locus-tag	class	description
C7V42_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
C7V42_00020	COG0187	DNA topoisomerase II activity
C7V42_00030	COG0501	Belongs to the peptidase M48B family
C7V42_00060	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
C7V42_00070	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C7V42_00100	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C7V42_00105	COG0793	Belongs to the peptidase S41A family
C7V42_00110	COG4942	peptidase
C7V42_00120	COG2234	aminopeptidase activity
C7V42_00130	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
C7V42_00140	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
C7V42_00145	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
C7V42_00155	COG1064	alcohol dehydrogenase
C7V42_00170	COG0493	'glutamate synthase
C7V42_00175	COG0067	glutamate synthase
C7V42_00175	COG0070	glutamate synthase
C7V42_00175	COG0069	glutamate synthase activity
C7V42_00255	COG1205	dead DEAH box helicase
C7V42_00255	COG1111	helicase
C7V42_00260	COG1272	protein, Hemolysin III
C7V42_00300	COG2249	NAD(P)H dehydrogenase (quinone) activity
C7V42_00330	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7V42_00335	COG0477	Major facilitator Superfamily
C7V42_00370	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
C7V42_00390	COG3039	Transposase
C7V42_00400	COG4772	TonB-dependent receptor
C7V42_00425	COG1304	FMN binding
C7V42_00455	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
C7V42_00485	COG2831	hemolysin activation secretion protein
C7V42_00490	COG3210	domain, Protein
C7V42_00520	COG3210	domain, Protein
C7V42_00540	COG3210	domain, Protein
C7V42_00555	COG0366	Alpha amylase catalytic
C7V42_00560	COG0366	Alpha amylase catalytic
C7V42_00585	COG0657	acetylesterase activity
C7V42_00585	COG2755	lipolytic protein G-D-S-L family
C7V42_00595	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
C7V42_00610	COG3507	Belongs to the glycosyl hydrolase 43 family
C7V42_00615	COG1609	Transcriptional regulator
C7V42_00620	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
C7V42_00625	COG1028	Short-chain dehydrogenase reductase Sdr
C7V42_00635	COG2755	lipolytic protein G-D-S-L family
C7V42_00645	COG3186	Phenylalanine-4-hydroxylase
C7V42_00650	COG1522	sequence-specific DNA binding
C7V42_00665	COG2951	lytic endotransglycosylase activity
C7V42_00670	COG1752	Esterase of the alpha-beta hydrolase superfamily
C7V42_00675	COG1473	amidohydrolase
C7V42_00685	COG1119	ATPase activity
C7V42_00700	COG1125	glycine betaine transport
C7V42_00700	COG0517	IMP dehydrogenase activity
C7V42_00715	COG1262	PFAM Formylglycine-generating sulfatase enzyme
C7V42_00720	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
C7V42_00730	COG1262	PFAM Formylglycine-generating sulfatase enzyme
C7V42_00735	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
C7V42_00765	COG0489	protein tyrosine kinase activity
C7V42_00770	COG2062	phosphohistidine phosphatase, SixA
C7V42_00780	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C7V42_00835	COG0174	glutamine synthetase
C7V42_00840	COG0347	Belongs to the P(II) protein family
C7V42_00845	COG0004	ammonium transporteR
C7V42_00850	COG3852	Histidine kinase
C7V42_00855	COG2204	response regulator
C7V42_00860	COG2032	superoxide dismutase activity
C7V42_00865	COG2032	superoxide dismutase activity
C7V42_00875	COG0346	lactoylglutathione lyase activity
C7V42_00885	COG0183	Belongs to the thiolase family
C7V42_00925	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C7V42_00930	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
C7V42_00935	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
C7V42_00945	COG0028	Belongs to the TPP enzyme family
C7V42_00950	COG2205	protein histidine kinase activity
C7V42_00975	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
C7V42_00990	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C7V42_00995	COG3177	Filamentation induced by cAMP protein fic
C7V42_01010	COG0596	Alpha beta hydrolase
C7V42_01020	COG0318	PFAM AMP-dependent synthetase and ligase
C7V42_01025	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C7V42_01045	COG1181	Belongs to the D-alanine--D-alanine ligase family
C7V42_01065	COG0564	pseudouridine synthase activity
C7V42_01085	COG1446	asparaginase
C7V42_01090	COG0339	signal peptide processing
C7V42_01120	COG0475	glutathione-regulated potassium exporter activity
C7V42_01125	COG0583	DNA-binding transcription factor activity
C7V42_01130	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
C7V42_01135	COG2224	Isocitrate lyase
C7V42_01140	COG3706	GGDEF domain
C7V42_01170	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
C7V42_01175	COG1960	acyl-CoA dehydrogenase activity
C7V42_01230	COG0523	cobalamin synthesis protein
C7V42_01240	COG0697	spore germination
C7V42_01250	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
C7V42_01265	COG1846	Transcriptional regulator
C7V42_01270	COG1764	response to oxidative stress
C7V42_01295	COG2130	NADP-dependent
C7V42_01310	COG1187	pseudouridine synthase activity
C7V42_01320	COG1643	Atp-dependent helicase
C7V42_01325	COG4807	Protein conserved in bacteria
C7V42_01330	COG2351	hydroxyisourate hydrolase activity
C7V42_01335	COG2072	flavoprotein involved in K transport
C7V42_01355	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
C7V42_01450	COG2252	PERMEase
C7V42_01470	COG0084	hydrolase, TatD family'
C7V42_01510	COG0583	DNA-binding transcription factor activity
C7V42_01520	COG4221	oxidoreductase activity
C7V42_01530	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
C7V42_01535	COG1902	pentaerythritol trinitrate reductase activity
C7V42_01560	COG0745	RESPONSE REGULATOR receiver
C7V42_01580	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
C7V42_01585	COG0583	DNA-binding transcription factor activity
C7V42_01620	COG0702	epimerase
C7V42_01625	COG1733	regulation of RNA biosynthetic process
C7V42_01695	COG0129	dihydroxy-acid dehydratase activity
C7V42_01710	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
C7V42_01770	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
C7V42_01775	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
C7V42_01800	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
C7V42_01805	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
C7V42_01815	COG3485	protocatechuate 3,4-dioxygenase
C7V42_01820	COG3485	protocatechuate 3,4-dioxygenase
C7V42_01830	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
C7V42_01835	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C7V42_01840	COG1414	Transcriptional regulator
C7V42_01855	COG0445	tRNA wobble uridine modification
C7V42_01870	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
C7V42_01915	COG0156	8-amino-7-oxononanoate synthase activity
C7V42_01920	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
C7V42_01925	COG1040	competence protein
C7V42_01960	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
C7V42_02050	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
C7V42_02120	COG3264	Mechanosensitive ion channel
C7V42_02120	COG1511	domain protein
C7V42_02125	COG1368	sulfuric ester hydrolase activity
C7V42_02135	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
C7V42_02140	COG2354	Protein conserved in bacteria
C7V42_02150	COG0745	RESPONSE REGULATOR receiver
C7V42_02150	COG3706	GGDEF domain
C7V42_02155	COG0297	glycogen (starch) synthase activity
C7V42_02160	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
C7V42_02165	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
C7V42_02190	COG0702	epimerase
C7V42_02195	COG3039	Transposase
C7V42_02200	COG1028	Short-chain dehydrogenase reductase Sdr
C7V42_02225	COG0513	Belongs to the DEAD box helicase family
C7V42_02240	COG0508	dehydrogenase complex catalyzes the overall conversion of
C7V42_02255	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
C7V42_02275	COG3104	oligopeptide transport
C7V42_02295	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
C7V42_02370	COG1320	monovalent cation:proton antiporter activity
C7V42_02375	COG2212	antiporter activity
C7V42_02385	COG0651	ATP synthesis coupled electron transport
C7V42_02390	COG1006	Multisubunit Na H antiporter MnhC subunit
C7V42_02395	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
C7V42_02395	COG2111	Na H antiporter
C7V42_02450	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
C7V42_02455	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
C7V42_02465	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
C7V42_02470	COG0456	acetyltransferase
C7V42_02475	COG1597	lipid kinase activity
C7V42_02505	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
C7V42_02510	COG0134	indole-3-glycerol-phosphate synthase activity
C7V42_02520	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C7V42_02540	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
C7V42_02580	COG0745	RESPONSE REGULATOR receiver
C7V42_02600	COG0316	Belongs to the HesB IscA family
C7V42_02615	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
C7V42_02635	COG2814	Major facilitator Superfamily
C7V42_02645	COG2814	Major facilitator Superfamily
C7V42_02650	COG1289	transmembrane transporter activity
C7V42_02655	COG0151	Belongs to the GarS family
C7V42_02665	COG0419	ATPase involved in DNA repair
C7V42_02670	COG0138	bifunctional purine biosynthesis protein purh
C7V42_02675	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
C7V42_02695	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
C7V42_02745	COG0439	Biotin carboxylase
C7V42_02755	COG0511	ligase activity, forming carbon-carbon bonds
C7V42_02760	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
C7V42_02770	COG1324	tolerance protein
C7V42_02790	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
C7V42_02815	COG4771	TonB-dependent receptor
C7V42_02820	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
C7V42_02835	COG3386	PFAM SMP-30 Gluconolaconase
C7V42_02845	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
C7V42_02890	COG0778	Nitroreductase
C7V42_02895	COG2353	YceI-like domain
C7V42_02935	COG3052	prosthetic group binding
C7V42_02970	COG1802	Transcriptional regulator
C7V42_03020	COG2176	DNA-directed DNA polymerase activity
C7V42_03120	COG4221	oxidoreductase activity
C7V42_03125	COG0435	Glutathione S-transferase
C7V42_03190	COG0697	spore germination
C7V42_03205	COG4305	rare lipoprotein A
C7V42_03215	COG1113	amino acid transport
C7V42_03225	COG0598	Magnesium transport protein CorA
C7V42_03280	COG0840	transmembrane signaling receptor activity
C7V42_03285	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
C7V42_03285	COG5297	Belongs to the glycosyl hydrolase family 6
C7V42_03290	COG0659	secondary active sulfate transmembrane transporter activity
C7V42_03315	COG2943	transferase activity, transferring hexosyl groups
C7V42_03325	COG3275	phosphorelay sensor kinase activity
C7V42_03335	COG0181	hydroxymethylbilane synthase activity
C7V42_03365	COG1505	serine-type exopeptidase activity
C7V42_03390	COG2832	Protein of unknown function (DUF454)
C7V42_03400	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
C7V42_03410	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
C7V42_03420	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
C7V42_03425	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
