locus-tag	class	description
BI313_00120	ENOG4107SKI	cobyrinic Acid a,c-diamide synthase
BI313_00280	ENOG4105DVT	helicase
BI313_00290	ENOG4108R7K	Metal Dependent Phosphohydrolase
BI313_00300	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
BI313_00320	ENOG4105T95	Thiol disulfide interChange protein
BI313_00345	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
BI313_00360	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
BI313_00375	ENOG4105DH7	May be involved in recombination (By similarity)
BI313_00475	ENOG4108UUM	single-stranded DNA-binding protein
BI313_00500	ENOG4105CB5	ATP-dependent DNA helicase recG
BI313_00530	ENOG4105C4R	Atp-dependent dna helicase
BI313_00600	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
BI313_00695	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
BI313_00720	ENOG4105EP1	Efflux transporter rnd family, mfp subunit
BI313_00725	ENOG4108IJF	Heavy metal efflux pump, CzcA
BI313_00740	ENOG41088SP	formiminoglutamate hydrolase
BI313_00795	ENOG4105E3B	Multicopper oxidase
BI313_00820	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
BI313_00835	ENOG4107WAU	Protein tyrosine phosphatase
BI313_00840	ENOG4105K89	arsenate reductase
BI313_00845	ENOG4105CAU	Arsenical resistance protein, ArsH
BI313_01035	ENOG4108NSC	Pfam:DUF88
BI313_01090	ENOG4105C9U	ATP-dependent DNA helicase RecQ
BI313_01285	ENOG4105BZU	Histidine kinase
BI313_01320	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
BI313_01325	ENOG41090R7	Ferric uptake
BI313_01330	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
BI313_01335	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
BI313_01340	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BI313_01345	ENOG4105CFG	Acts as a chaperone (By similarity)
BI313_01385	ENOG4105C5Q	Transcriptional regulator
BI313_01390	ENOG4105BZ1	(ABC) transporter
BI313_01400	ENOG4108URH	decarboxylase
BI313_01410	ENOG4105C7S	Dehydrogenase
BI313_01415	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
BI313_01425	ENOG4105EZE	Cupin 4 family protein
BI313_01435	ENOG4107QTF	adenylosuccinate lyase
BI313_01440	ENOG4105C37	(CBS) domain
BI313_01470	ENOG4105CZV	ABC transporter
BI313_01475	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
BI313_01490	ENOG4108V1T	peptidylprolyl cis-trans isomerase
BI313_01505	ENOG4105EXC	Acyl-transferase
BI313_01520	ENOG4105ETE	Transcriptional regulator (LacI family
BI313_01530	ENOG4105D7K	pfkb domain protein
BI313_01540	ENOG4105C3R	Methionine synthase
BI313_01545	ENOG4105C3R	Methionine synthase
BI313_01555	ENOG4105C1G	acyl-Coa dehydrogenase
BI313_01570	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
BI313_01580	ENOG4105C2N	RNA methyltransferase TrmH family group 3
BI313_01585	ENOG4105BZU	Histidine kinase
BI313_01590	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
BI313_01600	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
BI313_01605	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
BI313_01610	ENOG4105E2Z	phosphate ABC transporter (Permease
BI313_01615	ENOG4105C8U	phosphate abc transporter
BI313_01620	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
BI313_01640	ENOG4107B2H	carbonic anhydrase
BI313_01645	ENOG4105CHH	sulfate transporter
BI313_01650	ENOG4105CSM	endonuclease III
BI313_01660	ENOG4105E39	Enoyl-CoA hydratase
BI313_01665	ENOG4108V1T	peptidylprolyl cis-trans isomerase
BI313_01670	ENOG4105P8F	nudix hydrolase
BI313_01675	ENOG4105KHC	sulfurtransferase
BI313_01705	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
BI313_01715	ENOG4105C5H	ABC transporter
BI313_01720	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
BI313_01730	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
BI313_01755	ENOG4105CJB	Exodeoxyribonuclease I
BI313_01760	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
BI313_01765	ENOG4105CKY	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively (By similarity)
BI313_01775	ENOG4105C3W	Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate (By similarity)
BI313_01780	ENOG41077A9	carbonic anhydrase
BI313_01805	ENOG4105C5S	asparaginyl-tRNA synthetase
BI313_01810	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
BI313_01820	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
BI313_01825	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
BI313_01835	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
BI313_01845	ENOG4105CIH	Imidazole acetol-phosphate transaminase
BI313_01850	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
BI313_01880	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
BI313_01885	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
BI313_01890	ENOG4105DZG	Dehydrogenase
BI313_01905	ENOG4105CGP	Urocanate hydratase
BI313_01915	ENOG4105C84	Histidine ammonia-lyase
BI313_01920	ENOG4105CI2	imidazolone-5-propionate hydrolase
BI313_01955	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
BI313_01960	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
BI313_01965	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
BI313_01975	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
BI313_01990	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
BI313_01995	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
BI313_02000	ENOG4105CC0	LysR family Transcriptional regulator
BI313_02040	ENOG4108JJB	ABC transporter
BI313_02070	ENOG4105W5Q	DNA repair protein (RadC
BI313_02105	ENOG4107QMH	DNA methylase
BI313_02240	ENOG4105C8Q	Methyl-accepting chemotaxis
BI313_02260	ENOG4105CQZ	Histidine kinase
BI313_02270	ENOG4105KWW	Biogenesis protein
BI313_02275	ENOG4107QX9	Thiol disulfide interChange protein
BI313_02280	ENOG4105DA4	cytochrome c-type biogenesis protein
BI313_02285	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
BI313_02295	ENOG41060IM	Heme exporter protein
BI313_02310	ENOG4105EMN	RNA polymerase sigma factor
BI313_02345	ENOG4105EGZ	biosynthesis protein
BI313_02380	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
BI313_02390	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
BI313_02415	ENOG41079KZ	Major Facilitator Superfamily
BI313_02420	ENOG4105DEN	Luciferase family
BI313_02455	ENOG4107S90	membrAne
BI313_02465	ENOG4105EAF	CDP-diacylglycerol pyrophosphatase (EC 3.6.1.26)
BI313_02470	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
BI313_02480	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
BI313_02485	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
BI313_02495	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
BI313_02500	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
BI313_02510	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
BI313_02515	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
BI313_02520	ENOG4108DG9	Smr protein MutS2
BI313_02525	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
BI313_02530	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
BI313_02535	ENOG4108UM1	dedA family
BI313_02540	ENOG4108K5P	(LipO)protein
BI313_02545	ENOG4108UIV	Protein of unknown function (DUF498/DUF598)
BI313_02550	ENOG4105HBR	Rna-binding protein
BI313_02555	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
BI313_02560	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
BI313_02565	ENOG4105EEI	dihydropteroate synthase
BI313_02570	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
BI313_02575	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
BI313_02580	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
BI313_02585	ENOG4107TH8	cina domain protein
BI313_02595	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
BI313_02600	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
BI313_02610	ENOG4105Y3E	Modulates RecA activity (By similarity)
BI313_02615	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
BI313_02620	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
BI313_02630	ENOG4107SDU	Methyl-accepting chemotaxis
BI313_02640	ENOG4105CWB	LysR family transcriptional Regulator
BI313_02665	ENOG4105DWF	phosphomethylpyrimidine kinase
BI313_02680	ENOG4108IAB	Phoh family
BI313_02685	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BI313_02700	ENOG4107TUS	Dihydrodipicolinate synthase
BI313_02710	ENOG4108Z4U	Ferredoxin
BI313_02715	ENOG4105EI3	2-dehydro-3-deoxygalactonokinase EC 2.7.1.58
BI313_02730	ENOG4108RTU	Aldolase
BI313_02765	ENOG4105C4C	beta-galactosidase
BI313_02780	ENOG4105CMG	Carbohydrate kinase
BI313_02785	ENOG4105C93	Xylose Isomerase
BI313_02810	ENOG4108KNB	n-acetylmuramoyl-l-alanine amidase
BI313_02825	ENOG4105DJ0	Poly(A) Polymerase
BI313_02830	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BI313_02835	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
BI313_02840	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
BI313_02845	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
BI313_02905	ENOG4108UYB	regulatoR
BI313_02915	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
BI313_02920	ENOG410841Q	phosphoesterase PA-phosphatase related protein
BI313_02935	ENOG4108SXK	Transporter Drug Metabolite Exporter family
BI313_02940	ENOG4105D4A	Cell wall formation (By similarity)
BI313_02960	ENOG4105C26	Dehydrogenase
BI313_02995	ENOG4105W5Q	DNA repair protein (RadC
BI313_03015	ENOG4105E18	UPF0276 protein
BI313_03105	ENOG4105C8Q	Methyl-accepting chemotaxis
BI313_03115	ENOG4105CND	Glycosyl transferase, family 2
BI313_03120	ENOG4107BJW	polysaccharide deacetylase
BI313_03155	ENOG4105CMM	transposase
BI313_03200	ENOG4105CMM	transposase
BI313_03210	ENOG4108606	TspO/MBR family
BI313_03235	ENOG4105D98	threonine synthase
BI313_03245	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
BI313_03250	ENOG4105CUT	histidyl-tRNA synthetase
BI313_03260	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
BI313_03265	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
BI313_03270	ENOG4105CIH	Imidazole acetol-phosphate transaminase
BI313_03275	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
BI313_03280	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
BI313_03285	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
BI313_03290	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
BI313_03295	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
BI313_03315	ENOG4106YVY	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) (By similarity)
BI313_03320	ENOG4108CAF	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity)
BI313_03325	ENOG4107QY0	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity)
BI313_03335	ENOG4105CUB	amino acid
BI313_03340	ENOG4105CUB	amino acid
BI313_03350	ENOG4108JQ1	Dehydrogenase
BI313_03355	ENOG4105CQB	FAD linked oxidase domain protein
BI313_03375	ENOG4105FUQ	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
BI313_03385	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
BI313_03395	ENOG4108VUG	Enoyl-CoA hydratase
BI313_03405	ENOG4105CE1	Ferrous iron transport protein b
BI313_03420	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
BI313_03425	ENOG4108RPX	mosc domain containing protein
BI313_03430	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
BI313_03435	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
BI313_03445	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
BI313_03450	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
BI313_03460	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
BI313_03475	ENOG4105DY9	regulatoR
BI313_03480	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
BI313_03485	ENOG4105CRK	lysyL-tRNA synthetase
BI313_03490	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
BI313_03495	ENOG4105BZU	Histidine kinase
BI313_03500	ENOG4105BZU	Histidine kinase
BI313_03505	ENOG4105E39	Enoyl-CoA hydratase
BI313_03510	ENOG4105CEY	Amp-dependent synthetase and ligase
BI313_03520	ENOG4107QM5	aconitate hydratase
BI313_03535	ENOG4107QIJ	Aconitate hydratase 2
BI313_03540	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
BI313_03545	ENOG4105BZU	Histidine kinase
BI313_03550	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
BI313_03555	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
BI313_03560	ENOG4105BZU	Histidine kinase
BI313_03565	ENOG4105C8Q	Methyl-accepting chemotaxis
BI313_03575	ENOG4108V3W	Chemotaxis protein, CheW
BI313_03590	ENOG4105C8Q	Methyl-accepting chemotaxis
BI313_03595	ENOG4105C8Q	Methyl-accepting chemotaxis
BI313_03600	ENOG4105C8Q	Methyl-accepting chemotaxis
BI313_03610	ENOG4105C8Q	Methyl-accepting chemotaxis
BI313_03630	ENOG4105C8Q	Methyl-accepting chemotaxis
BI313_03645	ENOG4105CBS	Chea signal transduction histidine kinase
BI313_03650	ENOG4108VYJ	response regulator receiver protein
BI313_03660	ENOG4108V3W	Chemotaxis protein, CheW
BI313_03665	ENOG4107QJE	Chromosome Partitioning Protein
BI313_03670	ENOG4106VK6	Flagellar motor protein
BI313_03675	ENOG4105E14	MotA TolQ exbB proton channel
BI313_03755	ENOG4105CBS	Chea signal transduction histidine kinase
BI313_03765	ENOG4108VYJ	response regulator receiver protein
BI313_03770	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
BI313_03775	ENOG4107R21	site-determining protein
BI313_03780	ENOG4105FZW	flagellar biosynthesis regulator FlhF
