locus-tag	class	description
XfasM23_0002	COG0592	DNA-directed DNA polymerase activity
XfasM23_0005	COG0187	DNA topoisomerase II activity
XfasM23_0007	COG0501	Belongs to the peptidase M48B family
XfasM23_0013	COG4946	Tricorn protease homolog
XfasM23_0013	COG0823	Involved in the tonB-independent uptake of proteins
XfasM23_0013	COG1506	peptidase
XfasM23_0017	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
XfasM23_0029	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
XfasM23_0031	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
XfasM23_0033	COG0511	ligase activity, forming carbon-carbon bonds
XfasM23_0034	COG0439	Biotin carboxylase
XfasM23_0035	COG0210	DNA helicase
XfasM23_0040	COG1040	competence protein
XfasM23_0042	COG1752	Esterase of the alpha-beta hydrolase superfamily
XfasM23_0045	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
XfasM23_0047	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
XfasM23_0053	COG3121	Chaperone
XfasM23_0054	COG3539	Fimbrial protein
XfasM23_0055	COG1546	Belongs to the CinA family
XfasM23_0056	COG0477	Major facilitator Superfamily
XfasM23_0057	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
XfasM23_0060	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
XfasM23_0062	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
XfasM23_0064	COG1534	Rna-binding protein
XfasM23_0070	COG1560	Kdo2-lipid A biosynthetic process
XfasM23_0071	COG1519	Transferase
XfasM23_0078	COG0024	Methionine aminopeptidase
XfasM23_0080	COG1393	Belongs to the ArsC family
XfasM23_0082	COG0367	asparagine synthase
XfasM23_0084	COG2070	2-Nitropropane dioxygenase
XfasM23_0089	COG0339	signal peptide processing
XfasM23_0092	COG2132	Multicopper oxidase
XfasM23_0099	COG0795	lipopolysaccharide-transporting ATPase activity
XfasM23_0107	COG4221	oxidoreductase activity
XfasM23_0111	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
XfasM23_0113	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
XfasM23_0122	COG2223	nitrite transmembrane transporter activity
XfasM23_0124	COG0739	heme binding
XfasM23_0126	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
XfasM23_0129	COG1028	Short-chain dehydrogenase reductase Sdr
XfasM23_0131	COG1272	protein, Hemolysin III
XfasM23_0132	COG0463	Glycosyl transferase, family 2
XfasM23_0133	COG0084	hydrolase, TatD family'
XfasM23_0138	COG0330	HflC and HflK could
XfasM23_0139	COG3956	TIGRFAM MazG family protein
XfasM23_0140	COG1218	3'(2'),5'-bisphosphate nucleotidase
XfasM23_0141	COG0494	nUDIX hydrolase
XfasM23_0143	COG1385	rRNA (uridine-N3-)-methyltransferase activity
XfasM23_0145	COG0513	Belongs to the DEAD box helicase family
XfasM23_0146	COG0720	synthase
XfasM23_0158	COG0512	Glutamine amidotransferase of anthranilate synthase
XfasM23_0164	COG0006	proline dipeptidase activity
XfasM23_0168	COG1862	Preprotein translocase
XfasM23_0169	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
XfasM23_0170	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
XfasM23_0171	COG0617	tRNA 3'-terminal CCA addition
XfasM23_0178	COG0195	Participates in both transcription termination and antitermination
XfasM23_0184	COG1733	regulation of RNA biosynthetic process
XfasM23_0185	COG0702	epimerase
XfasM23_0194	COG2086	electron transfer activity
XfasM23_0200	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
XfasM23_0207	COG0477	Major facilitator Superfamily
XfasM23_0211	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
XfasM23_0212	COG0671	phosphoesterase, PA-phosphatase related
XfasM23_0215	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
XfasM23_0216	COG0628	permease
XfasM23_0220	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XfasM23_0221	COG1090	epimerase
XfasM23_0222	COG0318	PFAM AMP-dependent synthetase and ligase
XfasM23_0227	COG1049	propionate catabolic process, 2-methylcitrate cycle
XfasM23_0230	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
XfasM23_0236	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XfasM23_0240	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XfasM23_0244	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
XfasM23_0245	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
XfasM23_0246	COG1034	ATP synthesis coupled electron transport
XfasM23_0248	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XfasM23_0253	COG1007	ATP synthesis coupled electron transport
