locus-tag	class	description
XDD1_0001	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
XDD1_0002	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
XDD1_0003	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
XDD1_0004	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
XDD1_0009	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
XDD1_0013	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
XDD1_0030	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
XDD1_0031	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
XDD1_0033	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
XDD1_0034	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
XDD1_0035	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
XDD1_0036	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
XDD1_0037	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
XDD1_0038	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
XDD1_0039	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
XDD1_0040	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
XDD1_0041	ENOG4105GXX	Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation
XDD1_0042	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
XDD1_0043	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
XDD1_0044	ENOG4105QTB	Flavodoxin
XDD1_0045	ENOG4108VVK	transcriptional Regulator, AsnC
XDD1_0046	ENOG4105CU9	asparagine synthetase A
XDD1_0047	ENOG4105EV2	VWA domain protein interacting with AAA ATPase
XDD1_0048	ENOG4107R4Q	Functions as an ATPase. May play a role in metal insertion (metal-chelatase) or as a chaperone (By similarity)
XDD1_0049	ENOG4105C2J	ABC transporter
XDD1_0050	ENOG4105CNN	ABC, transporter
XDD1_0051	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
XDD1_0052	ENOG4108RVA	ribokinase
XDD1_0053	ENOG4105ETE	Transcriptional regulator (LacI family
XDD1_0054	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
XDD1_0058	ENOG4107QN1	sodium solute
XDD1_0059	ENOG41062QD	Membrane
XDD1_0061	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
XDD1_0062	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
XDD1_0064	ENOG4108RPX	mosc domain containing protein
XDD1_0065	ENOG4105C31	Tryptophanyl-tRNA synthetase
XDD1_0066	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
XDD1_0067	ENOG4105DJV	ribulose-phosphate 3-epimerase
XDD1_0070	ENOG4105D49	3-dehydroquinate synthase
XDD1_0071	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
XDD1_0072	ENOG4105E4G	Type IV pilus
XDD1_0076	ENOG4108JQC	penicillin-binding protein 1A
XDD1_0077	ENOG4107RK2	ADP-ribose diphosphatase NudE
XDD1_0078	ENOG4105DQY	intracellular growth attenuator
XDD1_0079	ENOG4105VEJ	Heat shock protein
XDD1_0080	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
XDD1_0081	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
XDD1_0082	ENOG4105E5M	Multidrug resistance protein D
XDD1_0085	ENOG4105DZS	Phenylacetate-CoA ligase
XDD1_0087	ENOG4105F27	Major Facilitator
XDD1_0089	ENOG4106NZI	LysR family Transcriptional regulator
XDD1_0090	ENOG4105CBX	hi0933 family
XDD1_0091	ENOG4105CJ3	phosphate transporter
XDD1_0092	ENOG4108V6B	universal stress protein B
XDD1_0094	ENOG4108M6U	Universal stress protein A
XDD1_0096	ENOG4105D82	Glutamate dehydrogenase
XDD1_0097	ENOG4105FFN	Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity)
XDD1_0098	ENOG4105DGW	oligopeptidase A
XDD1_0100	ENOG4105C22	threonyL-tRNA synthetase
XDD1_0104	ENOG4105CG3	alpha amylase, catalytic region
XDD1_0105	ENOG4105C5Y	PTS System
XDD1_0107	ENOG4105V9J	phenylacetic acid degradation operon negative regulatory protein
XDD1_0108	ENOG4105EJC	lysr family transcriptional regulator
XDD1_0112	ENOG41060M8	Pfam:PhdYeFM
XDD1_0113	ENOG4105DSJ	YicC domain protein
XDD1_0115	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
XDD1_0116	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
XDD1_0118	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
XDD1_0119	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
XDD1_0120	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
XDD1_0122	ENOG4105W5Q	DNA repair protein (RadC
XDD1_0125	ENOG4105W0E	50S ribosomal protein L33
XDD1_0127	ENOG4105CPK	Glycosyl transferase (Group 1
XDD1_0129	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
XDD1_0131	ENOG4108FRV	O-antigen ligase
XDD1_0132	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
XDD1_0133	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
XDD1_0135	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
XDD1_0136	ENOG4105DKP	glycosyl transferase, family 9
XDD1_0138	ENOG4105CPK	Glycosyl transferase (Group 1
XDD1_0141	ENOG4107S6X	Glycosyl transferase, family 2
XDD1_0144	ENOG4105D16	lipopolysaccharide heptosyltransferase i
XDD1_0145	ENOG4105XA0	heptosyltransferase ii
XDD1_0146	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
XDD1_0147	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
XDD1_0148	ENOG4105CPQ	Dehydrogenase
XDD1_0149	ENOG4105PXI	polysaccharide deacetylase
XDD1_0150	ENOG41063SB	peptidase
XDD1_0155	ENOG4107YZP	Rhodanese domain protein
XDD1_0156	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
XDD1_0157	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
XDD1_0158	ENOG4105D7W	serine acetyltransferase
XDD1_0159	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
XDD1_0162	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
XDD1_0164	ENOG4105C5E	polysaccharide biosynthesis protein
XDD1_0165	ENOG4108TMJ	glycosyl transferase
XDD1_0166	ENOG4107QKV	phosphomannomutase
XDD1_0167	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
XDD1_0171	ENOG4105E0F	Histidine kinase
XDD1_0172	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
XDD1_0173	ENOG4105FMW	periplasmic
XDD1_0182	ENOG4105CTQ	phosphohexokinase
XDD1_0183	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
XDD1_0184	ENOG4105CP7	Triose-phosphate isomerase
XDD1_0185	ENOG4105EBK	exported protein
XDD1_0187	ENOG4108VTS	Membrane
XDD1_0188	ENOG4105DP0	ferredoxin-NADP reductase
XDD1_0189	ENOG4105E5M	Multidrug resistance protein D
XDD1_0190	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
XDD1_0191	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
XDD1_0192	ENOG4105N4M	Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA (By similarity)
XDD1_0193	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
XDD1_0194	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
XDD1_0195	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
XDD1_0196	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
XDD1_0197	ENOG41063M6	Cell Division Protein
XDD1_0198	ENOG4105ETE	Transcriptional regulator (LacI family
XDD1_0199	ENOG4105C25	Primosomal protein n'
XDD1_0201	ENOG4105GGQ	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis (By similarity)
XDD1_0202	ENOG4105C28	cystathionine
XDD1_0203	ENOG4105CFH	Aspartokinase
XDD1_0204	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
XDD1_0205	ENOG4105HEI	LysR family (Transcriptional regulator
XDD1_0206	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
XDD1_0209	ENOG4105DXI	Major Facilitator superfamily
XDD1_0210	ENOG4105SYT	Methylenetetrahydrofolate reductase
XDD1_0215	ENOG4105CWC	Acetylornithine deacetylase
XDD1_0216	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
XDD1_0217	ENOG4105CAS	nag kinase
XDD1_0218	ENOG4105CDH	Citrulline--aspartate ligase
XDD1_0219	ENOG4105CH7	arginosuccinase
XDD1_0229	ENOG4105EQR	Transposase IS116 IS110 IS902
XDD1_0238	ENOG4107QP0	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
XDD1_0249	ENOG4105EQR	Transposase IS116 IS110 IS902
XDD1_0259	ENOG4105C5Q	Transcriptional regulator
XDD1_0260	ENOG4105DX1	Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity)
XDD1_0262	ENOG4108Y73	Membrane
XDD1_0263	ENOG4107R9T	Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity)
XDD1_0264	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
XDD1_0272	ENOG4105D4A	Cell wall formation (By similarity)
XDD1_0273	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
XDD1_0274	ENOG4105CS9	pantothenic acid kinase
XDD1_0277	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
XDD1_0280	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
XDD1_0281	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
XDD1_0282	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
XDD1_0283	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
XDD1_0284	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
XDD1_0285	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
XDD1_0286	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
XDD1_0287	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
XDD1_0288	ENOG41083MP	50s ribosomal protein l29
XDD1_0289	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
XDD1_0290	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
XDD1_0291	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
XDD1_0292	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
XDD1_0293	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
XDD1_0294	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
XDD1_0295	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
XDD1_0296	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
XDD1_0297	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
XDD1_0298	ENOG4105VPB	50S ribosomal protein L30
XDD1_0299	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
XDD1_0300	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
XDD1_0301	ENOG41067V7	50S ribosomal protein L36
XDD1_0302	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
XDD1_0303	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
XDD1_0304	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
XDD1_0305	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
XDD1_0306	ENOG4108ZT0	50S ribosomal protein l17
XDD1_0307	ENOG4105W1Y	Transcriptional regulator
XDD1_0308	ENOG4105VCN	Rescues the ribosomes stalled at the 3' end of non-stop mRNAs. May induce hydrolysis of the ribosome-bound peptidyl-tRNA. This activity is crucial when the stalled ribosome can not be rescued by the SsrA(tmRNA)-SmpB quality control system
XDD1_0309	ENOG4105C1A	potassium transporter peripheral membrane
XDD1_0310	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
XDD1_0311	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
XDD1_0312	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
XDD1_0314	ENOG4105C79	DNA protecting protein DprA
XDD1_0315	ENOG4108WI1	Dna topoisomerase
XDD1_0316	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
XDD1_0317	ENOG4105E2X	shikimate dehydrogenase
XDD1_0318	ENOG4105SG3	Protein of unknown function (DUF1488)
XDD1_0319	ENOG4108Z0R	Transferase
XDD1_0326	ENOG4105CVI	Transcriptional regulator
XDD1_0327	ENOG4108WFC	UPF0438 protein yifE
XDD1_0328	ENOG4105C0P	Mg chelatase subunit ChlI
XDD1_0330	ENOG4105P3Y	Acetolactate synthase 2 regulatory subunit
XDD1_0331	ENOG4105CM2	brancheD-chain amino acid aminotransferase
XDD1_0332	ENOG4105C01	Dihydroxy-acid dehydratase
XDD1_0333	ENOG4105C7B	Threonine dehydratase
XDD1_0334	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
XDD1_0335	ENOG4105CW7	secretion protein, HlyD family
XDD1_0337	ENOG4105EMY	transcriptional regulator
XDD1_0338	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
XDD1_0339	ENOG4105DGU	Histone deacetylase
XDD1_0340	ENOG4105C4R	Atp-dependent dna helicase
XDD1_0341	ENOG4105C9X	ppx gppa phosphatase
XDD1_0342	ENOG4105C1J	atp-dependent rna helicase
XDD1_0343	ENOG4105K63	Thioredoxin
XDD1_0346	ENOG4105ESV	Glycosyl transferase, family 4
XDD1_0347	ENOG4105SFE	lipopolysaccharide biosynthesis protein
XDD1_0348	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
XDD1_0349	ENOG4108IJ1	Dehydrogenase
XDD1_0350	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
XDD1_0351	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
XDD1_0352	ENOG4108WJ1	acetyltransferase
XDD1_0353	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
XDD1_0354	ENOG4105EGZ	biosynthesis protein
XDD1_0355	ENOG4105F18	Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis (By similarity)
XDD1_0356	ENOG4105DAD	Could be involved in ECA polysaccharide chain elongation (By similarity)
XDD1_0357	ENOG4108UHC	Glycosyl transferase, wecb taga cpsf family
XDD1_0358	ENOG4105C85	amino acid
XDD1_0360	ENOG410601J	HemY protein
XDD1_0361	ENOG4105ECF	c-methyltransferase
XDD1_0362	ENOG41076E6	Uroporphyrinogen-III Synthase
XDD1_0363	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
XDD1_0365	ENOG4107T0K	Adenylate cyclase
XDD1_0366	ENOG4105XQ6	frataxin-like protein
XDD1_0367	ENOG4105S7Z	(LipO)protein
XDD1_0368	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
XDD1_0369	ENOG4105CT0	Protein of unknown function, DUF484
XDD1_0371	ENOG4105DFC	had-superfamily hydrolase, subfamily ia, variant
XDD1_0372	ENOG4105C4R	Atp-dependent dna helicase
XDD1_0373	ENOG4107QUT	magnesium and cobalt transport protein CorA
XDD1_0375	ENOG4105FR1	rard protein
XDD1_0379	ENOG4108VUY	thioesterase Superfamily protein
XDD1_0380	ENOG4105HDD	phospholipase
XDD1_0381	ENOG4105C9U	ATP-dependent DNA helicase RecQ
XDD1_0382	ENOG4108EUD	Lysophospholipase
XDD1_0383	ENOG4105DQF	Hydrolase
XDD1_0386	ENOG4105ETE	Transcriptional regulator (LacI family
XDD1_0389	ENOG4105KAF	membrAne
XDD1_0390	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
XDD1_0395	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
XDD1_0397	ENOG4105EGS	Mechanosensitive ion channel
XDD1_0398	ENOG4105DJ4	phosphatidylserine decarboxylase
XDD1_0399	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
XDD1_0403	ENOG4105F27	Major Facilitator
XDD1_0410	ENOG4105CBN	LysR family transcriptional regulator
XDD1_0411	ENOG4105C57	major facilitator superfamily
XDD1_0413	ENOG4105C0F	tryptophanase EC 4.1.99.1
XDD1_0414	ENOG4108KC1	acyl-Coa dehydrogenase
XDD1_0415	ENOG4105EFA	4-hydroxyphenylacetate
XDD1_0416	ENOG4105K8N	protein family UPF0079, ATPase
XDD1_0417	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
XDD1_0418	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
XDD1_0419	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
XDD1_0420	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
XDD1_0422	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
XDD1_0424	ENOG4107QJR	hflk protein
XDD1_0425	ENOG4105EPW	hflc protein
XDD1_0426	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
XDD1_0428	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
XDD1_0430	ENOG4105C2N	RNA methyltransferase TrmH family group 3
XDD1_0431	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
XDD1_0432	ENOG4108VDV	Binds single-stranded DNA at the primosome assembly site (PAS) (By similarity)
XDD1_0433	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
XDD1_0434	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
XDD1_0438	ENOG4108V1T	peptidylprolyl cis-trans isomerase
XDD1_0439	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
XDD1_0440	ENOG4108UUE	Transcriptional regulator
XDD1_0442	ENOG41061GZ	Protein of unknown function (DUF1107)
