locus-tag	class	description
XBJ1_0003	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
XBJ1_0004	COG0187	DNA topoisomerase II activity
XBJ1_0008	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
XBJ1_0015	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
XBJ1_0019	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
XBJ1_0020	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
XBJ1_0021	COG0355	proton-transporting ATP synthase activity, rotational mechanism
XBJ1_0022	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
XBJ1_0023	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
XBJ1_0024	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
XBJ1_0025	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
XBJ1_0026	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
XBJ1_0028	COG0356	it plays a direct role in the translocation of protons across the membrane
XBJ1_0029	COG3312	ion transport
XBJ1_0030	COG0357	Ribosomal RNA small subunit methyltransferase G
XBJ1_0031	COG0445	tRNA wobble uridine modification
XBJ1_0032	COG0716	FMN binding
XBJ1_0033	COG1522	sequence-specific DNA binding
XBJ1_0034	COG2502	aspartate--ammonia ligase
XBJ1_0035	COG2425	protein containing a von Willebrand factor type A (vWA) domain
XBJ1_0036	COG0714	Associated with various cellular activities
XBJ1_0037	COG1869	D-ribose catabolic process
XBJ1_0038	COG1129	ABC transporter
XBJ1_0039	COG1172	Belongs to the binding-protein-dependent transport system permease family
XBJ1_0040	COG1879	ABC-type sugar transport system periplasmic component
XBJ1_0041	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XBJ1_0042	COG1609	Transcriptional regulator
XBJ1_0043	COG0477	Major facilitator Superfamily
XBJ1_0048	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
XBJ1_0049	COG3162	membrane
XBJ1_0050	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
XBJ1_0051	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
XBJ1_0052	COG0180	Tryptophanyl-tRNA synthetase
XBJ1_0053	COG0546	phosphoglycolate phosphatase activity
XBJ1_0054	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
XBJ1_0056	COG3266	domain, Protein
XBJ1_0057	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
XBJ1_0058	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
XBJ1_0060	COG4796	Type ii and iii secretion system protein
XBJ1_0065	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
XBJ1_0066	COG3335	DDE superfamily endonuclease
XBJ1_0067	COG0494	nUDIX hydrolase
XBJ1_0069	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
XBJ1_0070	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
XBJ1_0071	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
XBJ1_0072	COG1741	Belongs to the pirin family
XBJ1_0075	COG3335	DDE superfamily endonuclease
XBJ1_0079	COG1012	belongs to the aldehyde dehydrogenase family
XBJ1_0083	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
XBJ1_0084	COG3152	Membrane
XBJ1_0085	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XBJ1_0088	COG2081	HI0933 family
XBJ1_0089	COG0306	phosphate transporter
XBJ1_0090	COG0589	response to stress
XBJ1_0092	COG0742	ribosomal rna small subunit methyltransferase
XBJ1_0096	COG3335	DDE superfamily endonuclease
XBJ1_0097	COG0366	Alpha amylase catalytic
XBJ1_0098	COG1263	PTS System
XBJ1_0098	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
XBJ1_0100	COG1671	Belongs to the UPF0178 family
XBJ1_0108	COG1794	racemase activity, acting on amino acids and derivatives
XBJ1_0109	COG1181	Belongs to the D-alanine--D-alanine ligase family
XBJ1_0112	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
XBJ1_0116	COG3327	negative regulation of DNA-templated transcription, initiation
XBJ1_0117	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
XBJ1_0118	COG0183	Belongs to the thiolase family
XBJ1_0119	COG2050	protein possibly involved in aromatic compounds catabolism
XBJ1_0120	COG1250	3-hydroxyacyl-CoA dehydrogenase
XBJ1_0121	COG1024	Enoyl-CoA hydratase
XBJ1_0122	COG1024	Enoyl-CoA hydratase
XBJ1_0123	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
XBJ1_0124	COG2151	metal-sulfur cluster biosynthetic enzyme
XBJ1_0125	COG3396	Phenylacetate-CoA oxygenase
XBJ1_0126	COG3460	Phenylacetate-CoA oxygenase
XBJ1_0127	COG3396	Phenylacetate-CoA oxygenase
XBJ1_0128	COG1012	belongs to the aldehyde dehydrogenase family
XBJ1_0128	COG2030	dehydratase
XBJ1_0130	COG0626	cystathionine gamma-synthase activity
XBJ1_0133	COG1735	metal-dependent hydrolase with the TIM-barrel fold
XBJ1_0134	COG3457	Alanine racemase
XBJ1_0136	COG2188	Transcriptional regulator
XBJ1_0138	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
XBJ1_0140	COG1349	DNA-binding transcription factor activity
XBJ1_0141	COG0705	Rhomboid family
XBJ1_0142	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
XBJ1_0143	COG0316	Belongs to the HesB IscA family
XBJ1_0143	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
XBJ1_0144	COG1040	competence protein
XBJ1_0145	COG0596	Alpha beta hydrolase
XBJ1_0153	COG0693	protein deglycase activity
XBJ1_0158	COG2814	Major facilitator Superfamily
XBJ1_0162	COG2801	Transposase and inactivated derivatives
XBJ1_0165	COG1918	ferrous iron import across plasma membrane
XBJ1_0181	COG3501	Rhs element vgr protein
XBJ1_0184	COG2183	response to ionizing radiation
XBJ1_0185	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XBJ1_0186	COG0745	RESPONSE REGULATOR receiver
XBJ1_0188	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
XBJ1_0189	COG0573	inorganic phosphate transmembrane transporter activity
XBJ1_0190	COG0581	inorganic phosphate transmembrane transporter activity
XBJ1_0191	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
XBJ1_0192	COG0704	Plays a role in the regulation of phosphate uptake
XBJ1_0193	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
XBJ1_0194	COG0765	amino acid transport
XBJ1_0195	COG0765	amino acid transport
XBJ1_0205	COG2252	PERMEase
XBJ1_0207	COG3078	GTPase activator activity
XBJ1_0208	COG0635	Involved in the biosynthesis of porphyrin-containing compound
XBJ1_0209	COG2204	response regulator
XBJ1_0221	COG3335	DDE superfamily endonuclease
XBJ1_0225	COG1011	Hydrolase
XBJ1_0226	COG1490	D-aminoacyl-tRNA deacylase activity
XBJ1_0227	COG0456	acetyltransferase
XBJ1_0228	COG2982	Protein involved in outer membrane biogenesis
XBJ1_0229	COG2233	PERMEase
XBJ1_0230	COG0786	glutamate:sodium symporter activity
XBJ1_0231	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
XBJ1_0233	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
XBJ1_0234	COG1758	RNA polymerase activity
XBJ1_0235	COG0194	GDP metabolic process
XBJ1_0236	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
XBJ1_0237	COG2860	membrane
XBJ1_0238	COG0823	Involved in the tonB-independent uptake of proteins
XBJ1_0240	COG3335	DDE superfamily endonuclease
XBJ1_0241	COG3977	Valine--pyruvate aminotransferase
XBJ1_0242	COG2818	Glycosylase
XBJ1_0243	COG0752	glycyl-tRNA synthetase alpha subunit
XBJ1_0244	COG0751	glycine-tRNA ligase activity
XBJ1_0246	COG0747	negative chemotaxis
XBJ1_0247	COG0601	transmembrane transport
XBJ1_0248	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
XBJ1_0249	COG0444	Belongs to the ABC transporter superfamily
XBJ1_0250	COG4608	Belongs to the ABC transporter superfamily
XBJ1_0251	COG2200	EAL domain
XBJ1_0251	COG2199	diguanylate cyclase activity
XBJ1_0252	COG0612	Peptidase, M16
XBJ1_0254	COG0477	Major facilitator Superfamily
XBJ1_0256	COG1942	4-Oxalocrotonate Tautomerase
XBJ1_0257	COG1295	ribonuclease BN
XBJ1_0278	COG3501	Rhs element vgr protein
XBJ1_0281	COG3209	COG3209 Rhs family protein
XBJ1_0284	COG4372	Transposase
XBJ1_0287	COG4372	Transposase
XBJ1_0292	COG3209	COG3209 Rhs family protein
XBJ1_0316	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
XBJ1_0317	COG0802	atpase or kinase
XBJ1_0318	COG0860	N-Acetylmuramoyl-L-alanine amidase
XBJ1_0319	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
XBJ1_0320	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
XBJ1_0321	COG1923	regulation of RNA biosynthetic process
XBJ1_0322	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
XBJ1_0323	COG0330	HflC and HflK could
XBJ1_0324	COG0330	HflC and HflK could
XBJ1_0325	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
XBJ1_0326	COG1959	2 iron, 2 sulfur cluster binding
XBJ1_0327	COG0557	exoribonuclease II activity
XBJ1_0328	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
XBJ1_0329	COG0360	Binds together with S18 to 16S ribosomal RNA
XBJ1_0330	COG2965	DNA replication, synthesis of RNA primer
XBJ1_0333	COG0545	Peptidyl-prolyl cis-trans isomerase
XBJ1_0335	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
XBJ1_0338	COG1253	flavin adenine dinucleotide binding
XBJ1_0340	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
XBJ1_0341	COG0729	surface antigen
XBJ1_0342	COG2911	Protein conserved in bacteria
XBJ1_0343	COG2105	PFAM AIG2 family protein
XBJ1_0344	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
XBJ1_0346	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
XBJ1_0347	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
XBJ1_0349	COG0039	L-malate dehydrogenase activity
XBJ1_0350	COG3423	Transcriptional regulator
XBJ1_0353	COG0142	geranyltranstransferase activity
XBJ1_0355	COG0261	This protein binds to 23S rRNA in the presence of protein L20
XBJ1_0357	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
XBJ1_0358	COG2027	D-alanyl-D-alanine carboxypeptidase
XBJ1_0359	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XBJ1_0360	COG1534	Rna-binding protein
XBJ1_0361	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
XBJ1_0362	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
XBJ1_0363	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
XBJ1_0364	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
XBJ1_0365	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
XBJ1_0366	COG0779	Required for maturation of 30S ribosomal subunits
XBJ1_0367	COG0195	Participates in both transcription termination and antitermination
XBJ1_0368	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
XBJ1_0369	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
XBJ1_0370	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
XBJ1_0371	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
XBJ1_0374	COG0513	Belongs to the DEAD box helicase family
XBJ1_0376	COG3275	phosphorelay sensor kinase activity
XBJ1_0377	COG1388	LysM domain
XBJ1_0377	COG4932	domain protein
XBJ1_0377	COG2373	Large extracellular alpha-helical protein
XBJ1_0378	COG0582	viral genome integration into host DNA
XBJ1_0380	COG1028	Short-chain dehydrogenase reductase Sdr
XBJ1_0381	COG1028	Short-chain dehydrogenase reductase Sdr
XBJ1_0383	COG2814	Major facilitator Superfamily
XBJ1_0388	COG3153	acetyltransferase
XBJ1_0389	COG2827	Endonuclease containing a URI domain
XBJ1_0391	COG3787	Belongs to the UPF0306 family
XBJ1_0393	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
XBJ1_0396	COG5505	Protein of unknown function (DUF819)
XBJ1_0400	COG0540	Belongs to the ATCase OTCase family
XBJ1_0407	COG1028	Short-chain dehydrogenase reductase Sdr
XBJ1_0409	COG0512	Glutamine amidotransferase of anthranilate synthase
XBJ1_0414	COG4650	regulator
XBJ1_0417	COG1690	Belongs to the RtcB family
XBJ1_0418	COG3541	Predicted nucleotidyltransferase
XBJ1_0419	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
XBJ1_0420	COG1280	lysine exporter protein (LysE YggA)
XBJ1_0426	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XBJ1_0427	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
XBJ1_0428	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
XBJ1_0430	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
XBJ1_0431	COG1126	abc transporter atp-binding protein
XBJ1_0432	COG0765	amino acid transport
XBJ1_0435	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
XBJ1_0440	COG2337	Toxic component of a toxin-antitoxin (TA) module
XBJ1_0442	COG2336	PFAM SpoVT AbrB
XBJ1_0444	COG0525	valine-tRNA ligase activity
XBJ1_0445	COG2927	DNA polymerase III (CHI subunit)
XBJ1_0447	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
XBJ1_0448	COG0795	lipopolysaccharide-transporting ATPase activity
XBJ1_0449	COG0795	lipopolysaccharide-transporting ATPase activity
XBJ1_0450	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
XBJ1_0453	COG0582	viral genome integration into host DNA
XBJ1_0454	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
XBJ1_0459	COG3293	Transposase
XBJ1_0465	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
XBJ1_0468	COG1484	DNA-dependent DNA replication
XBJ1_0469	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
XBJ1_0469	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
XBJ1_0469	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
XBJ1_0472	COG1176	ABC-type spermidine putrescine transport system, permease component I
XBJ1_0473	COG1177	transmembrane transport
XBJ1_0474	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
XBJ1_0485	COG2873	o-acetylhomoserine
XBJ1_0492	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
XBJ1_0493	COG2363	Small membrane protein
XBJ1_0494	COG0583	DNA-binding transcription factor activity
XBJ1_0495	COG2252	PERMEase
XBJ1_0496	COG0025	NhaP-type Na H and K H
XBJ1_0497	COG0697	spore germination
XBJ1_0498	COG0583	DNA-binding transcription factor activity
XBJ1_0499	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
XBJ1_0502	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
XBJ1_0504	COG0586	Pfam SNARE associated Golgi protein
XBJ1_0505	COG1322	Protein conserved in bacteria
XBJ1_0506	COG2226	methyltransferase
XBJ1_0507	COG3165	ubiquinone biosynthetic process from chorismate
XBJ1_0508	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
XBJ1_0509	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
XBJ1_0510	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
