locus-tag	class	description
XFFB_00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
XFFB_00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
XFFB_00015	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
XFFB_00025	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
XFFB_00035	ENOG4108K0D	peptidase, M48
XFFB_00075	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
XFFB_00095	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
XFFB_00110	ENOG4108ZUW	Major pilin subunit
XFFB_00140	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
XFFB_00145	ENOG4105CGF	Aromatic amino acid aminotransferase
XFFB_00185	ENOG4108JA2	transcriptioN-repair coupling factor
XFFB_00195	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
XFFB_00200	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
XFFB_00205	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
XFFB_00210	ENOG4105C4R	Atp-dependent dna helicase
XFFB_00220	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
XFFB_00235	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
XFFB_00245	ENOG4105MJ2	Competence protein
XFFB_00250	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
XFFB_00255	ENOG4105D78	K07001 NTE family protein
XFFB_00295	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
XFFB_00305	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
XFFB_00340	ENOG4108VEV	chaperone
XFFB_00345	ENOG4105X0I	Fimbrial
XFFB_00350	ENOG4107TH8	cina domain protein
XFFB_00355	ENOG4105CSH	Transporter
XFFB_00360	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
XFFB_00365	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
XFFB_00370	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
XFFB_00375	ENOG4105EEI	dihydropteroate synthase
XFFB_00390	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
XFFB_00395	ENOG4105HBR	Rna-binding protein
XFFB_00405	ENOG4105C01	Dihydroxy-acid dehydratase
XFFB_00430	ENOG4105D1S	lipid A biosynthesis
XFFB_00435	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
XFFB_00445	ENOG4105K5M	30s ribosomal protein S16
XFFB_00450	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
XFFB_00455	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
XFFB_00460	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
XFFB_00465	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
XFFB_00470	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
XFFB_00475	ENOG4105KUZ	arsenate reductase
XFFB_00480	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
XFFB_00485	ENOG4105CAQ	asparagine synthetase
XFFB_00495	ENOG4105EA8	2-Nitropropane dioxygenase
XFFB_00500	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
XFFB_00505	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
XFFB_00525	ENOG4105DGW	oligopeptidase A
XFFB_00540	ENOG4105E3B	Multicopper oxidase
XFFB_00570	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
XFFB_00590	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
XFFB_00600	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
XFFB_00605	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
XFFB_00620	ENOG4105C75	arginyL-tRNA synthetase
XFFB_00625	ENOG4105W5Q	DNA repair protein (RadC
XFFB_00630	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
XFFB_00640	ENOG4107QKV	phosphomannomutase
XFFB_00650	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
XFFB_00690	ENOG4105EYM	Major Facilitator superfamily
XFFB_00700	ENOG4105DR5	peptidase
XFFB_00705	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
XFFB_00735	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
XFFB_00750	ENOG4105C2D	reductase
XFFB_00755	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
XFFB_00760	ENOG4108UT2	hemolysin iii
XFFB_00770	ENOG4105EYA	deoxyribonuclease
XFFB_00785	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
XFFB_00790	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
XFFB_00800	ENOG4107QX8	SPFH domain, Band 7 family protein
XFFB_00805	ENOG4105DXN	mazG family
XFFB_00810	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
XFFB_00815	ENOG4107RK2	ADP-ribose diphosphatase NudE
XFFB_00825	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
XFFB_00830	ENOG4105C1J	atp-dependent rna helicase
XFFB_00835	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
XFFB_00865	ENOG4108YXA	Membrane
XFFB_00870	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
XFFB_00875	ENOG4105C0B	DNA polymerase III (alpha subunit)
XFFB_00880	ENOG4105C8V	SAICAR synthetase
XFFB_00895	ENOG4105CRQ	synthase (Component I)
XFFB_00900	ENOG4105DDQ	anthranilate synthase
XFFB_00905	ENOG4107QYG	anthranilate phosphoribosyltransferase
XFFB_00910	ENOG4105DK0	Indole-3-glycerol phosphate synthase
XFFB_00930	ENOG4105DC7	peptidase M24
XFFB_00945	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
XFFB_00955	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
XFFB_00970	ENOG4105DJ0	Poly(A) Polymerase
XFFB_00975	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
XFFB_00980	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
XFFB_01010	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
XFFB_01015	ENOG4105CHV	Transcription elongation factor NusA
XFFB_01020	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
XFFB_01025	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
XFFB_01035	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
XFFB_01040	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
XFFB_01050	ENOG4105ECR	NmrA family
XFFB_01095	ENOG4105C10	Electron transfer flavoprotein
XFFB_01100	ENOG4105BZJ	Electron transfer flavoprotein
XFFB_01115	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
XFFB_01130	ENOG4107QKV	phosphomannomutase
XFFB_01165	ENOG4105CBP	Major Facilitator
XFFB_01180	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
XFFB_01185	ENOG4105DFU	Cell wall formation (By similarity)
XFFB_01190	ENOG410841Q	phosphoesterase PA-phosphatase related protein
XFFB_01200	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
XFFB_01205	ENOG4105C02	permease
XFFB_012100	ENOG4108C33	Resolvase
XFFB_012125	ENOG4108IYH	Dna topoisomerase
XFFB_012205	ENOG4108UUM	single-stranded DNA-binding protein
XFFB_01225	ENOG4105C0H	protease
XFFB_012290	ENOG4108YIQ	Alpha beta hydrolase
XFFB_01230	ENOG4105ECP	epimerase
XFFB_01240	ENOG4107QM5	aconitate hydratase
XFFB_01250	ENOG4107QIJ	Aconitate hydratase 2
XFFB_01270	ENOG4105DZR	Type I site-specific deoxyribonuclease
XFFB_01325	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
XFFB_01335	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
XFFB_01345	ENOG4105GKE	subunit e
XFFB_01355	ENOG4108IEH	NADH dehydrogenase subunit g
XFFB_01365	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
XFFB_01370	ENOG4105DF2	NADH dehydrogenase subunit j
XFFB_01375	ENOG41080FQ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
XFFB_01380	ENOG4105D65	subunit l
XFFB_01385	ENOG4105C8S	subunit m
XFFB_01390	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
XFFB_01395	ENOG4105CHR	reductase
XFFB_01400	ENOG4105D4T	Citrate transporter
XFFB_01430	ENOG4105D7V	transposase
XFFB_01460	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
XFFB_01470	ENOG41080I0	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
XFFB_01480	ENOG4105CDV	Ompa motb domain protein
