locus-tag	class	description
XBW1_0002	COG0592	DNA-directed DNA polymerase activity
XBW1_0003	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
XBW1_0004	COG0187	DNA topoisomerase II activity
XBW1_0012	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
XBW1_0014	COG1943	Transposase
XBW1_0021	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
XBW1_0023	COG0355	proton-transporting ATP synthase activity, rotational mechanism
XBW1_0024	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
XBW1_0025	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
XBW1_0026	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
XBW1_0027	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
XBW1_0028	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
XBW1_0030	COG0356	it plays a direct role in the translocation of protons across the membrane
XBW1_0031	COG3312	ion transport
XBW1_0032	COG0357	Ribosomal RNA small subunit methyltransferase G
XBW1_0033	COG0445	tRNA wobble uridine modification
XBW1_0035	COG0716	FMN binding
XBW1_0036	COG1522	sequence-specific DNA binding
XBW1_0037	COG2502	aspartate--ammonia ligase
XBW1_0038	COG2425	protein containing a von Willebrand factor type A (vWA) domain
XBW1_0039	COG0714	Associated with various cellular activities
XBW1_0040	COG1869	D-ribose catabolic process
XBW1_0041	COG1129	ABC transporter
XBW1_0042	COG1172	Belongs to the binding-protein-dependent transport system permease family
XBW1_0043	COG1879	ABC-type sugar transport system periplasmic component
XBW1_0044	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XBW1_0045	COG1609	Transcriptional regulator
XBW1_0046	COG0477	Major facilitator Superfamily
XBW1_0050	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
XBW1_0051	COG3162	membrane
XBW1_0052	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
XBW1_0053	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
XBW1_0054	COG0180	Tryptophanyl-tRNA synthetase
XBW1_0055	COG0546	phosphoglycolate phosphatase activity
XBW1_0056	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
XBW1_0059	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
XBW1_0060	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
XBW1_0061	COG4796	Type ii and iii secretion system protein
XBW1_0066	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
XBW1_0069	COG0494	nUDIX hydrolase
XBW1_0072	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
XBW1_0073	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
XBW1_0074	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
XBW1_0075	COG1741	Belongs to the pirin family
XBW1_0077	COG1454	alcohol dehydrogenase
XBW1_0086	COG5433	transposase activity
XBW1_0096	COG1012	belongs to the aldehyde dehydrogenase family
XBW1_0100	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
XBW1_0101	COG3152	Membrane
XBW1_0102	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XBW1_0105	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
XBW1_0106	COG5433	transposase activity
XBW1_0109	COG2192	nodulation
XBW1_0116	COG2081	HI0933 family
XBW1_0117	COG0306	phosphate transporter
XBW1_0118	COG1943	Transposase
XBW1_0120	COG0589	response to stress
XBW1_0122	COG0742	ribosomal rna small subunit methyltransferase
XBW1_0126	COG0366	Alpha amylase catalytic
XBW1_0127	COG1263	PTS System
XBW1_0127	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
XBW1_0134	COG1671	Belongs to the UPF0178 family
XBW1_0137	COG3964	amidohydrolase
XBW1_0143	COG2213	PTS system mannitol-specific
XBW1_0143	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
XBW1_0150	COG1794	racemase activity, acting on amino acids and derivatives
XBW1_0151	COG1181	Belongs to the D-alanine--D-alanine ligase family
XBW1_0153	COG3327	negative regulation of DNA-templated transcription, initiation
XBW1_0154	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
XBW1_0155	COG0183	Belongs to the thiolase family
XBW1_0156	COG2050	protein possibly involved in aromatic compounds catabolism
XBW1_0157	COG1250	3-hydroxyacyl-CoA dehydrogenase
XBW1_0158	COG1024	Enoyl-CoA hydratase
XBW1_0159	COG1024	Enoyl-CoA hydratase
XBW1_0160	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
XBW1_0161	COG2151	metal-sulfur cluster biosynthetic enzyme
XBW1_0162	COG3396	Phenylacetate-CoA oxygenase
XBW1_0163	COG3460	Phenylacetate-CoA oxygenase
XBW1_0164	COG3396	Phenylacetate-CoA oxygenase
XBW1_0165	COG1012	belongs to the aldehyde dehydrogenase family
XBW1_0165	COG2030	dehydratase
XBW1_0170	COG3335	DDE superfamily endonuclease
XBW1_0174	COG0626	cystathionine gamma-synthase activity
XBW1_0177	COG1735	metal-dependent hydrolase with the TIM-barrel fold
XBW1_0178	COG3457	Alanine racemase
XBW1_0180	COG2188	Transcriptional regulator
XBW1_0182	COG3293	Transposase
XBW1_0197	COG0582	viral genome integration into host DNA
XBW1_0222	COG3501	Rhs element vgr protein
XBW1_0242	COG3335	DDE superfamily endonuclease
XBW1_0244	COG1295	ribonuclease BN
XBW1_0245	COG1942	4-Oxalocrotonate Tautomerase
XBW1_0247	COG2814	Major facilitator Superfamily
XBW1_0250	COG0612	Peptidase, M16
XBW1_0251	COG2199	diguanylate cyclase activity
XBW1_0251	COG2200	EAL domain
XBW1_0252	COG4608	Belongs to the ABC transporter superfamily
XBW1_0253	COG0444	Belongs to the ABC transporter superfamily
XBW1_0254	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
XBW1_0255	COG0601	transmembrane transport
XBW1_0256	COG0747	negative chemotaxis
XBW1_0258	COG0751	glycine-tRNA ligase activity
XBW1_0259	COG0752	glycyl-tRNA synthetase alpha subunit
XBW1_0260	COG2818	Glycosylase
XBW1_0261	COG3977	Valine--pyruvate aminotransferase
XBW1_0263	COG0823	Involved in the tonB-independent uptake of proteins
XBW1_0264	COG2860	membrane
XBW1_0265	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
XBW1_0266	COG0194	GDP metabolic process
XBW1_0268	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
XBW1_0270	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
XBW1_0271	COG0786	glutamate:sodium symporter activity
XBW1_0273	COG2233	PERMEase
XBW1_0274	COG2982	Protein involved in outer membrane biogenesis
XBW1_0275	COG0456	acetyltransferase
XBW1_0276	COG1490	D-aminoacyl-tRNA deacylase activity
XBW1_0277	COG1011	Hydrolase
XBW1_0295	COG0635	Involved in the biosynthesis of porphyrin-containing compound
XBW1_0299	COG2252	PERMEase
XBW1_0309	COG3157	Type VI secretion system effector, Hcp
XBW1_0310	COG0765	amino acid transport
XBW1_0311	COG0765	amino acid transport
XBW1_0312	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
XBW1_0313	COG1943	Transposase
XBW1_0314	COG0704	Plays a role in the regulation of phosphate uptake
XBW1_0315	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
XBW1_0316	COG0581	inorganic phosphate transmembrane transporter activity
XBW1_0317	COG0573	inorganic phosphate transmembrane transporter activity
XBW1_0318	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
XBW1_0320	COG0745	RESPONSE REGULATOR receiver
XBW1_0321	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XBW1_0322	COG2183	response to ionizing radiation
XBW1_0324	COG1918	ferrous iron import across plasma membrane
XBW1_0328	COG3077	Addiction module antitoxin, RelB DinJ family
XBW1_0330	COG0596	Alpha beta hydrolase
XBW1_0331	COG1040	competence protein
XBW1_0332	COG0316	Belongs to the HesB IscA family
XBW1_0332	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
XBW1_0333	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
XBW1_0334	COG0705	Rhomboid family
XBW1_0335	COG1349	DNA-binding transcription factor activity
XBW1_0337	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
XBW1_0340	COG2188	Transcriptional regulator
XBW1_0341	COG3293	Transposase
XBW1_0344	COG1802	Transcriptional regulator
XBW1_0344	COG4626	Terminase
XBW1_0345	COG3423	Transcriptional regulator
XBW1_0348	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
XBW1_0349	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XBW1_0353	COG1070	Carbohydrate kinase
XBW1_0354	COG2390	Transcriptional regulator
XBW1_0358	COG1879	ABC-type sugar transport system periplasmic component
XBW1_0359	COG1830	Aldolase
XBW1_0360	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
XBW1_0365	COG1763	Mo-molybdopterin cofactor biosynthetic process
XBW1_0366	COG0746	molybdenum cofactor guanylyltransferase activity
XBW1_0367	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
XBW1_0369	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
XBW1_0369	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
XBW1_0370	COG0218	Necessary for normal cell division and for the maintenance of normal septation
XBW1_0371	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
XBW1_0375	COG3954	Phosphoribulokinase
XBW1_0376	COG3089	Belongs to the UPF0270 family
XBW1_0378	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
XBW1_0378	COG1263	PTS System
XBW1_0379	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
XBW1_0380	COG3677	Transposase
XBW1_0381	COG1662	PFAM IS1 transposase
XBW1_0383	COG3547	Transposase (IS116 IS110 IS902 family)
XBW1_0384	COG0583	DNA-binding transcription factor activity
XBW1_0386	COG0488	(ABC) transporter
XBW1_0387	COG2249	NAD(P)H dehydrogenase (quinone) activity
XBW1_0389	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
XBW1_0391	COG1047	Peptidyl-prolyl cis-trans
XBW1_0392	COG2900	Belongs to the SlyX family
XBW1_0393	COG0545	Peptidyl-prolyl cis-trans isomerase
XBW1_0394	COG2964	Protein conserved in bacteria
XBW1_0395	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
XBW1_0396	COG2923	Belongs to the DsrF TusC family
XBW1_0397	COG2168	tRNA wobble position uridine thiolation
XBW1_0398	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
XBW1_0399	COG0049	tRNA binding
XBW1_0400	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
XBW1_0403	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
XBW1_0404	COG0250	Participates in transcription elongation, termination and antitermination
XBW1_0405	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
XBW1_0406	COG0081	regulation of translation
XBW1_0407	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
XBW1_0408	COG0222	ribosome binding
XBW1_0409	COG0085	RNA polymerase activity
XBW1_0410	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
XBW1_0411	COG0726	polysaccharide deacetylase
XBW1_0414	COG4580	involved in the transport of maltose and maltodextrins
XBW1_0415	COG3842	ATPase activity
XBW1_0417	COG1175	transmembrane transport
XBW1_0418	COG3833	ABC-type maltose transport systems, permease component
XBW1_0419	COG1640	4-alpha-glucanotransferase
XBW1_0420	COG0058	SHG alpha-glucan phosphorylase activity
XBW1_0421	COG2909	trisaccharide binding
XBW1_0422	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
XBW1_0423	COG1064	alcohol dehydrogenase
XBW1_0424	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
XBW1_0425	COG2223	nitrite transmembrane transporter activity
XBW1_0428	COG2022	thiamine diphosphate biosynthetic process
XBW1_0429	COG2104	thiamine diphosphate biosynthetic process
XBW1_0430	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
XBW1_0431	COG0352	thiamine-phosphate diphosphorylase activity
XBW1_0432	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
XBW1_0435	COG2816	NAD+ diphosphatase activity
XBW1_0436	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
XBW1_0437	COG1515	deoxyribonuclease V activity
XBW1_0438	COG3068	Protein conserved in bacteria
XBW1_0439	COG0776	regulation of translation
XBW1_0441	COG0151	Belongs to the GarS family
XBW1_0442	COG0138	bifunctional purine biosynthesis protein purh
XBW1_0447	COG1914	H( )-stimulated, divalent metal cation uptake system
XBW1_0448	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
XBW1_0449	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
XBW1_0450	COG4770	biotin carboxylase activity
XBW1_0453	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
XBW1_0455	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
XBW1_0456	COG1053	succinate dehydrogenase
XBW1_0457	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
XBW1_0458	COG0584	glycerophosphoryl diester phosphodiesterase
XBW1_0459	COG2271	Major facilitator Superfamily
XBW1_0465	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
XBW1_0466	COG0425	Belongs to the sulfur carrier protein TusA family
XBW1_0468	COG3776	membrane
XBW1_0469	COG0742	ribosomal rna small subunit methyltransferase
XBW1_0471	COG0552	protein localization to endoplasmic reticulum
XBW1_0471	COG0552	protein localization to endoplasmic reticulum
XBW1_0472	COG2884	Cell division ATP-binding protein ftsE
XBW1_0473	COG2177	Part of the ABC transporter FtsEX involved in
XBW1_0475	COG1929	Belongs to the glycerate kinase type-1 family
XBW1_0476	COG0456	acetyltransferase
XBW1_0480	COG3501	Rhs element vgr protein
XBW1_0487	COG0683	leucine binding
XBW1_0488	COG0559	Belongs to the binding-protein-dependent transport system permease family
XBW1_0490	COG0411	ABC transporter
XBW1_0491	COG0410	ABC transporter
XBW1_0498	COG3335	DDE superfamily endonuclease
XBW1_0504	COG2814	Major facilitator Superfamily
XBW1_0524	COG3423	Transcriptional regulator
XBW1_0526	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
XBW1_0527	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
XBW1_0528	COG2264	protein methyltransferase activity
XBW1_0529	COG4145	pantothenate transmembrane transporter activity
XBW1_0530	COG3924	membrane
XBW1_0532	COG0439	Biotin carboxylase
XBW1_0533	COG0511	ligase activity, forming carbon-carbon bonds
XBW1_0534	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
XBW1_0535	COG0604	alcohol dehydrogenase
XBW1_0536	COG1077	Cell shape determining protein MreB Mrl
XBW1_0537	COG1792	Involved in formation and maintenance of cell shape
XBW1_0538	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
XBW1_0539	COG0424	maF-like protein
XBW1_0540	COG1530	ribonuclease E activity
XBW1_0541	COG3164	Protein of unknown function
XBW1_0542	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XBW1_0543	COG0312	modulator of DNA gyrase
XBW1_0545	COG2732	(Barnase) inhibitor
XBW1_0552	COG3028	Belongs to the UPF0307 family
XBW1_0553	COG0312	modulator of DNA gyrase
XBW1_0554	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XBW1_0557	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
XBW1_0558	COG1660	Displays ATPase and GTPase activities
XBW1_0559	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