XDD1_0443	ENOG4105PF0	Antitoxin component of a toxin-antitoxin (TA) module. Functions as an mRNA interferase antitoxin
XDD1_0444	ENOG41063XI	Toxic component of a toxin-antitoxin (TA) module. A
XDD1_0445	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
XDD1_0448	ENOG4108ZHD	aig2 family
XDD1_0449	ENOG4105F0N	pyrophosphate phospho-hydrolase
XDD1_0450	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
XDD1_0452	ENOG4105DFU	Cell wall formation (By similarity)
XDD1_0453	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
XDD1_0455	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
XDD1_0456	ENOG4105HVQ	Regulatory factor of maltose metabolism
XDD1_0459	ENOG4105EAH	synthase
XDD1_0461	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
XDD1_0462	ENOG4105K46	50S ribosomal protein l27
XDD1_0463	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
XDD1_0466	ENOG4105X54	addiction module antidote protein
XDD1_0467	ENOG4106HRJ	d-alanyl-d-alanine carboxypeptidase
XDD1_0469	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
XDD1_0470	ENOG4105HBR	Rna-binding protein
XDD1_0471	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
XDD1_0472	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
XDD1_0473	ENOG4105EEI	dihydropteroate synthase
XDD1_0474	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
XDD1_0476	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
XDD1_0477	ENOG4105CHV	Transcription elongation factor NusA
XDD1_0478	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
XDD1_0479	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
XDD1_0480	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
XDD1_0481	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
XDD1_0482	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
XDD1_0484	ENOG4105C1J	atp-dependent rna helicase
XDD1_0487	ENOG4108NEV	two component transcriptional regulator, LytTR family
XDD1_0488	ENOG4108HRK	Histidine kinase
XDD1_0489	ENOG4105TNG	K13735 adhesin invasin
XDD1_0490	ENOG4107KET	secretion protein, HlyD family
XDD1_0494	ENOG4108YYD	acetyltransferase
XDD1_0497	ENOG4108ZPB	UPF0306 protein
XDD1_0498	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
XDD1_0499	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
XDD1_0501	ENOG4105KME	endoribonuclease L-psp
XDD1_0502	ENOG4108R9M	Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity)
XDD1_0503	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
XDD1_0506	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
XDD1_0511	ENOG4105CXT	aspartate transcarbamylase
XDD1_0514	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
XDD1_0519	ENOG4105EAB	amino acid AbC transporter
XDD1_0520	ENOG4105DRP	amino acid AbC transporter
XDD1_0521	ENOG4105CDA	abc transporter atp-binding protein
XDD1_0522	ENOG4105EAB	amino acid AbC transporter
XDD1_0523	ENOG4105C7F	AcnD-accessory protein PrpF
XDD1_0525	ENOG4105M0J	Toxic component of a toxin-antitoxin (TA) module. A
XDD1_0527	ENOG4108MJ3	acetyltransferase
XDD1_0528	ENOG4105KQT	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity)
XDD1_0529	ENOG4105DBV	ornithine carbamoyltransferase
XDD1_0530	ENOG4105C28	cystathionine
XDD1_0531	ENOG4107S6Z	Na H antiporter
XDD1_0532	ENOG4105K6H	D-cysteine desulfhydrase
XDD1_0544	ENOG4105DNE	Transposase
XDD1_0555	ENOG4105H38	Membrane
XDD1_0556	ENOG4105MZG	transcriptional modulator of maze toxin, mazf
XDD1_0557	ENOG4106A2Z	transcriptional regulator antitoxin, MazE
XDD1_0559	ENOG4105DNE	Transposase
XDD1_0565	ENOG4106IPI	cyclase, family
XDD1_0566	ENOG4105EWK	phytoene
XDD1_0569	ENOG4105C5H	ABC transporter
XDD1_0577	ENOG4105M0J	Toxic component of a toxin-antitoxin (TA) module. A
XDD1_0584	ENOG4105ERH	Fumarylacetoacetate hydrolase
XDD1_0585	ENOG4105ES4	Nitrilase
XDD1_0591	ENOG4105PWE	CRISPR-associated protein cas2
XDD1_0592	ENOG4105TZK	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
XDD1_0594	ENOG4108VWQ	crispr-associated protein
XDD1_0598	ENOG4105DTT	CRISPR-associated helicase, cas3
XDD1_0606	ENOG4105DIQ	Transcriptional regulator
XDD1_0607	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
XDD1_0608	ENOG4105C6Z	Gluconate
XDD1_0618	ENOG4108UR8	BAX protein
XDD1_0621	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
XDD1_0630	ENOG4105DAX	Pfam:DUF2983
XDD1_0633	ENOG4108TEB	UPF0114 protein
XDD1_0637	ENOG4105E93	esterase
XDD1_0638	ENOG4108PCN	EamA-like transporter family
XDD1_0639	ENOG4108T1M	outer membrane protein x
XDD1_0641	ENOG4108SIC	Transcriptional regulator
XDD1_0642	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
XDD1_0643	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
XDD1_0644	ENOG4108IJ0	Aspartate ammonia-lyase
XDD1_0646	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
XDD1_0647	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
XDD1_0648	ENOG4108ZVF	(LipO)protein
XDD1_0649	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
XDD1_0650	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
XDD1_0652	ENOG4105HVQ	Regulatory factor of maltose metabolism
XDD1_0655	ENOG4105CJP	fad dependent oxidoreductase
XDD1_0657	ENOG4105C26	Dehydrogenase
XDD1_0660	ENOG4108BUD	transposase
XDD1_0661	ENOG4107R6D	beta-lactam binding protein AmpH
XDD1_0663	ENOG4108K5H	permease YjgP YjgQ family protein
XDD1_0664	ENOG4108M8S	permease YjgP YjgQ family protein
XDD1_0665	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
XDD1_0666	ENOG4105MYG	DNA polymerase iii, chi subunit
XDD1_0667	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
XDD1_0674	ENOG410829K	Lysine exporter protein (Lyse ygga)
XDD1_0675	ENOG4108IND	Tetr family transcriptional regulator
XDD1_0676	ENOG4107RTG	Major Facilitator superfamily
XDD1_0681	ENOG4106F59	XRE family Transcriptional regulator
XDD1_0686	ENOG4107U32	Beta-lactamase domain protein
XDD1_0687	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
XDD1_0688	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
XDD1_0692	ENOG4105C5H	ABC transporter
XDD1_0693	ENOG4107RUE	extracellular solute-binding protein family 1
XDD1_0694	ENOG4105D38	putrescine abc transporter
XDD1_0695	ENOG4105F38	ABC transporter, permease
XDD1_0696	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
XDD1_0702	ENOG4105EB3	Histidine kinase
XDD1_0704	ENOG41090BB	DNA mismatch endonuclease (vsr)
XDD1_0709	ENOG41084S7	Plasmid maintenance system antidote protein
XDD1_0711	ENOG4107YNJ	LysR family Transcriptional regulator
XDD1_0712	ENOG4105CK2	sodium dicarboxylate symporter
XDD1_0721	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
XDD1_0722	ENOG4108WPU	DNA polymerase III subunit psi
XDD1_0723	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
XDD1_0726	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
XDD1_0728	ENOG4108NRW	Phospholipase, patatin family
XDD1_0729	ENOG4105EYA	deoxyribonuclease
XDD1_0730	ENOG4105D9N	nucleoside
XDD1_0731	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
XDD1_0732	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
XDD1_0733	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
XDD1_0734	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
XDD1_0735	ENOG4105HMV	Fimbrial protein
XDD1_0736	ENOG4106PG1	outer membrane usher protein
XDD1_0737	ENOG4108FZ9	Chaperone
XDD1_0742	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
XDD1_0743	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
XDD1_0744	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
XDD1_0745	ENOG4105EXG	Transcriptional regulator
XDD1_0750	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
XDD1_0751	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
XDD1_0752	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
XDD1_0753	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
XDD1_0754	ENOG4105DTN	riboflavin biosynthesis protein ribF
XDD1_0755	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
XDD1_0756	ENOG41063Z6	transcriptional regulator, lysR family
XDD1_0757	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
XDD1_0759	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
XDD1_0760	ENOG4105CFG	Acts as a chaperone (By similarity)
XDD1_0761	ENOG4106HK8	GPR1 FUN34 yaaH family protein
XDD1_0762	ENOG4105CSH	Transporter
XDD1_0775	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
XDD1_0776	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
XDD1_0777	ENOG4105D1Q	UPF0246 protein
XDD1_0779	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
XDD1_0781	ENOG41065U4	response regulator
XDD1_0782	ENOG4108RH0	Crea protein
XDD1_0784	ENOG4105UEI	Transcriptional Regulator AraC Family
XDD1_0785	ENOG4105CVJ	phosphoglycerate mutase
XDD1_0786	ENOG4108K16	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
XDD1_0787	ENOG4105R9M	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region (By similarity)
XDD1_0788	ENOG4107SC1	transglycosylase
XDD1_0789	ENOG4105C5H	ABC transporter
XDD1_0790	ENOG4105CDA	abc transporter atp-binding protein
XDD1_0791	ENOG4107VZS	Nicotinamide-nucleotide adenylyltransferase
XDD1_0792	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
XDD1_0793	ENOG4105EAC	phosphoserine phosphatase
XDD1_0794	ENOG41062Z9	Membrane
XDD1_0796	ENOG4105CV8	reductase
XDD1_0797	ENOG4108K81	inner membrane protein YghB
XDD1_0798	ENOG4105C28	cystathionine
XDD1_0799	ENOG4105CWK	Biopolymer transport protein, ExbB
XDD1_0800	ENOG4108ZZF	transport protein (ExbD)
XDD1_0803	ENOG4105KRI	phosphocarrier protein (HPr
XDD1_0804	ENOG4105CS2	ec 3.2.1.21
XDD1_0806	ENOG4105CK1	PTS System
XDD1_0811	ENOG4105FCK	Membrane
XDD1_0812	ENOG4105DH7	May be involved in recombination (By similarity)
XDD1_0813	ENOG4105DKQ	ROK family
XDD1_0814	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
XDD1_0815	ENOG4107QSI	ABC, transporter
XDD1_0816	ENOG4107QSI	ABC, transporter
XDD1_0817	ENOG4107QSI	ABC, transporter
XDD1_0819	ENOG4107QSI	ABC, transporter
XDD1_0821	ENOG4105EYH	Exonuclease
XDD1_0822	ENOG4107RH8	nuclease SbcCD subunit D
XDD1_0824	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
XDD1_0825	ENOG4105BZU	Histidine kinase
XDD1_0826	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
XDD1_0827	ENOG4105C8J	)-transporter
XDD1_0829	ENOG4105D3R	alkyl hydroperoxide reductase
XDD1_0831	ENOG4108ZYK	Acyl carrier protein phosphodiesterase
XDD1_0832	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
XDD1_0833	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
XDD1_0834	ENOG4105VIE	preprotein translocase, subunit YajC
XDD1_0836	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
XDD1_0837	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
XDD1_0838	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
XDD1_0839	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
XDD1_0840	ENOG4107YIM	Involved in the transcription termination process (By similarity)
XDD1_0841	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
XDD1_0842	ENOG4108ZAI	phosphatidylglycerophosphatase a
XDD1_0843	ENOG4108KN7	Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity)
XDD1_0847	ENOG4105C87	Aminotransferase class I and II
XDD1_0848	ENOG4105DFD	Na H antiporter
XDD1_0849	ENOG41060NJ	transcriptional regulator
XDD1_0857	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
XDD1_0858	ENOG4105CTB	Polyprenyl synthetase
XDD1_0860	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
XDD1_0861	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
XDD1_0862	ENOG4108VPT	UPF0234 protein
XDD1_0863	ENOG4107RDB	Major Facilitator
XDD1_0864	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
XDD1_0865	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
XDD1_0866	ENOG4105CCU	oxidase (Subunit III)
XDD1_0867	ENOG4105BZ9	Cytochrome C oxidase, subunit I
XDD1_0868	ENOG4105E2S	oxidase) subunit II
XDD1_0869	ENOG4108NFH	Sugar hydrolase
XDD1_0871	ENOG4105EYM	Major Facilitator superfamily
XDD1_0872	ENOG4105IEY	(LipO)protein
XDD1_0873	ENOG4105M85	Bola protein
XDD1_0876	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
XDD1_0877	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
XDD1_0878	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
XDD1_0880	ENOG4105EIN	peptidylprolyl cis-trans isomerase
XDD1_0882	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
XDD1_0883	ENOG4108TGP	Thioesterase superfamily protein
XDD1_0884	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
XDD1_0886	ENOG4108XM1	transcriptional regulator AsnC family
XDD1_0887	ENOG4105BZ1	(ABC) transporter
XDD1_0888	ENOG4105BZ1	(ABC) transporter
XDD1_0889	ENOG4108YZA	Nitrogen regulatory protein pii
XDD1_0890	ENOG4105BZU	Histidine kinase
XDD1_0891	ENOG4105C29	acyl-CoA thioesterase
XDD1_0894	ENOG4105KF5	hemolysin expression-modulating protein
XDD1_0895	ENOG4108UKR	Biofilm formation regulator YbaJ
XDD1_0897	ENOG4105BZS	acriflavin resistance protein
XDD1_0898	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
XDD1_0899	ENOG4108IG5	Transcriptional regulator
XDD1_0900	ENOG4105EGS	Mechanosensitive ion channel
XDD1_0901	ENOG4106428	Protein of unknown function (DUF2496)
XDD1_0903	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
XDD1_0904	ENOG4107QMP	dna polymerase iii subunits gamma and tau
XDD1_0905	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
XDD1_0907	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
XDD1_0908	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
XDD1_0910	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
XDD1_0912	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
XDD1_0913	ENOG4108QY5	Ferric enterobactin transport protein
XDD1_0914	ENOG4107RE1	Inosine-guanosine kinase
XDD1_0915	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
XDD1_0916	ENOG4105EU0	Major facilitator Superfamily
XDD1_0917	ENOG4105CGH	5'-nucleotidase
XDD1_0919	ENOG4108Z66	YbaK ebsC protein
XDD1_0920	ENOG4105MBR	gumn family
XDD1_0921	ENOG4105C59	p-type ATPase
XDD1_0922	ENOG4108Z6Z	Transcriptional regulator
XDD1_0923	ENOG4105G5H	Membrane
XDD1_0924	ENOG4107QX8	SPFH domain, Band 7 family protein
XDD1_0925	ENOG4107QR8	Thioredoxin
XDD1_0926	ENOG4105E1F	short-chain dehydrogenase reductase
XDD1_0927	ENOG4108UJV	acyl-CoA thioesterase i
XDD1_0928	ENOG4108I0Y	(ABC) transporter
XDD1_0929	ENOG4105CV6	ABC transporter, permease
XDD1_0931	ENOG4108R6K	riboflavin synthase, subunit alpha
XDD1_0934	ENOG4107SA8	fad-dependent pyridine nucleotide-disulfide oxidoreductase
XDD1_0936	ENOG4105KG1	l-proline 3-hydroxylase
XDD1_0937	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
XDD1_0938	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
XDD1_0939	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
XDD1_0940	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
XDD1_0942	ENOG4105C8N	cysteinyl-tRNA synthetase
XDD1_0944	ENOG4105WQ3	Rna-binding protein
XDD1_0945	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
XDD1_0954	ENOG4105VUH	addiction module killer protein
XDD1_0955	ENOG4105YES	addiction module antidote protein
XDD1_0959	ENOG4105CNA	YD repeat protein
XDD1_0969	ENOG4105CNA	YD repeat protein
XDD1_0972	ENOG4105CS6	Rhs element vgr protein