XFFB_01490	ENOG4105CQB	FAD linked oxidase domain protein
XFFB_01495	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
XFFB_01500	ENOG4105KME	endoribonuclease L-psp
XFFB_01505	ENOG4105CB5	ATP-dependent DNA helicase recG
XFFB_01510	ENOG4106A3M	Cytochrome p-450
XFFB_01535	ENOG4105CDV	Ompa motb domain protein
XFFB_01540	ENOG4108RVA	ribokinase
XFFB_01545	ENOG4105CPC	Aldo Keto reductase
XFFB_01550	ENOG4108JQC	penicillin-binding protein 1A
XFFB_01585	ENOG4105DIJ	Phosphoethanolamine transferase
XFFB_01590	ENOG4106A3M	Cytochrome p-450
XFFB_01595	ENOG4107S5G	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
XFFB_01620	ENOG4105UGU	tonB-dependent Receptor
XFFB_01635	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
XFFB_01640	ENOG4105IFJ	Histidine kinase
XFFB_01645	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
XFFB_01660	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
XFFB_01670	ENOG4108UQY	Iron-storage protein
XFFB_01715	ENOG4105DU1	integral membrane protein, terc
XFFB_01720	ENOG4105DR4	Methyltransferase
XFFB_01725	ENOG4105CUB	amino acid
XFFB_01740	ENOG4107QSV	RmuC domain protein
XFFB_01765	ENOG4107PE3	Mammalian cell entry related domain protein
XFFB_01770	ENOG4105CY3	ABC transporter, permease
XFFB_01775	ENOG4105DHJ	ABC, transporter
XFFB_01805	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
XFFB_01815	ENOG4105KTH	gatB Yqey
XFFB_01820	ENOG4105VCC	30S ribosomal protein S21
XFFB_01825	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
XFFB_01830	ENOG4107ZVW	dihydroneopterin aldolase
XFFB_01835	ENOG4105CUY	Mechanosensitive ion channel
XFFB_01840	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
XFFB_01855	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
XFFB_01865	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
XFFB_01880	ENOG4105M3Z	response regulator
XFFB_01895	ENOG4105EPW	hflc protein
XFFB_01905	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
XFFB_01910	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
XFFB_01915	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
XFFB_01920	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
XFFB_01940	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
XFFB_01945	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
XFFB_01950	ENOG4105D06	uba thif-type nad fad binding protein
XFFB_01955	ENOG41066DG	(EAL) domain protein
XFFB_01965	ENOG4106855	Competence protein
XFFB_02010	ENOG4108UUM	single-stranded DNA-binding protein
XFFB_02030	ENOG4108ZUW	Major pilin subunit
XFFB_02095	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
XFFB_02140	ENOG4105KUS	lysozyme
XFFB_02235	ENOG4105D7V	transposase
XFFB_02275	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
XFFB_02280	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
XFFB_02285	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
XFFB_02290	ENOG4105E1C	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity)
XFFB_02295	ENOG41082RQ	UPF0102 protein
XFFB_02300	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
XFFB_02305	ENOG41090JD	Blue (Type 1) copper domain protein
XFFB_02315	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
XFFB_02345	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
XFFB_02355	ENOG4105DH7	May be involved in recombination (By similarity)
XFFB_02360	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
XFFB_02370	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
XFFB_02385	ENOG4105C9K	Endothelin-converting enzyme 1
XFFB_02405	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
XFFB_02410	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
XFFB_02420	ENOG4105C02	permease
XFFB_02430	ENOG4108S0S	Nucleotidyl transferase
XFFB_02435	ENOG4105EHM	Aminoglycoside phosphotransferase
XFFB_02440	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
XFFB_02445	ENOG4105CJ2	(LipO)protein
XFFB_02465	ENOG4107E2E	PKHD-type hydroxylase
XFFB_02470	ENOG4108IU3	tonb-dependent siderophore receptor
XFFB_02490	ENOG4105C6T	cysteine synthase
XFFB_02505	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
XFFB_02510	ENOG4108DMA	Nad-dependent epimerase dehydratase
XFFB_02515	ENOG4108IAJ	Nad-dependent epimerase dehydratase
XFFB_02550	ENOG4105VF7	tolerance protein
XFFB_02555	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
XFFB_02560	ENOG4105DWF	phosphomethylpyrimidine kinase
XFFB_02565	ENOG4105E2X	shikimate dehydrogenase
XFFB_02655	ENOG4108V1T	peptidylprolyl cis-trans isomerase
XFFB_02665	ENOG4105CSM	endonuclease III
XFFB_02680	ENOG4108YZY	peptidylprolyl cis-trans isomerase
XFFB_02685	ENOG4105K4H	Nlp p60 protein
XFFB_02690	ENOG4105K4H	Nlp p60 protein
XFFB_02710	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
XFFB_02715	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
XFFB_02720	ENOG4105CTB	Polyprenyl synthetase
XFFB_02750	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
XFFB_02755	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
XFFB_02760	ENOG4105CHR	reductase
XFFB_02770	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
XFFB_02780	ENOG4105HHA	aminodeoxychorismate lyase
XFFB_02785	ENOG4107QRG	dna polymerase iii
XFFB_02805	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
XFFB_02810	ENOG4105ECY	inositol monophosphatase
XFFB_02820	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
XFFB_02830	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
XFFB_02835	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
XFFB_02840	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
XFFB_02870	ENOG4105KWW	Biogenesis protein
XFFB_02875	ENOG4107QX9	Thiol disulfide interChange protein
XFFB_02880	ENOG4105DA4	cytochrome c-type biogenesis protein
XFFB_02885	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
XFFB_02890	ENOG41060IM	Heme exporter protein
XFFB_02900	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
XFFB_02920	ENOG4105FE9	pseudouridine synthase
XFFB_02925	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
XFFB_02930	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
XFFB_02950	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
XFFB_02955	ENOG4105DRS	transport system, permease
XFFB_02975	ENOG4105DWY	Agmatine deiminase
XFFB_02985	ENOG4105CAT	Cytidine monophosphate kinase
XFFB_02990	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
XFFB_02995	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
XFFB_03005	ENOG4105CFV	Tetratricopeptide repeat protein
XFFB_03020	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
XFFB_03025	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
XFFB_03030	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
XFFB_03035	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
XFFB_03055	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
XFFB_03060	ENOG4105K46	50S ribosomal protein l27
XFFB_03065	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
XFFB_03070	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
XFFB_03075	ENOG4105CJR	Integral membrane protein (MviN
XFFB_03080	ENOG4105DTN	riboflavin biosynthesis protein ribF
XFFB_03090	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
XFFB_03155	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
XFFB_03160	ENOG4108JJA	ABC, transporter