XfasM23_0254	COG1028	Short-chain dehydrogenase reductase Sdr
XfasM23_0255	COG2851	Citrate transporter
XfasM23_0258	COG0642	Histidine kinase
XfasM23_0262	COG0784	Response regulator, receiver
XfasM23_0262	COG2205	protein histidine kinase activity
XfasM23_0265	COG0280	phosphate acetyltransferase
XfasM23_0265	COG0281	malic enzyme
XfasM23_0267	COG0742	ribosomal rna small subunit methyltransferase
XfasM23_0270	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
XfasM23_0272	COG3706	GGDEF domain
XfasM23_0274	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
XfasM23_0276	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
XfasM23_0280	COG2166	iron-sulfur cluster assembly
XfasM23_0286	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XfasM23_0300	COG0590	tRNA wobble adenosine to inosine editing
XfasM23_0301	COG1321	iron dependent repressor
XfasM23_0306	COG1946	Acyl-CoA thioesterase
XfasM23_0325	COG0575	Belongs to the CDS family
XfasM23_0340	COG0354	folic acid binding
XfasM23_0342	COG2009	succinate dehydrogenase
XfasM23_0343	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
XfasM23_0345	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
XfasM23_0351	COG0811	peptide transport
XfasM23_0361	COG3093	addiction module antidote protein HigA
XfasM23_0363	COG2944	sequence-specific DNA binding
XfasM23_0376	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
XfasM23_0380	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XfasM23_0396	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
XfasM23_0397	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
XfasM23_0401	COG1024	Enoyl-CoA hydratase
XfasM23_0402	COG0019	diaminopimelate decarboxylase activity
XfasM23_0405	COG0494	nUDIX hydrolase
XfasM23_0406	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
XfasM23_0409	COG1530	ribonuclease E activity
XfasM23_0412	COG0312	modulator of DNA gyrase
XfasM23_0414	COG0312	modulator of DNA gyrase
XfasM23_0415	COG0583	DNA-binding transcription factor activity
XfasM23_0418	COG1064	alcohol dehydrogenase
XfasM23_0430	COG0356	it plays a direct role in the translocation of protons across the membrane
XfasM23_0453	COG0201	protein transport
XfasM23_0459	COG2960	long-chain fatty acid transporting porin activity
XfasM23_0460	COG0606	chelatase, subunit chli
XfasM23_0464	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
XfasM23_0474	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
XfasM23_0475	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
XfasM23_0478	COG1187	pseudouridine synthase activity
XfasM23_0479	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
XfasM23_0483	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XfasM23_0484	COG0625	glutathione transferase activity
XfasM23_0486	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
XfasM23_0495	COG0842	Transport permease protein
XfasM23_0496	COG1131	(ABC) transporter
XfasM23_0501	COG1643	Atp-dependent helicase
XfasM23_0503	COG1956	GAF domain-containing protein
XfasM23_0504	COG0729	surface antigen
XfasM23_0505	COG2911	Protein conserved in bacteria
XfasM23_0534	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
XfasM23_0547	COG0668	transmembrane transport
XfasM23_0553	COG5297	Belongs to the glycosyl hydrolase family 6
XfasM23_0561	COG2733	membrane
XfasM23_0562	COG1253	flavin adenine dinucleotide binding
XfasM23_0574	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
XfasM23_0574	COG0644	oxidoreductase
XfasM23_0577	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
XfasM23_0577	COG3218	ABC-type transport auxiliary lipoprotein component
XfasM23_0578	COG1127	ABC transporter
XfasM23_0579	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
XfasM23_0587	COG1077	Cell shape determining protein MreB Mrl
XfasM23_0588	COG1792	Involved in formation and maintenance of cell shape
XfasM23_0589	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
XfasM23_0590	COG0768	penicillin binding
XfasM23_0591	COG0772	Belongs to the SEDS family
XfasM23_0593	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
XfasM23_0597	COG2894	cell division
XfasM23_0601	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
XfasM23_0604	COG2353	YceI-like domain
XfasM23_0619	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
