locus-tag	class	description
Xfasm12_0001	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
Xfasm12_0005	COG0187	DNA topoisomerase II activity
Xfasm12_0007	COG0501	Belongs to the peptidase M48B family
Xfasm12_0021	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
Xfasm12_0037	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
Xfasm12_0039	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
Xfasm12_0041	COG0511	ligase activity, forming carbon-carbon bonds
Xfasm12_0042	COG0439	Biotin carboxylase
Xfasm12_0043	COG0210	DNA helicase
Xfasm12_0049	COG1040	competence protein
Xfasm12_0051	COG1752	Esterase of the alpha-beta hydrolase superfamily
Xfasm12_0055	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
Xfasm12_0057	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
Xfasm12_0064	COG3121	Chaperone
Xfasm12_0065	COG3539	Fimbrial protein
Xfasm12_0067	COG1546	Belongs to the CinA family
Xfasm12_0068	COG0477	Major facilitator Superfamily
Xfasm12_0069	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
Xfasm12_0072	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
Xfasm12_0074	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Xfasm12_0075	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
Xfasm12_0076	COG1534	Rna-binding protein
Xfasm12_0084	COG1560	Kdo2-lipid A biosynthetic process
Xfasm12_0085	COG1519	Transferase
Xfasm12_0089	COG0336	Belongs to the RNA methyltransferase TrmD family
Xfasm12_0091	COG0024	Methionine aminopeptidase
Xfasm12_0094	COG1393	Belongs to the ArsC family
Xfasm12_0096	COG0367	asparagine synthase
Xfasm12_0098	COG2070	2-Nitropropane dioxygenase
Xfasm12_0104	COG0339	signal peptide processing
Xfasm12_0122	COG4221	oxidoreductase activity
Xfasm12_0126	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
Xfasm12_0128	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Xfasm12_0139	COG2223	nitrite transmembrane transporter activity
Xfasm12_0141	COG0739	heme binding
Xfasm12_0143	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
Xfasm12_0146	COG1028	Short-chain dehydrogenase reductase Sdr
Xfasm12_0148	COG1272	protein, Hemolysin III
Xfasm12_0149	COG0463	Glycosyl transferase, family 2
Xfasm12_0150	COG0084	hydrolase, TatD family'
Xfasm12_0157	COG0330	HflC and HflK could
Xfasm12_0158	COG3956	TIGRFAM MazG family protein
Xfasm12_0160	COG0494	nUDIX hydrolase
Xfasm12_0162	COG1385	rRNA (uridine-N3-)-methyltransferase activity
Xfasm12_0163	COG0513	Belongs to the DEAD box helicase family
Xfasm12_0164	COG0720	synthase
Xfasm12_0180	COG0512	Glutamine amidotransferase of anthranilate synthase
Xfasm12_0188	COG0006	proline dipeptidase activity
Xfasm12_0192	COG1862	Preprotein translocase
Xfasm12_0193	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Xfasm12_0194	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Xfasm12_0195	COG0617	tRNA 3'-terminal CCA addition
Xfasm12_0202	COG0195	Participates in both transcription termination and antitermination
Xfasm12_0206	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
Xfasm12_0208	COG1733	regulation of RNA biosynthetic process
Xfasm12_0209	COG0702	epimerase
Xfasm12_0223	COG2086	electron transfer activity
Xfasm12_0229	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Xfasm12_0235	COG0477	Major facilitator Superfamily
Xfasm12_0241	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
Xfasm12_0242	COG0671	phosphoesterase, PA-phosphatase related
Xfasm12_0245	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
Xfasm12_0246	COG0628	permease
Xfasm12_0250	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Xfasm12_0251	COG1090	epimerase
Xfasm12_0252	COG0318	PFAM AMP-dependent synthetase and ligase
Xfasm12_0257	COG1049	propionate catabolic process, 2-methylcitrate cycle
Xfasm12_0265	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Xfasm12_0269	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Xfasm12_0273	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
Xfasm12_0274	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
Xfasm12_0275	COG1034	ATP synthesis coupled electron transport