C7V42_03450	COG2226	methyltransferase
C7V42_03460	COG5001	Diguanylate cyclase
C7V42_03460	COG3300	MHYT domain
C7V42_03465	COG0308	aminopeptidase N
C7V42_03500	COG0730	response to heat
C7V42_03505	COG1012	belongs to the aldehyde dehydrogenase family
C7V42_03510	COG0367	asparagine synthase
C7V42_03525	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
C7V42_03525	COG0028	Belongs to the TPP enzyme family
C7V42_03550	COG1077	Cell shape determining protein MreB Mrl
C7V42_03555	COG1792	Involved in formation and maintenance of cell shape
C7V42_03570	COG0772	Belongs to the SEDS family
C7V42_03585	COG5297	Belongs to the glycosyl hydrolase family 6
C7V42_03630	COG2951	lytic endotransglycosylase activity
C7V42_03635	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
C7V42_03640	COG1686	Belongs to the peptidase S11 family
C7V42_03655	COG0321	lipoyl(octanoyl) transferase activity
C7V42_03660	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
C7V42_03675	COG1051	belongs to the nudix hydrolase family
C7V42_03675	COG1056	cytidyltransferase-related domain
C7V42_03710	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
C7V42_03715	COG0673	inositol 2-dehydrogenase activity
C7V42_03720	COG2823	Periplasmic or secreted lipoprotein
C7V42_03725	COG4251	negative regulation of phosphorylation
C7V42_03730	COG0784	Response regulator, receiver
C7V42_03735	COG4191	Histidine kinase
C7V42_03740	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
C7V42_03745	COG1028	Short-chain dehydrogenase reductase Sdr
C7V42_03775	COG3250	beta-galactosidase activity
C7V42_03800	COG1609	Transcriptional regulator
C7V42_03805	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
C7V42_03810	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
C7V42_03825	COG1215	transferase activity, transferring glycosyl groups
C7V42_03830	COG1649	PFAM Uncharacterised BCR, COG1649
C7V42_03830	COG0726	polysaccharide deacetylase
C7V42_03855	COG4206	TonB-dependent receptor
C7V42_03890	COG0525	valine-tRNA ligase activity
C7V42_03905	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
C7V42_03915	COG0795	lipopolysaccharide-transporting ATPase activity
C7V42_03925	COG4974	Belongs to the 'phage' integrase family
C7V42_03930	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C7V42_03940	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
C7V42_03940	COG0047	phosphoribosylformylglycinamidine synthase activity
C7V42_03950	COG5295	Hep Hag repeat protein
C7V42_03960	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C7V42_03970	COG1459	type II secretion system
C7V42_03975	COG2165	general secretion pathway protein
C7V42_03980	COG4970	Tfp pilus assembly protein FimT
C7V42_03985	COG2165	general secretion pathway protein
C7V42_03990	COG4795	General secretion pathway protein
C7V42_03995	COG3156	type II secretion system protein K
C7V42_04000	COG3166	PFAM Fimbrial assembly family protein
C7V42_04015	COG1450	Type ii and iii secretion system protein
C7V42_04025	COG2188	Transcriptional regulator
C7V42_04075	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
C7V42_04105	COG0242	peptide deformylase activity
C7V42_04110	COG0488	(ABC) transporter
C7V42_04135	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
C7V42_04140	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
C7V42_04150	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C7V42_04150	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C7V42_04170	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
C7V42_04180	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
C7V42_04225	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
C7V42_04230	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
C7V42_04240	COG2205	protein histidine kinase activity
C7V42_04245	COG0745	RESPONSE REGULATOR receiver
C7V42_04250	COG0277	FAD linked oxidase domain protein
C7V42_04255	COG1988	membrane-bound metal-dependent
C7V42_04305	COG0275	rRNA processing
C7V42_04310	COG3116	cell division
C7V42_04325	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
C7V42_04330	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C7V42_04340	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
C7V42_04345	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
C7V42_04350	COG1181	Belongs to the D-alanine--D-alanine ligase family
C7V42_04355	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
C7V42_04370	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
C7V42_04380	COG0739	heme binding
C7V42_04385	COG0653	protein targeting
C7V42_04390	COG0494	nUDIX hydrolase
C7V42_04405	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
C7V42_04415	COG0604	alcohol dehydrogenase
C7V42_04415	COG1028	Short-chain dehydrogenase reductase Sdr
C7V42_04415	COG3321	synthase
C7V42_04465	COG2226	methyltransferase
C7V42_04480	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
C7V42_04515	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
C7V42_04530	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C7V42_04545	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C7V42_04550	COG0667	Aldo Keto reductase
C7V42_04565	COG4771	TonB-dependent receptor
C7V42_04585	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C7V42_04590	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
C7V42_04600	COG2175	clavaminate synthase activity
C7V42_04610	COG4181	ATPase activity
C7V42_04625	COG0642	Histidine kinase
C7V42_04640	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
C7V42_04660	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
C7V42_04675	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
C7V42_04680	COG2967	ApaG domain
C7V42_04685	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
C7V42_04695	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
C7V42_04705	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
C7V42_04710	COG0123	including yeast histone deacetylase and acetoin utilization protein
C7V42_04715	COG2096	Adenosyltransferase
C7V42_04730	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C7V42_04735	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C7V42_04760	COG3384	dioxygenase
C7V42_04765	COG0583	DNA-binding transcription factor activity
C7V42_04770	COG0318	PFAM AMP-dependent synthetase and ligase
C7V42_04780	COG1024	Enoyl-CoA hydratase
C7V42_04800	COG3386	PFAM SMP-30 Gluconolaconase
C7V42_04825	COG0697	spore germination
C7V42_04835	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
C7V42_04850	COG3706	GGDEF domain
C7V42_04850	COG0745	RESPONSE REGULATOR receiver
C7V42_04860	COG3039	Transposase
C7V42_04870	COG2197	response regulator
C7V42_04880	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C7V42_04890	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
C7V42_04895	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C7V42_04900	COG0583	DNA-binding transcription factor activity
C7V42_04905	COG3634	alkyl hydroperoxide reductase activity
C7V42_04915	COG2890	protein-(glutamine-N5) methyltransferase activity
C7V42_04960	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C7V42_04960	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C7V42_04980	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
C7V42_05005	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
C7V42_05025	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C7V42_05030	COG1404	Belongs to the peptidase S8 family
C7V42_05035	COG1404	Belongs to the peptidase S8 family
C7V42_05040	COG1404	Belongs to the peptidase S8 family
C7V42_05045	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
C7V42_05070	COG1295	ribonuclease BN
C7V42_05075	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7V42_05095	COG0521	Mo-molybdopterin cofactor biosynthetic process
C7V42_05110	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
C7V42_05120	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
C7V42_05125	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
C7V42_05135	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
C7V42_05140	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
C7V42_05145	COG0193	aminoacyl-tRNA hydrolase activity
C7V42_05150	COG0012	GTP binding
C7V42_05170	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
C7V42_05180	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C7V42_05185	COG0250	Participates in transcription elongation, termination and antitermination
C7V42_05190	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
C7V42_05195	COG0081	regulation of translation
C7V42_05200	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
C7V42_05210	COG0085	RNA polymerase activity
C7V42_05220	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
C7V42_05225	COG0049	tRNA binding
C7V42_05230	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
C7V42_05235	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
C7V42_05255	COG0051	transcription antitermination factor activity, RNA binding
C7V42_05265	COG0088	Forms part of the polypeptide exit tunnel
C7V42_05275	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
C7V42_05295	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
C7V42_05300	COG0255	Belongs to the universal ribosomal protein uL29 family
C7V42_05305	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
C7V42_05310	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
C7V42_05315	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
C7V42_05325	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
C7V42_05345	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
C7V42_05350	COG1841	ribosomal large subunit assembly
C7V42_05355	COG0200	Binds to the 23S rRNA
C7V42_05360	COG0201	protein transport
C7V42_05365	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
C7V42_05370	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
C7V42_05375	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
C7V42_05380	COG0202	RNA polymerase activity
C7V42_05385	COG0203	ribosomal protein L17
C7V42_05390	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
C7V42_05405	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
C7V42_05440	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
C7V42_05450	COG0625	glutathione transferase activity
C7V42_05470	COG1902	pentaerythritol trinitrate reductase activity
C7V42_05470	COG0446	pyridine nucleotide-disulphide oxidoreductase
C7V42_05475	COG0604	alcohol dehydrogenase
C7V42_05480	COG2885	chlorophyll binding
C7V42_05500	COG0156	8-amino-7-oxononanoate synthase activity
C7V42_05505	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
C7V42_05510	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
C7V42_05515	COG4208	sulfate ABC transporter
C7V42_05520	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
C7V42_05550	COG0406	alpha-ribazole phosphatase activity
C7V42_05560	COG0285	dihydrofolate synthase activity
C7V42_05580	COG2833	Protein of unknown function (DUF455)
C7V42_05585	COG3291	Pkd domain containing protein
C7V42_05595	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
C7V42_05600	COG0671	phosphoesterase, PA-phosphatase related
C7V42_05605	COG0438	transferase activity, transferring glycosyl groups
C7V42_05620	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
C7V42_05635	COG4783	chaperone-mediated protein folding
C7V42_05655	COG0473	3-isopropylmalate dehydrogenase activity
