locus-tag	class	description
NX81_000010	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NX81_000025	COG0187	DNA topoisomerase II activity
NX81_000035	COG0501	Belongs to the peptidase M48B family
NX81_000065	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
NX81_000075	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NX81_000120	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NX81_000125	COG0793	Belongs to the peptidase S41A family
NX81_000130	COG4942	peptidase
NX81_000140	COG2234	aminopeptidase activity
NX81_000150	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
NX81_000155	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
NX81_000160	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
NX81_000170	COG1064	alcohol dehydrogenase
NX81_000185	COG0493	'glutamate synthase
NX81_000190	COG0067	glutamate synthase
NX81_000190	COG0070	glutamate synthase
NX81_000190	COG0069	glutamate synthase activity
NX81_000275	COG1205	dead DEAH box helicase
NX81_000275	COG1111	helicase
NX81_000280	COG1272	protein, Hemolysin III
NX81_000325	COG2816	NAD+ diphosphatase activity
NX81_000340	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NX81_000390	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
NX81_000410	COG4772	TonB-dependent receptor
NX81_000435	COG1304	FMN binding
NX81_000450	COG1755	Isoprenylcysteine carboxyl methyltransferase
NX81_000455	COG4585	Histidine kinase
NX81_000460	COG2197	response regulator
NX81_000480	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
NX81_000530	COG3039	Transposase
NX81_000540	COG2831	hemolysin activation secretion protein
NX81_000550	COG0366	Alpha amylase catalytic
NX81_000555	COG0366	Alpha amylase catalytic
NX81_000580	COG2755	lipolytic protein G-D-S-L family
NX81_000580	COG0657	acetylesterase activity
NX81_000590	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
NX81_000605	COG3507	Belongs to the glycosyl hydrolase 43 family
NX81_000610	COG1609	Transcriptional regulator
NX81_000615	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
NX81_000620	COG1028	Short-chain dehydrogenase reductase Sdr
NX81_000630	COG2755	lipolytic protein G-D-S-L family
NX81_000640	COG3186	Phenylalanine-4-hydroxylase
NX81_000645	COG1522	sequence-specific DNA binding
NX81_000660	COG2951	lytic endotransglycosylase activity
NX81_000665	COG1752	Esterase of the alpha-beta hydrolase superfamily
NX81_000670	COG1473	amidohydrolase
NX81_000680	COG1119	ATPase activity
NX81_000695	COG0517	IMP dehydrogenase activity
NX81_000695	COG1125	glycine betaine transport
NX81_000710	COG1262	PFAM Formylglycine-generating sulfatase enzyme
NX81_000740	COG0489	protein tyrosine kinase activity
NX81_000745	COG2062	phosphohistidine phosphatase, SixA
NX81_000755	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NX81_000810	COG0174	glutamine synthetase
NX81_000815	COG0347	Belongs to the P(II) protein family
NX81_000820	COG0004	ammonium transporteR
NX81_000825	COG3852	Histidine kinase
NX81_000830	COG2204	response regulator
NX81_000835	COG2032	superoxide dismutase activity
NX81_000840	COG2032	superoxide dismutase activity
NX81_000850	COG0346	lactoylglutathione lyase activity
NX81_000860	COG0183	Belongs to the thiolase family
NX81_000900	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NX81_000905	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
NX81_000910	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
NX81_000920	COG0028	Belongs to the TPP enzyme family
NX81_000925	COG2205	protein histidine kinase activity
NX81_000950	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
NX81_000965	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NX81_000970	COG3177	Filamentation induced by cAMP protein fic
NX81_000985	COG0596	Alpha beta hydrolase
NX81_000995	COG0318	PFAM AMP-dependent synthetase and ligase
NX81_001000	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NX81_001020	COG1181	Belongs to the D-alanine--D-alanine ligase family
NX81_001040	COG0564	pseudouridine synthase activity
NX81_001065	COG0339	signal peptide processing
NX81_001105	COG0583	DNA-binding transcription factor activity
NX81_001110	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
NX81_001115	COG2224	Isocitrate lyase
NX81_001120	COG3706	GGDEF domain
NX81_001150	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NX81_001155	COG1960	acyl-CoA dehydrogenase activity
NX81_001210	COG0523	cobalamin synthesis protein
NX81_001220	COG0697	spore germination
NX81_001230	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
NX81_001240	COG1846	Transcriptional regulator
NX81_001245	COG1764	response to oxidative stress
NX81_001265	COG0656	L-ascorbic acid biosynthetic process
NX81_001270	COG2130	NADP-dependent
NX81_001285	COG1187	pseudouridine synthase activity
NX81_001295	COG1643	Atp-dependent helicase
NX81_001300	COG4807	Protein conserved in bacteria
NX81_001305	COG2351	hydroxyisourate hydrolase activity
NX81_001310	COG2072	flavoprotein involved in K transport
NX81_001330	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
NX81_001375	COG2252	PERMEase
NX81_001395	COG0084	hydrolase, TatD family'
NX81_001430	COG0583	DNA-binding transcription factor activity
NX81_001440	COG4221	oxidoreductase activity
NX81_001450	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
NX81_001455	COG1902	pentaerythritol trinitrate reductase activity
NX81_001480	COG0745	RESPONSE REGULATOR receiver
NX81_001500	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NX81_001505	COG0583	DNA-binding transcription factor activity
NX81_001540	COG0702	epimerase
NX81_001545	COG1733	regulation of RNA biosynthetic process
NX81_001595	COG3039	Transposase
NX81_001620	COG0129	dihydroxy-acid dehydratase activity
NX81_001635	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
NX81_001690	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NX81_001695	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
NX81_001725	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NX81_001730	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
NX81_001740	COG3485	protocatechuate 3,4-dioxygenase
NX81_001745	COG3485	protocatechuate 3,4-dioxygenase
NX81_001760	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NX81_001765	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NX81_001770	COG1414	Transcriptional regulator
NX81_001785	COG0445	tRNA wobble uridine modification
NX81_001845	COG0156	8-amino-7-oxononanoate synthase activity
NX81_001850	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NX81_001855	COG1040	competence protein
NX81_001890	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
NX81_001985	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NX81_002055	COG1511	domain protein
NX81_002055	COG3264	Mechanosensitive ion channel
NX81_002060	COG1368	sulfuric ester hydrolase activity
NX81_002070	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
NX81_002075	COG2354	Protein conserved in bacteria
NX81_002085	COG0745	RESPONSE REGULATOR receiver
NX81_002085	COG3706	GGDEF domain
NX81_002090	COG0297	glycogen (starch) synthase activity
NX81_002095	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NX81_002100	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NX81_002125	COG0702	epimerase
NX81_002130	COG1028	Short-chain dehydrogenase reductase Sdr
NX81_002155	COG0513	Belongs to the DEAD box helicase family
NX81_002170	COG0508	dehydrogenase complex catalyzes the overall conversion of
NX81_002185	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
NX81_002205	COG3104	oligopeptide transport
NX81_002225	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
NX81_002265	COG1320	monovalent cation:proton antiporter activity
NX81_002270	COG2212	antiporter activity
NX81_002280	COG0651	ATP synthesis coupled electron transport
NX81_002285	COG1006	Multisubunit Na H antiporter MnhC subunit
NX81_002290	COG2111	Na H antiporter
NX81_002290	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NX81_002340	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
NX81_002345	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
NX81_002355	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
NX81_002360	COG0456	acetyltransferase
NX81_002370	COG0582	viral genome integration into host DNA
NX81_002445	COG1597	lipid kinase activity
NX81_002475	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NX81_002480	COG0134	indole-3-glycerol-phosphate synthase activity
NX81_002490	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NX81_002510	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NX81_002550	COG0745	RESPONSE REGULATOR receiver
NX81_002570	COG0316	Belongs to the HesB IscA family
NX81_002585	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
NX81_002605	COG2814	Major facilitator Superfamily
NX81_002615	COG2814	Major facilitator Superfamily
NX81_002620	COG1289	transmembrane transporter activity
NX81_002625	COG0151	Belongs to the GarS family
NX81_002635	COG0138	bifunctional purine biosynthesis protein purh
NX81_002660	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
NX81_002705	COG0439	Biotin carboxylase
NX81_002715	COG0511	ligase activity, forming carbon-carbon bonds
NX81_002720	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
NX81_002730	COG1324	tolerance protein
NX81_002740	COG2356	endonuclease I
NX81_002750	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NX81_002780	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NX81_002800	COG3386	PFAM SMP-30 Gluconolaconase
NX81_002810	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
NX81_002850	COG0778	Nitroreductase
NX81_002855	COG2353	YceI-like domain
NX81_002895	COG3052	prosthetic group binding
NX81_002930	COG1802	Transcriptional regulator
NX81_002995	COG3039	Transposase
NX81_003010	COG2963	transposase activity
NX81_003030	COG4221	oxidoreductase activity
NX81_003035	COG0435	Glutathione S-transferase
NX81_003085	COG3039	Transposase
NX81_003115	COG0697	spore germination
NX81_003130	COG4305	rare lipoprotein A
NX81_003145	COG1113	amino acid transport
NX81_003155	COG0598	Magnesium transport protein CorA
NX81_003220	COG0840	transmembrane signaling receptor activity
NX81_003225	COG3039	Transposase
NX81_003230	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
NX81_003230	COG5297	Belongs to the glycosyl hydrolase family 6
NX81_003235	COG0659	secondary active sulfate transmembrane transporter activity
NX81_003260	COG2943	transferase activity, transferring hexosyl groups
NX81_003270	COG3275	phosphorelay sensor kinase activity
NX81_003280	COG0181	hydroxymethylbilane synthase activity
NX81_003310	COG1505	serine-type exopeptidase activity
NX81_003335	COG3039	Transposase
NX81_003390	COG1649	PFAM Uncharacterised BCR, COG1649
NX81_003390	COG0726	polysaccharide deacetylase
NX81_003395	COG1215	transferase activity, transferring glycosyl groups
NX81_003410	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
NX81_003415	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
NX81_003420	COG1609	Transcriptional regulator
NX81_003425	COG0738	Major facilitator superfamily
NX81_003445	COG3250	beta-galactosidase activity
NX81_003475	COG1028	Short-chain dehydrogenase reductase Sdr
NX81_003480	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NX81_003485	COG4191	Histidine kinase
NX81_003490	COG0784	Response regulator, receiver