Xfasm12_0277	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Xfasm12_0282	COG1007	ATP synthesis coupled electron transport
Xfasm12_0283	COG1028	Short-chain dehydrogenase reductase Sdr
Xfasm12_0284	COG2851	Citrate transporter
Xfasm12_0287	COG0642	Histidine kinase
Xfasm12_0291	COG2205	protein histidine kinase activity
Xfasm12_0291	COG0784	Response regulator, receiver
Xfasm12_0295	COG0281	malic enzyme
Xfasm12_0295	COG0280	phosphate acetyltransferase
Xfasm12_0297	COG0742	ribosomal rna small subunit methyltransferase
Xfasm12_0300	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
Xfasm12_0303	COG3706	GGDEF domain
Xfasm12_0305	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
Xfasm12_0307	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
Xfasm12_0310	COG2166	iron-sulfur cluster assembly
Xfasm12_0316	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Xfasm12_0328	COG0590	tRNA wobble adenosine to inosine editing
Xfasm12_0329	COG1321	iron dependent repressor
Xfasm12_0331	COG1914	H( )-stimulated, divalent metal cation uptake system
Xfasm12_0337	COG1946	Acyl-CoA thioesterase
Xfasm12_0358	COG0750	zinc metalloprotease
Xfasm12_0360	COG0575	Belongs to the CDS family
Xfasm12_0361	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
Xfasm12_0368	COG0528	UMP kinase activity
Xfasm12_0374	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
Xfasm12_0376	COG0354	folic acid binding
Xfasm12_0378	COG2009	succinate dehydrogenase
Xfasm12_0379	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
Xfasm12_0381	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
Xfasm12_0387	COG0811	peptide transport
Xfasm12_0405	COG3093	addiction module antidote protein HigA
Xfasm12_0419	COG3772	lysozyme
Xfasm12_0434	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
Xfasm12_0448	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Xfasm12_0448	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Xfasm12_0455	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
Xfasm12_0456	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
Xfasm12_0460	COG1024	Enoyl-CoA hydratase
Xfasm12_0461	COG0527	aspartate kinase activity
Xfasm12_0465	COG0494	nUDIX hydrolase
Xfasm12_0466	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
Xfasm12_0469	COG0424	maF-like protein
Xfasm12_0470	COG1530	ribonuclease E activity
Xfasm12_0472	COG0312	modulator of DNA gyrase
Xfasm12_0474	COG0312	modulator of DNA gyrase
Xfasm12_0475	COG0583	DNA-binding transcription factor activity
Xfasm12_0478	COG1064	alcohol dehydrogenase
Xfasm12_0491	COG0356	it plays a direct role in the translocation of protons across the membrane
Xfasm12_0502	COG0255	Belongs to the universal ribosomal protein uL29 family
Xfasm12_0504	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
Xfasm12_0510	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
Xfasm12_0513	COG0200	Binds to the 23S rRNA
Xfasm12_0514	COG0201	protein transport
Xfasm12_0520	COG2960	long-chain fatty acid transporting porin activity
Xfasm12_0521	COG0606	chelatase, subunit chli
Xfasm12_0525	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
Xfasm12_0532	COG0776	regulation of translation
Xfasm12_0537	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Xfasm12_0538	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Xfasm12_0541	COG1187	pseudouridine synthase activity
Xfasm12_0542	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Xfasm12_0548	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
Xfasm12_0549	COG0625	glutathione transferase activity
Xfasm12_0551	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
Xfasm12_0559	COG0842	Transport permease protein
Xfasm12_0560	COG1131	(ABC) transporter
Xfasm12_0565	COG1643	Atp-dependent helicase
Xfasm12_0567	COG1956	GAF domain-containing protein
Xfasm12_0568	COG0729	surface antigen
Xfasm12_0569	COG2911	Protein conserved in bacteria
Xfasm12_0592	COG0668	transmembrane transport
Xfasm12_0598	COG5297	Belongs to the glycosyl hydrolase family 6
Xfasm12_0600	COG0321	lipoyl(octanoyl) transferase activity