XfasM23_0620	COG4208	sulfate ABC transporter
XfasM23_0625	COG1846	Transcriptional regulator
XfasM23_0633	COG0741	lytic transglycosylase activity
XfasM23_0635	COG1999	signal sequence binding
XfasM23_0640	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
XfasM23_0647	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XfasM23_0649	COG0514	ATP-dependent DNA helicase (RecQ)
XfasM23_0650	COG0783	Belongs to the Dps family
XfasM23_0651	COG1643	Atp-dependent helicase
XfasM23_0653	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
XfasM23_0654	COG1845	cytochrome c oxidase, subunit III
XfasM23_0655	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
XfasM23_0656	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
XfasM23_0657	COG0142	geranyltranstransferase activity
XfasM23_0660	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
XfasM23_0664	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
XfasM23_0671	COG1137	ATPase activity
XfasM23_0674	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
XfasM23_0676	COG0271	Belongs to the BolA IbaG family
XfasM23_0683	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
XfasM23_0685	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XfasM23_0693	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
XfasM23_0699	COG0542	response to heat
XfasM23_0703	COG0492	ferredoxin-NADP+ reductase activity
XfasM23_0707	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
XfasM23_0709	COG4191	Histidine kinase
XfasM23_0710	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
XfasM23_0711	COG1028	Short-chain dehydrogenase reductase Sdr
XfasM23_0717	COG1609	Transcriptional regulator
XfasM23_0718	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
XfasM23_0719	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
XfasM23_0720	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
XfasM23_0722	COG0726	polysaccharide deacetylase
XfasM23_0723	COG0297	glycogen (starch) synthase activity
XfasM23_0727	COG0719	Fe-S assembly protein
XfasM23_0728	COG0396	ATPase activity
XfasM23_0729	COG0719	Fe-S assembly protein
XfasM23_0730	COG1959	2 iron, 2 sulfur cluster binding
XfasM23_0741	COG0308	aminopeptidase N
XfasM23_0752	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
XfasM23_0757	COG1561	YicC-like family, N-terminal region
XfasM23_0760	COG0635	Involved in the biosynthesis of porphyrin-containing compound
XfasM23_0768	COG5295	Hep Hag repeat protein
XfasM23_0769	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
XfasM23_0770	COG1459	type II secretion system
XfasM23_0771	COG2165	general secretion pathway protein
XfasM23_0772	COG4970	Tfp pilus assembly protein FimT
XfasM23_0773	COG2165	general secretion pathway protein
XfasM23_0774	COG4795	General secretion pathway protein
XfasM23_0775	COG3156	type II secretion system protein K
XfasM23_0776	COG3166	PFAM Fimbrial assembly family protein
XfasM23_0779	COG1450	Type ii and iii secretion system protein
XfasM23_0781	COG0450	alkyl hydroperoxide reductase
XfasM23_0782	COG3634	alkyl hydroperoxide reductase activity
XfasM23_0783	COG0583	DNA-binding transcription factor activity
XfasM23_0797	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
XfasM23_0803	COG0567	Dehydrogenase, E1 component
XfasM23_0804	COG2850	peptidyl-arginine hydroxylation
XfasM23_0808	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
XfasM23_0826	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
XfasM23_0827	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XfasM23_0828	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XfasM23_0829	COG2902	Dehydrogenase
XfasM23_0837	COG2925	Exonuclease
XfasM23_0840	COG0025	NhaP-type Na H and K H
XfasM23_0844	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
XfasM23_0848	COG0006	proline dipeptidase activity
XfasM23_0850	COG0778	Nitroreductase
XfasM23_0857	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
XfasM23_0866	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XfasM23_0868	COG0557	exoribonuclease II activity
XfasM23_0870	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
XfasM23_0873	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
XfasM23_0874	COG1289	transmembrane transporter activity
XfasM23_0879	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