XBJ1_0511	COG0805	protein transport
XBJ1_0514	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
XBJ1_0516	COG0183	Belongs to the thiolase family
XBJ1_0517	COG1024	Enoyl-CoA hydratase
XBJ1_0517	COG1250	3-hydroxyacyl-CoA dehydrogenase
XBJ1_0519	COG0006	proline dipeptidase activity
XBJ1_0520	COG1739	Uncharacterized protein family UPF0029
XBJ1_0522	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
XBJ1_0529	COG1914	H( )-stimulated, divalent metal cation uptake system
XBJ1_0530	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
XBJ1_0531	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
XBJ1_0532	COG4770	biotin carboxylase activity
XBJ1_0534	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
XBJ1_0536	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
XBJ1_0537	COG1053	succinate dehydrogenase
XBJ1_0539	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
XBJ1_0541	COG0584	glycerophosphoryl diester phosphodiesterase
XBJ1_0542	COG2271	Major facilitator Superfamily
XBJ1_0547	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
XBJ1_0548	COG0425	Belongs to the sulfur carrier protein TusA family
XBJ1_0550	COG3776	membrane
XBJ1_0551	COG0742	ribosomal rna small subunit methyltransferase
XBJ1_0553	COG0552	protein localization to endoplasmic reticulum
XBJ1_0554	COG2884	Cell division ATP-binding protein ftsE
XBJ1_0555	COG2177	Part of the ABC transporter FtsEX involved in
XBJ1_0557	COG1929	Belongs to the glycerate kinase type-1 family
XBJ1_0558	COG0456	acetyltransferase
XBJ1_0560	COG3501	Rhs element vgr protein
XBJ1_0576	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
XBJ1_0577	COG1611	Belongs to the LOG family
XBJ1_0578	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
XBJ1_0578	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
XBJ1_0582	COG3098	single-species biofilm formation
XBJ1_0587	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
XBJ1_0588	COG0024	Methionine aminopeptidase
XBJ1_0589	COG0052	Belongs to the universal ribosomal protein uS2 family
XBJ1_0590	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
XBJ1_0591	COG0528	UMP kinase activity
XBJ1_0592	COG0233	cytoplasmic translational termination
XBJ1_0593	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
XBJ1_0594	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
XBJ1_0595	COG0575	Belongs to the CDS family
XBJ1_0596	COG0750	zinc metalloprotease
XBJ1_0599	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XBJ1_0600	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
XBJ1_0601	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XBJ1_0602	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XBJ1_0603	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
XBJ1_0605	COG0825	malonyl-CoA metabolic process
XBJ1_0607	COG0037	tRNA processing
XBJ1_0608	COG4568	rho-dependent transcription termination
XBJ1_0609	COG3015	lipoprotein NlpE involved in copper resistance
XBJ1_0610	COG0442	prolyl-tRNA aminoacylation
XBJ1_0611	COG1720	tRNA m6t6A37 methyltransferase activity
XBJ1_0613	COG1464	Belongs to the NlpA lipoprotein family
XBJ1_0615	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
XBJ1_0624	COG2801	Transposase and inactivated derivatives
XBJ1_0626	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
XBJ1_0639	COG1304	FMN binding
XBJ1_0640	COG1620	l-lactate permease
XBJ1_0645	COG3545	Serine hydrolase
XBJ1_0656	COG5301	cellulose 1,4-beta-cellobiosidase activity
XBJ1_0656	COG5301	cellulose 1,4-beta-cellobiosidase activity
XBJ1_0679	COG4695	Portal protein
XBJ1_0697	COG0484	heat shock protein binding
XBJ1_0705	COG3561	AntA/AntB antirepressor
XBJ1_0711	COG0582	viral genome integration into host DNA
XBJ1_0716	COG1278	Cold shock
XBJ1_0718	COG3397	chitin binding
XBJ1_0719	COG0346	lactoylglutathione lyase activity
XBJ1_0726	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
XBJ1_0727	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
XBJ1_0728	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
XBJ1_0729	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
XBJ1_0731	COG2205	protein histidine kinase activity
XBJ1_0731	COG0784	Response regulator, receiver
XBJ1_0732	COG2197	response regulator
XBJ1_0733	COG0642	Histidine kinase
XBJ1_0733	COG2198	Histidine kinase
XBJ1_0734	COG0814	amino acid
XBJ1_0737	COG1441	menaquinone biosynthetic process
XBJ1_0738	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
XBJ1_0739	COG0596	Alpha beta hydrolase
XBJ1_0740	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
XBJ1_0742	COG3188	usher protein
XBJ1_0743	COG3121	Chaperone
XBJ1_0753	COG3335	DDE superfamily endonuclease
XBJ1_0758	COG3335	DDE superfamily endonuclease
XBJ1_0760	COG0582	viral genome integration into host DNA
XBJ1_0761	COG2920	part of a sulfur-relay system
XBJ1_0762	COG1254	Belongs to the acylphosphatase family
XBJ1_0764	COG3785	DNA binding
XBJ1_0765	COG1832	CoA-binding protein
XBJ1_0766	COG0210	DNA helicase
XBJ1_0767	COG1289	transmembrane transporter activity
XBJ1_0771	COG4372	Transposase
XBJ1_0776	COG3070	regulator of competence-specific genes
XBJ1_0779	COG3120	sequence-specific DNA binding
XBJ1_0780	COG1067	ATP-dependent peptidase activity
XBJ1_0782	COG3130	regulation of translation
XBJ1_0783	COG3009	Protein conserved in bacteria
XBJ1_0784	COG3008	intermembrane lipid transfer
XBJ1_0784	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
XBJ1_0785	COG2995	paraquat-inducible protein a
XBJ1_0786	COG0488	(ABC) transporter
XBJ1_0787	COG0116	Belongs to the methyltransferase superfamily
XBJ1_0787	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
XBJ1_0788	COG0633	Ferredoxin
XBJ1_0788	COG3217	Mosc domain protein beta barrel domain protein
XBJ1_0790	COG0167	dihydroorotate dehydrogenase activity
XBJ1_0791	COG0308	aminopeptidase N
XBJ1_0792	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
XBJ1_0793	COG0017	Asparaginyl-tRNA synthetase
XBJ1_0794	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
XBJ1_0796	COG1448	Aminotransferase
XBJ1_0797	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XBJ1_0798	COG3108	Peptidase M15
XBJ1_0799	COG2989	Protein conserved in bacteria
XBJ1_0800	COG3700	Belongs to the class B bacterial acid phosphatase family
XBJ1_0802	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
XBJ1_0803	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
XBJ1_0804	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
XBJ1_0805	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
XBJ1_0806	COG1434	Gram-negative-bacterium-type cell wall biogenesis
XBJ1_0807	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
XBJ1_0808	COG2835	tetraacyldisaccharide 4'-kinase activity
XBJ1_0809	COG1663	tetraacyldisaccharide 4'-kinase activity
XBJ1_0810	COG1132	(ABC) transporter
XBJ1_0811	COG2333	competence protein COMEC
XBJ1_0811	COG0658	competence protein
XBJ1_0814	COG0539	negative regulation of cytoplasmic translation
XBJ1_0815	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
XBJ1_0816	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
XBJ1_0817	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
XBJ1_0818	COG0252	asparaginase activity
XBJ1_0819	COG1944	ATP diphosphatase activity
XBJ1_0820	COG2116	formate transmembrane transporter activity
XBJ1_0821	COG1882	Formate acetyltransferase
XBJ1_0822	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
XBJ1_0827	COG3335	DDE superfamily endonuclease
XBJ1_0828	COG0540	Belongs to the ATCase OTCase family
XBJ1_0829	COG0540	Belongs to the ATCase OTCase family
XBJ1_0833	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
XBJ1_0835	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
XBJ1_0836	COG1492	cobalamin metabolic process
XBJ1_0846	COG2875	Belongs to the precorrin methyltransferase family
XBJ1_0848	COG2241	protein methyltransferase activity
XBJ1_0849	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
XBJ1_0851	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
XBJ1_0853	COG1648	precorrin-2 dehydrogenase activity
XBJ1_0853	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
XBJ1_0854	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XBJ1_0856	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
XBJ1_0857	COG0346	lactoylglutathione lyase activity
XBJ1_0864	COG1662	PFAM IS1 transposase
XBJ1_0865	COG1846	Transcriptional regulator
XBJ1_0866	COG0179	Fumarylacetoacetate (FAA) hydrolase
XBJ1_0868	COG1012	belongs to the aldehyde dehydrogenase family
XBJ1_0869	COG3384	dioxygenase
XBJ1_0872	COG3971	2-oxopent-4-enoate hydratase activity
XBJ1_0876	COG3316	Transposase and inactivated derivatives
XBJ1_0878	COG0501	Belongs to the peptidase M48B family
XBJ1_0879	COG0733	neurotransmitter:sodium symporter activity
XBJ1_0886	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
XBJ1_0887	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
XBJ1_0888	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
XBJ1_0889	COG3107	peptidoglycan biosynthetic process
XBJ1_0889	COG1674	ftsk spoiiie
XBJ1_0890	COG1522	sequence-specific DNA binding
XBJ1_0892	COG0492	ferredoxin-NADP+ reductase activity
XBJ1_0894	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
XBJ1_0895	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
XBJ1_0897	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
XBJ1_0898	COG0542	response to heat
XBJ1_0899	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
XBJ1_0900	COG1278	Cold shock
XBJ1_0901	COG2431	L-lysine efflux transmembrane transporter activity
XBJ1_0902	COG1126	abc transporter atp-binding protein
XBJ1_0903	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
XBJ1_0904	COG4215	(ABC) transporter
XBJ1_0905	COG4160	amino acid transport
XBJ1_0906	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
XBJ1_0909	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
XBJ1_0910	COG0671	phosphoesterase, PA-phosphatase related
XBJ1_0911	COG0814	amino acid
XBJ1_0912	COG1686	Belongs to the peptidase S11 family
XBJ1_0913	COG0625	glutathione transferase activity
XBJ1_0914	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XBJ1_0916	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
XBJ1_0917	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
XBJ1_0917	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XBJ1_0918	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
XBJ1_0918	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XBJ1_0919	COG0131	Imidazoleglycerol-phosphate dehydratase
XBJ1_0919	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
XBJ1_0920	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
XBJ1_0921	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
XBJ1_0922	COG0107	imidazoleglycerol-phosphate synthase activity
XBJ1_0923	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
XBJ1_0923	COG0140	phosphoribosyl-ATP diphosphatase activity
XBJ1_0925	COG1454	alcohol dehydrogenase
XBJ1_0928	COG1253	flavin adenine dinucleotide binding
XBJ1_0929	COG5301	cellulose 1,4-beta-cellobiosidase activity
XBJ1_0931	COG2982	Protein involved in outer membrane biogenesis
XBJ1_0932	COG0717	Belongs to the dCTP deaminase family
XBJ1_0933	COG0572	uridine kinase
XBJ1_0935	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
XBJ1_0935	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
XBJ1_0936	COG1380	Effector of murein hydrolase LrgA
XBJ1_0938	COG1346	cytolysis
XBJ1_0939	COG0295	cytidine deaminase activity
XBJ1_0940	COG0281	malic enzyme
XBJ1_0942	COG2949	membrane
XBJ1_0943	COG2311	Membrane
XBJ1_0944	COG0302	gtp cyclohydrolase
XBJ1_0946	COG0477	Major facilitator Superfamily
XBJ1_0948	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
XBJ1_0953	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
XBJ1_0954	COG0488	(ABC) transporter
XBJ1_0960	COG5006	permease, DMT superfamily
XBJ1_0963	COG2824	Alkylphosphonate utilization operon protein PhnA
XBJ1_0966	COG2897	thiosulfate sulfurtransferase activity
XBJ1_0967	COG2261	transglycosylase associated protein
XBJ1_0968	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
XBJ1_0969	COG0513	Belongs to the DEAD box helicase family
XBJ1_0970	COG1309	transcriptional regulator
XBJ1_0972	COG1131	(ABC) transporter
XBJ1_0973	COG0842	Transport permease protein
XBJ1_0974	COG0842	Transport permease protein
XBJ1_0975	COG0670	Belongs to the BI1 family
XBJ1_0976	COG0314	molybdopterin synthase activity
XBJ1_0977	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
XBJ1_0979	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
XBJ1_0980	COG0391	Required for morphogenesis under gluconeogenic growth conditions
XBJ1_0981	COG0556	nucleotide-excision repair
XBJ1_0982	COG4974	Belongs to the 'phage' integrase family
XBJ1_0996	COG4695	Portal protein
XBJ1_1023	COG2226	methyltransferase
XBJ1_1024	COG0156	8-amino-7-oxononanoate synthase activity
XBJ1_1025	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
XBJ1_1026	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
XBJ1_1028	COG2706	6-phosphogluconolactonase activity
XBJ1_1029	COG0561	phosphatase activity
XBJ1_1030	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
XBJ1_1031	COG4149	molybdate abc transporter
XBJ1_1032	COG0725	ABC transporter, periplasmic molybdate-binding protein
XBJ1_1035	COG3585	molybdate ion transport
XBJ1_1035	COG2005	Transcriptional regulator
XBJ1_1036	COG1119	ATPase activity
XBJ1_1038	COG0588	phosphoglycerate mutase activity
XBJ1_1039	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
XBJ1_1042	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
XBJ1_1043	COG2885	chlorophyll binding
XBJ1_1044	COG0823	Involved in the tonB-independent uptake of proteins
XBJ1_1045	COG3064	Membrane
XBJ1_1046	COG0848	biopolymer transport protein
XBJ1_1047	COG0811	peptide transport
XBJ1_1048	COG0824	Thioesterase
XBJ1_1049	COG3790	cyd operon protein YbgE
XBJ1_1051	COG4890	Cyd operon protein YbgT
XBJ1_1052	COG1294	oxidase, subunit
XBJ1_1053	COG1271	oxidase subunit