BI313_03785	ENOG4105D7B	Flagellar biosynthesis protein flha
BI313_03790	ENOG4105D00	flagellar biosynthetic protein flhB
BI313_03795	ENOG4105BZU	Histidine kinase
BI313_03800	ENOG4105BZU	Histidine kinase
BI313_03805	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
BI313_03810	ENOG4105VS8	Flagellar biosynthetic protein fliq
BI313_03815	ENOG4105CN7	Flagellar biosynthetic protein FliP
BI313_03820	ENOG4105VTB	flagellar biosynthesis protein fliO
BI313_03825	ENOG4105DD5	Flagellar motor switch protein
BI313_03830	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
BI313_03850	ENOG4108JIR	Flagellum-specific ATP synthase
BI313_03860	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
BI313_03865	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
BI313_03870	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
BI313_03885	ENOG4107RGC	Glycosyl transferase, family 2
BI313_03930	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
BI313_03945	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
BI313_03950	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
BI313_03955	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
BI313_03975	ENOG4105MQ3	flagellar protein FliS
BI313_03980	ENOG4107W9T	flagellar hook-associated
BI313_03990	ENOG4105DTJ	flagellar hook-associated protein
BI313_04000	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
BI313_04010	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
BI313_04015	ENOG4105CGA	flagellar basal-body rod protein FlgG
BI313_04030	ENOG4108KPB	Flagellar basal-body rod protein FlgF
BI313_04035	ENOG4105BZE	flagellar hook protein, FlgE
BI313_04040	ENOG410822I	Flagellar hook capping protein
BI313_04045	ENOG4108ZC9	flagellar basal-body rod protein flgc
BI313_04050	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
BI313_04055	ENOG4107R88	Chemotaxis protein (CheV)
BI313_04075	ENOG4105BZU	Histidine kinase
BI313_04080	ENOG4105BZU	Histidine kinase
BI313_04090	ENOG4105BZU	Histidine kinase
BI313_04115	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
BI313_04125	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
BI313_04130	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
BI313_04140	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
BI313_04155	ENOG4105C3M	thioredoxin reductase
BI313_04160	ENOG4105CNU	cell division protein FtsK
BI313_04170	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
BI313_04175	ENOG4105D1H	recombination factor protein RarA
BI313_04180	ENOG41082MI	Protein CrcB homolog
BI313_04185	ENOG4105CHU	acetyl-coa acetyltransferase
BI313_04200	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
BI313_04205	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
BI313_04215	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
BI313_04225	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
BI313_04230	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
BI313_04235	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
BI313_04240	ENOG4105D06	uba thif-type nad fad binding protein
BI313_04255	ENOG4105CGK	Exodeoxyribonuclease III
BI313_04265	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
BI313_04270	ENOG41085AN	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
BI313_04280	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
BI313_04290	ENOG4105I5W	Transporter
BI313_04305	ENOG4108IFG	nitrite reductase, (NAD(P)H)
BI313_04310	ENOG4105KH3	nitrite reductase (NAD(P)h) small subunit
BI313_04320	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
BI313_04330	ENOG4108N8X	transition metal ion binding
BI313_04410	ENOG4105W39	Membrane
BI313_04420	ENOG4108RFG	Tetr family transcriptional regulator
BI313_04430	ENOG4106UW1	Major Facilitator superfamily
BI313_04435	ENOG4105EMU	Dehydrogenase
BI313_04460	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
BI313_04480	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
BI313_04485	ENOG4105EWI	Short-chain dehydrogenase reductase Sdr
BI313_04510	ENOG4105CHR	reductase
BI313_04515	ENOG4105ETT	transcriptional Regulator, LysR family
BI313_04530	ENOG4108X1T	PAAR repeat-containing protein
BI313_04705	ENOG4105YPM	F pilin acetylation protein TraX
BI313_04735	ENOG41090A4	Pterin carbinolamine dehydratase
BI313_04745	ENOG4105DUN	Mediates zinc uptake. May also transport other divalent cations (By similarity)
BI313_04755	ENOG4105EI2	Pseudouridine synthase
BI313_04760	ENOG4105C03	ribonuclease
BI313_04765	ENOG4105WH1	Two component transcriptional regulator luxr family
BI313_04780	ENOG4108V1T	peptidylprolyl cis-trans isomerase
BI313_04790	ENOG4107QQG	Dehydrogenase
BI313_04835	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
BI313_04840	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
BI313_04845	ENOG4105BZ1	(ABC) transporter
BI313_04860	ENOG4108EC8	DNA internalization-related competence protein ComEC
BI313_04880	ENOG4105D60	lipoprotein releasing system transmembrane protein
BI313_04890	ENOG410681N	tpr repeat protein
BI313_04915	ENOG410612Q	succinate dehydrogenase (cytochrome b-556 subunit)
BI313_04925	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
BI313_04940	ENOG4105CHC	glucokinase (EC 2.7.1.2)
BI313_04945	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
BI313_04950	ENOG4105C01	Dihydroxy-acid dehydratase
BI313_04955	ENOG4108UHU	Aldolase
BI313_04980	ENOG4105N7H	Cytochrome
BI313_05020	ENOG4105BZU	Histidine kinase
BI313_05025	ENOG4105BZM	domain protein
BI313_05050	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
BI313_05060	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
BI313_05080	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
BI313_05095	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
BI313_05100	ENOG4108Z6B	deaminase
BI313_05105	ENOG4105KST	dependent repressor
BI313_05110	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
BI313_05135	ENOG4107SFI	Major Facilitator superfamily
BI313_05150	ENOG4105CHJ	isochorismatase hydrolase
BI313_05160	ENOG4105ENE	Histidine kinase
BI313_05165	ENOG4105WH1	Two component transcriptional regulator luxr family
BI313_05180	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
BI313_05185	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
BI313_05190	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
BI313_05205	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
BI313_05210	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
BI313_05220	ENOG4105ESV	Glycosyl transferase, family 4
BI313_05225	ENOG4105CFV	Tetratricopeptide repeat protein
BI313_05235	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
BI313_05240	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
BI313_05245	ENOG4105CAT	Cytidine monophosphate kinase
BI313_05250	ENOG4105YK5	50S ribosomal protein L36
BI313_05260	ENOG4105DWY	Agmatine deiminase
BI313_05290	ENOG4105DRS	transport system, permease
BI313_05295	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
BI313_05300	ENOG4105XN3	extracellular solute-binding protein family 1
BI313_05325	ENOG4105K9H	YciI-like protein
BI313_05330	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
BI313_05335	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
BI313_05340	ENOG4105FE9	pseudouridine synthase
BI313_05355	ENOG4105CZ7	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
BI313_05365	ENOG4105CHM	Aminotransferase
BI313_05370	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
BI313_05375	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
BI313_05380	ENOG41060IM	Heme exporter protein
BI313_05390	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
BI313_05395	ENOG4105DA4	cytochrome c-type biogenesis protein
BI313_05405	ENOG4105KWW	Biogenesis protein
BI313_05410	ENOG4108M1T	Cytochrome c-type biogenesis protein
BI313_05425	ENOG4105DWV	Homoserine O-trans-acetylase
BI313_05435	ENOG4108JJ8	(ABC) transporter
BI313_05440	ENOG4108JJ9	ABC, transporter
BI313_05445	ENOG4105C4M	(Ubiquinol oxidase) subunit I
BI313_05450	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
BI313_05475	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
BI313_05495	ENOG4105CH7	arginosuccinase
BI313_05510	ENOG4105CAS	nag kinase
BI313_05525	ENOG4105CDH	Citrulline--aspartate ligase
BI313_05535	ENOG4105DBV	ornithine carbamoyltransferase
BI313_05545	ENOG4105C8N	cysteinyl-tRNA synthetase
BI313_05550	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
BI313_05560	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BI313_05570	ENOG4105CD3	dihydroorotase
BI313_05585	ENOG4105CPD	ethanolamine ammonia-lyase
BI313_05590	ENOG4107FQ9	ethanolamine ammonia-lyase
BI313_05625	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
BI313_05630	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
BI313_05635	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
BI313_05645	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
BI313_05650	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
BI313_05655	ENOG4105BZU	Histidine kinase
BI313_05670	ENOG4105ECY	inositol monophosphatase
BI313_05675	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
BI313_05690	ENOG4105C5H	ABC transporter
BI313_05695	ENOG4105C1J	atp-dependent rna helicase
BI313_05705	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
BI313_05710	ENOG4105CNG	UPF0061 protein
BI313_05720	ENOG4108RXX	maleylacetoacetate isomerase
BI313_05725	ENOG4105VEQ	Cold shock protein
BI313_05735	ENOG4108VWS	Yaeq family
BI313_05740	ENOG4105CBX	hi0933 family
BI313_05750	ENOG4105D0M	Protease HtpX homolog
BI313_05755	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
BI313_05760	ENOG4105CHR	reductase
BI313_05780	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
BI313_05785	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
BI313_05795	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
BI313_05800	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
BI313_05815	ENOG4105E6M	Sulphatase-modifying factor protein
BI313_05830	ENOG4105DQE	DNA ligase
BI313_05850	ENOG4105DFP	Integrase
BI313_05870	ENOG4105CMM	transposase
BI313_05900	ENOG4108V3W	Chemotaxis protein, CheW
BI313_05905	ENOG4105C8Q	Methyl-accepting chemotaxis
BI313_05915	ENOG4107QRT	dEAD DEAH box helicase
BI313_05930	ENOG4105KB2	stringent starvation protein b
BI313_05935	ENOG4107MKT	Stringent starvation protein a
BI313_05940	ENOG4105EIX	cytochrome c1
BI313_05950	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
BI313_05955	ENOG4105E4C	Lytic transglycosylase catalytic
BI313_05975	ENOG4105C9A	Phoh family
BI313_05985	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
BI313_05995	ENOG4108JU5	Magnesium and cobalt efflux protein
BI313_06020	ENOG4105D38	putrescine abc transporter
BI313_06025	ENOG4105F38	ABC transporter, permease
BI313_06030	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
BI313_06050	ENOG4107RUE	extracellular solute-binding protein family 1
BI313_06055	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
BI313_06075	ENOG4105CFQ	glutamine synthetase
BI313_06080	ENOG4105CJP	fad dependent oxidoreductase
BI313_06085	ENOG4105BZU	Histidine kinase
BI313_06095	ENOG4105W3S	hemerythrin-like, metal-binding protein
BI313_06100	ENOG4105CSH	Transporter
BI313_06115	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
BI313_06120	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
BI313_06125	ENOG4105FCD	Major Facilitator
BI313_06140	ENOG4106BRA	Membrane
BI313_06145	ENOG4105BZU	Histidine kinase
BI313_06150	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
BI313_06155	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
BI313_06170	ENOG4105C7I	Dehydrogenase
BI313_06180	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
BI313_06185	ENOG4105BZS	acriflavin resistance protein
BI313_06200	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
BI313_06205	ENOG4105DE4	1-phosphofructokinase
BI313_06210	ENOG4105DM4	PTS System
BI313_06230	ENOG4105CMM	transposase
BI313_06255	ENOG4107QT7	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
BI313_06260	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
BI313_06265	ENOG4105VIE	preprotein translocase, subunit YajC
BI313_06270	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
BI313_06275	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
BI313_06310	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
BI313_06315	ENOG4105E08	Glycoside hydrolase, family 9
BI313_06320	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
BI313_06325	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
BI313_06340	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
BI313_06345	ENOG4106H78	methyltransferase
BI313_06350	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
BI313_06400	ENOG4107QTZ	amino acid
BI313_06420	ENOG4105DC7	peptidase M24
BI313_06430	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
BI313_06445	ENOG41080HI	glycine oxidase
BI313_06450	ENOG4105CTU	Proline racemase
BI313_06460	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
BI313_06470	ENOG4105CEN	a g-specific adenine glycosylase
BI313_06475	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