XfasM23_0881	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XfasM23_0885	COG0596	Alpha beta hydrolase
XfasM23_0895	COG0840	transmembrane signaling receptor activity
XfasM23_0902	COG0285	dihydrofolate synthase activity
XfasM23_0904	COG0339	signal peptide processing
XfasM23_0909	COG1301	dicarboxylic acid transport
XfasM23_0910	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
XfasM23_0912	COG2091	lysine biosynthetic process via aminoadipic acid
XfasM23_0923	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
XfasM23_0932	COG0084	hydrolase, TatD family'
XfasM23_0936	COG0552	protein localization to endoplasmic reticulum
XfasM23_0945	COG0824	Thioesterase
XfasM23_0950	COG2885	chlorophyll binding
XfasM23_0952	COG0602	queuosine metabolic process
XfasM23_0955	COG3104	oligopeptide transport
XfasM23_0956	COG0386	Belongs to the glutathione peroxidase family
XfasM23_0960	COG0406	alpha-ribazole phosphatase activity
XfasM23_1005	COG0675	Transposase, IS605 OrfB family
XfasM23_1037	COG2369	cell adhesion
XfasM23_1044	COG3210	domain, Protein
XfasM23_1046	COG0582	viral genome integration into host DNA
XfasM23_1047	COG3567	Phage-associated protein, HI1409 family
XfasM23_1048	COG5410	chromosome segregation
XfasM23_1053	COG3772	lysozyme
XfasM23_1060	COG3617	BRO family, N-terminal domain
XfasM23_1076	COG5532	Uncharacterized conserved protein (DUF2303)
XfasM23_1081	COG0629	single-stranded DNA binding
XfasM23_1083	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
XfasM23_1084	COG3852	Histidine kinase
XfasM23_1085	COG2204	response regulator
XfasM23_1087	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
XfasM23_1088	COG0004	ammonium transporteR
XfasM23_1089	COG0347	Belongs to the P(II) protein family
XfasM23_1090	COG0174	glutamine synthetase
XfasM23_1092	COG2353	YceI-like domain
XfasM23_1103	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
XfasM23_1104	COG1764	response to oxidative stress
XfasM23_1105	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XfasM23_1114	COG1399	metal-binding, possibly nucleic acid-binding protein
XfasM23_1116	COG0714	Associated with various cellular activities
XfasM23_1120	COG0537	adenosine 5'-monophosphoramidase activity
XfasM23_1123	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
XfasM23_1131	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
XfasM23_1136	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
XfasM23_1136	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
XfasM23_1145	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
XfasM23_1148	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
XfasM23_1150	COG0251	oxidation-reduction process
XfasM23_1163	COG3077	Addiction module antitoxin, RelB DinJ family
XfasM23_1164	COG3041	Addiction module toxin RelE StbE family
XfasM23_1178	COG3772	lysozyme
XfasM23_1191	COG4197	protein conserved in bacteria, prophage-related
XfasM23_1205	COG3617	BRO family, N-terminal domain
XfasM23_1212	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
XfasM23_1213	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
XfasM23_1213	COG0392	lysyltransferase activity
XfasM23_1215	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
XfasM23_1217	COG0463	Glycosyl transferase, family 2
XfasM23_1227	COG3275	phosphorelay sensor kinase activity
XfasM23_1228	COG0400	carboxylic ester hydrolase activity
XfasM23_1232	COG2226	methyltransferase
XfasM23_1240	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XfasM23_1246	COG0386	Belongs to the glutathione peroxidase family
XfasM23_1247	COG1131	(ABC) transporter
XfasM23_1253	COG3657	addiction module killer protein
XfasM23_1254	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
XfasM23_1266	COG0675	Transposase, IS605 OrfB family
XfasM23_1275	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
XfasM23_1276	COG0488	(ABC) transporter
XfasM23_1278	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
XfasM23_1281	COG4651	solute:proton antiporter activity
XfasM23_1281	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
XfasM23_1293	COG0859	PFAM glycosyl transferase family 9
XfasM23_1295	COG0631	protein serine/threonine phosphatase activity
XfasM23_1296	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
XfasM23_1303	COG2183	response to ionizing radiation
XfasM23_1306	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