C7V42_05695	COG0544	peptidyl-prolyl cis-trans isomerase activity
C7V42_05700	COG0740	serine-type endopeptidase activity
C7V42_05705	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
C7V42_05735	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C7V42_05745	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7V42_05760	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C7V42_05770	COG0631	protein serine/threonine phosphatase activity
C7V42_05785	COG0859	PFAM glycosyl transferase family 9
C7V42_05790	COG3642	lipopolysaccharide core region biosynthetic process
C7V42_05795	COG1234	tRNA 3'-trailer cleavage
C7V42_05800	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
C7V42_05815	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
C7V42_05820	COG0314	molybdopterin synthase activity
C7V42_05860	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
C7V42_05870	COG0537	adenosine 5'-monophosphoramidase activity
C7V42_05890	COG0714	Associated with various cellular activities
C7V42_05910	COG1399	metal-binding, possibly nucleic acid-binding protein
C7V42_05920	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C7V42_05935	COG1028	Short-chain dehydrogenase reductase Sdr
C7V42_05950	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C7V42_05955	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
C7V42_05975	COG4115	mRNA cleavage
C7V42_05980	COG2161	toxin-antitoxin pair type II binding
C7V42_05990	COG3829	transcription factor binding
C7V42_06010	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
C7V42_06060	COG4953	penicillin-binding protein 1C
C7V42_06070	COG0678	peroxiredoxin activity
C7V42_06090	COG0330	HflC and HflK could
C7V42_06095	COG0330	HflC and HflK could
C7V42_06100	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
C7V42_06105	COG0308	aminopeptidase N
C7V42_06145	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
C7V42_06195	COG0406	alpha-ribazole phosphatase activity
C7V42_06195	COG0328	RNA-DNA hybrid ribonuclease activity
C7V42_06200	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
C7V42_06210	COG3387	PFAM Glycoside hydrolase 15-related
C7V42_06215	COG1028	Short-chain dehydrogenase reductase Sdr
C7V42_06230	COG3039	Transposase
C7V42_06255	COG3293	Transposase
C7V42_06260	COG3537	Alpha-1,2-mannosidase
C7V42_06265	COG4221	oxidoreductase activity
C7V42_06275	COG0492	ferredoxin-NADP+ reductase activity
C7V42_06285	COG2199	diguanylate cyclase activity
C7V42_06285	COG3287	FIST C domain
C7V42_06285	COG2200	EAL domain
C7V42_06320	COG3039	Transposase
C7V42_06330	COG1529	Aldehyde oxidase and xanthine dehydrogenase
C7V42_06335	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
C7V42_06340	COG2080	2 iron, 2 sulfur cluster binding
C7V42_06375	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
C7V42_06390	COG0587	DNA-directed DNA polymerase activity
C7V42_06425	COG1297	OPT oligopeptide transporter protein
C7V42_06445	COG1506	peptidase
C7V42_06445	COG0823	Involved in the tonB-independent uptake of proteins
C7V42_06475	COG1917	Cupin 2, conserved barrel domain protein
C7V42_06475	COG2207	Transcriptional regulator
C7V42_06540	COG0753	catalase activity
C7V42_06545	COG0656	L-ascorbic acid biosynthetic process
C7V42_06560	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
C7V42_06560	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
C7V42_06580	COG2814	Major facilitator Superfamily
C7V42_06595	COG2194	sulfuric ester hydrolase activity
C7V42_06610	COG0745	RESPONSE REGULATOR receiver
C7V42_06615	COG0642	Histidine kinase
C7V42_06625	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
C7V42_06630	COG2894	cell division
C7V42_06635	COG0850	regulation of cytokinetic process
C7V42_06645	COG4585	Histidine kinase
C7V42_06650	COG2197	response regulator
C7V42_06665	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
C7V42_06710	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
C7V42_06740	COG1946	Acyl-CoA thioesterase
C7V42_06755	COG0824	Thioesterase
C7V42_06760	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
C7V42_06765	COG0261	This protein binds to 23S rRNA in the presence of protein L20
C7V42_06780	COG0268	Binds directly to 16S ribosomal RNA
C7V42_06785	COG0728	peptidoglycan biosynthetic process
C7V42_06790	COG0196	riboflavin kinase activity
C7V42_06795	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
C7V42_06800	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
C7V42_06805	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
C7V42_06820	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
C7V42_06825	COG1845	cytochrome c oxidase, subunit III
C7V42_06830	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
C7V42_06845	COG3152	Membrane
C7V42_06860	COG2207	Transcriptional regulator
C7V42_06865	COG0326	Molecular chaperone. Has ATPase activity
C7V42_06875	COG1366	Belongs to the anti-sigma-factor antagonist family
C7V42_06880	COG1366	Belongs to the anti-sigma-factor antagonist family
C7V42_06885	COG2172	sigma factor antagonist activity
C7V42_06920	COG5507	3-demethylubiquinone-9 3-methyltransferase
C7V42_06925	COG2205	protein histidine kinase activity
C7V42_06935	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
C7V42_06940	COG3437	response regulator, receiver
C7V42_06940	COG3850	Histidine kinase
C7V42_06940	COG2205	protein histidine kinase activity
C7V42_06940	COG4999	Histidine kinase
C7V42_06945	COG4191	Histidine kinase
C7V42_06945	COG0784	Response regulator, receiver
C7V42_06965	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C7V42_06970	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
C7V42_06980	COG2070	2-Nitropropane dioxygenase
C7V42_06985	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C7V42_06990	COG0228	four-way junction DNA binding
C7V42_06995	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
C7V42_07000	COG0336	Belongs to the RNA methyltransferase TrmD family
C7V42_07010	COG0534	Mate efflux family protein
C7V42_07020	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
C7V42_07030	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
C7V42_07040	COG1028	Short-chain dehydrogenase reductase Sdr
C7V42_07045	COG1028	Short-chain dehydrogenase reductase Sdr
C7V42_07050	COG1028	Short-chain dehydrogenase reductase Sdr
C7V42_07065	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
C7V42_07080	COG3250	beta-galactosidase activity
C7V42_07085	COG3867	Arabinogalactan endo-beta-1,4-galactanase
C7V42_07105	COG1960	acyl-CoA dehydrogenase activity
C7V42_07110	COG1024	Enoyl-CoA hydratase
C7V42_07155	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C7V42_07175	COG0571	ribonuclease III activity
C7V42_07180	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
C7V42_07210	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
C7V42_07215	COG3046	protein related to deoxyribodipyrimidine photolyase
C7V42_07220	COG1472	Belongs to the glycosyl hydrolase 3 family
C7V42_07230	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
C7V42_07235	COG1278	Cold shock
C7V42_07240	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C7V42_07255	COG1201	RNA secondary structure unwinding
C7V42_07260	COG1793	dna ligase
C7V42_07270	COG1793	dna ligase
C7V42_07270	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
C7V42_07305	COG0183	Belongs to the thiolase family
C7V42_07330	COG1451	nucleotide metabolic process
C7V42_07340	COG5487	UPF0391 membrane protein
C7V42_07350	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C7V42_07385	COG1047	Peptidyl-prolyl cis-trans
C7V42_07400	COG2824	Alkylphosphonate utilization operon protein PhnA
C7V42_07415	COG1902	pentaerythritol trinitrate reductase activity
C7V42_07420	COG2814	Major facilitator Superfamily
C7V42_07455	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
C7V42_07455	COG0392	lysyltransferase activity
C7V42_07465	COG0251	oxidation-reduction process
C7V42_07470	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
C7V42_07485	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
C7V42_07510	COG1595	DNA-templated transcription, initiation
C7V42_07530	COG2878	Part of a membrane complex involved in electron transport
C7V42_07540	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C7V42_07540	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C7V42_07550	COG0346	lactoylglutathione lyase activity
C7V42_07555	COG0833	amino acid
C7V42_07560	COG2040	homocysteine
C7V42_07570	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
C7V42_07635	COG0825	malonyl-CoA metabolic process
C7V42_07650	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
C7V42_07655	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
C7V42_07660	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
C7V42_07665	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
C7V42_07670	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
C7V42_07685	COG0750	zinc metalloprotease
C7V42_07690	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
C7V42_07710	COG0528	UMP kinase activity
C7V42_07715	COG3706	GGDEF domain
C7V42_07720	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
C7V42_07760	COG0024	Methionine aminopeptidase
C7V42_07765	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
C7V42_07780	COG1393	Belongs to the ArsC family
C7V42_07790	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C7V42_07795	COG0367	asparagine synthase
C7V42_07805	COG4774	siderophore transport
C7V42_07825	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C7V42_07855	COG1566	PFAM secretion protein HlyD family protein
C7V42_07860	COG2814	Major facilitator Superfamily
C7V42_07945	COG0339	signal peptide processing
C7V42_07955	COG0386	Belongs to the glutathione peroxidase family
C7V42_08015	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
C7V42_08020	COG0084	hydrolase, TatD family'
C7V42_08035	COG1960	acyl-CoA dehydrogenase activity
C7V42_08055	COG0367	asparagine synthase
C7V42_08065	COG0305	Participates in initiation and elongation during chromosome replication
C7V42_08070	COG0415	Belongs to the DNA photolyase family
C7V42_08085	COG0583	DNA-binding transcription factor activity
C7V42_08120	COG3706	GGDEF domain
C7V42_08130	COG3706	GGDEF domain
C7V42_08170	COG0582	viral genome integration into host DNA
C7V42_08185	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
C7V42_08195	COG2914	Belongs to the UPF0125 (RnfH) family
C7V42_08205	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C7V42_08215	COG0497	DNA recombination
C7V42_08220	COG1420	regulation of RNA biosynthetic process
C7V42_08225	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
C7V42_08230	COG0443	Heat shock 70 kDa protein
C7V42_08235	COG0484	heat shock protein binding
C7V42_08240	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
C7V42_08270	COG0583	DNA-binding transcription factor activity
C7V42_08280	COG1132	(ABC) transporter
C7V42_08315	COG2850	peptidyl-arginine hydroxylation
C7V42_08345	COG1253	flavin adenine dinucleotide binding
C7V42_08375	COG1131	(ABC) transporter
C7V42_08380	COG1725	Transcriptional regulator
C7V42_08390	COG0386	Belongs to the glutathione peroxidase family
C7V42_08430	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C7V42_08445	COG1410	methionine synthase
C7V42_08445	COG0646	methionine synthase
C7V42_08455	COG1960	acyl-CoA dehydrogenase activity