XFFB_03190	ENOG4105DQ4	alcohol dehydrogenase
XFFB_03205	ENOG4105BZS	acriflavin resistance protein
XFFB_03210	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
XFFB_03230	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
XFFB_03235	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
XFFB_03240	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
XFFB_03255	ENOG4105D3Q	Sugar transferase
XFFB_03270	ENOG4107UFF	group 1 glycosyl transferase
XFFB_03285	ENOG4108NQK	Catalyzes the transfer of a glucuronic acid (GlcA) residue from UDP-glucuronate to mannose-alpha-1,3-glucose-beta- 1,4-glucose-P-P-polyisoprenyl to form the lipid-linked tetrasaccharide GlcA-Man-Glc(2)-PP-Pol, with a glucuronic acid- beta-mannose linkage. Is involved in the biosynthesis of the exopolysaccharide xanthan, since it catalyzes the fourth glycosylation step in the assembly of the pentasaccharide-P-P- polyisoprenyl repeating unit of xanthan. Is unable to use the trisaccharide acceptor freed from the pyrophosphate lipid moiety. Does not show specificity for the lipidic portion of the acceptor. Shows diminished activity when tested with 6-O-acetyl-mannose- alpha-1,3-glucose-beta-1,4-glucose-P-P-polyisoprenyl, a
XFFB_03290	ENOG4108UHC	Glycosyl transferase, wecb taga cpsf family
XFFB_03295	ENOG4105EFQ	Two component transcriptional regulator (Winged helix family
XFFB_03305	ENOG41080ZE	Adenylate cyclase
XFFB_03315	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
XFFB_03320	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
XFFB_03330	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
XFFB_03345	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
XFFB_03350	ENOG41090R7	Ferric uptake
XFFB_03355	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
XFFB_03360	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
XFFB_03365	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
XFFB_03370	ENOG4105CFG	Acts as a chaperone (By similarity)
XFFB_03375	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
XFFB_03385	ENOG4105ETX	regulatoR
XFFB_03390	ENOG41080IJ	Diacylglycerol kinase
XFFB_03395	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
XFFB_03400	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
XFFB_03415	ENOG4108IUW	ABC transporter
XFFB_03420	ENOG4108SDH	ABC, transporter
XFFB_03430	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
XFFB_03440	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
XFFB_03480	ENOG4105KUS	lysozyme
XFFB_03495	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
XFFB_03500	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
XFFB_03520	ENOG4105D52	delta-aminolevulinic acid dehydratase
XFFB_03525	ENOG4109025	Glyoxalase Bleomycin resistance protein (Dioxygenase
XFFB_03540	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
XFFB_03545	ENOG4105D1F	ATP-binding protein
XFFB_03550	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
XFFB_03605	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
XFFB_03615	ENOG4107QJE	Chromosome Partitioning Protein
XFFB_03620	ENOG4105FA0	parb-like partition protein
XFFB_03640	ENOG410680H	amp-dependent synthetase and ligase
XFFB_03650	ENOG4105WPN	DNA integration recombination invertion protein
XFFB_03655	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
XFFB_03660	ENOG4105DSB	aldose 1-epimerase
XFFB_03670	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
XFFB_03675	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
XFFB_03680	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
XFFB_03690	ENOG4105EPD	Oligopeptide transporter, Opt family
XFFB_03695	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
XFFB_03700	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
XFFB_03715	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
XFFB_03730	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
XFFB_03735	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
XFFB_03740	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
XFFB_03745	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
XFFB_03755	ENOG4105C3F	Signal peptidase i
XFFB_03760	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
XFFB_03765	ENOG4105C0H	protease
XFFB_03775	ENOG4105EMN	RNA polymerase sigma factor
XFFB_03815	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
XFFB_03825	ENOG4105DZ1	carboxypeptidase
XFFB_03830	ENOG4108UJU	UPF0301 protein
XFFB_03840	ENOG4105CXT	aspartate transcarbamylase
XFFB_03845	ENOG4105CFH	Aspartokinase
XFFB_03850	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
XFFB_03860	ENOG4105CUT	histidyl-tRNA synthetase
XFFB_03870	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
XFFB_03880	ENOG4105CIH	Imidazole acetol-phosphate transaminase
XFFB_03885	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
XFFB_03895	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
XFFB_03905	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
XFFB_03910	ENOG4106YVY	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) (By similarity)
XFFB_03915	ENOG4108CAF	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity)
XFFB_03920	ENOG4107QY0	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity)
XFFB_03925	ENOG4105CUB	amino acid
XFFB_03930	ENOG4105CUB	amino acid
XFFB_03935	ENOG4108JQ1	Dehydrogenase
XFFB_03940	ENOG4105CQB	FAD linked oxidase domain protein
XFFB_04035	ENOG4106GMR	
XFFB_04075	ENOG4105VG9	Plasmid stabilization system
XFFB_04110	ENOG4105YES	addiction module antidote protein
XFFB_04115	ENOG4105VUH	addiction module killer protein
XFFB_04135	ENOG4105CZV	ABC transporter
XFFB_04140	ENOG4108V06	Glutathione peroxidase
XFFB_04150	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
XFFB_04170	ENOG4105D7K	pfkb domain protein
XFFB_04180	ENOG4107RVU	D-Ala-D-Ala carboxypeptidase 3 (S13) family
XFFB_04195	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
XFFB_04220	ENOG4108HRK	Histidine kinase
XFFB_04225	ENOG4108NEV	two component transcriptional regulator, LytTR family
XFFB_04230	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
XFFB_04245	ENOG4105CZX	twitching motility protein
XFFB_04250	ENOG4105CZX	twitching motility protein
XFFB_04265	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
XFFB_04275	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
XFFB_04295	ENOG4105M4H	endoribonuclease L-psp
XFFB_04310	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
XFFB_04315	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
XFFB_04320	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
XFFB_04325	ENOG4105DFA	alanine racemase domain protein
XFFB_04335	ENOG4105DFP	Integrase
XFFB_04355	ENOG4105CPC	Aldo Keto reductase
XFFB_04360	ENOG4105CPC	Aldo Keto reductase
XFFB_04365	ENOG4105VW8	4-oxalocrotonate tautomerase
XFFB_04385	ENOG4105HEI	LysR family (Transcriptional regulator
XFFB_04390	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
XFFB_04400	ENOG4105DQ4	alcohol dehydrogenase
XFFB_04405	ENOG4105D8V	Glucose sorbosone dehydrogenase
XFFB_04430	ENOG4105D8V	Glucose sorbosone dehydrogenase
XFFB_04440	ENOG4108TY5	Exhibits lactonase activity. Acts in cells with perturbed membrane integrity and is possibly related to the membrane homeostasis