XfasM23_1307	COG3118	belongs to the thioredoxin family
XfasM23_1315	COG2951	lytic endotransglycosylase activity
XfasM23_1316	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
XfasM23_1339	COG0277	FAD linked oxidase domain protein
XfasM23_1340	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
XfasM23_1341	COG0531	amino acid
XfasM23_1342	COG0531	amino acid
XfasM23_1358	COG0460	homoserine dehydrogenase
XfasM23_1358	COG0527	aspartate kinase activity
XfasM23_1362	COG1686	Belongs to the peptidase S11 family
XfasM23_1366	COG4953	penicillin-binding protein 1C
XfasM23_1371	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XfasM23_1384	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XfasM23_1385	COG1506	peptidase
XfasM23_1385	COG0823	Involved in the tonB-independent uptake of proteins
XfasM23_1386	COG1297	OPT oligopeptide transporter protein
XfasM23_1391	COG0676	glucose-6-phosphate 1-epimerase activity
XfasM23_1393	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
XfasM23_1394	COG1335	isochorismatase
XfasM23_1395	COG0318	PFAM AMP-dependent synthetase and ligase
XfasM23_1397	COG0463	Glycosyl transferase, family 2
XfasM23_1400	COG1192	Involved in chromosome partitioning
XfasM23_1411	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
XfasM23_1420	COG0489	protein tyrosine kinase activity
XfasM23_1422	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
XfasM23_1442	COG0077	Prephenate dehydratase
XfasM23_1442	COG1605	Chorismate mutase
XfasM23_1445	COG1668	transmembrane transport
XfasM23_1446	COG4555	ABC transporter
XfasM23_1451	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
XfasM23_1453	COG0287	Prephenate dehydrogenase
XfasM23_1453	COG1605	Chorismate mutase
XfasM23_1460	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XfasM23_1465	COG1278	Cold shock
XfasM23_1473	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
XfasM23_1477	COG0438	transferase activity, transferring glycosyl groups
XfasM23_1488	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XfasM23_1489	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XfasM23_1492	COG1064	alcohol dehydrogenase
XfasM23_1496	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
XfasM23_1498	COG0436	Aminotransferase
XfasM23_1514	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XfasM23_1514	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
XfasM23_1522	COG0196	riboflavin kinase activity
XfasM23_1523	COG0728	peptidoglycan biosynthetic process
XfasM23_1524	COG0268	Binds directly to 16S ribosomal RNA
XfasM23_1534	COG1210	Utp--glucose-1-phosphate uridylyltransferase
XfasM23_1537	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
XfasM23_1548	COG0395	ABC-type sugar transport system, permease component
XfasM23_1549	COG1175	transmembrane transport
XfasM23_1555	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
XfasM23_1559	COG0436	Aminotransferase
XfasM23_1570	COG5434	Belongs to the glycosyl hydrolase 28 family
XfasM23_1575	COG0402	S-adenosylhomocysteine deaminase activity
XfasM23_1577	COG1509	lysine 2,3-aminomutase activity
XfasM23_1584	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
XfasM23_1585	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
XfasM23_1588	COG1028	Short-chain dehydrogenase reductase Sdr
XfasM23_1599	COG0142	geranyltranstransferase activity
XfasM23_1603	COG1301	dicarboxylic acid transport
XfasM23_1605	COG0791	NLP P60 protein
XfasM23_1606	COG0791	NLP P60 protein
XfasM23_1608	COG2311	Membrane
XfasM23_1610	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
XfasM23_1619	COG0352	thiamine-phosphate diphosphorylase activity
XfasM23_1619	COG0351	phosphomethylpyrimidine kinase
XfasM23_1621	COG1324	tolerance protein
XfasM23_1628	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XfasM23_1629	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XfasM23_1630	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
XfasM23_1633	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
XfasM23_1637	COG4774	siderophore transport
XfasM23_1642	COG1477	protein flavinylation
XfasM23_1644	COG1555	photosystem II stabilization
XfasM23_1645	COG3178	'Phosphotransferase
XfasM23_1646	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
XfasM23_1648	COG0628	permease
XfasM23_1651	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