C7V42_08475	COG0557	exoribonuclease II activity
C7V42_08485	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C7V42_08490	COG3706	GGDEF domain
C7V42_08495	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C7V42_08505	COG0704	Plays a role in the regulation of phosphate uptake
C7V42_08510	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C7V42_08515	COG0581	inorganic phosphate transmembrane transporter activity
C7V42_08520	COG0573	inorganic phosphate transmembrane transporter activity
C7V42_08525	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
C7V42_08555	COG0659	secondary active sulfate transmembrane transporter activity
C7V42_08560	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
C7V42_08570	COG1024	Enoyl-CoA hydratase
C7V42_08580	COG0494	nUDIX hydrolase
C7V42_08625	COG0116	Belongs to the methyltransferase superfamily
C7V42_08625	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
C7V42_08630	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
C7V42_08645	COG0667	Aldo Keto reductase
C7V42_08655	COG2925	Exonuclease
C7V42_08660	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C7V42_08665	COG3844	kynureninase activity
C7V42_08680	COG0288	reversible hydration of carbon dioxide
C7V42_08685	COG2808	Putative FMN-binding domain
C7V42_08705	COG0017	Asparaginyl-tRNA synthetase
C7V42_08710	COG0316	Belongs to the HesB IscA family
C7V42_08735	COG3115	cell septum assembly
C7V42_08745	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
C7V42_08750	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
C7V42_08755	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
C7V42_08765	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
C7V42_08800	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
C7V42_08810	COG2986	histidine ammonia-lyase
C7V42_08825	COG3039	Transposase
C7V42_08855	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
C7V42_08860	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
C7V42_08865	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
C7V42_08870	COG0077	Prephenate dehydratase
C7V42_08870	COG1605	Chorismate mutase
C7V42_08875	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
C7V42_08890	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
C7V42_08895	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
C7V42_08900	COG0583	DNA-binding transcription factor activity
C7V42_08945	COG0840	transmembrane signaling receptor activity
C7V42_08965	COG2205	protein histidine kinase activity
C7V42_08965	COG5002	protein histidine kinase activity
C7V42_08965	COG0784	Response regulator, receiver
C7V42_08970	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
C7V42_08975	COG4191	Histidine kinase
C7V42_08975	COG0784	Response regulator, receiver
C7V42_08990	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7V42_09000	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
C7V42_09010	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C7V42_09080	COG2244	polysaccharide biosynthetic process
C7V42_09105	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
C7V42_09120	COG0438	transferase activity, transferring glycosyl groups
C7V42_09135	COG1136	(ABC) transporter
C7V42_09140	COG1132	(ABC) transporter
C7V42_09145	COG0477	Major facilitator Superfamily
C7V42_09155	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C7V42_09170	COG1253	flavin adenine dinucleotide binding
C7V42_09185	COG0306	phosphate transporter
C7V42_09190	COG1434	Gram-negative-bacterium-type cell wall biogenesis
C7V42_09200	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
C7V42_09205	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
C7V42_09210	COG0291	Belongs to the bacterial ribosomal protein bL35 family
C7V42_09215	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
C7V42_09220	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
C7V42_09230	COG0776	regulation of translation
C7V42_09275	COG0438	transferase activity, transferring glycosyl groups
C7V42_09280	COG0438	transferase activity, transferring glycosyl groups
C7V42_09315	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C7V42_09320	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7V42_09325	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C7V42_09345	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
C7V42_09355	COG1960	acyl-CoA dehydrogenase activity
C7V42_09365	COG3040	lipid binding
C7V42_09390	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
C7V42_09395	COG0784	Response regulator, receiver
C7V42_09395	COG4191	Histidine kinase
C7V42_09415	COG0552	protein localization to endoplasmic reticulum
C7V42_09425	COG3938	Belongs to the proline racemase family
C7V42_09430	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C7V42_09445	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C7V42_09455	COG0006	proline dipeptidase activity
C7V42_09470	COG0531	amino acid
C7V42_09570	COG0326	Molecular chaperone. Has ATPase activity
C7V42_09575	COG0742	ribosomal rna small subunit methyltransferase
C7V42_09580	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
C7V42_09595	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
C7V42_09600	COG0405	Gamma-glutamyltransferase
C7V42_09615	COG3291	Pkd domain containing protein
C7V42_09620	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
C7V42_09660	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
C7V42_09665	COG0343	queuine tRNA-ribosyltransferase activity
C7V42_09670	COG1862	Preprotein translocase
C7V42_09680	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C7V42_09725	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7V42_09725	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7V42_09730	COG1105	Belongs to the carbohydrate kinase PfkB family
C7V42_09735	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7V42_09735	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C7V42_09740	COG1609	Transcriptional regulator
C7V42_09775	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C7V42_09780	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C7V42_09790	COG2902	Dehydrogenase
C7V42_09795	COG0477	Major facilitator Superfamily
C7V42_09810	COG5002	protein histidine kinase activity
C7V42_09810	COG2205	protein histidine kinase activity
C7V42_09810	COG0784	Response regulator, receiver
C7V42_09815	COG2733	membrane
C7V42_09825	COG1121	(ABC) transporter
C7V42_09840	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
C7V42_09845	COG0243	molybdopterin cofactor binding
C7V42_09860	COG0477	Major facilitator Superfamily
C7V42_09865	COG3706	GGDEF domain
C7V42_09865	COG0745	RESPONSE REGULATOR receiver
C7V42_09870	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C7V42_09875	COG0174	glutamine synthetase
C7V42_09880	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
C7V42_09895	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
C7V42_09915	COG3842	ATPase activity
C7V42_09920	COG1176	ABC-type spermidine putrescine transport system, permease component I
C7V42_09925	COG1177	transmembrane transport
C7V42_09930	COG1012	belongs to the aldehyde dehydrogenase family
C7V42_09945	COG4535	Mg2 and Co2 transporter CorC
C7V42_09970	COG1702	phosphate starvation-inducible protein PhoH
C7V42_09990	COG0741	lytic transglycosylase activity
C7V42_09995	COG0723	plastoquinol--plastocyanin reductase activity
C7V42_10000	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
C7V42_10005	COG2857	Cytochrome c1
C7V42_10010	COG0625	glutathione transferase activity
C7V42_10015	COG2969	positive regulation of protein catabolic process
C7V42_10035	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
C7V42_10040	COG1201	RNA secondary structure unwinding
C7V42_10045	COG2094	Belongs to the DNA glycosylase MPG family
C7V42_10050	COG0840	transmembrane signaling receptor activity
C7V42_10055	COG0835	chemotaxis
C7V42_10100	COG1262	PFAM Formylglycine-generating sulfatase enzyme
C7V42_10115	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
C7V42_10120	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
C7V42_10120	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
C7V42_10125	COG0802	atpase or kinase
C7V42_10130	COG0860	N-Acetylmuramoyl-L-alanine amidase
C7V42_10135	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
C7V42_10160	COG1028	Short-chain dehydrogenase reductase Sdr
C7V42_10170	COG0501	Belongs to the peptidase M48B family
C7V42_10180	COG2081	HI0933 family
C7V42_10185	COG4681	YaeQ
C7V42_10200	COG0625	glutathione transferase activity
C7V42_10210	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
C7V42_10215	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
C7V42_10220	COG0513	Belongs to the DEAD box helicase family
C7V42_10250	COG0483	inositol monophosphate 1-phosphatase activity
C7V42_10265	COG3300	MHYT domain
C7V42_10265	COG5001	Diguanylate cyclase
C7V42_10275	COG1509	lysine 2,3-aminomutase activity
C7V42_10280	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
C7V42_10295	COG0402	S-adenosylhomocysteine deaminase activity
C7V42_10300	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
C7V42_10335	COG4302	ethanolamine ammonia-lyase activity
C7V42_10350	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
C7V42_10360	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C7V42_10385	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
C7V42_10390	COG0137	argininosuccinate synthase activity
C7V42_10400	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C7V42_10405	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
C7V42_10415	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
C7V42_10475	COG4988	ABC transporter
C7V42_10480	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
C7V42_10490	COG1278	Cold shock
C7V42_10495	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
C7V42_10520	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
C7V42_10540	COG4133	protoheme IX ABC transporter activity
C7V42_10545	COG0436	Aminotransferase
C7V42_10570	COG1187	pseudouridine synthase activity
C7V42_10575	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
C7V42_10580	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
C7V42_10585	COG2350	Protein conserved in bacteria
C7V42_10615	COG1175	transmembrane transport
C7V42_10620	COG0395	ABC-type sugar transport system, permease component
C7V42_10645	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C7V42_10655	COG2957	Belongs to the agmatine deiminase family
C7V42_10670	COG0257	Belongs to the bacterial ribosomal protein bL36 family
C7V42_10675	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
C7V42_10680	COG0539	negative regulation of cytoplasmic translation
C7V42_10695	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
C7V42_10710	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C7V42_10725	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
C7V42_10740	COG0582	viral genome integration into host DNA
C7V42_10780	COG5314	conjugation
C7V42_10825	COG4691	Plasmid stability protein
C7V42_10830	COG1487	ribonuclease activity
C7V42_10865	COG1196	nuclear chromosome segregation
C7V42_10885	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
C7V42_10890	COG0583	DNA-binding transcription factor activity
C7V42_10895	COG0583	DNA-binding transcription factor activity