BI313_06525	ENOG4105CSU	acyl-Coa dehydrogenase
BI313_06535	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
BI313_06555	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
BI313_06565	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
BI313_06595	ENOG4108NQK	Catalyzes the transfer of a glucuronic acid (GlcA) residue from UDP-glucuronate to mannose-alpha-1,3-glucose-beta- 1,4-glucose-P-P-polyisoprenyl to form the lipid-linked tetrasaccharide GlcA-Man-Glc(2)-PP-Pol, with a glucuronic acid- beta-mannose linkage. Is involved in the biosynthesis of the exopolysaccharide xanthan, since it catalyzes the fourth glycosylation step in the assembly of the pentasaccharide-P-P- polyisoprenyl repeating unit of xanthan. Is unable to use the trisaccharide acceptor freed from the pyrophosphate lipid moiety. Does not show specificity for the lipidic portion of the acceptor. Shows diminished activity when tested with 6-O-acetyl-mannose- alpha-1,3-glucose-beta-1,4-glucose-P-P-polyisoprenyl, a
BI313_06605	ENOG4107Y2G	Glycosyl transferase (Group 1
BI313_06610	ENOG4107UFF	group 1 glycosyl transferase
BI313_06630	ENOG4105D3Q	Sugar transferase
BI313_06650	ENOG4105WJX	transcriptional regulator MERR family
BI313_06655	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
BI313_06660	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
BI313_06665	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
BI313_06670	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
BI313_06675	ENOG41082NX	50s ribosomal protein l35
BI313_06680	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
BI313_06685	ENOG4105C22	threonyL-tRNA synthetase
BI313_06690	ENOG4105ETE	Transcriptional regulator (LacI family
BI313_06700	ENOG4107RBJ	symporter
BI313_06725	ENOG4105CG3	alpha amylase, catalytic region
BI313_06735	ENOG4106E4H	Type IV secretory pathway VirB3 family protein
BI313_06755	ENOG4105CMA	conjugation trbi family protein
BI313_06810	ENOG4105CWU	Biogenesis protein
BI313_06830	ENOG4105VWV	general secretion pathway protein h
BI313_06835	ENOG4105EWT	decarboxylase family
BI313_06840	ENOG4108KPZ	tonB-dependent Receptor
BI313_06845	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
BI313_06855	ENOG4105M2J	Glutaredoxin
BI313_06860	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
BI313_06865	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
BI313_06870	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
BI313_06880	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
BI313_06895	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
BI313_06900	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
BI313_06905	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
BI313_06910	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
BI313_06915	ENOG4105CHV	Transcription elongation factor NusA
BI313_06920	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
BI313_06930	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
BI313_06935	ENOG4105C8S	subunit m
BI313_06950	ENOG4105DF2	NADH dehydrogenase subunit j
BI313_06955	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
BI313_06960	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
BI313_06965	ENOG4108IEH	NADH dehydrogenase subunit g
BI313_06970	ENOG4107QIZ	NADH dehydrogenase
BI313_06975	ENOG4105GKE	subunit e
BI313_06980	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
BI313_06985	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
BI313_06995	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
BI313_07010	ENOG4105CP7	Triose-phosphate isomerase
BI313_07030	ENOG4105BZU	Histidine kinase
BI313_07050	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
BI313_07070	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
BI313_07080	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
BI313_07085	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
BI313_07100	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
BI313_07105	ENOG4105C5I	Dehydrogenase
BI313_07110	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
BI313_07120	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
BI313_07130	ENOG4105DJ4	phosphatidylserine decarboxylase
BI313_07140	ENOG4106770	Is able to cleave peptidoglycan (By similarity)
BI313_07145	ENOG4105D7A	ATP-binding protein
BI313_07155	ENOG4107VIJ	nudix hydrolase
BI313_07170	ENOG4108RRZ	Transcription elongation factor GreB
BI313_07175	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
BI313_07200	ENOG4105DHP	deoxycytidine triphosphate deaminase
BI313_07210	ENOG4105D1F	ATP-binding protein
BI313_07225	ENOG4105C9K	Endothelin-converting enzyme 1
BI313_07230	ENOG4105C9K	Endothelin-converting enzyme 1
BI313_07250	ENOG4105DC8	reductase
BI313_07255	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
BI313_07265	ENOG4108YZY	peptidylprolyl cis-trans isomerase
BI313_07270	ENOG4105K4H	Nlp p60 protein
BI313_07275	ENOG4105K4H	Nlp p60 protein
BI313_07300	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
BI313_07305	ENOG4105BZU	Histidine kinase
BI313_07325	ENOG4105CK2	sodium dicarboxylate symporter
BI313_07330	ENOG4105G6Z	alkaline phosphatase
BI313_07335	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
BI313_07340	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
BI313_07345	ENOG4105CTB	Polyprenyl synthetase
BI313_07365	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
BI313_07370	ENOG4105N42	UPF0307 protein
BI313_07375	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
BI313_07390	ENOG4105C03	ribonuclease
BI313_07395	ENOG4108Z03	MAF-like protein
BI313_07400	ENOG4105MPN	Membrane
BI313_07415	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
BI313_07430	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
BI313_07445	ENOG4105C8T	Leucyl-tRNA synthetase
BI313_07455	ENOG4107QR8	Thioredoxin
BI313_07465	ENOG4105WG9	Conserved Protein
BI313_07520	ENOG4105BZ1	(ABC) transporter
BI313_07540	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
BI313_07570	ENOG4105BZU	Histidine kinase
BI313_07575	ENOG4105FE9	pseudouridine synthase
BI313_07580	ENOG4105BZU	Histidine kinase
BI313_07600	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
BI313_07660	ENOG4105UGU	tonB-dependent Receptor
BI313_07695	ENOG4105CPC	Aldo Keto reductase
BI313_07700	ENOG4105F27	Major Facilitator
BI313_07705	ENOG4105EJC	lysr family transcriptional regulator
BI313_07715	ENOG4105CF7	AraC family transcriptional regulator
BI313_07725	ENOG4105EQ2	LysR family Transcriptional regulator
BI313_07730	ENOG4105CPC	Aldo Keto reductase
BI313_07735	ENOG4108JGH	Tetr family transcriptional regulator
BI313_07740	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
BI313_07745	ENOG4105BZS	acriflavin resistance protein
BI313_07750	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
BI313_07760	ENOG4105MYN	Zinc uptake regulation protein
BI313_07790	ENOG4105CT7	inner membrane cred family protein
BI313_07795	ENOG4105EB3	Histidine kinase
BI313_07800	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
BI313_07805	ENOG4105D6S	protein involved in catabolism of external DNA
BI313_07825	ENOG4108JA2	transcriptioN-repair coupling factor
BI313_07835	ENOG4105CBS	Chea signal transduction histidine kinase
BI313_07840	ENOG4105C8Q	Methyl-accepting chemotaxis
BI313_07845	ENOG4108V3W	Chemotaxis protein, CheW
BI313_07850	ENOG4105BZU	Histidine kinase
BI313_07855	ENOG4105BZU	Histidine kinase
BI313_07860	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
BI313_07870	ENOG4107RZC	phospholipase d
BI313_07875	ENOG4105C9K	Endothelin-converting enzyme 1
BI313_07885	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
BI313_07890	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
BI313_07905	ENOG4105EUB	pirin domain protein
BI313_07920	ENOG4105EUB	pirin domain protein
BI313_07925	ENOG4105D22	carbon starvation protein
BI313_07930	ENOG4105VCD	cytoplasmic protein
BI313_07975	ENOG4107XAN	XdhC and CoxI family
BI313_07980	ENOG4105C7W	Xanthine dehydrogenase
BI313_07990	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
BI313_08005	ENOG4108UUM	single-stranded DNA-binding protein
BI313_08010	ENOG4105EAH	synthase
BI313_08020	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
BI313_08035	ENOG4105CFH	Aspartokinase
BI313_08040	ENOG4107ZY0	Phenazine biosynthesis-like protein
BI313_08045	ENOG4105JAB	phenazine biosynthesis protein, phzf family
BI313_08055	ENOG4108Z9K	Osmotically inducible protein
BI313_08060	ENOG4105CXT	aspartate transcarbamylase
BI313_08065	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
BI313_08070	ENOG4108UJU	UPF0301 protein
BI313_08075	ENOG4108MAJ	Membrane
BI313_08080	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
BI313_08100	ENOG4105CZX	twitching motility protein
BI313_08110	ENOG4105DFA	alanine racemase domain protein
BI313_08115	ENOG4105II7	pyrroline-5-carboxylate reductase
BI313_08150	ENOG4108Z0Z	intracellular protease Pfpi family
BI313_08170	ENOG4105C3K	feS assembly ATPase SufC
BI313_08175	ENOG4105JRK	feS assembly protein SufD
BI313_08180	ENOG4105C9B	Cysteine desulfurase
BI313_08190	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
BI313_08200	ENOG4108ESX	Receptor
BI313_08235	ENOG4105CJ2	(LipO)protein
BI313_08250	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
BI313_08255	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
BI313_08265	ENOG4105EHM	Aminoglycoside phosphotransferase
BI313_08270	ENOG4108S0S	Nucleotidyl transferase
BI313_08280	ENOG4105C02	permease
BI313_08290	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
BI313_08305	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
BI313_08340	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
BI313_08350	ENOG4105C2X	Arabinose 5-phosphate isomerase
BI313_08355	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
BI313_08365	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
BI313_08370	ENOG4108IUZ	ABC transporter
BI313_08375	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
BI313_08380	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
BI313_08385	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
BI313_08390	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
BI313_08395	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
BI313_08405	ENOG41080Z8	PHOSPHOCARRIER protein
BI313_08410	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
BI313_08415	ENOG4105CJW	magnesium transporter
BI313_08420	ENOG4107UWA	esterase
BI313_08425	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
BI313_08430	ENOG4105C4M	(Ubiquinol oxidase) subunit I
BI313_08435	ENOG4105C85	amino acid
BI313_08440	ENOG4108NFF	pectate lyase
BI313_08455	ENOG4105CUB	amino acid
BI313_08460	ENOG4108MHS	Lysyl endopeptidase
BI313_08500	ENOG4108Z4X	TRANSCRIPTIONal
BI313_08510	ENOG4106032	Glutathionylspermidine synthase
BI313_08535	ENOG4108P9J	Phage shock protein A
BI313_08550	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
BI313_08555	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
BI313_08570	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
BI313_08575	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
BI313_08580	ENOG4105BZU	Histidine kinase
BI313_08585	ENOG4105BZU	Histidine kinase
BI313_08590	ENOG4105BZU	Histidine kinase
BI313_08595	ENOG4108YYC	ycei family
BI313_08610	ENOG4105VEQ	Cold shock protein
BI313_08625	ENOG4105EJQ	L-serine dehydratase
BI313_08635	ENOG4105CFH	Aspartokinase
BI313_08640	ENOG4105C28	cystathionine
BI313_08645	ENOG4106TYC	homoserine o-acetyltransferase (EC 2.3.1.31)
BI313_08650	ENOG4105DR5	peptidase
BI313_08655	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
BI313_08660	ENOG4108UT2	hemolysin iii
BI313_08665	ENOG41066T0	asmA family
BI313_08670	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
BI313_08680	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
BI313_08685	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
BI313_08695	ENOG4105D05	Receptor
BI313_08700	ENOG4108IG5	Transcriptional regulator
BI313_08710	ENOG4107QPN	acyl-Coa dehydrogenase
BI313_08740	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
BI313_08745	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
BI313_08755	ENOG4107QX8	SPFH domain, Band 7 family protein
BI313_08765	ENOG4105DXN	mazG family
BI313_08770	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
BI313_08775	ENOG4107RK2	ADP-ribose diphosphatase NudE
BI313_08785	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
BI313_08805	ENOG4105VRS	hydrolase family 18
BI313_08810	ENOG4105E2D	ec 3.2.1.52
BI313_08830	ENOG4105CWX	Alpha-1,2-mannosidase
BI313_08870	ENOG4106N3A	copper homeostasis protein cutc
BI313_08880	ENOG4105CP2	von willebrand factor, type a
BI313_08895	ENOG4105D9U	N-acetyltransferase
BI313_08910	ENOG4105CBS	Chea signal transduction histidine kinase
BI313_08915	ENOG4105C8Q	Methyl-accepting chemotaxis
BI313_08920	ENOG410807Z	Modulation of CheA activity in response to attractants (Chemotaxis
BI313_08925	ENOG4105M3Z	response regulator
BI313_08930	ENOG4108UNF	response regulator
BI313_08935	ENOG4105D7Z	glutathione synthase