NX81_003495	COG4251	negative regulation of phosphorylation
NX81_003500	COG2823	Periplasmic or secreted lipoprotein
NX81_003505	COG0673	inositol 2-dehydrogenase activity
NX81_003515	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
NX81_003550	COG1051	belongs to the nudix hydrolase family
NX81_003550	COG1056	cytidyltransferase-related domain
NX81_003565	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NX81_003570	COG0321	lipoyl(octanoyl) transferase activity
NX81_003585	COG1686	Belongs to the peptidase S11 family
NX81_003590	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
NX81_003595	COG2951	lytic endotransglycosylase activity
NX81_003625	COG3039	Transposase
NX81_003630	COG5297	Belongs to the glycosyl hydrolase family 6
NX81_003650	COG0772	Belongs to the SEDS family
NX81_003665	COG1792	Involved in formation and maintenance of cell shape
NX81_003670	COG1077	Cell shape determining protein MreB Mrl
NX81_003685	COG2801	Transposase and inactivated derivatives
NX81_003705	COG0028	Belongs to the TPP enzyme family
NX81_003705	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
NX81_003720	COG0367	asparagine synthase
NX81_003725	COG1012	belongs to the aldehyde dehydrogenase family
NX81_003730	COG0730	response to heat
NX81_003765	COG0308	aminopeptidase N
NX81_003770	COG5001	Diguanylate cyclase
NX81_003770	COG3300	MHYT domain
NX81_003780	COG2226	methyltransferase
NX81_003805	COG3039	Transposase
NX81_003810	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
NX81_003815	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
NX81_003825	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
NX81_003835	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NX81_003845	COG2832	Protein of unknown function (DUF454)
NX81_003870	COG3039	Transposase
NX81_003880	COG0525	valine-tRNA ligase activity
NX81_003895	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NX81_003905	COG0795	lipopolysaccharide-transporting ATPase activity
NX81_003915	COG4974	Belongs to the 'phage' integrase family
NX81_003920	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NX81_003930	COG0047	phosphoribosylformylglycinamidine synthase activity
NX81_003930	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NX81_003940	COG5295	Hep Hag repeat protein
NX81_003950	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NX81_003960	COG1459	type II secretion system
NX81_003965	COG2165	general secretion pathway protein
NX81_003970	COG4970	Tfp pilus assembly protein FimT
NX81_003975	COG2165	general secretion pathway protein
NX81_003980	COG4795	General secretion pathway protein
NX81_003985	COG3156	type II secretion system protein K
NX81_003990	COG3166	PFAM Fimbrial assembly family protein
NX81_004005	COG1450	Type ii and iii secretion system protein
NX81_004020	COG2188	Transcriptional regulator
NX81_004065	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NX81_004095	COG0242	peptide deformylase activity
NX81_004100	COG0488	(ABC) transporter
NX81_004125	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NX81_004130	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NX81_004140	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NX81_004140	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NX81_004160	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
NX81_004170	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
NX81_004210	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
NX81_004215	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
NX81_004225	COG2205	protein histidine kinase activity
NX81_004230	COG0745	RESPONSE REGULATOR receiver
NX81_004235	COG0277	FAD linked oxidase domain protein
NX81_004240	COG1988	membrane-bound metal-dependent
NX81_004295	COG3116	cell division
NX81_004310	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
NX81_004315	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NX81_004325	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NX81_004330	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
NX81_004335	COG1181	Belongs to the D-alanine--D-alanine ligase family
NX81_004340	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
NX81_004355	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
NX81_004365	COG0739	heme binding
NX81_004370	COG0653	protein targeting
NX81_004375	COG0494	nUDIX hydrolase
NX81_004385	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
NX81_004395	COG0604	alcohol dehydrogenase
NX81_004395	COG3321	synthase
NX81_004395	COG1028	Short-chain dehydrogenase reductase Sdr
NX81_004445	COG2226	methyltransferase
NX81_004460	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
NX81_004490	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NX81_004500	COG4106	trans-aconitate 2-methyltransferase activity
NX81_004505	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NX81_004520	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NX81_004525	COG3039	Transposase
NX81_004535	COG3039	Transposase
NX81_004540	COG0667	Aldo Keto reductase
NX81_004555	COG4771	TonB-dependent receptor
NX81_004575	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NX81_004580	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
NX81_004590	COG2175	clavaminate synthase activity
NX81_004600	COG4181	ATPase activity
NX81_004615	COG0642	Histidine kinase
NX81_004630	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
NX81_004650	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NX81_004665	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
NX81_004670	COG2967	ApaG domain
NX81_004675	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
NX81_004685	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
NX81_004695	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
NX81_004700	COG0123	including yeast histone deacetylase and acetoin utilization protein
NX81_004705	COG2096	Adenosyltransferase
NX81_004720	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NX81_004725	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NX81_004745	COG3384	dioxygenase
NX81_004750	COG0583	DNA-binding transcription factor activity
NX81_004755	COG0318	PFAM AMP-dependent synthetase and ligase
NX81_004765	COG1024	Enoyl-CoA hydratase
NX81_004785	COG3386	PFAM SMP-30 Gluconolaconase
NX81_004810	COG0697	spore germination
NX81_004820	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NX81_004840	COG3706	GGDEF domain
NX81_004840	COG0745	RESPONSE REGULATOR receiver
NX81_004850	COG2197	response regulator
NX81_004860	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NX81_004870	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NX81_004875	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NX81_004880	COG0583	DNA-binding transcription factor activity
NX81_004885	COG3634	alkyl hydroperoxide reductase activity
NX81_004895	COG2890	protein-(glutamine-N5) methyltransferase activity
NX81_004940	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NX81_004940	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NX81_004955	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
NX81_004980	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
NX81_005000	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NX81_005005	COG1404	Belongs to the peptidase S8 family
NX81_005010	COG1404	Belongs to the peptidase S8 family
NX81_005015	COG1404	Belongs to the peptidase S8 family
NX81_005020	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NX81_005045	COG1295	ribonuclease BN
NX81_005050	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NX81_005070	COG0521	Mo-molybdopterin cofactor biosynthetic process
NX81_005085	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
NX81_005095	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
NX81_005100	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NX81_005110	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NX81_005115	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
NX81_005120	COG0193	aminoacyl-tRNA hydrolase activity
NX81_005125	COG0012	GTP binding
NX81_005145	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NX81_005155	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
NX81_005160	COG0250	Participates in transcription elongation, termination and antitermination
NX81_005165	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NX81_005170	COG0081	regulation of translation
NX81_005175	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NX81_005185	COG0085	RNA polymerase activity
NX81_005195	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NX81_005200	COG0049	tRNA binding
NX81_005205	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NX81_005210	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NX81_005225	COG0051	transcription antitermination factor activity, RNA binding
NX81_005235	COG0088	Forms part of the polypeptide exit tunnel
NX81_005245	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NX81_005265	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NX81_005270	COG0255	Belongs to the universal ribosomal protein uL29 family
NX81_005275	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NX81_005280	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NX81_005285	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NX81_005295	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NX81_005315	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NX81_005320	COG1841	ribosomal large subunit assembly
NX81_005325	COG0200	Binds to the 23S rRNA
NX81_005330	COG0201	protein transport
NX81_005335	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NX81_005340	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NX81_005345	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NX81_005350	COG0202	RNA polymerase activity
NX81_005355	COG0203	ribosomal protein L17
NX81_005360	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
NX81_005370	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
NX81_005400	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NX81_005410	COG0625	glutathione transferase activity
NX81_005420	COG3039	Transposase
NX81_005435	COG1902	pentaerythritol trinitrate reductase activity
NX81_005435	COG0446	pyridine nucleotide-disulphide oxidoreductase
NX81_005440	COG0604	alcohol dehydrogenase
NX81_005445	COG2885	chlorophyll binding
NX81_005465	COG0156	8-amino-7-oxononanoate synthase activity
NX81_005470	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
NX81_005475	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
NX81_005480	COG4208	sulfate ABC transporter
NX81_005485	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
NX81_005515	COG0406	alpha-ribazole phosphatase activity
NX81_005525	COG0285	dihydrofolate synthase activity
NX81_005545	COG2833	Protein of unknown function (DUF455)
NX81_005550	COG3291	Pkd domain containing protein
NX81_005560	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NX81_005565	COG0671	phosphoesterase, PA-phosphatase related
NX81_005570	COG0438	transferase activity, transferring glycosyl groups
NX81_005580	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
NX81_005595	COG4783	chaperone-mediated protein folding
NX81_005615	COG0473	3-isopropylmalate dehydrogenase activity
NX81_005800	COG3039	Transposase
NX81_005845	COG3179	chitinase
NX81_005890	COG4695	Portal protein
NX81_005940	COG0544	peptidyl-prolyl cis-trans isomerase activity