XFFB_04450	ENOG4107GJV	short-chain dehydrogenase reductase
XFFB_04455	ENOG4105ENX	hydrolase
XFFB_04460	ENOG4105DQ4	alcohol dehydrogenase
XFFB_04475	ENOG4107RTG	Major Facilitator superfamily
XFFB_04480	ENOG4105ENX	hydrolase
XFFB_04490	ENOG4105EQ2	LysR family Transcriptional regulator
XFFB_04580	ENOG4105EQ2	LysR family Transcriptional regulator
XFFB_04625	ENOG4105NI8	Cytosine-specific methyltransferase
XFFB_04635	ENOG4107YH6	single-stranded DNA-binding protein
XFFB_04675	ENOG4107QJE	Chromosome Partitioning Protein
XFFB_04720	ENOG4108194	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
XFFB_04725	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
XFFB_04750	ENOG4107YZP	Rhodanese domain protein
XFFB_04770	ENOG4107R5S	dna adenine
XFFB_04790	ENOG4107QMP	dna polymerase iii subunits gamma and tau
XFFB_04795	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
XFFB_04800	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
XFFB_04805	ENOG4105K59	histidine triad (HIT) protein
XFFB_04815	ENOG4105F8C	transglutaminase domain-containing protein
XFFB_04825	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
XFFB_04835	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
XFFB_04840	ENOG4105VGS	50s ribosomal protein l32
XFFB_04845	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
XFFB_04850	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
XFFB_04855	ENOG4105C7B	Threonine dehydratase
XFFB_04870	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
XFFB_04875	ENOG4105CN1	protease
XFFB_04880	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
XFFB_04885	ENOG4108ZHJ	Organic hydroperoxide resistance protein
XFFB_04890	ENOG4105D6Z	AFG1 family ATPase
XFFB_04915	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
XFFB_04925	ENOG4105RKW	reductase (By
XFFB_04940	ENOG4108J6E	Pfam:Phage_integr_N
XFFB_04950	ENOG4108UUM	single-stranded DNA-binding protein
XFFB_05060	ENOG4106FAK	Endodeoxyribonuclease RusA
XFFB_05075	ENOG4105KUS	lysozyme
XFFB_05115	ENOG4108C66	Inherit from COG: DNA primase
XFFB_05150	ENOG4106GMR	
XFFB_05185	ENOG4105VG9	Plasmid stabilization system
XFFB_05220	ENOG4105YES	addiction module antidote protein
XFFB_05225	ENOG4105VUH	addiction module killer protein
XFFB_05260	ENOG4105D4Y	metalloprotease
XFFB_05280	ENOG4108YYC	ycei family
XFFB_05290	ENOG4105C5F	glutamine synthetase
XFFB_05300	ENOG4105BZU	Histidine kinase
XFFB_05305	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
XFFB_05310	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
XFFB_05315	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
XFFB_05320	ENOG4105CUX	Signal transduction histidine kinase
XFFB_05325	ENOG4105D7V	transposase
XFFB_05345	ENOG4107GFK	fumarate
XFFB_05350	ENOG4105C9M	aspartyl-trna synthetase
XFFB_05355	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
XFFB_05495	ENOG4105CVJ	phosphoglycerate mutase
XFFB_05505	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
XFFB_05510	ENOG4105DP0	ferredoxin-NADP reductase
XFFB_05515	ENOG4108V06	Glutathione peroxidase
XFFB_05520	ENOG4105DUX	Transporter
XFFB_05525	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
XFFB_05530	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
XFFB_05535	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
XFFB_05545	ENOG4105KCK	Peptidoglycan-associated lipoprotein
XFFB_05550	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
XFFB_05560	ENOG4105M8F	Biopolymer transport protein exbD tolR
XFFB_05565	ENOG4105E02	MotA TolQ exbB proton channel
XFFB_05570	ENOG4107YD3	Thioesterase
XFFB_05575	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
XFFB_05580	ENOG4105DFH	Transport of potassium into the cell (By similarity)
XFFB_05585	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
XFFB_05590	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
XFFB_05595	ENOG4105CDY	transcriptional regulatory protein
XFFB_05600	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
XFFB_05605	ENOG4105CEN	a g-specific adenine glycosylase
XFFB_05610	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
XFFB_05625	ENOG4105F8V	Hydrolase, tatD family
XFFB_05665	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
XFFB_05675	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
XFFB_05680	ENOG4108IYU	L-aspartate oxidase
XFFB_05685	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
XFFB_05740	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
XFFB_05745	ENOG4105CV1	Transketolase (EC 2.2.1.1)
XFFB_05750	ENOG4105CK2	sodium dicarboxylate symporter
XFFB_05755	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
XFFB_05775	ENOG4105DGW	oligopeptidase A
XFFB_05785	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
XFFB_05800	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
XFFB_05815	ENOG4105CBS	Chea signal transduction histidine kinase
XFFB_05820	ENOG4105C8Q	Methyl-accepting chemotaxis
XFFB_05825	ENOG4108ZGA	chew protein
XFFB_05830	ENOG4108UNF	response regulator
XFFB_05835	ENOG4105D7Z	glutathione synthase
XFFB_05850	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
XFFB_05855	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
XFFB_05865	ENOG4105PI0	Ferredoxin
XFFB_05885	ENOG4105E2T	synthase III
XFFB_05895	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
XFFB_05900	ENOG4105DC1	bifunctional purine biosynthesis protein purh
XFFB_05905	ENOG4105C12	Phosphoribosylglycinamide synthetase
XFFB_05915	ENOG4105EM2	membrane
XFFB_05920	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
XFFB_05935	ENOG4105EUJ	GTP cyclohydrolase i
XFFB_05940	ENOG4108Z0R	Transferase
XFFB_05945	ENOG4105C2N	RNA methyltransferase TrmH family group 3
XFFB_05965	ENOG4107ZT5	Thiol disulfide interchange protein
XFFB_05970	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
XFFB_05980	ENOG4106WTF	Glycosyl transferase, family 2
XFFB_06000	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
XFFB_06005	ENOG4105CM2	brancheD-chain amino acid aminotransferase
XFFB_06045	ENOG4107RAQ	aminopeptidase
XFFB_06060	ENOG4105W8B	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
XFFB_06070	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
XFFB_06080	ENOG4105E66	phosphoriboisomerase A
XFFB_06090	ENOG4105EEQ	Na H antiporter
XFFB_06105	ENOG4105CJB	Exodeoxyribonuclease I
XFFB_06180	ENOG4105C26	Dehydrogenase
XFFB_06215	ENOG4105CHR	reductase
XFFB_06220	ENOG4105BZS	acriflavin resistance protein
XFFB_06250	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
XFFB_06255	ENOG4105C7I	Dehydrogenase
XFFB_06265	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
XFFB_06270	ENOG4105BZS	acriflavin resistance protein
XFFB_06275	ENOG4108Z0R	Transferase
XFFB_06280	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
XFFB_06300	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
XFFB_06395	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
XFFB_06430	ENOG4105C5H	ABC transporter
XFFB_06435	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
XFFB_06440	ENOG4107ZXU	DSBA oxidoreductase
XFFB_06445	ENOG4107RNH	Outer membrane receptor FepA
XFFB_06455	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
XFFB_06460	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
XFFB_06465	ENOG4105C8U	phosphate abc transporter