Xfasm12_0606	COG2733	membrane
Xfasm12_0608	COG1253	flavin adenine dinucleotide binding
Xfasm12_0619	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
Xfasm12_0623	COG0644	oxidoreductase
Xfasm12_0623	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
Xfasm12_0626	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
Xfasm12_0626	COG3218	ABC-type transport auxiliary lipoprotein component
Xfasm12_0627	COG1127	ABC transporter
Xfasm12_0628	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
Xfasm12_0633	COG0629	single-stranded DNA binding
Xfasm12_0638	COG4969	Belongs to the N-Me-Phe pilin family
Xfasm12_0659	COG0675	Transposase, IS605 OrfB family
Xfasm12_0668	COG1077	Cell shape determining protein MreB Mrl
Xfasm12_0669	COG1792	Involved in formation and maintenance of cell shape
Xfasm12_0670	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
Xfasm12_0671	COG0768	penicillin binding
Xfasm12_0672	COG0772	Belongs to the SEDS family
Xfasm12_0674	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
Xfasm12_0679	COG2894	cell division
Xfasm12_0684	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
Xfasm12_0687	COG2353	YceI-like domain
Xfasm12_0688	COG0784	Response regulator, receiver
Xfasm12_0688	COG2198	Histidine kinase
Xfasm12_0688	COG2205	protein histidine kinase activity
Xfasm12_0698	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
Xfasm12_0699	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
Xfasm12_0700	COG4208	sulfate ABC transporter
Xfasm12_0706	COG1846	Transcriptional regulator
Xfasm12_0714	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Xfasm12_0716	COG0741	lytic transglycosylase activity
Xfasm12_0724	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
Xfasm12_0732	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Xfasm12_0734	COG0514	ATP-dependent DNA helicase (RecQ)
Xfasm12_0735	COG0783	Belongs to the Dps family
Xfasm12_0736	COG1643	Atp-dependent helicase
Xfasm12_0738	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
Xfasm12_0739	COG1845	cytochrome c oxidase, subunit III
Xfasm12_0740	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
Xfasm12_0741	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
Xfasm12_0742	COG0142	geranyltranstransferase activity
Xfasm12_0743	COG0629	single-stranded DNA binding
Xfasm12_0750	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Xfasm12_0757	COG1137	ATPase activity
Xfasm12_0760	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
Xfasm12_0762	COG0271	Belongs to the BolA IbaG family
Xfasm12_0771	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
Xfasm12_0773	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Xfasm12_0776	COG0218	Necessary for normal cell division and for the maintenance of normal septation
Xfasm12_0780	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
Xfasm12_0786	COG0542	response to heat
Xfasm12_0791	COG0492	ferredoxin-NADP+ reductase activity
Xfasm12_0796	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
Xfasm12_0799	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
Xfasm12_0800	COG1028	Short-chain dehydrogenase reductase Sdr
Xfasm12_0806	COG1609	Transcriptional regulator
Xfasm12_0807	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
Xfasm12_0808	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
Xfasm12_0809	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
Xfasm12_0811	COG0726	polysaccharide deacetylase
Xfasm12_0812	COG0297	glycogen (starch) synthase activity
Xfasm12_0816	COG0719	Fe-S assembly protein
Xfasm12_0817	COG0396	ATPase activity
Xfasm12_0818	COG0719	Fe-S assembly protein
Xfasm12_0819	COG1959	2 iron, 2 sulfur cluster binding
Xfasm12_0830	COG0308	aminopeptidase N
Xfasm12_0839	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
Xfasm12_0844	COG1561	YicC-like family, N-terminal region
Xfasm12_0847	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Xfasm12_0855	COG5295	Hep Hag repeat protein
Xfasm12_0856	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
Xfasm12_0857	COG1459	type II secretion system