C7V42_10905	COG1028	Short-chain dehydrogenase reductase Sdr
C7V42_10915	COG0583	DNA-binding transcription factor activity
C7V42_10930	COG2197	response regulator
C7V42_10945	COG1335	isochorismatase
C7V42_10960	COG2814	Major facilitator Superfamily
C7V42_10975	COG1914	H( )-stimulated, divalent metal cation uptake system
C7V42_10980	COG1321	iron dependent repressor
C7V42_10985	COG0590	tRNA wobble adenosine to inosine editing
C7V42_10990	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
C7V42_10995	COG0668	transmembrane transport
C7V42_11005	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
C7V42_11020	COG1028	Short-chain dehydrogenase reductase Sdr
C7V42_11025	COG1183	phosphatidylcholine synthase activity
C7V42_11035	COG3243	poly(R)-hydroxyalkanoic acid synthase
C7V42_11050	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C7V42_11050	COG0723	plastoquinol--plastocyanin reductase activity
C7V42_11060	COG2183	response to ionizing radiation
C7V42_11070	COG2205	protein histidine kinase activity
C7V42_11070	COG0784	Response regulator, receiver
C7V42_11140	COG0800	Aldolase
C7V42_11145	COG0129	dihydroxy-acid dehydratase activity
C7V42_11150	COG0363	glucosamine-6-phosphate deaminase activity
C7V42_11155	COG0837	glucose binding
C7V42_11160	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
C7V42_11190	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
C7V42_11205	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
C7V42_11210	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
C7V42_11220	COG4591	ABC-type transport system involved in lipoprotein release permease component
C7V42_11240	COG0811	peptide transport
C7V42_11250	COG1132	(ABC) transporter
C7V42_11255	COG1663	tetraacyldisaccharide 4'-kinase activity
C7V42_11260	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
C7V42_11265	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C7V42_11275	COG0322	excinuclease ABC activity
C7V42_11305	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
C7V42_11335	COG1530	ribonuclease E activity
C7V42_11345	COG3064	Membrane
C7V42_11350	COG0428	transporter
C7V42_11365	COG2154	pterin-4-alpha-carbinolamine dehydratase
C7V42_11520	COG1858	cytochrome C peroxidase
C7V42_11555	COG0631	protein serine/threonine phosphatase activity
C7V42_11590	COG3501	Rhs element vgr protein
C7V42_11655	COG2801	Transposase and inactivated derivatives
C7V42_11710	COG4566	intracellular signal transduction
C7V42_11720	COG5001	Diguanylate cyclase
C7V42_11730	COG3293	Transposase
C7V42_11740	COG3685	Protein conserved in bacteria
C7V42_11760	COG1648	precorrin-2 dehydrogenase activity
C7V42_11760	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
C7V42_11770	COG0746	molybdenum cofactor guanylyltransferase activity
C7V42_11775	COG0303	'Molybdopterin
C7V42_11780	COG0708	Exodeoxyribonuclease III
C7V42_11820	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C7V42_11825	COG0303	'Molybdopterin
C7V42_11835	COG1160	GTP binding
C7V42_11840	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C7V42_11865	COG0105	UTP biosynthetic process
C7V42_11875	COG1024	Enoyl-CoA hydratase
C7V42_11875	COG1250	3-hydroxyacyl-CoA dehydrogenase
C7V42_11880	COG0183	Belongs to the thiolase family
C7V42_11885	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
C7V42_11890	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
C7V42_11910	COG1674	ftsk spoiiie
C7V42_11915	COG0492	ferredoxin-NADP+ reductase activity
C7V42_11925	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
C7V42_11930	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
C7V42_11935	COG0542	response to heat
C7V42_11940	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
C7V42_11950	COG0482	sulfurtransferase activity
C7V42_11980	COG4585	Histidine kinase
C7V42_11990	COG5002	protein histidine kinase activity
C7V42_12010	COG0835	chemotaxis
C7V42_12010	COG0784	Response regulator, receiver
C7V42_12020	COG1558	bacterial-type flagellum-dependent cell motility
C7V42_12025	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
C7V42_12030	COG1749	Flagellar hook protein flgE
C7V42_12035	COG4787	bacterial-type flagellum-dependent cell motility
C7V42_12045	COG4786	Flagellar basal body rod
C7V42_12050	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
C7V42_12055	COG1706	bacterial-type flagellum-dependent cell motility
C7V42_12075	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C7V42_12080	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
C7V42_12085	COG1516	flagellar protein fliS
C7V42_12110	COG2201	protein-glutamate methylesterase activity
C7V42_12115	COG2204	response regulator
C7V42_12130	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C7V42_12135	COG1028	Short-chain dehydrogenase reductase Sdr
C7V42_12140	COG1028	Short-chain dehydrogenase reductase Sdr
C7V42_12170	COG1677	Flagellar hook-basal body complex protein FliE
C7V42_12220	COG3190	flagellar
C7V42_12230	COG1987	bacterial-type flagellum assembly
C7V42_12235	COG1684	flagellar biosynthetic protein fliR
C7V42_12240	COG3300	MHYT domain
C7V42_12240	COG5001	Diguanylate cyclase
C7V42_12245	COG5001	Diguanylate cyclase
C7V42_12245	COG3300	MHYT domain
C7V42_12275	COG0455	bacterial-type flagellum organization
C7V42_12295	COG0643	Histidine kinase
C7V42_12295	COG2198	Histidine kinase
C7V42_12390	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
C7V42_12395	COG1360	Flagellar Motor Protein
C7V42_12400	COG1192	Involved in chromosome partitioning
C7V42_12405	COG0835	chemotaxis
C7V42_12415	COG0745	RESPONSE REGULATOR receiver
C7V42_12425	COG0840	transmembrane signaling receptor activity
C7V42_12430	COG0840	transmembrane signaling receptor activity
C7V42_12445	COG0840	transmembrane signaling receptor activity
C7V42_12455	COG0840	transmembrane signaling receptor activity
C7V42_12460	COG0840	transmembrane signaling receptor activity
C7V42_12465	COG0840	transmembrane signaling receptor activity
C7V42_12470	COG0840	transmembrane signaling receptor activity
C7V42_12475	COG0840	transmembrane signaling receptor activity
C7V42_12480	COG0840	transmembrane signaling receptor activity
C7V42_12485	COG0840	transmembrane signaling receptor activity
C7V42_12490	COG0840	transmembrane signaling receptor activity
C7V42_12495	COG0840	transmembrane signaling receptor activity
C7V42_12505	COG0835	chemotaxis
C7V42_12515	COG0840	transmembrane signaling receptor activity
C7V42_12530	COG2201	protein-glutamate methylesterase activity
C7V42_12540	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
C7V42_12570	COG0318	PFAM AMP-dependent synthetase and ligase
C7V42_12580	COG3039	Transposase
C7V42_12590	COG1024	Enoyl-CoA hydratase
C7V42_12600	COG2198	Histidine kinase
C7V42_12600	COG0784	Response regulator, receiver
C7V42_12600	COG2205	protein histidine kinase activity
C7V42_12610	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
C7V42_12620	COG3279	Response regulator of the LytR AlgR family
C7V42_12640	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
C7V42_12650	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C7V42_12655	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
C7V42_12665	COG0505	Belongs to the CarA family
C7V42_12670	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
C7V42_12675	COG2258	MOSC domain
C7V42_12680	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C7V42_12725	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
C7V42_12745	COG0277	FAD linked oxidase domain protein
C7V42_12750	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C7V42_12760	COG0531	amino acid
C7V42_12765	COG0531	amino acid
C7V42_12770	COG0235	Class ii aldolase
C7V42_12800	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
C7V42_12800	COG0140	phosphoribosyl-ATP diphosphatase activity
C7V42_12805	COG0107	imidazoleglycerol-phosphate synthase activity
C7V42_12810	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
C7V42_12815	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
C7V42_12825	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
C7V42_12830	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
C7V42_12835	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
C7V42_12845	COG0124	histidyl-tRNA synthetase
C7V42_12850	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C7V42_12860	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
C7V42_12900	COG1012	belongs to the aldehyde dehydrogenase family
C7V42_12920	COG0812	UDP-N-acetylmuramate dehydrogenase activity
C7V42_12925	COG0697	spore germination
C7V42_12935	COG1794	racemase activity, acting on amino acids and derivatives
C7V42_12950	COG0671	phosphoesterase, PA-phosphatase related
C7V42_12955	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
C7V42_12965	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
C7V42_12970	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
C7V42_12995	COG1472	Belongs to the glycosyl hydrolase 3 family
C7V42_13020	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
C7V42_13025	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
C7V42_13030	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
C7V42_13040	COG0617	tRNA 3'-terminal CCA addition
C7V42_13055	COG1469	GTP cyclohydrolase I activity
C7V42_13075	COG0477	Major facilitator Superfamily
C7V42_13085	COG1070	Carbohydrate kinase
C7V42_13095	COG1501	Belongs to the glycosyl hydrolase 31 family
C7V42_13155	COG0800	Aldolase
C7V42_13170	COG3734	2-keto-3-deoxy-galactonokinase
C7V42_13175	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
C7V42_13185	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C7V42_13200	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
C7V42_13205	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
C7V42_13220	COG0351	phosphomethylpyrimidine kinase
C7V42_13220	COG0352	thiamine-phosphate diphosphorylase activity
C7V42_13245	COG0583	DNA-binding transcription factor activity
C7V42_13250	COG1741	Belongs to the pirin family
C7V42_13270	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
C7V42_13280	COG2137	regulation of response to DNA damage stimulus
C7V42_13300	COG1546	Belongs to the CinA family
C7V42_13305	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
C7V42_13310	COG1923	regulation of RNA biosynthetic process
C7V42_13315	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
C7V42_13320	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
C7V42_13325	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C7V42_13330	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
C7V42_13335	COG1534	Rna-binding protein
C7V42_13350	COG1238	metal cluster binding
C7V42_13355	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
C7V42_13360	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
C7V42_13365	COG2840	Smr protein MutS2
C7V42_13390	COG0148	phosphopyruvate hydratase activity
C7V42_13410	COG0504	CTP synthase activity
C7V42_13490	COG3702	type iv secretory pathway
C7V42_13510	COG2948	multi-organism process
C7V42_13530	COG3505	Type IV secretory pathway VirD4
C7V42_13545	COG0556	nucleotide-excision repair
C7V42_13550	COG4969	Belongs to the N-Me-Phe pilin family
C7V42_13590	COG1611	Belongs to the LOG family
C7V42_13600	COG2095	MarC family integral membrane protein
C7V42_13610	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