XBJ1_1054	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
XBJ1_1055	COG0045	succinate-CoA ligase (ADP-forming) activity
XBJ1_1056	COG0508	dehydrogenase complex catalyzes the overall conversion of
XBJ1_1057	COG0567	Dehydrogenase, E1 component
XBJ1_1060	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
XBJ1_1061	COG2009	succinate dehydrogenase
XBJ1_1062	COG0372	Belongs to the citrate synthase family
XBJ1_1064	COG2814	Major facilitator Superfamily
XBJ1_1065	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
XBJ1_1067	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
XBJ1_1068	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
XBJ1_1069	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
XBJ1_1070	COG2205	protein histidine kinase activity
XBJ1_1071	COG0745	RESPONSE REGULATOR receiver
XBJ1_1074	COG0033	Phosphoglucomutase
XBJ1_1075	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
XBJ1_1076	COG0596	Alpha beta hydrolase
XBJ1_1085	COG3210	domain, Protein
XBJ1_1087	COG3501	Rhs element vgr protein
XBJ1_1089	COG1073	alpha beta
XBJ1_1089	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
XBJ1_1089	COG3064	Membrane
XBJ1_1090	COG2994	toxin metabolic process
XBJ1_1095	COG0662	Cupin 2, conserved barrel domain protein
XBJ1_1095	COG2207	Transcriptional regulator
XBJ1_1096	COG0582	viral genome integration into host DNA
XBJ1_1098	COG1388	LysM domain
XBJ1_1098	COG1470	cell adhesion involved in biofilm formation
XBJ1_1099	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XBJ1_1103	COG0582	viral genome integration into host DNA
XBJ1_1104	COG4932	domain protein
XBJ1_1104	COG2373	Large extracellular alpha-helical protein
XBJ1_1104	COG1388	LysM domain
XBJ1_1107	COG0716	FMN binding
XBJ1_1108	COG0735	belongs to the Fur family
XBJ1_1110	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
XBJ1_1111	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
XBJ1_1112	COG2223	nitrite transmembrane transporter activity
XBJ1_1113	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
XBJ1_1114	COG3335	DDE superfamily endonuclease
XBJ1_1117	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
XBJ1_1118	COG2814	Major facilitator Superfamily
XBJ1_1119	COG3962	Belongs to the TPP enzyme family
XBJ1_1124	COG1309	transcriptional regulator
XBJ1_1127	COG1222	aaa ATPase
XBJ1_1144	COG1262	PFAM Formylglycine-generating sulfatase enzyme
XBJ1_1152	COG2304	oxidoreductase activity
XBJ1_1157	COG2501	S4 domain
XBJ1_1158	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
XBJ1_1160	COG0582	viral genome integration into host DNA
XBJ1_1190	COG0305	Participates in initiation and elongation during chromosome replication
XBJ1_1196	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
XBJ1_1205	COG3646	Phage regulatory protein
XBJ1_1208	COG3335	DDE superfamily endonuclease
XBJ1_1210	COG5484	DNA packaging
XBJ1_1210	COG3728	DNA packaging
XBJ1_1250	COG1484	DNA-dependent DNA replication
XBJ1_1251	COG0305	Participates in initiation and elongation during chromosome replication
XBJ1_1254	COG2189	Belongs to the N(4) N(6)-methyltransferase family
XBJ1_1258	COG3772	lysozyme
XBJ1_1264	COG4626	Terminase
XBJ1_1264	COG1802	Transcriptional regulator
XBJ1_1266	COG4695	Portal protein
XBJ1_1290	COG3657	addiction module killer protein
XBJ1_1291	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
XBJ1_1296	COG3209	COG3209 Rhs family protein
XBJ1_1298	COG3209	COG3209 Rhs family protein
XBJ1_1301	COG3501	Rhs element vgr protein
XBJ1_1302	COG1396	sequence-specific DNA binding
XBJ1_1305	COG3209	COG3209 Rhs family protein
XBJ1_1308	COG3501	Rhs element vgr protein
XBJ1_1315	COG0582	viral genome integration into host DNA
XBJ1_1316	COG0582	viral genome integration into host DNA
XBJ1_1345	COG0372	Belongs to the citrate synthase family
XBJ1_1350	COG3038	cytochrome b561
XBJ1_1351	COG2353	YceI-like domain
XBJ1_1358	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
XBJ1_1361	COG2841	Protein conserved in bacteria
XBJ1_1372	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
XBJ1_1377	COG2801	Transposase and inactivated derivatives
XBJ1_1378	COG2801	Transposase and inactivated derivatives
XBJ1_1387	COG3772	lysozyme
XBJ1_1402	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
XBJ1_1403	COG1028	Short-chain dehydrogenase reductase Sdr
XBJ1_1412	COG0732	type I restriction modification DNA specificity domain
XBJ1_1413	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
XBJ1_1415	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
XBJ1_1421	COG0464	growth
XBJ1_1424	COG3293	Transposase
XBJ1_1432	COG3335	DDE superfamily endonuclease
XBJ1_1435	COG1535	isochorismatase
XBJ1_1435	COG3433	isochorismatase activity
XBJ1_1436	COG1021	2,3-dihydroxybenzoate-AMP ligase
XBJ1_1437	COG1169	isochorismate synthase
XBJ1_1438	COG4774	siderophore transport
XBJ1_1439	COG2382	esterase
XBJ1_1440	COG3251	PFAM MbtH domain protein
XBJ1_1442	COG1120	ATPase activity
XBJ1_1443	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
XBJ1_1444	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
XBJ1_1446	COG4592	Periplasmic binding protein
XBJ1_1449	COG0010	Belongs to the arginase family
XBJ1_1451	COG0583	DNA-binding transcription factor activity
XBJ1_1452	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
XBJ1_1453	COG0066	3-isopropylmalate dehydratase activity
XBJ1_1455	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
XBJ1_1456	COG4232	protein-disulfide reductase activity
XBJ1_1457	COG1309	transcriptional regulator
XBJ1_1459	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
XBJ1_1484	COG0515	serine threonine protein kinase
XBJ1_1487	COG2204	response regulator
XBJ1_1490	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
XBJ1_1501	COG3501	Rhs element vgr protein
XBJ1_1516	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
XBJ1_1540	COG3423	Transcriptional regulator
XBJ1_1548	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
XBJ1_1554	COG0305	Participates in initiation and elongation during chromosome replication
XBJ1_1557	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
XBJ1_1559	COG4372	Transposase
XBJ1_1575	COG4372	Transposase
XBJ1_1576	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
XBJ1_1586	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XBJ1_1587	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
XBJ1_1588	COG4181	ATPase activity
XBJ1_1589	COG2755	lipolytic protein G-D-S-L family
XBJ1_1590	COG0300	oxidoreductase activity
XBJ1_1591	COG3118	belongs to the thioredoxin family
XBJ1_1592	COG0330	HflC and HflK could
XBJ1_1594	COG0789	Transcriptional regulator
XBJ1_1595	COG2217	Heavy metal translocating P-type atpase
XBJ1_1596	COG3735	TraB family
XBJ1_1597	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
XBJ1_1598	COG0737	Belongs to the 5'-nucleotidase family
XBJ1_1600	COG2223	nitrite transmembrane transporter activity
XBJ1_1601	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
XBJ1_1601	COG4651	solute:proton antiporter activity
XBJ1_1602	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XBJ1_1603	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
XBJ1_1604	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
XBJ1_1605	COG0563	adenylate kinase activity
XBJ1_1606	COG0326	Molecular chaperone. Has ATPase activity
XBJ1_1609	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
XBJ1_1610	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
XBJ1_1611	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
XBJ1_1612	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
XBJ1_1615	COG1196	nuclear chromosome segregation
XBJ1_1615	COG3264	Mechanosensitive ion channel
XBJ1_1616	COG1309	transcriptional regulator
XBJ1_1617	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XBJ1_1618	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XBJ1_1622	COG0004	ammonium transporteR
XBJ1_1623	COG0347	Belongs to the P(II) protein family
XBJ1_1625	COG1132	(ABC) transporter
XBJ1_1626	COG1132	(ABC) transporter
XBJ1_1628	COG1522	sequence-specific DNA binding
XBJ1_1629	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
XBJ1_1630	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
XBJ1_1631	COG0824	Thioesterase
XBJ1_1632	COG1555	photosystem II stabilization
XBJ1_1633	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
XBJ1_1635	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
XBJ1_1636	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
XBJ1_1637	COG0740	serine-type endopeptidase activity
XBJ1_1638	COG0544	peptidyl-prolyl cis-trans isomerase activity
XBJ1_1640	COG0271	Belongs to the BolA IbaG family
XBJ1_1641	COG3056	Lipoprotein
XBJ1_1642	COG2223	nitrite transmembrane transporter activity
XBJ1_1646	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
XBJ1_1647	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
XBJ1_1648	COG1845	cytochrome c oxidase, subunit III
XBJ1_1649	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
XBJ1_1650	COG0109	protoheme IX farnesyltransferase activity
XBJ1_1651	COG2814	Major facilitator Superfamily
XBJ1_1653	COG1666	GTP binding
XBJ1_1654	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
XBJ1_1655	COG0693	protein deglycase activity
XBJ1_1656	COG0301	tRNA thio-modification
XBJ1_1656	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
XBJ1_1658	COG0142	geranyltranstransferase activity
XBJ1_1659	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
XBJ1_1660	COG1509	lysine 2,3-aminomutase activity
XBJ1_1667	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
XBJ1_1668	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
XBJ1_1669	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
XBJ1_1670	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
XBJ1_1671	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
XBJ1_1672	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
XBJ1_1672	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
XBJ1_1673	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
XBJ1_1676	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
XBJ1_1678	COG1862	Preprotein translocase
XBJ1_1680	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
XBJ1_1681	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
XBJ1_1683	COG0450	alkyl hydroperoxide reductase
XBJ1_1685	COG1114	Component of the transport system for branched-chain amino acids
XBJ1_1687	COG5002	protein histidine kinase activity
XBJ1_1688	COG0745	RESPONSE REGULATOR receiver
XBJ1_1689	COG0420	3'-5' exonuclease activity
XBJ1_1690	COG0419	ATPase involved in DNA repair
XBJ1_1696	COG0737	Belongs to the 5'-nucleotidase family
XBJ1_1698	COG0737	Belongs to the 5'-nucleotidase family
XBJ1_1702	COG1940	carbohydrate kinase activity
XBJ1_1703	COG2974	May be involved in recombination
XBJ1_1704	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
XBJ1_1706	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
XBJ1_1713	COG0848	biopolymer transport protein
XBJ1_1714	COG0811	peptide transport
XBJ1_1716	COG0626	cystathionine gamma-synthase activity
XBJ1_1717	COG0586	Pfam SNARE associated Golgi protein
XBJ1_1718	COG0656	L-ascorbic acid biosynthetic process
XBJ1_1720	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
XBJ1_1721	COG0505	Belongs to the CarA family
XBJ1_1722	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
XBJ1_1723	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
XBJ1_1724	COG1047	Peptidyl-prolyl cis-trans
XBJ1_1725	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
XBJ1_1726	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
XBJ1_1727	COG0196	riboflavin kinase activity
XBJ1_1729	COG0268	Binds directly to 16S ribosomal RNA
XBJ1_1730	COG0583	DNA-binding transcription factor activity
XBJ1_1731	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
XBJ1_1735	COG2814	Major facilitator Superfamily
XBJ1_1736	COG0367	asparagine synthase
XBJ1_1737	COG3335	DDE superfamily endonuclease
XBJ1_1738	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
XBJ1_1739	COG0740	serine-type endopeptidase activity
XBJ1_1741	COG0484	heat shock protein binding
XBJ1_1742	COG0443	Heat shock 70 kDa protein
XBJ1_1743	COG1584	GPR1 FUN34 yaaH family protein
XBJ1_1744	COG0477	Major facilitator Superfamily
XBJ1_1749	COG1960	acyl-CoA dehydrogenase activity
XBJ1_1756	COG0367	asparagine synthase
XBJ1_1757	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
XBJ1_1773	COG2862	Uncharacterized protein family, UPF0114
XBJ1_1777	COG1358	cellular component organization or biogenesis
XBJ1_1786	COG0582	viral genome integration into host DNA
XBJ1_1790	COG1662	PFAM IS1 transposase
XBJ1_1795	COG0417	DNA replication proofreading
XBJ1_1796	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
XBJ1_1797	COG0564	pseudouridine synthase activity
XBJ1_1798	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
XBJ1_1799	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
XBJ1_1800	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
XBJ1_1801	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
XBJ1_1802	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
XBJ1_1803	COG2967	ApaG domain
XBJ1_1804	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
XBJ1_1807	COG2132	Multicopper oxidase
XBJ1_1808	COG0204	Acyl-transferase
XBJ1_1809	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
XBJ1_1810	COG0187	DNA topoisomerase II activity
XBJ1_1811	COG3150	esterase
XBJ1_1812	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
XBJ1_1813	COG0494	nUDIX hydrolase
XBJ1_1814	COG1538	Outer membrane efflux protein
XBJ1_1815	COG5463	Belongs to the UPF0441 family
XBJ1_1816	COG0754	glutathionylspermidine amidase activity
XBJ1_1817	COG3384	dioxygenase
XBJ1_1819	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
XBJ1_1822	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
XBJ1_1822	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