XFFB_06470	ENOG4105E2Z	phosphate ABC transporter (Permease
XFFB_06475	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
XFFB_06480	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
XFFB_06485	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
XFFB_06490	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
XFFB_06495	ENOG4105NWN	ApaG protein
XFFB_06500	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
XFFB_06510	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
XFFB_06515	ENOG4105DKP	glycosyl transferase, family 9
XFFB_06530	ENOG4108ZF3	Phosphatase
XFFB_06535	ENOG4107RZZ	dna polymerase iii epsilon subunit
XFFB_06540	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
XFFB_06550	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
XFFB_06555	ENOG4105BZM	domain protein
XFFB_06570	ENOG4105F0N	pyrophosphate phospho-hydrolase
XFFB_06575	ENOG4105K63	Thioredoxin
XFFB_06585	ENOG4105C8T	Leucyl-tRNA synthetase
XFFB_06600	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
XFFB_06620	ENOG4105CVE	Lytic murein transglycosylase
XFFB_06625	ENOG4105K6T	rare lipoprotein A
XFFB_06770	ENOG4105DFP	Integrase
XFFB_06805	ENOG4105KUS	lysozyme
XFFB_06825	ENOG4106FAK	Endodeoxyribonuclease RusA
XFFB_06850	ENOG4108UUM	single-stranded DNA-binding protein
XFFB_06865	ENOG4105C9Q	fumarate hydratase class II
XFFB_06875	ENOG4107QTF	adenylosuccinate lyase
XFFB_06880	ENOG4105EZE	Cupin 4 family protein
XFFB_06885	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
XFFB_06890	ENOG4105C7S	Dehydrogenase
XFFB_06910	ENOG4105CUZ	uba thif-type nad fad binding protein
XFFB_06935	ENOG4105FDS	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
XFFB_06940	ENOG4108S0N	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol (By similarity)
XFFB_06945	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
XFFB_06950	ENOG4108UJD	30S ribosomal protein S9
XFFB_06955	ENOG4105BZN	citrate synthase
XFFB_06960	ENOG4105NRA	50s ribosomal protein l31 type b
XFFB_06965	ENOG41072GX	Peptidase M22 Glycoprotease
XFFB_06970	ENOG4105C5Q	Transcriptional regulator
XFFB_06980	ENOG4105D3R	alkyl hydroperoxide reductase
XFFB_06990	ENOG4105GVR	general secretion pathway protein D
XFFB_07000	ENOG410678M	general secretion pathway protein M
XFFB_07005	ENOG41090VX	general secretion pathway protein L
XFFB_07010	ENOG4105UV2	general secretion pathway protein K
XFFB_07015	ENOG41069G9	General secretion pathway protein J
XFFB_07025	ENOG4105WMT	general secretion pathway protein h
XFFB_07035	ENOG4105D7Q	type ii secretion system
XFFB_07040	ENOG4107QHF	type ii secretion system protein e
XFFB_07045	ENOG4105EUR	Domain-Containing protein
XFFB_07065	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
XFFB_07070	ENOG4108HGY	Proline imino-peptidase
XFFB_07085	ENOG4105CSA	Coproporphyrinogen iii oxidase
XFFB_07090	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
XFFB_07100	ENOG4105DSJ	YicC domain protein
XFFB_07105	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
XFFB_07110	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
XFFB_07120	ENOG4105C11	sulfate adenylyltransferase), subunit 2
XFFB_07130	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
XFFB_07135	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
XFFB_07150	ENOG41063JG	Transcriptional regulator
XFFB_07175	ENOG4105CD8	aminopeptidase N
XFFB_07180	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
XFFB_07190	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
XFFB_07210	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
XFFB_07235	ENOG4105C3K	feS assembly ATPase SufC
XFFB_07245	ENOG4105C9B	Cysteine desulfurase
XFFB_07255	ENOG4107QPH	glycogen) synthase
XFFB_07260	ENOG4107BJW	polysaccharide deacetylase
XFFB_07265	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
XFFB_07270	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
XFFB_07275	ENOG4105CE4	GlcNAc 6-P deacetylase
XFFB_07280	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
XFFB_07285	ENOG4105ETE	Transcriptional regulator (LacI family
XFFB_07300	ENOG4105CHC	glucokinase (EC 2.7.1.2)
XFFB_07315	ENOG4105CAN	Short-chain dehydrogenase reductase Sdr
XFFB_07325	ENOG4105BZU	Histidine kinase
XFFB_07330	ENOG4105WMR	Protein CrcB homolog
XFFB_07335	ENOG4105D1H	recombination factor protein RarA
XFFB_07340	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
XFFB_07350	ENOG4105CNU	cell division protein FtsK
XFFB_07355	ENOG4105C3M	thioredoxin reductase
XFFB_07365	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
XFFB_07370	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
XFFB_07375	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
XFFB_07380	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
XFFB_07395	ENOG41075W9	High frequency lysogenization protein HflD homolog
XFFB_07405	ENOG4108Z33	Thiol disulfide Interchange Protein
XFFB_07410	ENOG4108Z33	Thiol disulfide Interchange Protein
XFFB_07425	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
XFFB_07435	ENOG4105C8Y	Acetylornithine aminotransferase
XFFB_07440	ENOG4105EYW	Ion transport protein
XFFB_07445	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
XFFB_07450	ENOG4105T95	Thiol disulfide interChange protein
XFFB_07490	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
XFFB_07500	ENOG4105C2X	Arabinose 5-phosphate isomerase
XFFB_07505	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
XFFB_07520	ENOG4108IUZ	ABC transporter
XFFB_07525	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
XFFB_07530	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
XFFB_07540	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
XFFB_07550	ENOG41080Z8	PHOSPHOCARRIER protein
XFFB_07555	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
XFFB_07575	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
XFFB_07585	ENOG4105EAH	synthase
XFFB_07590	ENOG4105E2S	oxidase) subunit II
XFFB_07595	ENOG4105BZ9	Cytochrome C oxidase, subunit I
XFFB_07600	ENOG4105CCU	oxidase (Subunit III)
XFFB_07605	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
XFFB_07610	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
XFFB_07635	ENOG4105C9U	ATP-dependent DNA helicase RecQ
XFFB_07645	ENOG4108M8W	Monooxygenase
XFFB_07650	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
XFFB_07655	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
XFFB_07660	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
XFFB_07665	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
XFFB_07670	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
XFFB_07680	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
XFFB_07685	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
XFFB_07690	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
XFFB_07700	ENOG4105DJ4	phosphatidylserine decarboxylase
XFFB_07710	ENOG4107SC1	transglycosylase
XFFB_07715	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
XFFB_07725	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
XFFB_07735	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
XFFB_07740	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
XFFB_07750	ENOG4105NTK	Transcriptional repressor Mpra
XFFB_07755	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
XFFB_07760	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