C7V42_13615	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
C7V42_13650	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
C7V42_13660	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
C7V42_13665	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
C7V42_13670	COG0195	Participates in both transcription termination and antitermination
C7V42_13675	COG0779	Required for maturation of 30S ribosomal subunits
C7V42_13685	COG1007	ATP synthesis coupled electron transport
C7V42_13700	COG0713	ATP synthesis coupled electron transport
C7V42_13710	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C7V42_13715	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
C7V42_13720	COG1034	ATP synthesis coupled electron transport
C7V42_13725	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
C7V42_13730	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
C7V42_13740	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C7V42_13750	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C7V42_13765	COG0149	triose-phosphate isomerase activity
C7V42_13770	COG1028	Short-chain dehydrogenase reductase Sdr
C7V42_13815	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C7V42_13840	COG0133	tryptophan synthase activity
C7V42_13850	COG0135	phosphoribosylanthranilate isomerase activity
C7V42_13855	COG0101	tRNA pseudouridine synthase activity
C7V42_13875	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
C7V42_13880	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C7V42_13890	COG2890	protein-(glutamine-N5) methyltransferase activity
C7V42_13900	COG0688	phosphatidylethanolamine metabolic process
C7V42_13905	COG0688	phosphatidylethanolamine metabolic process
C7V42_13915	COG0433	COG0433 Predicted ATPase
C7V42_13950	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C7V42_13960	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
C7V42_13995	COG0717	Belongs to the dCTP deaminase family
C7V42_14005	COG0489	protein tyrosine kinase activity
C7V42_14025	COG3590	peptidase
C7V42_14030	COG3590	peptidase
C7V42_14050	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C7V42_14055	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C7V42_14060	COG2311	Membrane
C7V42_14065	COG1047	Peptidyl-prolyl cis-trans
C7V42_14070	COG0791	NLP P60 protein
C7V42_14075	COG0791	NLP P60 protein
C7V42_14090	COG1301	dicarboxylic acid transport
C7V42_14095	COG1785	Belongs to the alkaline phosphatase family
C7V42_14100	COG0037	tRNA processing
C7V42_14105	COG1722	exodeoxyribonuclease VII activity
C7V42_14110	COG0142	geranyltranstransferase activity
C7V42_14115	COG4104	PAAR repeat-containing protein
C7V42_14125	COG0312	modulator of DNA gyrase
C7V42_14135	COG0312	modulator of DNA gyrase
C7V42_14145	COG3164	Protein of unknown function
C7V42_14150	COG1530	ribonuclease E activity
C7V42_14160	COG2968	Membrane
C7V42_14175	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
C7V42_14195	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
C7V42_14225	COG3118	belongs to the thioredoxin family
C7V42_14240	COG2155	Conserved Protein
C7V42_14300	COG1132	(ABC) transporter
C7V42_14325	COG1538	Outer membrane efflux protein
C7V42_14330	COG0745	RESPONSE REGULATOR receiver
C7V42_14335	COG5002	protein histidine kinase activity
C7V42_14335	COG5000	phosphorelay sensor kinase activity
C7V42_14340	COG0475	glutathione-regulated potassium exporter activity
C7V42_14345	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C7V42_14350	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
C7V42_14380	COG1187	pseudouridine synthase activity
C7V42_14385	COG5002	protein histidine kinase activity
C7V42_14385	COG5001	Diguanylate cyclase
C7V42_14435	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
C7V42_14500	COG0667	Aldo Keto reductase
C7V42_14505	COG2814	Major facilitator Superfamily
C7V42_14510	COG0583	DNA-binding transcription factor activity
C7V42_14525	COG2207	Transcriptional regulator
C7V42_14560	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C7V42_14585	COG1538	Outer membrane efflux protein
C7V42_14605	COG0735	belongs to the Fur family
C7V42_14610	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
C7V42_14635	COG4452	Inner membrane protein CreD
C7V42_14645	COG2205	protein histidine kinase activity
C7V42_14660	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
C7V42_14670	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
C7V42_14680	COG2198	Histidine kinase
C7V42_14680	COG0643	Histidine kinase
C7V42_14685	COG0840	transmembrane signaling receptor activity
C7V42_14690	COG0835	chemotaxis
C7V42_14700	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
C7V42_14710	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C7V42_14715	COG3590	peptidase
C7V42_14725	COG0588	phosphoglycerate mutase activity
C7V42_14730	COG1515	deoxyribonuclease V activity
C7V42_14735	COG1741	Belongs to the pirin family
C7V42_14755	COG1741	Belongs to the pirin family
C7V42_14760	COG1966	Carbon starvation protein
C7V42_14765	COG2879	small protein
C7V42_14795	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
C7V42_14800	COG1529	Aldehyde oxidase and xanthine dehydrogenase
C7V42_14810	COG2080	2 iron, 2 sulfur cluster binding
C7V42_14815	COG0604	alcohol dehydrogenase
C7V42_14815	COG3321	synthase
C7V42_14815	COG1028	Short-chain dehydrogenase reductase Sdr
C7V42_14820	COG2203	Gaf domain
C7V42_14820	COG4251	negative regulation of phosphorylation
C7V42_14820	COG5001	Diguanylate cyclase
C7V42_14820	COG3706	GGDEF domain
C7V42_14825	COG0629	single-stranded DNA binding
C7V42_14830	COG0142	geranyltranstransferase activity
C7V42_14855	COG0527	aspartate kinase activity
C7V42_14860	COG0384	phenazine biosynthesis protein PhzF
C7V42_14865	COG0384	phenazine biosynthesis protein PhzF
C7V42_14875	COG1764	response to oxidative stress
C7V42_14885	COG0540	Belongs to the ATCase OTCase family
C7V42_14890	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
C7V42_14895	COG1678	Uncharacterized ACR, COG1678
C7V42_14905	COG0519	Catalyzes the synthesis of GMP from XMP
C7V42_14930	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
C7V42_14945	COG4942	peptidase
C7V42_14965	COG0693	protein deglycase activity
C7V42_14975	COG1959	2 iron, 2 sulfur cluster binding
C7V42_14980	COG0719	Fe-S assembly protein
C7V42_14985	COG0396	ATPase activity
C7V42_14990	COG0719	Fe-S assembly protein
C7V42_14995	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
C7V42_15015	COG4774	siderophore transport
C7V42_15020	COG3128	pkhd-type hydroxylase
C7V42_15045	COG1477	protein flavinylation
C7V42_15050	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
C7V42_15060	COG1555	photosystem II stabilization
C7V42_15065	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C7V42_15075	COG3178	'Phosphotransferase
C7V42_15080	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
C7V42_15095	COG0628	permease
C7V42_15105	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
C7V42_15115	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
C7V42_15130	COG3039	Transposase
C7V42_15145	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
C7V42_15150	COG0271	Belongs to the BolA IbaG family
C7V42_15160	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
C7V42_15170	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
C7V42_15175	COG1137	ATPase activity
C7V42_15190	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7V42_15200	COG1660	Displays ATPase and GTPase activities
C7V42_15210	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7V42_15215	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C7V42_15225	COG2239	Acts as a magnesium transporter
C7V42_15240	COG1294	oxidase, subunit
C7V42_15245	COG1271	oxidase subunit
C7V42_15255	COG1113	amino acid transport
C7V42_15260	COG3866	Pectate lyase
C7V42_15275	COG2197	response regulator
C7V42_15280	COG0531	amino acid
C7V42_15350	COG0789	Transcriptional regulator
C7V42_15355	COG2814	Major facilitator Superfamily
C7V42_15365	COG0754	glutathionylspermidine amidase activity
C7V42_15390	COG1842	Phage shock protein A
C7V42_15400	COG0259	pyridoxamine-phosphate oxidase activity
C7V42_15405	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
C7V42_15410	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
C7V42_15425	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
C7V42_15445	COG0784	Response regulator, receiver
C7V42_15445	COG5002	protein histidine kinase activity
C7V42_15450	COG0784	Response regulator, receiver
C7V42_15450	COG2198	Histidine kinase
C7V42_15450	COG2205	protein histidine kinase activity
C7V42_15455	COG2353	YceI-like domain
C7V42_15480	COG1760	l-serine dehydratase
C7V42_15490	COG0527	aspartate kinase activity
C7V42_15490	COG0460	homoserine dehydrogenase
C7V42_15495	COG0626	cystathionine gamma-synthase activity
C7V42_15500	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
C7V42_15505	COG0739	heme binding
C7V42_15510	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
C7V42_15515	COG1272	protein, Hemolysin III
C7V42_15520	COG2982	Protein involved in outer membrane biogenesis
C7V42_15530	COG0463	Glycosyl transferase, family 2
C7V42_15540	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
C7V42_15555	COG1309	transcriptional regulator
C7V42_15560	COG2267	carboxylic ester hydrolase activity
C7V42_15565	COG1960	acyl-CoA dehydrogenase activity
C7V42_15600	COG0509	glycine decarboxylation via glycine cleavage system
C7V42_15605	COG0404	The glycine cleavage system catalyzes the degradation of glycine
C7V42_15615	COG1742	UPF0060 membrane protein
C7V42_15620	COG3956	TIGRFAM MazG family protein
C7V42_15630	COG0494	nUDIX hydrolase
C7V42_15640	COG1385	rRNA (uridine-N3-)-methyltransferase activity
C7V42_15645	COG0837	glucose binding
C7V42_15660	COG1388	LysM domain
C7V42_15660	COG3858	chitin binding
C7V42_15695	COG1472	Belongs to the glycosyl hydrolase 3 family
C7V42_15760	COG3537	Alpha-1,2-mannosidase
C7V42_15800	COG3142	Participates in the control of copper homeostasis
C7V42_15805	COG1446	asparaginase
C7V42_15835	COG2201	protein-glutamate methylesterase activity
C7V42_15845	COG0840	transmembrane signaling receptor activity
C7V42_15850	COG0835	chemotaxis
C7V42_15865	COG0189	ligase activity
C7V42_15875	COG1397	ADP-ribosylglycohydrolase
C7V42_15885	COG1199	ATP-dependent helicase activity
C7V42_15895	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C7V42_15905	COG1215	transferase activity, transferring glycosyl groups
C7V42_15920	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C7V42_15930	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
C7V42_15935	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
C7V42_15965	COG0837	glucose binding
C7V42_15980	COG1643	Atp-dependent helicase
C7V42_15985	COG0783	Belongs to the Dps family
C7V42_15990	COG0514	ATP-dependent DNA helicase (RecQ)
C7V42_16025	COG1187	pseudouridine synthase activity
C7V42_16045	COG0840	transmembrane signaling receptor activity
C7V42_16075	COG0602	queuosine metabolic process
C7V42_16085	COG2885	chlorophyll binding
C7V42_16090	COG0823	Involved in the tonB-independent uptake of proteins
C7V42_16100	COG0848	biopolymer transport protein
C7V42_16110	COG0824	Thioesterase
C7V42_16120	COG3158	transport of potassium into the cell
C7V42_16130	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