XBJ1_1823	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
XBJ1_1824	COG3025	triphosphatase activity
XBJ1_1826	COG4991	sh3 domain protein
XBJ1_1827	COG0617	tRNA 3'-terminal CCA addition
XBJ1_1828	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
XBJ1_1829	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
XBJ1_1830	COG2867	negative regulation of translational initiation
XBJ1_1830	COG2226	methyltransferase
XBJ1_1831	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
XBJ1_1833	COG0358	DNA primase activity
XBJ1_1834	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
XBJ1_1840	COG2003	Belongs to the UPF0758 family
XBJ1_1845	COG2378	regulation of single-species biofilm formation
XBJ1_1847	COG3596	GTP binding
XBJ1_1874	COG3335	DDE superfamily endonuclease
XBJ1_1878	COG3677	Transposase
XBJ1_1880	COG3385	transposase activity
XBJ1_1881	COG1662	PFAM IS1 transposase
XBJ1_1885	COG5433	transposase activity
XBJ1_1895	COG1560	Kdo2-lipid A biosynthetic process
XBJ1_1900	COG0418	dihydroorotase activity
XBJ1_1908	COG1278	Cold shock
XBJ1_1920	COG1360	Flagellar Motor Protein
XBJ1_1921	COG0643	Histidine kinase
XBJ1_1921	COG2198	Histidine kinase
XBJ1_1922	COG0835	chemotaxis
XBJ1_1923	COG0840	transmembrane signaling receptor activity
XBJ1_1924	COG0840	transmembrane signaling receptor activity
XBJ1_1925	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
XBJ1_1926	COG2201	protein-glutamate methylesterase activity
XBJ1_1927	COG0745	RESPONSE REGULATOR receiver
XBJ1_1928	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
XBJ1_1937	COG1115	amino acid carrier protein
XBJ1_1938	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
XBJ1_1944	COG3121	Chaperone
XBJ1_1946	COG3539	Fimbrial protein
XBJ1_1950	COG1815	bacterial-type flagellum-dependent cell motility
XBJ1_1951	COG1558	bacterial-type flagellum-dependent cell motility
XBJ1_1952	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
XBJ1_1953	COG1749	Flagellar hook protein flgE
XBJ1_1955	COG4786	Flagellar basal body rod
XBJ1_1957	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
XBJ1_1959	COG1706	bacterial-type flagellum-dependent cell motility
XBJ1_1961	COG1256	bacterial-type flagellum assembly
XBJ1_1962	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
XBJ1_1975	COG2831	hemolysin activation secretion protein
XBJ1_1978	COG5433	transposase activity
XBJ1_1980	COG3547	Transposase (IS116 IS110 IS902 family)
XBJ1_1988	COG1403	HNH endonuclease
XBJ1_1996	COG1191	sigma factor activity
XBJ1_1998	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
XBJ1_1998	COG0506	proline dehydrogenase activity
XBJ1_1998	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
XBJ1_1999	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
XBJ1_2017	COG3335	DDE superfamily endonuclease
XBJ1_2045	COG0740	serine-type endopeptidase activity
XBJ1_2067	COG2239	Acts as a magnesium transporter
XBJ1_2068	COG0248	Ppx GppA phosphatase
XBJ1_2069	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
XBJ1_2070	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
XBJ1_2072	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
XBJ1_2073	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
XBJ1_2079	COG1403	HNH endonuclease
XBJ1_2094	COG3316	Transposase and inactivated derivatives
XBJ1_2114	COG3501	Rhs element vgr protein
XBJ1_2120	COG3104	oligopeptide transport
XBJ1_2121	COG2271	Major facilitator Superfamily
XBJ1_2122	COG3851	Histidine kinase
XBJ1_2123	COG3850	Histidine kinase
XBJ1_2125	COG1294	oxidase, subunit
XBJ1_2126	COG1271	oxidase subunit
XBJ1_2127	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
XBJ1_2133	COG1028	Short-chain dehydrogenase reductase Sdr
XBJ1_2134	COG2267	carboxylic ester hydrolase activity
XBJ1_2140	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
XBJ1_2145	COG3335	DDE superfamily endonuclease
XBJ1_2146	COG2267	carboxylic ester hydrolase activity
XBJ1_2149	COG1388	LysM domain
XBJ1_2149	COG2373	Large extracellular alpha-helical protein
XBJ1_2149	COG4932	domain protein
XBJ1_2155	COG2249	NAD(P)H dehydrogenase (quinone) activity
XBJ1_2156	COG2207	Transcriptional regulator
XBJ1_2160	COG2226	methyltransferase
XBJ1_2161	COG1619	proteins homologs of microcin C7 resistance protein MccF
XBJ1_2162	COG0813	purine-nucleoside phosphorylase activity
XBJ1_2165	COG0495	leucyl-tRNA aminoacylation
XBJ1_2166	COG0442	prolyl-tRNA aminoacylation
XBJ1_2175	COG2175	clavaminate synthase activity
XBJ1_2176	COG0667	Aldo Keto reductase
XBJ1_2179	COG4555	ABC transporter
XBJ1_2187	COG0431	NADPH-dependent FMN reductase
XBJ1_2194	COG0012	GTP binding
XBJ1_2195	COG0193	aminoacyl-tRNA hydrolase activity
XBJ1_2198	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
XBJ1_2199	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
XBJ1_2200	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
XBJ1_2201	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
XBJ1_2202	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
XBJ1_2203	COG2890	protein-(glutamine-N5) methyltransferase activity
XBJ1_2204	COG2912	Transglutaminase-like superfamily
XBJ1_2205	COG2877	3-deoxy-8-phosphooctulonate synthase activity
XBJ1_2206	COG0659	secondary active sulfate transmembrane transporter activity
XBJ1_2208	COG2453	phosphatase
XBJ1_2208	COG0671	phosphoesterase, PA-phosphatase related
XBJ1_2209	COG2267	carboxylic ester hydrolase activity
XBJ1_2210	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
XBJ1_2211	COG2378	regulation of single-species biofilm formation
XBJ1_2213	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
XBJ1_2214	COG3381	protein complex oligomerization
XBJ1_2216	COG0477	Major facilitator Superfamily
XBJ1_2218	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
XBJ1_2222	COG0018	arginyl-trna synthetase
XBJ1_2223	COG3102	Protein conserved in bacteria
XBJ1_2224	COG1187	pseudouridine synthase activity
XBJ1_2226	COG1108	ABC-type Mn2 Zn2 transport systems permease components
XBJ1_2227	COG1121	(ABC) transporter
XBJ1_2228	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
XBJ1_2229	COG0739	heme binding
XBJ1_2230	COG1560	Kdo2-lipid A biosynthetic process
XBJ1_2231	COG0469	pyruvate kinase activity
XBJ1_2232	COG1737	Transcriptional regulator
XBJ1_2233	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
XBJ1_2234	COG2076	Multidrug Resistance protein
XBJ1_2235	COG2076	Multidrug Resistance protein
XBJ1_2236	COG0251	oxidation-reduction process
XBJ1_2237	COG1199	ATP-dependent helicase activity
XBJ1_2239	COG3065	identical protein binding
XBJ1_2242	COG0318	PFAM AMP-dependent synthetase and ligase
XBJ1_2247	COG1982	Orn Lys Arg decarboxylase major
XBJ1_2248	COG0531	amino acid
XBJ1_2249	COG2313	pseudouridylate synthase activity
XBJ1_2250	COG2313	pseudouridylate synthase activity
XBJ1_2252	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
XBJ1_2253	COG0589	response to stress
XBJ1_2254	COG0589	response to stress
XBJ1_2256	COG2356	endonuclease I
XBJ1_2257	COG3142	Participates in the control of copper homeostasis
XBJ1_2259	COG0500	methyltransferase
XBJ1_2260	COG2226	methyltransferase
XBJ1_2261	COG3788	relative of glutathione S-transferase, MAPEG superfamily
XBJ1_2262	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
XBJ1_2263	COG0494	nUDIX hydrolase
XBJ1_2264	COG0217	transcriptional regulatory protein
XBJ1_2265	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
XBJ1_2266	COG0632	four-way junction helicase activity
XBJ1_2267	COG2255	four-way junction helicase activity
XBJ1_2270	COG3047	cAMP biosynthetic process
XBJ1_2272	COG2823	Periplasmic or secreted lipoprotein
XBJ1_2274	COG0159	tryptophan synthase activity
XBJ1_2275	COG0133	tryptophan synthase activity
XBJ1_2277	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
XBJ1_2281	COG0009	L-threonylcarbamoyladenylate synthase
XBJ1_2283	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
XBJ1_2284	COG1028	Short-chain dehydrogenase reductase Sdr
XBJ1_2285	COG0616	signal peptide processing
XBJ1_2289	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
XBJ1_2295	COG1943	Transposase
XBJ1_2297	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
XBJ1_2298	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
XBJ1_2299	COG0284	orotidine-5'-phosphate decarboxylase activity
XBJ1_2300	COG0023	Translation Initiation Factor
XBJ1_2302	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
XBJ1_2303	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
XBJ1_2305	COG4659	FMN binding
XBJ1_2309	COG4657	Part of a membrane complex involved in electron transport
XBJ1_2311	COG0673	inositol 2-dehydrogenase activity
XBJ1_2312	COG0385	Bile acid
XBJ1_2313	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
XBJ1_2314	COG5339	Protein conserved in bacteria
XBJ1_2315	COG1482	cell wall glycoprotein biosynthetic process
XBJ1_2316	COG0114	fumarate hydratase activity
XBJ1_2319	COG2814	Major facilitator Superfamily
XBJ1_2320	COG0583	DNA-binding transcription factor activity
XBJ1_2321	COG1940	carbohydrate kinase activity
XBJ1_2322	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
XBJ1_2327	COG4221	oxidoreductase activity
XBJ1_2339	COG1846	Transcriptional regulator
XBJ1_2340	COG0697	spore germination
XBJ1_2342	COG2226	methyltransferase
XBJ1_2347	COG2814	Major facilitator Superfamily
XBJ1_2350	COG3335	DDE superfamily endonuclease
XBJ1_2353	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XBJ1_2354	COG0589	response to stress
XBJ1_2355	COG4974	Belongs to the 'phage' integrase family
XBJ1_2356	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
XBJ1_2357	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
XBJ1_2360	COG0531	amino acid
XBJ1_2364	COG3121	Chaperone
XBJ1_2368	COG1643	Atp-dependent helicase
XBJ1_2369	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
XBJ1_2370	COG3784	Protein of unknown function (DUF1318)
XBJ1_2372	COG2911	Protein conserved in bacteria
XBJ1_2373	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
XBJ1_2378	COG2983	Belongs to the UPF0260 family
XBJ1_2379	COG0179	Fumarylacetoacetate (FAA) hydrolase
XBJ1_2380	COG2951	lytic endotransglycosylase activity
XBJ1_2382	COG3100	YcgL domain-containing protein
XBJ1_2383	COG0850	regulation of cytokinetic process
XBJ1_2384	COG2894	cell division
XBJ1_2385	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
XBJ1_2386	COG3335	DDE superfamily endonuclease
XBJ1_2387	COG3316	Transposase and inactivated derivatives
XBJ1_2392	COG2814	Major facilitator Superfamily
XBJ1_2393	COG2084	Dehydrogenase
XBJ1_2398	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
XBJ1_2402	COG0803	Belongs to the bacterial solute-binding protein 9 family
XBJ1_2403	COG1121	(ABC) transporter
XBJ1_2404	COG1108	ABC-type Mn2 Zn2 transport systems permease components
XBJ1_2405	COG1108	ABC-type Mn2 Zn2 transport systems permease components
XBJ1_2410	COG1073	alpha beta
XBJ1_2410	COG3064	Membrane
XBJ1_2410	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
XBJ1_2412	COG2917	probably involved in intracellular septation
XBJ1_2413	COG1607	acyl-coa hydrolase
XBJ1_2414	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
XBJ1_2418	COG3099	Belongs to the UPF0263 family
XBJ1_2420	COG0444	Belongs to the ABC transporter superfamily
XBJ1_2421	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
XBJ1_2422	COG0601	transmembrane transport
XBJ1_2430	COG1012	belongs to the aldehyde dehydrogenase family
XBJ1_2430	COG1454	alcohol dehydrogenase
XBJ1_2431	COG1435	thymidine kinase activity
XBJ1_2435	COG1210	Utp--glucose-1-phosphate uridylyltransferase
XBJ1_2436	COG0745	RESPONSE REGULATOR receiver
XBJ1_2437	COG3012	SEC-C Motif Domain Protein
XBJ1_2438	COG0788	formyltetrahydrofolate deformylase activity
XBJ1_2442	COG0708	Exodeoxyribonuclease III
XBJ1_2443	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
XBJ1_2444	COG0709	Synthesizes selenophosphate from selenide and ATP
XBJ1_2445	COG0709	Synthesizes selenophosphate from selenide and ATP
XBJ1_2446	COG0778	Nitroreductase
XBJ1_2447	COG0616	signal peptide processing
XBJ1_2448	COG0252	asparaginase activity
XBJ1_2449	COG1335	isochorismatase
XBJ1_2450	COG3139	Protein of unknown function (DUF1315)
XBJ1_2451	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
XBJ1_2454	COG3713	MltA-interacting MipA family protein
XBJ1_2455	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
XBJ1_2456	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XBJ1_2457	COG2186	Transcriptional regulator
XBJ1_2458	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
XBJ1_2460	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
XBJ1_2463	COG0037	tRNA processing
XBJ1_2464	COG0598	Magnesium transport protein CorA
XBJ1_2465	COG4166	transmembrane transport
XBJ1_2467	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
XBJ1_2470	COG3768	UPF0283 membrane protein
XBJ1_2471	COG3106	COG3106 Predicted ATPase
XBJ1_2472	COG1983	PspC domain protein
XBJ1_2474	COG1842	Phage shock protein A
XBJ1_2475	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
XBJ1_2476	COG4166	transmembrane transport
XBJ1_2477	COG4168	peptide transport system, permease
XBJ1_2478	COG4171	peptide transport system, permease
XBJ1_2484	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
XBJ1_2486	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
XBJ1_2487	COG0259	pyridoxamine-phosphate oxidase activity
XBJ1_2488	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
XBJ1_2489	COG3133	Outer membrane lipoprotein
XBJ1_2491	COG0346	lactoylglutathione lyase activity
XBJ1_2492	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
XBJ1_2493	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
XBJ1_2494	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
XBJ1_2496	COG1609	Transcriptional regulator
XBJ1_2497	COG0583	DNA-binding transcription factor activity
XBJ1_2498	COG2814	Major facilitator Superfamily
XBJ1_2500	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
