395	ENOG4105VS7	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity)
NX81_020400	ENOG4105ETT	transcriptional Regulator, LysR family
NX81_020410	ENOG4105E9K	Isocitrate dehydrogenase
NX81_020420	ENOG4109066	lysm domain bon superfamily protein
NX81_020425	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
NX81_020430	ENOG4105CH2	amidohydrolase
NX81_020440	ENOG4105BZS	acriflavin resistance protein
NX81_020460	ENOG4105E32	cytoplasmic protein
NX81_020500	ENOG4108UQS	dipeptidase
NX81_020505	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
NX81_020515	ENOG4105DTQ	mandelate racemase muconate lactonizing
NX81_020530	ENOG4105D5Q	Arginine ornithine antiporter
NX81_020545	ENOG4108Z12	YiaAB two helix domain-containing protein
NX81_020555	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
NX81_020560	ENOG4107ZVW	dihydroneopterin aldolase
NX81_020570	ENOG4105VCC	30S ribosomal protein S21
NX81_020575	ENOG4105KTH	gatB Yqey
NX81_020580	ENOG4107S2Z	UPF0761 membrane protein
NX81_020585	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
NX81_020590	ENOG4105DHU	Bile acid
NX81_020625	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
NX81_020630	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
NX81_020645	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
NX81_020655	ENOG4105C26	Dehydrogenase
NX81_020695	ENOG4105DR5	peptidase
NX81_020710	ENOG4105EYM	Major Facilitator superfamily
NX81_020715	ENOG4105CGK	Exodeoxyribonuclease III
NX81_020730	ENOG4107QJE	Chromosome Partitioning Protein
NX81_020735	ENOG4105FA0	parb-like partition protein
NX81_020755	ENOG4105CKK	Glycosyl transferase, family 2
NX81_020780	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
NX81_020790	ENOG4105C75	arginyL-tRNA synthetase
NX81_020805	ENOG4105EMU	Dehydrogenase
NX81_020825	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
NX81_020830	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
NX81_020860	ENOG4108YZA	Nitrogen regulatory protein pii
NX81_020865	ENOG4105W0Z	cytoplasmic protein
NX81_020870	ENOG4105C0P	Mg chelatase subunit ChlI
NX81_020885	ENOG41066DG	(EAL) domain protein
NX81_020900	ENOG4105EJ2	Transcriptional regulator
NX81_020910	ENOG4105E0Y	RtcB Protein
NX81_020955	ENOG4105ECP	epimerase
NX81_020965	ENOG4105C0H	protease
NX81_020985	ENOG4105C02	permease
NX81_020990	ENOG4107URF	beta-phospho-glucomutase
NX81_020995	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
NX81_021010	ENOG4107VGR	Catalase
NX81_021025	ENOG4108S01	response regulator
NX81_021030	ENOG4105F2I	Transposase
NX81_021035	ENOG4108ZGX	Histidine kinase
NX81_021040	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
NX81_021050	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
NX81_021075	ENOG4105FDR	Membrane
NX81_021100	ENOG4108NNI	Beta-lactamase domain-containing protein
NX81_021105	ENOG4105C31	Tryptophanyl-tRNA synthetase
NX81_021110	ENOG4105VDW	Csbd family
NX81_021175	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
NX81_021205	ENOG4105EB3	Histidine kinase
NX81_021210	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
NX81_021220	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
NX81_021530	ENOG4105CH6	catalase
NX81_021545	ENOG4105DVT	helicase
NX81_021560	ENOG4105E2X	shikimate dehydrogenase
NX81_021575	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
NX81_021600	ENOG4105D52	delta-aminolevulinic acid dehydratase
NX81_021640	ENOG4105CYM	Glutathione S-transferase
NX81_021660	ENOG4105QV4	Tryptophan halogenase
NX81_021675	ENOG4108IUW	ABC transporter
NX81_021690	ENOG4105VZ8	Transcriptional regulator
NX81_021705	ENOG4105PGM	cation diffusion facilitator family transporter
NX81_021710	ENOG4107SC0	ferredoxin--NADP reductase
NX81_021715	ENOG4105DA5	(ABC) transporter
NX81_021720	ENOG4105E3A	(ABC) transporter
NX81_021730	ENOG41063V1	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
NX81_021775	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
NX81_021780	ENOG4107QYD	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
NX81_021795	ENOG4105CD5	CoA-binding domain protein
NX81_021810	ENOG4105CJW	magnesium transporter
NX81_021825	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
NX81_021830	ENOG4105BZP	glycoside hydrolase 15-related
NX81_021850	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
NX81_021860	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
NX81_021905	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
NX81_021910	ENOG4105E9Q	Acyl-transferase
NX81_021920	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
NX81_021970	ENOG4105JAS	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene) (By similarity)
NX81_021975	ENOG4108JPW	Aminotransferase
NX81_022010	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
NX81_022015	ENOG4105C2M	dna polymerase I
NX81_022060	ENOG4105C4R	Atp-dependent dna helicase
NX81_022075	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
NX81_022085	ENOG4105KHM	amidohydrolase 2
NX81_022095	ENOG4105W0E	50S ribosomal protein L33
NX81_022100	ENOG4105KDC	50s ribosomal protein l28
NX81_022110	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
NX81_022135	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
NX81_022165	ENOG4105CGK	Exodeoxyribonuclease III