XDD1_0979	ENOG4105E9H	Lytic Murein transglycosylase
XDD1_0980	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
XDD1_0981	ENOG4105D1A	Methyltransferase
XDD1_0982	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
XDD1_0983	ENOG4108JDX	DNA polymerase iii, epsilon subunit
XDD1_0987	ENOG4105CV1	Transketolase (EC 2.2.1.1)
XDD1_0988	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
XDD1_0989	ENOG4105BZA	Phosphoglycerate kinase
XDD1_0990	ENOG4105D2N	Aldolase
XDD1_0992	ENOG4105DUX	Transporter
XDD1_0998	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
XDD1_0999	ENOG4105BZA	Phosphoglycerate kinase
XDD1_1000	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
XDD1_1005	ENOG4108JQ1	Dehydrogenase
XDD1_1010	ENOG4105CPQ	Dehydrogenase
XDD1_1011	ENOG4108JB8	alcohol dehydrogenase
XDD1_1012	ENOG4107UWN	reductase
XDD1_1013	ENOG4105EFA	4-hydroxyphenylacetate
XDD1_1017	ENOG41063TF	transcriptional regulator (AraC
XDD1_1021	ENOG4105C26	Dehydrogenase
XDD1_1023	ENOG4107THI	3,4-dihydroxyphenylacetate 2,3-dioxygenase
XDD1_1024	ENOG4105C26	Dehydrogenase
XDD1_1026	ENOG4105ERH	Fumarylacetoacetate hydrolase
XDD1_1028	ENOG4108V8F	Transcriptional regulator, MarR family
XDD1_1035	ENOG4105C26	Dehydrogenase
XDD1_1036	ENOG4108HRG	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity)
XDD1_1040	ENOG4107RUZ	Sss sodium solute transporter superfamily
XDD1_1041	ENOG4105D7K	pfkb domain protein
XDD1_1043	ENOG4105DH8	myo-inositol catabolism
XDD1_1048	ENOG4105ECQ	AraC Family Transcriptional Regulator
XDD1_1050	ENOG4105CHJ	isochorismatase hydrolase
XDD1_1054	ENOG4105HVQ	Regulatory factor of maltose metabolism
XDD1_1056	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
XDD1_1067	ENOG4105CDU	Replicative dna helicase
XDD1_1075	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
XDD1_1079	ENOG4108UUM	single-stranded DNA-binding protein
XDD1_1081	ENOG4105HVQ	Regulatory factor of maltose metabolism
XDD1_1100	ENOG4105TNG	K13735 adhesin invasin
XDD1_1101	ENOG4105DD7	kinase (PfkB family
XDD1_1112	ENOG4105CNA	YD repeat protein
XDD1_1114	ENOG4105CS6	Rhs element vgr protein
XDD1_1117	ENOG4105D5K	Hemolysin activator protein
XDD1_1119	ENOG41067NU	
XDD1_1128	ENOG4108X3P	Toxic component of a toxin-antitoxin (TA) module. Overexpression results in inhibition of growth in liquid cultures
XDD1_1133	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
XDD1_1134	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
XDD1_1135	ENOG4105CEN	a g-specific adenine glycosylase
XDD1_1136	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
XDD1_1137	ENOG41090ED	Protein with unknown function (DUF469)
XDD1_1138	ENOG4105CSV	Glutaminase
XDD1_1139	ENOG4105K33	Periplasmic Protein
XDD1_1142	ENOG4108V1U	phospholipid-binding protein
XDD1_1144	ENOG4105CC0	LysR family Transcriptional regulator
XDD1_1145	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
XDD1_1146	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
XDD1_1150	ENOG4105CSA	Coproporphyrinogen iii oxidase
XDD1_1151	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
XDD1_1152	ENOG4108VIA	integral membrane protein
XDD1_1153	ENOG4105II7	pyrroline-5-carboxylate reductase
XDD1_1154	ENOG4105DFA	alanine racemase domain protein
XDD1_1155	ENOG4105CZX	twitching motility protein
XDD1_1156	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
XDD1_1157	ENOG4108UJU	UPF0301 protein
XDD1_1158	ENOG4105D7Z	glutathione synthase
XDD1_1159	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
XDD1_1163	ENOG4105EJC	lysr family transcriptional regulator
XDD1_1164	ENOG4105RQF	LysR family Transcriptional regulator
XDD1_1165	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
XDD1_1166	ENOG4107QPN	acyl-Coa dehydrogenase
XDD1_1168	ENOG4105E7A	Glutamine amidotransferase
XDD1_1169	ENOG4105F7V	ErfK ybiS ycfS ynhG family protein
XDD1_1171	ENOG4105DWQ	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
XDD1_1172	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
XDD1_1173	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
XDD1_1174	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
XDD1_1175	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
XDD1_1177	ENOG4105CJ2	(LipO)protein
XDD1_1179	ENOG4108SF5	RNA Polymerase
XDD1_1180	ENOG4105X58	receptor
XDD1_1182	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
XDD1_1183	ENOG4105C26	Dehydrogenase
XDD1_1184	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
XDD1_1185	ENOG4105C94	Transporter
XDD1_1186	ENOG4107QF7	multi-drug
XDD1_1187	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
XDD1_1188	ENOG4105CIN	aminoacyl-histidine dipeptidase
XDD1_1189	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
XDD1_1190	ENOG4105V1F	Fermentation respiration switch protein
XDD1_1192	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
XDD1_1193	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
XDD1_1194	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
XDD1_1195	ENOG4105CEY	Amp-dependent synthetase and ligase
XDD1_1196	ENOG4108J8Q	Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity)
XDD1_1198	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
XDD1_1200	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
XDD1_1201	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
XDD1_1202	ENOG4105D9M	gamma-glutamylcysteine synthetase
XDD1_1204	ENOG4108JU6	CBS domain protein
XDD1_1205	ENOG4106KVJ	cytochrome C assembly protein
XDD1_1206	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
XDD1_1207	ENOG4105K5M	30s ribosomal protein S16
XDD1_1208	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
XDD1_1209	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
XDD1_1210	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
XDD1_1211	ENOG4106IQC	argininosuccinate lyase
XDD1_1213	ENOG4105D94	Major Facilitator Superfamily
XDD1_1216	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
XDD1_1217	ENOG4105EHE	chorismate mutase- prephenate dehydrogenase
XDD1_1218	ENOG4105CQC	Prephenate dehydratase
XDD1_1219	ENOG4108WPH	sigma 54 modulation protein ribosomal protein S30EA
XDD1_1220	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XDD1_1221	ENOG4105C34	Pseudouridine synthase
XDD1_1222	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
XDD1_1223	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
XDD1_1230	ENOG4105T42	(LipO)protein
XDD1_1231	ENOG4105JIM	Phosphatidylserine synthase
XDD1_1232	ENOG4105CD5	CoA-binding domain protein
XDD1_1233	ENOG4106IUH	DTW domain containing protein
XDD1_1234	ENOG4105EIB	trna rrna methyltransferase
XDD1_1236	ENOG4105CNM	Receptor
XDD1_1237	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
XDD1_1239	ENOG4105DQ5	transport system permease protein
XDD1_1240	ENOG4105TVJ	transport system, permease
XDD1_1241	ENOG4105E0A	ABC, transporter
XDD1_1242	ENOG4108819	ferric iron reductase
XDD1_1243	ENOG4105DY8	decarboxylase
XDD1_1244	ENOG4105F1Y	L-lysine 6-monooxygenase (NADPH)
XDD1_1245	ENOG4105DUU	IucA IucC family protein
XDD1_1247	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
XDD1_1248	ENOG4105CW7	secretion protein, HlyD family
XDD1_1249	ENOG4105NTK	Transcriptional repressor Mpra
XDD1_1251	ENOG4105ZED	uncharacterized protein ygaH
XDD1_1252	ENOG4108UMN	azlc family
XDD1_1254	ENOG4105GIJ	Glycine betaine
XDD1_1255	ENOG4108HQS	Glycine betaine
XDD1_1256	ENOG4108IJ7	Glycine betaine
XDD1_1259	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
XDD1_1260	ENOG4105VEQ	Cold shock protein
XDD1_1261	ENOG4107Z6W	Protein CrcB homolog
XDD1_1262	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
XDD1_1263	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
XDD1_1265	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
XDD1_1266	ENOG4108Z43	UPF0250 protein
XDD1_1267	ENOG4105DZ1	carboxypeptidase
XDD1_1270	ENOG4105CNI	cell division protein FtsW
XDD1_1271	ENOG4105CJN	penicillin-binding protein
XDD1_1272	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
XDD1_1273	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
XDD1_1275	ENOG4105DJF	DNA polymerase III, delta' subunit
XDD1_1276	ENOG4108U2H	Rare lipoprotein B
XDD1_1277	ENOG4105C8T	Leucyl-tRNA synthetase
XDD1_1278	ENOG4105CDA	abc transporter atp-binding protein
XDD1_1279	ENOG4105DRP	amino acid AbC transporter
XDD1_1280	ENOG4105EAD	ABC transporter
XDD1_1281	ENOG4107RP9	extracellular solute-binding protein, family 3
XDD1_1283	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
XDD1_1287	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
XDD1_1289	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
XDD1_1290	ENOG4108JU5	Magnesium and cobalt efflux protein
XDD1_1291	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
XDD1_1292	ENOG4105C9A	Phoh family
XDD1_1293	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
XDD1_1294	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
XDD1_1295	ENOG4105X5T	
XDD1_1296	ENOG4105E2R	ROK family
XDD1_1297	ENOG4105CE4	GlcNAc 6-P deacetylase
XDD1_1298	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
XDD1_1299	ENOG4105CI1	PTS System
XDD1_1300	ENOG4105CX6	glutaminyL-tRNA synthetase
XDD1_1302	ENOG41090R7	Ferric uptake
XDD1_1303	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
XDD1_1304	ENOG4105NNH	LexA regulated protein
XDD1_1307	ENOG4105FTV	AraC Family Transcriptional Regulator
XDD1_1308	ENOG4108JJA	ABC, transporter
XDD1_1309	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
XDD1_1312	ENOG4108RC6	RTX toxin
XDD1_1313	ENOG4105EUK	rtx toxin RtxA
XDD1_1316	ENOG4105DMQ	Methyltransferase
XDD1_1320	ENOG4105DMQ	Methyltransferase
XDD1_1321	ENOG4105EV9	Alpha Beta Hydrolase
XDD1_1323	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
XDD1_1326	ENOG4105C08	Histidine kinase
XDD1_1327	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
XDD1_1328	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
XDD1_1329	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
XDD1_1332	ENOG4105XIQ	Protein of unknown function (DUF2517)
XDD1_1333	ENOG4107QNR	UPF0135 protein
XDD1_1334	ENOG4105C2C	drug resistance transporter, Bcr CflA
XDD1_1336	ENOG4105BZN	citrate synthase
XDD1_1338	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
XDD1_1339	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
XDD1_1340	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
XDD1_1341	ENOG4105E33	succinate dehydrogenase
XDD1_1342	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
XDD1_1343	ENOG4105C7S	Dehydrogenase
XDD1_1344	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
XDD1_1345	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
XDD1_1346	ENOG4105C4M	(Ubiquinol oxidase) subunit I
XDD1_1347	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
XDD1_1349	ENOG4105KJB	cyd operon protein YbgE
XDD1_1350	ENOG4107YD3	Thioesterase
XDD1_1351	ENOG4105E02	MotA TolQ exbB proton channel
XDD1_1352	ENOG4105M8F	Biopolymer transport protein exbD tolR
XDD1_1353	ENOG4108Z82	Cell envelope integrity inner membrane protein TolA
XDD1_1354	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
XDD1_1355	ENOG4105KCK	Peptidoglycan-associated lipoprotein
XDD1_1356	ENOG4105UFD	tol-pal system protein YbgF
XDD1_1358	ENOG4106Z1T	Nicotinamide Mononucleotide Transporter
XDD1_1359	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
XDD1_1360	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
XDD1_1362	ENOG4105DKW	ABC transporter
XDD1_1363	ENOG410680R	Protein of unknown function (DUF2592)
XDD1_1365	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
XDD1_1366	ENOG4105E0C	molybdate abc transporter
XDD1_1367	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
XDD1_1368	ENOG4108K4B	hydrolase
XDD1_1370	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
XDD1_1377	ENOG4105CDU	Replicative dna helicase
XDD1_1384	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
XDD1_1388	ENOG4108UUM	single-stranded DNA-binding protein
XDD1_1390	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
XDD1_1391	ENOG4105HVQ	Regulatory factor of maltose metabolism
XDD1_1406	ENOG4108Q5F	Tetr family transcriptional regulator
XDD1_1408	ENOG4107QWP	ABC-2 type transporter
XDD1_1409	ENOG4107QWP	ABC-2 type transporter
XDD1_1410	ENOG4105CJ1	ABC, transporter
XDD1_1412	ENOG4107MVR	Transcriptional regulator
XDD1_1414	ENOG4105C1J	atp-dependent rna helicase
XDD1_1415	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
XDD1_1419	ENOG4105Y3U	Transglycosylase-associated protein
XDD1_1420	ENOG4105KHC	sulfurtransferase
XDD1_1422	ENOG4105DVT	helicase
XDD1_1423	ENOG4105C5H	ABC transporter
XDD1_1429	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
XDD1_1431	ENOG4107AQZ	Membrane
XDD1_1434	ENOG4105C5H	ABC transporter
XDD1_1435	ENOG4105D06	uba thif-type nad fad binding protein
XDD1_1436	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
XDD1_1437	ENOG4105CBP	Major Facilitator
XDD1_1438	ENOG4105EUJ	GTP cyclohydrolase i
XDD1_1439	ENOG4105DHF	Membrane
XDD1_1440	ENOG4107GZ4	SanA protein
XDD1_1441	ENOG4107R1I	NAD-dependent malic enzyme
XDD1_1442	ENOG4107T42	This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis (By similarity)
XDD1_1443	ENOG41067MG	lrgb family
XDD1_1444	ENOG4105VAW	lrga family
XDD1_1445	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
XDD1_1446	ENOG4105D1F	ATP-binding protein
XDD1_1447	ENOG4105DBI	uridine monophosphokinase
XDD1_1448	ENOG4105DHP	deoxycytidine triphosphate deaminase
XDD1_1449	ENOG4108GAE	asmA family
XDD1_1463	ENOG4105F9F	transposase
XDD1_1465	ENOG4105HFZ	Membrane
XDD1_1466	ENOG4108ZAF	Molybdopterin
XDD1_1467	ENOG4105M00	molybdopterin converting factor, subunit 1
XDD1_1468	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
XDD1_1469	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
XDD1_1470	ENOG4105CHW	UPF0052 protein
XDD1_1471	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
XDD1_1472	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
XDD1_1473	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
XDD1_1474	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
XDD1_1475	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
XDD1_1482	ENOG4108WC9	type VI secretion system effector, hcp1 family
XDD1_1491	ENOG4105CNA	YD repeat protein
XDD1_1494	ENOG41067QW	Transcriptional regulator
XDD1_1495	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
XDD1_1509	ENOG4105DD7	kinase (PfkB family
XDD1_1517	ENOG4105EE5	Membrane protein terC
XDD1_1518	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
XDD1_1520	ENOG4105C0A	alcohol dehydrogenase
XDD1_1521	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
XDD1_1522	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
XDD1_1523	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
XDD1_1524	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
XDD1_1525	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
XDD1_1526	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
XDD1_1527	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
XDD1_1528	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