Xfasm12_0858	COG2165	general secretion pathway protein
Xfasm12_0859	COG4970	Tfp pilus assembly protein FimT
Xfasm12_0860	COG2165	general secretion pathway protein
Xfasm12_0861	COG4795	General secretion pathway protein
Xfasm12_0862	COG3156	type II secretion system protein K
Xfasm12_0863	COG3166	PFAM Fimbrial assembly family protein
Xfasm12_0866	COG1450	Type ii and iii secretion system protein
Xfasm12_0869	COG0450	alkyl hydroperoxide reductase
Xfasm12_0870	COG3634	alkyl hydroperoxide reductase activity
Xfasm12_0871	COG0583	DNA-binding transcription factor activity
Xfasm12_0873	COG0254	rRNA binding
Xfasm12_0878	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
Xfasm12_0884	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
Xfasm12_0888	COG0508	dehydrogenase complex catalyzes the overall conversion of
Xfasm12_0889	COG0567	Dehydrogenase, E1 component
Xfasm12_0891	COG2850	peptidyl-arginine hydroxylation
Xfasm12_0912	COG3772	lysozyme
Xfasm12_0930	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
Xfasm12_0931	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Xfasm12_0932	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Xfasm12_0934	COG2902	Dehydrogenase
Xfasm12_0942	COG1028	Short-chain dehydrogenase reductase Sdr
Xfasm12_0949	COG1472	Belongs to the glycosyl hydrolase 3 family
Xfasm12_0954	COG2925	Exonuclease
Xfasm12_0957	COG0025	NhaP-type Na H and K H
Xfasm12_0962	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
Xfasm12_0966	COG0006	proline dipeptidase activity
Xfasm12_0968	COG0778	Nitroreductase
Xfasm12_0975	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
Xfasm12_0983	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Xfasm12_0984	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Xfasm12_0986	COG0557	exoribonuclease II activity
Xfasm12_0989	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
Xfasm12_0994	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
Xfasm12_0995	COG1289	transmembrane transporter activity
Xfasm12_1000	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
Xfasm12_1002	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Xfasm12_1007	COG0596	Alpha beta hydrolase
Xfasm12_1011	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Xfasm12_1011	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
Xfasm12_1019	COG0840	transmembrane signaling receptor activity
Xfasm12_1026	COG0285	dihydrofolate synthase activity
Xfasm12_1028	COG0339	signal peptide processing
Xfasm12_1033	COG1301	dicarboxylic acid transport
Xfasm12_1034	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
Xfasm12_1036	COG2091	lysine biosynthetic process via aminoadipic acid
Xfasm12_1039	COG4644	lycopene metabolic process
Xfasm12_1045	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
Xfasm12_1046	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
Xfasm12_1052	COG0084	hydrolase, TatD family'
Xfasm12_1055	COG0552	protein localization to endoplasmic reticulum
Xfasm12_1064	COG0824	Thioesterase
Xfasm12_1069	COG2885	chlorophyll binding
Xfasm12_1071	COG0602	queuosine metabolic process
Xfasm12_1074	COG3104	oligopeptide transport
Xfasm12_1075	COG0386	Belongs to the glutathione peroxidase family
Xfasm12_1079	COG0406	alpha-ribazole phosphatase activity
Xfasm12_1092	COG0582	viral genome integration into host DNA
Xfasm12_1118	COG3852	Histidine kinase
Xfasm12_1119	COG2204	response regulator
Xfasm12_1121	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
Xfasm12_1122	COG0004	ammonium transporteR
Xfasm12_1123	COG0347	Belongs to the P(II) protein family
Xfasm12_1124	COG0174	glutamine synthetase
Xfasm12_1125	COG1968	undecaprenyl-diphosphatase activity
Xfasm12_1126	COG2353	YceI-like domain
Xfasm12_1144	COG3093	addiction module antidote protein HigA
Xfasm12_1158	COG3772	lysozyme
Xfasm12_1185	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
Xfasm12_1195	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
Xfasm12_1196	COG1764	response to oxidative stress