BI313_08945	ENOG41065RQ	ADP-ribosylation crystallin J1
BI313_08950	ENOG41072GX	Peptidase M22 Glycoprotease
BI313_08955	ENOG4105DVT	helicase
BI313_08965	ENOG4105BZ4	penicillin-binding protein
BI313_08970	ENOG4107S6X	Glycosyl transferase, family 2
BI313_08980	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
BI313_08985	ENOG410698T	Required for coenzyme pyrroloquinoline quinone (PQQ) biosynthesis. PQQ is probably formed by cross-linking a specific glutamate to a specific tyrosine residue and excising these residues from the peptide (By similarity)
BI313_08990	ENOG4105JIE	May be involved in the transport of PQQ or its precursor to the periplasm (By similarity)
BI313_08995	ENOG41086XE	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ (By similarity)
BI313_09020	ENOG4105CHC	glucokinase (EC 2.7.1.2)
BI313_09030	ENOG4105CQ7	ATP-dependent helicase
BI313_09040	ENOG4105C9U	ATP-dependent DNA helicase RecQ
BI313_09070	ENOG4105C8Q	Methyl-accepting chemotaxis
BI313_09080	ENOG4105BZU	Histidine kinase
BI313_09100	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
BI313_09110	ENOG4105KCK	Peptidoglycan-associated lipoprotein
BI313_09115	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
BI313_09125	ENOG4105M8F	Biopolymer transport protein exbD tolR
BI313_09130	ENOG4105E02	MotA TolQ exbB proton channel
BI313_09135	ENOG4107YD3	Thioesterase
BI313_09140	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
BI313_09150	ENOG4105DFH	Transport of potassium into the cell (By similarity)
BI313_09155	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
BI313_09180	ENOG4105C9M	aspartyl-trna synthetase
BI313_09200	ENOG4108ISG	Major Facilitator
BI313_09220	ENOG41080HT	Transcriptional regulator, arsr family
BI313_09225	ENOG4108VCT	Sulfite exporter TauE/SafE
BI313_09240	ENOG4105HSS	phospholipase C
BI313_09260	ENOG4105ETT	transcriptional Regulator, LysR family
BI313_09265	ENOG4105CVE	Lytic murein transglycosylase
BI313_09275	ENOG4105C5H	ABC transporter
BI313_09280	ENOG4107RNH	Outer membrane receptor FepA
BI313_09290	ENOG4107RNH	Outer membrane receptor FepA
BI313_09295	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
BI313_09310	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
BI313_09315	ENOG4105CNV	Aldolase
BI313_09320	ENOG4105GAV	receptor
BI313_09335	ENOG4105C6X	Major Facilitator
BI313_09340	ENOG4105DBM	Siderophore biosynthesis protein
BI313_09345	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
BI313_09365	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
BI313_09370	ENOG4108YZT	Adenosylcobinamide kinase
BI313_09375	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
BI313_09380	ENOG4105EFT	decarboxylase
BI313_09385	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
BI313_09390	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
BI313_09405	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
BI313_09415	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
BI313_09420	ENOG41082IR	Excinuclease ABC C subunit domain protein
BI313_09455	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
BI313_09460	ENOG4108K4C	ec 3.1.3.12
BI313_09465	ENOG4105BZP	glycoside hydrolase 15-related
BI313_09470	ENOG4105C1K	alpha-alpha-trehalose-phosphate synthase
BI313_09475	ENOG4105DZG	Dehydrogenase
BI313_09480	ENOG4105C8Q	Methyl-accepting chemotaxis
BI313_09485	ENOG4105KIR	Thiol-disulfide oxidoreductase dcc
BI313_09500	ENOG4105C34	Pseudouridine synthase
BI313_09505	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BI313_09515	ENOG4105C4K	Nad synthetase
BI313_09525	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
BI313_09530	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
BI313_09535	ENOG4107TUY	Histidine kinase
BI313_09540	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
BI313_09545	ENOG4107QHF	type ii secretion system protein e
BI313_09585	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
BI313_09590	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
BI313_09595	ENOG4105BZU	Histidine kinase
BI313_09600	ENOG4105ETX	regulatoR
BI313_09610	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
BI313_09645	ENOG4107QKA	exodeoxyribonuclease V beta
BI313_09735	ENOG4105D9P	serine threonine protein kinase
BI313_09740	ENOG4105D9P	serine threonine protein kinase
BI313_09865	ENOG4105W5Q	DNA repair protein (RadC
BI313_09940	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
BI313_09945	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
BI313_09970	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
BI313_09980	ENOG4105ETE	Transcriptional regulator (LacI family
BI313_09995	ENOG41065HY	1,4-beta-cellobiosidase
BI313_10015	ENOG4105EBR	Carboxylesterase
BI313_10020	ENOG4105C2N	RNA methyltransferase TrmH family group 3
BI313_10025	ENOG4105BZG	amino acid carrier protein
BI313_10040	ENOG4105BZS	acriflavin resistance protein
BI313_10045	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
BI313_10050	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
BI313_10055	ENOG4105C11	sulfate adenylyltransferase), subunit 2
BI313_10060	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
BI313_10065	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
BI313_10090	ENOG4105BZU	Histidine kinase
BI313_10100	ENOG4107R11	Transcriptional regulator
BI313_10105	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
BI313_10120	ENOG4108UVJ	appr-1-p processing domain protein
BI313_10125	ENOG4107R1Y	fructose-bisphosphate aldolase
BI313_10135	ENOG4105CA9	Pyruvate kinase
BI313_10145	ENOG4105BZA	Phosphoglycerate kinase
BI313_10165	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
BI313_10185	ENOG4105EIF	outer membrane protein W
BI313_10195	ENOG4107S76	domain protein
BI313_10200	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
BI313_10205	ENOG4105E0C	molybdate abc transporter
BI313_10210	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
BI313_10225	ENOG4105NA0	Transcriptional regulator
BI313_10245	ENOG4107Y2H	ErfK ybiS ycfS ynhG family protein
BI313_10250	ENOG4105DR5	peptidase
BI313_10260	ENOG4105CHR	reductase
BI313_10265	ENOG4105CBN	LysR family transcriptional regulator
BI313_10270	ENOG4105CNM	Receptor
BI313_10275	ENOG4105CV1	Transketolase (EC 2.2.1.1)
BI313_10280	ENOG4105CK2	sodium dicarboxylate symporter
BI313_10290	ENOG4107QVM	von Willebrand factor, type A
BI313_10310	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
BI313_10315	ENOG4105E4G	Type IV pilus
BI313_10340	ENOG4108JQC	penicillin-binding protein 1A
BI313_10355	ENOG4105NRA	50s ribosomal protein l31 type b
BI313_10360	ENOG4105DU0	nucleoside hydrolase
BI313_10365	ENOG4105CB5	ATP-dependent DNA helicase recG
BI313_10370	ENOG4105KME	endoribonuclease L-psp
BI313_10375	ENOG4105CTX	dehydratase
BI313_10390	ENOG4105DJB	Major Facilitator Superfamily
BI313_10405	ENOG4107RSM	transcriptional regulator
BI313_10415	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
BI313_10420	ENOG4107YBY	Hydrolase
BI313_10425	ENOG4105DKT	Transcriptional regulator
BI313_10435	ENOG4105TW1	Carbohydrate-selective porin OprB
BI313_10450	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
BI313_10455	ENOG4105CHR	reductase
BI313_10465	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
BI313_10470	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
BI313_10475	ENOG4105DSJ	YicC domain protein
BI313_10480	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
BI313_10490	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
BI313_10495	ENOG4105CSA	Coproporphyrinogen iii oxidase
BI313_10510	ENOG4105D9Y	Splits dipeptides with a prolyl residue in the C- terminal position (By similarity)
BI313_10525	ENOG4107RAQ	aminopeptidase
BI313_10540	ENOG4105W8B	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
BI313_10550	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
BI313_10570	ENOG41063JG	Transcriptional regulator
BI313_10575	ENOG4105VCQ	rubredoxin
BI313_10580	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
BI313_10595	ENOG4105FTC	Lytic transglycosylase catalytic
BI313_10615	ENOG4105K44	type iii secretion
BI313_10630	ENOG4108JIR	Flagellum-specific ATP synthase
BI313_10645	ENOG4107Y59	type iii secretion
BI313_10665	ENOG4108HR8	type iii secretion
BI313_10685	ENOG4105VS8	Flagellar biosynthetic protein fliq
BI313_10790	ENOG4105CMM	transposase
BI313_10800	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
BI313_10815	ENOG4105CIH	Imidazole acetol-phosphate transaminase
BI313_10845	ENOG4105C8Y	Acetylornithine aminotransferase
BI313_10850	ENOG4105EYW	Ion transport protein
BI313_10880	ENOG410841Q	phosphoesterase PA-phosphatase related protein
BI313_10885	ENOG4105FFC	UPF0187 protein
BI313_10895	ENOG4105DFU	Cell wall formation (By similarity)
BI313_10900	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
BI313_11020	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
BI313_11030	ENOG4105F0N	pyrophosphate phospho-hydrolase
BI313_11045	ENOG4105ECQ	AraC Family Transcriptional Regulator
BI313_11050	ENOG4108M3R	transcriptional activator CadC
BI313_11055	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
BI313_11090	ENOG4105C7B	Threonine dehydratase
BI313_11095	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
BI313_11105	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
BI313_11110	ENOG4105F2W	methyltransferase
BI313_11115	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
BI313_11120	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
BI313_11125	ENOG4108MP6	LysR family Transcriptional regulator
BI313_11130	ENOG4105BZU	Histidine kinase
BI313_11140	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
BI313_11145	ENOG4105DFG	type I secretion outer membrane protein
BI313_11155	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
BI313_11160	ENOG4105D1S	lipid A biosynthesis
BI313_11185	ENOG4105C6K	Malic enzyme
BI313_11210	ENOG4105CPC	Aldo Keto reductase
BI313_11225	ENOG4105WH1	Two component transcriptional regulator luxr family
BI313_11230	ENOG4106JDA	Phosphoglycerate transport regulatory protein PGTC
BI313_11235	ENOG4105DHQ	Histidine kinase
BI313_11250	ENOG4105D4T	Citrate transporter
BI313_11255	ENOG4105CHR	reductase
BI313_11260	ENOG4105ETE	Transcriptional regulator (LacI family
BI313_11275	ENOG4107QW3	Sucrose phosphorylase
BI313_11290	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
BI313_11295	ENOG4105CHM	Aminotransferase
BI313_11330	ENOG41069H0	dihydroorotase EC 3.5.2.3
BI313_11335	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
BI313_11375	ENOG4108RMV	DegV Family
BI313_11390	ENOG4108QBQ	Catalyzes the condensation of formaldehyde and glutathione to S-hydroxymethylglutathione (By similarity)
BI313_11405	ENOG4105DUM	transcriptional regulator, lysR family
BI313_11420	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
BI313_11425	ENOG4105JJR	Histidine kinase
BI313_11455	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
BI313_11460	ENOG4106RE7	Cytochrome
BI313_11470	ENOG4108Z33	Thiol disulfide Interchange Protein
BI313_11480	ENOG4105C94	Transporter
BI313_11485	ENOG4105C26	Dehydrogenase
BI313_11490	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
BI313_11540	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
BI313_11555	ENOG4105VFQ	Histone family protein nucleoid-structuring protein H-NS
BI313_11570	ENOG4105DHJ	ABC, transporter
BI313_11575	ENOG4108SNX	Mammalian cell entry related domain protein
BI313_11600	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
BI313_11615	ENOG4107QKV	phosphomannomutase
BI313_11620	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
BI313_11630	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
BI313_11635	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
BI313_11650	ENOG4105BZJ	Electron transfer flavoprotein
BI313_11655	ENOG4105C10	Electron transfer flavoprotein
BI313_11660	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
BI313_11665	ENOG4105CKK	Glycosyl transferase, family 2
BI313_11670	ENOG4105J5G	Transferase hexapeptide repeat containing protein
BI313_11700	ENOG4105EY8	ABC transporter
BI313_11710	ENOG4105C28	cystathionine
BI313_11735	ENOG4105CZX	twitching motility protein
BI313_11745	ENOG4108RXX	maleylacetoacetate isomerase
BI313_11760	ENOG4105C1J	atp-dependent rna helicase
BI313_11765	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
BI313_11795	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
BI313_11805	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
BI313_11825	ENOG4105DGW	oligopeptidase A
BI313_11885	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
BI313_11890	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
BI313_11895	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
BI313_11915	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
BI313_11930	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
BI313_11945	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
BI313_11950	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
BI313_11955	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
BI313_11965	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