NX81_005945	COG0740	serine-type endopeptidase activity
NX81_005950	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NX81_005980	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NX81_005995	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NX81_006010	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NX81_006020	COG0631	protein serine/threonine phosphatase activity
NX81_006035	COG0859	PFAM glycosyl transferase family 9
NX81_006040	COG3642	lipopolysaccharide core region biosynthetic process
NX81_006045	COG1234	tRNA 3'-trailer cleavage
NX81_006050	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NX81_006065	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
NX81_006070	COG0314	molybdopterin synthase activity
NX81_006090	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NX81_006100	COG0537	adenosine 5'-monophosphoramidase activity
NX81_006120	COG0714	Associated with various cellular activities
NX81_006130	COG3039	Transposase
NX81_006145	COG1399	metal-binding, possibly nucleic acid-binding protein
NX81_006155	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NX81_006170	COG1028	Short-chain dehydrogenase reductase Sdr
NX81_006185	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NX81_006190	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NX81_006210	COG4115	mRNA cleavage
NX81_006225	COG3829	transcription factor binding
NX81_006245	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NX81_006275	COG2373	Large extracellular alpha-helical protein
NX81_006295	COG4953	penicillin-binding protein 1C
NX81_006305	COG0678	peroxiredoxin activity
NX81_006325	COG0330	HflC and HflK could
NX81_006330	COG0330	HflC and HflK could
NX81_006335	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NX81_006340	COG0308	aminopeptidase N
NX81_006370	COG3039	Transposase
NX81_006390	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
NX81_006435	COG0328	RNA-DNA hybrid ribonuclease activity
NX81_006435	COG0406	alpha-ribazole phosphatase activity
NX81_006440	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
NX81_006455	COG3039	Transposase
NX81_006460	COG3387	PFAM Glycoside hydrolase 15-related
NX81_006465	COG1028	Short-chain dehydrogenase reductase Sdr
NX81_006485	COG3537	Alpha-1,2-mannosidase
NX81_006490	COG4221	oxidoreductase activity
NX81_006545	COG1529	Aldehyde oxidase and xanthine dehydrogenase
NX81_006550	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
NX81_006555	COG2080	2 iron, 2 sulfur cluster binding
NX81_006590	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NX81_006605	COG0587	DNA-directed DNA polymerase activity
NX81_006635	COG1297	OPT oligopeptide transporter protein
NX81_006645	COG3039	Transposase
NX81_006665	COG0823	Involved in the tonB-independent uptake of proteins
NX81_006665	COG1506	peptidase
NX81_006690	COG2207	Transcriptional regulator
NX81_006690	COG1917	Cupin 2, conserved barrel domain protein
NX81_006760	COG0753	catalase activity
NX81_006765	COG0656	L-ascorbic acid biosynthetic process
NX81_006770	COG2272	Belongs to the type-B carboxylesterase lipase family
NX81_006775	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NX81_006775	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NX81_006800	COG2814	Major facilitator Superfamily
NX81_006815	COG2194	sulfuric ester hydrolase activity
NX81_006830	COG0745	RESPONSE REGULATOR receiver
NX81_006835	COG0642	Histidine kinase
NX81_006845	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
NX81_006850	COG2894	cell division
NX81_006855	COG0850	regulation of cytokinetic process
NX81_006865	COG4585	Histidine kinase
NX81_006870	COG2197	response regulator
NX81_006885	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
NX81_006915	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NX81_006930	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
NX81_006975	COG0488	(ABC) transporter
NX81_007025	COG0174	glutamine synthetase
NX81_007030	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
NX81_007040	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
NX81_007070	COG3039	Transposase
NX81_007075	COG0477	Major facilitator Superfamily
NX81_007095	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NX81_007115	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
NX81_007125	COG3158	transport of potassium into the cell
NX81_007135	COG0824	Thioesterase
NX81_007145	COG0848	biopolymer transport protein
NX81_007155	COG0823	Involved in the tonB-independent uptake of proteins
NX81_007160	COG2885	chlorophyll binding
NX81_007170	COG0602	queuosine metabolic process
NX81_007200	COG0840	transmembrane signaling receptor activity
NX81_007205	COG0840	transmembrane signaling receptor activity
NX81_007220	COG1187	pseudouridine synthase activity
NX81_007255	COG0514	ATP-dependent DNA helicase (RecQ)
NX81_007265	COG0783	Belongs to the Dps family
NX81_007270	COG1643	Atp-dependent helicase
NX81_007285	COG0837	glucose binding
NX81_007310	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
NX81_007315	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
NX81_007325	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NX81_007340	COG1215	transferase activity, transferring glycosyl groups
NX81_007350	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NX81_007360	COG1199	ATP-dependent helicase activity
NX81_007370	COG1397	ADP-ribosylglycohydrolase
NX81_007380	COG0189	ligase activity
NX81_007395	COG0835	chemotaxis
NX81_007400	COG0840	transmembrane signaling receptor activity
NX81_007410	COG2201	protein-glutamate methylesterase activity
NX81_007440	COG1446	asparaginase
NX81_007445	COG3142	Participates in the control of copper homeostasis
NX81_007485	COG3537	Alpha-1,2-mannosidase
NX81_007535	COG1472	Belongs to the glycosyl hydrolase 3 family
NX81_007560	COG3858	chitin binding
NX81_007560	COG1388	LysM domain
NX81_007575	COG0837	glucose binding
NX81_007580	COG1385	rRNA (uridine-N3-)-methyltransferase activity
NX81_007590	COG0494	nUDIX hydrolase
NX81_007600	COG3956	TIGRFAM MazG family protein
NX81_007605	COG1742	UPF0060 membrane protein
NX81_007620	COG0404	The glycine cleavage system catalyzes the degradation of glycine
NX81_007625	COG0509	glycine decarboxylation via glycine cleavage system
NX81_007665	COG1960	acyl-CoA dehydrogenase activity
NX81_007670	COG2267	carboxylic ester hydrolase activity
NX81_007675	COG1309	transcriptional regulator
NX81_007690	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NX81_007700	COG0463	Glycosyl transferase, family 2
NX81_007710	COG2982	Protein involved in outer membrane biogenesis
NX81_007715	COG1272	protein, Hemolysin III
NX81_007720	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NX81_007725	COG0739	heme binding
NX81_007730	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NX81_007735	COG0626	cystathionine gamma-synthase activity
NX81_007740	COG0527	aspartate kinase activity
NX81_007740	COG0460	homoserine dehydrogenase
NX81_007750	COG1760	l-serine dehydratase
NX81_007780	COG2353	YceI-like domain
NX81_007785	COG2205	protein histidine kinase activity
NX81_007785	COG2198	Histidine kinase
NX81_007785	COG0784	Response regulator, receiver
NX81_007790	COG0784	Response regulator, receiver
NX81_007790	COG5002	protein histidine kinase activity
NX81_007805	COG0477	Major facilitator Superfamily
NX81_007810	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
NX81_007825	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NX81_007830	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NX81_007835	COG0259	pyridoxamine-phosphate oxidase activity
NX81_007845	COG1842	Phage shock protein A
NX81_007870	COG0754	glutathionylspermidine amidase activity
NX81_007880	COG2814	Major facilitator Superfamily
NX81_007885	COG0789	Transcriptional regulator
NX81_007950	COG0531	amino acid
NX81_007955	COG2197	response regulator
NX81_007970	COG3866	Pectate lyase
NX81_007975	COG1113	amino acid transport
NX81_007985	COG1271	oxidase subunit
NX81_007990	COG1294	oxidase, subunit
NX81_008005	COG2239	Acts as a magnesium transporter
NX81_008015	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NX81_008020	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NX81_008030	COG1660	Displays ATPase and GTPase activities
NX81_008040	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NX81_008055	COG1137	ATPase activity
NX81_008060	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
NX81_008070	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
NX81_008080	COG0271	Belongs to the BolA IbaG family
NX81_008085	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NX81_008105	COG3039	Transposase
NX81_008120	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NX81_008140	COG0628	permease
NX81_008150	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
NX81_008155	COG3178	'Phosphotransferase
NX81_008160	COG3039	Transposase
NX81_008170	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NX81_008175	COG1555	photosystem II stabilization
NX81_008185	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NX81_008190	COG1477	protein flavinylation
NX81_008215	COG3128	pkhd-type hydroxylase
NX81_008220	COG4774	siderophore transport
NX81_008240	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NX81_008245	COG0719	Fe-S assembly protein
NX81_008250	COG0396	ATPase activity
NX81_008255	COG0719	Fe-S assembly protein
NX81_008260	COG1959	2 iron, 2 sulfur cluster binding
NX81_008270	COG0693	protein deglycase activity
NX81_008290	COG4942	peptidase
NX81_008305	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NX81_008330	COG0519	Catalyzes the synthesis of GMP from XMP
NX81_008335	COG1678	Uncharacterized ACR, COG1678
NX81_008340	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NX81_008345	COG0540	Belongs to the ATCase OTCase family
NX81_008355	COG1764	response to oxidative stress
NX81_008365	COG0384	phenazine biosynthesis protein PhzF
NX81_008370	COG0384	phenazine biosynthesis protein PhzF
NX81_008375	COG0527	aspartate kinase activity
NX81_008400	COG0142	geranyltranstransferase activity
NX81_008405	COG0629	single-stranded DNA binding
NX81_008410	COG3706	GGDEF domain
NX81_008410	COG4251	negative regulation of phosphorylation
NX81_008410	COG5001	Diguanylate cyclase
NX81_008410	COG2203	Gaf domain
NX81_008415	COG3321	synthase
NX81_008415	COG1028	Short-chain dehydrogenase reductase Sdr
NX81_008415	COG0604	alcohol dehydrogenase
NX81_008425	COG2080	2 iron, 2 sulfur cluster binding
NX81_008430	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
NX81_008435	COG1529	Aldehyde oxidase and xanthine dehydrogenase
NX81_008440	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
NX81_008475	COG2879	small protein
NX81_008480	COG1966	Carbon starvation protein
NX81_008485	COG1741	Belongs to the pirin family
NX81_008505	COG1741	Belongs to the pirin family
NX81_008520	COG0588	phosphoglycerate mutase activity
NX81_008530	COG3590	peptidase
NX81_008540	COG1566	PFAM secretion protein HlyD family protein
NX81_008545	COG1136	(ABC) transporter
NX81_008550	COG1136	(ABC) transporter
NX81_008550	COG0577	efflux transmembrane transporter activity
NX81_008565	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NX81_008575	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
NX81_008585	COG0835	chemotaxis
NX81_008590	COG0840	transmembrane signaling receptor activity
NX81_008600	COG0643	Histidine kinase