Xfasm12_1198	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Xfasm12_1201	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
Xfasm12_1206	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Xfasm12_1208	COG1399	metal-binding, possibly nucleic acid-binding protein
Xfasm12_1210	COG0714	Associated with various cellular activities
Xfasm12_1214	COG0537	adenosine 5'-monophosphoramidase activity
Xfasm12_1230	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
Xfasm12_1237	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
Xfasm12_1238	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
Xfasm12_1240	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
Xfasm12_1242	COG0251	oxidation-reduction process
Xfasm12_1243	COG0392	lysyltransferase activity
Xfasm12_1243	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
Xfasm12_1245	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Xfasm12_1247	COG0463	Glycosyl transferase, family 2
Xfasm12_1260	COG3275	phosphorelay sensor kinase activity
Xfasm12_1261	COG0400	carboxylic ester hydrolase activity
Xfasm12_1265	COG2226	methyltransferase
Xfasm12_1272	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Xfasm12_1280	COG1131	(ABC) transporter
Xfasm12_1305	COG2369	cell adhesion
Xfasm12_1307	COG5410	chromosome segregation
Xfasm12_1312	COG3772	lysozyme
Xfasm12_1326	COG0489	protein tyrosine kinase activity
Xfasm12_1328	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
Xfasm12_1338	COG0629	single-stranded DNA binding
Xfasm12_1341	COG0488	(ABC) transporter
Xfasm12_1345	COG4651	solute:proton antiporter activity
Xfasm12_1345	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
Xfasm12_1358	COG0859	PFAM glycosyl transferase family 9
Xfasm12_1360	COG0631	protein serine/threonine phosphatase activity
Xfasm12_1361	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
Xfasm12_1362	COG0328	RNA-DNA hybrid ribonuclease activity
Xfasm12_1368	COG2183	response to ionizing radiation
Xfasm12_1372	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
Xfasm12_1374	COG3118	belongs to the thioredoxin family
Xfasm12_1385	COG2951	lytic endotransglycosylase activity
Xfasm12_1386	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
Xfasm12_1406	COG0277	FAD linked oxidase domain protein
Xfasm12_1407	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Xfasm12_1408	COG0531	amino acid
Xfasm12_1409	COG0531	amino acid
Xfasm12_1425	COG0527	aspartate kinase activity
Xfasm12_1425	COG0460	homoserine dehydrogenase
Xfasm12_1426	COG0540	Belongs to the ATCase OTCase family
Xfasm12_1430	COG1686	Belongs to the peptidase S11 family
Xfasm12_1435	COG4953	penicillin-binding protein 1C
Xfasm12_1440	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Xfasm12_1455	COG1506	peptidase
Xfasm12_1455	COG0823	Involved in the tonB-independent uptake of proteins
Xfasm12_1456	COG1297	OPT oligopeptide transporter protein
Xfasm12_1463	COG0676	glucose-6-phosphate 1-epimerase activity
Xfasm12_1466	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
Xfasm12_1467	COG1335	isochorismatase
Xfasm12_1468	COG0318	PFAM AMP-dependent synthetase and ligase
Xfasm12_1470	COG0463	Glycosyl transferase, family 2
Xfasm12_1474	COG1192	Involved in chromosome partitioning
Xfasm12_1487	COG3772	lysozyme
Xfasm12_1497	COG0077	Prephenate dehydratase
Xfasm12_1497	COG1605	Chorismate mutase
Xfasm12_1500	COG1668	transmembrane transport
Xfasm12_1501	COG4555	ABC transporter
Xfasm12_1506	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
Xfasm12_1510	COG0287	Prephenate dehydrogenase
Xfasm12_1510	COG1605	Chorismate mutase
Xfasm12_1514	COG1420	regulation of RNA biosynthetic process
Xfasm12_1515	COG0497	DNA recombination
Xfasm12_1517	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Xfasm12_1518	COG2914	Belongs to the UPF0125 (RnfH) family
Xfasm12_1522	COG1278	Cold shock
Xfasm12_1528	COG0745	RESPONSE REGULATOR receiver
Xfasm12_1529	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
Xfasm12_1533	COG0438	transferase activity, transferring glycosyl groups