XFFB_07770	ENOG4108IJ6	ABC transporter
XFFB_07780	ENOG4108I5D	sulfate abc transporter
XFFB_07785	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
XFFB_07805	ENOG4105CX6	glutaminyL-tRNA synthetase
XFFB_07810	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
XFFB_07820	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
XFFB_07825	ENOG4105D49	3-dehydroquinate synthase
XFFB_07830	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
XFFB_07835	ENOG4105BZU	Histidine kinase
XFFB_07840	ENOG4108YYC	ycei family
XFFB_07845	ENOG4108VKM	cytochrome b561
XFFB_07875	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
XFFB_07880	ENOG4107QMS	site-determining protein
XFFB_07900	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
XFFB_07905	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
XFFB_07910	ENOG4105CNI	cell division protein FtsW
XFFB_07915	ENOG4105CJN	penicillin-binding protein
XFFB_07930	ENOG4105DFF	Rod shape-determining protein mreb
XFFB_07975	ENOG4105DHJ	ABC, transporter
XFFB_07980	ENOG4108SNX	Mammalian cell entry related domain protein
XFFB_07995	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
XFFB_08005	ENOG4108DG9	Smr protein MutS2
XFFB_08010	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
XFFB_08015	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
XFFB_08020	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
XFFB_08025	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
XFFB_08030	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
XFFB_08035	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
XFFB_08045	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
XFFB_08070	ENOG4106BRA	Membrane
XFFB_08095	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
XFFB_08100	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
XFFB_08105	ENOG41065HY	1,4-beta-cellobiosidase
XFFB_08125	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
XFFB_08140	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
XFFB_08160	ENOG4105DN3	alpha-2-macroglobulin domain protein
XFFB_08185	ENOG4105C7F	AcnD-accessory protein PrpF
XFFB_08190	ENOG4108I0Z	Aconitate hydratase
XFFB_08290	ENOG4108KU3	Integrase
XFFB_08300	ENOG4105CR4	methylisocitrate lyase
XFFB_08305	ENOG4105MA0	exported protein
XFFB_08310	ENOG4105CFU	surface antigen
XFFB_08320	ENOG4105CQ7	ATP-dependent helicase
XFFB_08340	ENOG4105DA5	(ABC) transporter
XFFB_08345	ENOG4105E3A	(ABC) transporter
XFFB_08350	ENOG4108JJA	ABC, transporter
XFFB_08360	ENOG4108MBX	Secretion Protein
XFFB_08375	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
XFFB_08380	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
XFFB_08385	ENOG4108K3A	Glutathione S-transferase
XFFB_08390	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
XFFB_08415	ENOG4105I08	Pseudouridine synthase
XFFB_08430	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
XFFB_08435	ENOG4107QYD	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
XFFB_08450	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
XFFB_08465	ENOG4105K70	DNA-binding protein
XFFB_08475	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
XFFB_08480	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
XFFB_08485	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
XFFB_08500	ENOG4107QQG	Dehydrogenase
XFFB_08510	ENOG4105MGK	May be involved in the folding of the extracellular lipase during its passage through the periplasm (By similarity)
XFFB_08520	ENOG4105C0P	Mg chelatase subunit ChlI
XFFB_08525	ENOG4105W0Z	cytoplasmic protein
XFFB_08530	ENOG4108ZT0	50S ribosomal protein l17
XFFB_08540	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
XFFB_08545	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
XFFB_08550	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
XFFB_08555	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
XFFB_08560	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
XFFB_08565	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
XFFB_08570	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
XFFB_08575	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
XFFB_08580	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
XFFB_08585	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
XFFB_08590	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
XFFB_08595	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
XFFB_08600	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
XFFB_08605	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
XFFB_08610	ENOG41083MP	50s ribosomal protein l29
XFFB_08620	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
XFFB_08625	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
XFFB_08635	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
XFFB_08640	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
XFFB_08645	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
XFFB_08650	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
XFFB_08660	ENOG4107RAZ	it plays a direct role in the translocation of protons across the membrane (By similarity)
XFFB_08665	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
XFFB_08670	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
XFFB_08675	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
XFFB_08680	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
XFFB_08685	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
XFFB_08690	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
XFFB_08695	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
XFFB_08705	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
XFFB_08720	ENOG4105DQ4	alcohol dehydrogenase
XFFB_08730	ENOG4107ZS6	Flavodoxin
XFFB_08735	ENOG4105CC0	LysR family Transcriptional regulator
XFFB_08745	ENOG4105N42	UPF0307 protein
XFFB_08750	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
XFFB_08760	ENOG4105C03	ribonuclease
XFFB_08765	ENOG4108Z03	MAF-like protein
XFFB_08775	ENOG4105SYT	Methylenetetrahydrofolate reductase
XFFB_08780	ENOG4105M6F	mutator MutT protein
XFFB_08805	ENOG4105E39	Enoyl-CoA hydratase
XFFB_08815	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
XFFB_08825	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
XFFB_08830	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
XFFB_08840	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
XFFB_08850	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
XFFB_08855	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
XFFB_08865	ENOG4105C2M	dna polymerase I
XFFB_08880	ENOG4107RH7	Nicotinate phosphoribosyltransferase
XFFB_08885	ENOG4105CS1	NAD(P)H quinone oxidoreductase
XFFB_08895	ENOG4107RZC	phospholipase d
XFFB_08915	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
XFFB_08920	ENOG4105BZ1	(ABC) transporter
XFFB_08940	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
XFFB_08945	ENOG4105D60	lipoprotein releasing system transmembrane protein
XFFB_08985	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
XFFB_08990	ENOG4108IJ9	(ABC) transporter
XFFB_08995	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
XFFB_09000	ENOG4105CHC	glucokinase (EC 2.7.1.2)
XFFB_09005	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
XFFB_09010	ENOG4105C01	Dihydroxy-acid dehydratase