NX81_008600	COG2198	Histidine kinase
NX81_008675	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NX81_008685	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
NX81_008690	COG0745	RESPONSE REGULATOR receiver
NX81_008700	COG2205	protein histidine kinase activity
NX81_008735	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NX81_008740	COG0735	belongs to the Fur family
NX81_008760	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NX81_008790	COG2207	Transcriptional regulator
NX81_008805	COG0583	DNA-binding transcription factor activity
NX81_008810	COG2814	Major facilitator Superfamily
NX81_008815	COG0667	Aldo Keto reductase
NX81_008920	COG5001	Diguanylate cyclase
NX81_008920	COG5002	protein histidine kinase activity
NX81_008925	COG1187	pseudouridine synthase activity
NX81_008955	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
NX81_008960	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NX81_008965	COG0475	glutathione-regulated potassium exporter activity
NX81_008970	COG5002	protein histidine kinase activity
NX81_008970	COG5000	phosphorelay sensor kinase activity
NX81_008975	COG0745	RESPONSE REGULATOR receiver
NX81_009005	COG1132	(ABC) transporter
NX81_009055	COG2155	Conserved Protein
NX81_009075	COG3118	belongs to the thioredoxin family
NX81_009105	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NX81_009125	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NX81_009140	COG2968	Membrane
NX81_009150	COG1530	ribonuclease E activity
NX81_009155	COG3164	Protein of unknown function
NX81_009165	COG0312	modulator of DNA gyrase
NX81_009175	COG0312	modulator of DNA gyrase
NX81_009185	COG4104	PAAR repeat-containing protein
NX81_009190	COG0142	geranyltranstransferase activity
NX81_009195	COG1722	exodeoxyribonuclease VII activity
NX81_009200	COG0037	tRNA processing
NX81_009205	COG1785	Belongs to the alkaline phosphatase family
NX81_009210	COG1301	dicarboxylic acid transport
NX81_009225	COG0791	NLP P60 protein
NX81_009230	COG0791	NLP P60 protein
NX81_009235	COG1047	Peptidyl-prolyl cis-trans
NX81_009240	COG2311	Membrane
NX81_009245	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NX81_009250	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NX81_009270	COG3590	peptidase
NX81_009275	COG3590	peptidase
NX81_009285	COG3039	Transposase
NX81_009300	COG0489	protein tyrosine kinase activity
NX81_009310	COG0717	Belongs to the dCTP deaminase family
NX81_009340	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NX81_009350	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NX81_009380	COG0433	COG0433 Predicted ATPase
NX81_009395	COG0688	phosphatidylethanolamine metabolic process
NX81_009400	COG0688	phosphatidylethanolamine metabolic process
NX81_009410	COG2890	protein-(glutamine-N5) methyltransferase activity
NX81_009420	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NX81_009425	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NX81_009445	COG0101	tRNA pseudouridine synthase activity
NX81_009450	COG0135	phosphoribosylanthranilate isomerase activity
NX81_009460	COG0133	tryptophan synthase activity
NX81_009485	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NX81_009530	COG1028	Short-chain dehydrogenase reductase Sdr
NX81_009535	COG0149	triose-phosphate isomerase activity
NX81_009550	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NX81_009560	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NX81_009570	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
NX81_009575	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
NX81_009580	COG1034	ATP synthesis coupled electron transport
NX81_009585	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
NX81_009590	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NX81_009600	COG0713	ATP synthesis coupled electron transport
NX81_009615	COG1007	ATP synthesis coupled electron transport
NX81_009625	COG0779	Required for maturation of 30S ribosomal subunits
NX81_009630	COG0195	Participates in both transcription termination and antitermination
NX81_009635	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NX81_009640	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NX81_009650	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NX81_009690	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
NX81_009700	COG2095	MarC family integral membrane protein
NX81_009710	COG1611	Belongs to the LOG family
NX81_009715	COG3275	phosphorelay sensor kinase activity
NX81_009760	COG0556	nucleotide-excision repair
NX81_009775	COG3505	Type IV secretory pathway VirD4
NX81_009795	COG2948	multi-organism process
NX81_009815	COG3702	type iv secretory pathway
NX81_009850	COG3039	Transposase
NX81_009875	COG0504	CTP synthase activity
NX81_009895	COG0148	phosphopyruvate hydratase activity
NX81_009920	COG2840	Smr protein MutS2
NX81_009925	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
NX81_009930	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
NX81_009935	COG1238	metal cluster binding
NX81_009945	COG3737	Protein of unknown function (DUF498/DUF598)
NX81_009950	COG1534	Rna-binding protein
NX81_009955	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
NX81_009960	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NX81_009965	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NX81_009970	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NX81_009975	COG1923	regulation of RNA biosynthetic process
NX81_009980	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NX81_009985	COG1546	Belongs to the CinA family
NX81_010010	COG2137	regulation of response to DNA damage stimulus
NX81_010020	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
NX81_010040	COG1741	Belongs to the pirin family
NX81_010045	COG0583	DNA-binding transcription factor activity
NX81_010070	COG0352	thiamine-phosphate diphosphorylase activity
NX81_010070	COG0351	phosphomethylpyrimidine kinase
NX81_010085	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
NX81_010090	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NX81_010105	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NX81_010115	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
NX81_010120	COG3734	2-keto-3-deoxy-galactonokinase
NX81_010135	COG0800	Aldolase
NX81_010195	COG1501	Belongs to the glycosyl hydrolase 31 family
NX81_010205	COG1070	Carbohydrate kinase
NX81_010215	COG0477	Major facilitator Superfamily
NX81_010225	COG3039	Transposase
NX81_010230	COG3039	Transposase
NX81_010255	COG1469	GTP cyclohydrolase I activity
NX81_010270	COG0617	tRNA 3'-terminal CCA addition
NX81_010280	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
NX81_010285	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
NX81_010290	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
NX81_010315	COG1472	Belongs to the glycosyl hydrolase 3 family
NX81_010340	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
NX81_010345	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
NX81_010355	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
NX81_010360	COG0671	phosphoesterase, PA-phosphatase related
NX81_010375	COG1794	racemase activity, acting on amino acids and derivatives
NX81_010385	COG0697	spore germination
NX81_010390	COG0812	UDP-N-acetylmuramate dehydrogenase activity
NX81_010410	COG1012	belongs to the aldehyde dehydrogenase family
NX81_010450	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NX81_010460	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NX81_010465	COG0124	histidyl-tRNA synthetase
NX81_010475	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
NX81_010480	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NX81_010485	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NX81_010495	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NX81_010500	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NX81_010505	COG0107	imidazoleglycerol-phosphate synthase activity
NX81_010510	COG0140	phosphoribosyl-ATP diphosphatase activity
NX81_010510	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NX81_010540	COG0235	Class ii aldolase
NX81_010545	COG0531	amino acid
NX81_010550	COG0531	amino acid
NX81_010560	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NX81_010565	COG0277	FAD linked oxidase domain protein
NX81_010585	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NX81_010630	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NX81_010635	COG2258	MOSC domain
NX81_010645	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
NX81_010650	COG0505	Belongs to the CarA family
NX81_010660	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
NX81_010665	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NX81_010675	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
NX81_010695	COG3279	Response regulator of the LytR AlgR family
NX81_010705	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
NX81_010720	COG0784	Response regulator, receiver
NX81_010720	COG2198	Histidine kinase
NX81_010720	COG2205	protein histidine kinase activity
NX81_010725	COG1024	Enoyl-CoA hydratase
NX81_010730	COG0318	PFAM AMP-dependent synthetase and ligase
NX81_010760	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NX81_010770	COG2201	protein-glutamate methylesterase activity
NX81_010785	COG0840	transmembrane signaling receptor activity
NX81_010795	COG0835	chemotaxis
NX81_010805	COG0840	transmembrane signaling receptor activity
NX81_010810	COG0840	transmembrane signaling receptor activity
NX81_010815	COG0840	transmembrane signaling receptor activity
NX81_010825	COG0840	transmembrane signaling receptor activity
NX81_010830	COG0840	transmembrane signaling receptor activity
NX81_010835	COG0840	transmembrane signaling receptor activity
NX81_010840	COG0840	transmembrane signaling receptor activity
NX81_010845	COG0840	transmembrane signaling receptor activity
NX81_010855	COG3039	Transposase
NX81_010860	COG0840	transmembrane signaling receptor activity
NX81_010875	COG0840	transmembrane signaling receptor activity
NX81_010880	COG0840	transmembrane signaling receptor activity
NX81_010890	COG0745	RESPONSE REGULATOR receiver
NX81_010900	COG0835	chemotaxis
NX81_010905	COG1192	Involved in chromosome partitioning
NX81_010910	COG1360	Flagellar Motor Protein
NX81_010915	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
NX81_011005	COG3039	Transposase
NX81_011025	COG0643	Histidine kinase
NX81_011025	COG2198	Histidine kinase
NX81_011045	COG0455	bacterial-type flagellum organization
NX81_011075	COG5001	Diguanylate cyclase
NX81_011075	COG3300	MHYT domain
NX81_011080	COG3300	MHYT domain
NX81_011080	COG5001	Diguanylate cyclase
NX81_011085	COG1684	flagellar biosynthetic protein fliR
NX81_011090	COG1987	bacterial-type flagellum assembly
NX81_011105	COG3190	flagellar
NX81_011155	COG1677	Flagellar hook-basal body complex protein FliE
NX81_011185	COG1028	Short-chain dehydrogenase reductase Sdr
NX81_011190	COG1028	Short-chain dehydrogenase reductase Sdr
NX81_011195	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NX81_011210	COG2204	response regulator
NX81_011215	COG2201	protein-glutamate methylesterase activity
NX81_011245	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
NX81_011250	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NX81_011270	COG1706	bacterial-type flagellum-dependent cell motility
NX81_011275	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