XBJ1_2501	COG0307	riboflavin synthase, alpha
XBJ1_2502	COG0534	Mate efflux family protein
XBJ1_2504	COG4238	major outer membrane lipoprotein
XBJ1_2506	COG1388	LysM domain
XBJ1_2506	COG1376	ErfK ybiS ycfS ynhG family protein
XBJ1_2507	COG2050	protein possibly involved in aromatic compounds catabolism
XBJ1_2508	COG0277	FAD linked oxidase domain protein
XBJ1_2508	COG0247	lactate metabolic process
XBJ1_2509	COG0628	permease
XBJ1_2510	COG0574	Belongs to the PEP-utilizing enzyme family
XBJ1_2510	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
XBJ1_2511	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
XBJ1_2512	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
XBJ1_2513	COG4771	TonB-dependent receptor
XBJ1_2514	COG3720	iron ion transport
XBJ1_2515	COG4558	Periplasmic binding protein
XBJ1_2516	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
XBJ1_2517	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
XBJ1_2521	COG2207	Transcriptional regulator
XBJ1_2522	COG0095	Lipoate-protein ligase
XBJ1_2523	COG0791	NLP P60 protein
XBJ1_2529	COG2076	Multidrug Resistance protein
XBJ1_2530	COG2076	Multidrug Resistance protein
XBJ1_2532	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
XBJ1_2533	COG0726	polysaccharide deacetylase
XBJ1_2534	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
XBJ1_2534	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XBJ1_2535	COG0463	Glycosyl transferase, family 2
XBJ1_2536	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
XBJ1_2537	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
XBJ1_2538	COG4139	cobalamin transport
XBJ1_2539	COG0776	regulation of translation
XBJ1_2540	COG0072	phenylalanine-tRNA ligase activity
XBJ1_2540	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
XBJ1_2543	COG0291	Belongs to the bacterial ribosomal protein bL35 family
XBJ1_2544	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
XBJ1_2545	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
XBJ1_2547	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
XBJ1_2548	COG1988	membrane-bound metal-dependent
XBJ1_2550	COG0501	Belongs to the peptidase M48B family
XBJ1_2552	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
XBJ1_2553	COG1956	GAF domain-containing protein
XBJ1_2555	COG1276	copper resistance
XBJ1_2556	COG2372	response to copper ion
XBJ1_2557	COG1528	Iron-storage protein
XBJ1_2561	COG3140	Belongs to the UPF0181 family
XBJ1_2563	COG0494	nUDIX hydrolase
XBJ1_2564	COG1760	l-serine dehydratase
XBJ1_2565	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
XBJ1_2565	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
XBJ1_2566	COG3715	PTS system
XBJ1_2567	COG3716	PTS system mannose fructose sorbose family IID component
XBJ1_2568	COG4811	Protein of unknown function (DUF986)
XBJ1_2569	COG1971	Probably functions as a manganese efflux pump
XBJ1_2570	COG2226	methyltransferase
XBJ1_2579	COG3335	DDE superfamily endonuclease
XBJ1_2580	COG5433	transposase activity
XBJ1_2583	COG0519	Catalyzes the synthesis of GMP from XMP
XBJ1_2583	COG0518	GMP synthase (glutamine-hydrolyzing) activity
XBJ1_2584	COG0516	GMP reductase activity
XBJ1_2584	COG0517	IMP dehydrogenase activity
XBJ1_2585	COG1570	exodeoxyribonuclease VII activity
XBJ1_2586	COG4206	TonB-dependent receptor
XBJ1_2586	COG1629	transport
XBJ1_2587	COG1770	oligopeptidase
XBJ1_2592	COG2197	response regulator
XBJ1_2594	COG1393	Belongs to the ArsC family
XBJ1_2595	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XBJ1_2596	COG1876	peptidase activity
XBJ1_2598	COG1444	tRNA N-acetyltransferase activity
XBJ1_2599	COG2707	UPF0756 membrane protein
XBJ1_2601	COG3293	Transposase
XBJ1_2605	COG5433	transposase activity
XBJ1_2610	COG1169	isochorismate synthase
XBJ1_2611	COG1021	2,3-dihydroxybenzoate-AMP ligase
XBJ1_2612	COG3433	isochorismatase activity
XBJ1_2612	COG1535	isochorismatase
XBJ1_2613	COG1028	Short-chain dehydrogenase reductase Sdr
XBJ1_2614	COG0662	Cupin 2, conserved barrel domain protein
XBJ1_2615	COG3316	Transposase and inactivated derivatives
XBJ1_2617	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
XBJ1_2618	COG3316	Transposase and inactivated derivatives
XBJ1_2619	COG2233	PERMEase
XBJ1_2620	COG3335	DDE superfamily endonuclease
XBJ1_2621	COG2233	PERMEase
XBJ1_2622	COG3335	DDE superfamily endonuclease
XBJ1_2623	COG2233	PERMEase
XBJ1_2624	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
XBJ1_2625	COG1393	Belongs to the ArsC family
XBJ1_2626	COG4783	chaperone-mediated protein folding
XBJ1_2628	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
XBJ1_2629	COG2716	regulation of RNA biosynthetic process
XBJ1_2630	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
XBJ1_2631	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
XBJ1_2632	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
XBJ1_2638	COG5301	cellulose 1,4-beta-cellobiosidase activity
XBJ1_2639	COG3778	Protein conserved in bacteria
XBJ1_2641	COG4381	Mu-like prophage protein gp46
XBJ1_2642	COG4384	Bacteriophage Mu Gp45 protein
XBJ1_2645	COG3501	Rhs element vgr protein
XBJ1_2657	COG4133	protoheme IX ABC transporter activity
XBJ1_2659	COG0582	viral genome integration into host DNA
XBJ1_2673	COG0582	viral genome integration into host DNA
XBJ1_2674	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
XBJ1_2675	COG0322	excinuclease ABC activity
XBJ1_2676	COG2197	response regulator
XBJ1_2679	COG1943	Transposase
XBJ1_2685	COG3316	Transposase and inactivated derivatives
XBJ1_2687	COG1250	3-hydroxyacyl-CoA dehydrogenase
XBJ1_2693	COG4615	Cyclic peptide transporter
XBJ1_2694	COG1028	Short-chain dehydrogenase reductase Sdr
XBJ1_2694	COG3321	synthase
XBJ1_2694	COG0604	alcohol dehydrogenase
XBJ1_2696	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
XBJ1_2699	COG1960	acyl-CoA dehydrogenase activity
XBJ1_2703	COG1677	Flagellar hook-basal body complex protein FliE
XBJ1_2704	COG1766	The M ring may be actively involved in energy transduction
XBJ1_2705	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
XBJ1_2707	COG1157	protein secretion by the type III secretion system
XBJ1_2708	COG2882	bacterial-type flagellum organization
XBJ1_2709	COG3144	bacterial-type flagellum assembly
XBJ1_2711	COG1580	Controls the rotational direction of flagella during chemotaxis
XBJ1_2716	COG1987	bacterial-type flagellum assembly
XBJ1_2718	COG1028	Short-chain dehydrogenase reductase Sdr
XBJ1_2730	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XBJ1_2731	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XBJ1_2732	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XBJ1_2733	COG2205	protein histidine kinase activity
XBJ1_2734	COG0745	RESPONSE REGULATOR receiver
XBJ1_2738	COG1830	Aldolase
XBJ1_2739	COG0351	phosphomethylpyrimidine kinase
XBJ1_2741	COG1278	Cold shock
XBJ1_2742	COG1113	amino acid transport
XBJ1_2745	COG2207	Transcriptional regulator
XBJ1_2746	COG3023	N-Acetylmuramoyl-L-alanine amidase
XBJ1_2747	COG1115	amino acid carrier protein
XBJ1_2751	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
XBJ1_2753	COG3335	DDE superfamily endonuclease
XBJ1_2756	COG0814	amino acid
XBJ1_2767	COG3335	DDE superfamily endonuclease
XBJ1_2773	COG0583	DNA-binding transcription factor activity
XBJ1_2776	COG1113	amino acid transport
XBJ1_2779	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
XBJ1_2784	COG0640	Transcriptional regulator
XBJ1_2786	COG2801	Transposase and inactivated derivatives
XBJ1_2789	COG3385	transposase activity
XBJ1_2801	COG3335	DDE superfamily endonuclease
XBJ1_2804	COG1605	Chorismate mutase
XBJ1_2805	COG3293	Transposase
XBJ1_2816	COG5301	cellulose 1,4-beta-cellobiosidase activity
XBJ1_2822	COG0538	isocitrate dehydrogenase activity
XBJ1_2823	COG0582	viral genome integration into host DNA
XBJ1_2827	COG0582	viral genome integration into host DNA
XBJ1_2828	COG0538	isocitrate dehydrogenase activity
XBJ1_2829	COG1187	pseudouridine synthase activity
XBJ1_2831	COG0482	sulfurtransferase activity
XBJ1_2832	COG2915	High frequency lysogenization protein hflD homolog
XBJ1_2833	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
XBJ1_2835	COG0745	RESPONSE REGULATOR receiver
XBJ1_2836	COG2205	protein histidine kinase activity
XBJ1_2837	COG2850	peptidyl-arginine hydroxylation
XBJ1_2838	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
XBJ1_2839	COG4591	ABC-type transport system involved in lipoprotein release permease component
XBJ1_2840	COG1136	(ABC) transporter
XBJ1_2841	COG4591	ABC-type transport system involved in lipoprotein release permease component
XBJ1_2843	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
XBJ1_2845	COG1252	NADH dehydrogenase
XBJ1_2846	COG1472	Belongs to the glycosyl hydrolase 3 family
XBJ1_2848	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
XBJ1_2849	COG0537	adenosine 5'-monophosphoramidase activity
XBJ1_2850	COG0084	hydrolase, TatD family'
XBJ1_2851	COG0470	DNA polymerase III
XBJ1_2852	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
XBJ1_2853	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
XBJ1_2854	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
XBJ1_2855	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
XBJ1_2857	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
XBJ1_2859	COG1028	Short-chain dehydrogenase reductase Sdr
XBJ1_2860	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
XBJ1_2861	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XBJ1_2862	COG0416	fatty acid biosynthetic process
XBJ1_2863	COG0333	Belongs to the bacterial ribosomal protein bL32 family
XBJ1_2864	COG1399	metal-binding, possibly nucleic acid-binding protein
XBJ1_2865	COG0424	maF-like protein
XBJ1_2866	COG0564	pseudouridine synthase activity
XBJ1_2867	COG1530	ribonuclease E activity
XBJ1_2869	COG2926	Belongs to the UPF0265 family
XBJ1_2870	COG2925	Exonuclease
XBJ1_2871	COG0277	FAD linked oxidase domain protein
XBJ1_2872	COG0531	amino acid
XBJ1_2875	COG4771	TonB-dependent receptor
XBJ1_2876	COG1120	ATPase activity
XBJ1_2877	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
XBJ1_2879	COG0833	amino acid
XBJ1_2880	COG0583	DNA-binding transcription factor activity
XBJ1_2881	COG2855	membrane
XBJ1_2883	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
XBJ1_2884	COG1105	Belongs to the carbohydrate kinase PfkB family
XBJ1_2886	COG0494	nUDIX hydrolase
XBJ1_2888	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
XBJ1_2892	COG0671	phosphoesterase, PA-phosphatase related
XBJ1_2893	COG0791	NLP P60 protein
XBJ1_2895	COG2814	Major facilitator Superfamily
XBJ1_2896	COG1187	pseudouridine synthase activity
XBJ1_2897	COG1061	Type III restriction enzyme res subunit
XBJ1_2898	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
XBJ1_2899	COG3081	Nucleoid-associated protein
XBJ1_2900	COG3082	Protein of unknown function (DUF1414)
XBJ1_2910	COG5433	transposase activity
XBJ1_2911	COG3316	Transposase and inactivated derivatives
XBJ1_2912	COG1007	ATP synthesis coupled electron transport
XBJ1_2913	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XBJ1_2914	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
XBJ1_2915	COG0713	ATP synthesis coupled electron transport
XBJ1_2916	COG0839	Belongs to the complex I subunit 6 family
XBJ1_2917	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XBJ1_2918	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
XBJ1_2919	COG1034	ATP synthesis coupled electron transport
XBJ1_2921	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
XBJ1_2922	COG0649	NAD binding
XBJ1_2922	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XBJ1_2923	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XBJ1_2924	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XBJ1_2926	COG0583	DNA-binding transcription factor activity
XBJ1_2928	COG0436	Aminotransferase
XBJ1_2931	COG0471	metal ion transport
XBJ1_2931	COG0490	domain, Protein
XBJ1_2932	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
XBJ1_2934	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
XBJ1_2935	COG0280	phosphate acetyltransferase
XBJ1_2935	COG0857	belongs to the CobB CobQ family
XBJ1_2937	COG1113	amino acid transport
XBJ1_2938	COG2988	succinylglutamate desuccinylase activity
XBJ1_2939	COG3724	N-succinylarginine dihydrolase activity
XBJ1_2940	COG1012	belongs to the aldehyde dehydrogenase family
XBJ1_2941	COG3138	arginine N-succinyltransferase
XBJ1_2942	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
XBJ1_2943	COG0488	(ABC) transporter
XBJ1_2945	COG1131	(ABC) transporter
XBJ1_2948	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XBJ1_2950	COG1028	Short-chain dehydrogenase reductase Sdr
XBJ1_2951	COG2070	2-Nitropropane dioxygenase
XBJ1_2951	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
XBJ1_2956	COG0625	glutathione transferase activity
XBJ1_2957	COG1090	epimerase
XBJ1_2958	COG0163	prenyltransferase activity
XBJ1_2959	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
XBJ1_2960	COG1286	toxin biosynthetic process
XBJ1_2961	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
XBJ1_2962	COG0285	dihydrofolate synthase activity
XBJ1_2963	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
XBJ1_2964	COG0586	Pfam SNARE associated Golgi protein
XBJ1_2965	COG0101	tRNA pseudouridine synthase activity
XBJ1_2966	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
XBJ1_2967	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
XBJ1_2972	COG0642	Histidine kinase
XBJ1_2975	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
XBJ1_2976	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
XBJ1_2976	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XBJ1_2977	COG0456	acetyltransferase
XBJ1_2979	COG3101	peptidyl-lysine hydroxylation
XBJ1_2980	COG0730	response to heat
XBJ1_2981	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
XBJ1_2982	COG2890	protein-(glutamine-N5) methyltransferase activity
XBJ1_2984	COG2986	histidine ammonia-lyase