XBW1_0561	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
XBW1_0562	COG1137	ATPase activity
XBW1_0563	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
XBW1_0564	COG3117	lipopolysaccharide transmembrane transporter activity
XBW1_0565	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
XBW1_0566	COG0517	IMP dehydrogenase activity
XBW1_0566	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
XBW1_0567	COG0530	calcium, potassium:sodium antiporter activity
XBW1_0568	COG1127	ABC transporter
XBW1_0569	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
XBW1_0570	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
XBW1_0571	COG2854	intermembrane phospholipid transfer
XBW1_0573	COG5007	Belongs to the BolA IbaG family
XBW1_0574	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
XBW1_0575	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XBW1_0577	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XBW1_0578	COG3105	Protein conserved in bacteria
XBW1_0580	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
XBW1_0581	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
XBW1_0582	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
XBW1_0583	COG0625	glutathione transferase activity
XBW1_0584	COG2969	positive regulation of protein catabolic process
XBW1_0586	COG0493	'glutamate synthase
XBW1_0587	COG0067	glutamate synthase
XBW1_0587	COG0070	glutamate synthase
XBW1_0587	COG0069	glutamate synthase activity
XBW1_0588	COG0784	Response regulator, receiver
XBW1_0588	COG2198	Histidine kinase
XBW1_0588	COG5002	protein histidine kinase activity
XBW1_0589	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
XBW1_0590	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
XBW1_0591	COG2823	Periplasmic or secreted lipoprotein
XBW1_0592	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
XBW1_0593	COG0792	nuclease activity
XBW1_0595	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
XBW1_0596	COG1741	Belongs to the pirin family
XBW1_0597	COG0583	DNA-binding transcription factor activity
XBW1_0598	COG2259	Doxx family
XBW1_0600	COG3335	DDE superfamily endonuclease
XBW1_0607	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
XBW1_0608	COG4575	ribosome binding
XBW1_0609	COG0586	Pfam SNARE associated Golgi protein
XBW1_0610	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
XBW1_0611	COG0446	pyridine nucleotide-disulphide oxidoreductase
XBW1_0611	COG1902	pentaerythritol trinitrate reductase activity
XBW1_0613	COG2990	Protein conserved in bacteria
XBW1_0615	COG0477	Major facilitator Superfamily
XBW1_0616	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
XBW1_0617	COG1028	Short-chain dehydrogenase reductase Sdr
XBW1_0619	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
XBW1_0624	COG1216	Glycosyl transferase, family 2
XBW1_0625	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
XBW1_0628	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
XBW1_0629	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
XBW1_0640	COG2345	Transcriptional regulator
XBW1_0656	COG3423	Transcriptional regulator
XBW1_0658	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
XBW1_0659	COG0358	DNA primase activity
XBW1_0661	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
XBW1_0663	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
XBW1_0664	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
XBW1_0665	COG0617	tRNA 3'-terminal CCA addition
XBW1_0666	COG4991	sh3 domain protein
XBW1_0667	COG3025	triphosphatase activity
XBW1_0668	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
XBW1_0669	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
XBW1_0669	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
XBW1_0671	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
XBW1_0672	COG3384	dioxygenase
XBW1_0673	COG0754	glutathionylspermidine amidase activity
XBW1_0674	COG5463	Belongs to the UPF0441 family
XBW1_0675	COG1538	Outer membrane efflux protein
XBW1_0676	COG0494	nUDIX hydrolase
XBW1_0677	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
XBW1_0678	COG3150	esterase
XBW1_0679	COG0187	DNA topoisomerase II activity
XBW1_0680	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
XBW1_0681	COG0204	Acyl-transferase
XBW1_0682	COG2132	Multicopper oxidase
XBW1_0684	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
XBW1_0685	COG2967	ApaG domain
XBW1_0686	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
XBW1_0687	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
XBW1_0688	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
XBW1_0689	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
XBW1_0690	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
XBW1_0691	COG0564	pseudouridine synthase activity
XBW1_0692	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
XBW1_0693	COG0417	DNA replication proofreading
XBW1_0703	COG3335	DDE superfamily endonuclease
XBW1_0704	COG1028	Short-chain dehydrogenase reductase Sdr
XBW1_0706	COG3033	Beta-eliminating lyase
XBW1_0710	COG0582	viral genome integration into host DNA
XBW1_0719	COG1358	cellular component organization or biogenesis
XBW1_0723	COG2862	Uncharacterized protein family, UPF0114
XBW1_0726	COG1250	3-hydroxyacyl-CoA dehydrogenase
XBW1_0728	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
XBW1_0729	COG1960	acyl-CoA dehydrogenase activity
XBW1_0733	COG3293	Transposase
XBW1_0744	COG3335	DDE superfamily endonuclease
XBW1_0745	COG3335	DDE superfamily endonuclease
XBW1_0751	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
XBW1_0771	COG4695	Portal protein
XBW1_0773	COG4626	Terminase
XBW1_0773	COG1802	Transcriptional regulator
XBW1_0783	COG3293	Transposase
XBW1_0787	COG0305	Participates in initiation and elongation during chromosome replication
XBW1_0788	COG1484	DNA-dependent DNA replication
XBW1_0796	COG5301	cellulose 1,4-beta-cellobiosidase activity
XBW1_0804	COG3041	Addiction module toxin RelE StbE family
XBW1_0805	COG3077	Addiction module antitoxin, RelB DinJ family
XBW1_0825	COG2369	cell adhesion
XBW1_0826	COG3567	Phage-associated protein, HI1409 family
XBW1_0847	COG1484	DNA-dependent DNA replication
XBW1_0864	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
XBW1_0875	COG0582	viral genome integration into host DNA
XBW1_0876	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
XBW1_0877	COG2501	S4 domain
XBW1_0879	COG0215	cysteine-tRNA ligase activity
XBW1_0880	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
XBW1_0881	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XBW1_0882	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
XBW1_0883	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
XBW1_0884	COG0307	riboflavin synthase, alpha
XBW1_0887	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XBW1_0888	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
XBW1_0889	COG4181	ATPase activity
XBW1_0890	COG2755	lipolytic protein G-D-S-L family
XBW1_0891	COG0300	oxidoreductase activity
XBW1_0892	COG3118	belongs to the thioredoxin family
XBW1_0893	COG0330	HflC and HflK could
XBW1_0895	COG0789	Transcriptional regulator
XBW1_0896	COG2217	Heavy metal translocating P-type atpase
XBW1_0897	COG3735	TraB family
XBW1_0898	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
XBW1_0901	COG0737	Belongs to the 5'-nucleotidase family
XBW1_0902	COG2223	nitrite transmembrane transporter activity
XBW1_0903	COG4651	solute:proton antiporter activity
XBW1_0903	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
XBW1_0904	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XBW1_0905	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
XBW1_0906	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
XBW1_0907	COG0563	adenylate kinase activity
XBW1_0908	COG0326	Molecular chaperone. Has ATPase activity
XBW1_0911	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
XBW1_0912	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
XBW1_0913	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
XBW1_0914	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
XBW1_0917	COG1196	nuclear chromosome segregation
XBW1_0917	COG3264	Mechanosensitive ion channel
XBW1_0918	COG1309	transcriptional regulator
XBW1_0919	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XBW1_0920	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XBW1_0926	COG1946	Acyl-CoA thioesterase
XBW1_0927	COG0004	ammonium transporteR
XBW1_0928	COG0347	Belongs to the P(II) protein family
XBW1_0930	COG1132	(ABC) transporter
XBW1_0931	COG1132	(ABC) transporter
XBW1_0932	COG1522	sequence-specific DNA binding
XBW1_0934	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
XBW1_0935	COG0824	Thioesterase
XBW1_0936	COG1555	photosystem II stabilization
XBW1_0937	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
XBW1_0939	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
XBW1_0940	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
XBW1_0941	COG0740	serine-type endopeptidase activity
XBW1_0942	COG0544	peptidyl-prolyl cis-trans isomerase activity
XBW1_0944	COG0271	Belongs to the BolA IbaG family
XBW1_0945	COG3056	Lipoprotein
XBW1_0946	COG2223	nitrite transmembrane transporter activity
XBW1_0949	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
XBW1_0950	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
XBW1_0951	COG1845	cytochrome c oxidase, subunit III
XBW1_0952	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
XBW1_0953	COG0109	protoheme IX farnesyltransferase activity
XBW1_0954	COG2814	Major facilitator Superfamily
XBW1_0956	COG1666	GTP binding
XBW1_0957	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
XBW1_0958	COG0693	protein deglycase activity
XBW1_0959	COG0301	tRNA thio-modification
XBW1_0959	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
XBW1_0961	COG0142	geranyltranstransferase activity
XBW1_0962	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
XBW1_0970	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
XBW1_0971	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
XBW1_0972	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
XBW1_0973	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
XBW1_0974	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
XBW1_0975	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
XBW1_0975	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
XBW1_0976	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
XBW1_0977	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
XBW1_0979	COG1862	Preprotein translocase
XBW1_0981	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
XBW1_0982	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
XBW1_0984	COG0450	alkyl hydroperoxide reductase
XBW1_0986	COG1114	Component of the transport system for branched-chain amino acids
XBW1_0988	COG5002	protein histidine kinase activity
XBW1_0989	COG0745	RESPONSE REGULATOR receiver
XBW1_0990	COG0420	3'-5' exonuclease activity
XBW1_0991	COG0419	ATPase involved in DNA repair
XBW1_1000	COG0737	Belongs to the 5'-nucleotidase family
XBW1_1001	COG1940	carbohydrate kinase activity
XBW1_1003	COG2974	May be involved in recombination
XBW1_1004	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
XBW1_1007	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
XBW1_1008	COG3525	Glycosyl hydrolase, family 20, catalytic domain
XBW1_1027	COG1802	Transcriptional regulator
XBW1_1027	COG4626	Terminase
XBW1_1031	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
XBW1_1035	COG0848	biopolymer transport protein
XBW1_1036	COG0811	peptide transport
XBW1_1038	COG0626	cystathionine gamma-synthase activity
XBW1_1039	COG0586	Pfam SNARE associated Golgi protein
XBW1_1040	COG0656	L-ascorbic acid biosynthetic process
XBW1_1042	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
XBW1_1043	COG0505	Belongs to the CarA family
XBW1_1044	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
XBW1_1059	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
XBW1_1060	COG1047	Peptidyl-prolyl cis-trans
XBW1_1061	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
XBW1_1062	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
XBW1_1063	COG0196	riboflavin kinase activity
XBW1_1065	COG0268	Binds directly to 16S ribosomal RNA
XBW1_1066	COG0583	DNA-binding transcription factor activity
XBW1_1067	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
XBW1_1070	COG0484	heat shock protein binding
XBW1_1071	COG0443	Heat shock 70 kDa protein
XBW1_1072	COG1584	GPR1 FUN34 yaaH family protein
XBW1_1073	COG0477	Major facilitator Superfamily
XBW1_1081	COG1960	acyl-CoA dehydrogenase activity
XBW1_1093	COG0521	Mo-molybdopterin cofactor biosynthetic process
XBW1_1094	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
XBW1_1095	COG3022	response to hydroperoxide
XBW1_1097	COG0083	homoserine kinase activity
XBW1_1099	COG0745	RESPONSE REGULATOR receiver
XBW1_1100	COG3045	CreA protein
XBW1_1102	COG2207	Transcriptional regulator
XBW1_1102	COG3708	Transcriptional regulator
XBW1_1103	COG0406	alpha-ribazole phosphatase activity
XBW1_1104	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
XBW1_1105	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
XBW1_1106	COG0741	lytic transglycosylase activity
XBW1_1107	COG0488	(ABC) transporter
XBW1_1108	COG1136	(ABC) transporter
XBW1_1108	COG0577	efflux transmembrane transporter activity
XBW1_1110	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
XBW1_1111	COG0560	Phosphoserine phosphatase
XBW1_1112	COG3726	membrane protein affecting hemolysin expression
XBW1_1118	COG3121	Chaperone
XBW1_1119	COG3188	usher protein
XBW1_1120	COG3539	Fimbrial protein
XBW1_1121	COG0813	purine-nucleoside phosphorylase activity
XBW1_1122	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
XBW1_1123	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
XBW1_1124	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
XBW1_1125	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
XBW1_1126	COG0084	hydrolase, TatD family'
XBW1_1127	COG4667	esterase of the alpha-beta hydrolase superfamily
XBW1_1130	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
XBW1_1131	COG0456	acetyltransferase
XBW1_1132	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
XBW1_1133	COG2813	Specifically methylates the guanine in position
XBW1_1135	COG1012	belongs to the aldehyde dehydrogenase family