NX81_011280	COG4786	Flagellar basal body rod
NX81_011290	COG4787	bacterial-type flagellum-dependent cell motility
NX81_011295	COG1749	Flagellar hook protein flgE
NX81_011300	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
NX81_011305	COG1558	bacterial-type flagellum-dependent cell motility
NX81_011315	COG0784	Response regulator, receiver
NX81_011315	COG0835	chemotaxis
NX81_011340	COG5002	protein histidine kinase activity
NX81_011350	COG4585	Histidine kinase
NX81_011380	COG0482	sulfurtransferase activity
NX81_011390	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
NX81_011395	COG0542	response to heat
NX81_011400	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NX81_011405	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
NX81_011415	COG0492	ferredoxin-NADP+ reductase activity
NX81_011420	COG1674	ftsk spoiiie
NX81_011440	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
NX81_011445	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NX81_011450	COG0183	Belongs to the thiolase family
NX81_011455	COG1250	3-hydroxyacyl-CoA dehydrogenase
NX81_011455	COG1024	Enoyl-CoA hydratase
NX81_011465	COG0105	UTP biosynthetic process
NX81_011490	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NX81_011495	COG1160	GTP binding
NX81_011505	COG0303	'Molybdopterin
NX81_011510	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NX81_011535	COG3039	Transposase
NX81_011560	COG0708	Exodeoxyribonuclease III
NX81_011570	COG0303	'Molybdopterin
NX81_011575	COG0746	molybdenum cofactor guanylyltransferase activity
NX81_011585	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NX81_011585	COG1648	precorrin-2 dehydrogenase activity
NX81_011605	COG3685	Protein conserved in bacteria
NX81_011620	COG5001	Diguanylate cyclase
NX81_011630	COG4566	intracellular signal transduction
NX81_011690	COG2801	Transposase and inactivated derivatives
NX81_011750	COG3501	Rhs element vgr protein
NX81_011785	COG0631	protein serine/threonine phosphatase activity
NX81_011820	COG1858	cytochrome C peroxidase
NX81_011970	COG2154	pterin-4-alpha-carbinolamine dehydratase
NX81_011985	COG0428	transporter
NX81_011990	COG3064	Membrane
NX81_012000	COG1530	ribonuclease E activity
NX81_012035	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
NX81_012065	COG1192	Involved in chromosome partitioning
NX81_012100	COG0629	single-stranded DNA binding
NX81_012105	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NX81_012155	COG3039	Transposase
NX81_012160	COG1960	acyl-CoA dehydrogenase activity
NX81_012170	COG2816	NAD+ diphosphatase activity
NX81_012180	COG2814	Major facilitator Superfamily
NX81_012200	COG1028	Short-chain dehydrogenase reductase Sdr
NX81_012215	COG0583	DNA-binding transcription factor activity
NX81_012340	COG0583	DNA-binding transcription factor activity
NX81_012345	COG1396	sequence-specific DNA binding
NX81_012355	COG0582	viral genome integration into host DNA
NX81_012370	COG0322	excinuclease ABC activity
NX81_012380	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NX81_012385	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
NX81_012390	COG1663	tetraacyldisaccharide 4'-kinase activity
NX81_012395	COG1132	(ABC) transporter
NX81_012405	COG0811	peptide transport
NX81_012425	COG4591	ABC-type transport system involved in lipoprotein release permease component
NX81_012435	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
NX81_012440	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
NX81_012455	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
NX81_012485	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NX81_012490	COG0837	glucose binding
NX81_012495	COG0363	glucosamine-6-phosphate deaminase activity
NX81_012500	COG0129	dihydroxy-acid dehydratase activity
NX81_012505	COG0800	Aldolase
NX81_012575	COG0784	Response regulator, receiver
NX81_012575	COG2205	protein histidine kinase activity
NX81_012595	COG2183	response to ionizing radiation
NX81_012605	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NX81_012605	COG0723	plastoquinol--plastocyanin reductase activity
NX81_012620	COG3243	poly(R)-hydroxyalkanoic acid synthase
NX81_012630	COG1183	phosphatidylcholine synthase activity
NX81_012635	COG1028	Short-chain dehydrogenase reductase Sdr
NX81_012650	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
NX81_012660	COG0668	transmembrane transport
NX81_012665	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
NX81_012670	COG0590	tRNA wobble adenosine to inosine editing
NX81_012675	COG1321	iron dependent repressor
NX81_012680	COG1914	H( )-stimulated, divalent metal cation uptake system
NX81_012695	COG2814	Major facilitator Superfamily
NX81_012705	COG3039	Transposase
NX81_012725	COG1335	isochorismatase
NX81_012745	COG2197	response regulator
NX81_012760	COG0583	DNA-binding transcription factor activity
NX81_012770	COG1028	Short-chain dehydrogenase reductase Sdr
NX81_012780	COG0583	DNA-binding transcription factor activity
NX81_012785	COG0583	DNA-binding transcription factor activity
NX81_012790	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NX81_012810	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NX81_012825	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NX81_012840	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
NX81_012855	COG0539	negative regulation of cytoplasmic translation
NX81_012860	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
NX81_012865	COG0257	Belongs to the bacterial ribosomal protein bL36 family
NX81_012880	COG2957	Belongs to the agmatine deiminase family
NX81_012890	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NX81_012920	COG0395	ABC-type sugar transport system, permease component
NX81_012925	COG1175	transmembrane transport
NX81_012955	COG2350	Protein conserved in bacteria
NX81_012960	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NX81_012965	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NX81_012970	COG1187	pseudouridine synthase activity
NX81_012995	COG0436	Aminotransferase
NX81_013000	COG4133	protoheme IX ABC transporter activity
NX81_013020	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
NX81_013045	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NX81_013050	COG1278	Cold shock
NX81_013060	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
NX81_013065	COG4988	ABC transporter
NX81_013100	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NX81_013125	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NX81_013135	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
NX81_013140	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NX81_013150	COG0137	argininosuccinate synthase activity
NX81_013155	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NX81_013175	COG2166	iron-sulfur cluster assembly
NX81_013185	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
NX81_013195	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
NX81_013245	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NX81_013250	COG0402	S-adenosylhomocysteine deaminase activity
NX81_013265	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NX81_013270	COG1509	lysine 2,3-aminomutase activity
NX81_013275	COG3300	MHYT domain
NX81_013275	COG5001	Diguanylate cyclase
NX81_013290	COG0483	inositol monophosphate 1-phosphatase activity
NX81_013320	COG0513	Belongs to the DEAD box helicase family
NX81_013325	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NX81_013340	COG0625	glutathione transferase activity
NX81_013355	COG4681	YaeQ
NX81_013360	COG2081	HI0933 family
NX81_013370	COG0501	Belongs to the peptidase M48B family
NX81_013380	COG1028	Short-chain dehydrogenase reductase Sdr
NX81_013405	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NX81_013410	COG0860	N-Acetylmuramoyl-L-alanine amidase
NX81_013415	COG0802	atpase or kinase
NX81_013420	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NX81_013420	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
NX81_013430	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NX81_013445	COG1262	PFAM Formylglycine-generating sulfatase enzyme
NX81_013490	COG0835	chemotaxis
NX81_013495	COG0840	transmembrane signaling receptor activity
NX81_013515	COG1201	RNA secondary structure unwinding
NX81_013520	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
NX81_013540	COG2969	positive regulation of protein catabolic process
NX81_013545	COG0625	glutathione transferase activity
NX81_013550	COG2857	Cytochrome c1
NX81_013555	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
NX81_013560	COG0723	plastoquinol--plastocyanin reductase activity
NX81_013565	COG0741	lytic transglycosylase activity
NX81_013585	COG1702	phosphate starvation-inducible protein PhoH
NX81_013610	COG4535	Mg2 and Co2 transporter CorC
NX81_013625	COG1012	belongs to the aldehyde dehydrogenase family
NX81_013630	COG1177	transmembrane transport
NX81_013635	COG1176	ABC-type spermidine putrescine transport system, permease component I
NX81_013640	COG3842	ATPase activity
NX81_013660	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
NX81_013675	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
NX81_013680	COG0174	glutamine synthetase
NX81_013685	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NX81_013690	COG0745	RESPONSE REGULATOR receiver
NX81_013690	COG3706	GGDEF domain
NX81_013695	COG0477	Major facilitator Superfamily
NX81_013710	COG0243	molybdopterin cofactor binding
NX81_013715	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
NX81_013735	COG1121	(ABC) transporter
NX81_013750	COG2733	membrane
NX81_013755	COG5002	protein histidine kinase activity
NX81_013755	COG2205	protein histidine kinase activity
NX81_013755	COG0784	Response regulator, receiver
NX81_013770	COG0477	Major facilitator Superfamily
NX81_013775	COG2902	Dehydrogenase
NX81_013785	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NX81_013790	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NX81_013825	COG1609	Transcriptional regulator
NX81_013830	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
NX81_013830	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NX81_013835	COG1105	Belongs to the carbohydrate kinase PfkB family
NX81_013840	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NX81_013840	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NX81_013870	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NX81_013880	COG1862	Preprotein translocase
NX81_013885	COG0343	queuine tRNA-ribosyltransferase activity
NX81_013890	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NX81_013935	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NX81_013940	COG3291	Pkd domain containing protein
NX81_013945	COG3039	Transposase
NX81_013960	COG0405	Gamma-glutamyltransferase
NX81_013965	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
NX81_013980	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NX81_013985	COG0742	ribosomal rna small subunit methyltransferase
NX81_013990	COG0326	Molecular chaperone. Has ATPase activity
NX81_014015	COG4206	TonB-dependent receptor
NX81_014085	COG0531	amino acid
NX81_014100	COG0006	proline dipeptidase activity
NX81_014110	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NX81_014125	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NX81_014130	COG3938	Belongs to the proline racemase family
NX81_014140	COG0552	protein localization to endoplasmic reticulum