XBJ1_2985	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
XBJ1_2987	COG0010	Belongs to the arginase family
XBJ1_2988	COG1228	amidohydrolase
XBJ1_2989	COG2840	Smr protein MutS2
XBJ1_2990	COG2062	phosphohistidine phosphatase, SixA
XBJ1_2992	COG1024	Enoyl-CoA hydratase
XBJ1_2992	COG1250	3-hydroxyacyl-CoA dehydrogenase
XBJ1_2993	COG0183	Belongs to the thiolase family
XBJ1_2994	COG3691	Protein conserved in bacteria
XBJ1_3000	COG0408	coproporphyrinogen oxidase activity
XBJ1_3003	COG1160	GTP binding
XBJ1_3004	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XBJ1_3005	COG2976	Protein conserved in bacteria
XBJ1_3006	COG0124	histidyl-tRNA synthetase
XBJ1_3007	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
XBJ1_3011	COG0820	rRNA (adenine-C2-)-methyltransferase activity
XBJ1_3013	COG0105	UTP biosynthetic process
XBJ1_3015	COG3655	Transcriptional regulator
XBJ1_3018	COG4953	penicillin-binding protein 1C
XBJ1_3019	COG2373	Large extracellular alpha-helical protein
XBJ1_3021	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
XBJ1_3022	COG2975	iron-sulfur cluster assembly
XBJ1_3023	COG0633	Ferredoxin
XBJ1_3024	COG0443	Heat shock 70 kDa protein
XBJ1_3025	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
XBJ1_3026	COG0316	Belongs to the HesB IscA family
XBJ1_3027	COG0822	iron-sulfur transferase activity
XBJ1_3028	COG1104	cysteine desulfurase activity
XBJ1_3029	COG1959	2 iron, 2 sulfur cluster binding
XBJ1_3030	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
XBJ1_3032	COG2814	Major facilitator Superfamily
XBJ1_3033	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
XBJ1_3034	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
XBJ1_3034	COG1017	nitric oxide dioxygenase activity
XBJ1_3035	COG0347	Belongs to the P(II) protein family
XBJ1_3036	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
XBJ1_3036	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XBJ1_3037	COG2204	response regulator
XBJ1_3038	COG3170	Tfp pilus assembly protein FimV
XBJ1_3039	COG2205	protein histidine kinase activity
XBJ1_3040	COG0047	phosphoribosylformylglycinamidine synthase activity
XBJ1_3040	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
XBJ1_3041	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
XBJ1_3042	COG0590	tRNA wobble adenosine to inosine editing
XBJ1_3043	COG1418	mRNA catabolic process
XBJ1_3045	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
XBJ1_3055	COG3385	transposase activity
XBJ1_3071	COG1388	LysM domain
XBJ1_3071	COG0741	lytic transglycosylase activity
XBJ1_3072	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XBJ1_3073	COG2226	methyltransferase
XBJ1_3075	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
XBJ1_3077	COG2161	toxin-antitoxin pair type II binding
XBJ1_3078	COG4115	mRNA cleavage
XBJ1_3080	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
XBJ1_3081	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
XBJ1_3090	COG2197	response regulator
XBJ1_3091	COG3328	transposase activity
XBJ1_3093	COG0215	cysteine-tRNA ligase activity
XBJ1_3094	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
XBJ1_3095	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XBJ1_3096	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
XBJ1_3097	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
XBJ1_3098	COG0307	riboflavin synthase, alpha
XBJ1_3101	COG2801	Transposase and inactivated derivatives
XBJ1_3108	COG5433	transposase activity
XBJ1_3112	COG3335	DDE superfamily endonuclease
XBJ1_3116	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
XBJ1_3117	COG3530	Putative quorum-sensing-regulated virulence factor
XBJ1_3118	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
XBJ1_3119	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
XBJ1_3120	COG3115	cell septum assembly
XBJ1_3122	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
XBJ1_3124	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
XBJ1_3127	COG2190	(PTS) system
XBJ1_3129	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
XBJ1_3131	COG4208	sulfate ABC transporter
XBJ1_3132	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
XBJ1_3137	COG0456	acetyltransferase
XBJ1_3142	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
XBJ1_3144	COG0736	holo-[acyl-carrier-protein] synthase activity
XBJ1_3145	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
XBJ1_3146	COG1381	Involved in DNA repair and RecF pathway recombination
XBJ1_3147	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
XBJ1_3148	COG0571	ribonuclease III activity
XBJ1_3149	COG0681	Belongs to the peptidase S26 family
XBJ1_3150	COG0481	GTPase activity
XBJ1_3151	COG3086	response to oxidative stress
XBJ1_3154	COG1595	DNA-templated transcription, initiation
XBJ1_3155	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
XBJ1_3156	COG0513	Belongs to the DEAD box helicase family
XBJ1_3158	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
XBJ1_3159	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
XBJ1_3160	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
XBJ1_3161	COG0497	DNA recombination
XBJ1_3162	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XBJ1_3163	COG2914	Belongs to the UPF0125 (RnfH) family
XBJ1_3164	COG2867	negative regulation of translational initiation
XBJ1_3165	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
XBJ1_3168	COG3335	DDE superfamily endonuclease
XBJ1_3174	COG2190	(PTS) system
XBJ1_3174	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
XBJ1_3174	COG1263	PTS System
XBJ1_3175	COG0363	glucosamine-6-phosphate deaminase activity
XBJ1_3176	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
XBJ1_3177	COG1846	Transcriptional regulator
XBJ1_3177	COG1940	carbohydrate kinase activity
XBJ1_3184	COG1943	Transposase
XBJ1_3188	COG3077	Addiction module antitoxin, RelB DinJ family
XBJ1_3194	COG1662	PFAM IS1 transposase
XBJ1_3195	COG3677	Transposase
XBJ1_3196	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XBJ1_3197	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
XBJ1_3198	COG1702	phosphate starvation-inducible protein PhoH
XBJ1_3199	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
XBJ1_3200	COG4535	Mg2 and Co2 transporter CorC
XBJ1_3201	COG0815	Transfers the fatty acyl group on membrane lipoproteins
XBJ1_3203	COG0765	amino acid transport
XBJ1_3204	COG0765	amino acid transport
XBJ1_3205	COG1126	abc transporter atp-binding protein
XBJ1_3206	COG0495	leucyl-tRNA aminoacylation
XBJ1_3207	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
XBJ1_3208	COG1466	dna polymerase III delta subunit
XBJ1_3210	COG0799	negative regulation of ribosome biogenesis
XBJ1_3211	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
XBJ1_3212	COG0768	penicillin binding
XBJ1_3213	COG0772	Belongs to the SEDS family
XBJ1_3214	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
XBJ1_3215	COG1686	Belongs to the peptidase S11 family
XBJ1_3216	COG2921	Belongs to the UPF0250 family
XBJ1_3217	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
XBJ1_3218	COG0321	lipoyl(octanoyl) transferase activity
XBJ1_3219	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
XBJ1_3220	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
XBJ1_3221	COG1278	Cold shock
XBJ1_3222	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
XBJ1_3226	COG4175	Glycine betaine
XBJ1_3227	COG4176	ABC-type proline glycine betaine transport system permease component
XBJ1_3228	COG2113	Glycine betaine
XBJ1_3229	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
XBJ1_3232	COG1846	Transcriptional regulator
XBJ1_3234	COG1566	PFAM secretion protein HlyD family protein
XBJ1_3235	COG2814	Major facilitator Superfamily
XBJ1_3239	COG3486	L-lysine 6-monooxygenase (NADPH) activity
XBJ1_3240	COG4114	ferric iron reductase
XBJ1_3241	COG1120	ATPase activity
XBJ1_3242	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
XBJ1_3243	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
XBJ1_3244	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
XBJ1_3245	COG4773	Receptor
XBJ1_3248	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
XBJ1_3250	COG0045	succinate-CoA ligase (ADP-forming) activity
XBJ1_3250	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
XBJ1_3250	COG1042	CoA-binding domain protein
XBJ1_3251	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XBJ1_3253	COG5544	Lipoprotein
XBJ1_3257	COG0542	response to heat
XBJ1_3259	COG0564	pseudouridine synthase activity
XBJ1_3260	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XBJ1_3261	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
XBJ1_3262	COG1605	Chorismate mutase
XBJ1_3262	COG0077	Prephenate dehydratase
XBJ1_3263	COG0287	Prephenate dehydrogenase
XBJ1_3263	COG1605	Chorismate mutase
XBJ1_3264	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
XBJ1_3266	COG0335	large ribosomal subunit rRNA binding
XBJ1_3267	COG0336	Belongs to the RNA methyltransferase TrmD family
XBJ1_3268	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
XBJ1_3269	COG0228	four-way junction DNA binding
XBJ1_3270	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
XBJ1_3271	COG4137	Cytochrome C assembly protein
XBJ1_3272	COG4536	flavin adenine dinucleotide binding
XBJ1_3281	COG1854	S-ribosylhomocysteine lyase activity
XBJ1_3282	COG2918	glutathione biosynthetic process
XBJ1_3285	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
XBJ1_3286	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
XBJ1_3289	COG2814	Major facilitator Superfamily
XBJ1_3290	COG0204	Acyl-transferase
XBJ1_3290	COG0318	PFAM AMP-dependent synthetase and ligase
XBJ1_3293	COG0204	Acyl-transferase
XBJ1_3293	COG0318	PFAM AMP-dependent synthetase and ligase
XBJ1_3294	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
XBJ1_3295	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
XBJ1_3296	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
XBJ1_3299	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
XBJ1_3301	COG2195	Cleaves the N-terminal amino acid of tripeptides
XBJ1_3302	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
XBJ1_3305	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
XBJ1_3306	COG1309	transcriptional regulator
XBJ1_3307	COG1012	belongs to the aldehyde dehydrogenase family
XBJ1_3308	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
XBJ1_3311	COG1629	transport
XBJ1_3315	COG1595	DNA-templated transcription, initiation
XBJ1_3317	COG2991	Protein conserved in bacteria
XBJ1_3318	COG1477	protein flavinylation
XBJ1_3320	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
XBJ1_3321	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
XBJ1_3322	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
XBJ1_3323	COG1805	sodium ion transport
XBJ1_3324	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
XBJ1_3325	COG3034	peptidoglycan biosynthetic process
XBJ1_3326	COG5433	transposase activity
XBJ1_3328	COG0121	glutamine amidotransferase
XBJ1_3329	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
XBJ1_3330	COG1960	acyl-CoA dehydrogenase activity
XBJ1_3331	COG0019	diaminopimelate decarboxylase activity
XBJ1_3332	COG0583	DNA-binding transcription factor activity
XBJ1_3333	COG0583	DNA-binding transcription factor activity
XBJ1_3335	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XBJ1_3336	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
XBJ1_3337	COG1385	rRNA (uridine-N3-)-methyltransferase activity
XBJ1_3338	COG0189	ligase activity
XBJ1_3339	COG1678	Uncharacterized ACR, COG1678
XBJ1_3340	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
XBJ1_3341	COG2805	Type II/IV secretion system protein
XBJ1_3342	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
XBJ1_3343	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
XBJ1_3344	COG0762	integral membrane protein
XBJ1_3345	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
XBJ1_3346	COG0635	Involved in the biosynthesis of porphyrin-containing compound
XBJ1_3347	COG4607	ABC-type enterochelin transport system periplasmic component
XBJ1_3349	COG2066	Belongs to the glutaminase family
XBJ1_3350	COG3171	Protein conserved in bacteria
XBJ1_3351	COG0220	tRNA (guanine-N7-)-methyltransferase activity
XBJ1_3352	COG1194	a g-specific adenine glycosylase
XBJ1_3353	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
XBJ1_3354	COG0741	lytic transglycosylase activity
XBJ1_3355	COG5433	transposase activity
XBJ1_3367	COG0582	viral genome integration into host DNA
XBJ1_3370	COG0305	Participates in initiation and elongation during chromosome replication
XBJ1_3377	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
XBJ1_3383	COG3423	Transcriptional regulator
XBJ1_3421	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
XBJ1_3422	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
XBJ1_3423	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
XBJ1_3424	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
XBJ1_3425	COG4974	Belongs to the 'phage' integrase family
XBJ1_3426	COG0716	FMN binding
XBJ1_3428	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
XBJ1_3430	COG0354	folic acid binding
XBJ1_3432	COG0477	Major facilitator Superfamily
XBJ1_3434	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
XBJ1_3434	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
XBJ1_3435	COG0509	glycine decarboxylation via glycine cleavage system
XBJ1_3436	COG0404	The glycine cleavage system catalyzes the degradation of glycine
XBJ1_3437	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XBJ1_3438	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XBJ1_3439	COG0006	proline dipeptidase activity
XBJ1_3440	COG3079	Belongs to the UPF0149 family
XBJ1_3443	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
XBJ1_3444	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
XBJ1_3445	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