BI313_11970	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
BI313_11975	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
BI313_11980	ENOG4107RAZ	it plays a direct role in the translocation of protons across the membrane (By similarity)
BI313_11995	ENOG4107QN2	dihydrolipoyl dehydrogenase
BI313_12005	ENOG4107QSN	dihydrolipoamide acetyltransferase
BI313_12030	ENOG4105D01	(LipO)protein
BI313_12035	ENOG4108UMI	ABC transporter, permease
BI313_12040	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
BI313_12045	ENOG4108EHX	EamA-like transporter family
BI313_12050	ENOG4108VPT	UPF0234 protein
BI313_12060	ENOG4105BZU	Histidine kinase
BI313_12075	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
BI313_12080	ENOG4107YBY	Hydrolase
BI313_12085	ENOG4105I08	Pseudouridine synthase
BI313_12090	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
BI313_12110	ENOG4105BZU	Histidine kinase
BI313_12130	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
BI313_12135	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
BI313_12140	ENOG4105EW9	transcriptional regulator AsnC family
BI313_12160	ENOG4107RD7	Flagellar Motor Protein, MotA
BI313_12165	ENOG4105ER2	Ompa motb domain protein
BI313_12190	ENOG4105E3A	(ABC) transporter
BI313_12195	ENOG4105DA5	(ABC) transporter
BI313_12200	ENOG4105EEQ	Na H antiporter
BI313_12225	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
BI313_12240	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
BI313_12245	ENOG4105EJC	lysr family transcriptional regulator
BI313_12255	ENOG4105CPC	Aldo Keto reductase
BI313_12265	ENOG4105C9K	Endothelin-converting enzyme 1
BI313_12285	ENOG4107QTZ	amino acid
BI313_12295	ENOG4108VAC	response regulator
BI313_12300	ENOG4108HRK	Histidine kinase
BI313_12315	ENOG4108Z9Z	response to DNA damage stimulus
BI313_12320	ENOG4105WEF	catalase
BI313_12335	ENOG4105BZU	Histidine kinase
BI313_12350	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
BI313_12370	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
BI313_12395	ENOG4105E2A	Dehydrogenase
BI313_12425	ENOG4105C7W	Xanthine dehydrogenase
BI313_12470	ENOG4105DA5	(ABC) transporter
BI313_12480	ENOG4108UQ8	endoribonuclease L-psp
BI313_12515	ENOG4105CMQ	Chloride channel
BI313_12525	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
BI313_12535	ENOG4105KVH	Transcriptional regulator
BI313_12555	ENOG4108W2Y	isochorismatase
BI313_12595	ENOG4107PBH	Toxic component of a toxin-antitoxin (TA) module. A
BI313_12610	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
BI313_12640	ENOG4107WZZ	SMC domain protein
BI313_12700	ENOG4105ESI	atpase involved in dna repair
BI313_12770	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
BI313_12775	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
BI313_12780	ENOG4105D1S	lipid A biosynthesis
BI313_12785	ENOG4108Z7F	N-acetyltransferase
BI313_12825	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
BI313_12830	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
BI313_12835	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
BI313_12840	ENOG4108WZM	domain protein
BI313_12845	ENOG4105C79	DNA protecting protein DprA
BI313_12850	ENOG4108RPN	Protein smg homolog
BI313_12865	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
BI313_12870	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
BI313_12885	ENOG4107ZQV	short-chain dehydrogenase reductase
BI313_12895	ENOG4105D07	Signal peptide peptidase, SppA
BI313_12900	ENOG4107QI1	Mate efflux family protein
BI313_12920	ENOG4105C25	Primosomal protein n'
BI313_12925	ENOG4108TGY	Glutathione S-transferase
BI313_12945	ENOG4105EN6	Membrane
BI313_12950	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
BI313_12955	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
BI313_12960	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
BI313_12965	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
BI313_12970	ENOG4105CAK	Cell division ATP-binding protein ftsE
BI313_12975	ENOG4105C1J	atp-dependent rna helicase
BI313_12980	ENOG4105K63	Thioredoxin
BI313_12985	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
BI313_12995	ENOG4105VS7	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity)
BI313_13000	ENOG4108PZW	LysR family Transcriptional regulator
BI313_13010	ENOG4105E9K	Isocitrate dehydrogenase
BI313_13020	ENOG4109066	lysm domain bon superfamily protein
BI313_13025	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
BI313_13030	ENOG4105CH2	amidohydrolase
BI313_13040	ENOG4105BZS	acriflavin resistance protein
BI313_13045	ENOG4105BZS	acriflavin resistance protein
BI313_13060	ENOG4105E32	cytoplasmic protein
BI313_13100	ENOG4108UQS	dipeptidase
BI313_13105	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
BI313_13115	ENOG4105DTQ	mandelate racemase muconate lactonizing
BI313_13125	ENOG4105D5Q	Arginine ornithine antiporter
BI313_13140	ENOG4108Z12	YiaAB two helix domain-containing protein
BI313_13150	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
BI313_13155	ENOG4107ZVW	dihydroneopterin aldolase
BI313_13160	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
BI313_13165	ENOG4105VCC	30S ribosomal protein S21
BI313_13170	ENOG4105KTH	gatB Yqey
BI313_13175	ENOG4107U9T	Pfam:Ribonuclease_BN
BI313_13180	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
BI313_13195	ENOG4105DHU	Bile acid
BI313_13205	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
BI313_13230	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
BI313_13235	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
BI313_13245	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
BI313_13255	ENOG4105C26	Dehydrogenase
BI313_13290	ENOG4105DR5	peptidase
BI313_13305	ENOG4105EYM	Major Facilitator superfamily
BI313_13315	ENOG4105CGK	Exodeoxyribonuclease III
BI313_13320	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
BI313_13330	ENOG4107QJE	Chromosome Partitioning Protein
BI313_13335	ENOG4105FA0	parb-like partition protein
BI313_13355	ENOG4105CKK	Glycosyl transferase, family 2
BI313_13375	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
BI313_13380	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
BI313_13390	ENOG4105C75	arginyL-tRNA synthetase
BI313_13405	ENOG4105EMU	Dehydrogenase
BI313_13410	ENOG4105EXC	Acyl-transferase
BI313_13430	ENOG4105CEY	Amp-dependent synthetase and ligase
BI313_13435	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
BI313_13440	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
BI313_13460	ENOG4105CPE	K01197 hyaluronoglucosaminidase EC 3.2.1.35
BI313_13470	ENOG4108YZA	Nitrogen regulatory protein pii
BI313_13475	ENOG4105W0Z	cytoplasmic protein
BI313_13480	ENOG4105C0P	Mg chelatase subunit ChlI
BI313_13495	ENOG41066DG	(EAL) domain protein
BI313_13510	ENOG4105EJ2	Transcriptional regulator
BI313_13525	ENOG4105E0Y	RtcB Protein
BI313_13565	ENOG4105ECP	epimerase
BI313_13570	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
BI313_13575	ENOG4105DHQ	Histidine kinase
BI313_13595	ENOG4105C0H	protease
BI313_13615	ENOG4105C02	permease
BI313_13625	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
BI313_13640	ENOG4107VGR	Catalase
BI313_13655	ENOG4108S01	response regulator
BI313_13665	ENOG4108ZGX	Histidine kinase
BI313_13670	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
BI313_13675	ENOG4105C19	ABC transporter
BI313_13700	ENOG4105FDR	Membrane
BI313_13720	ENOG4105C31	Tryptophanyl-tRNA synthetase
BI313_13725	ENOG4105VDW	Csbd family
BI313_13765	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
BI313_13785	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
BI313_13795	ENOG4105EXZ	Involved in the regulation of ptsG expression by binding and inactivating Mlc (By similarity)
BI313_13810	ENOG4105EB3	Histidine kinase
BI313_13815	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
BI313_13825	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
BI313_13845	ENOG4105CH6	catalase
BI313_13850	ENOG4105DVT	helicase
BI313_13865	ENOG4105E2X	shikimate dehydrogenase
BI313_13875	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
BI313_13880	ENOG4105D52	delta-aminolevulinic acid dehydratase
BI313_13915	ENOG4105CYM	Glutathione S-transferase
BI313_13935	ENOG4105QV4	Tryptophan halogenase
BI313_13950	ENOG4108IUW	ABC transporter
BI313_13960	ENOG4105VZ8	Transcriptional regulator
BI313_13985	ENOG4108JA0	Oxidoreductase, FAD NAD(P)-binding domain protein
BI313_13990	ENOG4105DA5	(ABC) transporter
BI313_13995	ENOG4105E3A	(ABC) transporter
BI313_14000	ENOG41063V1	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
BI313_14015	ENOG4105K63	Thioredoxin
BI313_14030	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
BI313_14035	ENOG4107QYD	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
BI313_14060	ENOG4105CD5	CoA-binding domain protein
BI313_14065	ENOG4105CJW	magnesium transporter
BI313_14070	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
BI313_14075	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
BI313_14080	ENOG4105BZP	glycoside hydrolase 15-related
BI313_14085	ENOG4107ZF2	Phosphatase
BI313_14100	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
BI313_14135	ENOG4105C2D	reductase
BI313_14160	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
BI313_14165	ENOG4105E9Q	Acyl-transferase
BI313_14175	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
BI313_14225	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
BI313_14230	ENOG4105C2M	dna polymerase I
BI313_14260	ENOG4107TPY	serine threonine protein kinase
BI313_14265	ENOG4108ZF3	Phosphatase
BI313_14280	ENOG4106VK6	Flagellar motor protein
BI313_14290	ENOG4107S5I	aldo keto reductase
BI313_14295	ENOG410642W	LysR family Transcriptional regulator
BI313_14315	ENOG4105CS6	Rhs element vgr protein
BI313_14345	ENOG4108RXX	maleylacetoacetate isomerase
BI313_14380	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
BI313_14410	ENOG4108WC9	type VI secretion system effector, hcp1 family
BI313_14440	ENOG4105C4R	Atp-dependent dna helicase
BI313_14455	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
BI313_14460	ENOG4108KB2	LysR family Transcriptional regulator
BI313_14465	ENOG4105JSC	dimethylmenaquinone methyltransferase
BI313_14475	ENOG4105KHM	amidohydrolase 2
BI313_14480	ENOG4105W0E	50S ribosomal protein L33
BI313_14485	ENOG4105KDC	50s ribosomal protein l28
BI313_14515	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
BI313_14560	ENOG41062QD	Membrane
BI313_14570	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
BI313_14600	ENOG4105DSG	hydrolase family 43
BI313_14615	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
BI313_14620	ENOG4105ERH	Fumarylacetoacetate hydrolase
BI313_14625	ENOG4105DIA	mandelate racemase muconate lactonizing
BI313_14630	ENOG4105QJH	Domain of unknown function (DUF718)
BI313_14635	ENOG4105EDR	glucose galactose transporter
BI313_14640	ENOG4108K2P	TRANSCRIPTIONal
BI313_14650	ENOG4105BZU	Histidine kinase
BI313_14665	ENOG4105E2V	Glycosyltransferase 36
BI313_14670	ENOG4105CT4	transporter
BI313_14675	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
BI313_14705	ENOG4105CFU	surface antigen
BI313_14710	ENOG4105D05	Receptor
BI313_14715	ENOG4107RDJ	Sulfotransferase
BI313_14725	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
BI313_14730	ENOG4107QHF	type ii secretion system protein e
BI313_14740	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
BI313_14755	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
BI313_14760	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
BI313_14775	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
BI313_14795	ENOG4105DH7	May be involved in recombination (By similarity)
BI313_14810	ENOG4105C93	Xylose Isomerase
BI313_14815	ENOG4105ETE	Transcriptional regulator (LacI family
BI313_14820	ENOG4105D0H	Alpha-glucuronidase (EC 3.2.1.139)
BI313_14830	ENOG4105CXK	mandelate racemase muconate lactonizing
BI313_14845	ENOG4105DEI	Mannitol dehydrogenase
BI313_14880	ENOG4105D9F	endo-1,4-beta-xylanase (EC 3.2.1.8)
BI313_14885	ENOG4105CNT	hydrolase family 2
BI313_14890	ENOG4105D2H	Uronic isomerase
BI313_14910	ENOG4105CT4	transporter
BI313_14915	ENOG4105DT9	hydrolase family 43
BI313_14955	ENOG4105E55	glycerol-3-phosphate acyltransferase
BI313_14965	ENOG4105ETE	Transcriptional regulator (LacI family
BI313_14980	ENOG4105QV4	Tryptophan halogenase
BI313_14985	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
BI313_14990	ENOG4105CUR	5'-nucleotidase, lipoprotein e(p4) family
BI313_14995	ENOG4108YXG	UPF0502 protein
BI313_15010	ENOG4105C4R	Atp-dependent dna helicase
BI313_15015	ENOG4107104	thymidine kinase
BI313_15020	ENOG4105BZU	Histidine kinase
BI313_15025	ENOG4105DJ9	glucan biosynthesis protein
BI313_15035	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
BI313_15065	ENOG4105DKK	Benzoate
BI313_15085	ENOG4105DSB	aldose 1-epimerase
BI313_15095	ENOG4105K5B	UPF0225 protein
BI313_15100	ENOG4105EJ9	Membrane
BI313_15120	ENOG4105EUJ	GTP cyclohydrolase i
BI313_15130	ENOG4105ZQC	membrane protein AaeX
BI313_15135	ENOG4105Y49	secretion protein, HlyD family
BI313_15145	ENOG4105DR8	Membrane
BI313_15150	ENOG4105CSH	Transporter