Xfasm12_1549	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Xfasm12_1550	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Xfasm12_1551	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Xfasm12_1553	COG1064	alcohol dehydrogenase
Xfasm12_1556	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
Xfasm12_1560	COG3609	addiction module antidote protein, CC2985 family
Xfasm12_1562	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
Xfasm12_1563	COG0675	Transposase, IS605 OrfB family
Xfasm12_1565	COG0436	Aminotransferase
Xfasm12_1579	COG0196	riboflavin kinase activity
Xfasm12_1580	COG0728	peptidoglycan biosynthetic process
Xfasm12_1581	COG0268	Binds directly to 16S ribosomal RNA
Xfasm12_1586	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
Xfasm12_1590	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
Xfasm12_1591	COG1210	Utp--glucose-1-phosphate uridylyltransferase
Xfasm12_1594	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
Xfasm12_1596	COG0776	regulation of translation
Xfasm12_1599	COG0257	Belongs to the bacterial ribosomal protein bL36 family
Xfasm12_1605	COG0395	ABC-type sugar transport system, permease component
Xfasm12_1606	COG1175	transmembrane transport
Xfasm12_1611	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
Xfasm12_1616	COG0436	Aminotransferase
Xfasm12_1617	COG4133	protoheme IX ABC transporter activity
Xfasm12_1621	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
Xfasm12_1623	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Xfasm12_1628	COG5434	Belongs to the glycosyl hydrolase 28 family
Xfasm12_1632	COG0402	S-adenosylhomocysteine deaminase activity
Xfasm12_1634	COG1509	lysine 2,3-aminomutase activity
Xfasm12_1641	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
Xfasm12_1642	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
Xfasm12_1645	COG1028	Short-chain dehydrogenase reductase Sdr
Xfasm12_1651	COG0142	geranyltranstransferase activity
Xfasm12_1653	COG0037	tRNA processing
Xfasm12_1656	COG1301	dicarboxylic acid transport
Xfasm12_1658	COG0791	NLP P60 protein
Xfasm12_1659	COG0791	NLP P60 protein
Xfasm12_1661	COG2311	Membrane
Xfasm12_1665	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
Xfasm12_1688	COG0351	phosphomethylpyrimidine kinase
Xfasm12_1688	COG0352	thiamine-phosphate diphosphorylase activity
Xfasm12_1690	COG1324	tolerance protein
Xfasm12_1700	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Xfasm12_1701	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
Xfasm12_1704	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
Xfasm12_1708	COG4774	siderophore transport
Xfasm12_1713	COG1477	protein flavinylation
Xfasm12_1714	COG1555	photosystem II stabilization
Xfasm12_1715	COG3178	'Phosphotransferase
Xfasm12_1716	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
Xfasm12_1718	COG0628	permease
Xfasm12_1720	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
Xfasm12_1722	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
Xfasm12_1728	COG3590	peptidase
Xfasm12_1742	COG0519	Catalyzes the synthesis of GMP from XMP
Xfasm12_1742	COG0518	GMP synthase (glutamine-hydrolyzing) activity
Xfasm12_1745	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
Xfasm12_1749	COG3107	peptidoglycan biosynthetic process
Xfasm12_1754	COG2878	Part of a membrane complex involved in electron transport
Xfasm12_1770	COG1611	Belongs to the LOG family
Xfasm12_1771	COG4943	cyclic-guanylate-specific phosphodiesterase activity
Xfasm12_1774	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
Xfasm12_1776	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Xfasm12_1782	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
Xfasm12_1786	COG0330	HflC and HflK could
Xfasm12_1787	COG0330	HflC and HflK could
Xfasm12_1788	COG0604	alcohol dehydrogenase
Xfasm12_1796	COG1183	phosphatidylcholine synthase activity
Xfasm12_1801	COG0668	transmembrane transport
Xfasm12_1802	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
Xfasm12_1804	COG0828	Belongs to the bacterial ribosomal protein bS21 family
Xfasm12_1805	COG1610	YqeY-like protein
Xfasm12_1807	COG0358	DNA primase activity