XBJ1_3446	COG0583	DNA-binding transcription factor activity
XBJ1_3449	COG1279	arginine transmembrane transporter activity
XBJ1_3450	COG0668	transmembrane transport
XBJ1_3451	COG3112	Uncharacterised protein family (UPF0231)
XBJ1_3453	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XBJ1_3454	COG0508	dehydrogenase complex catalyzes the overall conversion of
XBJ1_3455	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
XBJ1_3456	COG2186	Transcriptional regulator
XBJ1_3457	COG3725	Membrane protein required for beta-lactamase induction
XBJ1_3458	COG3023	N-Acetylmuramoyl-L-alanine amidase
XBJ1_3459	COG4969	Belongs to the N-Me-Phe pilin family
XBJ1_3460	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
XBJ1_3461	COG1459	type II secretion system
XBJ1_3462	COG0237	dephospho-CoA kinase activity
XBJ1_3463	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
XBJ1_3464	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
XBJ1_3465	COG0494	nUDIX hydrolase
XBJ1_3466	COG0488	(ABC) transporter
XBJ1_3467	COG0653	protein targeting
XBJ1_3470	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
XBJ1_3472	COG0849	cell division
XBJ1_3473	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
XBJ1_3474	COG1181	Belongs to the D-alanine--D-alanine ligase family
XBJ1_3475	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
XBJ1_3476	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
XBJ1_3477	COG0772	Belongs to the SEDS family
XBJ1_3478	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
XBJ1_3479	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
XBJ1_3480	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
XBJ1_3481	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
XBJ1_3482	COG0768	penicillin binding
XBJ1_3483	COG3116	cell division
XBJ1_3484	COG0275	rRNA processing
XBJ1_3485	COG2001	Belongs to the MraZ family
XBJ1_3486	COG1609	Transcriptional regulator
XBJ1_3488	COG0028	Belongs to the TPP enzyme family
XBJ1_3489	COG1022	Amp-dependent synthetase and ligase
XBJ1_3494	COG0473	3-isopropylmalate dehydrogenase activity
XBJ1_3495	COG3066	DNA modification
XBJ1_3497	COG0242	peptide deformylase activity
XBJ1_3498	COG3335	DDE superfamily endonuclease
XBJ1_3499	COG0242	peptide deformylase activity
XBJ1_3500	COG0626	cystathionine gamma-synthase activity
XBJ1_3506	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
XBJ1_3510	COG0521	Mo-molybdopterin cofactor biosynthetic process
XBJ1_3511	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
XBJ1_3512	COG3022	response to hydroperoxide
XBJ1_3514	COG0083	homoserine kinase activity
XBJ1_3517	COG0745	RESPONSE REGULATOR receiver
XBJ1_3518	COG3045	CreA protein
XBJ1_3520	COG2207	Transcriptional regulator
XBJ1_3520	COG3708	Transcriptional regulator
XBJ1_3521	COG0406	alpha-ribazole phosphatase activity
XBJ1_3522	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
XBJ1_3523	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
XBJ1_3524	COG0741	lytic transglycosylase activity
XBJ1_3525	COG0488	(ABC) transporter
XBJ1_3526	COG0577	efflux transmembrane transporter activity
XBJ1_3526	COG1136	(ABC) transporter
XBJ1_3528	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
XBJ1_3529	COG0560	Phosphoserine phosphatase
XBJ1_3530	COG3726	membrane protein affecting hemolysin expression
XBJ1_3532	COG0582	viral genome integration into host DNA
XBJ1_3536	COG3121	Chaperone
XBJ1_3537	COG3188	usher protein
XBJ1_3538	COG3539	Fimbrial protein
XBJ1_3539	COG0813	purine-nucleoside phosphorylase activity
XBJ1_3540	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
XBJ1_3541	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
XBJ1_3542	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
XBJ1_3543	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
XBJ1_3544	COG0084	hydrolase, TatD family'
XBJ1_3545	COG4667	esterase of the alpha-beta hydrolase superfamily
XBJ1_3548	COG2823	Periplasmic or secreted lipoprotein
XBJ1_3549	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
XBJ1_3551	COG0456	acetyltransferase
XBJ1_3552	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
XBJ1_3553	COG2813	Specifically methylates the guanine in position
XBJ1_3555	COG1012	belongs to the aldehyde dehydrogenase family
XBJ1_3557	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XBJ1_3561	COG3423	Transcriptional regulator
XBJ1_3562	COG2076	Multidrug Resistance protein
XBJ1_3567	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
XBJ1_3568	COG1509	lysine 2,3-aminomutase activity
XBJ1_3570	COG0459	protein refolding
XBJ1_3573	COG1027	Aspartate ammonia-lyase
XBJ1_3575	COG1278	Cold shock
XBJ1_3579	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
XBJ1_3582	COG4942	peptidase
XBJ1_3582	COG1388	LysM domain
XBJ1_3583	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
XBJ1_3584	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
XBJ1_3589	COG3316	Transposase and inactivated derivatives
XBJ1_3595	COG1662	PFAM IS1 transposase
XBJ1_3596	COG3677	Transposase
XBJ1_3599	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
XBJ1_3600	COG2368	4-hydroxyphenylacetate
XBJ1_3601	COG0585	pseudouridine synthase activity
XBJ1_3602	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
XBJ1_3603	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
XBJ1_3606	COG0529	Catalyzes the synthesis of activated sulfate
XBJ1_3607	COG2895	sulfate adenylyltransferase (ATP) activity
XBJ1_3608	COG0175	sulfate reduction
XBJ1_3609	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
XBJ1_3609	COG1648	precorrin-2 dehydrogenase activity
XBJ1_3610	COG0175	sulfate reduction
XBJ1_3611	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
XBJ1_3612	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
XBJ1_3613	COG0720	synthase
XBJ1_3614	COG0602	queuosine metabolic process
XBJ1_3616	COG3021	interspecies interaction between organisms
XBJ1_3617	COG3012	SEC-C Motif Domain Protein
XBJ1_3618	COG0024	Methionine aminopeptidase
XBJ1_3619	COG2194	sulfuric ester hydrolase activity
XBJ1_3620	COG1966	Carbon starvation protein
XBJ1_3621	COG2879	small protein
XBJ1_3622	COG0523	cobalamin synthesis protein
XBJ1_3623	COG0582	viral genome integration into host DNA
XBJ1_3624	COG0814	amino acid
XBJ1_3630	COG0534	Mate efflux family protein
XBJ1_3631	COG3842	ATPase activity
XBJ1_3633	COG1840	ABC-type Fe3 transport system, periplasmic component
XBJ1_3641	COG1166	arginine decarboxylase activity
XBJ1_3643	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
XBJ1_3644	COG3091	SprT-like family
XBJ1_3648	COG1301	dicarboxylic acid transport
XBJ1_3650	COG0471	metal ion transport
XBJ1_3651	COG0148	phosphopyruvate hydratase activity
XBJ1_3652	COG0504	CTP synthase activity
XBJ1_3653	COG3956	TIGRFAM MazG family protein
XBJ1_3654	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
XBJ1_3655	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
XBJ1_3658	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
XBJ1_3659	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
XBJ1_3660	COG0316	Belongs to the HesB IscA family
XBJ1_3661	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
XBJ1_3664	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
XBJ1_3665	COG1643	Atp-dependent helicase
XBJ1_3666	COG1489	DNA binding
XBJ1_3667	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
XBJ1_3668	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
XBJ1_3670	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
XBJ1_3672	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
XBJ1_3673	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
XBJ1_3678	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
XBJ1_3679	COG0842	Transport permease protein
XBJ1_3680	COG1131	(ABC) transporter
XBJ1_3681	COG0288	reversible hydration of carbon dioxide
XBJ1_3685	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
XBJ1_3686	COG1178	ABC-type Fe3 transport system permease component
XBJ1_3687	COG4143	(ABC) transporter
XBJ1_3688	COG0494	nUDIX hydrolase
XBJ1_3690	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
XBJ1_3691	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
XBJ1_3692	COG3335	DDE superfamily endonuclease
XBJ1_3694	COG4795	General secretion pathway protein
XBJ1_3697	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
XBJ1_3699	COG1074	ATP-dependent DNA helicase activity
XBJ1_3700	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
XBJ1_3701	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
XBJ1_3701	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
XBJ1_3703	COG0860	N-Acetylmuramoyl-L-alanine amidase
XBJ1_3706	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
XBJ1_3707	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
XBJ1_3708	COG2166	iron-sulfur cluster assembly
XBJ1_3709	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
XBJ1_3711	COG2992	FlgJ-related protein
XBJ1_3714	COG1696	Membrane protein involved in D-alanine export
XBJ1_3722	COG2610	gluconate transmembrane transporter activity
XBJ1_3723	COG3265	gluconokinase activity
XBJ1_3724	COG1609	Transcriptional regulator
XBJ1_3725	COG1609	Transcriptional regulator
XBJ1_3726	COG1486	melibiose metabolic process
XBJ1_3728	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
XBJ1_3732	COG1309	transcriptional regulator
XBJ1_3733	COG2814	Major facilitator Superfamily
XBJ1_3743	COG2249	NAD(P)H dehydrogenase (quinone) activity
XBJ1_3749	COG1203	CRISPR-associated helicase, Cas3
XBJ1_3755	COG1518	maintenance of DNA repeat elements
XBJ1_3756	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
XBJ1_3766	COG0583	DNA-binding transcription factor activity
XBJ1_3770	COG0367	asparagine synthase
XBJ1_3773	COG0367	asparagine synthase
XBJ1_3774	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
XBJ1_3787	COG3423	Transcriptional regulator
XBJ1_3788	COG3423	Transcriptional regulator
XBJ1_3790	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
XBJ1_3791	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
XBJ1_3792	COG2264	protein methyltransferase activity
XBJ1_3793	COG4145	pantothenate transmembrane transporter activity
XBJ1_3794	COG3924	membrane
XBJ1_3797	COG0439	Biotin carboxylase
XBJ1_3798	COG0511	ligase activity, forming carbon-carbon bonds
XBJ1_3799	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
XBJ1_3800	COG0604	alcohol dehydrogenase
XBJ1_3802	COG1077	Cell shape determining protein MreB Mrl
XBJ1_3803	COG1792	Involved in formation and maintenance of cell shape
XBJ1_3804	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
XBJ1_3805	COG0424	maF-like protein
XBJ1_3806	COG1530	ribonuclease E activity
XBJ1_3808	COG3164	Protein of unknown function
XBJ1_3809	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XBJ1_3810	COG0312	modulator of DNA gyrase
XBJ1_3812	COG2732	(Barnase) inhibitor
XBJ1_3813	COG3335	DDE superfamily endonuclease
XBJ1_3814	COG3028	Belongs to the UPF0307 family
XBJ1_3815	COG0312	modulator of DNA gyrase
XBJ1_3816	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XBJ1_3819	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
XBJ1_3820	COG1660	Displays ATPase and GTPase activities
XBJ1_3821	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
XBJ1_3823	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
XBJ1_3824	COG1137	ATPase activity
XBJ1_3825	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
XBJ1_3826	COG3117	lipopolysaccharide transmembrane transporter activity
XBJ1_3827	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
XBJ1_3828	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
XBJ1_3828	COG0517	IMP dehydrogenase activity
XBJ1_3829	COG0530	calcium, potassium:sodium antiporter activity
XBJ1_3830	COG1127	ABC transporter
XBJ1_3831	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
XBJ1_3832	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
XBJ1_3833	COG2854	intermembrane phospholipid transfer
XBJ1_3835	COG5007	Belongs to the BolA IbaG family
XBJ1_3836	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
XBJ1_3838	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XBJ1_3839	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XBJ1_3841	COG3105	Protein conserved in bacteria
XBJ1_3843	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
XBJ1_3844	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
XBJ1_3845	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
XBJ1_3846	COG0625	glutathione transferase activity
XBJ1_3847	COG2969	positive regulation of protein catabolic process
XBJ1_3851	COG0493	'glutamate synthase
XBJ1_3852	COG0067	glutamate synthase
XBJ1_3852	COG0069	glutamate synthase activity
XBJ1_3852	COG0070	glutamate synthase
XBJ1_3853	COG5002	protein histidine kinase activity
XBJ1_3853	COG2198	Histidine kinase
XBJ1_3853	COG0784	Response regulator, receiver
XBJ1_3855	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
XBJ1_3856	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
XBJ1_3857	COG2823	Periplasmic or secreted lipoprotein
XBJ1_3858	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
XBJ1_3859	COG0792	nuclease activity
XBJ1_3861	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
XBJ1_3862	COG1741	Belongs to the pirin family
XBJ1_3863	COG0583	DNA-binding transcription factor activity
XBJ1_3864	COG2259	Doxx family
XBJ1_3867	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
XBJ1_3868	COG4575	ribosome binding
XBJ1_3869	COG0586	Pfam SNARE associated Golgi protein
XBJ1_3870	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
XBJ1_3871	COG1902	pentaerythritol trinitrate reductase activity
XBJ1_3871	COG0446	pyridine nucleotide-disulphide oxidoreductase
XBJ1_3873	COG2990	Protein conserved in bacteria
XBJ1_3880	COG2345	Transcriptional regulator
XBJ1_3884	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
XBJ1_3885	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
XBJ1_3893	COG3335	DDE superfamily endonuclease
XBJ1_3897	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