BI313_15160	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
BI313_15230	ENOG4105CMM	transposase
BI313_15255	ENOG4105VDM	plasmid maintenance system antidote protein, xre family
BI313_15260	ENOG41080ET	plasmid maintenance system killer protein
BI313_15265	ENOG4107QYX	exodeoxyribonuclease v alpha
BI313_15270	ENOG4107QKA	exodeoxyribonuclease V beta
BI313_15275	ENOG4105DSY	exodeoxyribonuclease V, gamma
BI313_15315	ENOG4105DHJ	ABC, transporter
BI313_15320	ENOG4105CY3	ABC transporter, permease
BI313_15325	ENOG4107PE3	Mammalian cell entry related domain protein
BI313_15340	ENOG410903C	(LipO)protein
BI313_15350	ENOG4108V06	Glutathione peroxidase
BI313_15360	ENOG4107QSV	RmuC domain protein
BI313_15365	ENOG4105CIS	alcohol dehydrogenase
BI313_15370	ENOG4105EJC	lysr family transcriptional regulator
BI313_15380	ENOG4108TGY	Glutathione S-transferase
BI313_15390	ENOG4105CUB	amino acid
BI313_15395	ENOG4105CWX	Alpha-1,2-mannosidase
BI313_15400	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
BI313_15405	ENOG4105NRM	Membrane
BI313_15410	ENOG4105BZU	Histidine kinase
BI313_15415	ENOG4105BZW	Glycerate kinase
BI313_15435	ENOG4105DR4	Methyltransferase
BI313_15445	ENOG4105DU1	integral membrane protein, terc
BI313_15460	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
BI313_15485	ENOG4108ZJ4	polysaccharide deacetylase
BI313_15495	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
BI313_15515	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
BI313_15520	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
BI313_15525	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
BI313_15530	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
BI313_15540	ENOG4108K0D	peptidase, M48
BI313_15585	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
BI313_15595	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
BI313_15610	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
BI313_15625	ENOG4108JQ1	Dehydrogenase
BI313_15630	ENOG4105CN1	protease
BI313_15640	ENOG41063SB	peptidase
BI313_15650	ENOG4107VAM	peptidase, m28
BI313_15675	ENOG4105DQ4	alcohol dehydrogenase
BI313_15685	ENOG4105BZ8	glutamate synthase
BI313_15690	ENOG4105CBC	glutamate synthase
BI313_15725	ENOG4105CC0	LysR family Transcriptional regulator
BI313_15800	ENOG4108I5C	dEAD DEAH box helicase
BI313_15805	ENOG4108UT2	hemolysin iii
BI313_15815	ENOG4105CYM	Glutathione S-transferase
BI313_15825	ENOG4105C9K	Endothelin-converting enzyme 1
BI313_15830	ENOG4105CC0	LysR family Transcriptional regulator
BI313_15835	ENOG4105CHR	reductase
BI313_15855	ENOG4105DYS	nad(p)h dehydrogenase (quinone)
BI313_15865	ENOG4105KVH	Transcriptional regulator
BI313_15900	ENOG41067RQ	csbd family
BI313_15945	ENOG4108IND	Tetr family transcriptional regulator
BI313_15965	ENOG4105C02	permease
BI313_15980	ENOG4105K63	Thioredoxin
BI313_15985	ENOG4105CSH	Transporter
BI313_16030	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
BI313_16065	ENOG4105CIR	epoxide hydrolase
BI313_16075	ENOG4108IG5	Transcriptional regulator
BI313_16080	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
BI313_16085	ENOG4105CGF	Aromatic amino acid aminotransferase
BI313_16090	ENOG4105CHB	tonB-dependent Receptor
BI313_16105	ENOG4105C26	Dehydrogenase
BI313_16135	ENOG4105DQE	DNA ligase
BI313_16140	ENOG4105DMF	Dehydrogenase
BI313_16160	ENOG4105BZU	Histidine kinase
BI313_16165	ENOG4105WH1	Two component transcriptional regulator luxr family
BI313_16175	ENOG4108M3R	transcriptional activator CadC
BI313_16180	ENOG4105RKW	reductase (By
BI313_16190	ENOG4105D7K	pfkb domain protein
BI313_16315	ENOG4105EP6	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity)
BI313_16320	ENOG4105CG3	alpha amylase, catalytic region
BI313_16360	ENOG4107TDE	lipolytic protein G-D-S-L family
BI313_16365	ENOG4105EBR	Carboxylesterase
BI313_16380	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
BI313_16390	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
BI313_16395	ENOG4105DSG	hydrolase family 43
BI313_16400	ENOG4105ETE	Transcriptional regulator (LacI family
BI313_16410	ENOG4105D50	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate (By similarity)
BI313_16415	ENOG4105CHR	reductase
BI313_16430	ENOG4107TDE	lipolytic protein G-D-S-L family
BI313_16440	ENOG4105MIR	Phenylalanine 4-monooxygenase
BI313_16445	ENOG4108YXU	transcriptional regulator AsnC family
BI313_16450	ENOG4105CNM	Receptor
BI313_16460	ENOG4105D78	K07001 NTE family protein
BI313_16470	ENOG4105DKW	ABC transporter
BI313_16485	ENOG4108IJ8	ABC transporter
BI313_16490	ENOG4105E90	ABC transporter
BI313_16505	ENOG41067HS	methyltransferase
BI313_16530	ENOG4105D1F	ATP-binding protein
BI313_16535	ENOG4105M4E	phosphohistidine phosphatase, SixA
BI313_16540	ENOG4108YYC	ycei family
BI313_16545	ENOG4107RZC	phospholipase d
BI313_16555	ENOG4105KA0	thioesterase Superfamily protein
BI313_16575	ENOG4108V1U	phospholipid-binding protein
BI313_16585	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
BI313_16595	ENOG4105C5F	glutamine synthetase
BI313_16605	ENOG4105BZU	Histidine kinase
BI313_16610	ENOG4105CUX	Signal transduction histidine kinase
BI313_16615	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
BI313_16620	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
BI313_16625	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
BI313_16645	ENOG4105CHU	acetyl-coa acetyltransferase
BI313_16685	ENOG4107YZP	Rhodanese domain protein
BI313_16690	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
BI313_16695	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
BI313_16705	ENOG4105C7K	acetolactate synthase
BI313_16710	ENOG4108TQ9	Histidine kinase
BI313_16715	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
BI313_16735	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
BI313_16750	ENOG4105E2T	synthase III
BI313_16755	ENOG4107R3N	Filamentation induced by cAMP protein fic
BI313_16760	ENOG4108J2P	Alpha beta hydrolase fold
BI313_16765	ENOG4105PI0	Ferredoxin
BI313_16770	ENOG410680H	amp-dependent synthetase and ligase
BI313_16775	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
BI313_16790	ENOG4105CPF	Cell wall formation (By similarity)
BI313_16800	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
BI313_16810	ENOG4105DR9	pseudouridine synthase
BI313_16820	ENOG4108YZN	class I peptide chain release factor
BI313_16840	ENOG4105DGW	oligopeptidase A
BI313_16845	ENOG4105DGW	oligopeptidase A
BI313_16880	ENOG4105DUM	transcriptional regulator, lysR family
BI313_16885	ENOG4107QP3	malate synthase g
BI313_16925	ENOG4107QX3	carboxylase
BI313_16930	ENOG4105C1G	acyl-Coa dehydrogenase
BI313_16990	ENOG4105CKI	cobalamin synthesis protein
BI313_17005	ENOG4108TZV	Membrane
BI313_17015	ENOG4105D6Z	AFG1 family ATPase
BI313_17020	ENOG4105K56	Transcriptional regulator
BI313_17025	ENOG4108ZHJ	Organic hydroperoxide resistance protein
BI313_17055	ENOG4105CV8	reductase
BI313_17060	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
BI313_17075	ENOG4108R99	pseudouridine synthase
BI313_17085	ENOG4105CQ7	ATP-dependent helicase
BI313_17090	ENOG4105C8Q	Methyl-accepting chemotaxis
BI313_17095	ENOG4108W15	Protein of unknown function (DUF1456)
BI313_17100	ENOG4105VT2	5-hydroxyisourate hydrolase
BI313_17105	ENOG4105E1J	oxidoreductase
BI313_17125	ENOG4105C5R	Aminotransferase
BI313_17135	ENOG4105EQ2	LysR family Transcriptional regulator
BI313_17140	ENOG4107RTG	Major Facilitator superfamily
BI313_17155	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
BI313_17165	ENOG4105DU0	nucleoside hydrolase
BI313_17175	ENOG4105C7N	Xanthine uracil vitamin C permease
BI313_17190	ENOG4108KB2	LysR family Transcriptional regulator
BI313_17195	ENOG4105F8V	Hydrolase, tatD family
BI313_17210	ENOG4106NZI	LysR family Transcriptional regulator
BI313_17215	ENOG4105D94	Major Facilitator Superfamily
BI313_17240	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
BI313_17245	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
BI313_17285	ENOG4105DZ2	Transcriptional regulator
BI313_17290	ENOG4108UZX	fmn reductase
BI313_17300	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
BI313_17305	ENOG4105CAX	The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity)
BI313_17320	ENOG4105E1F	short-chain dehydrogenase reductase
BI313_17325	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
BI313_17430	ENOG4105C01	Dihydroxy-acid dehydratase
BI313_17435	ENOG4105KRS	Proteinase inhibitor
BI313_17440	ENOG4108Z0R	Transferase
BI313_17445	ENOG4105D2S	major facilitator superfamily
BI313_17450	ENOG4105CPI	Metal Dependent Phosphohydrolase
BI313_17480	ENOG4108KB1	transcriptional regulator, arac family
BI313_17495	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
BI313_17500	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
BI313_17505	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
BI313_17510	ENOG4105E98	transcriptional regulator DeoR family
BI313_17540	ENOG4105CHU	acetyl-coa acetyltransferase
BI313_17555	ENOG4107RAW	3-carboxy-cis-cis-muconate cycloisomerase
BI313_17560	ENOG4105F2Z	3-oxoadipate enol-lactonase
BI313_17565	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
BI313_17575	ENOG4107HP6	Transcriptional regulator
BI313_17590	ENOG4105MH3	Protein of unknown function (DUF2490)
BI313_17595	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
BI313_17605	ENOG4105C7B	Threonine dehydratase
BI313_17650	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
BI313_17655	ENOG41081UC	Inherit from COG: Competence protein
BI313_17660	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
BI313_17680	ENOG4105C8Q	Methyl-accepting chemotaxis
BI313_17695	ENOG4105EGS	Mechanosensitive ion channel
BI313_17700	ENOG4107RES	phosphoglycerol transferase I
BI313_17715	ENOG4105CKW	Inner membrane protein yedI
BI313_17720	ENOG4105BZU	Histidine kinase
BI313_17725	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
BI313_17735	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
BI313_17760	ENOG4105K4T	epimerase
BI313_17800	ENOG4105BZS	acriflavin resistance protein
BI313_17805	ENOG4105CHR	reductase
BI313_17810	ENOG4107GJV	short-chain dehydrogenase reductase
BI313_17815	ENOG4105KVH	Transcriptional regulator
BI313_17825	ENOG4105C1J	atp-dependent rna helicase
BI313_17840	ENOG4105C7S	Dehydrogenase
BI313_17850	ENOG4105CPP	Dehydrogenase, E1 component
BI313_17855	ENOG4107RUY	(E1 component), alpha subunit
BI313_17865	ENOG4105HJ8	Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity)
BI313_17870	ENOG4105DUX	Transporter
BI313_17885	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
BI313_17890	ENOG4105WDY	DNA (cytosine-5-)-methyltransferase
BI313_17895	ENOG4105F1J	Homogentisate 1,2-dioxygenase
BI313_17910	ENOG4105KJM	monovalent cation h antiporter subunit g
BI313_17915	ENOG4105W4C	monovalent cation H antiporter subunit F
BI313_17925	ENOG4107R4Z	monovalent cation h antiporter subunit d
BI313_17930	ENOG4108ZE9	Monovalent cation H antiporter subunit C
BI313_17935	ENOG4105D65	subunit l
BI313_17975	ENOG4105C8V	SAICAR synthetase
BI313_17980	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
BI313_18000	ENOG4105KD7	acetyltransferase
BI313_18005	ENOG4107TE5	Lipid kinase
BI313_18010	ENOG4105CRQ	synthase (Component I)
BI313_18025	ENOG4105DZR	Type I site-specific deoxyribonuclease
BI313_18050	ENOG4105DDQ	anthranilate synthase
BI313_18065	ENOG4108I0Q	anthranilate phosphoribosyltransferase
BI313_18070	ENOG4105DK0	Indole-3-glycerol phosphate synthase
BI313_18080	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
BI313_18085	ENOG4105FDS	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
BI313_18095	ENOG4108S0N	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol (By similarity)
BI313_18100	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
BI313_18130	ENOG4108UQY	Iron-storage protein
BI313_18135	ENOG4105BZU	Histidine kinase
BI313_18140	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
BI313_18160	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
BI313_18165	ENOG4105E09	nadh pyrophosphatase
BI313_18170	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
BI313_18200	ENOG4105EM2	membrane
BI313_18205	ENOG4105C12	Phosphoribosylglycinamide synthetase
BI313_18215	ENOG4105DC1	bifunctional purine biosynthesis protein purh
BI313_18220	ENOG4108UMZ	Cdp-alcohol phosphatidyltransferase
BI313_18225	ENOG4105E8V	Alpha Beta Hydrolase Fold protein
BI313_18230	ENOG41077RS	Phosphatase
BI313_18255	ENOG4108HPI	phosphatidate Cytidylyltransferase
BI313_18265	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
BI313_18285	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
BI313_18300	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
BI313_18310	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
BI313_18315	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
BI313_18320	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
BI313_18325	ENOG4105VF7	tolerance protein
BI313_18330	ENOG4108K8S	endonuclease I
BI313_18335	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
BI313_18360	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