Xfasm12_1814	COG1074	ATP-dependent DNA helicase activity
Xfasm12_1815	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
Xfasm12_1816	COG1127	ABC transporter
Xfasm12_1817	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
Xfasm12_1821	COG2853	Lipoprotein
Xfasm12_1823	COG1322	Protein conserved in bacteria
Xfasm12_1824	COG1116	anion transmembrane transporter activity
Xfasm12_1827	COG0531	amino acid
Xfasm12_1828	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
Xfasm12_1829	COG0861	Integral membrane protein TerC family
Xfasm12_1837	COG2193	ferroxidase activity
Xfasm12_1841	COG2205	protein histidine kinase activity
Xfasm12_1842	COG0745	RESPONSE REGULATOR receiver
Xfasm12_1844	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
Xfasm12_1850	COG0542	response to heat
Xfasm12_1852	COG0352	thiamine-phosphate diphosphorylase activity
Xfasm12_1853	COG2124	cytochrome p450
Xfasm12_1854	COG2194	sulfuric ester hydrolase activity
Xfasm12_1862	COG0667	Aldo Keto reductase
Xfasm12_1863	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Xfasm12_1867	COG0305	Participates in initiation and elongation during chromosome replication
Xfasm12_1872	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
Xfasm12_1874	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
Xfasm12_1878	COG0277	FAD linked oxidase domain protein
Xfasm12_1882	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
Xfasm12_1883	COG4206	TonB-dependent receptor
Xfasm12_1890	COG0675	Transposase, IS605 OrfB family
Xfasm12_1899	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Xfasm12_1903	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
Xfasm12_1908	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Xfasm12_1908	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Xfasm12_1913	COG0488	(ABC) transporter
Xfasm12_1916	COG3011	Protein conserved in bacteria
Xfasm12_1918	COG0564	pseudouridine synthase activity
Xfasm12_1926	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
Xfasm12_1931	COG0758	DNA mediated transformation
Xfasm12_1941	COG2969	positive regulation of protein catabolic process
Xfasm12_1942	COG0625	glutathione transferase activity
Xfasm12_1943	COG2857	Cytochrome c1
Xfasm12_1944	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
Xfasm12_1945	COG0723	plastoquinol--plastocyanin reductase activity
Xfasm12_1946	COG0741	lytic transglycosylase activity
Xfasm12_1948	COG1702	phosphate starvation-inducible protein PhoH
Xfasm12_1951	COG4535	Mg2 and Co2 transporter CorC
Xfasm12_1953	COG0598	Magnesium transport protein CorA
Xfasm12_1965	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Xfasm12_1967	COG1199	ATP-dependent helicase activity
Xfasm12_1969	COG0288	reversible hydration of carbon dioxide
Xfasm12_1975	COG2011	ABC-type metal ion transport system permease component
Xfasm12_1976	COG1464	Belongs to the NlpA lipoprotein family
Xfasm12_1980	COG0508	dehydrogenase complex catalyzes the overall conversion of
Xfasm12_1981	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Xfasm12_1985	COG0626	cystathionine gamma-synthase activity
Xfasm12_1986	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
Xfasm12_1987	COG0739	heme binding
Xfasm12_1994	COG1238	metal cluster binding
Xfasm12_1997	COG5002	protein histidine kinase activity
Xfasm12_2002	COG1388	LysM domain
Xfasm12_2002	COG3858	chitin binding
Xfasm12_2003	COG3525	Glycosyl hydrolase, family 20, catalytic domain
Xfasm12_2005	COG1472	Belongs to the glycosyl hydrolase 3 family
Xfasm12_2008	COG3537	Alpha-1,2-mannosidase
Xfasm12_2014	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Xfasm12_2015	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Xfasm12_2025	COG0469	pyruvate kinase activity
Xfasm12_2029	COG0735	belongs to the Fur family
Xfasm12_2034	COG0612	Peptidase, M16
Xfasm12_2037	COG4305	rare lipoprotein A
Xfasm12_2040	COG0739	heme binding
Xfasm12_2042	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
Xfasm12_2045	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
Xfasm12_2051	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