XfasM23_1657	COG3590	peptidase
XfasM23_1670	COG0518	GMP synthase (glutamine-hydrolyzing) activity
XfasM23_1670	COG0519	Catalyzes the synthesis of GMP from XMP
XfasM23_1672	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
XfasM23_1675	COG3107	peptidoglycan biosynthetic process
XfasM23_1680	COG2878	Part of a membrane complex involved in electron transport
XfasM23_1691	COG0358	DNA primase activity
XfasM23_1694	COG0629	single-stranded DNA binding
XfasM23_1700	COG0827	DNA restriction-modification system
XfasM23_1701	COG0827	DNA restriction-modification system
XfasM23_1707	COG4968	Prepilin-type N-terminal cleavage methylation domain
XfasM23_1708	COG1611	Belongs to the LOG family
XfasM23_1709	COG4943	cyclic-guanylate-specific phosphodiesterase activity
XfasM23_1710	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
XfasM23_1712	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XfasM23_1718	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
XfasM23_1721	COG0330	HflC and HflK could
XfasM23_1722	COG0330	HflC and HflK could
XfasM23_1723	COG0604	alcohol dehydrogenase
XfasM23_1729	COG1183	phosphatidylcholine synthase activity
XfasM23_1733	COG0668	transmembrane transport
XfasM23_1734	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
XfasM23_1737	COG1610	YqeY-like protein
XfasM23_1739	COG0358	DNA primase activity
XfasM23_1746	COG1074	ATP-dependent DNA helicase activity
XfasM23_1747	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
XfasM23_1748	COG1127	ABC transporter
XfasM23_1749	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
XfasM23_1753	COG2853	Lipoprotein
XfasM23_1756	COG1116	anion transmembrane transporter activity
XfasM23_1760	COG0531	amino acid
XfasM23_1761	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
XfasM23_1762	COG0861	Integral membrane protein TerC family
XfasM23_1768	COG2193	ferroxidase activity
XfasM23_1772	COG2205	protein histidine kinase activity
XfasM23_1773	COG0745	RESPONSE REGULATOR receiver
XfasM23_1783	COG2194	sulfuric ester hydrolase activity
XfasM23_1791	COG0667	Aldo Keto reductase
XfasM23_1792	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XfasM23_1794	COG0305	Participates in initiation and elongation during chromosome replication
XfasM23_1798	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
XfasM23_1800	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
XfasM23_1801	COG0277	FAD linked oxidase domain protein
XfasM23_1806	COG4206	TonB-dependent receptor
XfasM23_1825	COG3617	BRO family, N-terminal domain
XfasM23_1838	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
XfasM23_1840	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
XfasM23_1843	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
XfasM23_1848	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
XfasM23_1848	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
XfasM23_1852	COG0488	(ABC) transporter
XfasM23_1854	COG3011	Protein conserved in bacteria
XfasM23_1860	COG1918	ferrous iron import across plasma membrane
XfasM23_1860	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
XfasM23_1862	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
XfasM23_1867	COG0758	DNA mediated transformation
XfasM23_1876	COG2969	positive regulation of protein catabolic process
XfasM23_1877	COG0625	glutathione transferase activity
XfasM23_1878	COG2857	Cytochrome c1
XfasM23_1879	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
XfasM23_1880	COG0723	plastoquinol--plastocyanin reductase activity
XfasM23_1881	COG0741	lytic transglycosylase activity
XfasM23_1883	COG1702	phosphate starvation-inducible protein PhoH
XfasM23_1886	COG4535	Mg2 and Co2 transporter CorC
XfasM23_1888	COG0598	Magnesium transport protein CorA
XfasM23_1895	COG3210	domain, Protein
XfasM23_1895	COG3210	domain, Protein
XfasM23_1899	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
XfasM23_1901	COG1199	ATP-dependent helicase activity
XfasM23_1903	COG0288	reversible hydration of carbon dioxide
XfasM23_1907	COG2011	ABC-type metal ion transport system permease component
XfasM23_1910	COG0508	dehydrogenase complex catalyzes the overall conversion of
XfasM23_1911	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XfasM23_1914	COG0626	cystathionine gamma-synthase activity