XDD1_1530	ENOG4108535	NAD dependent epimerase/dehydratase family
XDD1_1531	ENOG4108TGY	Glutathione S-transferase
XDD1_1532	ENOG4105DZ1	carboxypeptidase
XDD1_1533	ENOG4105C44	Serine transporter
XDD1_1534	ENOG4105D1E	Undecaprenyl pyrophosphate phosphatase
XDD1_1535	ENOG41090BQ	Glutaredoxin
XDD1_1537	ENOG4105X20	member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress
XDD1_1538	ENOG4108RMJ	sensory transduction regulator
XDD1_1539	ENOG4107SFS	Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA (By similarity)
XDD1_1540	ENOG4105DMR	ABC, transporter
XDD1_1541	ENOG4105GBT	ABC transporter
XDD1_1542	ENOG4106PMH	Extracellular solute-binding protein family 3
XDD1_1543	ENOG4105E5Z	arginine transporter ATP-binding subunit
XDD1_1544	ENOG4105DWU	Membrane
XDD1_1546	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
XDD1_1547	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
XDD1_1548	ENOG4105VEQ	Cold shock protein
XDD1_1549	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
XDD1_1550	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
XDD1_1551	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
XDD1_1552	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
XDD1_1553	ENOG4108JJ8	(ABC) transporter
XDD1_1554	ENOG4108JJ9	ABC, transporter
XDD1_1555	ENOG4105C3M	thioredoxin reductase
XDD1_1557	ENOG4105EW9	transcriptional regulator AsnC family
XDD1_1558	ENOG4105CNU	cell division protein FtsK
XDD1_1559	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
XDD1_1560	ENOG4105D1H	recombination factor protein RarA
XDD1_1561	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
XDD1_1565	ENOG4105F1A	Pyruvate formate-lyase
XDD1_1566	ENOG4105C6N	Formate acetyltransferase
XDD1_1567	ENOG4105TMB	Formate nitrite transporter
XDD1_1568	ENOG4105DDY	UPF0142 protein ycaO
XDD1_1569	ENOG4105HDK	L-asparaginase
XDD1_1570	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
XDD1_1571	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
XDD1_1572	ENOG4105CAT	Cytidine monophosphate kinase
XDD1_1574	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
XDD1_1576	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
XDD1_1577	ENOG4105BZ1	(ABC) transporter
XDD1_1578	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
XDD1_1579	ENOG4105W49	UPF0434 protein
XDD1_1580	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
XDD1_1581	ENOG4107S90	membrAne
XDD1_1582	ENOG4106371	Methyltransferase
XDD1_1583	ENOG4105GHU	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity (By similarity)
XDD1_1584	ENOG4105DAH	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity)
XDD1_1585	ENOG4105DUC	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division (By similarity)
XDD1_1586	ENOG4105F0S	class B acid phosphatase
XDD1_1587	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
XDD1_1588	ENOG4105EAQ	(twin-arginine translocation) pathway signal
XDD1_1589	ENOG4105C5X	domain protein
XDD1_1590	ENOG4105CGF	Aromatic amino acid aminotransferase
XDD1_1591	ENOG4105FCK	Membrane
XDD1_1592	ENOG4105C5S	asparaginyl-tRNA synthetase
XDD1_1593	ENOG4107RH7	Nicotinate phosphoribosyltransferase
XDD1_1595	ENOG4105CD8	aminopeptidase N
XDD1_1596	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
XDD1_1597	ENOG4108T7E	Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity)
XDD1_1598	ENOG4105QVC	MOSC domain-containing protein
XDD1_1599	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
XDD1_1600	ENOG4105C5H	ABC transporter
XDD1_1601	ENOG4105F1S	paraquat-inducible protein a
XDD1_1602	ENOG4105DY2	Paraquat-inducible protein b
XDD1_1603	ENOG4108Q2G	(LipO)protein
XDD1_1604	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
XDD1_1605	ENOG4105DAN	ATP-dependent protease
XDD1_1606	ENOG4108R9Q	Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain (By similarity)
XDD1_1609	ENOG4108ZD2	Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division (By similarity)
XDD1_1618	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
XDD1_1634	ENOG4105EM2	membrane
XDD1_1635	ENOG41088T4	Helicase IV
XDD1_1636	ENOG4105K4P	CoA-binding domain protein
XDD1_1637	ENOG4105GSS	Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress (By similarity)
XDD1_1638	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
XDD1_1639	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
XDD1_1648	ENOG4105CAR	Terminase, large subunit
XDD1_1649	ENOG4105HVQ	Regulatory factor of maltose metabolism
XDD1_1655	ENOG4105CHU	acetyl-coa acetyltransferase
XDD1_1656	ENOG4107SET	aldo keto reductase
XDD1_1661	ENOG4107S1E	Beta-lactamase
XDD1_1670	ENOG4105SKE	transcriptional Regulator LysR family
XDD1_1671	ENOG4108IPJ	Membrane
XDD1_1674	ENOG4105WH1	Two component transcriptional regulator luxr family
XDD1_1675	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
XDD1_1676	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
XDD1_1683	ENOG4108WC9	type VI secretion system effector, hcp1 family
XDD1_1694	ENOG4105CAR	Terminase, large subunit
XDD1_1695	ENOG4105HVQ	Regulatory factor of maltose metabolism
XDD1_1699	ENOG4108Z12	YiaAB two helix domain-containing protein
XDD1_1707	ENOG4105MJ9	esterase
XDD1_1709	ENOG4105DMF	Dehydrogenase
XDD1_1711	ENOG4105JAB	phenazine biosynthesis protein, phzf family
XDD1_1717	ENOG4105D1S	lipid A biosynthesis
XDD1_1719	ENOG4108K0D	peptidase, M48
XDD1_1722	ENOG4105CXY	transporter
XDD1_1723	ENOG4108KX4	response regulator
XDD1_1724	ENOG4105BZU	Histidine kinase
XDD1_1725	ENOG4105CXY	transporter
XDD1_1726	ENOG4105DHI	Methyltransferase
XDD1_1727	ENOG4108UI1	Probably functions as a manganese efflux pump (By similarity)
XDD1_1728	ENOG4108NK4	UPF0266 membrane protein
XDD1_1729	ENOG4105F3R	pts system mannose fructose sorbose family iid
XDD1_1730	ENOG4105ETZ	PTS System
XDD1_1731	ENOG4108EQA	pts system
XDD1_1732	ENOG4105EJQ	L-serine dehydratase
XDD1_1733	ENOG4105P8F	nudix hydrolase
XDD1_1734	ENOG4105CRQ	synthase (Component I)
XDD1_1735	ENOG4105X5C	UPF0181 protein
XDD1_1736	ENOG4105VBS	Inherit from NOG: Secreted protein
XDD1_1738	ENOG4105MPK	DNA polymerase III subunit theta
XDD1_1742	ENOG41090A1	ferritin
XDD1_1743	ENOG4105FXM	Copper resistance protein
XDD1_1744	ENOG4108PNC	copper resistance
XDD1_1745	ENOG4105NKT	exported protein
XDD1_1746	ENOG4108ZGC	gaf domain protein
XDD1_1747	ENOG41073DY	may be a structural element that influences the osmotic activation of ProP at a post-translational level (By similarity)
XDD1_1748	ENOG4105CN1	protease
XDD1_1749	ENOG4105D0M	Protease HtpX homolog
XDD1_1750	ENOG4108ETY	sodium dicarboxylate symporter
XDD1_1751	ENOG4107K5X	Membrane-bound metal-dependent hydrolase
XDD1_1755	ENOG4107PN8	YfeABCD locus regulator
XDD1_1756	ENOG4105FGM	Fructosamine kinase
XDD1_1757	ENOG4105CC5	ABC transporter
XDD1_1758	ENOG4105CC5	ABC transporter
XDD1_1759	ENOG4105DIK	(ABC) transporter
XDD1_1760	ENOG4105DSE	periplasmic solute binding protein
XDD1_1761	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
XDD1_1763	ENOG4105TNG	K13735 adhesin invasin
XDD1_1772	ENOG4105C22	threonyL-tRNA synthetase
XDD1_1773	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
XDD1_1774	ENOG41082NX	50s ribosomal protein l35
XDD1_1777	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
XDD1_1778	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
XDD1_1779	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
XDD1_1780	ENOG4105CKK	Glycosyl transferase, family 2
XDD1_1781	ENOG4108JU4	Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
XDD1_1782	ENOG4105F73	Catalyzes the deformylation of 4-deoxy-4-formamido-L- arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
XDD1_1783	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
XDD1_1785	ENOG4105PE8	Translocates 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane (By similarity)
XDD1_1786	ENOG4108QBX	(LipO)protein
XDD1_1789	ENOG4105F9F	transposase
XDD1_1792	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
XDD1_1796	ENOG4105C0W	non-ribosomal peptide synthetase
XDD1_1808	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
XDD1_1809	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
XDD1_1810	ENOG4105EHG	Permease protein
XDD1_1811	ENOG4107R4I	Periplasmic binding protein
XDD1_1812	ENOG4106QJH	hemin transport protein
XDD1_1813	ENOG4107ENK	receptor
XDD1_1814	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
XDD1_1815	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
XDD1_1820	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
XDD1_1821	ENOG4105TIV	Cryptic phage CTXphi transcriptional repressor RstR
XDD1_1826	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
XDD1_1834	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
XDD1_1843	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
XDD1_1844	ENOG4105IPI	Membrane
XDD1_1845	ENOG4105CQB	FAD linked oxidase domain protein
XDD1_1846	ENOG4105KA0	thioesterase Superfamily protein
XDD1_1848	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
XDD1_1849	ENOG4105KMX	major outer membrane lipoprotein
XDD1_1850	ENOG4105CA9	Pyruvate kinase
XDD1_1851	ENOG4107QI1	Mate efflux family protein
XDD1_1852	ENOG4108R6K	riboflavin synthase, subunit alpha
XDD1_1853	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
XDD1_1855	ENOG4105CZQ	inner membrane transport protein YdhC
XDD1_1856	ENOG4105F52	Transcriptional regulator
XDD1_1857	ENOG4105ETE	Transcriptional regulator (LacI family
XDD1_1858	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
XDD1_1859	ENOG4105M2J	Glutaredoxin
XDD1_1860	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
XDD1_1861	ENOG4108UYE	Lactoylglutathione lyase
XDD1_1862	ENOG4105XZD	Fe-S protein
XDD1_1864	ENOG4108XTF	Outer Membrane Lipoprotein
XDD1_1865	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
XDD1_1866	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
XDD1_1867	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
XDD1_1868	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
XDD1_1869	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
XDD1_1870	ENOG4108JQ2	peptide transport system atp-binding protein
XDD1_1871	ENOG4108JQ3	Peptide ABC transporter ATP-binding protein
XDD1_1872	ENOG4108EU3	peptide transport system, permease
XDD1_1873	ENOG4108I5W	peptide transport system, permease protein
XDD1_1874	ENOG4108HIY	periplasmic
XDD1_1875	ENOG4105E51	psp operon transcriptional activator
XDD1_1876	ENOG41087YS	Phage shock protein A
XDD1_1877	ENOG4105YYT	phage shock protein B
XDD1_1878	ENOG4105FM1	phage shock protein C
XDD1_1879	ENOG4105CM6	amino acid regulated cytosolic protein
XDD1_1884	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
XDD1_1894	ENOG4106VK6	Flagellar motor protein
XDD1_1903	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
XDD1_1904	ENOG4107RX3	Mg2 transporter protein cora family protein
XDD1_1905	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
XDD1_1910	ENOG410814C	multidrug resistance protein
XDD1_1912	ENOG4105CR8	Transcriptional regulator
XDD1_1913	ENOG4105F27	Major Facilitator
XDD1_1914	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
XDD1_1920	ENOG4105C26	Dehydrogenase
XDD1_1924	ENOG4108JPW	Aminotransferase
XDD1_1926	ENOG4105KAF	membrAne
XDD1_1927	ENOG4105CJP	fad dependent oxidoreductase
XDD1_1928	ENOG4105EI3	2-dehydro-3-deoxygalactonokinase EC 2.7.1.58
XDD1_1929	ENOG4108RTU	Aldolase
XDD1_1930	ENOG4105CXK	mandelate racemase muconate lactonizing
XDD1_1931	ENOG4105DJB	Major Facilitator Superfamily
XDD1_1936	ENOG4105E5W	Transporter
XDD1_1940	ENOG4105D9N	nucleoside
XDD1_1941	ENOG4108U51	Universal stress protein
XDD1_1942	ENOG4108RW8	Universal stress protein F
XDD1_1944	ENOG4105RWS	endonuclease I
XDD1_1960	ENOG4108JPW	Aminotransferase
XDD1_1963	ENOG4105DUU	IucA IucC family protein
XDD1_1964	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
XDD1_1965	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
XDD1_1966	ENOG4105DUU	IucA IucC family protein
XDD1_1968	ENOG4105DJU	Siderophore biosynthesis protein
XDD1_1969	ENOG4108MES	Periplasmic binding protein
XDD1_1970	ENOG4105DQ5	transport system permease protein
XDD1_1971	ENOG4108IHU	transport system permease protein
XDD1_1972	ENOG4105E0A	ABC, transporter
XDD1_1974	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
XDD1_1975	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
XDD1_1976	ENOG4105C4M	(Ubiquinol oxidase) subunit I
XDD1_1979	ENOG41082JN	Transcriptional regulator
XDD1_1982	ENOG4105R8A	Heat shock protein
XDD1_1983	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
XDD1_1986	ENOG4105D5U	fad dependent oxidoreductase
XDD1_1993	ENOG4105NF4	modulator of drug activity
XDD1_1994	ENOG4105CF7	AraC family transcriptional regulator
XDD1_1995	ENOG4105C3G	gtp-binding protein
XDD1_1996	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
XDD1_2000	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
XDD1_2001	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
XDD1_2002	ENOG4105C1U	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
XDD1_2003	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
XDD1_2004	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
XDD1_2005	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
XDD1_2006	ENOG41063JG	Transcriptional regulator
XDD1_2007	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
XDD1_2008	ENOG4105CHH	sulfate transporter
XDD1_2009	ENOG41077RS	Phosphatase
XDD1_2010	ENOG4105E8V	Alpha Beta Hydrolase Fold protein
XDD1_2011	ENOG4108UMZ	Cdp-alcohol phosphatidyltransferase
XDD1_2012	ENOG4105D29	Helix-turn-helix type 11 domain protein
XDD1_2018	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
XDD1_2019	ENOG4107XHZ	cytoplasmic chaperone TorD family protein
XDD1_2020	ENOG4108WC9	type VI secretion system effector, hcp1 family
XDD1_2025	ENOG4105F3T	(LipO)protein
XDD1_2026	ENOG4105EV4	Multidrug resistance protein mdtH
XDD1_2027	ENOG4105D9U	N-acetyltransferase
XDD1_2030	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
XDD1_2040	ENOG4106VK6	Flagellar motor protein
XDD1_2052	ENOG4105CJR	Integral membrane protein (MviN
XDD1_2054	ENOG4105C75	arginyL-tRNA synthetase
XDD1_2056	ENOG4106N3A	copper homeostasis protein cutc
XDD1_2057	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
XDD1_2058	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
XDD1_2059	ENOG4105WJG	Glutathione
XDD1_2061	ENOG4105C9M	aspartyl-trna synthetase
XDD1_2062	ENOG4108TIT	dATP pyrophosphohydrolase
XDD1_2063	ENOG4105CDY	transcriptional regulatory protein
XDD1_2064	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
XDD1_2065	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
XDD1_2066	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
XDD1_2069	ENOG4105FAV	ABC, transporter
XDD1_2070	ENOG4105FDK	ABC transporter
XDD1_2071	ENOG4105NXV	High-affinity zinc uptake system protein
XDD1_2072	ENOG4105DR5	peptidase
XDD1_2073	ENOG4105NWR	lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase
XDD1_2074	ENOG4105CA9	Pyruvate kinase
XDD1_2075	ENOG4106KNT	transcriptional regulator
