locus-tag	class	description
BCV75_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BCV75_00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BCV75_00025	COG0187	DNA topoisomerase II activity
BCV75_00035	COG0501	Belongs to the peptidase M48B family
BCV75_00075	COG0408	coproporphyrinogen oxidase activity
BCV75_00090	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BCV75_00105	COG4969	Belongs to the N-Me-Phe pilin family
BCV75_00135	COG0284	orotidine-5'-phosphate decarboxylase activity
BCV75_00160	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
BCV75_00170	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BCV75_00180	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BCV75_00185	COG0511	ligase activity, forming carbon-carbon bonds
BCV75_00190	COG0439	Biotin carboxylase
BCV75_00195	COG0210	DNA helicase
BCV75_00205	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BCV75_00205	COG1017	nitric oxide dioxygenase activity
BCV75_00215	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
BCV75_00225	COG1040	competence protein
BCV75_00230	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BCV75_00235	COG1752	Esterase of the alpha-beta hydrolase superfamily
BCV75_00240	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BCV75_00275	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BCV75_00285	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BCV75_00320	COG3121	Chaperone
BCV75_00325	COG3539	Fimbrial protein
BCV75_00330	COG1546	Belongs to the CinA family
BCV75_00335	COG0477	Major facilitator Superfamily
BCV75_00340	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BCV75_00345	COG1923	regulation of RNA biosynthetic process
BCV75_00350	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BCV75_00355	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BCV75_00365	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BCV75_00370	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
BCV75_00375	COG1534	Rna-binding protein
BCV75_00405	COG1560	Kdo2-lipid A biosynthetic process
BCV75_00420	COG0228	four-way junction DNA binding
BCV75_00425	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BCV75_00430	COG0336	Belongs to the RNA methyltransferase TrmD family
BCV75_00435	COG0335	large ribosomal subunit rRNA binding
BCV75_00440	COG0024	Methionine aminopeptidase
BCV75_00445	COG2171	N-acyltransferase activity
BCV75_00450	COG1393	Belongs to the ArsC family
BCV75_00455	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BCV75_00460	COG0367	asparagine synthase
BCV75_00470	COG2070	2-Nitropropane dioxygenase
BCV75_00480	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BCV75_00485	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BCV75_00500	COG0339	signal peptide processing
BCV75_00525	COG0525	valine-tRNA ligase activity
BCV75_00565	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BCV75_00575	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BCV75_00585	COG4221	oxidoreductase activity
BCV75_00605	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BCV75_00615	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BCV75_00625	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BCV75_00655	COG2223	nitrite transmembrane transporter activity
BCV75_00660	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
BCV75_00665	COG0739	heme binding
BCV75_00670	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BCV75_00700	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BCV75_00720	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BCV75_00725	COG1272	protein, Hemolysin III
BCV75_00730	COG0463	Glycosyl transferase, family 2
BCV75_00735	COG0084	hydrolase, TatD family'
BCV75_00750	COG0509	glycine decarboxylation via glycine cleavage system
BCV75_00755	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BCV75_00770	COG3956	TIGRFAM MazG family protein
BCV75_00775	COG1218	3'(2'),5'-bisphosphate nucleotidase
BCV75_00780	COG0494	nUDIX hydrolase
BCV75_00790	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BCV75_00795	COG0513	Belongs to the DEAD box helicase family
BCV75_00800	COG0720	synthase
BCV75_00830	COG0825	malonyl-CoA metabolic process
BCV75_00835	COG0587	DNA-directed DNA polymerase activity
BCV75_00860	COG0512	Glutamine amidotransferase of anthranilate synthase
BCV75_00865	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BCV75_00870	COG0134	indole-3-glycerol-phosphate synthase activity
BCV75_00890	COG0006	proline dipeptidase activity
BCV75_00905	COG0343	queuine tRNA-ribosyltransferase activity
BCV75_00910	COG1862	Preprotein translocase
BCV75_00915	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BCV75_00930	COG0617	tRNA 3'-terminal CCA addition
BCV75_00940	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BCV75_00945	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BCV75_00950	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
BCV75_00955	COG0166	Belongs to the GPI family
BCV75_00970	COG0779	Required for maturation of 30S ribosomal subunits
BCV75_00975	COG0195	Participates in both transcription termination and antitermination
BCV75_00980	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BCV75_00985	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BCV75_00990	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BCV75_00995	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BCV75_01000	COG1185	polyribonucleotide nucleotidyltransferase activity
BCV75_01005	COG1733	regulation of RNA biosynthetic process
BCV75_01010	COG0702	epimerase
BCV75_01060	COG2086	electron transfer activity
BCV75_01090	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BCV75_01120	COG0477	Major facilitator Superfamily
BCV75_01135	COG0563	adenylate kinase activity
BCV75_01145	COG0671	phosphoesterase, PA-phosphatase related