BI313_18390	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
BI313_18405	ENOG4105ENX	hydrolase
BI313_18435	ENOG4108RDT	NADH dehydrogenase NAD(P)H nitroreductase)
BI313_18440	ENOG4108YYC	ycei family
BI313_18460	ENOG4105WSE	Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism (By similarity)
BI313_18475	ENOG41065ZS	Transfers 2'-(5-triphosphoribosyl)-3'-dephosphocoenzyme- A to the apo- acyl-carrier-protein of the malonate decarboxylase to yield holo- acyl-carrier-protein (By similarity)
BI313_18480	ENOG4108K6F	triphosphoribosyl-dephospho-CoA synthase
BI313_18495	ENOG4105DRR	Transcriptional regulator, GntR family
BI313_18540	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
BI313_18625	ENOG4105CHF	Glutathione S-transferase
BI313_18670	ENOG4105EYF	MMPL domain protein
BI313_18685	ENOG4107QS8	(LipO)protein
BI313_18690	ENOG4105BZU	Histidine kinase
BI313_18695	ENOG4108Z40	Transcriptional regulator
BI313_18700	ENOG4108JU3	Alkyl hydroperoxide reductase
BI313_18725	ENOG4105DFI	Membrane
BI313_18750	ENOG4105D7N	magnesium and cobalt transport protein CorA
BI313_18805	ENOG4105C8Q	Methyl-accepting chemotaxis
BI313_18810	ENOG4106R7G	Glycoside hydrolase family 5
BI313_18815	ENOG4105CHH	sulfate transporter
BI313_18820	ENOG4105BZU	Histidine kinase
BI313_18850	ENOG4105C3A	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity)
BI313_18860	ENOG4108HRK	Histidine kinase
BI313_18865	ENOG4108NEV	two component transcriptional regulator, LytTR family
BI313_18870	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
BI313_18920	ENOG4105WD1	Membrane
BI313_18930	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
BI313_18940	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
BI313_18950	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
BI313_18955	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
BI313_18970	ENOG4107YB6	acetyltransferase, (GNAT) family
BI313_18985	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
BI313_18990	ENOG4105BZU	Histidine kinase
BI313_18995	ENOG4105CD8	aminopeptidase N
BI313_19010	ENOG4105DZG	Dehydrogenase
BI313_19015	ENOG4108Q1J	Extracellular solute-binding protein, family 3
BI313_19040	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
BI313_19050	ENOG4105DFF	Rod shape-determining protein mreb
BI313_19055	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
BI313_19070	ENOG4105CNI	cell division protein FtsW
BI313_19080	ENOG4105CVE	Lytic murein transglycosylase
BI313_19085	ENOG4105K6T	rare lipoprotein A
BI313_19090	ENOG4105DZ1	carboxypeptidase
BI313_19110	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
BI313_19115	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
BI313_19120	ENOG4105CN1	protease
BI313_19130	ENOG4105F04	LysR family Transcriptional regulator
BI313_19175	ENOG4108J5G	6-phosphogluconate dehydrogenase
BI313_19180	ENOG4105D9R	oxidoreductase
BI313_19185	ENOG4105W4M	Transport-associated protein
BI313_19190	ENOG4105BZU	Histidine kinase
BI313_19200	ENOG4105BZU	Histidine kinase
BI313_19210	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
BI313_19250	ENOG4105GVR	general secretion pathway protein D
BI313_19255	ENOG4107QHF	type ii secretion system protein e
BI313_19260	ENOG4105D7Q	type ii secretion system
BI313_19265	ENOG4108VAU	general secretion pathway protein G
BI313_19270	ENOG4105VWV	general secretion pathway protein h
BI313_19275	ENOG4105X5Z	General secretion pathway protein I
BI313_19285	ENOG4105R04	type II secretion system protein K
BI313_19305	ENOG4105FDP	GntR family transcriptional regulator
BI313_19315	ENOG4105ETE	Transcriptional regulator (LacI family
BI313_19320	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
BI313_19325	ENOG4105CE4	GlcNAc 6-P deacetylase
BI313_19345	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
BI313_19360	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
BI313_19375	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
BI313_19385	ENOG4108K5H	permease YjgP YjgQ family protein
BI313_19400	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
BI313_19405	ENOG4105T95	Thiol disulfide interChange protein
BI313_19410	ENOG4108ETH	Formylglycinamide ribotide synthetase
BI313_19420	ENOG4105EUR	Domain-Containing protein
BI313_19425	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
BI313_19430	ENOG4107QHF	type ii secretion system protein e
BI313_19435	ENOG4105D7Q	type ii secretion system
BI313_19445	ENOG4105WMT	general secretion pathway protein h
BI313_19455	ENOG41069G9	General secretion pathway protein J
BI313_19460	ENOG4105UV2	general secretion pathway protein K
BI313_19465	ENOG41090VX	general secretion pathway protein L
BI313_19470	ENOG410678M	general secretion pathway protein M
BI313_19480	ENOG4105GVR	general secretion pathway protein D
BI313_19500	ENOG4108K85	Transcriptional regulator
BI313_19545	ENOG4107RH7	Nicotinate phosphoribosyltransferase
BI313_19560	ENOG4107QZ7	Cellulose synthase catalytic subunit
BI313_19565	ENOG4107EEX	Cellulose synthase regulator protein
BI313_19570	ENOG4105K2Z	endo-1,4-d-glucanase (EC 3.2.1.4)
BI313_19575	ENOG4105EJG	cellulose synthase
BI313_19595	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
BI313_19600	ENOG4105C5H	ABC transporter
BI313_19610	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
BI313_19615	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
BI313_19625	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
BI313_19640	ENOG4108R6K	riboflavin synthase, subunit alpha
BI313_19645	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
BI313_19650	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
BI313_19660	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
BI313_19685	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
BI313_19690	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
BI313_19700	ENOG4105C08	Histidine kinase
BI313_19705	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
BI313_19710	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
BI313_19715	ENOG4105CQB	FAD linked oxidase domain protein
BI313_19720	ENOG4105S2T	inner membrane protein YbcI
BI313_19770	ENOG4106932	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
BI313_19775	ENOG4105CJN	penicillin-binding protein
BI313_19780	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
BI313_19785	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
BI313_19790	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
BI313_19800	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
BI313_19805	ENOG4105DFU	Cell wall formation (By similarity)
BI313_19810	ENOG4105CPF	Cell wall formation (By similarity)
BI313_19815	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
BI313_19820	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
BI313_19825	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
BI313_19830	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
BI313_19840	ENOG4105DR5	peptidase
BI313_19860	ENOG4105M6F	mutator MutT protein
BI313_19875	ENOG4105SYT	Methylenetetrahydrofolate reductase
BI313_19945	ENOG4105DXX	methyltransferase
BI313_19950	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
BI313_19960	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
BI313_19980	ENOG4105F37	PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6
BI313_20000	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
BI313_20010	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
BI313_20020	ENOG4108RVA	ribokinase
BI313_20025	ENOG4105D9N	nucleoside
BI313_20030	ENOG4105CPC	Aldo Keto reductase
BI313_20040	ENOG4105D05	Receptor
BI313_20085	ENOG4108I0Y	(ABC) transporter
BI313_20090	ENOG4108UJV	acyl-CoA thioesterase i
BI313_20095	ENOG4105ETX	regulatoR
BI313_20100	ENOG4105DHQ	Histidine kinase
BI313_20110	ENOG41080IJ	Diacylglycerol kinase
BI313_20120	ENOG4105HA9	of methanol dehydrogenase type
BI313_20130	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
BI313_20150	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
BI313_20155	ENOG4105NWN	ApaG protein
BI313_20160	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
BI313_20165	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
BI313_20175	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
BI313_20185	ENOG4108WBT	adenosyltransferase
BI313_20195	ENOG4105D0A	hydroxylase
BI313_20200	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
BI313_20235	ENOG4105DDW	LysR family Transcriptional regulator
BI313_20240	ENOG4105CEY	Amp-dependent synthetase and ligase
BI313_20250	ENOG4108D7R	p-hydroxycinnamoyl CoA hydratase lyase
BI313_20280	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
BI313_20300	ENOG4105DXC	membrane
BI313_20305	ENOG4105CX6	glutaminyL-tRNA synthetase
BI313_20320	ENOG4105BZU	Histidine kinase
BI313_20325	ENOG4105BZU	Histidine kinase
BI313_20330	ENOG4105WH1	Two component transcriptional regulator luxr family
BI313_20340	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
BI313_20350	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
BI313_20355	ENOG4105NXH	GreA GreB family elongation factor
BI313_20360	ENOG4105C5Q	Transcriptional regulator
BI313_20375	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
BI313_20395	ENOG4105C2M	dna polymerase I
BI313_20400	ENOG41069NU	Nitroreductase
BI313_20430	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
BI313_20450	ENOG4105W8H	transhydrogenase (subunit alpha
BI313_20455	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
BI313_20475	ENOG4105CM2	brancheD-chain amino acid aminotransferase
BI313_20485	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
BI313_20490	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
BI313_20495	ENOG4108Z66	YbaK ebsC protein
BI313_20510	ENOG4105CS1	NAD(P)H quinone oxidoreductase
BI313_20515	ENOG4107S2Z	UPF0761 membrane protein
BI313_20520	ENOG4107QX9	Thiol disulfide interChange protein
BI313_20535	ENOG4105CSR	polyphosphate kinase 2
BI313_20540	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
BI313_20560	ENOG4105DJQ	tetratricopeptide tpr_2 repeat protein
BI313_20565	ENOG4105QVB	outer membrane lipoprotein LolB
BI313_20570	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
BI313_20580	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
BI313_20585	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
BI313_20590	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
BI313_20595	ENOG4105C3G	gtp-binding protein
BI313_20600	ENOG4105DFP	Integrase
BI313_20655	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
BI313_20665	ENOG4105PM1	preprotein translocase subunit SecE
BI313_20670	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
BI313_20675	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
BI313_20680	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
BI313_20685	ENOG4108VZM	50s ribosomal protein L10
BI313_20690	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
BI313_20700	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
BI313_20705	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
BI313_20710	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
BI313_20715	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
BI313_20720	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
BI313_20725	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
BI313_20730	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
BI313_20735	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
BI313_20740	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
BI313_20745	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BI313_20750	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
BI313_20765	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
BI313_20775	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
BI313_20780	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
BI313_20785	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
BI313_20790	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BI313_20795	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
BI313_20800	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
BI313_20805	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
BI313_20810	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
BI313_20815	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
BI313_20825	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
BI313_20830	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
BI313_20835	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BI313_20840	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
BI313_20845	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
BI313_20850	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
BI313_20855	ENOG4108ZT0	50S ribosomal protein l17
BI313_20860	ENOG41080I0	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
BI313_20870	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
BI313_20880	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
BI313_20895	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
BI313_20900	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
BI313_20905	ENOG4108K3A	Glutathione S-transferase