XDD1_2077	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
XDD1_2078	ENOG41090TI	Catalyzes the excretion of spermidine (By similarity)
XDD1_2079	ENOG4108ZBZ	Catalyzes the excretion of spermidine (By similarity)
XDD1_2080	ENOG4105M4H	endoribonuclease L-psp
XDD1_2081	ENOG4105DVT	helicase
XDD1_2082	ENOG41072GX	Peptidase M22 Glycoprotease
XDD1_2083	ENOG4105Y4Z	Outer Membrane Lipoprotein
XDD1_2084	ENOG4105CEY	Amp-dependent synthetase and ligase
XDD1_2085	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
XDD1_2086	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
XDD1_2087	ENOG4107QMS	site-determining protein
XDD1_2088	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
XDD1_2089	ENOG4105VNG	YcgL domain-containing protein
XDD1_2090	ENOG4105CVE	Lytic murein transglycosylase
XDD1_2091	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
XDD1_2092	ENOG4108ZZ3	UPF0260 protein
XDD1_2096	ENOG4105C5I	Dehydrogenase
XDD1_2097	ENOG4107H52	Dicarboxylate transport
XDD1_2098	ENOG410689M	(LipO)protein
XDD1_2099	ENOG4105WXT	Conserved Protein
XDD1_2100	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
XDD1_2101	ENOG4105CQ7	ATP-dependent helicase
XDD1_2104	ENOG4105CW0	outer membrane usher protein
XDD1_2105	ENOG4108VCD	Chaperone
XDD1_2107	ENOG4105D5Q	Arginine ornithine antiporter
XDD1_2109	ENOG4105C5D	exported protein
XDD1_2110	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
XDD1_2111	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
XDD1_2114	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
XDD1_2122	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
XDD1_2129	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
XDD1_2136	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
XDD1_2138	ENOG4105CCF	Lysine exporter protein (Lyse ygga)
XDD1_2140	ENOG4107XZQ	multidrug resistance protein
XDD1_2149	ENOG4108KTG	Membrane protein, drug metabolite transporter
XDD1_2151	ENOG4107RNH	Outer membrane receptor FepA
XDD1_2154	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
XDD1_2160	ENOG4105RHY	Pfam:UPF0157
XDD1_2161	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
XDD1_2162	ENOG4105FQP	Beta-lactamase
XDD1_2165	ENOG4106AXJ	AraC family transcriptional regulator
XDD1_2167	ENOG41071I4	Phosphatidylserine decarboxylase proenzyme
XDD1_2169	ENOG4105BZ1	(ABC) transporter
XDD1_2170	ENOG4105EMU	Dehydrogenase
XDD1_2171	ENOG4105M5Q	UPF0482 protein
XDD1_2173	ENOG4105EWW	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
XDD1_2177	ENOG4105D94	Major Facilitator Superfamily
XDD1_2180	ENOG4105C9Q	fumarate hydratase class II
XDD1_2181	ENOG4105EIP	mannose-6-phosphate isomerase
XDD1_2182	ENOG4106J39	exported protein
XDD1_2183	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
XDD1_2184	ENOG4105DHU	Bile acid
XDD1_2185	ENOG4105D9R	oxidoreductase
XDD1_2186	ENOG4105M9B	inner membrane protein ydgK
XDD1_2187	ENOG4105DGN	Electron transport complex
XDD1_2189	ENOG4107QTR	Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity)
XDD1_2191	ENOG4108UQQ	Electron transport complex
XDD1_2194	ENOG4105CSM	endonuclease III
XDD1_2195	ENOG4108IEC	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction (By similarity)
XDD1_2197	ENOG4108ZJT	translation initiation factor, Sui1
XDD1_2198	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
XDD1_2199	ENOG4105CFV	Tetratricopeptide repeat protein
XDD1_2200	ENOG4105Q4A	inner membrane protein yciS
XDD1_2203	ENOG4107QM5	aconitate hydratase
XDD1_2206	ENOG4107R11	Transcriptional regulator
XDD1_2207	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
XDD1_2208	ENOG4105RKX	Protein of unknown function (DUF2498)
XDD1_2209	ENOG4105ERU	peptidase
XDD1_2211	ENOG4105UBK	short-chain dehydrogenase reductase
XDD1_2212	ENOG4105FE9	pseudouridine synthase
XDD1_2213	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
XDD1_2214	ENOG4105DB7	PHP domain protein
XDD1_2215	ENOG4105CRQ	synthase (Component I)
XDD1_2217	ENOG4107QYG	anthranilate phosphoribosyltransferase
XDD1_2218	ENOG4105DK0	Indole-3-glycerol phosphate synthase
XDD1_2219	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
XDD1_2220	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
XDD1_2221	ENOG4105EIF	outer membrane protein W
XDD1_2222	ENOG4108S3I	UPF0259 membrane protein
XDD1_2224	ENOG4107835	probably involved in intracellular septation (By similarity)
XDD1_2225	ENOG4105NAU	thioesterase Superfamily protein
XDD1_2226	ENOG410822N	TonB family
XDD1_2228	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
XDD1_2229	ENOG4108W5H	UPF0263 protein
XDD1_2230	ENOG4108JQ7	(ABC) transporter
XDD1_2231	ENOG4105C3U	ABC transporter
XDD1_2232	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
XDD1_2233	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
XDD1_2234	ENOG4107QSI	ABC, transporter
XDD1_2235	ENOG4107QSI	ABC, transporter
XDD1_2236	ENOG4108EKI	Dehydrogenase
XDD1_2237	ENOG4107104	thymidine kinase
XDD1_2240	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
XDD1_2241	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
XDD1_2242	ENOG4105K5B	UPF0225 protein
XDD1_2243	ENOG4105CIY	formyltetrahydrofolate deformylase
XDD1_2246	ENOG4105CGK	Exodeoxyribonuclease III
XDD1_2247	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
XDD1_2248	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
XDD1_2249	ENOG41069NU	Nitroreductase
XDD1_2250	ENOG4105D07	Signal peptide peptidase, SppA
XDD1_2251	ENOG4105HDK	L-asparaginase
XDD1_2252	ENOG4105VUT	cytoplasmic protein
XDD1_2255	ENOG4105DSB	aldose 1-epimerase
XDD1_2256	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
XDD1_2257	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
XDD1_2258	ENOG4105C05	Multifunctional regulator of fatty acid metabolism (By similarity)
XDD1_2259	ENOG4105DKR	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
XDD1_2260	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
XDD1_2268	ENOG4105E5W	Transporter
XDD1_2274	ENOG4105D5Q	Arginine ornithine antiporter
XDD1_2275	ENOG4105CXN	decarboxylase
XDD1_2284	ENOG4105DY8	decarboxylase
XDD1_2289	ENOG4105DY8	decarboxylase
XDD1_2290	ENOG4105FBW	Monooxygenase
XDD1_2293	ENOG4105IBP	Cyclic peptide transporter
XDD1_2294	ENOG4105CK7	Sodium proline symporter
XDD1_2296	ENOG4105C26	Dehydrogenase
XDD1_2297	ENOG4108M9K	flagella biosynthesis protein FliZ
XDD1_2298	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
XDD1_2301	ENOG4105DTS	flagellar hook-associated
XDD1_2302	ENOG4105MQ3	flagellar protein FliS
XDD1_2303	ENOG4105YXP	it directly binds FlhC, thus inhibiting the binding of the FlhC FlhD complex to class 2 promoters, resulting in decreased expression of class 2 flagellar operons. As a chaperone, effects FliD transition to the membrane by preventing its premature polymerization, and by directing it to the export apparatus (By similarity)
XDD1_2308	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
XDD1_2310	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
XDD1_2311	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
XDD1_2312	ENOG41090PJ	Flagellar assembly protein
XDD1_2313	ENOG4108JIR	Flagellum-specific ATP synthase
XDD1_2314	ENOG4105GSA	Flagellar export protein flij
XDD1_2315	ENOG4105WF4	Flagellar hook-length control protein
XDD1_2317	ENOG4107ZI8	flagellar basal body-associated protein flil
XDD1_2318	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
XDD1_2319	ENOG4105DD5	Flagellar motor switch protein
XDD1_2321	ENOG4105CN7	Flagellar biosynthetic protein FliP
XDD1_2322	ENOG4105VS8	Flagellar biosynthetic protein fliq
XDD1_2323	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
XDD1_2324	ENOG4105CHR	reductase
XDD1_2328	ENOG4105VT3	DNA binding domain protein, excisionase family
XDD1_2329	ENOG4105DTJ	flagellar hook-associated protein
XDD1_2330	ENOG4105E1Q	flagellar hook-associated protein
XDD1_2331	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
XDD1_2332	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
XDD1_2333	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
XDD1_2334	ENOG4105CGA	flagellar basal-body rod protein FlgG
XDD1_2335	ENOG4108KPB	Flagellar basal-body rod protein FlgF
XDD1_2336	ENOG4105BZE	flagellar hook protein, FlgE
XDD1_2337	ENOG4105W00	Flagellar hook capping protein
XDD1_2338	ENOG4108ZC9	flagellar basal-body rod protein flgc
XDD1_2339	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
XDD1_2340	ENOG4105CKS	Flagella basal body P-ring formation protein flgA
XDD1_2341	ENOG4105M9M	anti-sigma28 factor FlgM
XDD1_2342	ENOG4105QVD	Flagella synthesis protein FlgN
XDD1_2344	ENOG41074HU	Fimbrial adhesin
XDD1_2345	ENOG4105CW0	outer membrane usher protein
XDD1_2346	ENOG4108VCD	Chaperone
XDD1_2352	ENOG4105D7B	Flagellar biosynthesis protein flha
XDD1_2353	ENOG4105D00	flagellar biosynthetic protein flhB
XDD1_2354	ENOG4105BZG	amino acid carrier protein
XDD1_2355	ENOG4108C33	Resolvase
XDD1_2359	ENOG4105CS6	Rhs element vgr protein
XDD1_2367	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
XDD1_2368	ENOG4108VYJ	response regulator receiver protein
XDD1_2369	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
XDD1_2370	ENOG4105BZU	Histidine kinase
XDD1_2371	ENOG4105C8Q	Methyl-accepting chemotaxis
XDD1_2372	ENOG4105C8Q	Methyl-accepting chemotaxis
XDD1_2373	ENOG4108V3W	Chemotaxis protein, CheW
XDD1_2374	ENOG4105CBS	Chea signal transduction histidine kinase
XDD1_2375	ENOG4105ER2	Ompa motb domain protein
XDD1_2376	ENOG4107RD7	Flagellar Motor Protein, MotA
XDD1_2377	ENOG4106CIA	Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region
XDD1_2378	ENOG4105GEH	Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways (By similarity)
XDD1_2379	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
XDD1_2380	ENOG4105KT7	mgtC SapB transporter
XDD1_2381	ENOG4105VEQ	Cold shock protein
XDD1_2382	ENOG4105GSJ	Inner membrane protein ylaC
XDD1_2384	ENOG4105EKE	dihydroorotase
XDD1_2385	ENOG4105PVA	Biofilm formation regulatory protein BssS
XDD1_2387	ENOG4105C72	UPF0176 protein
XDD1_2392	ENOG4106MMI	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
XDD1_2393	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
XDD1_2394	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
XDD1_2395	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
XDD1_2401	ENOG4105CUG	Oligopeptidase b
XDD1_2405	ENOG4105C6K	Malic enzyme
XDD1_2408	ENOG4105WH1	Two component transcriptional regulator luxr family
XDD1_2409	ENOG4105KUZ	arsenate reductase
XDD1_2410	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
XDD1_2412	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
XDD1_2413	ENOG4108VMM	UPF0756 membrane protein
XDD1_2414	ENOG4105C8V	SAICAR synthetase
XDD1_2415	ENOG4107EG0	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
XDD1_2416	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
XDD1_2417	ENOG4105RH4	Glycine cleavage system transcriptional repressor
XDD1_2420	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
XDD1_2421	ENOG4105C02	permease
XDD1_2422	ENOG4105ERG	peptidase m48, ste24p
XDD1_2423	ENOG4105K89	arsenate reductase
XDD1_2424	ENOG4108KZ1	Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA (By similarity)
XDD1_2426	ENOG4105C2W	permease
XDD1_2427	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
XDD1_2428	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
XDD1_2429	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
XDD1_2430	ENOG4108MK9	spermidine N(1)-acetyltransferase
XDD1_2431	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
XDD1_2432	ENOG4105C9X	ppx gppa phosphatase
XDD1_2433	ENOG41062G3	Protein of unknown function (DUF2633)
XDD1_2434	ENOG4105CJW	magnesium transporter
XDD1_2438	ENOG4105X17	23-dihydro-2,3-dihydroxybenzoate dehydrogenase
XDD1_2441	ENOG4105FDK	ABC transporter
XDD1_2442	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
XDD1_2446	ENOG4105E18	UPF0276 protein
XDD1_2454	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
XDD1_2455	ENOG4105BZS	acriflavin resistance protein
XDD1_2456	ENOG4105BZS	acriflavin resistance protein
XDD1_2457	ENOG4105EB3	Histidine kinase
XDD1_2458	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
XDD1_2459	ENOG4105F27	Major Facilitator
XDD1_2460	ENOG4105KWI	UPF0339 protein
XDD1_2461	ENOG4105CFP	Peptidase U32
XDD1_2462	ENOG4105EIE	fructose-bisphosphate aldolase
XDD1_2463	ENOG4105DWF	phosphomethylpyrimidine kinase
XDD1_2464	ENOG4105VEQ	Cold shock protein
XDD1_2465	ENOG4105C85	amino acid
XDD1_2467	ENOG4105UEI	Transcriptional Regulator AraC Family
XDD1_2468	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
XDD1_2469	ENOG4105BZG	amino acid carrier protein
XDD1_2473	ENOG4108HMX	isocitrate dehydrogenase (NADP)
XDD1_2474	ENOG4108R99	pseudouridine synthase
XDD1_2476	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
XDD1_2477	ENOG41075W9	High frequency lysogenization protein HflD homolog
XDD1_2478	ENOG4107QTF	adenylosuccinate lyase
XDD1_2480	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
XDD1_2482	ENOG4105EZE	Cupin 4 family protein
XDD1_2484	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
XDD1_2485	ENOG4105D60	lipoprotein releasing system transmembrane protein
XDD1_2486	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
XDD1_2487	ENOG4105D60	lipoprotein releasing system transmembrane protein
XDD1_2488	ENOG4108JA2	transcriptioN-repair coupling factor
XDD1_2491	ENOG4105CEP	NADH dehydrogenase
XDD1_2492	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
XDD1_2494	ENOG4108WEF	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b) (By similarity)
XDD1_2495	ENOG4105K59	histidine triad (HIT) protein
XDD1_2496	ENOG4105F8V	Hydrolase, tatD family
XDD1_2497	ENOG4107QRG	dna polymerase iii
XDD1_2498	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
XDD1_2499	ENOG4105HHA	aminodeoxychorismate lyase
XDD1_2500	ENOG4105YAZ	4-amino-4-deoxychorismate lyase
XDD1_2501	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
XDD1_2502	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
XDD1_2503	ENOG4105CHR	reductase
XDD1_2504	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
XDD1_2505	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
XDD1_2506	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
XDD1_2507	ENOG4105VGS	50s ribosomal protein l32
XDD1_2508	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
XDD1_2509	ENOG4108UHJ	MAF-like protein
XDD1_2510	ENOG4105EI2	Pseudouridine synthase
XDD1_2511	ENOG4107QQB	Ribonuclease E
XDD1_2513	ENOG41090HJ	UPF0265 protein
XDD1_2514	ENOG4105CJB	Exodeoxyribonuclease I
XDD1_2515	ENOG4105CXG	d-lactate dehydrogenase
XDD1_2516	ENOG4105CUB	amino acid
XDD1_2517	ENOG4105D05	Receptor
XDD1_2518	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
XDD1_2519	ENOG4105EHG	Permease protein
XDD1_2521	ENOG4108IQI	permease
XDD1_2522	ENOG4105DUM	transcriptional regulator, lysR family
XDD1_2524	ENOG4105HMI	Membrane
XDD1_2525	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
XDD1_2526	ENOG4105DE4	1-phosphofructokinase
XDD1_2527	ENOG4105E09	nadh pyrophosphatase