XFFB_09015	ENOG4108UHU	Aldolase
XFFB_09040	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
XFFB_09065	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
XFFB_09070	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
XFFB_09075	ENOG4105KNE	Phosphatidate cytidylyltransferase
XFFB_09080	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
XFFB_09085	ENOG4105DZP	Membrane-associated zinc metalloprotease
XFFB_09090	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XFFB_09095	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
XFFB_09100	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
XFFB_09105	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
XFFB_09110	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
XFFB_09115	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
XFFB_09125	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
XFFB_09165	ENOG4105C29	acyl-CoA thioesterase
XFFB_09175	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
XFFB_09180	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
XFFB_09185	ENOG4105KST	dependent repressor
XFFB_09190	ENOG4108Z6B	deaminase
XFFB_09195	ENOG4105DDI	hemolysin-type calcium-binding region
XFFB_09240	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
XFFB_09245	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
XFFB_09250	ENOG4105CH7	arginosuccinase
XFFB_09260	ENOG4105CAS	nag kinase
XFFB_09270	ENOG4105CDH	Citrulline--aspartate ligase
XFFB_09275	ENOG4105DBV	ornithine carbamoyltransferase
XFFB_09290	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
XFFB_09295	ENOG4105E8G	Major facilitator Superfamily
XFFB_09305	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
XFFB_09310	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
XFFB_09315	ENOG4105CD3	dihydroorotase
XFFB_09325	ENOG4105BZU	Histidine kinase
XFFB_09335	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
XFFB_09345	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
XFFB_09350	ENOG4106H78	methyltransferase
XFFB_09355	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
XFFB_09360	ENOG4105C6K	Malic enzyme
XFFB_09365	ENOG4105CK2	sodium dicarboxylate symporter
XFFB_09380	ENOG4105BZU	Histidine kinase
XFFB_09485	ENOG4106GZK	Protein of unknown function (DUF2669)
XFFB_09505	ENOG4106GMR	
XFFB_09575	ENOG4105KUS	lysozyme
XFFB_09595	ENOG4106FAK	Endodeoxyribonuclease RusA
XFFB_09710	ENOG4105H40	
XFFB_09715	ENOG4108HJ1	Uncharacterized conserved protein (DUF2303)
XFFB_09730	ENOG4105WXW	Antirepressor
XFFB_09750	ENOG4108UUM	single-stranded DNA-binding protein
XFFB_09765	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
XFFB_09790	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
XFFB_09815	ENOG4107YIM	Involved in the transcription termination process (By similarity)
XFFB_09820	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
XFFB_09825	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
XFFB_09835	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
XFFB_09840	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
XFFB_09850	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
XFFB_09855	ENOG4105C5H	ABC transporter
XFFB_09860	ENOG4105DWT	malate dehydrogenase (quinone)
XFFB_09865	ENOG4105KIR	Thiol-disulfide oxidoreductase dcc
XFFB_09875	ENOG4105C34	Pseudouridine synthase
XFFB_09880	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XFFB_09900	ENOG4105CE1	Ferrous iron transport protein b
XFFB_09915	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
XFFB_09925	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
XFFB_09940	ENOG4105C79	DNA protecting protein DprA
XFFB_09945	ENOG4108RPN	Protein smg homolog
XFFB_09950	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
XFFB_09955	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
XFFB_09990	ENOG4105KB2	stringent starvation protein b
XFFB_09995	ENOG4107MKT	Stringent starvation protein a
XFFB_10000	ENOG4105EIX	cytochrome c1
XFFB_10005	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
XFFB_10010	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
XFFB_10020	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
XFFB_10025	ENOG4105C9A	Phoh family
XFFB_10030	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
XFFB_10040	ENOG4108JU5	Magnesium and cobalt efflux protein
XFFB_10140	ENOG4105BZ4	penicillin-binding protein
XFFB_10160	ENOG41077A9	carbonic anhydrase
XFFB_10175	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
XFFB_10180	ENOG4108UMI	ABC transporter, permease
XFFB_10185	ENOG4105D01	(LipO)protein
XFFB_10195	ENOG4107QSN	dihydrolipoamide acetyltransferase
XFFB_10200	ENOG4107QN2	dihydrolipoyl dehydrogenase
XFFB_10215	ENOG4105C28	cystathionine
XFFB_10220	ENOG4106TYC	homoserine o-acetyltransferase (EC 2.3.1.31)
XFFB_10225	ENOG4105DR5	peptidase
XFFB_10230	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
XFFB_10235	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
XFFB_10240	ENOG4108UM1	dedA family
XFFB_10245	ENOG4108K5P	(LipO)protein
XFFB_10255	ENOG4105BZU	Histidine kinase
XFFB_10260	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
XFFB_10265	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
XFFB_10270	ENOG4105E0X	reductase
XFFB_10275	ENOG4105VRS	hydrolase family 18
XFFB_10315	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
XFFB_10320	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
XFFB_10335	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
XFFB_10340	ENOG4107R11	Transcriptional regulator
XFFB_10375	ENOG4107R1Y	fructose-bisphosphate aldolase
XFFB_10380	ENOG4105CA9	Pyruvate kinase
XFFB_10385	ENOG4105BZA	Phosphoglycerate kinase
XFFB_10390	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
XFFB_10395	ENOG4105MYN	Zinc uptake regulation protein
XFFB_10425	ENOG4108YQE	rare lipoprotein a
XFFB_10430	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
XFFB_10435	ENOG4105DR5	peptidase
XFFB_10445	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
XFFB_10450	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
XFFB_10455	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
XFFB_10460	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
XFFB_10465	ENOG4105CPF	Cell wall formation (By similarity)
XFFB_10470	ENOG4105DFU	Cell wall formation (By similarity)
XFFB_10475	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
XFFB_10485	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
XFFB_10490	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
XFFB_10495	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
XFFB_10500	ENOG4105CJN	penicillin-binding protein
XFFB_10505	ENOG4106932	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
XFFB_10510	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
XFFB_10515	ENOG4108V6E	Cell division protein mraZ
XFFB_10530	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
XFFB_10535	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
XFFB_10540	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
XFFB_10565	ENOG4105EXC	Acyl-transferase
XFFB_10590	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
XFFB_10615	ENOG4107QPB	Beta-lactamase domain protein
XFFB_10620	ENOG41080HT	Transcriptional regulator, arsr family