NX81_014160	COG0784	Response regulator, receiver
NX81_014160	COG4191	Histidine kinase
NX81_014170	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NX81_014200	COG3040	lipid binding
NX81_014210	COG1960	acyl-CoA dehydrogenase activity
NX81_014220	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NX81_014240	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NX81_014245	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NX81_014250	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NX81_014285	COG0438	transferase activity, transferring glycosyl groups
NX81_014290	COG0438	transferase activity, transferring glycosyl groups
NX81_014335	COG0776	regulation of translation
NX81_014345	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NX81_014350	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NX81_014355	COG0291	Belongs to the bacterial ribosomal protein bL35 family
NX81_014360	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NX81_014365	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NX81_014375	COG1434	Gram-negative-bacterium-type cell wall biogenesis
NX81_014380	COG0306	phosphate transporter
NX81_014395	COG1253	flavin adenine dinucleotide binding
NX81_014410	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NX81_014420	COG0477	Major facilitator Superfamily
NX81_014425	COG1132	(ABC) transporter
NX81_014430	COG1136	(ABC) transporter
NX81_014445	COG0438	transferase activity, transferring glycosyl groups
NX81_014485	COG2244	polysaccharide biosynthetic process
NX81_014555	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NX81_014565	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
NX81_014575	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NX81_014590	COG0784	Response regulator, receiver
NX81_014590	COG4191	Histidine kinase
NX81_014595	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
NX81_014600	COG4191	Histidine kinase
NX81_014600	COG0784	Response regulator, receiver
NX81_014625	COG3039	Transposase
NX81_014630	COG0840	transmembrane signaling receptor activity
NX81_014675	COG2003	Belongs to the UPF0758 family
NX81_014765	COG0583	DNA-binding transcription factor activity
NX81_014770	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NX81_014775	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NX81_014790	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
NX81_014795	COG1605	Chorismate mutase
NX81_014795	COG0077	Prephenate dehydratase
NX81_014800	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NX81_014805	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
NX81_014810	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
NX81_014855	COG2986	histidine ammonia-lyase
NX81_014865	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
NX81_014915	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
NX81_014930	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
NX81_014935	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NX81_014940	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NX81_014950	COG3115	cell septum assembly
NX81_014975	COG0316	Belongs to the HesB IscA family
NX81_014985	COG0017	Asparaginyl-tRNA synthetase
NX81_015010	COG0288	reversible hydration of carbon dioxide
NX81_015025	COG3844	kynureninase activity
NX81_015030	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NX81_015035	COG2925	Exonuclease
NX81_015045	COG0667	Aldo Keto reductase
NX81_015060	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NX81_015065	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
NX81_015065	COG0116	Belongs to the methyltransferase superfamily
NX81_015110	COG3039	Transposase
NX81_015120	COG0494	nUDIX hydrolase
NX81_015130	COG1024	Enoyl-CoA hydratase
NX81_015140	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NX81_015145	COG0659	secondary active sulfate transmembrane transporter activity
NX81_015175	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
NX81_015180	COG0573	inorganic phosphate transmembrane transporter activity
NX81_015185	COG0581	inorganic phosphate transmembrane transporter activity
NX81_015190	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
NX81_015195	COG0704	Plays a role in the regulation of phosphate uptake
NX81_015205	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NX81_015210	COG3706	GGDEF domain
NX81_015215	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NX81_015225	COG0557	exoribonuclease II activity
NX81_015255	COG1960	acyl-CoA dehydrogenase activity
NX81_015265	COG1410	methionine synthase
NX81_015265	COG0646	methionine synthase
NX81_015280	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NX81_015320	COG0386	Belongs to the glutathione peroxidase family
NX81_015330	COG1725	Transcriptional regulator
NX81_015335	COG1131	(ABC) transporter
NX81_015365	COG1253	flavin adenine dinucleotide binding
NX81_015400	COG2850	peptidyl-arginine hydroxylation
NX81_015435	COG1132	(ABC) transporter
NX81_015440	COG0583	DNA-binding transcription factor activity
NX81_015470	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
NX81_015475	COG0484	heat shock protein binding
NX81_015480	COG0443	Heat shock 70 kDa protein
NX81_015485	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NX81_015490	COG1420	regulation of RNA biosynthetic process
NX81_015495	COG0497	DNA recombination
NX81_015505	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NX81_015510	COG2914	Belongs to the UPF0125 (RnfH) family
NX81_015520	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
NX81_015535	COG0582	viral genome integration into host DNA
NX81_015750	COG0305	Participates in initiation and elongation during chromosome replication
NX81_015795	COG3039	Transposase
NX81_015820	COG3706	GGDEF domain
NX81_015830	COG3706	GGDEF domain
NX81_015865	COG0583	DNA-binding transcription factor activity
NX81_015875	COG0415	Belongs to the DNA photolyase family
NX81_015880	COG0305	Participates in initiation and elongation during chromosome replication
NX81_015890	COG0367	asparagine synthase
NX81_015910	COG1960	acyl-CoA dehydrogenase activity
NX81_015930	COG0084	hydrolase, TatD family'
NX81_015935	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
NX81_015995	COG0386	Belongs to the glutathione peroxidase family
NX81_016005	COG0339	signal peptide processing
NX81_016025	COG1595	DNA-templated transcription, initiation
NX81_016080	COG2814	Major facilitator Superfamily
NX81_016085	COG1566	PFAM secretion protein HlyD family protein
NX81_016100	COG2207	Transcriptional regulator
NX81_016115	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NX81_016135	COG4774	siderophore transport
NX81_016145	COG0367	asparagine synthase
NX81_016150	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NX81_016160	COG1393	Belongs to the ArsC family
NX81_016175	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
NX81_016180	COG0024	Methionine aminopeptidase
NX81_016220	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NX81_016225	COG3706	GGDEF domain
NX81_016230	COG0528	UMP kinase activity
NX81_016250	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
NX81_016255	COG0750	zinc metalloprotease
NX81_016265	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NX81_016270	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NX81_016275	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NX81_016280	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NX81_016285	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NX81_016300	COG0825	malonyl-CoA metabolic process
NX81_016360	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
NX81_016370	COG2040	homocysteine
NX81_016375	COG0833	amino acid
NX81_016380	COG0346	lactoylglutathione lyase activity
NX81_016390	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NX81_016390	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NX81_016400	COG2878	Part of a membrane complex involved in electron transport
NX81_016415	COG1595	DNA-templated transcription, initiation
NX81_016440	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
NX81_016455	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
NX81_016460	COG0251	oxidation-reduction process
NX81_016470	COG0392	lysyltransferase activity
NX81_016470	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NX81_016505	COG2814	Major facilitator Superfamily
NX81_016510	COG1902	pentaerythritol trinitrate reductase activity
NX81_016555	COG1047	Peptidyl-prolyl cis-trans
NX81_016590	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
NX81_016600	COG5487	UPF0391 membrane protein
NX81_016610	COG1451	nucleotide metabolic process
NX81_016635	COG0183	Belongs to the thiolase family
NX81_016665	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
NX81_016665	COG1793	dna ligase
NX81_016675	COG1793	dna ligase
NX81_016680	COG1201	RNA secondary structure unwinding
NX81_016695	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NX81_016700	COG1278	Cold shock
NX81_016705	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
NX81_016715	COG1472	Belongs to the glycosyl hydrolase 3 family
NX81_016720	COG3046	protein related to deoxyribodipyrimidine photolyase
NX81_016725	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
NX81_016730	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
NX81_016755	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NX81_016760	COG0571	ribonuclease III activity
NX81_016780	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NX81_016820	COG1024	Enoyl-CoA hydratase
NX81_016825	COG1960	acyl-CoA dehydrogenase activity
NX81_016845	COG3867	Arabinogalactan endo-beta-1,4-galactanase
NX81_016850	COG3250	beta-galactosidase activity
NX81_016875	COG3039	Transposase
NX81_016885	COG1028	Short-chain dehydrogenase reductase Sdr
NX81_016890	COG1028	Short-chain dehydrogenase reductase Sdr
NX81_016900	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NX81_016920	COG0534	Mate efflux family protein
NX81_016930	COG0336	Belongs to the RNA methyltransferase TrmD family
NX81_016935	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NX81_016940	COG0228	four-way junction DNA binding
NX81_016945	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NX81_016950	COG2070	2-Nitropropane dioxygenase
NX81_016960	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NX81_016965	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NX81_016980	COG3039	Transposase
NX81_016995	COG4191	Histidine kinase
NX81_016995	COG0784	Response regulator, receiver
NX81_017000	COG2205	protein histidine kinase activity
NX81_017000	COG3437	response regulator, receiver
NX81_017000	COG3850	Histidine kinase
NX81_017000	COG4999	Histidine kinase
NX81_017005	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
NX81_017015	COG2205	protein histidine kinase activity
NX81_017020	COG5507	3-demethylubiquinone-9 3-methyltransferase
NX81_017055	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
NX81_017060	COG1845	cytochrome c oxidase, subunit III
NX81_017065	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NX81_017080	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NX81_017085	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NX81_017090	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NX81_017095	COG0196	riboflavin kinase activity
NX81_017100	COG0728	peptidoglycan biosynthetic process
NX81_017105	COG0268	Binds directly to 16S ribosomal RNA