C7V42_16150	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
C7V42_16170	COG0477	Major facilitator Superfamily
C7V42_16200	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
C7V42_16210	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
C7V42_16215	COG0174	glutamine synthetase
C7V42_16270	COG0488	(ABC) transporter
C7V42_16310	COG4651	solute:proton antiporter activity
C7V42_16310	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
C7V42_16320	COG4772	TonB-dependent receptor
C7V42_16330	COG4264	IucA IucC family
C7V42_16335	COG2814	Major facilitator Superfamily
C7V42_16345	COG0019	diaminopimelate decarboxylase activity
C7V42_16400	COG0542	response to heat
C7V42_16405	COG1116	anion transmembrane transporter activity
C7V42_16410	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C7V42_16415	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C7V42_16420	COG0667	Aldo Keto reductase
C7V42_16430	COG4771	TonB-dependent receptor
C7V42_16435	COG2827	Endonuclease containing a URI domain
C7V42_16485	COG1877	trehalose-phosphatase activity
C7V42_16490	COG3387	PFAM Glycoside hydrolase 15-related
C7V42_16505	COG0840	transmembrane signaling receptor activity
C7V42_16510	COG3011	Protein conserved in bacteria
C7V42_16525	COG0564	pseudouridine synthase activity
C7V42_16530	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C7V42_16535	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C7V42_16535	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
C7V42_16550	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
C7V42_16555	COG0045	succinate-CoA ligase (ADP-forming) activity
C7V42_16585	COG2194	sulfuric ester hydrolase activity
C7V42_16590	COG4969	Belongs to the N-Me-Phe pilin family
C7V42_16600	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
C7V42_16615	COG0745	RESPONSE REGULATOR receiver
C7V42_16830	COG5001	Diguanylate cyclase
C7V42_16940	COG3077	Addiction module antitoxin, RelB DinJ family
C7V42_16970	COG0583	DNA-binding transcription factor activity
C7V42_16975	COG1396	sequence-specific DNA binding
C7V42_16995	COG0582	viral genome integration into host DNA
C7V42_17015	COG2022	thiamine diphosphate biosynthetic process
C7V42_17020	COG0220	tRNA (guanine-N7-)-methyltransferase activity
C7V42_17025	COG3273	potassium ion transport
C7V42_17025	COG0471	metal ion transport
C7V42_17045	COG1970	mechanosensitive ion channel activity
C7V42_17055	COG1609	Transcriptional regulator
C7V42_17085	COG4948	Mandelate Racemase Muconate Lactonizing
C7V42_17100	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C7V42_17120	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C7V42_17130	COG2895	sulfate adenylyltransferase (ATP) activity
C7V42_17130	COG0529	Catalyzes the synthesis of activated sulfate
C7V42_17140	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
C7V42_17145	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C7V42_17170	COG0784	Response regulator, receiver
C7V42_17170	COG2198	Histidine kinase
C7V42_17170	COG2205	protein histidine kinase activity
C7V42_17190	COG0583	DNA-binding transcription factor activity
C7V42_17215	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
C7V42_17220	COG3588	fructose-bisphosphate aldolase
C7V42_17230	COG0469	pyruvate kinase activity
C7V42_17265	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C7V42_17285	COG3047	cAMP biosynthetic process
C7V42_17295	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7V42_17295	COG3453	Protein conserved in bacteria
C7V42_17300	COG0725	ABC transporter, periplasmic molybdate-binding protein
C7V42_17305	COG4149	molybdate abc transporter
C7V42_17345	COG1376	ErfK ybiS ycfS ynhG family protein
C7V42_17350	COG0739	heme binding
C7V42_17355	COG1028	Short-chain dehydrogenase reductase Sdr
C7V42_17360	COG0583	DNA-binding transcription factor activity
C7V42_17365	COG4773	Receptor
C7V42_17375	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
C7V42_17380	COG1301	dicarboxylic acid transport
C7V42_17395	COG2304	oxidoreductase activity
C7V42_17415	COG0714	Associated with various cellular activities
C7V42_17445	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
C7V42_17460	COG0254	rRNA binding
C7V42_17465	COG1957	nucleoside hydrolase
C7V42_17470	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
C7V42_17480	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C7V42_17485	COG1758	RNA polymerase activity
C7V42_17495	COG1561	YicC-like family, N-terminal region
C7V42_17500	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
C7V42_17515	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C7V42_17530	COG0006	proline dipeptidase activity
C7V42_17540	COG0006	proline dipeptidase activity
C7V42_17565	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
C7V42_17585	COG2912	Transglutaminase-like superfamily
C7V42_17590	COG1773	rubredoxin
C7V42_17595	COG0352	thiamine-phosphate diphosphorylase activity
C7V42_17620	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
C7V42_17630	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
C7V42_17635	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
C7V42_17665	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C7V42_17670	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C7V42_17680	COG1028	Short-chain dehydrogenase reductase Sdr
C7V42_17690	COG0671	phosphoesterase, PA-phosphatase related
C7V42_17695	COG3781	membrane
C7V42_17705	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
C7V42_17725	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
C7V42_17735	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
C7V42_17755	COG3710	Transcriptional regulator
C7V42_17775	COG0840	transmembrane signaling receptor activity
C7V42_17805	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
C7V42_17810	COG0473	3-isopropylmalate dehydrogenase activity
C7V42_17815	COG2226	methyltransferase
C7V42_17820	COG0066	3-isopropylmalate dehydratase activity
C7V42_17825	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
C7V42_17840	COG3706	GGDEF domain
C7V42_17855	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
C7V42_17860	COG1538	Outer membrane efflux protein
C7V42_17865	COG1519	Transferase
C7V42_17870	COG1560	Kdo2-lipid A biosynthetic process
C7V42_17935	COG0280	phosphate acetyltransferase
C7V42_17935	COG0281	malic enzyme
C7V42_17940	COG1301	dicarboxylic acid transport
C7V42_17955	COG4191	Histidine kinase
C7V42_17970	COG0583	DNA-binding transcription factor activity
C7V42_17975	COG0667	Aldo Keto reductase
C7V42_17990	COG2197	response regulator
C7V42_18000	COG0642	Histidine kinase
C7V42_18025	COG2851	Citrate transporter
C7V42_18030	COG1028	Short-chain dehydrogenase reductase Sdr
C7V42_18035	COG1609	Transcriptional regulator
C7V42_18045	COG2211	Major facilitator Superfamily
C7V42_18070	COG1162	GTPase activity
C7V42_18075	COG0436	Aminotransferase
C7V42_18090	COG0726	polysaccharide deacetylase
C7V42_18095	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
C7V42_18110	COG3964	amidohydrolase
C7V42_18115	COG0402	S-adenosylhomocysteine deaminase activity
C7V42_18175	COG3791	Glutathione-dependent formaldehyde-activating
C7V42_18195	COG0745	RESPONSE REGULATOR receiver
C7V42_18200	COG2205	protein histidine kinase activity
C7V42_18225	COG0218	Necessary for normal cell division and for the maintenance of normal septation
C7V42_18240	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C7V42_18260	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
C7V42_18265	COG0456	acetyltransferase
C7V42_18275	COG1183	phosphatidylcholine synthase activity
C7V42_18285	COG0442	prolyl-tRNA aminoacylation
C7V42_18300	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
C7V42_18305	COG1127	ABC transporter
C7V42_18310	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
C7V42_18310	COG3218	ABC-type transport auxiliary lipoprotein component
C7V42_18325	COG3293	Transposase
C7V42_18355	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C7V42_18360	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
C7V42_18360	COG0662	Cupin 2, conserved barrel domain protein
C7V42_18385	COG2086	electron transfer activity
C7V42_18400	COG0546	phosphoglycolate phosphatase activity
C7V42_18400	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
C7V42_18405	COG0277	FAD linked oxidase domain protein
C7V42_18415	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C7V42_18445	COG0438	transferase activity, transferring glycosyl groups
C7V42_18480	COG0626	cystathionine gamma-synthase activity
C7V42_18510	COG0625	glutathione transferase activity
C7V42_18525	COG0513	Belongs to the DEAD box helicase family
C7V42_18535	COG0720	synthase
C7V42_18545	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
C7V42_18550	COG1956	GAF domain-containing protein
C7V42_18560	COG0546	phosphoglycolate phosphatase activity
C7V42_18565	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C7V42_18590	COG0339	signal peptide processing
C7V42_18640	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
C7V42_18645	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C7V42_18650	COG1136	(ABC) transporter
C7V42_18655	COG0577	efflux transmembrane transporter activity
C7V42_18660	COG0577	efflux transmembrane transporter activity
C7V42_18670	COG4191	Histidine kinase
C7V42_18675	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
C7V42_18705	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
C7V42_18710	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
C7V42_18715	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
C7V42_18730	COG0356	it plays a direct role in the translocation of protons across the membrane
C7V42_18750	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C7V42_18760	COG0508	dehydrogenase complex catalyzes the overall conversion of
C7V42_18805	COG2011	ABC-type metal ion transport system permease component
C7V42_18810	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
C7V42_18815	COG0697	spore germination
C7V42_18820	COG1666	GTP binding
C7V42_18830	COG5002	protein histidine kinase activity
C7V42_18830	COG2198	Histidine kinase
C7V42_18830	COG0784	Response regulator, receiver
C7V42_18850	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C7V42_18855	COG1187	pseudouridine synthase activity
C7V42_18860	COG2813	Specifically methylates the guanine in position
C7V42_18890	COG2202	Pas domain
C7V42_18890	COG2205	protein histidine kinase activity
C7V42_18910	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C7V42_18915	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C7V42_18920	COG1522	sequence-specific DNA binding
C7V42_18960	COG0745	RESPONSE REGULATOR receiver
C7V42_18975	COG1404	Belongs to the peptidase S8 family
C7V42_19000	COG0842	Transport permease protein
C7V42_19005	COG1131	(ABC) transporter
C7V42_19010	COG0025	NhaP-type Na H and K H
C7V42_19020	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
C7V42_19025	COG1573	uracil-dna glycosylase
C7V42_19040	COG3384	dioxygenase
C7V42_19050	COG0583	DNA-binding transcription factor activity
C7V42_19060	COG0667	Aldo Keto reductase
C7V42_19070	COG3590	peptidase
C7V42_19085	COG0531	amino acid
C7V42_19100	COG2972	Histidine kinase
C7V42_19125	COG3685	Protein conserved in bacteria
C7V42_19130	COG3546	catalase activity
C7V42_19180	COG1271	oxidase subunit
C7V42_19185	COG1294	oxidase, subunit