XDD1_2529	ENOG4105FUQ	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
XDD1_2533	ENOG41076MN	Phosphoesterase, PA-phosphatase related
XDD1_2535	ENOG4107TT5	NLP P60 protein
XDD1_2536	ENOG4105HG6	
XDD1_2537	ENOG4105C2C	drug resistance transporter, Bcr CflA
XDD1_2538	ENOG4105I08	Pseudouridine synthase
XDD1_2539	ENOG4105CFI	type iii restriction protein res subunit
XDD1_2540	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
XDD1_2541	ENOG4106V8H	Nucleoid-associated protein
XDD1_2542	ENOG4105PAN	UPF0352 protein
XDD1_2543	ENOG4105E68	Sulfatase
XDD1_2551	ENOG4108M1A	Chitin-binding protein
XDD1_2552	ENOG4105HB7	Glyoxalase Bleomycin resistance protein (Dioxygenase
XDD1_2555	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
XDD1_2556	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
XDD1_2557	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
XDD1_2558	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
XDD1_2559	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
XDD1_2560	ENOG4105BZU	Histidine kinase
XDD1_2561	ENOG41068CG	regulatoR
XDD1_2562	ENOG4105E3G	Phosphotransfer intermediate protein in two-component regulatory system with RcsBC
XDD1_2564	ENOG4105E0U	tyrosine-specific transport protein
XDD1_2565	ENOG4108UII	YfaZ family
XDD1_2566	ENOG4105CEY	Amp-dependent synthetase and ligase
XDD1_2567	ENOG4105DNI	Converts SHCHC to OSB (By similarity)
XDD1_2568	ENOG4108IPT	Naphthoate synthase
XDD1_2569	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
XDD1_2570	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
XDD1_2571	ENOG4105E4F	Isochorismate synthase
XDD1_2572	ENOG4108TUY	outer membrane protein PgaA
XDD1_2573	ENOG4107BJW	polysaccharide deacetylase
XDD1_2574	ENOG4105CND	Glycosyl transferase, family 2
XDD1_2576	ENOG4108WS1	
XDD1_2577	ENOG4108KHX	Diguanylate cyclase
XDD1_2578	ENOG41090EK	ompa motb domain protein
XDD1_2579	ENOG4105BZU	Histidine kinase
XDD1_2582	ENOG4105C94	Transporter
XDD1_2583	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
XDD1_2584	ENOG4105C8S	subunit m
XDD1_2585	ENOG4105D65	subunit l
XDD1_2586	ENOG41080EA	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
XDD1_2587	ENOG4107UFS	subunit j
XDD1_2588	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
XDD1_2590	ENOG4108IEH	NADH dehydrogenase subunit g
XDD1_2591	ENOG4107QIZ	NADH dehydrogenase
XDD1_2592	ENOG4105GKE	subunit e
XDD1_2593	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
XDD1_2594	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
XDD1_2595	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
XDD1_2596	ENOG4107NQ8	LysR family Transcriptional regulator
XDD1_2597	ENOG4105CHM	Aminotransferase
XDD1_2598	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
XDD1_2599	ENOG4105DK2	UPF0207 protein
XDD1_2600	ENOG4107QWE	)-transporter
XDD1_2601	ENOG4105EVE	HAD-superfamily hydrolase subfamily IA variant 3
XDD1_2603	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
XDD1_2604	ENOG4105C6K	Malic enzyme
XDD1_2617	ENOG4105DFP	Integrase
XDD1_2618	ENOG410903C	(LipO)protein
XDD1_2619	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
XDD1_2620	ENOG4105KZW	UPF0381 protein
XDD1_2621	ENOG4105CHU	acetyl-coa acetyltransferase
XDD1_2622	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
XDD1_2623	ENOG4108BY2	phosphohistidine phosphatase
XDD1_2624	ENOG4108DG9	Smr protein MutS2
XDD1_2625	ENOG4105CI2	imidazolone-5-propionate hydrolase
XDD1_2626	ENOG41088SP	formiminoglutamate hydrolase
XDD1_2628	ENOG4105CGP	Urocanate hydratase
XDD1_2629	ENOG4105C84	Histidine ammonia-lyase
XDD1_2630	ENOG4105C85	amino acid
XDD1_2631	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
XDD1_2633	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
XDD1_2634	ENOG4105EJ9	Membrane
XDD1_2635	ENOG4108BPE	-transporting atpase
XDD1_2636	ENOG4105MH2	YfcL protein
XDD1_2638	ENOG4105XYF	acetyltransferase
XDD1_2639	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
XDD1_2640	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
XDD1_2646	ENOG4105DHQ	Histidine kinase
XDD1_2649	ENOG4105CJ0	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity)
XDD1_2650	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
XDD1_2651	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
XDD1_2652	ENOG4105DQR	SNARE associated Golgi
XDD1_2653	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
XDD1_2654	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
XDD1_2655	ENOG4108S3P	Sporulation domain protein
XDD1_2656	ENOG4105E96	Colicin v production protein
XDD1_2657	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
XDD1_2658	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
XDD1_2659	ENOG4105ECP	epimerase
XDD1_2660	ENOG4105CYM	Glutathione S-transferase
XDD1_2661	ENOG4105PTV	Nudix Hydrolase
XDD1_2669	ENOG4105IBP	Cyclic peptide transporter
XDD1_2670	ENOG4105C8Y	Acetylornithine aminotransferase
XDD1_2671	ENOG4105F4X	arginine
XDD1_2672	ENOG4105C26	Dehydrogenase
XDD1_2673	ENOG4105EY2	Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2) (By similarity)
XDD1_2674	ENOG4107UI5	Transforms N(2)-succinylglutamate into succinate and glutamate (By similarity)
XDD1_2675	ENOG4105C85	amino acid
XDD1_2682	ENOG4105CEY	Amp-dependent synthetase and ligase
XDD1_2683	ENOG4105CHR	reductase
XDD1_2693	ENOG4105XA0	heptosyltransferase ii
XDD1_2694	ENOG4105CT5	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate (By similarity)
XDD1_2696	ENOG4107W7X	Aldolase
XDD1_2698	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
XDD1_2699	ENOG4105CHR	reductase
XDD1_2700	ENOG4105D9N	nucleoside
XDD1_2701	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
XDD1_2702	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
XDD1_2703	ENOG4105EXN	Sulfate transport protein CysZ
XDD1_2704	ENOG4105C6T	cysteine synthase
XDD1_2705	ENOG4105KZ7	phosphocarrier protein hpr
XDD1_2707	ENOG4105C5Y	PTS System
XDD1_2708	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
XDD1_2720	ENOG4105C1G	acyl-Coa dehydrogenase
XDD1_2721	ENOG4105X96	Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Activated D-alanyl-Dcp donates its D-alanyl substituent to membrane-associated LTA (By similarity)
XDD1_2723	ENOG4105C6T	cysteine synthase
XDD1_2726	ENOG4105F38	ABC transporter, permease
XDD1_2727	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
XDD1_2728	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
XDD1_2733	ENOG4108IJ6	ABC transporter
XDD1_2734	ENOG4105ECW	sulfate abc transporter
XDD1_2735	ENOG4108I5D	sulfate abc transporter
XDD1_2736	ENOG4105E7K	(LipO)protein
XDD1_2739	ENOG4108R6G	acetyltransferase
XDD1_2756	ENOG4105CAR	Terminase, large subunit
XDD1_2758	ENOG4105HVQ	Regulatory factor of maltose metabolism
XDD1_2759	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
XDD1_2766	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
XDD1_2767	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
XDD1_2768	ENOG4105N21	Membrane
XDD1_2769	ENOG4105CUT	histidyl-tRNA synthetase
XDD1_2770	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
XDD1_2773	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
XDD1_2774	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
XDD1_2775	ENOG4105VMP	Transcriptional regulator
XDD1_2777	ENOG4108JQB	penicillin-binding protein 1C
XDD1_2778	ENOG4105DN3	alpha-2-macroglobulin domain protein
XDD1_2780	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
XDD1_2781	ENOG4105WVQ	Fe-S assembly protein IscX
XDD1_2782	ENOG4108ZIT	Ferredoxin, 2FE-2S
XDD1_2783	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
XDD1_2784	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
XDD1_2785	ENOG4108Z4V	iron-sulfur cluster assembly
XDD1_2786	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
XDD1_2787	ENOG4105C3J	Cysteine desulfurase
XDD1_2788	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
XDD1_2789	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
XDD1_2790	ENOG4105ECY	inositol monophosphatase
XDD1_2791	ENOG4105D8G	Major Facilitator superfamily
XDD1_2792	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
XDD1_2793	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
XDD1_2794	ENOG4108YZA	Nitrogen regulatory protein pii
XDD1_2795	ENOG4105C4K	Nad synthetase
XDD1_2796	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
XDD1_2797	ENOG4108SKK	alpha helix protein
XDD1_2798	ENOG4107WP9	Histidine kinase
XDD1_2799	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
XDD1_2800	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
XDD1_2801	ENOG4108Z6B	deaminase
XDD1_2802	ENOG4105EST	Metal Dependent Phosphohydrolase
XDD1_2803	ENOG4105D03	DNA-3-methyladenine glycosylase II
XDD1_2805	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
XDD1_2806	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
XDD1_2807	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
XDD1_2808	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
XDD1_2809	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
XDD1_2810	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
XDD1_2811	ENOG4105C3F	Signal peptidase i
XDD1_2812	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
XDD1_2813	ENOG4105WMJ	Positive regulator of sigma E, RseC MucC
XDD1_2816	ENOG4105EMN	RNA polymerase sigma factor
XDD1_2817	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
XDD1_2818	ENOG4105C1J	atp-dependent rna helicase
XDD1_2820	ENOG4108VKA	Acts as a radical domain for damaged PFL and possibly other radical proteins (By similarity)
XDD1_2821	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
XDD1_2822	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
XDD1_2823	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
XDD1_2824	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
XDD1_2825	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
XDD1_2826	ENOG4105VDB	UPF0125 protein
XDD1_2827	ENOG4108Z1B	Cyclase dehydrase
XDD1_2828	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
XDD1_2835	ENOG4105PTU	response to oxidative stress
XDD1_2858	ENOG4105ED4	portal protein
XDD1_2862	ENOG4105VZ1	Replication Protein
XDD1_2870	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
XDD1_2881	ENOG4108JU7	Transcriptional regulator
XDD1_2882	ENOG4105CR4	methylisocitrate lyase
XDD1_2883	ENOG4105BZN	citrate synthase
XDD1_2884	ENOG4105DXD	2-methylcitrate dehydratase
XDD1_2885	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
XDD1_2889	ENOG4105DS1	cytochrome b561
XDD1_2890	ENOG4108YYC	ycei family
XDD1_2894	ENOG4108IND	Tetr family transcriptional regulator
XDD1_2895	ENOG4105F27	Major Facilitator
XDD1_2897	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
XDD1_2899	ENOG4105Z2P	Protein of unknown function (DUF465)
XDD1_2900	ENOG4105ZTC	transcriptional activator, Ogr delta
XDD1_2910	ENOG4105UZW	Tail fiber assembly protein
XDD1_2911	ENOG4105UZW	Tail fiber assembly protein
XDD1_2920	ENOG4105VZ1	Replication Protein
XDD1_2929	ENOG4108KB1	transcriptional regulator, arac family
XDD1_2931	ENOG4105WPN	DNA integration recombination invertion protein
XDD1_2932	ENOG4105CHR	reductase
XDD1_2933	ENOG4105CEY	Amp-dependent synthetase and ligase
XDD1_2937	ENOG4108Z7R	Chaperone CsaA
XDD1_2938	ENOG4108ZI4	Glyoxalase Bleomycin resistance protein (Dioxygenase
XDD1_2942	ENOG4105DD7	kinase (PfkB family
XDD1_2948	ENOG4105CVR	type I restriction-modification system
XDD1_2949	ENOG4107XZC	Restriction modification system DNA (Specificity
XDD1_2951	ENOG4105CRK	lysyL-tRNA synthetase
XDD1_2952	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
XDD1_2953	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
XDD1_2954	ENOG4105T95	Thiol disulfide interChange protein
XDD1_2955	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
XDD1_2956	ENOG41071R3	Low-potential electron donor to a number of redox enzymes (By similarity)
XDD1_2958	ENOG4105Y75	tpr repeat protein
XDD1_2959	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
XDD1_2961	ENOG4105DKK	Benzoate
XDD1_2967	ENOG4105C2C	drug resistance transporter, Bcr CflA
XDD1_2972	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
XDD1_2973	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
XDD1_2974	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
XDD1_2975	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
XDD1_2976	ENOG4105D0A	hydroxylase
XDD1_2977	ENOG4107RAQ	aminopeptidase
XDD1_2978	ENOG4105E07	UPF0149 protein
XDD1_2980	ENOG4107YUN	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
XDD1_2981	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
XDD1_2982	ENOG4108JQ1	Dehydrogenase
XDD1_2984	ENOG4105E66	phosphoriboisomerase A
XDD1_2985	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
XDD1_2986	ENOG4105MPN	Membrane
XDD1_2988	ENOG4108ZUB	Lysine exporter protein (Lyse ygga)
XDD1_2989	ENOG4105D64	Mechanosensitive ion channel
XDD1_2990	ENOG4108ZIG	UPF0231 protein
XDD1_2991	ENOG4107QIJ	Aconitate hydratase 2
XDD1_2994	ENOG4107QN2	dihydrolipoyl dehydrogenase
XDD1_2995	ENOG4107QSN	dihydrolipoamide acetyltransferase
XDD1_2996	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
XDD1_2997	ENOG41073TP	transcriptional regulator
XDD1_3001	ENOG4106A72	regulatory protein AmpE
XDD1_3002	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
XDD1_3003	ENOG4108ZUW	Major pilin subunit
XDD1_3004	ENOG4107QHF	type ii secretion system protein e
XDD1_3006	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
XDD1_3007	ENOG4105DHA	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity)
XDD1_3008	ENOG4105M6F	mutator MutT protein
XDD1_3009	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
XDD1_3010	ENOG4108SR7	Regulates secA expression by translational coupling of the secM secA operon. Translational pausing at a specific Pro residue 5 residues before the end of the protein may allow disruption of a mRNA repressor helix that normally suppresses secA translation initiation (By similarity)
XDD1_3012	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
XDD1_3013	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
XDD1_3014	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
XDD1_3015	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
XDD1_3016	ENOG4105CPF	Cell wall formation (By similarity)
XDD1_3017	ENOG4105DFU	Cell wall formation (By similarity)
XDD1_3018	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
XDD1_3019	ENOG4105CNI	cell division protein FtsW
XDD1_3020	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
XDD1_3021	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
XDD1_3022	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
XDD1_3023	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
XDD1_3024	ENOG4105CJN	penicillin-binding protein
XDD1_3025	ENOG41063Y6	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
XDD1_3026	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
XDD1_3027	ENOG4108V6E	Cell division protein mraZ
XDD1_3028	ENOG4107B7Y	DNA-binding transcriptional regulator FruR
XDD1_3029	ENOG4108ZP8	Acetolactate synthase small subunit