XBW1_1137	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XBW1_1140	COG3423	Transcriptional regulator
XBW1_1141	COG2076	Multidrug Resistance protein
XBW1_1142	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
XBW1_1143	COG1509	lysine 2,3-aminomutase activity
XBW1_1145	COG0459	protein refolding
XBW1_1146	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
XBW1_1148	COG1027	Aspartate ammonia-lyase
XBW1_1149	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
XBW1_1150	COG4232	protein-disulfide reductase activity
XBW1_1152	COG1309	transcriptional regulator
XBW1_1153	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
XBW1_1163	COG3547	Transposase (IS116 IS110 IS902 family)
XBW1_1166	COG3293	Transposase
XBW1_1178	COG3501	Rhs element vgr protein
XBW1_1180	COG3209	COG3209 Rhs family protein
XBW1_1204	COG3423	Transcriptional regulator
XBW1_1206	COG3335	DDE superfamily endonuclease
XBW1_1215	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
XBW1_1221	COG0305	Participates in initiation and elongation during chromosome replication
XBW1_1224	COG0582	viral genome integration into host DNA
XBW1_1232	COG3501	Rhs element vgr protein
XBW1_1235	COG3423	Transcriptional regulator
XBW1_1247	COG1943	Transposase
XBW1_1252	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
XBW1_1265	COG3501	Rhs element vgr protein
XBW1_1272	COG1662	PFAM IS1 transposase
XBW1_1274	COG3335	DDE superfamily endonuclease
XBW1_1297	COG3423	Transcriptional regulator
XBW1_1304	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
XBW1_1330	COG0464	growth
XBW1_1335	COG3293	Transposase
XBW1_1342	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
XBW1_1344	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
XBW1_1351	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
XBW1_1370	COG2249	NAD(P)H dehydrogenase (quinone) activity
XBW1_1379	COG3423	Transcriptional regulator
XBW1_1380	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
XBW1_1386	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
XBW1_1400	COG3335	DDE superfamily endonuclease
XBW1_1406	COG3335	DDE superfamily endonuclease
XBW1_1409	COG5301	cellulose 1,4-beta-cellobiosidase activity
XBW1_1410	COG2304	oxidoreductase activity
XBW1_1418	COG1136	(ABC) transporter
XBW1_1420	COG1262	PFAM Formylglycine-generating sulfatase enzyme
XBW1_1429	COG0741	lytic transglycosylase activity
XBW1_1429	COG1388	LysM domain
XBW1_1430	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XBW1_1431	COG2226	methyltransferase
XBW1_1436	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
XBW1_1439	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
XBW1_1440	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
XBW1_1450	COG3335	DDE superfamily endonuclease
XBW1_1452	COG2368	4-hydroxyphenylacetate
XBW1_1453	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
XBW1_1454	COG3104	oligopeptide transport
XBW1_1455	COG2271	Major facilitator Superfamily
XBW1_1457	COG2197	response regulator
XBW1_1462	COG3501	Rhs element vgr protein
XBW1_1473	COG3971	2-oxopent-4-enoate hydratase activity
XBW1_1476	COG3384	dioxygenase
XBW1_1477	COG1012	belongs to the aldehyde dehydrogenase family
XBW1_1479	COG0179	Fumarylacetoacetate (FAA) hydrolase
XBW1_1480	COG1846	Transcriptional regulator
XBW1_1483	COG2226	methyltransferase
XBW1_1483	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
XBW1_1483	COG3433	isochorismatase activity
XBW1_1484	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
XBW1_1484	COG2226	methyltransferase
XBW1_1484	COG3433	isochorismatase activity
XBW1_1490	COG1132	(ABC) transporter
XBW1_1492	COG3316	Transposase and inactivated derivatives
XBW1_1495	COG4592	Periplasmic binding protein
XBW1_1497	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
XBW1_1498	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
XBW1_1499	COG1120	ATPase activity
XBW1_1501	COG3251	PFAM MbtH domain protein
XBW1_1502	COG2382	esterase
XBW1_1503	COG4774	siderophore transport
XBW1_1504	COG1169	isochorismate synthase
XBW1_1505	COG1021	2,3-dihydroxybenzoate-AMP ligase
XBW1_1506	COG3433	isochorismatase activity
XBW1_1506	COG1535	isochorismatase
XBW1_1507	COG1028	Short-chain dehydrogenase reductase Sdr
XBW1_1508	COG2814	Major facilitator Superfamily
XBW1_1511	COG2814	Major facilitator Superfamily
XBW1_1515	COG3962	Belongs to the TPP enzyme family
XBW1_1516	COG0673	inositol 2-dehydrogenase activity
XBW1_1517	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
XBW1_1518	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XBW1_1520	COG3718	enzyme involved in inositol metabolism
XBW1_1525	COG1309	transcriptional regulator
XBW1_1548	COG1943	Transposase
XBW1_1552	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
XBW1_1556	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XBW1_1557	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
XBW1_1557	COG1648	precorrin-2 dehydrogenase activity
XBW1_1559	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
XBW1_1561	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
XBW1_1562	COG2241	protein methyltransferase activity
XBW1_1564	COG2875	Belongs to the precorrin methyltransferase family
XBW1_1574	COG1492	cobalamin metabolic process
XBW1_1575	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
XBW1_1578	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
XBW1_1579	COG0318	PFAM AMP-dependent synthetase and ligase
XBW1_1580	COG1028	Short-chain dehydrogenase reductase Sdr
XBW1_1581	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
XBW1_1592	COG3772	lysozyme
XBW1_1598	COG5301	cellulose 1,4-beta-cellobiosidase activity
XBW1_1605	COG1216	Glycosyl transferase, family 2
XBW1_1606	COG0463	Glycosyl transferase, family 2
XBW1_1617	COG2841	Protein conserved in bacteria
XBW1_1619	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
XBW1_1620	COG0740	serine-type endopeptidase activity
XBW1_1626	COG3038	cytochrome b561
XBW1_1628	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
XBW1_1631	COG0372	Belongs to the citrate synthase family
XBW1_1637	COG3293	Transposase
XBW1_1641	COG5433	transposase activity
XBW1_1642	COG0582	viral genome integration into host DNA
XBW1_1644	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
XBW1_1645	COG2867	negative regulation of translational initiation
XBW1_1646	COG2914	Belongs to the UPF0125 (RnfH) family
XBW1_1647	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XBW1_1648	COG0497	DNA recombination
XBW1_1649	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
XBW1_1650	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
XBW1_1651	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
XBW1_1653	COG0513	Belongs to the DEAD box helicase family
XBW1_1664	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
XBW1_1665	COG0736	holo-[acyl-carrier-protein] synthase activity
XBW1_1666	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
XBW1_1667	COG1381	Involved in DNA repair and RecF pathway recombination
XBW1_1668	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
XBW1_1669	COG0571	ribonuclease III activity
XBW1_1670	COG0681	Belongs to the peptidase S26 family
XBW1_1671	COG0481	GTPase activity
XBW1_1672	COG3086	response to oxidative stress
XBW1_1675	COG1595	DNA-templated transcription, initiation
XBW1_1676	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
XBW1_1685	COG1943	Transposase
XBW1_1729	COG0484	heat shock protein binding
XBW1_1753	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
XBW1_1756	COG1418	mRNA catabolic process
XBW1_1757	COG0590	tRNA wobble adenosine to inosine editing
XBW1_1758	COG1943	Transposase
XBW1_1759	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
XBW1_1760	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
XBW1_1760	COG0047	phosphoribosylformylglycinamidine synthase activity
XBW1_1761	COG2205	protein histidine kinase activity
XBW1_1762	COG3170	Tfp pilus assembly protein FimV
XBW1_1763	COG2204	response regulator
XBW1_1764	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
XBW1_1764	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XBW1_1765	COG0347	Belongs to the P(II) protein family
XBW1_1766	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
XBW1_1766	COG1017	nitric oxide dioxygenase activity
XBW1_1771	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
XBW1_1772	COG2814	Major facilitator Superfamily
XBW1_1774	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
XBW1_1775	COG1959	2 iron, 2 sulfur cluster binding
XBW1_1776	COG1104	cysteine desulfurase activity
XBW1_1777	COG0822	iron-sulfur transferase activity
XBW1_1778	COG0316	Belongs to the HesB IscA family
XBW1_1779	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
XBW1_1780	COG0443	Heat shock 70 kDa protein
XBW1_1781	COG0633	Ferredoxin
XBW1_1782	COG2975	iron-sulfur cluster assembly
XBW1_1783	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
XBW1_1785	COG2373	Large extracellular alpha-helical protein
XBW1_1786	COG4953	penicillin-binding protein 1C
XBW1_1788	COG3655	Transcriptional regulator
XBW1_1790	COG0105	UTP biosynthetic process
XBW1_1791	COG0820	rRNA (adenine-C2-)-methyltransferase activity
XBW1_1794	COG1426	Protein conserved in bacteria
XBW1_1795	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
XBW1_1796	COG0124	histidyl-tRNA synthetase
XBW1_1797	COG2976	Protein conserved in bacteria
XBW1_1798	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XBW1_1799	COG1160	GTP binding
XBW1_1801	COG1943	Transposase
XBW1_1803	COG0408	coproporphyrinogen oxidase activity
XBW1_1804	COG0456	acetyltransferase
XBW1_1808	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
XBW1_1809	COG4208	sulfate ABC transporter
XBW1_1810	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
XBW1_1812	COG2190	(PTS) system
XBW1_1814	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
XBW1_1816	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
XBW1_1818	COG3115	cell septum assembly
XBW1_1819	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
XBW1_1820	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
XBW1_1821	COG3530	Putative quorum-sensing-regulated virulence factor
XBW1_1822	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
XBW1_1828	COG0859	PFAM glycosyl transferase family 9
XBW1_1832	COG0582	viral genome integration into host DNA
XBW1_1833	COG0582	viral genome integration into host DNA
XBW1_1838	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
XBW1_1858	COG0183	Belongs to the thiolase family
XBW1_1859	COG1024	Enoyl-CoA hydratase
XBW1_1859	COG1250	3-hydroxyacyl-CoA dehydrogenase
XBW1_1860	COG2062	phosphohistidine phosphatase, SixA
XBW1_1862	COG0582	viral genome integration into host DNA
XBW1_1875	COG5433	transposase activity
XBW1_1876	COG0484	heat shock protein binding
XBW1_1882	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
XBW1_1887	COG0579	oxidoreductase
XBW1_1890	COG5433	transposase activity
XBW1_1899	COG2249	NAD(P)H dehydrogenase (quinone) activity
XBW1_1900	COG2207	Transcriptional regulator
XBW1_1902	COG0012	GTP binding
XBW1_1903	COG0193	aminoacyl-tRNA hydrolase activity
XBW1_1907	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
XBW1_1908	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
XBW1_1909	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
XBW1_1910	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
XBW1_1911	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
XBW1_1912	COG2890	protein-(glutamine-N5) methyltransferase activity
XBW1_1913	COG2912	Transglutaminase-like superfamily
XBW1_1914	COG2877	3-deoxy-8-phosphooctulonate synthase activity
XBW1_1915	COG0659	secondary active sulfate transmembrane transporter activity
XBW1_1917	COG0671	phosphoesterase, PA-phosphatase related
XBW1_1917	COG2453	phosphatase
XBW1_1918	COG2267	carboxylic ester hydrolase activity
XBW1_1919	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
XBW1_1920	COG2378	regulation of single-species biofilm formation
XBW1_1923	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
XBW1_1924	COG3381	protein complex oligomerization
XBW1_1926	COG0477	Major facilitator Superfamily
XBW1_1927	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
XBW1_1929	COG1943	Transposase
XBW1_1931	COG0018	arginyl-trna synthetase
XBW1_1933	COG3102	Protein conserved in bacteria
XBW1_1934	COG3142	Participates in the control of copper homeostasis
XBW1_1936	COG0500	methyltransferase
XBW1_1937	COG2226	methyltransferase
XBW1_1938	COG3788	relative of glutathione S-transferase, MAPEG superfamily
XBW1_1939	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
XBW1_1940	COG0494	nUDIX hydrolase
XBW1_1941	COG0217	transcriptional regulatory protein
XBW1_1942	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
XBW1_1943	COG0632	four-way junction helicase activity
XBW1_1944	COG2255	four-way junction helicase activity
XBW1_1946	COG2184	nucleotidyltransferase activity
XBW1_1947	COG1108	ABC-type Mn2 Zn2 transport systems permease components
XBW1_1948	COG1121	(ABC) transporter
XBW1_1949	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
XBW1_1950	COG0739	heme binding
XBW1_1951	COG1560	Kdo2-lipid A biosynthetic process
XBW1_1952	COG0469	pyruvate kinase activity
XBW1_1953	COG1737	Transcriptional regulator
XBW1_1954	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
XBW1_1955	COG2076	Multidrug Resistance protein
XBW1_1956	COG2076	Multidrug Resistance protein
XBW1_1957	COG0251	oxidation-reduction process
XBW1_1958	COG1199	ATP-dependent helicase activity
XBW1_1960	COG3065	identical protein binding
XBW1_1961	COG0318	PFAM AMP-dependent synthetase and ligase
XBW1_1963	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
XBW1_1968	COG3293	Transposase
XBW1_1970	COG2801	Transposase and inactivated derivatives
XBW1_1999	COG3047	cAMP biosynthetic process
XBW1_2003	COG0159	tryptophan synthase activity
XBW1_2004	COG0133	tryptophan synthase activity
XBW1_2006	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
XBW1_2009	COG3293	Transposase
XBW1_2012	COG3335	DDE superfamily endonuclease
XBW1_2015	COG3293	Transposase
XBW1_2018	COG1943	Transposase
XBW1_2023	COG0009	L-threonylcarbamoyladenylate synthase
XBW1_2025	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
XBW1_2026	COG1028	Short-chain dehydrogenase reductase Sdr
XBW1_2027	COG0616	signal peptide processing
XBW1_2031	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