Xfasm12_2054	COG3116	cell division
Xfasm12_2059	COG0471	metal ion transport
Xfasm12_2059	COG3273	potassium ion transport
Xfasm12_2068	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
Xfasm12_2078	COG0730	response to heat
Xfasm12_2082	COG0860	N-Acetylmuramoyl-L-alanine amidase
Xfasm12_2083	COG0802	atpase or kinase
Xfasm12_2084	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
Xfasm12_2084	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
Xfasm12_2085	COG1570	exodeoxyribonuclease VII activity
Xfasm12_2098	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
Xfasm12_2105	COG0642	Histidine kinase
Xfasm12_2107	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
Xfasm12_2118	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
Xfasm12_2120	COG2831	hemolysin activation secretion protein
Xfasm12_2126	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
Xfasm12_2134	COG0316	Belongs to the HesB IscA family
Xfasm12_2145	COG0697	spore germination
Xfasm12_2146	COG0671	phosphoesterase, PA-phosphatase related
Xfasm12_2147	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
Xfasm12_2149	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
Xfasm12_2150	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
Xfasm12_2153	COG1132	(ABC) transporter
Xfasm12_2155	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
Xfasm12_2156	COG1538	Outer membrane efflux protein
Xfasm12_2163	COG0745	RESPONSE REGULATOR receiver
Xfasm12_2164	COG4783	chaperone-mediated protein folding
Xfasm12_2166	COG0473	3-isopropylmalate dehydrogenase activity
Xfasm12_2168	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
Xfasm12_2169	COG3083	sulfuric ester hydrolase activity
Xfasm12_2170	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
Xfasm12_2175	COG0564	pseudouridine synthase activity
Xfasm12_2176	COG1530	ribonuclease E activity
Xfasm12_2177	COG2197	response regulator
Xfasm12_2185	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
Xfasm12_2186	COG1278	Cold shock
Xfasm12_2188	COG5001	Diguanylate cyclase
Xfasm12_2188	COG4251	negative regulation of phosphorylation
Xfasm12_2188	COG3706	GGDEF domain
Xfasm12_2188	COG2203	Gaf domain
Xfasm12_2191	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
Xfasm12_2194	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
Xfasm12_2200	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
Xfasm12_2201	COG0250	Participates in transcription elongation, termination and antitermination
Xfasm12_2202	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
Xfasm12_2203	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
Xfasm12_2204	COG0012	GTP binding
Xfasm12_2207	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
Xfasm12_2224	COG2095	MarC family integral membrane protein
Xfasm12_2225	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
Xfasm12_2231	COG2132	Multicopper oxidase
Xfasm12_2233	COG0210	DNA helicase
Xfasm12_2235	COG0616	signal peptide processing
Xfasm12_2239	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
Xfasm12_2242	COG2201	protein-glutamate methylesterase activity
Xfasm12_2243	COG2177	Part of the ABC transporter FtsEX involved in
Xfasm12_2244	COG2884	Cell division ATP-binding protein ftsE
Xfasm12_2245	COG0513	Belongs to the DEAD box helicase family
Xfasm12_2247	COG3118	belongs to the thioredoxin family
Xfasm12_2252	COG0793	Belongs to the peptidase S41A family
Xfasm12_2253	COG4942	peptidase
Xfasm12_2256	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
Xfasm12_2257	COG0493	'glutamate synthase
Xfasm12_2258	COG0070	glutamate synthase
Xfasm12_2258	COG0069	glutamate synthase activity
Xfasm12_2258	COG0067	glutamate synthase
Xfasm12_2267	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
Xfasm12_2276	COG1280	lysine exporter protein (LysE YggA)
Xfasm12_2278	COG4942	peptidase
Xfasm12_2283	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
Xfasm12_2302	COG1487	ribonuclease activity
Xfasm12_2303	COG4691	Plasmid stability protein
Xfasm12_2315	COG0594	ribonuclease P activity