XDD1_3030	ENOG4105C7K	acetolactate synthase
XDD1_3031	ENOG4108IQE	Amp-dependent synthetase and ligase
XDD1_3032	ENOG41064T2	transcriptional regulator, lysR family
XDD1_3034	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
XDD1_3036	ENOG4105IRT	Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair (By similarity)
XDD1_3038	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
XDD1_3039	ENOG4105C28	cystathionine
XDD1_3051	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
XDD1_3052	ENOG4105UQX	Mate efflux family protein
XDD1_3053	ENOG4107Y60	(LipO)protein
XDD1_3055	ENOG4106B0W	Curli production assembly transport component CsgG
XDD1_3057	ENOG4105C44	Serine transporter
XDD1_3058	ENOG4108W9T	type 1 fimbriae regulatory protein
XDD1_3059	ENOG4105CKI	cobalamin synthesis protein
XDD1_3060	ENOG4105VCD	cytoplasmic protein
XDD1_3061	ENOG4105D22	carbon starvation protein
XDD1_3062	ENOG4108I6E	Sulfatase
XDD1_3065	ENOG4105C4Y	ABC transporter
XDD1_3067	ENOG4105CXY	transporter
XDD1_3068	ENOG4105BZU	Histidine kinase
XDD1_3069	ENOG4108KX4	response regulator
XDD1_3070	ENOG4105GTG	Isochorismatase
XDD1_3071	ENOG4105FDS	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
XDD1_3072	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
XDD1_3080	ENOG4108WC9	type VI secretion system effector, hcp1 family
XDD1_3090	ENOG4105CAR	Terminase, large subunit
XDD1_3094	ENOG4105HVQ	Regulatory factor of maltose metabolism
XDD1_3097	ENOG4108ZRK	uncharacterized protein yacC
XDD1_3098	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
XDD1_3099	ENOG41077A9	carbonic anhydrase
XDD1_3100	ENOG4105DA5	(ABC) transporter
XDD1_3101	ENOG4105E3A	(ABC) transporter
XDD1_3102	ENOG4107R03	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
XDD1_3103	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
XDD1_3104	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
XDD1_3105	ENOG4105DJ0	Poly(A) Polymerase
XDD1_3106	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
XDD1_3107	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
XDD1_3108	ENOG4105PW4	Sugar fermentation stimulation protein homolog
XDD1_3109	ENOG4105CQ7	ATP-dependent helicase
XDD1_3110	ENOG4105BZ4	penicillin-binding protein
XDD1_3118	ENOG4105E9Z	Nad-dependent epimerase dehydratase
XDD1_3119	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
XDD1_3120	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
XDD1_3121	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
XDD1_3122	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
XDD1_3123	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
XDD1_3124	ENOG4105BZU	Histidine kinase
XDD1_3125	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
XDD1_3126	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
XDD1_3127	ENOG4105DXN	mazG family
XDD1_3128	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
XDD1_3129	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
XDD1_3132	ENOG4105C8P	)-transporter
XDD1_3133	ENOG4105C26	Dehydrogenase
XDD1_3134	ENOG4105CK2	sodium dicarboxylate symporter
XDD1_3137	ENOG4105GPY	SprT protein
XDD1_3138	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
XDD1_3139	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
XDD1_3140	ENOG4105CYW	agmatinase
XDD1_3143	ENOG4108TSE	Transferase
XDD1_3145	ENOG4105CMR	udp-glucose 4-epimerase
XDD1_3146	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
XDD1_3152	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
XDD1_3153	ENOG4107R3N	Filamentation induced by cAMP protein fic
XDD1_3156	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
XDD1_3157	ENOG4105FR9	TRNA-(Ms 2 io 6 A)-hydroxylase
XDD1_3159	ENOG4108K5P	(LipO)protein
XDD1_3160	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
XDD1_3161	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
XDD1_3162	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
XDD1_3163	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
XDD1_3164	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
XDD1_3165	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
XDD1_3167	ENOG4107UCJ	Catalyzes the synthesis of activated sulfate (By similarity)
XDD1_3168	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
XDD1_3169	ENOG4105C11	sulfate adenylyltransferase), subunit 2
XDD1_3170	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
XDD1_3171	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
XDD1_3172	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
XDD1_3173	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
XDD1_3175	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
XDD1_3176	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
XDD1_3177	ENOG4105C85	amino acid
XDD1_3178	ENOG4107NA1	Endonuclease Exonuclease phosphatase
XDD1_3184	ENOG4108RR8	protoporphyrinogen oxidase
XDD1_3185	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
XDD1_3186	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
XDD1_3187	ENOG4105D9Y	Splits dipeptides with a prolyl residue in the C- terminal position (By similarity)
XDD1_3188	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
XDD1_3189	ENOG4105CHU	acetyl-coa acetyltransferase
XDD1_3191	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
XDD1_3192	ENOG4105MDZ	Transcriptional activator rfaH
XDD1_3193	ENOG4105D52	delta-aminolevulinic acid dehydratase
XDD1_3194	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
XDD1_3195	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
XDD1_3196	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
XDD1_3197	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
XDD1_3198	ENOG4105JC1	sterol-binding domain protein
XDD1_3199	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
XDD1_3200	ENOG4105CGY	Dna recombination protein
XDD1_3201	ENOG4108KF1	Membrane
XDD1_3203	ENOG4108I5U	Uridine phosphorylase
XDD1_3204	ENOG4105C6Z	Gluconate
XDD1_3205	ENOG4105C6Z	Gluconate
XDD1_3206	ENOG4105EXW	epimerase dehydratase
XDD1_3207	ENOG4105MVE	transcriptional regulator
XDD1_3208	ENOG4105QG4	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
XDD1_3209	ENOG4105G63	Type III effector Hrp-dependent
XDD1_3210	ENOG4105ZXK	Dehydrogenase
XDD1_3214	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
XDD1_3215	ENOG4105DZ2	Transcriptional regulator
XDD1_3216	ENOG4105EMK	carboxylate amino acid amine transporter
XDD1_3217	ENOG4105EEQ	Na H antiporter
XDD1_3218	ENOG4105C7N	Xanthine uracil vitamin C permease
XDD1_3222	ENOG41072TH	Protein of unknown function (DUF1479)
XDD1_3223	ENOG4105CHC	glucokinase (EC 2.7.1.2)
XDD1_3226	ENOG4108UUM	single-stranded DNA-binding protein
XDD1_3227	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
XDD1_3230	ENOG4105CGF	Aromatic amino acid aminotransferase
XDD1_3231	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
XDD1_3232	ENOG4105CDU	Replicative dna helicase
XDD1_3233	ENOG4105HVQ	Regulatory factor of maltose metabolism
XDD1_3245	ENOG4108WC9	type VI secretion system effector, hcp1 family
XDD1_3253	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
XDD1_3254	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
XDD1_3256	ENOG4105MYN	Zinc uptake regulation protein
XDD1_3257	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
XDD1_3258	ENOG41080IJ	Diacylglycerol kinase
XDD1_3259	ENOG4105E55	glycerol-3-phosphate acyltransferase
XDD1_3260	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
XDD1_3261	ENOG4105VEI	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
XDD1_3262	ENOG4107QP8	phosphohexose isomerase
XDD1_3263	ENOG4105CFH	Aspartokinase
XDD1_3265	ENOG4105W2W	Cytotoxic translational repressor of toxin-antitoxin stability system
XDD1_3267	ENOG41069M3	Transcriptional regulator
XDD1_3268	ENOG4108UHU	Aldolase
XDD1_3269	ENOG4105VS7	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity)
XDD1_3270	ENOG4108I9X	Isocitrate lyase
XDD1_3271	ENOG4107QP3	malate synthase g
XDD1_3272	ENOG4105CVG	Homoserine O-transsuccinylase
XDD1_3277	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
XDD1_3278	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
XDD1_3279	ENOG4108UMI	ABC transporter, permease
XDD1_3280	ENOG4105D01	(LipO)protein
XDD1_3283	ENOG4108R96	Methyltransferase, YaeB family
XDD1_3284	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
XDD1_3285	ENOG4107EII	Lipoprotein involved with copper homeostasis and adhesion
XDD1_3286	ENOG4105M1T	rho-binding antiterminator
XDD1_3288	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
XDD1_3290	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
XDD1_3291	ENOG4105C0B	DNA polymerase III (alpha subunit)
XDD1_3292	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
XDD1_3293	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
XDD1_3294	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
XDD1_3295	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
XDD1_3296	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
XDD1_3297	ENOG4108RFI	Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity)
XDD1_3298	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XDD1_3299	ENOG4105DZP	Membrane-associated zinc metalloprotease
XDD1_3300	ENOG4105KNE	Phosphatidate cytidylyltransferase
XDD1_3301	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
XDD1_3302	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
XDD1_3303	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
XDD1_3304	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
XDD1_3305	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
XDD1_3306	ENOG4105CE9	30S ribosomal protein S2
XDD1_3307	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
XDD1_3308	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
XDD1_3311	ENOG4108T8E	UPF0325 protein
XDD1_3312	ENOG4105QDK	Flavodoxin
XDD1_3314	ENOG4105DR9	pseudouridine synthase
XDD1_3315	ENOG4105WP7	tRNA pseudouridine synthase C
XDD1_3316	ENOG4108T6E	Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function (By similarity)
XDD1_3320	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
XDD1_3323	ENOG4105CIQ	May have a role in processing of nucleic acids. It is probably not an exonuclease
XDD1_3324	ENOG4105DFG	type I secretion outer membrane protein
XDD1_3325	ENOG4107QZV	Type I secretion membrane fusion protein
XDD1_3326	ENOG4108JJ6	Type I secretion system ATPase
XDD1_3327	ENOG41065N1	inhibitor
XDD1_3333	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
XDD1_3334	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
XDD1_3341	ENOG4105C57	major facilitator superfamily
XDD1_3344	ENOG4105CHR	reductase
XDD1_3345	ENOG4105CHR	reductase
XDD1_3347	ENOG4105M08	Membrane
XDD1_3348	ENOG4105ETT	transcriptional Regulator, LysR family
XDD1_3350	ENOG4105C9B	Cysteine desulfurase
XDD1_3354	ENOG4108WC9	type VI secretion system effector, hcp1 family
XDD1_3355	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
XDD1_3356	ENOG4105CUZ	uba thif-type nad fad binding protein
XDD1_3357	ENOG4105CA3	membrane-bound lytic murein transglycosylase
XDD1_3358	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
XDD1_3359	ENOG4107QZM	n-acetylglutamate synthase
XDD1_3360	ENOG4107QYX	exodeoxyribonuclease v alpha
XDD1_3361	ENOG4107QKA	exodeoxyribonuclease V beta
XDD1_3362	ENOG4107QXK	peptidase
XDD1_3363	ENOG4105DSY	exodeoxyribonuclease V, gamma
XDD1_3366	ENOG4105JCS	prepilin peptidase dependent protein
XDD1_3367	ENOG4105IPU	prepilin peptidase dependent protein A
XDD1_3371	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
XDD1_3372	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
XDD1_3373	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
XDD1_3374	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
XDD1_3375	ENOG4105DP9	ABC transporter
XDD1_3376	ENOG4106SMU	thiamine transporter membrane protein
XDD1_3377	ENOG4107T0D	ABC, transporter
XDD1_3381	ENOG4105CQ2	DNA polymerase
XDD1_3382	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
XDD1_3383	ENOG4105D3G	Pseudouridine synthase
XDD1_3384	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
XDD1_3386	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
XDD1_3387	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
XDD1_3388	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
XDD1_3389	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
XDD1_3390	ENOG4105NWN	ApaG protein
XDD1_3391	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
XDD1_3392	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
XDD1_3393	ENOG4107TZ2	Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress (By similarity)
XDD1_3394	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
XDD1_3396	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
XDD1_3397	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
XDD1_3398	ENOG4105IPS	esterase
XDD1_3399	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
XDD1_3400	ENOG41087AY	ADP-Ribose pyrophosphatase
XDD1_3401	ENOG4105DFG	type I secretion outer membrane protein
XDD1_3402	ENOG4105F1G	UPF0441 protein
XDD1_3403	ENOG4106032	Glutathionylspermidine synthase
XDD1_3404	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
XDD1_3405	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
XDD1_3406	ENOG4105W0Z	cytoplasmic protein
XDD1_3407	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
XDD1_3408	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
XDD1_3409	ENOG4105I7R	Adenylate cyclase
XDD1_3410	ENOG4106MWK	domain protein
XDD1_3411	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
XDD1_3412	ENOG4107ZVW	dihydroneopterin aldolase
XDD1_3413	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
XDD1_3414	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
XDD1_3415	ENOG4105VCC	30S ribosomal protein S21
XDD1_3416	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
XDD1_3417	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
XDD1_3420	ENOG4105PF0	Antitoxin component of a toxin-antitoxin (TA) module. Functions as an mRNA interferase antitoxin
XDD1_3424	ENOG4105PTU	response to oxidative stress
XDD1_3445	ENOG4105ED4	portal protein
XDD1_3449	ENOG4105VZ1	Replication Protein
XDD1_3457	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
XDD1_3462	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
XDD1_3466	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
XDD1_3474	ENOG4105C2D	reductase
XDD1_3477	ENOG4105K5X	acetyltransferase
XDD1_3479	ENOG4108MJ5	VirK protein
XDD1_3481	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
XDD1_3482	ENOG4107QV7	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
XDD1_3483	ENOG4106W5V	Membrane
XDD1_3484	ENOG4105NE1	Conserved Protein
XDD1_3485	ENOG41090KG	Inner membrane protein YqjE
XDD1_3487	ENOG4108VBZ	doxx family
XDD1_3488	ENOG4105CWB	LysR family transcriptional Regulator
XDD1_3489	ENOG4108CNN	domain protein
XDD1_3490	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
XDD1_3492	ENOG41082RQ	UPF0102 protein
XDD1_3493	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
XDD1_3494	ENOG4105W4M	Transport-associated protein