XBW1_2036	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
XBW1_2037	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
XBW1_2038	COG0284	orotidine-5'-phosphate decarboxylase activity
XBW1_2039	COG0023	Translation Initiation Factor
XBW1_2051	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
XBW1_2052	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
XBW1_2054	COG4659	FMN binding
XBW1_2058	COG4657	Part of a membrane complex involved in electron transport
XBW1_2060	COG0673	inositol 2-dehydrogenase activity
XBW1_2061	COG0385	Bile acid
XBW1_2062	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
XBW1_2063	COG5339	Protein conserved in bacteria
XBW1_2064	COG1482	cell wall glycoprotein biosynthetic process
XBW1_2065	COG0114	fumarate hydratase activity
XBW1_2068	COG2814	Major facilitator Superfamily
XBW1_2069	COG0583	DNA-binding transcription factor activity
XBW1_2070	COG1940	carbohydrate kinase activity
XBW1_2071	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
XBW1_2076	COG4221	oxidoreductase activity
XBW1_2080	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
XBW1_2080	COG0456	acetyltransferase
XBW1_2081	COG2801	Transposase and inactivated derivatives
XBW1_2099	COG2814	Major facilitator Superfamily
XBW1_2101	COG0697	spore germination
XBW1_2109	COG1846	Transcriptional regulator
XBW1_2121	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XBW1_2122	COG0625	glutathione transferase activity
XBW1_2127	COG2271	Major facilitator Superfamily
XBW1_2129	COG2814	Major facilitator Superfamily
XBW1_2133	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XBW1_2134	COG0589	response to stress
XBW1_2135	COG4974	Belongs to the 'phage' integrase family
XBW1_2141	COG3335	DDE superfamily endonuclease
XBW1_2143	COG5433	transposase activity
XBW1_2151	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
XBW1_2152	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
XBW1_2155	COG0531	amino acid
XBW1_2158	COG3121	Chaperone
XBW1_2163	COG1643	Atp-dependent helicase
XBW1_2164	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
XBW1_2165	COG3784	Protein of unknown function (DUF1318)
XBW1_2167	COG5433	transposase activity
XBW1_2168	COG2911	Protein conserved in bacteria
XBW1_2169	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
XBW1_2174	COG3335	DDE superfamily endonuclease
XBW1_2176	COG2983	Belongs to the UPF0260 family
XBW1_2177	COG0179	Fumarylacetoacetate (FAA) hydrolase
XBW1_2178	COG2951	lytic endotransglycosylase activity
XBW1_2179	COG3100	YcgL domain-containing protein
XBW1_2180	COG0850	regulation of cytokinetic process
XBW1_2181	COG2894	cell division
XBW1_2182	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
XBW1_2184	COG5433	transposase activity
XBW1_2190	COG5301	cellulose 1,4-beta-cellobiosidase activity
XBW1_2196	COG3316	Transposase and inactivated derivatives
XBW1_2197	COG3469	chitinase activity
XBW1_2200	COG3316	Transposase and inactivated derivatives
XBW1_2202	COG3064	Membrane
XBW1_2202	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
XBW1_2202	COG1073	alpha beta
XBW1_2209	COG2917	probably involved in intracellular septation
XBW1_2210	COG1607	acyl-coa hydrolase
XBW1_2211	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
XBW1_2216	COG0444	Belongs to the ABC transporter superfamily
XBW1_2217	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
XBW1_2218	COG0601	transmembrane transport
XBW1_2222	COG2095	MarC family integral membrane protein
XBW1_2223	COG1012	belongs to the aldehyde dehydrogenase family
XBW1_2223	COG1454	alcohol dehydrogenase
XBW1_2224	COG1435	thymidine kinase activity
XBW1_2228	COG1210	Utp--glucose-1-phosphate uridylyltransferase
XBW1_2229	COG0745	RESPONSE REGULATOR receiver
XBW1_2230	COG3012	SEC-C Motif Domain Protein
XBW1_2231	COG0788	formyltetrahydrofolate deformylase activity
XBW1_2235	COG0708	Exodeoxyribonuclease III
XBW1_2236	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
XBW1_2237	COG0709	Synthesizes selenophosphate from selenide and ATP
XBW1_2238	COG0778	Nitroreductase
XBW1_2239	COG0616	signal peptide processing
XBW1_2240	COG0252	asparaginase activity
XBW1_2241	COG1335	isochorismatase
XBW1_2242	COG3139	Protein of unknown function (DUF1315)
XBW1_2243	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
XBW1_2246	COG3713	MltA-interacting MipA family protein
XBW1_2247	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
XBW1_2248	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XBW1_2249	COG3293	Transposase
XBW1_2250	COG2186	Transcriptional regulator
XBW1_2251	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
XBW1_2252	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
XBW1_2267	COG3501	Rhs element vgr protein
XBW1_2274	COG3335	DDE superfamily endonuclease
XBW1_2280	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
XBW1_2281	COG1271	oxidase subunit
XBW1_2282	COG1294	oxidase, subunit
XBW1_2284	COG3850	Histidine kinase
XBW1_2285	COG1702	phosphate starvation-inducible protein PhoH
XBW1_2286	COG2356	endonuclease I
XBW1_2287	COG0589	response to stress
XBW1_2288	COG0589	response to stress
XBW1_2289	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
XBW1_2290	COG2313	pseudouridylate synthase activity
XBW1_2291	COG1522	sequence-specific DNA binding
XBW1_2291	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XBW1_2293	COG0531	amino acid
XBW1_2294	COG1982	Orn Lys Arg decarboxylase major
XBW1_2295	COG2169	Transcriptional regulator
XBW1_2295	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
XBW1_2323	COG3335	DDE superfamily endonuclease
XBW1_2328	COG1943	Transposase
XBW1_2344	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
XBW1_2345	COG1988	membrane-bound metal-dependent
XBW1_2347	COG0501	Belongs to the peptidase M48B family
XBW1_2349	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
XBW1_2350	COG1956	GAF domain-containing protein
XBW1_2353	COG1276	copper resistance
XBW1_2354	COG2372	response to copper ion
XBW1_2355	COG1528	Iron-storage protein
XBW1_2359	COG3140	Belongs to the UPF0181 family
XBW1_2361	COG0494	nUDIX hydrolase
XBW1_2362	COG1760	l-serine dehydratase
XBW1_2363	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
XBW1_2363	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
XBW1_2364	COG3715	PTS system
XBW1_2365	COG3716	PTS system mannose fructose sorbose family IID component
XBW1_2366	COG4811	Protein of unknown function (DUF986)
XBW1_2367	COG1971	Probably functions as a manganese efflux pump
XBW1_2368	COG2226	methyltransferase
XBW1_2374	COG0519	Catalyzes the synthesis of GMP from XMP
XBW1_2374	COG0518	GMP synthase (glutamine-hydrolyzing) activity
XBW1_2375	COG0517	IMP dehydrogenase activity
XBW1_2375	COG0516	GMP reductase activity
XBW1_2376	COG1570	exodeoxyribonuclease VII activity
XBW1_2377	COG4206	TonB-dependent receptor
XBW1_2377	COG1629	transport
XBW1_2378	COG1770	oligopeptidase
XBW1_2383	COG2197	response regulator
XBW1_2384	COG1393	Belongs to the ArsC family
XBW1_2385	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XBW1_2386	COG1876	peptidase activity
XBW1_2388	COG1444	tRNA N-acetyltransferase activity
XBW1_2389	COG2707	UPF0756 membrane protein
XBW1_2392	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
XBW1_2393	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
XBW1_2394	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
XBW1_2395	COG2716	regulation of RNA biosynthetic process
XBW1_2396	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
XBW1_2397	COG0628	permease
XBW1_2398	COG4783	chaperone-mediated protein folding
XBW1_2399	COG1393	Belongs to the ArsC family
XBW1_2400	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
XBW1_2401	COG2233	PERMEase
XBW1_2402	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
XBW1_2403	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
XBW1_2404	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
XBW1_2405	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
XBW1_2406	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
XBW1_2407	COG0248	Ppx GppA phosphatase
XBW1_2408	COG2239	Acts as a magnesium transporter
XBW1_2410	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XBW1_2411	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XBW1_2412	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XBW1_2413	COG2205	protein histidine kinase activity
XBW1_2414	COG0745	RESPONSE REGULATOR receiver
XBW1_2417	COG1830	Aldolase
XBW1_2418	COG0351	phosphomethylpyrimidine kinase
XBW1_2421	COG0582	viral genome integration into host DNA
XBW1_2435	COG1943	Transposase
XBW1_2436	COG1278	Cold shock
XBW1_2438	COG1113	amino acid transport
XBW1_2440	COG2207	Transcriptional regulator
XBW1_2441	COG3023	N-Acetylmuramoyl-L-alanine amidase
XBW1_2442	COG1115	amino acid carrier protein
XBW1_2448	COG1690	Belongs to the RtcB family
XBW1_2450	COG3335	DDE superfamily endonuclease
XBW1_2453	COG0814	amino acid
XBW1_2457	COG0538	isocitrate dehydrogenase activity
XBW1_2458	COG1187	pseudouridine synthase activity
XBW1_2460	COG0482	sulfurtransferase activity
XBW1_2461	COG2915	High frequency lysogenization protein hflD homolog
XBW1_2462	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
XBW1_2464	COG0745	RESPONSE REGULATOR receiver
XBW1_2465	COG2205	protein histidine kinase activity
XBW1_2466	COG2850	peptidyl-arginine hydroxylation
XBW1_2468	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
XBW1_2469	COG4591	ABC-type transport system involved in lipoprotein release permease component
XBW1_2470	COG1136	(ABC) transporter
XBW1_2471	COG4591	ABC-type transport system involved in lipoprotein release permease component
XBW1_2473	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
XBW1_2476	COG3335	DDE superfamily endonuclease
XBW1_2477	COG1252	NADH dehydrogenase
XBW1_2478	COG1472	Belongs to the glycosyl hydrolase 3 family
XBW1_2480	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
XBW1_2481	COG0537	adenosine 5'-monophosphoramidase activity
XBW1_2482	COG0084	hydrolase, TatD family'
XBW1_2483	COG0470	DNA polymerase III
XBW1_2484	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
XBW1_2485	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
XBW1_2486	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
XBW1_2487	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
XBW1_2488	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
XBW1_2489	COG1028	Short-chain dehydrogenase reductase Sdr
XBW1_2490	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
XBW1_2491	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XBW1_2492	COG0416	fatty acid biosynthetic process
XBW1_2493	COG0333	Belongs to the bacterial ribosomal protein bL32 family
XBW1_2494	COG1399	metal-binding, possibly nucleic acid-binding protein
XBW1_2495	COG0424	maF-like protein
XBW1_2496	COG0564	pseudouridine synthase activity
XBW1_2497	COG1530	ribonuclease E activity
XBW1_2499	COG1943	Transposase
XBW1_2501	COG2926	Belongs to the UPF0265 family
XBW1_2502	COG2925	Exonuclease
XBW1_2504	COG0277	FAD linked oxidase domain protein
XBW1_2505	COG0531	amino acid
XBW1_2506	COG4771	TonB-dependent receptor
XBW1_2507	COG1120	ATPase activity
XBW1_2508	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
XBW1_2510	COG0833	amino acid
XBW1_2511	COG0583	DNA-binding transcription factor activity
XBW1_2512	COG2855	membrane
XBW1_2513	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
XBW1_2514	COG1105	Belongs to the carbohydrate kinase PfkB family
XBW1_2515	COG0494	nUDIX hydrolase
XBW1_2517	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
XBW1_2520	COG0671	phosphoesterase, PA-phosphatase related
XBW1_2521	COG0791	NLP P60 protein
XBW1_2524	COG2814	Major facilitator Superfamily
XBW1_2525	COG1187	pseudouridine synthase activity
XBW1_2526	COG1061	Type III restriction enzyme res subunit
XBW1_2527	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
XBW1_2528	COG3081	Nucleoid-associated protein
XBW1_2529	COG3082	Protein of unknown function (DUF1414)
XBW1_2530	COG3083	sulfuric ester hydrolase activity
XBW1_2535	COG5433	transposase activity
XBW1_2538	COG3335	DDE superfamily endonuclease
XBW1_2552	COG1250	3-hydroxyacyl-CoA dehydrogenase
XBW1_2558	COG4615	Cyclic peptide transporter
XBW1_2561	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
XBW1_2564	COG1960	acyl-CoA dehydrogenase activity
XBW1_2568	COG0582	viral genome integration into host DNA
XBW1_2569	COG1943	Transposase
XBW1_2570	COG1677	Flagellar hook-basal body complex protein FliE
XBW1_2571	COG1766	The M ring may be actively involved in energy transduction
XBW1_2572	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
XBW1_2574	COG1157	protein secretion by the type III secretion system
XBW1_2575	COG2882	bacterial-type flagellum organization
XBW1_2576	COG3144	bacterial-type flagellum assembly
XBW1_2578	COG1580	Controls the rotational direction of flagella during chemotaxis
XBW1_2583	COG1987	bacterial-type flagellum assembly
XBW1_2585	COG1028	Short-chain dehydrogenase reductase Sdr
XBW1_2590	COG5433	transposase activity
XBW1_2599	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
XBW1_2600	COG1256	bacterial-type flagellum assembly
XBW1_2602	COG1706	bacterial-type flagellum-dependent cell motility
XBW1_2604	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
XBW1_2605	COG4786	Flagellar basal body rod
XBW1_2607	COG1749	Flagellar hook protein flgE
XBW1_2608	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
XBW1_2609	COG1558	bacterial-type flagellum-dependent cell motility
XBW1_2610	COG1815	bacterial-type flagellum-dependent cell motility
XBW1_2614	COG3539	Fimbrial protein
XBW1_2616	COG3121	Chaperone
XBW1_2619	COG1662	PFAM IS1 transposase
XBW1_2620	COG3677	Transposase
XBW1_2623	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
XBW1_2629	COG1115	amino acid carrier protein
XBW1_2643	COG3293	Transposase
XBW1_2644	COG0582	viral genome integration into host DNA
XBW1_2645	COG0582	viral genome integration into host DNA
XBW1_2651	COG3293	Transposase
XBW1_2653	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
XBW1_2654	COG0745	RESPONSE REGULATOR receiver
XBW1_2655	COG2201	protein-glutamate methylesterase activity
XBW1_2656	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
XBW1_2657	COG0840	transmembrane signaling receptor activity
XBW1_2658	COG0840	transmembrane signaling receptor activity