NX81_017120	COG0261	This protein binds to 23S rRNA in the presence of protein L20
NX81_017125	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NX81_017130	COG0824	Thioesterase
NX81_017145	COG1946	Acyl-CoA thioesterase
NX81_017170	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NX81_017170	COG4651	solute:proton antiporter activity
NX81_017180	COG4772	TonB-dependent receptor
NX81_017190	COG4264	IucA IucC family
NX81_017195	COG2814	Major facilitator Superfamily
NX81_017205	COG0019	diaminopimelate decarboxylase activity
NX81_017235	COG3039	Transposase
NX81_017245	COG4206	TonB-dependent receptor
NX81_017255	COG0542	response to heat
NX81_017260	COG1116	anion transmembrane transporter activity
NX81_017265	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NX81_017270	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NX81_017275	COG0667	Aldo Keto reductase
NX81_017285	COG4771	TonB-dependent receptor
NX81_017290	COG2827	Endonuclease containing a URI domain
NX81_017380	COG1877	trehalose-phosphatase activity
NX81_017385	COG3387	PFAM Glycoside hydrolase 15-related
NX81_017400	COG0840	transmembrane signaling receptor activity
NX81_017420	COG0564	pseudouridine synthase activity
NX81_017425	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NX81_017430	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
NX81_017430	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NX81_017445	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
NX81_017450	COG0045	succinate-CoA ligase (ADP-forming) activity
NX81_017485	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
NX81_017495	COG3039	Transposase
NX81_017550	COG0745	RESPONSE REGULATOR receiver
NX81_017625	COG2022	thiamine diphosphate biosynthetic process
NX81_017630	COG0220	tRNA (guanine-N7-)-methyltransferase activity
NX81_017635	COG0471	metal ion transport
NX81_017635	COG3273	potassium ion transport
NX81_017655	COG1970	mechanosensitive ion channel activity
NX81_017665	COG1609	Transcriptional regulator
NX81_017690	COG3250	beta-galactosidase activity
NX81_017695	COG4948	Mandelate Racemase Muconate Lactonizing
NX81_017710	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NX81_017720	COG0308	aminopeptidase N
NX81_017770	COG2895	sulfate adenylyltransferase (ATP) activity
NX81_017770	COG0529	Catalyzes the synthesis of activated sulfate
NX81_017780	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NX81_017785	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NX81_017810	COG2205	protein histidine kinase activity
NX81_017810	COG2198	Histidine kinase
NX81_017810	COG0784	Response regulator, receiver
NX81_017830	COG0583	DNA-binding transcription factor activity
NX81_017850	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
NX81_017855	COG3588	fructose-bisphosphate aldolase
NX81_017865	COG0469	pyruvate kinase activity
NX81_017900	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NX81_017920	COG3047	cAMP biosynthetic process
NX81_017930	COG3453	Protein conserved in bacteria
NX81_017930	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NX81_017935	COG0725	ABC transporter, periplasmic molybdate-binding protein
NX81_017940	COG4149	molybdate abc transporter
NX81_017945	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
NX81_017965	COG1376	ErfK ybiS ycfS ynhG family protein
NX81_017970	COG0739	heme binding
NX81_017975	COG1028	Short-chain dehydrogenase reductase Sdr
NX81_017980	COG0583	DNA-binding transcription factor activity
NX81_017985	COG4773	Receptor
NX81_017995	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NX81_018015	COG2304	oxidoreductase activity
NX81_018035	COG0714	Associated with various cellular activities
NX81_018070	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
NX81_018085	COG0254	rRNA binding
NX81_018090	COG1957	nucleoside hydrolase
NX81_018095	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NX81_018105	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NX81_018110	COG1758	RNA polymerase activity
NX81_018120	COG1561	YicC-like family, N-terminal region
NX81_018125	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
NX81_018135	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NX81_018140	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NX81_018155	COG0006	proline dipeptidase activity
NX81_018165	COG0006	proline dipeptidase activity
NX81_018190	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NX81_018210	COG2912	Transglutaminase-like superfamily
NX81_018215	COG1773	rubredoxin
NX81_018220	COG0352	thiamine-phosphate diphosphorylase activity
NX81_018240	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
NX81_018250	COG3039	Transposase
NX81_018260	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
NX81_018265	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NX81_018295	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NX81_018300	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NX81_018310	COG1028	Short-chain dehydrogenase reductase Sdr
NX81_018320	COG0671	phosphoesterase, PA-phosphatase related
NX81_018325	COG3781	membrane
NX81_018335	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
NX81_018355	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
NX81_018365	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
NX81_018385	COG3710	Transcriptional regulator
NX81_018405	COG0840	transmembrane signaling receptor activity
NX81_018415	COG0405	Gamma-glutamyltransferase
NX81_018440	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NX81_018445	COG0473	3-isopropylmalate dehydrogenase activity
NX81_018450	COG2226	methyltransferase
NX81_018455	COG0066	3-isopropylmalate dehydratase activity
NX81_018460	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NX81_018475	COG3706	GGDEF domain
NX81_018485	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
NX81_018490	COG1538	Outer membrane efflux protein
NX81_018495	COG1519	Transferase
NX81_018500	COG1560	Kdo2-lipid A biosynthetic process
NX81_018615	COG0281	malic enzyme
NX81_018615	COG0280	phosphate acetyltransferase
NX81_018620	COG1301	dicarboxylic acid transport
NX81_018630	COG4191	Histidine kinase
NX81_018645	COG0583	DNA-binding transcription factor activity
NX81_018650	COG0667	Aldo Keto reductase
NX81_018670	COG2197	response regulator
NX81_018680	COG0642	Histidine kinase
NX81_018700	COG2851	Citrate transporter
NX81_018705	COG1028	Short-chain dehydrogenase reductase Sdr
NX81_018710	COG1609	Transcriptional regulator
NX81_018715	COG2211	Major facilitator Superfamily
NX81_018740	COG1162	GTPase activity
NX81_018745	COG0436	Aminotransferase
NX81_018765	COG0726	polysaccharide deacetylase
NX81_018770	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
NX81_018785	COG3964	amidohydrolase
NX81_018790	COG0402	S-adenosylhomocysteine deaminase activity
NX81_018850	COG3791	Glutathione-dependent formaldehyde-activating
NX81_018875	COG0745	RESPONSE REGULATOR receiver
NX81_018880	COG2205	protein histidine kinase activity
NX81_018905	COG0218	Necessary for normal cell division and for the maintenance of normal septation
NX81_018920	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NX81_018940	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
NX81_018945	COG0456	acetyltransferase
NX81_018955	COG1183	phosphatidylcholine synthase activity
NX81_018965	COG0442	prolyl-tRNA aminoacylation
NX81_018980	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
NX81_018985	COG1127	ABC transporter
NX81_018990	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
NX81_018990	COG3218	ABC-type transport auxiliary lipoprotein component
NX81_019035	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NX81_019040	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
NX81_019040	COG0662	Cupin 2, conserved barrel domain protein
NX81_019065	COG2086	electron transfer activity
NX81_019080	COG3039	Transposase
NX81_019090	COG0546	phosphoglycolate phosphatase activity
NX81_019090	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
NX81_019095	COG0277	FAD linked oxidase domain protein
NX81_019135	COG0438	transferase activity, transferring glycosyl groups
NX81_019170	COG0626	cystathionine gamma-synthase activity
NX81_019200	COG0625	glutathione transferase activity
NX81_019215	COG0513	Belongs to the DEAD box helicase family
NX81_019225	COG0720	synthase
NX81_019235	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
NX81_019240	COG1956	GAF domain-containing protein
NX81_019255	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NX81_019285	COG0339	signal peptide processing
NX81_019335	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
NX81_019340	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NX81_019345	COG1136	(ABC) transporter
NX81_019350	COG0577	efflux transmembrane transporter activity
NX81_019370	COG4191	Histidine kinase
NX81_019375	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NX81_019415	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NX81_019425	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NX81_019430	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NX81_019440	COG0356	it plays a direct role in the translocation of protons across the membrane
NX81_019460	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NX81_019470	COG0508	dehydrogenase complex catalyzes the overall conversion of
NX81_019520	COG2011	ABC-type metal ion transport system permease component
NX81_019525	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NX81_019535	COG1666	GTP binding
NX81_019545	COG2198	Histidine kinase
NX81_019545	COG5002	protein histidine kinase activity
NX81_019545	COG0784	Response regulator, receiver
NX81_019565	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NX81_019570	COG1187	pseudouridine synthase activity
NX81_019575	COG2813	Specifically methylates the guanine in position
NX81_019605	COG2205	protein histidine kinase activity
NX81_019605	COG2202	Pas domain
NX81_019625	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NX81_019630	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NX81_019635	COG1522	sequence-specific DNA binding
NX81_019675	COG0745	RESPONSE REGULATOR receiver
NX81_019690	COG1404	Belongs to the peptidase S8 family
NX81_019715	COG0842	Transport permease protein
NX81_019720	COG1131	(ABC) transporter
NX81_019725	COG0025	NhaP-type Na H and K H
NX81_019735	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
NX81_019740	COG1573	uracil-dna glycosylase
NX81_019755	COG3384	dioxygenase
NX81_019765	COG0583	DNA-binding transcription factor activity
NX81_019775	COG0667	Aldo Keto reductase
NX81_019785	COG3590	peptidase
NX81_019800	COG0531	amino acid
NX81_019815	COG2972	Histidine kinase
NX81_019840	COG3685	Protein conserved in bacteria
NX81_019845	COG3546	catalase activity
NX81_019895	COG1271	oxidase subunit
NX81_019900	COG1294	oxidase, subunit
NX81_019915	COG1028	Short-chain dehydrogenase reductase Sdr
NX81_019920	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NX81_019940	COG1132	(ABC) transporter
NX81_019955	COG1063	alcohol dehydrogenase
NX81_020055	COG0038	chloride channel
NX81_020065	COG0024	Methionine aminopeptidase
NX81_020095	COG3179	chitinase
NX81_020120	COG0860	N-Acetylmuramoyl-L-alanine amidase
NX81_020165	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NX81_020170	COG1490	D-aminoacyl-tRNA deacylase activity