XDD1_3501	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
XDD1_3502	ENOG4108556	Isoprenoid biosynthesis protein with amidotransferase-like domain
XDD1_3503	ENOG4105BZU	Histidine kinase
XDD1_3504	ENOG4105CBC	glutamate synthase
XDD1_3505	ENOG4105BZ8	glutamate synthase
XDD1_3507	ENOG4105KB2	stringent starvation protein b
XDD1_3508	ENOG4107MKT	Stringent starvation protein a
XDD1_3509	ENOG4108UJD	30S ribosomal protein S9
XDD1_3510	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
XDD1_3511	ENOG4105D6Z	AFG1 family ATPase
XDD1_3512	ENOG4108W2Q	Cytochrome d ubiquinol oxidase subunit III
XDD1_3513	ENOG4105C0H	protease
XDD1_3514	ENOG4105C0H	protease
XDD1_3515	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
XDD1_3516	ENOG4105VFK	BolA family
XDD1_3518	ENOG4105E3I	toluene tolerance
XDD1_3519	ENOG4107PE3	Mammalian cell entry related domain protein
XDD1_3520	ENOG4105CY3	ABC transporter, permease
XDD1_3521	ENOG4105DHJ	ABC, transporter
XDD1_3522	ENOG4105FEU	K -dependent Na -Ca exchanger
XDD1_3523	ENOG4105C2X	Arabinose 5-phosphate isomerase
XDD1_3524	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
XDD1_3525	ENOG4108P1K	Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane (By similarity)
XDD1_3526	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
XDD1_3527	ENOG4108IUZ	ABC transporter
XDD1_3528	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
XDD1_3529	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
XDD1_3530	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
XDD1_3531	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
XDD1_3532	ENOG41080Z8	PHOSPHOCARRIER protein
XDD1_3535	ENOG4105NXH	GreA GreB family elongation factor
XDD1_3538	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
XDD1_3539	ENOG4105N42	UPF0307 protein
XDD1_3540	ENOG4108JQ1	Dehydrogenase
XDD1_3541	ENOG4105RC8	Reduces the permeability of the outer membrane to copper. Seems to be involved in the regulation of biofilm formation. May decrease biofilm formation by repressing cell-cell interaction and cell surface interaction
XDD1_3542	ENOG4108Z4X	TRANSCRIPTIONal
XDD1_3545	ENOG4105BZS	acriflavin resistance protein
XDD1_3546	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
XDD1_3548	ENOG4105QD6	exported protein
XDD1_3549	ENOG4105C03	ribonuclease
XDD1_3550	ENOG4108Z03	MAF-like protein
XDD1_3551	ENOG4105VQ7	Rod shape-determining protein MreD
XDD1_3552	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
XDD1_3553	ENOG4105DFF	Rod shape-determining protein mreb
XDD1_3555	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
XDD1_3556	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
XDD1_3557	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
XDD1_3558	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
XDD1_3559	ENOG4105RG0	Membrane
XDD1_3560	ENOG4108IA2	Sodium pantothenate symporter
XDD1_3561	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
XDD1_3563	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
XDD1_3567	ENOG4108WC9	type VI secretion system effector, hcp1 family
XDD1_3573	ENOG4108WRK	Transcriptional regulator
XDD1_3574	ENOG4105BZW	Glycerate kinase
XDD1_3576	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
XDD1_3577	ENOG4105CAK	Cell division ATP-binding protein ftsE
XDD1_3578	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
XDD1_3578	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
XDD1_3579	ENOG4106H78	methyltransferase
XDD1_3580	ENOG4105MG3	Membrane
XDD1_3582	ENOG4105C59	p-type ATPase
XDD1_3583	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
XDD1_3584	ENOG4105EX9	Membrane
XDD1_3586	ENOG4105C0W	non-ribosomal peptide synthetase
XDD1_3587	ENOG4105CXY	transporter
XDD1_3588	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
XDD1_3589	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
XDD1_3592	ENOG4108WJH	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
XDD1_3593	ENOG4108VP9	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
XDD1_3594	ENOG4107ENK	receptor
XDD1_3596	ENOG4108JIK	carboxylase
XDD1_3598	ENOG4105E7W	lamb ycsf family protein
XDD1_3599	ENOG4105C5A	transporter
XDD1_3607	ENOG4105DC1	bifunctional purine biosynthesis protein purh
XDD1_3608	ENOG4105C12	Phosphoribosylglycinamide synthetase
XDD1_3609	ENOG4108T8B	Protein of unknown function (DUF1481)
XDD1_3610	ENOG4105K70	DNA-binding protein
XDD1_3611	ENOG4105R2J	Conserved Protein
XDD1_3612	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
XDD1_3614	ENOG4105E09	nadh pyrophosphatase
XDD1_3615	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
XDD1_3616	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
XDD1_3617	ENOG4105D06	uba thif-type nad fad binding protein
XDD1_3619	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
XDD1_3620	ENOG4105D41	biosynthesis protein thiH
XDD1_3621	ENOG4108RJ7	Catalyzes the hydrolysis of nucleoside triphosphates, with a preference for pyrimidine deoxynucleoside triphosphates (dUTP, dTTP and dCTP) (By similarity)
XDD1_3622	ENOG4107UW8	HAD-superfamily hydrolase subfamily IA variant 3
XDD1_3625	ENOG4106UW1	Major Facilitator superfamily
XDD1_3626	ENOG4107YBY	Hydrolase
XDD1_3628	ENOG4108JPW	Aminotransferase
XDD1_3629	ENOG41061ZR	Transcriptional regulator
XDD1_3631	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
XDD1_3632	ENOG4107RTM	4-alpha-glucanotransferase (EC 2.4.1.25)
XDD1_3633	ENOG4105EG2	ABC transporter, permease
XDD1_3634	ENOG4105D56	permease protein
XDD1_3635	ENOG4107FKK	extracellular solute-binding protein family 1
XDD1_3636	ENOG4108IJ9	(ABC) transporter
XDD1_3637	ENOG4108KDD	Involved in the transport of maltose and maltodextrins (By similarity)
XDD1_3638	ENOG4107W52	maltose operon periplasmic protein
XDD1_3639	ENOG4107BJW	polysaccharide deacetylase
XDD1_3640	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
XDD1_3641	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
XDD1_3642	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
XDD1_3643	ENOG4108VZM	50s ribosomal protein L10
XDD1_3644	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
XDD1_3645	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
XDD1_3646	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
XDD1_3647	ENOG4105PM1	preprotein translocase subunit SecE
XDD1_3648	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
XDD1_3649	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
XDD1_3650	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
XDD1_3651	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
XDD1_3652	ENOG4105YKK	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
XDD1_3653	ENOG4108ZKU	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
XDD1_3654	ENOG4108ZAT	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity)
XDD1_3655	ENOG4105WWK	YheO domain protein
XDD1_3656	ENOG4108V1T	peptidylprolyl cis-trans isomerase
XDD1_3657	ENOG4105VRX	Protein slyX homolog
XDD1_3658	ENOG4108YZY	peptidylprolyl cis-trans isomerase
XDD1_3659	ENOG4105VKU	nucleicacid-binding protein
XDD1_3660	ENOG4105C5H	ABC transporter
XDD1_3661	ENOG4105DDW	LysR family Transcriptional regulator
XDD1_3662	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
XDD1_3663	ENOG4108EKE	The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in N-acetylmuramic acid (MurNAc) transport, yielding cytoplasmic MurNAc-6-P. Is also able to take up anhydro-N-acetylmuramic acid (anhMurNAc), but cannot phosphorylate the carbon 6, probably because of the 1,6-anhydro ring (By similarity)
XDD1_3665	ENOG4105YP7	UPF0270 protein
XDD1_3666	ENOG4105CJE	phosphoribulokinase (EC 2.7.1.19)
XDD1_3667	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
XDD1_3668	ENOG4105C8Y	Acetylornithine aminotransferase
XDD1_3670	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
XDD1_3671	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
XDD1_3672	ENOG4105C2M	dna polymerase I
XDD1_3673	ENOG4108Z33	Thiol disulfide Interchange Protein
XDD1_3674	ENOG4105E27	serine threonine protein kinase
XDD1_3675	ENOG4105PC1	Conserved Protein
XDD1_3681	ENOG4105D6S	protein involved in catabolism of external DNA
XDD1_3682	ENOG4105DC8	reductase
XDD1_3684	ENOG4108EMV	Catalyzes the phosphorylation of autoinducer 2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon. Phosphorylates the ring-open form of 4,5-dihydroxy-2,3- pentanedione (DPD), which is the precursor to all AI-2 signaling molecules, at the C5 position (By similarity)
XDD1_3685	ENOG4105DKT	Transcriptional regulator
XDD1_3688	ENOG4105F5R	ABC transporter
XDD1_3690	ENOG41061GT	Aldolase
XDD1_3691	ENOG4105K34	Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the cleavage of phosphorylated 4,5- dihydroxy-2,3-pentanedione (P-DPD) to 2-phosphoglycolic acid (PG) and another three-carbon compound
XDD1_3692	ENOG4105DY8	decarboxylase
XDD1_3693	ENOG4105FNP	Molybdopterin-guanine dinucleotide biosynthesis protein b
XDD1_3694	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
XDD1_3701	ENOG4105CNA	YD repeat protein
XDD1_3710	ENOG4105CNA	YD repeat protein
XDD1_3713	ENOG4105CS6	Rhs element vgr protein
XDD1_3720	ENOG4105CNA	YD repeat protein
XDD1_3733	ENOG4105CNA	YD repeat protein
XDD1_3736	ENOG4105CS6	Rhs element vgr protein
XDD1_3745	ENOG4105CNA	YD repeat protein
XDD1_3747	ENOG4105CS6	Rhs element vgr protein
XDD1_3756	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
XDD1_3766	ENOG4108WC9	type VI secretion system effector, hcp1 family
XDD1_3768	ENOG4106IWJ	hemolysin
XDD1_3769	ENOG4107H3J	ribonuclease
XDD1_3770	ENOG4105VSH	4-oxalocrotonate tautomerase
XDD1_3773	ENOG4105HSS	phospholipase C
XDD1_3774	ENOG4105CS0	peptidase
XDD1_3775	ENOG4105BZU	Histidine kinase
XDD1_3776	ENOG4108JQ7	(ABC) transporter
XDD1_3777	ENOG4105C3U	ABC transporter
XDD1_3778	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
XDD1_3779	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
XDD1_3780	ENOG4105DEF	Extracellular solute-binding protein, family 5
XDD1_3790	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
XDD1_3791	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
XDD1_3792	ENOG4108R3E	Dna-3-methyladenine glycosylase i
XDD1_3797	ENOG4105JKW	Valine--pyruvate aminotransferase
XDD1_3798	ENOG4105R2A	(LipO)protein
XDD1_3799	ENOG4105D99	atp gtp-binding protein
XDD1_3800	ENOG4105EN6	Membrane
XDD1_3802	ENOG410649J	Catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction (By similarity)
XDD1_3803	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
XDD1_3804	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
XDD1_3805	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
XDD1_3806	ENOG4105CB5	ATP-dependent DNA helicase recG
XDD1_3808	ENOG4105D6U	Sodium Glutamate Symporter
XDD1_3809	ENOG4105C2W	permease
XDD1_3811	ENOG4105SUU	thioesterase domain
XDD1_3812	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
XDD1_3816	ENOG4105EJU	HAD-superfamily hydrolase subfamily IA variant 3
XDD1_3823	ENOG4105F9F	transposase
XDD1_3824	ENOG4105TNG	K13735 adhesin invasin
XDD1_3835	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
XDD1_3836	ENOG4105MZG	transcriptional modulator of maze toxin, mazf
XDD1_3840	ENOG4105D4P	Coproporphyrinogen iii oxidase
XDD1_3843	ENOG4105C7N	Xanthine uracil vitamin C permease
XDD1_3848	ENOG4105GMB	type VI secretion system effector, hcp1 family
XDD1_3849	ENOG4105DRP	amino acid AbC transporter
XDD1_3850	ENOG4105EAD	ABC transporter
XDD1_3851	ENOG4105CT1	(ABC) transporter
XDD1_3852	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
XDD1_3853	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
XDD1_3854	ENOG4105E2Z	phosphate ABC transporter (Permease
XDD1_3855	ENOG4105C8U	phosphate abc transporter
XDD1_3856	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
XDD1_3862	ENOG4105E0F	Histidine kinase
XDD1_3863	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
XDD1_3864	ENOG4108RRZ	Transcription elongation factor GreB
XDD1_3865	ENOG4105BZM	domain protein
XDD1_3866	ENOG4105XFK	Ferrous iron transport protein A
XDD1_3868	ENOG41060N5	May function as a transcriptional regulator that controls feoABC expression (By similarity)
XDD1_3870	ENOG410642W	LysR family Transcriptional regulator
XDD1_3877	ENOG4108I2E	Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
XDD1_3886	ENOG4105XT2	Transcriptional regulator
XDD1_3890	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
XDD1_3891	ENOG4105MJ2	Competence protein
XDD1_3892	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
XDD1_3893	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
XDD1_3894	ENOG4105EBW	Rhomboid-type serine protease that catalyzes intramembrane proteolysis (By similarity)
XDD1_3895	ENOG4105E98	transcriptional regulator DeoR family
XDD1_3896	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
XDD1_3904	ENOG4108M21	
XDD1_3905	ENOG4105RMW	regulation of transcription, DNA-dependent
XDD1_3906	ENOG4108626	Racemase
XDD1_3908	ENOG41080QX	K07048 phosphotriesterase-related protein
XDD1_3909	ENOG4105MUZ	Protein of unknown function DUF2620
XDD1_3910	ENOG4106M0N	transport system permease protein
XDD1_3911	ENOG4106PKC	pyridoxal phosphate binding
XDD1_3914	ENOG4108WC9	type VI secretion system effector, hcp1 family
XDD1_3917	ENOG4105DXM	phenylacetic acid degradation protein
XDD1_3918	ENOG4105CRS	phenylacetate-CoA oxygenase PaaG subunit
XDD1_3919	ENOG4105N76	Phenylacetate-CoA oxygenase, subunit
XDD1_3920	ENOG4105D9S	phenylacetate-CoA oxygenase PaaI subunit
XDD1_3921	ENOG4108ZA2	phenylacetate-CoA oxygenase PaaJ subunit
XDD1_3922	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
XDD1_3923	ENOG4105E39	Enoyl-CoA hydratase
XDD1_3924	ENOG4108UKI	Enoyl-CoA hydratase
XDD1_3925	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
XDD1_3926	ENOG4108ZJI	phenylacetic acid degradation protein
XDD1_3927	ENOG4105CHU	acetyl-coa acetyltransferase
XDD1_3928	ENOG4105DZS	Phenylacetate-CoA ligase
XDD1_3929	ENOG4105F27	Major Facilitator
XDD1_3939	ENOG4105D7K	pfkb domain protein
XDD1_3941	ENOG4105FDP	GntR family transcriptional regulator
XDD1_3942	ENOG4107T7U	Sulfatase
XDD1_3945	ENOG4105EM7	Selenocysteine-specific translation elongation factor
XDD1_3950	ENOG4108WC9	type VI secretion system effector, hcp1 family
XDD1_3954	ENOG4105C1Y	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis (By similarity)
XDD1_3955	ENOG4105F46	Necessary for formate dehydrogenase activity (By similarity)
XDD1_3958	ENOG4108MG3	formate dehydrogenase
XDD1_3960	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
XDD1_3961	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
XDD1_3962	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
XDD1_3963	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
XDD1_3970	ENOG41067XB	TonB family
XDD1_3971	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
XDD1_3972	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
XDD1_3973	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
XDD1_3974	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
XDD1_p0001	ENOG4105HVQ	Regulatory factor of maltose metabolism