BI313_20920	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
BI313_20935	ENOG4105F37	PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6
BI313_20945	ENOG4108R99	pseudouridine synthase
BI313_20955	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
BI313_20960	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
BI313_20965	ENOG4108I5D	sulfate abc transporter
BI313_20975	ENOG4108IJ6	ABC transporter
BI313_20985	ENOG4105CPQ	Dehydrogenase
BI313_20995	ENOG4105HSS	phospholipase C
BI313_21005	ENOG4105CVJ	phosphoglycerate mutase
BI313_21015	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
BI313_21030	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
BI313_21035	ENOG4105ED9	Protein of unknown function (DUF455)
BI313_21040	ENOG4108YP4	Metalloprotease, specifically cleaves on the N-terminal side of aspartyl, glutamyl and cysteic acid residues (By similarity)
BI313_21050	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
BI313_21055	ENOG4105EYK	Phosphatidylglycerophosphatase B
BI313_21060	ENOG4105BZF	Glycosyl transferase (Group 1
BI313_21065	ENOG4105C9X	ppx gppa phosphatase
BI313_21070	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
BI313_21075	ENOG4105BZU	Histidine kinase
BI313_21080	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
BI313_21085	ENOG4105ERG	peptidase m48, ste24p
BI313_21090	ENOG4105VW4	glutaredoxin 3
BI313_21100	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
BI313_21135	ENOG4105BZU	Histidine kinase
BI313_21145	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
BI313_21150	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
BI313_21155	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
BI313_21185	ENOG4105EIN	peptidylprolyl cis-trans isomerase
BI313_21195	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
BI313_21205	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
BI313_21210	ENOG4108JDX	DNA polymerase iii, epsilon subunit
BI313_21215	ENOG4108ZF3	Phosphatase
BI313_21230	ENOG4105DKP	glycosyl transferase, family 9
BI313_21235	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
BI313_21240	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
BI313_21245	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
BI313_21250	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
BI313_21255	ENOG4105M00	molybdopterin converting factor, subunit 1
BI313_21260	ENOG4108ZAF	Molybdopterin
BI313_21275	ENOG4107QMP	dna polymerase iii subunits gamma and tau
BI313_21280	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
BI313_21290	ENOG4105K59	histidine triad (HIT) protein
BI313_21300	ENOG4105F8C	transglutaminase domain-containing protein
BI313_21310	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
BI313_21320	ENOG41089I4	Inherit from COG: Glycosyl transferase, family 2
BI313_21330	ENOG4108UHJ	MAF-like protein
BI313_21335	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
BI313_21340	ENOG4105VGS	50s ribosomal protein l32
BI313_21345	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
BI313_21350	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
BI313_21355	ENOG4105CHR	reductase
BI313_21360	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
BI313_21365	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
BI313_21375	ENOG4105HHA	aminodeoxychorismate lyase
BI313_21380	ENOG4107QRG	dna polymerase iii
BI313_21400	ENOG4108JU7	Transcriptional regulator
BI313_21405	ENOG4105CR4	methylisocitrate lyase
BI313_21410	ENOG4105BZN	citrate synthase
BI313_21415	ENOG4108I0Z	Aconitate hydratase
BI313_21425	ENOG4105C7F	AcnD-accessory protein PrpF
BI313_21445	ENOG4105DN3	alpha-2-macroglobulin domain protein
BI313_21470	ENOG4108JQB	penicillin-binding protein 1C
BI313_21495	ENOG4105M3Z	response regulator
BI313_21500	ENOG4107QJR	hflk protein
BI313_21505	ENOG4105EPW	hflc protein
BI313_21510	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
BI313_21585	ENOG4105DZR	Type I site-specific deoxyribonuclease
BI313_21615	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
BI313_21620	ENOG4105CVJ	phosphoglycerate mutase
BI313_21625	ENOG4107Z4K	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
BI313_21635	ENOG4105BZP	glycoside hydrolase 15-related
BI313_21640	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
BI313_21650	ENOG4105CWX	Alpha-1,2-mannosidase
BI313_21705	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
BI313_21710	ENOG4105DQ4	alcohol dehydrogenase
BI313_21720	ENOG4105C7W	Xanthine dehydrogenase
BI313_21725	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
BI313_21730	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
BI313_21755	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
BI313_21775	ENOG4105C0B	DNA polymerase III (alpha subunit)
BI313_21790	ENOG4105EPD	Oligopeptide transporter, Opt family
BI313_21800	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
BI313_21815	ENOG4106AXJ	AraC family transcriptional regulator
BI313_21830	ENOG4105CV8	reductase
BI313_21835	ENOG4105EBR	Carboxylesterase
BI313_21840	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BI313_21845	ENOG4105C2C	drug resistance transporter, Bcr CflA
BI313_21865	ENOG4105DIJ	Phosphoethanolamine transferase
BI313_21880	ENOG4105ETX	regulatoR
BI313_21885	ENOG4105US7	Histidine kinase
BI313_21895	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
BI313_21900	ENOG4107QMS	site-determining protein
BI313_21905	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
BI313_21915	ENOG4105BZU	Histidine kinase
BI313_21920	ENOG4105WH1	Two component transcriptional regulator luxr family
BI313_21985	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
BI313_22005	ENOG4105C29	acyl-CoA thioesterase
BI313_22010	ENOG4105E39	Enoyl-CoA hydratase
BI313_22015	ENOG4108TGP	Thioesterase superfamily protein
BI313_22020	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
BI313_22025	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
BI313_22035	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BI313_22040	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
BI313_22045	ENOG4105CJR	Integral membrane protein (MviN
BI313_22050	ENOG4105DTN	riboflavin biosynthesis protein ribF
BI313_22060	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
BI313_22065	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
BI313_22075	ENOG4105E2S	oxidase) subunit II
BI313_22080	ENOG4105BZ9	Cytochrome C oxidase, subunit I
BI313_22085	ENOG4105CCU	oxidase (Subunit III)
BI313_22090	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
BI313_22100	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
BI313_22105	ENOG4105KAF	membrAne
BI313_22120	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
BI313_22130	ENOG4107MMM	Anti-sigma-factor antagonist
BI313_22135	ENOG4105FUA	antagonist
BI313_22140	ENOG4105QD0	anti-sigma regulatory factor serine threonine protein kinase
BI313_22150	ENOG4105BZU	Histidine kinase
BI313_22180	ENOG4105KCV	RNA signal recognition particle 4.5S RNA
BI313_22185	ENOG4105BZU	Histidine kinase
BI313_22190	ENOG4107Z5C	methylesterase
BI313_22195	ENOG4105BZU	Histidine kinase
BI313_22200	ENOG4105BZU	Histidine kinase
BI313_22205	ENOG4105BZU	Histidine kinase
BI313_22230	ENOG4105CZZ	Alpha-N-arabinofuranosidase (EC 3.2.1.55)
BI313_22235	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
BI313_22240	ENOG4105CRE	cytochrome C
BI313_22245	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BI313_22255	ENOG4105EA8	2-Nitropropane dioxygenase
BI313_22265	ENOG4105K5M	30s ribosomal protein S16
BI313_22270	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
BI313_22275	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
BI313_22285	ENOG4107QJQ	Mate efflux family protein
BI313_22290	ENOG4105VEJ	Heat shock protein
BI313_22295	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
BI313_22305	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
BI313_22310	ENOG4105C8Q	Methyl-accepting chemotaxis
BI313_22330	ENOG4105CNT	hydrolase family 2
BI313_22335	ENOG4106FKC	arabinogalactan endo-1,4-beta-galactosidase
BI313_22350	ENOG4105C26	Dehydrogenase
BI313_22355	ENOG4105C1G	acyl-Coa dehydrogenase
BI313_22360	ENOG4105E39	Enoyl-CoA hydratase
BI313_22365	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
BI313_22370	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
BI313_22390	ENOG4105EMN	RNA polymerase sigma factor
BI313_22400	ENOG4105C0H	protease
BI313_22405	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
BI313_22410	ENOG4105C3F	Signal peptidase i
BI313_22420	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
BI313_22425	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
BI313_22445	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
BI313_22455	ENOG41080ZE	Adenylate cyclase
BI313_22460	ENOG4107ZXU	DSBA oxidoreductase
BI313_22465	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
BI313_22470	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
BI313_22475	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
BI313_22480	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
BI313_22485	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
BI313_22490	ENOG4105VEQ	Cold shock protein
BI313_22495	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
BI313_22505	ENOG4107QRT	dEAD DEAH box helicase
BI313_22510	ENOG4107T0X	DNA ligase
BI313_22520	ENOG4107T0X	DNA ligase
BI313_22535	ENOG4105BZU	Histidine kinase
BI313_22550	ENOG4105CHU	acetyl-coa acetyltransferase
BI313_22570	ENOG4108VKG	metal-dependent hydrolase
BI313_22585	ENOG4105KSC	Transcriptional regulator, TraR DksA family
BI313_22620	ENOG4105DFF	Rod shape-determining protein mreb
BI313_22625	ENOG4108YZY	peptidylprolyl cis-trans isomerase
BI313_22635	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
BI313_22650	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
BI313_22655	ENOG4105F27	Major Facilitator
BI313_22700	ENOG4105M4H	endoribonuclease L-psp
BI313_22705	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
BI313_22720	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
BI313_22745	ENOG4105K6V	RNA polymerase
BI313_22760	ENOG4108R3D	Electron transport complex
BI313_22770	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
BI313_22790	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
BI313_22795	ENOG4108IQI	permease
BI313_22800	ENOG4107QK5	Homocysteine s-methyltransferase
BI313_22860	ENOG4108YXA	Membrane
BI313_22870	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
BI313_22880	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
BI313_22885	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
BI313_22890	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
BI313_22895	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
BI313_22900	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
BI313_22915	ENOG4105DZP	Membrane-associated zinc metalloprotease
BI313_22920	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
BI313_22925	ENOG4105KNE	Phosphatidate cytidylyltransferase
BI313_22930	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
BI313_22935	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
BI313_22940	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
BI313_22945	ENOG4105BZU	Histidine kinase
BI313_22950	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
BI313_22955	ENOG4105CE9	30S ribosomal protein S2
BI313_22990	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
BI313_22995	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
BI313_23010	ENOG4105KUZ	arsenate reductase
BI313_23015	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
BI313_23020	ENOG4105CAQ	asparagine synthetase
BI313_23030	ENOG4108ESX	Receptor
BI313_23040	ENOG4108UWD	Iron-storage protein
BI313_23045	ENOG4105FQ6	thiopurine methyltransferase
BI313_23055	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
BI313_23075	ENOG4105CW7	secretion protein, HlyD family
BI313_23080	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
BI313_23105	ENOG4105DUX	Transporter
BI313_23135	ENOG4105DGW	oligopeptidase A
BI313_23145	ENOG4105DP0	ferredoxin-NADP reductase
BI313_23165	ENOG4107GFK	fumarate
BI313_23185	ENOG4105HDD	phospholipase
BI313_23195	ENOG4105VEQ	Cold shock protein
BI313_23210	ENOG4105CUZ	uba thif-type nad fad binding protein
BI313_23215	ENOG4105F8V	Hydrolase, tatD family
BI313_23230	ENOG4105C1G	acyl-Coa dehydrogenase
BI313_23240	ENOG4108K3A	Glutathione S-transferase
BI313_23245	ENOG4105CAQ	asparagine synthetase
BI313_23255	ENOG4105CDU	Replicative dna helicase
BI313_23260	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
BI313_23270	ENOG4105CDV	Ompa motb domain protein
BI313_23275	ENOG4105CR8	Transcriptional regulator
BI313_23290	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
BI313_23310	ENOG4105BZU	Histidine kinase
BI313_23450	ENOG4108VSE	mercuric transport protein
BI313_23465	ENOG4105D13	transposase
BI313_23480	ENOG4108R0M	Aminoglycoside
BI313_23495	ENOG4108C33	Resolvase
BI313_23640	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
BI313_23670	ENOG4105EVZ	LysR family transcriptional regulator