C7V42_19200	COG1028	Short-chain dehydrogenase reductase Sdr
C7V42_19205	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C7V42_19225	COG1132	(ABC) transporter
C7V42_19240	COG1063	alcohol dehydrogenase
C7V42_19330	COG0038	chloride channel
C7V42_19340	COG0024	Methionine aminopeptidase
C7V42_19360	COG3039	Transposase
C7V42_19405	COG3039	Transposase
C7V42_19455	COG0582	viral genome integration into host DNA
C7V42_19470	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C7V42_19475	COG1490	D-aminoacyl-tRNA deacylase activity
C7V42_19480	COG1560	Kdo2-lipid A biosynthetic process
C7V42_19525	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C7V42_19525	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
C7V42_19530	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
C7V42_19535	COG0242	peptide deformylase activity
C7V42_19540	COG1652	LysM domain
C7V42_19545	COG0758	DNA mediated transformation
C7V42_19565	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C7V42_19565	COG1754	DNA topoisomerase type I activity
C7V42_19585	COG1028	Short-chain dehydrogenase reductase Sdr
C7V42_19595	COG0616	signal peptide processing
C7V42_19600	COG0534	Mate efflux family protein
C7V42_19620	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
C7V42_19625	COG0625	glutathione transferase activity
C7V42_19640	COG1252	NADH dehydrogenase
C7V42_19645	COG2860	membrane
C7V42_19650	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C7V42_19660	COG3437	response regulator, receiver
C7V42_19665	COG2177	Part of the ABC transporter FtsEX involved in
C7V42_19670	COG2884	Cell division ATP-binding protein ftsE
C7V42_19680	COG3118	belongs to the thioredoxin family
C7V42_19685	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
C7V42_19745	COG1518	maintenance of DNA repeat elements
C7V42_19750	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
C7V42_19770	COG1652	LysM domain
C7V42_19775	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
C7V42_19775	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
C7V42_19790	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C7V42_19810	COG5383	Protein conserved in bacteria
C7V42_19855	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
C7V42_19860	COG3023	N-Acetylmuramoyl-L-alanine amidase
C7V42_19870	COG4948	Mandelate Racemase Muconate Lactonizing
C7V42_19880	COG0531	amino acid
C7V42_19895	COG4682	membrane
C7V42_19900	COG2133	pyrroloquinoline quinone binding
C7V42_19910	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
C7V42_19920	COG0828	Belongs to the bacterial ribosomal protein bS21 family
C7V42_19925	COG1610	YqeY-like protein
C7V42_19930	COG1295	ribonuclease BN
C7V42_19935	COG0358	DNA primase activity
C7V42_19950	COG0109	protoheme IX farnesyltransferase activity
C7V42_19980	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
C7V42_19995	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
C7V42_20045	COG0739	heme binding
C7V42_20060	COG2211	Major facilitator Superfamily
C7V42_20065	COG0708	Exodeoxyribonuclease III
C7V42_20080	COG1192	Involved in chromosome partitioning
C7V42_20085	COG1475	DNA binding
C7V42_20105	COG0463	Glycosyl transferase, family 2
C7V42_20130	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
C7V42_20140	COG0018	arginyl-trna synthetase
C7V42_20155	COG4221	oxidoreductase activity
C7V42_20175	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7V42_20175	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7V42_20180	COG1166	arginine decarboxylase activity
C7V42_20185	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
C7V42_20215	COG3291	Pkd domain containing protein
C7V42_20215	COG3525	Glycosyl hydrolase, family 20, catalytic domain
C7V42_20230	COG0606	chelatase, subunit chli
C7V42_20245	COG4943	cyclic-guanylate-specific phosphodiesterase activity
C7V42_20270	COG1690	Belongs to the RtcB family
C7V42_20305	COG1090	epimerase
C7V42_20315	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C7V42_20335	COG0628	permease
C7V42_20340	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C7V42_20345	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
C7V42_20360	COG0753	catalase activity
C7V42_20375	COG2197	response regulator
C7V42_20380	COG4585	Histidine kinase
C7V42_20385	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C7V42_20390	COG1136	(ABC) transporter
C7V42_20415	COG0697	spore germination
C7V42_20440	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7V42_20445	COG0180	Tryptophanyl-tRNA synthetase
C7V42_20450	COG3237	CsbD-like
C7V42_20495	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
C7V42_20515	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
C7V42_20515	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
C7V42_20525	COG3228	Belongs to the MtfA family
C7V42_20540	COG2205	protein histidine kinase activity
C7V42_20545	COG0745	RESPONSE REGULATOR receiver
C7V42_20555	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C7V42_20590	COG1199	ATP-dependent helicase activity
C7V42_20605	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
C7V42_20620	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
C7V42_20680	COG0625	glutathione transferase activity
C7V42_20715	COG4555	ABC transporter
C7V42_20730	COG1476	TRANSCRIPTIONal
C7V42_20745	COG1230	cation diffusion facilitator family transporter
C7V42_20750	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
C7V42_20755	COG1131	(ABC) transporter
C7V42_20760	COG0842	Transport permease protein
C7V42_20770	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
C7V42_20795	COG1607	acyl-coa hydrolase
C7V42_20800	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7V42_20820	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C7V42_20825	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C7V42_20840	COG1042	CoA-binding domain protein
C7V42_20840	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C7V42_20840	COG0045	succinate-CoA ligase (ADP-forming) activity
C7V42_20850	COG2239	Acts as a magnesium transporter
C7V42_20865	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
C7V42_20870	COG3387	PFAM Glycoside hydrolase 15-related
C7V42_20885	COG3100	YcgL domain-containing protein
C7V42_20890	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C7V42_20900	COG0463	Glycosyl transferase, family 2
C7V42_20915	COG1028	Short-chain dehydrogenase reductase Sdr
C7V42_20940	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
C7V42_20955	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C7V42_21015	COG1121	(ABC) transporter
C7V42_21030	COG3220	belongs to the UPF0276 family
C7V42_21155	COG3293	Transposase
C7V42_21165	COG0210	DNA helicase
C7V42_21185	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C7V42_21195	COG2159	amidohydrolase
C7V42_21200	COG0267	Belongs to the bacterial ribosomal protein bL33 family
C7V42_21205	COG0227	Belongs to the bacterial ribosomal protein bL28 family
C7V42_21215	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C7V42_21240	COG0357	Ribosomal RNA small subunit methyltransferase G
C7V42_21255	COG2091	lysine biosynthetic process via aminoadipic acid
C7V42_21270	COG0708	Exodeoxyribonuclease III
C7V42_21275	COG1940	carbohydrate kinase activity
C7V42_21285	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C7V42_21295	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C7V42_21300	COG3162	membrane
C7V42_21360	COG1028	Short-chain dehydrogenase reductase Sdr
C7V42_21365	COG0179	Fumarylacetoacetate (FAA) hydrolase
C7V42_21370	COG4948	Mandelate Racemase Muconate Lactonizing
C7V42_21375	COG3254	rhamnose metabolic process
C7V42_21380	COG0738	Major facilitator superfamily
C7V42_21385	COG1414	Transcriptional regulator
C7V42_21400	COG2205	protein histidine kinase activity
C7V42_21410	COG3459	Glycosyltransferase 36 associated
C7V42_21415	COG2211	Major facilitator Superfamily
C7V42_21420	COG3265	gluconokinase activity
C7V42_21450	COG2911	Protein conserved in bacteria
C7V42_21455	COG0729	surface antigen
C7V42_21480	COG4771	TonB-dependent receptor
C7V42_21485	COG0457	Tetratricopeptide repeat
C7V42_21495	COG0752	glycyl-tRNA synthetase alpha subunit
C7V42_21500	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C7V42_21515	COG0518	GMP synthase (glutamine-hydrolyzing) activity
C7V42_21515	COG0519	Catalyzes the synthesis of GMP from XMP
C7V42_21525	COG0805	protein transport
C7V42_21530	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C7V42_21535	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C7V42_21545	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
C7V42_21565	COG2974	May be involved in recombination
C7V42_21570	COG0037	tRNA processing
C7V42_21590	COG3661	Belongs to the glycosyl hydrolase 67 family
C7V42_21600	COG4948	Mandelate Racemase Muconate Lactonizing
C7V42_21610	COG1472	Belongs to the glycosyl hydrolase 3 family
C7V42_21615	COG0246	Mannitol dehydrogenase
C7V42_21680	COG3386	PFAM SMP-30 Gluconolaconase
C7V42_21705	COG1904	glucuronate isomerase
C7V42_21710	COG3693	PFAM glycoside hydrolase, family 10
C7V42_21730	COG2211	Major facilitator Superfamily
C7V42_21770	COG2937	Belongs to the GPAT DAPAT family
C7V42_21800	COG0284	orotidine-5'-phosphate decarboxylase activity
C7V42_21805	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
C7V42_21810	COG3132	Protein of unknown function, DUF480
C7V42_21825	COG0210	DNA helicase
C7V42_21830	COG1435	thymidine kinase activity
C7V42_21840	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
C7V42_21850	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
C7V42_21905	COG0676	glucose-6-phosphate 1-epimerase activity
C7V42_21915	COG3012	SEC-C Motif Domain Protein
C7V42_21920	COG0730	response to heat
C7V42_21940	COG0302	gtp cyclohydrolase
C7V42_21955	COG1566	PFAM secretion protein HlyD family protein
C7V42_21965	COG1289	transmembrane transporter activity
C7V42_21970	COG0477	Major facilitator Superfamily
C7V42_21980	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C7V42_22025	COG0564	pseudouridine synthase activity
C7V42_22095	COG3549	Plasmid maintenance system killer
C7V42_22100	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C7V42_22105	COG1074	ATP-dependent DNA helicase activity
C7V42_22110	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
C7V42_22145	COG1127	ABC transporter
C7V42_22150	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
C7V42_22155	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
C7V42_22170	COG2853	Lipoprotein
C7V42_22180	COG0386	Belongs to the glutathione peroxidase family
C7V42_22190	COG1322	Protein conserved in bacteria
C7V42_22195	COG0604	alcohol dehydrogenase
C7V42_22200	COG0583	DNA-binding transcription factor activity
C7V42_22225	COG0531	amino acid
C7V42_22250	COG0745	RESPONSE REGULATOR receiver
C7V42_22250	COG3706	GGDEF domain
C7V42_22255	COG3835	regulator
C7V42_22260	COG1929	Belongs to the glycerate kinase type-1 family
C7V42_22265	COG2271	Major facilitator Superfamily
C7V42_22285	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
C7V42_22295	COG0861	Integral membrane protein TerC family
C7V42_22305	COG0584	glycerophosphoryl diester phosphodiesterase
C7V42_22320	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
C7V42_22330	COG0706	membrane insertase activity
C7V42_22340	COG0230	Belongs to the bacterial ribosomal protein bL34 family