XBW1_2659	COG0835	chemotaxis
XBW1_2660	COG2198	Histidine kinase
XBW1_2660	COG0643	Histidine kinase
XBW1_2661	COG1360	Flagellar Motor Protein
XBW1_2671	COG1285	pathogenesis
XBW1_2673	COG1278	Cold shock
XBW1_2683	COG0418	dihydroorotase activity
XBW1_2687	COG1560	Kdo2-lipid A biosynthetic process
XBW1_2688	COG3104	oligopeptide transport
XBW1_2711	COG4626	Terminase
XBW1_2711	COG1802	Transcriptional regulator
XBW1_2717	COG1304	FMN binding
XBW1_2718	COG1620	l-lactate permease
XBW1_2721	COG3545	Serine hydrolase
XBW1_2723	COG1943	Transposase
XBW1_2733	COG1278	Cold shock
XBW1_2734	COG3604	Transcriptional regulator
XBW1_2739	COG2144	transferase activity, transferring acyl groups
XBW1_2741	COG2072	flavoprotein involved in K transport
XBW1_2742	COG3397	chitin binding
XBW1_2743	COG0346	lactoylglutathione lyase activity
XBW1_2756	COG3293	Transposase
XBW1_2758	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
XBW1_2759	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
XBW1_2761	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
XBW1_2762	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
XBW1_2765	COG0784	Response regulator, receiver
XBW1_2765	COG2205	protein histidine kinase activity
XBW1_2766	COG2197	response regulator
XBW1_2767	COG0642	Histidine kinase
XBW1_2767	COG2198	Histidine kinase
XBW1_2769	COG0814	amino acid
XBW1_2772	COG1441	menaquinone biosynthetic process
XBW1_2773	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
XBW1_2774	COG0596	Alpha beta hydrolase
XBW1_2775	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
XBW1_2779	COG5433	transposase activity
XBW1_2781	COG3121	Chaperone
XBW1_2783	COG3293	Transposase
XBW1_2787	COG3739	integral membrane protein
XBW1_2789	COG0483	inositol monophosphate 1-phosphatase activity
XBW1_2790	COG1187	pseudouridine synthase activity
XBW1_2798	COG4626	Terminase
XBW1_2798	COG1802	Transcriptional regulator
XBW1_2824	COG0582	viral genome integration into host DNA
XBW1_2853	COG3728	DNA packaging
XBW1_2853	COG5484	DNA packaging
XBW1_2866	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
XBW1_2884	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
XBW1_2885	COG0322	excinuclease ABC activity
XBW1_2886	COG2197	response regulator
XBW1_2893	COG5433	transposase activity
XBW1_2899	COG0583	DNA-binding transcription factor activity
XBW1_2902	COG1113	amino acid transport
XBW1_2911	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
XBW1_2912	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
XBW1_2912	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
XBW1_2912	COG0506	proline dehydrogenase activity
XBW1_2914	COG1191	sigma factor activity
XBW1_2939	COG5433	transposase activity
XBW1_2945	COG2076	Multidrug Resistance protein
XBW1_2946	COG0037	tRNA processing
XBW1_2947	COG0598	Magnesium transport protein CorA
XBW1_2948	COG4166	transmembrane transport
XBW1_2950	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
XBW1_2954	COG3768	UPF0283 membrane protein
XBW1_2955	COG3106	COG3106 Predicted ATPase
XBW1_2956	COG1983	PspC domain protein
XBW1_2958	COG1842	Phage shock protein A
XBW1_2959	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
XBW1_2960	COG4166	transmembrane transport
XBW1_2961	COG4168	peptide transport system, permease
XBW1_2962	COG4171	peptide transport system, permease
XBW1_2967	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
XBW1_2968	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
XBW1_2969	COG0259	pyridoxamine-phosphate oxidase activity
XBW1_2970	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
XBW1_2971	COG3133	Outer membrane lipoprotein
XBW1_2974	COG0346	lactoylglutathione lyase activity
XBW1_2975	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
XBW1_2976	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
XBW1_2977	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
XBW1_2978	COG3293	Transposase
XBW1_2979	COG1609	Transcriptional regulator
XBW1_2980	COG0583	DNA-binding transcription factor activity
XBW1_2981	COG2814	Major facilitator Superfamily
XBW1_2983	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
XBW1_2984	COG0307	riboflavin synthase, alpha
XBW1_2985	COG0534	Mate efflux family protein
XBW1_2987	COG4238	major outer membrane lipoprotein
XBW1_2988	COG1388	LysM domain
XBW1_2988	COG1376	ErfK ybiS ycfS ynhG family protein
XBW1_2989	COG2050	protein possibly involved in aromatic compounds catabolism
XBW1_2990	COG0247	lactate metabolic process
XBW1_2990	COG0277	FAD linked oxidase domain protein
XBW1_2991	COG0628	permease
XBW1_2993	COG0574	Belongs to the PEP-utilizing enzyme family
XBW1_2993	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
XBW1_2994	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
XBW1_2995	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
XBW1_2996	COG4771	TonB-dependent receptor
XBW1_2997	COG3720	iron ion transport
XBW1_2998	COG4558	Periplasmic binding protein
XBW1_2999	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
XBW1_3000	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
XBW1_3002	COG2207	Transcriptional regulator
XBW1_3003	COG0095	Lipoate-protein ligase
XBW1_3004	COG0791	NLP P60 protein
XBW1_3005	COG2076	Multidrug Resistance protein
XBW1_3006	COG2076	Multidrug Resistance protein
XBW1_3008	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
XBW1_3009	COG0726	polysaccharide deacetylase
XBW1_3010	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
XBW1_3010	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XBW1_3011	COG0463	Glycosyl transferase, family 2
XBW1_3012	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
XBW1_3013	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
XBW1_3014	COG4139	cobalamin transport
XBW1_3015	COG0776	regulation of translation
XBW1_3016	COG0072	phenylalanine-tRNA ligase activity
XBW1_3016	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
XBW1_3019	COG0291	Belongs to the bacterial ribosomal protein bL35 family
XBW1_3020	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
XBW1_3021	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
XBW1_3049	COG0484	heat shock protein binding
XBW1_3057	COG0305	Participates in initiation and elongation during chromosome replication
XBW1_3092	COG0803	Belongs to the bacterial solute-binding protein 9 family
XBW1_3093	COG1121	(ABC) transporter
XBW1_3094	COG1108	ABC-type Mn2 Zn2 transport systems permease components
XBW1_3095	COG1108	ABC-type Mn2 Zn2 transport systems permease components
XBW1_3102	COG5301	cellulose 1,4-beta-cellobiosidase activity
XBW1_3108	COG3335	DDE superfamily endonuclease
XBW1_3111	COG0642	Histidine kinase
XBW1_3113	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
XBW1_3114	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
XBW1_3115	COG0101	tRNA pseudouridine synthase activity
XBW1_3116	COG0586	Pfam SNARE associated Golgi protein
XBW1_3117	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
XBW1_3118	COG0285	dihydrofolate synthase activity
XBW1_3119	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
XBW1_3120	COG1286	toxin biosynthetic process
XBW1_3121	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
XBW1_3122	COG0163	prenyltransferase activity
XBW1_3123	COG1090	epimerase
XBW1_3124	COG0625	glutathione transferase activity
XBW1_3129	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
XBW1_3129	COG2070	2-Nitropropane dioxygenase
XBW1_3130	COG1028	Short-chain dehydrogenase reductase Sdr
XBW1_3132	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XBW1_3134	COG1131	(ABC) transporter
XBW1_3141	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
XBW1_3142	COG3138	arginine N-succinyltransferase
XBW1_3143	COG1012	belongs to the aldehyde dehydrogenase family
XBW1_3144	COG3724	N-succinylarginine dihydrolase activity
XBW1_3145	COG2988	succinylglutamate desuccinylase activity
XBW1_3146	COG1113	amino acid transport
XBW1_3147	COG0857	belongs to the CobB CobQ family
XBW1_3147	COG0280	phosphate acetyltransferase
XBW1_3149	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
XBW1_3151	COG3013	Belongs to the UPF0304 family
XBW1_3152	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
XBW1_3153	COG0471	metal ion transport
XBW1_3153	COG0490	domain, Protein
XBW1_3156	COG0436	Aminotransferase
XBW1_3158	COG0583	DNA-binding transcription factor activity
XBW1_3160	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XBW1_3161	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XBW1_3162	COG0649	NAD binding
XBW1_3162	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XBW1_3163	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
XBW1_3165	COG1034	ATP synthesis coupled electron transport
XBW1_3166	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
XBW1_3167	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XBW1_3168	COG0839	Belongs to the complex I subunit 6 family
XBW1_3169	COG0713	ATP synthesis coupled electron transport
XBW1_3170	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
XBW1_3171	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XBW1_3172	COG1007	ATP synthesis coupled electron transport
XBW1_3176	COG5433	transposase activity
XBW1_3180	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
XBW1_3181	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XBW1_3181	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
XBW1_3186	COG3101	peptidyl-lysine hydroxylation
XBW1_3187	COG0730	response to heat
XBW1_3188	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
XBW1_3189	COG2890	protein-(glutamine-N5) methyltransferase activity
XBW1_3191	COG2986	histidine ammonia-lyase
XBW1_3192	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
XBW1_3194	COG0010	Belongs to the arginase family
XBW1_3195	COG1228	amidohydrolase
XBW1_3197	COG2840	Smr protein MutS2
XBW1_3201	COG1943	Transposase
XBW1_3218	COG0740	serine-type endopeptidase activity
XBW1_3219	COG4695	Portal protein
XBW1_3250	COG0582	viral genome integration into host DNA
XBW1_3251	COG2920	part of a sulfur-relay system
XBW1_3252	COG1254	Belongs to the acylphosphatase family
XBW1_3253	COG3785	DNA binding
XBW1_3254	COG1832	CoA-binding protein
XBW1_3255	COG0210	DNA helicase
XBW1_3256	COG1289	transmembrane transporter activity
XBW1_3261	COG2814	Major facilitator Superfamily
XBW1_3264	COG3070	regulator of competence-specific genes
XBW1_3267	COG3120	sequence-specific DNA binding
XBW1_3268	COG1067	ATP-dependent peptidase activity
XBW1_3269	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
XBW1_3270	COG3009	Protein conserved in bacteria
XBW1_3271	COG3008	intermembrane lipid transfer
XBW1_3271	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
XBW1_3272	COG2995	paraquat-inducible protein a
XBW1_3273	COG0488	(ABC) transporter
XBW1_3274	COG0116	Belongs to the methyltransferase superfamily
XBW1_3274	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
XBW1_3276	COG0633	Ferredoxin
XBW1_3276	COG3217	Mosc domain protein beta barrel domain protein
XBW1_3278	COG0167	dihydroorotate dehydrogenase activity
XBW1_3279	COG0308	aminopeptidase N
XBW1_3281	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
XBW1_3282	COG0017	Asparaginyl-tRNA synthetase
XBW1_3283	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
XBW1_3285	COG1448	Aminotransferase
XBW1_3286	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XBW1_3287	COG3108	Peptidase M15
XBW1_3288	COG1943	Transposase
XBW1_3289	COG2989	Protein conserved in bacteria
XBW1_3290	COG3700	Belongs to the class B bacterial acid phosphatase family
XBW1_3291	COG0583	DNA-binding transcription factor activity
XBW1_3293	COG0585	pseudouridine synthase activity
XBW1_3294	COG0635	Involved in the biosynthesis of porphyrin-containing compound
XBW1_3298	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XBW1_3300	COG0563	adenylate kinase activity
XBW1_3303	COG1181	Belongs to the D-alanine--D-alanine ligase family
XBW1_3306	COG0667	Aldo Keto reductase
XBW1_3311	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
XBW1_3312	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
XBW1_3313	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
XBW1_3314	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
XBW1_3315	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
XBW1_3316	COG1434	Gram-negative-bacterium-type cell wall biogenesis
XBW1_3317	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
XBW1_3318	COG2835	tetraacyldisaccharide 4'-kinase activity
XBW1_3319	COG1663	tetraacyldisaccharide 4'-kinase activity
XBW1_3320	COG1132	(ABC) transporter
XBW1_3321	COG0658	competence protein
XBW1_3321	COG2333	competence protein COMEC
XBW1_3323	COG0539	negative regulation of cytoplasmic translation
XBW1_3324	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
XBW1_3325	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
XBW1_3326	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
XBW1_3329	COG0252	asparaginase activity
XBW1_3330	COG1944	ATP diphosphatase activity
XBW1_3331	COG1943	Transposase
XBW1_3332	COG2116	formate transmembrane transporter activity
XBW1_3336	COG1882	Formate acetyltransferase
XBW1_3337	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
XBW1_3340	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
XBW1_3341	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
XBW1_3342	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
XBW1_3343	COG3107	peptidoglycan biosynthetic process
XBW1_3343	COG1674	ftsk spoiiie
XBW1_3344	COG1522	sequence-specific DNA binding
XBW1_3345	COG0492	ferredoxin-NADP+ reductase activity
XBW1_3347	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
XBW1_3348	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
XBW1_3350	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
XBW1_3351	COG0542	response to heat
XBW1_3352	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
XBW1_3354	COG3293	Transposase
XBW1_3355	COG2431	L-lysine efflux transmembrane transporter activity
XBW1_3356	COG1126	abc transporter atp-binding protein
XBW1_3357	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
XBW1_3358	COG4215	(ABC) transporter
XBW1_3359	COG4160	amino acid transport
XBW1_3360	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
XBW1_3363	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
XBW1_3365	COG0671	phosphoesterase, PA-phosphatase related
XBW1_3366	COG0814	amino acid