XfasM23_1915	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XfasM23_1916	COG0739	heme binding
XfasM23_1920	COG1238	metal cluster binding
XfasM23_1922	COG5002	protein histidine kinase activity
XfasM23_1926	COG3858	chitin binding
XfasM23_1926	COG1388	LysM domain
XfasM23_1927	COG3525	Glycosyl hydrolase, family 20, catalytic domain
XfasM23_1929	COG1472	Belongs to the glycosyl hydrolase 3 family
XfasM23_1932	COG3537	Alpha-1,2-mannosidase
XfasM23_1937	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XfasM23_1938	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XfasM23_1948	COG0469	pyruvate kinase activity
XfasM23_1951	COG0735	belongs to the Fur family
XfasM23_1953	COG5297	Belongs to the glycosyl hydrolase family 6
XfasM23_1953	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XfasM23_1958	COG4305	rare lipoprotein A
XfasM23_1960	COG0739	heme binding
XfasM23_1964	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
XfasM23_1966	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
XfasM23_1972	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
XfasM23_1975	COG3116	cell division
XfasM23_1981	COG0471	metal ion transport
XfasM23_1981	COG3273	potassium ion transport
XfasM23_1991	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
XfasM23_2003	COG0860	N-Acetylmuramoyl-L-alanine amidase
XfasM23_2004	COG0802	atpase or kinase
XfasM23_2005	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
XfasM23_2005	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
XfasM23_2026	COG0745	RESPONSE REGULATOR receiver
XfasM23_2027	COG0642	Histidine kinase
XfasM23_2029	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
XfasM23_2038	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
XfasM23_2040	COG2831	hemolysin activation secretion protein
XfasM23_2045	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
XfasM23_2053	COG0316	Belongs to the HesB IscA family
XfasM23_2060	COG0697	spore germination
XfasM23_2061	COG0671	phosphoesterase, PA-phosphatase related
XfasM23_2064	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
XfasM23_2067	COG1132	(ABC) transporter
XfasM23_2068	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
XfasM23_2069	COG1538	Outer membrane efflux protein
XfasM23_2074	COG0745	RESPONSE REGULATOR receiver
XfasM23_2075	COG4783	chaperone-mediated protein folding
XfasM23_2077	COG0473	3-isopropylmalate dehydrogenase activity
XfasM23_2079	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
XfasM23_2080	COG3083	sulfuric ester hydrolase activity
XfasM23_2082	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
XfasM23_2087	COG0564	pseudouridine synthase activity
XfasM23_2088	COG1530	ribonuclease E activity
XfasM23_2089	COG2197	response regulator
XfasM23_2098	COG1278	Cold shock
XfasM23_2104	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
XfasM23_2115	COG0012	GTP binding
XfasM23_2133	COG2095	MarC family integral membrane protein
XfasM23_2134	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
XfasM23_2141	COG2132	Multicopper oxidase
XfasM23_2143	COG0210	DNA helicase
XfasM23_2145	COG0616	signal peptide processing
XfasM23_2149	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
XfasM23_2153	COG2201	protein-glutamate methylesterase activity
XfasM23_2154	COG2177	Part of the ABC transporter FtsEX involved in
XfasM23_2155	COG2884	Cell division ATP-binding protein ftsE
XfasM23_2157	COG3118	belongs to the thioredoxin family
XfasM23_2158	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
XfasM23_2160	COG0793	Belongs to the peptidase S41A family
XfasM23_2161	COG4942	peptidase
XfasM23_2164	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XfasM23_2165	COG0493	'glutamate synthase
XfasM23_2166	COG0069	glutamate synthase activity
XfasM23_2166	COG0067	glutamate synthase
XfasM23_2166	COG0070	glutamate synthase
XfasM23_2175	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
XfasM23_2185	COG4942	peptidase
XfasM23_2207	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
XfasM23_2208	COG3657	addiction module killer protein
XfasM23_2221	COG3210	domain, Protein
XfasM23_2228	COG3451	type IV secretory pathway VirB4
XfasM23_2239	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
XfasM23_2259	COG0675	Transposase, IS605 OrfB family
XfasM23_2263	COG0629	single-stranded DNA binding
XfasM23_2265	COG4962	Type ii secretion system protein e