NX81_020175	COG1560	Kdo2-lipid A biosynthetic process
NX81_020225	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NX81_020225	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NX81_020230	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NX81_020235	COG0242	peptide deformylase activity
NX81_020240	COG1652	LysM domain
NX81_020245	COG0758	DNA mediated transformation
NX81_020265	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NX81_020265	COG1754	DNA topoisomerase type I activity
NX81_020285	COG1028	Short-chain dehydrogenase reductase Sdr
NX81_020295	COG0616	signal peptide processing
NX81_020300	COG0534	Mate efflux family protein
NX81_020320	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NX81_020325	COG0625	glutathione transferase activity
NX81_020340	COG1252	NADH dehydrogenase
NX81_020345	COG2860	membrane
NX81_020350	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NX81_020360	COG3437	response regulator, receiver
NX81_020365	COG2177	Part of the ABC transporter FtsEX involved in
NX81_020370	COG2884	Cell division ATP-binding protein ftsE
NX81_020380	COG3118	belongs to the thioredoxin family
NX81_020385	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NX81_020395	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
NX81_020420	COG1652	LysM domain
NX81_020425	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NX81_020425	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NX81_020440	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NX81_020460	COG5383	Protein conserved in bacteria
NX81_020500	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
NX81_020505	COG3023	N-Acetylmuramoyl-L-alanine amidase
NX81_020515	COG4948	Mandelate Racemase Muconate Lactonizing
NX81_020530	COG0531	amino acid
NX81_020545	COG4682	membrane
NX81_020550	COG2133	pyrroloquinoline quinone binding
NX81_020560	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NX81_020570	COG0828	Belongs to the bacterial ribosomal protein bS21 family
NX81_020575	COG1610	YqeY-like protein
NX81_020580	COG1295	ribonuclease BN
NX81_020585	COG0358	DNA primase activity
NX81_020630	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
NX81_020645	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
NX81_020695	COG0739	heme binding
NX81_020710	COG2211	Major facilitator Superfamily
NX81_020715	COG0708	Exodeoxyribonuclease III
NX81_020730	COG1192	Involved in chromosome partitioning
NX81_020735	COG1475	DNA binding
NX81_020755	COG0463	Glycosyl transferase, family 2
NX81_020780	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NX81_020790	COG0018	arginyl-trna synthetase
NX81_020805	COG4221	oxidoreductase activity
NX81_020825	COG1166	arginine decarboxylase activity
NX81_020830	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
NX81_020870	COG0606	chelatase, subunit chli
NX81_020885	COG4943	cyclic-guanylate-specific phosphodiesterase activity
NX81_020910	COG1690	Belongs to the RtcB family
NX81_020955	COG1090	epimerase
NX81_020965	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NX81_020985	COG0628	permease
NX81_020990	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NX81_020995	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NX81_021010	COG0753	catalase activity
NX81_021025	COG2197	response regulator
NX81_021030	COG3039	Transposase
NX81_021035	COG4585	Histidine kinase
NX81_021040	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NX81_021050	COG1136	(ABC) transporter
NX81_021075	COG0697	spore germination
NX81_021100	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NX81_021105	COG0180	Tryptophanyl-tRNA synthetase
NX81_021110	COG3237	CsbD-like
NX81_021155	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NX81_021175	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
NX81_021175	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
NX81_021205	COG2205	protein histidine kinase activity
NX81_021210	COG0745	RESPONSE REGULATOR receiver
NX81_021220	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NX81_021545	COG1199	ATP-dependent helicase activity
NX81_021560	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NX81_021575	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NX81_021640	COG0625	glutathione transferase activity
NX81_021675	COG4555	ABC transporter
NX81_021690	COG1476	TRANSCRIPTIONal
NX81_021705	COG1230	cation diffusion facilitator family transporter
NX81_021710	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NX81_021715	COG1131	(ABC) transporter
NX81_021720	COG0842	Transport permease protein
NX81_021730	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NX81_021755	COG1607	acyl-coa hydrolase
NX81_021775	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NX81_021780	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NX81_021795	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NX81_021795	COG0045	succinate-CoA ligase (ADP-forming) activity
NX81_021795	COG1042	CoA-binding domain protein
NX81_021810	COG2239	Acts as a magnesium transporter
NX81_021825	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NX81_021830	COG3387	PFAM Glycoside hydrolase 15-related
NX81_021845	COG3100	YcgL domain-containing protein
NX81_021850	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NX81_021860	COG0463	Glycosyl transferase, family 2
NX81_021880	COG1028	Short-chain dehydrogenase reductase Sdr
NX81_021905	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NX81_021920	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NX81_022060	COG0210	DNA helicase
NX81_022075	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NX81_022085	COG2159	amidohydrolase
NX81_022095	COG0267	Belongs to the bacterial ribosomal protein bL33 family
NX81_022100	COG0227	Belongs to the bacterial ribosomal protein bL28 family
NX81_022110	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NX81_022135	COG0357	Ribosomal RNA small subunit methyltransferase G
NX81_022150	COG2091	lysine biosynthetic process via aminoadipic acid
NX81_022165	COG0708	Exodeoxyribonuclease III
NX81_022170	COG1940	carbohydrate kinase activity
NX81_022180	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NX81_022190	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NX81_022195	COG3162	membrane
NX81_022260	COG1028	Short-chain dehydrogenase reductase Sdr
NX81_022265	COG0179	Fumarylacetoacetate (FAA) hydrolase
NX81_022270	COG4948	Mandelate Racemase Muconate Lactonizing
NX81_022275	COG3254	rhamnose metabolic process
NX81_022280	COG0738	Major facilitator superfamily
NX81_022285	COG1414	Transcriptional regulator
NX81_022300	COG2205	protein histidine kinase activity
NX81_022310	COG3459	Glycosyltransferase 36 associated
NX81_022315	COG2211	Major facilitator Superfamily
NX81_022320	COG3265	gluconokinase activity
NX81_022350	COG2911	Protein conserved in bacteria
NX81_022355	COG0729	surface antigen
NX81_022360	COG4771	TonB-dependent receptor
NX81_022365	COG0457	Tetratricopeptide repeat
NX81_022375	COG0752	glycyl-tRNA synthetase alpha subunit
NX81_022380	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NX81_022395	COG0519	Catalyzes the synthesis of GMP from XMP
NX81_022395	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NX81_022405	COG0805	protein transport
NX81_022410	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NX81_022415	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NX81_022425	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
NX81_022445	COG2974	May be involved in recombination
NX81_022450	COG0037	tRNA processing
NX81_022470	COG3661	Belongs to the glycosyl hydrolase 67 family
NX81_022480	COG4948	Mandelate Racemase Muconate Lactonizing
NX81_022490	COG1472	Belongs to the glycosyl hydrolase 3 family
NX81_022495	COG0246	Mannitol dehydrogenase
NX81_022555	COG3386	PFAM SMP-30 Gluconolaconase
NX81_022580	COG1904	glucuronate isomerase
NX81_022585	COG3693	PFAM glycoside hydrolase, family 10
NX81_022605	COG2211	Major facilitator Superfamily
NX81_022645	COG2937	Belongs to the GPAT DAPAT family
NX81_022675	COG0284	orotidine-5'-phosphate decarboxylase activity
NX81_022680	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
NX81_022685	COG3132	Protein of unknown function, DUF480
NX81_022700	COG0210	DNA helicase
NX81_022705	COG1435	thymidine kinase activity
NX81_022715	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
NX81_022725	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
NX81_022755	COG3135	benzoate transporter
NX81_022780	COG0676	glucose-6-phosphate 1-epimerase activity
NX81_022790	COG3012	SEC-C Motif Domain Protein
NX81_022795	COG0730	response to heat
NX81_022815	COG0302	gtp cyclohydrolase
NX81_022830	COG1566	PFAM secretion protein HlyD family protein
NX81_022840	COG1289	transmembrane transporter activity
NX81_022845	COG0477	Major facilitator Superfamily
NX81_022855	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NX81_022900	COG0564	pseudouridine synthase activity
NX81_022920	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NX81_022975	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NX81_022980	COG1074	ATP-dependent DNA helicase activity
NX81_022985	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
NX81_022990	COG1127	ABC transporter
NX81_022995	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
NX81_023000	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
NX81_023015	COG2853	Lipoprotein
NX81_023025	COG0386	Belongs to the glutathione peroxidase family
NX81_023040	COG1322	Protein conserved in bacteria
NX81_023045	COG0604	alcohol dehydrogenase
NX81_023050	COG0583	DNA-binding transcription factor activity
NX81_023075	COG0531	amino acid
NX81_023095	COG2199	diguanylate cyclase activity
NX81_023095	COG2203	Gaf domain
NX81_023100	COG3835	regulator
NX81_023105	COG1929	Belongs to the glycerate kinase type-1 family
NX81_023110	COG2271	Major facilitator Superfamily
NX81_023130	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
NX81_023140	COG0861	Integral membrane protein TerC family
NX81_023150	COG0584	glycerophosphoryl diester phosphodiesterase
NX81_023165	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NX81_023175	COG0706	membrane insertase activity
NX81_023185	COG0230	Belongs to the bacterial ribosomal protein bL34 family
NX81_023190	COG3118	belongs to the thioredoxin family
NX81_023220	COG2172	sigma factor antagonist activity
NX81_023225	COG1366	Belongs to the anti-sigma-factor antagonist family
NX81_023230	COG1366	Belongs to the anti-sigma-factor antagonist family
NX81_023240	COG0326	Molecular chaperone. Has ATPase activity
NX81_023245	COG2207	Transcriptional regulator
NX81_023260	COG3152	Membrane
NX81_023275	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
NX81_023280	COG1845	cytochrome c oxidase, subunit III
NX81_023285	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NX81_023300	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NX81_023305	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NX81_023515	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
NX81_023585	COG3504	Conjugal transfer protein
NX81_023590	COG2948	multi-organism process
NX81_023600	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NX81_023605	COG1845	cytochrome c oxidase, subunit III
NX81_023610	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
NX81_023625	COG3152	Membrane
NX81_023640	COG2207	Transcriptional regulator