XBW1_3367	COG1686	Belongs to the peptidase S11 family
XBW1_3368	COG0625	glutathione transferase activity
XBW1_3369	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XBW1_3371	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
XBW1_3372	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
XBW1_3372	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XBW1_3373	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
XBW1_3373	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XBW1_3374	COG0131	Imidazoleglycerol-phosphate dehydratase
XBW1_3374	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
XBW1_3375	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
XBW1_3376	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
XBW1_3377	COG0107	imidazoleglycerol-phosphate synthase activity
XBW1_3378	COG0140	phosphoribosyl-ATP diphosphatase activity
XBW1_3378	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
XBW1_3379	COG1454	alcohol dehydrogenase
XBW1_3382	COG5433	transposase activity
XBW1_3385	COG5433	transposase activity
XBW1_3386	COG1253	flavin adenine dinucleotide binding
XBW1_3387	COG5301	cellulose 1,4-beta-cellobiosidase activity
XBW1_3388	COG5301	cellulose 1,4-beta-cellobiosidase activity
XBW1_3389	COG2982	Protein involved in outer membrane biogenesis
XBW1_3390	COG0717	Belongs to the dCTP deaminase family
XBW1_3391	COG0572	uridine kinase
XBW1_3392	COG0489	protein tyrosine kinase activity
XBW1_3393	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
XBW1_3393	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
XBW1_3394	COG1380	Effector of murein hydrolase LrgA
XBW1_3396	COG1346	cytolysis
XBW1_3397	COG0295	cytidine deaminase activity
XBW1_3398	COG0281	malic enzyme
XBW1_3399	COG2949	membrane
XBW1_3400	COG2311	Membrane
XBW1_3401	COG0302	gtp cyclohydrolase
XBW1_3402	COG0477	Major facilitator Superfamily
XBW1_3403	COG0303	'Molybdopterin
XBW1_3404	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
XBW1_3409	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
XBW1_3410	COG0488	(ABC) transporter
XBW1_3412	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
XBW1_3413	COG0561	phosphatase activity
XBW1_3433	COG5006	permease, DMT superfamily
XBW1_3435	COG2824	Alkylphosphonate utilization operon protein PhnA
XBW1_3436	COG1943	Transposase
XBW1_3440	COG1131	(ABC) transporter
XBW1_3443	COG2897	thiosulfate sulfurtransferase activity
XBW1_3444	COG2261	transglycosylase associated protein
XBW1_3445	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
XBW1_3446	COG0513	Belongs to the DEAD box helicase family
XBW1_3447	COG1309	transcriptional regulator
XBW1_3449	COG1131	(ABC) transporter
XBW1_3450	COG0842	Transport permease protein
XBW1_3451	COG0842	Transport permease protein
XBW1_3452	COG0670	Belongs to the BI1 family
XBW1_3453	COG0314	molybdopterin synthase activity
XBW1_3454	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
XBW1_3455	COG0315	cyclic pyranopterin monophosphate synthase activity
XBW1_3456	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
XBW1_3457	COG0391	Required for morphogenesis under gluconeogenic growth conditions
XBW1_3458	COG0556	nucleotide-excision repair
XBW1_3461	COG2226	methyltransferase
XBW1_3462	COG0156	8-amino-7-oxononanoate synthase activity
XBW1_3463	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
XBW1_3464	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
XBW1_3466	COG2706	6-phosphogluconolactonase activity
XBW1_3467	COG0561	phosphatase activity
XBW1_3468	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
XBW1_3469	COG4149	molybdate abc transporter
XBW1_3470	COG0725	ABC transporter, periplasmic molybdate-binding protein
XBW1_3473	COG3585	molybdate ion transport
XBW1_3473	COG2005	Transcriptional regulator
XBW1_3474	COG1119	ATPase activity
XBW1_3477	COG0588	phosphoglycerate mutase activity
XBW1_3478	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
XBW1_3481	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
XBW1_3482	COG2885	chlorophyll binding
XBW1_3483	COG0823	Involved in the tonB-independent uptake of proteins
XBW1_3484	COG3064	Membrane
XBW1_3484	COG3064	Membrane
XBW1_3485	COG0848	biopolymer transport protein
XBW1_3486	COG0811	peptide transport
XBW1_3487	COG0824	Thioesterase
XBW1_3488	COG3790	cyd operon protein YbgE
XBW1_3490	COG1294	oxidase, subunit
XBW1_3491	COG1271	oxidase subunit
XBW1_3492	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
XBW1_3493	COG0045	succinate-CoA ligase (ADP-forming) activity
XBW1_3494	COG0508	dehydrogenase complex catalyzes the overall conversion of
XBW1_3495	COG0567	Dehydrogenase, E1 component
XBW1_3497	COG1053	succinate dehydrogenase
XBW1_3498	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
XBW1_3499	COG2009	succinate dehydrogenase
XBW1_3500	COG0372	Belongs to the citrate synthase family
XBW1_3502	COG2814	Major facilitator Superfamily
XBW1_3503	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
XBW1_3505	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
XBW1_3506	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
XBW1_3507	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
XBW1_3508	COG2205	protein histidine kinase activity
XBW1_3509	COG0745	RESPONSE REGULATOR receiver
XBW1_3512	COG0033	Phosphoglucomutase
XBW1_3513	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
XBW1_3514	COG0596	Alpha beta hydrolase
XBW1_3517	COG3293	Transposase
XBW1_3523	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
XBW1_3523	COG1073	alpha beta
XBW1_3523	COG3064	Membrane
XBW1_3525	COG2994	toxin metabolic process
XBW1_3531	COG4977	sequence-specific DNA binding
XBW1_3534	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XBW1_3540	COG5433	transposase activity
XBW1_3544	COG0716	FMN binding
XBW1_3545	COG0735	belongs to the Fur family
XBW1_3547	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
XBW1_3548	COG3293	Transposase
XBW1_3553	COG2190	(PTS) system
XBW1_3553	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
XBW1_3553	COG1263	PTS System
XBW1_3554	COG0363	glucosamine-6-phosphate deaminase activity
XBW1_3555	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
XBW1_3556	COG1846	Transcriptional regulator
XBW1_3556	COG1940	carbohydrate kinase activity
XBW1_3558	COG2814	Major facilitator Superfamily
XBW1_3560	COG3293	Transposase
XBW1_3562	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XBW1_3563	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
XBW1_3564	COG1702	phosphate starvation-inducible protein PhoH
XBW1_3565	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
XBW1_3566	COG4535	Mg2 and Co2 transporter CorC
XBW1_3567	COG0815	Transfers the fatty acyl group on membrane lipoproteins
XBW1_3569	COG0765	amino acid transport
XBW1_3570	COG0765	amino acid transport
XBW1_3571	COG1126	abc transporter atp-binding protein
XBW1_3572	COG0495	leucyl-tRNA aminoacylation
XBW1_3573	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
XBW1_3574	COG1466	dna polymerase III delta subunit
XBW1_3576	COG0799	negative regulation of ribosome biogenesis
XBW1_3577	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
XBW1_3578	COG0768	penicillin binding
XBW1_3579	COG0772	Belongs to the SEDS family
XBW1_3580	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
XBW1_3582	COG1686	Belongs to the peptidase S11 family
XBW1_3583	COG2921	Belongs to the UPF0250 family
XBW1_3585	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
XBW1_3586	COG0321	lipoyl(octanoyl) transferase activity
XBW1_3587	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
XBW1_3588	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
XBW1_3589	COG1278	Cold shock
XBW1_3590	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
XBW1_3593	COG4175	Glycine betaine
XBW1_3594	COG4176	ABC-type proline glycine betaine transport system permease component
XBW1_3595	COG2113	Glycine betaine
XBW1_3596	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
XBW1_3598	COG1846	Transcriptional regulator
XBW1_3599	COG1566	PFAM secretion protein HlyD family protein
XBW1_3600	COG2814	Major facilitator Superfamily
XBW1_3604	COG3486	L-lysine 6-monooxygenase (NADPH) activity
XBW1_3606	COG4114	ferric iron reductase
XBW1_3607	COG1120	ATPase activity
XBW1_3608	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
XBW1_3609	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
XBW1_3610	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
XBW1_3611	COG4773	Receptor
XBW1_3613	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
XBW1_3617	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XBW1_3619	COG5544	Lipoprotein
XBW1_3625	COG0542	response to heat
XBW1_3627	COG0564	pseudouridine synthase activity
XBW1_3628	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XBW1_3629	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
XBW1_3630	COG1605	Chorismate mutase
XBW1_3630	COG0077	Prephenate dehydratase
XBW1_3631	COG1605	Chorismate mutase
XBW1_3631	COG0287	Prephenate dehydrogenase
XBW1_3632	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
XBW1_3635	COG0335	large ribosomal subunit rRNA binding
XBW1_3636	COG0336	Belongs to the RNA methyltransferase TrmD family
XBW1_3637	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
XBW1_3638	COG0228	four-way junction DNA binding
XBW1_3639	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
XBW1_3640	COG4137	Cytochrome C assembly protein
XBW1_3641	COG4536	flavin adenine dinucleotide binding
XBW1_3642	COG1854	S-ribosylhomocysteine lyase activity
XBW1_3643	COG2918	glutathione biosynthetic process
XBW1_3645	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
XBW1_3646	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
XBW1_3649	COG2814	Major facilitator Superfamily
XBW1_3650	COG0204	Acyl-transferase
XBW1_3650	COG0318	PFAM AMP-dependent synthetase and ligase
XBW1_3651	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
XBW1_3652	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
XBW1_3653	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
XBW1_3656	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
XBW1_3657	COG2195	Cleaves the N-terminal amino acid of tripeptides
XBW1_3658	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
XBW1_3660	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
XBW1_3661	COG1309	transcriptional regulator
XBW1_3662	COG1012	belongs to the aldehyde dehydrogenase family
XBW1_3663	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
XBW1_3666	COG1629	transport
XBW1_3667	COG1595	DNA-templated transcription, initiation
XBW1_3669	COG2991	Protein conserved in bacteria
XBW1_3670	COG1477	protein flavinylation
XBW1_3672	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
XBW1_3673	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
XBW1_3674	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
XBW1_3675	COG1805	sodium ion transport
XBW1_3676	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
XBW1_3677	COG3034	peptidoglycan biosynthetic process
XBW1_3678	COG0121	glutamine amidotransferase
XBW1_3679	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
XBW1_3680	COG1960	acyl-CoA dehydrogenase activity
XBW1_3681	COG0019	diaminopimelate decarboxylase activity
XBW1_3682	COG0583	DNA-binding transcription factor activity
XBW1_3683	COG0583	DNA-binding transcription factor activity
XBW1_3689	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
XBW1_3690	COG1385	rRNA (uridine-N3-)-methyltransferase activity
XBW1_3691	COG0189	ligase activity
XBW1_3692	COG1678	Uncharacterized ACR, COG1678
XBW1_3693	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
XBW1_3694	COG2805	Type II/IV secretion system protein
XBW1_3695	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
XBW1_3696	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
XBW1_3697	COG0762	integral membrane protein
XBW1_3698	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
XBW1_3699	COG0635	Involved in the biosynthesis of porphyrin-containing compound
XBW1_3700	COG4607	ABC-type enterochelin transport system periplasmic component
XBW1_3702	COG2066	Belongs to the glutaminase family
XBW1_3703	COG3171	Protein conserved in bacteria
XBW1_3704	COG0220	tRNA (guanine-N7-)-methyltransferase activity
XBW1_3705	COG1194	a g-specific adenine glycosylase
XBW1_3706	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
XBW1_3707	COG0741	lytic transglycosylase activity
XBW1_3709	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
XBW1_3733	COG3335	DDE superfamily endonuclease
XBW1_3737	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
XBW1_3739	COG3335	DDE superfamily endonuclease
XBW1_3746	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
XBW1_3751	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
XBW1_3758	COG0305	Participates in initiation and elongation during chromosome replication
XBW1_3762	COG0305	Participates in initiation and elongation during chromosome replication
XBW1_3769	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
XBW1_3770	COG1943	Transposase
XBW1_3822	COG3335	DDE superfamily endonuclease
XBW1_3828	COG1114	Component of the transport system for branched-chain amino acids
XBW1_3829	COG0733	neurotransmitter:sodium symporter activity
XBW1_3833	COG3293	Transposase
XBW1_3835	COG0501	Belongs to the peptidase M48B family
XBW1_3851	COG0443	Heat shock 70 kDa protein
XBW1_3859	COG5433	transposase activity
XBW1_3860	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
XBW1_3861	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
XBW1_3862	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
XBW1_3863	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
XBW1_3864	COG4974	Belongs to the 'phage' integrase family
XBW1_3865	COG0716	FMN binding
XBW1_3867	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
XBW1_3868	COG0354	folic acid binding
XBW1_3870	COG0477	Major facilitator Superfamily
XBW1_3871	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
XBW1_3871	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
XBW1_3872	COG0509	glycine decarboxylation via glycine cleavage system
XBW1_3873	COG0404	The glycine cleavage system catalyzes the degradation of glycine
XBW1_3874	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XBW1_3875	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XBW1_3876	COG0006	proline dipeptidase activity
XBW1_3877	COG3079	Belongs to the UPF0149 family