NX81_022170	ENOG41061DF	Catalyzes the phosphorylation of N-acetylmannosamine (ManNAc) to ManNAc-6-P (By similarity)
NX81_022180	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
NX81_022190	ENOG4107QN1	sodium solute
NX81_022195	ENOG41062QD	Membrane
NX81_022260	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
NX81_022265	ENOG4105ERH	Fumarylacetoacetate hydrolase
NX81_022270	ENOG4105DIA	mandelate racemase muconate lactonizing
NX81_022275	ENOG4105QJH	Domain of unknown function (DUF718)
NX81_022280	ENOG4105EDR	glucose galactose transporter
NX81_022285	ENOG4108K2P	TRANSCRIPTIONal
NX81_022300	ENOG4105BZU	Histidine kinase
NX81_022310	ENOG4105E2V	Glycosyltransferase 36
NX81_022315	ENOG4105CT4	transporter
NX81_022320	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
NX81_022350	ENOG4105MA0	exported protein
NX81_022355	ENOG4105CFU	surface antigen
NX81_022360	ENOG4105D05	Receptor
NX81_022365	ENOG4107RDJ	Sulfotransferase
NX81_022375	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
NX81_022380	ENOG4107QHF	type ii secretion system protein e
NX81_022395	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
NX81_022405	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
NX81_022410	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
NX81_022425	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
NX81_022445	ENOG4105DH7	May be involved in recombination (By similarity)
NX81_022450	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
NX81_022465	ENOG4105ETE	Transcriptional regulator (LacI family
NX81_022470	ENOG4105D0H	Alpha-glucuronidase (EC 3.2.1.139)
NX81_022480	ENOG4105CXK	mandelate racemase muconate lactonizing
NX81_022495	ENOG4105DEI	Mannitol dehydrogenase
NX81_022560	ENOG4105D9F	endo-1,4-beta-xylanase (EC 3.2.1.8)
NX81_022580	ENOG4105D2H	Uronic isomerase
NX81_022605	ENOG4105CT4	transporter
NX81_022610	ENOG4105DT9	hydrolase family 43
NX81_022645	ENOG4105E55	glycerol-3-phosphate acyltransferase
NX81_022655	ENOG4105ETE	Transcriptional regulator (LacI family
NX81_022670	ENOG4105QV4	Tryptophan halogenase
NX81_022675	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
NX81_022680	ENOG4105CUR	5'-nucleotidase, lipoprotein e(p4) family
NX81_022685	ENOG4108YXG	UPF0502 protein
NX81_022700	ENOG4105C4R	Atp-dependent dna helicase
NX81_022705	ENOG4107104	thymidine kinase
NX81_022715	ENOG4105DJ9	glucan biosynthesis protein
NX81_022725	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
NX81_022755	ENOG4105DKK	Benzoate
NX81_022780	ENOG4105DSB	aldose 1-epimerase
NX81_022790	ENOG4105K5B	UPF0225 protein
NX81_022795	ENOG4105EJ9	Membrane
NX81_022815	ENOG4105EUJ	GTP cyclohydrolase i
NX81_022825	ENOG4105ZQC	membrane protein AaeX
NX81_022830	ENOG4105Y49	secretion protein, HlyD family
NX81_022840	ENOG4105DR8	Membrane
NX81_022845	ENOG4105CSH	Transporter
NX81_022855	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
NX81_022920	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
NX81_022965	ENOG4105VDM	plasmid maintenance system antidote protein, xre family
NX81_022975	ENOG4107QYX	exodeoxyribonuclease v alpha
NX81_022980	ENOG4107QKA	exodeoxyribonuclease V beta
NX81_022985	ENOG4105DSY	exodeoxyribonuclease V, gamma
NX81_022990	ENOG4105DHJ	ABC, transporter
NX81_022995	ENOG4105CY3	ABC transporter, permease
NX81_023000	ENOG4107PE3	Mammalian cell entry related domain protein
NX81_023015	ENOG410903C	(LipO)protein
NX81_023025	ENOG4108V06	Glutathione peroxidase
NX81_023040	ENOG4107QSV	RmuC domain protein
NX81_023045	ENOG4105CIS	alcohol dehydrogenase
NX81_023050	ENOG4105EJC	lysr family transcriptional regulator
NX81_023075	ENOG4105CUB	amino acid
NX81_023090	ENOG4105NRM	Membrane
NX81_023095	ENOG4105BZU	Histidine kinase
NX81_023100	ENOG4108IXP	Carbohydrate diacid transcriptional activator CdaR
NX81_023105	ENOG4105BZW	Glycerate kinase
NX81_023110	ENOG4105CSP	Major Facilitator Superfamily
NX81_023130	ENOG4105DR4	Methyltransferase
NX81_023140	ENOG4105DU1	integral membrane protein, terc
NX81_023150	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
NX81_023175	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NX81_023190	ENOG4105K63	Thioredoxin
NX81_023210	ENOG4105BZU	Histidine kinase
NX81_023220	ENOG4105QD0	anti-sigma regulatory factor serine threonine protein kinase
NX81_023225	ENOG4105FUA	antagonist
NX81_023230	ENOG4107MMM	Anti-sigma-factor antagonist
NX81_023240	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
NX81_023260	ENOG4105KAF	membrAne
NX81_023265	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
NX81_023275	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
NX81_023280	ENOG4105CCU	oxidase (Subunit III)
NX81_023285	ENOG4105BZ9	Cytochrome C oxidase, subunit I
NX81_023290	ENOG4105E2S	oxidase) subunit II
NX81_023300	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
NX81_023305	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
NX81_023505	ENOG4106N2S	
NX81_023515	ENOG4108C33	Resolvase
NX81_023590	ENOG4105CMA	conjugation trbi family protein
NX81_023600	ENOG4105BZ9	Cytochrome C oxidase, subunit I
NX81_023605	ENOG4105CCU	oxidase (Subunit III)
NX81_023610	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
NX81_023620	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
NX81_023625	ENOG4105KAF	membrAne