XBJ1_3898	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XBJ1_3903	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
XBJ1_3906	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
XBJ1_3911	COG1448	Aminotransferase
XBJ1_3912	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
XBJ1_3913	COG0305	Participates in initiation and elongation during chromosome replication
XBJ1_3925	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
XBJ1_3953	COG1802	Transcriptional regulator
XBJ1_3953	COG4626	Terminase
XBJ1_3968	COG0484	heat shock protein binding
XBJ1_3996	COG0735	belongs to the Fur family
XBJ1_3997	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
XBJ1_3998	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
XBJ1_3999	COG2937	Belongs to the GPAT DAPAT family
XBJ1_4000	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
XBJ1_4001	COG3161	chorismate lyase activity
XBJ1_4002	COG0166	Belongs to the GPI family
XBJ1_4003	COG0527	aspartate kinase activity
XBJ1_4005	COG0800	Aldolase
XBJ1_4007	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
XBJ1_4008	COG2224	Isocitrate lyase
XBJ1_4009	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
XBJ1_4010	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
XBJ1_4018	COG0138	bifunctional purine biosynthesis protein purh
XBJ1_4019	COG0151	Belongs to the GarS family
XBJ1_4021	COG0776	regulation of translation
XBJ1_4022	COG3068	Protein conserved in bacteria
XBJ1_4023	COG1515	deoxyribonuclease V activity
XBJ1_4024	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
XBJ1_4025	COG2816	NAD+ diphosphatase activity
XBJ1_4028	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
XBJ1_4029	COG0352	thiamine-phosphate diphosphorylase activity
XBJ1_4030	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
XBJ1_4032	COG2022	thiamine diphosphate biosynthetic process
XBJ1_4035	COG2223	nitrite transmembrane transporter activity
XBJ1_4036	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
XBJ1_4037	COG1064	alcohol dehydrogenase
XBJ1_4038	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
XBJ1_4039	COG2909	trisaccharide binding
XBJ1_4042	COG0058	SHG alpha-glucan phosphorylase activity
XBJ1_4043	COG1640	4-alpha-glucanotransferase
XBJ1_4044	COG3833	ABC-type maltose transport systems, permease component
XBJ1_4045	COG1175	transmembrane transport
XBJ1_4048	COG3842	ATPase activity
XBJ1_4049	COG4580	involved in the transport of maltose and maltodextrins
XBJ1_4052	COG0726	polysaccharide deacetylase
XBJ1_4053	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
XBJ1_4054	COG0085	RNA polymerase activity
XBJ1_4055	COG0222	ribosome binding
XBJ1_4056	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
XBJ1_4057	COG0081	regulation of translation
XBJ1_4058	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
XBJ1_4059	COG0250	Participates in transcription elongation, termination and antitermination
XBJ1_4060	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
XBJ1_4063	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
XBJ1_4064	COG0049	tRNA binding
XBJ1_4065	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
XBJ1_4066	COG2168	tRNA wobble position uridine thiolation
XBJ1_4067	COG2923	Belongs to the DsrF TusC family
XBJ1_4068	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
XBJ1_4069	COG2964	Protein conserved in bacteria
XBJ1_4070	COG0545	Peptidyl-prolyl cis-trans isomerase
XBJ1_4071	COG2900	Belongs to the SlyX family
XBJ1_4072	COG1047	Peptidyl-prolyl cis-trans
XBJ1_4074	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
XBJ1_4076	COG2249	NAD(P)H dehydrogenase (quinone) activity
XBJ1_4077	COG0488	(ABC) transporter
XBJ1_4080	COG0583	DNA-binding transcription factor activity
XBJ1_4082	COG1662	PFAM IS1 transposase
XBJ1_4084	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
XBJ1_4085	COG1263	PTS System
XBJ1_4085	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
XBJ1_4087	COG3089	Belongs to the UPF0270 family
XBJ1_4088	COG3954	Phosphoribulokinase
XBJ1_4092	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
XBJ1_4093	COG0218	Necessary for normal cell division and for the maintenance of normal septation
XBJ1_4096	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
XBJ1_4096	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
XBJ1_4098	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
XBJ1_4099	COG0746	molybdenum cofactor guanylyltransferase activity
XBJ1_4100	COG1763	Mo-molybdopterin cofactor biosynthetic process
XBJ1_4103	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
XBJ1_4104	COG1830	Aldolase
XBJ1_4105	COG1879	ABC-type sugar transport system periplasmic component
XBJ1_4108	COG2390	Transcriptional regulator
XBJ1_4109	COG1070	Carbohydrate kinase
XBJ1_4110	COG3550	peptidyl-serine autophosphorylation
XBJ1_4111	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XBJ1_4112	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
XBJ1_4114	COG3423	Transcriptional regulator
XBJ1_4116	COG5301	cellulose 1,4-beta-cellobiosidase activity
XBJ1_4121	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
XBJ1_4127	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
XBJ1_4129	COG1511	domain protein
XBJ1_4129	COG3264	Mechanosensitive ion channel
XBJ1_4130	COG0688	phosphatidylethanolamine metabolic process
XBJ1_4131	COG1162	GTPase activity
XBJ1_4132	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
XBJ1_4141	COG3152	Membrane
XBJ1_4142	COG0561	phosphatase activity
XBJ1_4143	COG2267	carboxylic ester hydrolase activity
XBJ1_4144	COG0514	ATP-dependent DNA helicase (RecQ)
XBJ1_4146	COG2050	protein possibly involved in aromatic compounds catabolism
XBJ1_4150	COG0598	Magnesium transport protein CorA
XBJ1_4151	COG0210	DNA helicase
XBJ1_4152	COG1011	Hydrolase
XBJ1_4154	COG3159	Protein conserved in bacteria
XBJ1_4155	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
XBJ1_4156	COG5567	small periplasmic lipoprotein
XBJ1_4157	COG1965	Belongs to the frataxin family
XBJ1_4160	COG0181	hydroxymethylbilane synthase activity
XBJ1_4162	COG2959	enzyme of heme biosynthesis
XBJ1_4163	COG3071	HemY protein
XBJ1_4166	COG1113	amino acid transport
XBJ1_4167	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
XBJ1_4169	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
XBJ1_4170	COG2244	polysaccharide biosynthetic process
XBJ1_4171	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
XBJ1_4172	COG0456	acetyltransferase
XBJ1_4173	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
XBJ1_4174	COG1088	dTDP-glucose 4,6-dehydratase activity
XBJ1_4175	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
XBJ1_4176	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
XBJ1_4177	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
XBJ1_4178	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
XBJ1_4179	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
XBJ1_4182	COG3118	belongs to the thioredoxin family
XBJ1_4184	COG0513	Belongs to the DEAD box helicase family
XBJ1_4185	COG0248	Ppx GppA phosphatase
XBJ1_4186	COG0210	DNA helicase
XBJ1_4189	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
XBJ1_4190	COG0583	DNA-binding transcription factor activity
XBJ1_4192	COG0129	dihydroxy-acid dehydratase activity
XBJ1_4193	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
XBJ1_4194	COG3978	acetolactate synthase activity
XBJ1_4197	COG3085	chromosome segregation
XBJ1_4198	COG0583	DNA-binding transcription factor activity
XBJ1_4204	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
XBJ1_4206	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
XBJ1_4207	COG0009	L-threonylcarbamoyladenylate synthase
XBJ1_4208	COG0551	DNA topoisomerase type I activity
XBJ1_4209	COG0758	DNA mediated transformation
XBJ1_4210	COG0242	peptide deformylase activity
XBJ1_4211	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
XBJ1_4212	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
XBJ1_4212	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
XBJ1_4213	COG0569	domain protein
XBJ1_4214	COG3036	rescue of stalled ribosome
XBJ1_4215	COG0789	Transcriptional regulator
XBJ1_4216	COG0203	ribosomal protein L17
XBJ1_4217	COG0202	RNA polymerase activity
XBJ1_4218	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
XBJ1_4220	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
XBJ1_4221	COG0201	protein transport
XBJ1_4222	COG0200	Binds to the 23S rRNA
XBJ1_4223	COG1841	ribosomal large subunit assembly
XBJ1_4224	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
XBJ1_4225	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
XBJ1_4226	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
XBJ1_4227	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
XBJ1_4228	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
XBJ1_4229	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
XBJ1_4231	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
XBJ1_4232	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
XBJ1_4233	COG0255	Belongs to the universal ribosomal protein uL29 family
XBJ1_4234	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
XBJ1_4236	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
XBJ1_4237	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
XBJ1_4238	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
XBJ1_4239	COG0089	rRNA binding
XBJ1_4240	COG0088	Forms part of the polypeptide exit tunnel
XBJ1_4241	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
XBJ1_4242	COG0051	transcription antitermination factor activity, RNA binding
XBJ1_4251	COG1072	(Pantothenic acid kinase))
XBJ1_4253	COG0812	UDP-N-acetylmuramate dehydrogenase activity
XBJ1_4259	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
XBJ1_4260	COG4206	TonB-dependent receptor
XBJ1_4262	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
XBJ1_4265	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XBJ1_4268	COG0165	Argininosuccinate lyase
XBJ1_4269	COG0137	argininosuccinate synthase activity
XBJ1_4270	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
XBJ1_4271	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
XBJ1_4272	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XBJ1_4275	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
XBJ1_4276	COG0460	homoserine dehydrogenase
XBJ1_4276	COG0527	aspartate kinase activity
XBJ1_4277	COG0626	cystathionine gamma-synthase activity
XBJ1_4279	COG0254	rRNA binding
XBJ1_4280	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
XBJ1_4282	COG1609	Transcriptional regulator
XBJ1_4283	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
XBJ1_4284	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
XBJ1_4285	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
XBJ1_4286	COG1575	Belongs to the MenA family. Type 1 subfamily
XBJ1_4287	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
XBJ1_4288	COG3074	FtsZ-dependent cytokinesis
XBJ1_4291	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
XBJ1_4292	COG2814	Major facilitator Superfamily
XBJ1_4294	COG3152	Membrane
XBJ1_4297	COG0149	triose-phosphate isomerase activity
XBJ1_4301	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
XBJ1_4302	COG0205	6-phosphofructokinase activity
XBJ1_4303	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
XBJ1_4304	COG4589	Belongs to the CDS family
XBJ1_4310	COG3678	ATP-independent chaperone mediated protein folding
XBJ1_4311	COG0745	RESPONSE REGULATOR receiver
XBJ1_4312	COG2205	protein histidine kinase activity
XBJ1_4314	COG0673	inositol 2-dehydrogenase activity
XBJ1_4320	COG0482	sulfurtransferase activity
XBJ1_4327	COG1215	transferase activity, transferring glycosyl groups
XBJ1_4329	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
XBJ1_4330	COG1045	serine acetyltransferase
XBJ1_4331	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
XBJ1_4332	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
XBJ1_4333	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
XBJ1_4334	COG4942	peptidase
XBJ1_4335	COG2861	carbohydrate metabolic process
XBJ1_4336	COG1063	alcohol dehydrogenase
XBJ1_4337	COG0156	8-amino-7-oxononanoate synthase activity
XBJ1_4338	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XBJ1_4343	COG1216	Glycosyl transferase, family 2
XBJ1_4346	COG0859	PFAM glycosyl transferase family 9
XBJ1_4348	COG0297	glycogen (starch) synthase activity
XBJ1_4348	COG0438	transferase activity, transferring glycosyl groups
XBJ1_4349	COG1519	Transferase
XBJ1_4351	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
XBJ1_4352	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
XBJ1_4355	COG0438	transferase activity, transferring glycosyl groups
XBJ1_4357	COG0438	transferase activity, transferring glycosyl groups
XBJ1_4358	COG0267	Belongs to the bacterial ribosomal protein bL33 family
XBJ1_4361	COG2003	Belongs to the UPF0758 family
XBJ1_4362	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
XBJ1_4363	COG0756	dUTP diphosphatase activity
XBJ1_4364	COG1309	transcriptional regulator
XBJ1_4365	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
XBJ1_4366	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
XBJ1_4367	COG1561	YicC-like family, N-terminal region
XBJ1_4382	COG3645	SOS response
XBJ1_4387	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XBJ1_4389	COG2188	Transcriptional regulator
XBJ1_4390	COG1368	sulfuric ester hydrolase activity
XBJ1_4391	COG3058	Necessary for formate dehydrogenase activity
XBJ1_4402	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
XBJ1_4408	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
XBJ1_4409	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
XBJ1_4410	COG0706	membrane insertase activity
XBJ1_4411	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
XBJ1_4412	COG0594	ribonuclease P activity
XBJ1_4413	COG0230	Belongs to the bacterial ribosomal protein bL34 family