XBW1_3879	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
XBW1_3880	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
XBW1_3881	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
XBW1_3882	COG0583	DNA-binding transcription factor activity
XBW1_3885	COG1279	arginine transmembrane transporter activity
XBW1_3886	COG0668	transmembrane transport
XBW1_3887	COG3112	Uncharacterised protein family (UPF0231)
XBW1_3889	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XBW1_3890	COG0508	dehydrogenase complex catalyzes the overall conversion of
XBW1_3891	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
XBW1_3892	COG2186	Transcriptional regulator
XBW1_3893	COG3725	Membrane protein required for beta-lactamase induction
XBW1_3894	COG3023	N-Acetylmuramoyl-L-alanine amidase
XBW1_3895	COG4969	Belongs to the N-Me-Phe pilin family
XBW1_3896	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
XBW1_3898	COG0237	dephospho-CoA kinase activity
XBW1_3899	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
XBW1_3900	COG0494	nUDIX hydrolase
XBW1_3901	COG0488	(ABC) transporter
XBW1_3902	COG0653	protein targeting
XBW1_3905	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
XBW1_3907	COG0849	cell division
XBW1_3908	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
XBW1_3909	COG1181	Belongs to the D-alanine--D-alanine ligase family
XBW1_3910	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
XBW1_3911	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
XBW1_3912	COG0772	Belongs to the SEDS family
XBW1_3913	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
XBW1_3914	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
XBW1_3915	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
XBW1_3916	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
XBW1_3917	COG0768	penicillin binding
XBW1_3918	COG3116	cell division
XBW1_3919	COG0275	rRNA processing
XBW1_3920	COG2001	Belongs to the MraZ family
XBW1_3921	COG1609	Transcriptional regulator
XBW1_3923	COG0028	Belongs to the TPP enzyme family
XBW1_3924	COG1022	Amp-dependent synthetase and ligase
XBW1_3927	COG0473	3-isopropylmalate dehydrogenase activity
XBW1_3928	COG3066	DNA modification
XBW1_3930	COG0242	peptide deformylase activity
XBW1_3931	COG0626	cystathionine gamma-synthase activity
XBW1_3936	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
XBW1_3940	COG0066	3-isopropylmalate dehydratase activity
XBW1_3941	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
XBW1_3942	COG0583	DNA-binding transcription factor activity
XBW1_3944	COG1881	PFAM PEBP family protein
XBW1_3945	COG0010	Belongs to the arginase family
XBW1_3946	COG1166	arginine decarboxylase activity
XBW1_3947	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
XBW1_3948	COG3091	SprT-like family
XBW1_3953	COG1301	dicarboxylic acid transport
XBW1_3955	COG0471	metal ion transport
XBW1_3956	COG0148	phosphopyruvate hydratase activity
XBW1_3957	COG0504	CTP synthase activity
XBW1_3958	COG3956	TIGRFAM MazG family protein
XBW1_3959	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
XBW1_3960	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
XBW1_3962	COG0232	Belongs to the dGTPase family. Type 2 subfamily
XBW1_3963	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
XBW1_3964	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
XBW1_3965	COG0316	Belongs to the HesB IscA family
XBW1_3966	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
XBW1_3971	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
XBW1_3972	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
XBW1_3981	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
XBW1_3982	COG1643	Atp-dependent helicase
XBW1_3983	COG1489	DNA binding
XBW1_3984	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
XBW1_3985	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
XBW1_3987	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
XBW1_3988	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
XBW1_3989	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
XBW1_3990	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
XBW1_3991	COG0842	Transport permease protein
XBW1_3992	COG1131	(ABC) transporter
XBW1_3993	COG0288	reversible hydration of carbon dioxide
XBW1_3995	COG3423	Transcriptional regulator
XBW1_4005	COG2423	ornithine cyclodeaminase activity
XBW1_4010	COG3842	ATPase activity
XBW1_4011	COG0534	Mate efflux family protein
XBW1_4017	COG0814	amino acid
XBW1_4019	COG0582	viral genome integration into host DNA
XBW1_4020	COG0523	cobalamin synthesis protein
XBW1_4021	COG2879	small protein
XBW1_4022	COG1966	Carbon starvation protein
XBW1_4023	COG2194	sulfuric ester hydrolase activity
XBW1_4024	COG3012	SEC-C Motif Domain Protein
XBW1_4025	COG3335	DDE superfamily endonuclease
XBW1_4029	COG1278	Cold shock
XBW1_4034	COG2015	COG2015, Alkyl sulfatase and related hydrolases
XBW1_4036	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
XBW1_4038	COG1388	LysM domain
XBW1_4038	COG4942	peptidase
XBW1_4039	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
XBW1_4040	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
XBW1_4041	COG0585	pseudouridine synthase activity
XBW1_4042	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
XBW1_4043	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
XBW1_4047	COG2895	sulfate adenylyltransferase (ATP) activity
XBW1_4048	COG0175	sulfate reduction
XBW1_4049	COG1648	precorrin-2 dehydrogenase activity
XBW1_4049	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
XBW1_4050	COG0175	sulfate reduction
XBW1_4051	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
XBW1_4052	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
XBW1_4053	COG0720	synthase
XBW1_4054	COG0602	queuosine metabolic process
XBW1_4056	COG3021	interspecies interaction between organisms
XBW1_4061	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
XBW1_4062	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
XBW1_4063	COG1739	Uncharacterized protein family UPF0029
XBW1_4064	COG0006	proline dipeptidase activity
XBW1_4065	COG1024	Enoyl-CoA hydratase
XBW1_4065	COG1250	3-hydroxyacyl-CoA dehydrogenase
XBW1_4066	COG0183	Belongs to the thiolase family
XBW1_4068	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
XBW1_4071	COG0805	protein transport
XBW1_4072	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
XBW1_4073	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
XBW1_4074	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
XBW1_4075	COG3165	ubiquinone biosynthetic process from chorismate
XBW1_4076	COG2226	methyltransferase
XBW1_4079	COG0586	Pfam SNARE associated Golgi protein
XBW1_4081	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
XBW1_4083	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
XBW1_4084	COG0583	DNA-binding transcription factor activity
XBW1_4085	COG0697	spore germination
XBW1_4086	COG0025	NhaP-type Na H and K H
XBW1_4087	COG2252	PERMEase
XBW1_4092	COG3293	Transposase
XBW1_4097	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
XBW1_4098	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XBW1_4103	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
XBW1_4105	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
XBW1_4111	COG1448	Aminotransferase
XBW1_4112	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
XBW1_4113	COG0305	Participates in initiation and elongation during chromosome replication
XBW1_4115	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
XBW1_4120	COG0735	belongs to the Fur family
XBW1_4122	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
XBW1_4123	COG2937	Belongs to the GPAT DAPAT family
XBW1_4124	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
XBW1_4125	COG3161	chorismate lyase activity
XBW1_4126	COG0166	Belongs to the GPI family
XBW1_4127	COG0527	aspartate kinase activity
XBW1_4128	COG1414	Transcriptional regulator
XBW1_4129	COG0800	Aldolase
XBW1_4131	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
XBW1_4132	COG2224	Isocitrate lyase
XBW1_4133	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
XBW1_4134	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
XBW1_4140	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
XBW1_4141	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
XBW1_4143	COG1464	Belongs to the NlpA lipoprotein family
XBW1_4145	COG1720	tRNA m6t6A37 methyltransferase activity
XBW1_4146	COG0442	prolyl-tRNA aminoacylation
XBW1_4147	COG3015	lipoprotein NlpE involved in copper resistance
XBW1_4148	COG4568	rho-dependent transcription termination
XBW1_4154	COG0037	tRNA processing
XBW1_4155	COG0697	spore germination
XBW1_4156	COG0825	malonyl-CoA metabolic process
XBW1_4158	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
XBW1_4159	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XBW1_4160	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XBW1_4161	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
XBW1_4162	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XBW1_4165	COG0750	zinc metalloprotease
XBW1_4166	COG0575	Belongs to the CDS family
XBW1_4167	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
XBW1_4168	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
XBW1_4169	COG0233	cytoplasmic translational termination
XBW1_4170	COG0528	UMP kinase activity
XBW1_4171	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
XBW1_4172	COG0052	Belongs to the universal ribosomal protein uS2 family
XBW1_4173	COG0024	Methionine aminopeptidase
XBW1_4174	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
XBW1_4179	COG3098	single-species biofilm formation
XBW1_4187	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
XBW1_4187	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
XBW1_4188	COG1611	Belongs to the LOG family
XBW1_4189	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
XBW1_4195	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
XBW1_4196	COG2363	Small membrane protein
XBW1_4197	COG0583	DNA-binding transcription factor activity
XBW1_4198	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
XBW1_4199	COG2166	iron-sulfur cluster assembly
XBW1_4200	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
XBW1_4201	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
XBW1_4204	COG0860	N-Acetylmuramoyl-L-alanine amidase
XBW1_4205	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
XBW1_4205	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
XBW1_4206	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
XBW1_4207	COG1074	ATP-dependent DNA helicase activity
XBW1_4209	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
XBW1_4212	COG4795	General secretion pathway protein
XBW1_4214	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
XBW1_4215	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
XBW1_4217	COG0494	nUDIX hydrolase
XBW1_4218	COG4143	(ABC) transporter
XBW1_4219	COG1178	ABC-type Fe3 transport system permease component
XBW1_4220	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
XBW1_4221	COG3293	Transposase
XBW1_4230	COG2992	FlgJ-related protein
XBW1_4235	COG2610	gluconate transmembrane transporter activity
XBW1_4236	COG3265	gluconokinase activity
XBW1_4237	COG1609	Transcriptional regulator
XBW1_4239	COG1486	melibiose metabolic process
XBW1_4241	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
XBW1_4245	COG1309	transcriptional regulator
XBW1_4246	COG2814	Major facilitator Superfamily
XBW1_4247	COG1028	Short-chain dehydrogenase reductase Sdr
XBW1_4250	COG3316	Transposase and inactivated derivatives
XBW1_4255	COG1203	CRISPR-associated helicase, Cas3
XBW1_4265	COG1846	Transcriptional regulator
XBW1_4267	COG2873	o-acetylhomoserine
XBW1_4275	COG1943	Transposase
XBW1_4278	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
XBW1_4282	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
XBW1_4284	COG1177	transmembrane transport
XBW1_4285	COG1176	ABC-type spermidine putrescine transport system, permease component I
XBW1_4288	COG1105	Belongs to the carbohydrate kinase PfkB family
XBW1_4288	COG1105	Belongs to the carbohydrate kinase PfkB family
XBW1_4289	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
XBW1_4289	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
XBW1_4289	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
XBW1_4295	COG3093	addiction module antidote protein HigA
XBW1_4297	COG0583	DNA-binding transcription factor activity
XBW1_4298	COG1301	dicarboxylic acid transport
XBW1_4312	COG1943	Transposase
XBW1_4317	COG0582	viral genome integration into host DNA
XBW1_4318	COG0582	viral genome integration into host DNA
XBW1_4321	COG3423	Transcriptional regulator
XBW1_4325	COG3293	Transposase
XBW1_4329	COG3293	Transposase
XBW1_4332	COG0582	viral genome integration into host DNA
XBW1_4334	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
XBW1_4335	COG0795	lipopolysaccharide-transporting ATPase activity
XBW1_4336	COG0795	lipopolysaccharide-transporting ATPase activity
XBW1_4337	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
XBW1_4338	COG2927	DNA polymerase III (CHI subunit)
XBW1_4339	COG0525	valine-tRNA ligase activity
XBW1_4340	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
XBW1_4343	COG0765	amino acid transport
XBW1_4344	COG1126	abc transporter atp-binding protein
XBW1_4345	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
XBW1_4347	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
XBW1_4348	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
XBW1_4349	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XBW1_4350	COG2175	clavaminate synthase activity
XBW1_4352	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
XBW1_4359	COG1280	lysine exporter protein (LysE YggA)
XBW1_4360	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
XBW1_4361	COG3541	Predicted nucleotidyltransferase
XBW1_4362	COG1690	Belongs to the RtcB family
XBW1_4364	COG4650	regulator
XBW1_4370	COG0512	Glutamine amidotransferase of anthranilate synthase
XBW1_4372	COG1028	Short-chain dehydrogenase reductase Sdr
XBW1_4378	COG0540	Belongs to the ATCase OTCase family
XBW1_4381	COG5505	Protein of unknown function (DUF819)
XBW1_4384	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
XBW1_4386	COG3787	Belongs to the UPF0306 family
XBW1_4388	COG2827	Endonuclease containing a URI domain
XBW1_4389	COG3153	acetyltransferase