XFFB_10625	ENOG4105MD1	YeeE YedE family protein
XFFB_10630	ENOG4105KFG	YeeE YedE family protein
XFFB_10635	ENOG4108VCT	Sulfite exporter TauE/SafE
XFFB_10640	ENOG4105DHP	deoxycytidine triphosphate deaminase
XFFB_10650	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
XFFB_10660	ENOG4105K8N	protein family UPF0079, ATPase
XFFB_10675	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
XFFB_10700	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
XFFB_10715	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
XFFB_10720	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
XFFB_10725	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
XFFB_10730	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
XFFB_10740	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
XFFB_10745	ENOG4105C22	threonyL-tRNA synthetase
XFFB_10815	ENOG4105RT5	Toxic component of a toxin-antitoxin (TA) module. An mRNA interferase which has been reported to be translation- independent (PubMed 19690171, PubMed 19943910) and translation- dependent (PubMed 20041169). Cleavage has been reported to occur on either side of G in the sequence GCU (PubMed 19690171) but also after C in GC(A U) sequences (PubMed 19943910). There are only 14 genes in E.coli W3110 (and probably also MG1655) that do not have a GCU sequence and thus are resistant to the mRNA interferase activity. Overexpression causes cessation of cell growth and inhibits cell proliferation via inhibition of translation as well as increasing persister cell formation
XFFB_10820	ENOG4105WJ3	XRE family Transcriptional regulator
XFFB_11040	ENOG4108J6E	Pfam:Phage_integr_N
XFFB_11055	ENOG4105ETX	regulatoR
XFFB_11070	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
XFFB_11090	ENOG4105X0D	Fimbrial protein
XFFB_11095	ENOG4107QHF	type ii secretion system protein e
XFFB_11100	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
XFFB_11105	ENOG4107TUY	Histidine kinase
XFFB_11115	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
XFFB_11120	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
XFFB_11130	ENOG4105D5K	Hemolysin activator protein
XFFB_11140	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
XFFB_11145	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
XFFB_11155	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
XFFB_11165	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
XFFB_11170	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
XFFB_11180	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
XFFB_11185	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
XFFB_11195	ENOG4108Z4V	iron-sulfur cluster assembly
XFFB_11200	ENOG4105C5S	asparaginyl-tRNA synthetase
XFFB_11225	ENOG4105D4A	Cell wall formation (By similarity)
XFFB_11230	ENOG4108SXK	Transporter Drug Metabolite Exporter family
XFFB_11240	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
XFFB_11255	ENOG4108UYB	regulatoR
XFFB_11260	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
XFFB_11275	ENOG4105BZ1	(ABC) transporter
XFFB_11280	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
XFFB_11285	ENOG4105DFG	type I secretion outer membrane protein
XFFB_11290	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
XFFB_11295	ENOG4105C9X	ppx gppa phosphatase
XFFB_11300	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
XFFB_11305	ENOG4105BZU	Histidine kinase
XFFB_11310	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
XFFB_11315	ENOG4105ERG	peptidase m48, ste24p
XFFB_11320	ENOG4105VW4	glutaredoxin 3
XFFB_11325	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
XFFB_11335	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
XFFB_11345	ENOG4108Z4U	Ferredoxin
XFFB_11355	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
XFFB_11360	ENOG41090A4	Pterin carbinolamine dehydratase
XFFB_11375	ENOG4105C03	ribonuclease
XFFB_11385	ENOG4105C72	UPF0176 protein
XFFB_11395	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
XFFB_11410	ENOG4105C5H	ABC transporter
XFFB_11415	ENOG4105CNG	UPF0061 protein
XFFB_11430	ENOG4105D0M	Protease HtpX homolog
XFFB_11435	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
XFFB_11440	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
XFFB_11445	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
XFFB_11450	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
XFFB_11455	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
XFFB_11460	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
XFFB_11465	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
XFFB_11470	ENOG4108VZM	50s ribosomal protein L10
XFFB_11475	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
XFFB_11480	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
XFFB_11485	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
XFFB_11490	ENOG4105PM1	preprotein translocase subunit SecE
XFFB_11500	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
XFFB_11520	ENOG4105C3G	gtp-binding protein
XFFB_11525	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
XFFB_11545	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
XFFB_11550	ENOG4108D76	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
XFFB_11555	ENOG4105DJQ	tetratricopeptide tpr_2 repeat protein
XFFB_11560	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
XFFB_11565	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
XFFB_11600	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
XFFB_11605	ENOG4105M2J	Glutaredoxin
XFFB_11610	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
XFFB_11615	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
XFFB_11620	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
XFFB_11630	ENOG4107STQ	Multicopper oxidase
XFFB_11640	ENOG4105C4R	Atp-dependent dna helicase
XFFB_11650	ENOG4105D07	Signal peptide peptidase, SppA
XFFB_11655	ENOG4107QI1	Mate efflux family protein
XFFB_11670	ENOG4105C25	Primosomal protein n'
XFFB_11680	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
XFFB_11685	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
XFFB_11690	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
XFFB_11695	ENOG4105CAK	Cell division ATP-binding protein ftsE
XFFB_11700	ENOG4105C1J	atp-dependent rna helicase
XFFB_11705	ENOG4105K63	Thioredoxin
XFFB_11710	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
XFFB_11715	ENOG4105E9K	Isocitrate dehydrogenase
XFFB_11725	ENOG4105CN1	protease
XFFB_11730	ENOG41063SB	peptidase
XFFB_11745	ENOG4105BZ8	glutamate synthase
XFFB_11750	ENOG4105CBC	glutamate synthase
XFFB_11755	ENOG4105II7	pyrroline-5-carboxylate reductase
XFFB_11780	ENOG4105UBK	short-chain dehydrogenase reductase
XFFB_11805	ENOG4105DZR	Type I site-specific deoxyribonuclease
XFFB_11855	ENOG410829K	Lysine exporter protein (Lyse ygga)
XFFB_11870	ENOG4105E7D	Protein of unknown function (DUF3375)
XFFB_11900	ENOG4105DZR	Type I site-specific deoxyribonuclease
XFFB_11915	ENOG4105CVR	type I restriction-modification system
XFFB_12015	ENOG4105YES	addiction module antidote protein
XFFB_12020	ENOG4105VUH	addiction module killer protein
XFFB_12075	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
XFFB_12085	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
XFFB_12090	ENOG4107FTS	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)