XBW1_4395	COG2814	Major facilitator Superfamily
XBW1_4397	COG1028	Short-chain dehydrogenase reductase Sdr
XBW1_4398	COG1028	Short-chain dehydrogenase reductase Sdr
XBW1_4399	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
XBW1_4404	COG2373	Large extracellular alpha-helical protein
XBW1_4404	COG1388	LysM domain
XBW1_4404	COG4932	domain protein
XBW1_4405	COG3275	phosphorelay sensor kinase activity
XBW1_4408	COG0513	Belongs to the DEAD box helicase family
XBW1_4411	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
XBW1_4412	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
XBW1_4413	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
XBW1_4414	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
XBW1_4415	COG0195	Participates in both transcription termination and antitermination
XBW1_4416	COG0779	Required for maturation of 30S ribosomal subunits
XBW1_4417	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
XBW1_4418	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
XBW1_4419	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
XBW1_4420	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
XBW1_4421	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
XBW1_4422	COG1534	Rna-binding protein
XBW1_4423	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XBW1_4425	COG2027	D-alanyl-D-alanine carboxypeptidase
XBW1_4426	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
XBW1_4429	COG0261	This protein binds to 23S rRNA in the presence of protein L20
XBW1_4430	COG0142	geranyltranstransferase activity
XBW1_4433	COG3423	Transcriptional regulator
XBW1_4434	COG0039	L-malate dehydrogenase activity
XBW1_4436	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
XBW1_4437	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
XBW1_4438	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
XBW1_4439	COG2105	PFAM AIG2 family protein
XBW1_4442	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
XBW1_4443	COG1253	flavin adenine dinucleotide binding
XBW1_4445	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
XBW1_4447	COG0545	Peptidyl-prolyl cis-trans isomerase
XBW1_4450	COG2965	DNA replication, synthesis of RNA primer
XBW1_4451	COG0360	Binds together with S18 to 16S ribosomal RNA
XBW1_4452	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
XBW1_4453	COG0557	exoribonuclease II activity
XBW1_4454	COG1959	2 iron, 2 sulfur cluster binding
XBW1_4455	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
XBW1_4456	COG0330	HflC and HflK could
XBW1_4457	COG0330	HflC and HflK could
XBW1_4460	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
XBW1_4461	COG1923	regulation of RNA biosynthetic process
XBW1_4462	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
XBW1_4463	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
XBW1_4464	COG0860	N-Acetylmuramoyl-L-alanine amidase
XBW1_4465	COG0802	atpase or kinase
XBW1_4466	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
XBW1_4467	COG2368	4-hydroxyphenylacetate
XBW1_4469	COG0154	amidase activity
XBW1_4471	COG2814	Major facilitator Superfamily
XBW1_4474	COG0583	DNA-binding transcription factor activity
XBW1_4476	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XBW1_4482	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
XBW1_4484	COG1162	GTPase activity
XBW1_4485	COG0688	phosphatidylethanolamine metabolic process
XBW1_4486	COG3264	Mechanosensitive ion channel
XBW1_4486	COG1511	domain protein
XBW1_4489	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
XBW1_4490	COG3152	Membrane
XBW1_4491	COG1609	Transcriptional regulator
XBW1_4492	COG0477	Major facilitator Superfamily
XBW1_4493	COG0561	phosphatase activity
XBW1_4494	COG2267	carboxylic ester hydrolase activity
XBW1_4495	COG0514	ATP-dependent DNA helicase (RecQ)
XBW1_4498	COG2050	protein possibly involved in aromatic compounds catabolism
XBW1_4503	COG0598	Magnesium transport protein CorA
XBW1_4504	COG0210	DNA helicase
XBW1_4505	COG1011	Hydrolase
XBW1_4507	COG3159	Protein conserved in bacteria
XBW1_4508	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
XBW1_4509	COG5567	small periplasmic lipoprotein
XBW1_4510	COG1965	Belongs to the frataxin family
XBW1_4511	COG1943	Transposase
XBW1_4516	COG0181	hydroxymethylbilane synthase activity
XBW1_4518	COG2959	enzyme of heme biosynthesis
XBW1_4519	COG3071	HemY protein
XBW1_4521	COG1113	amino acid transport
XBW1_4522	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
XBW1_4524	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
XBW1_4525	COG2244	polysaccharide biosynthetic process
XBW1_4526	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
XBW1_4527	COG0456	acetyltransferase
XBW1_4528	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
XBW1_4529	COG1088	dTDP-glucose 4,6-dehydratase activity
XBW1_4530	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
XBW1_4531	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
XBW1_4533	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
XBW1_4534	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
XBW1_4535	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
XBW1_4538	COG3118	belongs to the thioredoxin family
XBW1_4540	COG0513	Belongs to the DEAD box helicase family
XBW1_4541	COG0248	Ppx GppA phosphatase
XBW1_4542	COG0210	DNA helicase
XBW1_4544	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
XBW1_4545	COG0583	DNA-binding transcription factor activity
XBW1_4547	COG0129	dihydroxy-acid dehydratase activity
XBW1_4548	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
XBW1_4549	COG3978	acetolactate synthase activity
XBW1_4554	COG3085	chromosome segregation
XBW1_4555	COG0583	DNA-binding transcription factor activity
XBW1_4559	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
XBW1_4561	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
XBW1_4562	COG0009	L-threonylcarbamoyladenylate synthase
XBW1_4563	COG0551	DNA topoisomerase type I activity
XBW1_4564	COG0758	DNA mediated transformation
XBW1_4565	COG0242	peptide deformylase activity
XBW1_4566	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
XBW1_4567	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
XBW1_4567	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
XBW1_4568	COG0569	domain protein
XBW1_4569	COG3036	rescue of stalled ribosome
XBW1_4570	COG0789	Transcriptional regulator
XBW1_4571	COG0203	ribosomal protein L17
XBW1_4572	COG0202	RNA polymerase activity
XBW1_4573	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
XBW1_4575	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
XBW1_4577	COG0201	protein transport
XBW1_4578	COG0200	Binds to the 23S rRNA
XBW1_4579	COG1841	ribosomal large subunit assembly
XBW1_4580	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
XBW1_4581	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
XBW1_4582	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
XBW1_4583	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
XBW1_4584	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
XBW1_4585	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
XBW1_4587	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
XBW1_4588	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
XBW1_4589	COG0255	Belongs to the universal ribosomal protein uL29 family
XBW1_4590	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
XBW1_4592	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
XBW1_4593	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
XBW1_4594	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
XBW1_4595	COG0089	rRNA binding
XBW1_4596	COG0088	Forms part of the polypeptide exit tunnel
XBW1_4597	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
XBW1_4598	COG0051	transcription antitermination factor activity, RNA binding
XBW1_4604	COG1072	(Pantothenic acid kinase))
XBW1_4606	COG0812	UDP-N-acetylmuramate dehydrogenase activity
XBW1_4611	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
XBW1_4612	COG4206	TonB-dependent receptor
XBW1_4613	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
XBW1_4615	COG1309	transcriptional regulator
XBW1_4616	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XBW1_4618	COG0165	Argininosuccinate lyase
XBW1_4619	COG0137	argininosuccinate synthase activity
XBW1_4620	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
XBW1_4621	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
XBW1_4622	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XBW1_4627	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
XBW1_4628	COG0527	aspartate kinase activity
XBW1_4628	COG0460	homoserine dehydrogenase
XBW1_4629	COG0626	cystathionine gamma-synthase activity
XBW1_4631	COG0254	rRNA binding
XBW1_4632	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
XBW1_4633	COG1609	Transcriptional regulator
XBW1_4634	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
XBW1_4635	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
XBW1_4636	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
XBW1_4637	COG1575	Belongs to the MenA family. Type 1 subfamily
XBW1_4638	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
XBW1_4639	COG3074	FtsZ-dependent cytokinesis
XBW1_4642	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
XBW1_4643	COG2814	Major facilitator Superfamily
XBW1_4645	COG3152	Membrane
XBW1_4647	COG0149	triose-phosphate isomerase activity
XBW1_4648	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
XBW1_4649	COG0205	6-phosphofructokinase activity
XBW1_4650	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
XBW1_4651	COG4589	Belongs to the CDS family
XBW1_4657	COG3678	ATP-independent chaperone mediated protein folding
XBW1_4658	COG0745	RESPONSE REGULATOR receiver
XBW1_4659	COG2205	protein histidine kinase activity
XBW1_4661	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XBW1_4664	COG3475	LICD family
XBW1_4667	COG1216	Glycosyl transferase, family 2
XBW1_4667	COG1442	glycosyl transferase family 8
XBW1_4670	COG0438	transferase activity, transferring glycosyl groups
XBW1_4675	COG3335	DDE superfamily endonuclease
XBW1_4676	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
XBW1_4677	COG1045	serine acetyltransferase
XBW1_4678	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
XBW1_4679	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
XBW1_4680	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
XBW1_4681	COG4942	peptidase
XBW1_4682	COG2861	carbohydrate metabolic process
XBW1_4683	COG1063	alcohol dehydrogenase
XBW1_4684	COG0156	8-amino-7-oxononanoate synthase activity
XBW1_4685	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XBW1_4687	COG0859	PFAM glycosyl transferase family 9
XBW1_4690	COG0859	PFAM glycosyl transferase family 9
XBW1_4691	COG0438	transferase activity, transferring glycosyl groups
XBW1_4692	COG0438	transferase activity, transferring glycosyl groups
XBW1_4693	COG0859	PFAM glycosyl transferase family 9
XBW1_4695	COG1519	Transferase
XBW1_4697	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
XBW1_4698	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
XBW1_4701	COG0438	transferase activity, transferring glycosyl groups
XBW1_4703	COG0438	transferase activity, transferring glycosyl groups
XBW1_4704	COG0267	Belongs to the bacterial ribosomal protein bL33 family
XBW1_4707	COG2003	Belongs to the UPF0758 family
XBW1_4708	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
XBW1_4709	COG0756	dUTP diphosphatase activity
XBW1_4710	COG1309	transcriptional regulator
XBW1_4711	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
XBW1_4712	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
XBW1_4713	COG1561	YicC-like family, N-terminal region
XBW1_4729	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XBW1_4731	COG2188	Transcriptional regulator
XBW1_4735	COG1368	sulfuric ester hydrolase activity
XBW1_4736	COG3276	selenocysteine insertion sequence binding
XBW1_4737	COG1921	L-seryl-tRNASec selenium transferase activity
XBW1_4738	COG3058	Necessary for formate dehydrogenase activity
XBW1_4744	COG3311	Transcriptional regulator
XBW1_4749	COG3383	formate dehydrogenase (NAD+) activity
XBW1_4749	COG0243	molybdopterin cofactor binding
XBW1_4752	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
XBW1_4758	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
XBW1_4759	COG2249	NAD(P)H dehydrogenase (quinone) activity
XBW1_4760	COG1028	Short-chain dehydrogenase reductase Sdr
XBW1_4764	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
XBW1_4770	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
XBW1_4771	COG3335	DDE superfamily endonuclease
XBW1_4772	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
XBW1_4773	COG0706	membrane insertase activity
XBW1_4774	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
XBW1_4775	COG0594	ribonuclease P activity
XBW1_4776	COG0230	Belongs to the bacterial ribosomal protein bL34 family
XBW1_CDS3306568R	COG4890	Cyd operon protein YbgT
XBW1_mp0004	COG3316	Transposase and inactivated derivatives
XBW1_mp0007	COG3316	Transposase and inactivated derivatives
XBW1_mp0009	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
XBW1_mp0017	COG0667	Aldo Keto reductase
XBW1_mp0019	COG0442	prolyl-tRNA aminoacylation
XBW1_mp0020	COG0495	leucyl-tRNA aminoacylation
XBW1_mp0023	COG0813	purine-nucleoside phosphorylase activity
XBW1_mp0024	COG1619	proteins homologs of microcin C7 resistance protein MccF
XBW1_mp0025	COG2226	methyltransferase
XBW1_mp0026	COG0017	Asparaginyl-tRNA synthetase
XBW1_mp0037	COG0641	radical SAM
XBW1_mp0073	COG3335	DDE superfamily endonuclease
XBW1_mp0087	COG3501	Rhs element vgr protein
XBW1_mp0103	COG3501	Rhs element vgr protein
XBW1_mp0118	COG0675	Transposase, IS605 OrfB family
XBW1_mp0120	COG5433	transposase activity
XBW1_mp0124	COG3335	DDE superfamily endonuclease
XBW1_mp0144	COG2944	sequence-specific DNA binding
XBW1_mp0147	COG0338	D12 class N6 adenine-specific DNA methyltransferase
XBW1_mp0148	COG2974	May be involved in recombination
XBW1_mp0161	COG3657	addiction module killer protein
XBW1_mp0166	COG3316	Transposase and inactivated derivatives
XBW1_mp0175	COG0436	Aminotransferase
XBW1_mp0176	COG1509	lysine 2,3-aminomutase activity
XBW1_mp0179	COG3293	Transposase
XBW1_mp0181	COG2826	transposase and inactivated derivatives, IS30 family
XBW1_mp0195	COG3316	Transposase and inactivated derivatives
XBW1_p0006	COG3423	Transcriptional regulator