BCV75_01155	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BCV75_01160	COG0628	permease
BCV75_01180	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BCV75_01185	COG1090	epimerase
BCV75_01190	COG0318	PFAM AMP-dependent synthetase and ligase
BCV75_01215	COG1049	propionate catabolic process, 2-methylcitrate cycle
BCV75_01240	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BCV75_01305	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BCV75_01315	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BCV75_01325	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
BCV75_01330	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
BCV75_01335	COG1034	ATP synthesis coupled electron transport
BCV75_01345	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BCV75_01355	COG0713	ATP synthesis coupled electron transport
BCV75_01370	COG1007	ATP synthesis coupled electron transport
BCV75_01375	COG1028	Short-chain dehydrogenase reductase Sdr
BCV75_01380	COG2851	Citrate transporter
BCV75_01395	COG0642	Histidine kinase
BCV75_01410	COG0675	Transposase, IS605 OrfB family
BCV75_01440	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BCV75_01445	COG4206	TonB-dependent receptor
BCV75_01450	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BCV75_01470	COG0277	FAD linked oxidase domain protein
BCV75_01475	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BCV75_01485	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BCV75_01490	COG2124	cytochrome p450
BCV75_01500	COG0305	Participates in initiation and elongation during chromosome replication
BCV75_01515	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BCV75_01520	COG0667	Aldo Keto reductase
BCV75_01525	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BCV75_01560	COG2194	sulfuric ester hydrolase activity
BCV75_01570	COG0352	thiamine-phosphate diphosphorylase activity
BCV75_01610	COG0745	RESPONSE REGULATOR receiver
BCV75_01615	COG2205	protein histidine kinase activity
BCV75_01635	COG0494	nUDIX hydrolase
BCV75_01645	COG2193	ferroxidase activity
BCV75_01660	COG3437	response regulator, receiver
BCV75_01660	COG2205	protein histidine kinase activity
BCV75_01660	COG4999	Histidine kinase
BCV75_01660	COG3850	Histidine kinase
BCV75_01695	COG0861	Integral membrane protein TerC family
BCV75_01700	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BCV75_01705	COG0531	amino acid
BCV75_01715	COG1116	anion transmembrane transporter activity
BCV75_01720	COG1322	Protein conserved in bacteria
BCV75_01730	COG2853	Lipoprotein
BCV75_01745	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BCV75_01750	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BCV75_01765	COG1074	ATP-dependent DNA helicase activity
BCV75_01790	COG0358	DNA primase activity
BCV75_01800	COG1610	YqeY-like protein
BCV75_01805	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BCV75_01810	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BCV75_01815	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BCV75_01820	COG0668	transmembrane transport
BCV75_01840	COG1183	phosphatidylcholine synthase activity
BCV75_01850	COG0442	prolyl-tRNA aminoacylation
BCV75_01870	COG0604	alcohol dehydrogenase
BCV75_01875	COG0330	HflC and HflK could
BCV75_01880	COG0330	HflC and HflK could
BCV75_01895	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BCV75_01900	COG0105	UTP biosynthetic process
BCV75_01905	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BCV75_01925	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BCV75_01930	COG1160	GTP binding
BCV75_01935	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BCV75_01940	COG4943	cyclic-guanylate-specific phosphodiesterase activity
BCV75_01945	COG1611	Belongs to the LOG family
BCV75_01950	COG4968	Prepilin-type N-terminal cleavage methylation domain
BCV75_01990	COG0675	Transposase, IS605 OrfB family
BCV75_02025	COG2878	Part of a membrane complex involved in electron transport
BCV75_02040	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BCV75_02045	COG3107	peptidoglycan biosynthetic process
BCV75_02055	COG1162	GTPase activity
BCV75_02060	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
BCV75_02070	COG0519	Catalyzes the synthesis of GMP from XMP
BCV75_02070	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BCV75_02100	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BCV75_02115	COG0037	tRNA processing
BCV75_02125	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BCV75_02135	COG3590	peptidase
BCV75_02155	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BCV75_02160	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BCV75_02180	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BCV75_02185	COG3178	'Phosphotransferase
BCV75_02190	COG1555	photosystem II stabilization
BCV75_02195	COG1477	protein flavinylation
BCV75_02220	COG4774	siderophore transport
BCV75_02240	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BCV75_02255	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
BCV75_02260	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BCV75_02265	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BCV75_02290	COG0459	protein refolding
BCV75_02300	COG1324	tolerance protein
BCV75_02310	COG0351	phosphomethylpyrimidine kinase
BCV75_02310	COG0352	thiamine-phosphate diphosphorylase activity
BCV75_02315	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BCV75_02360	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BCV75_02370	COG2311	Membrane
BCV75_02380	COG0791	NLP P60 protein
BCV75_02385	COG0791	NLP P60 protein
BCV75_02395	COG1301	dicarboxylic acid transport
BCV75_02405	COG0037	tRNA processing
BCV75_02410	COG1722	exodeoxyribonuclease VII activity
BCV75_02415	COG0142	geranyltranstransferase activity
BCV75_02440	COG1028	Short-chain dehydrogenase reductase Sdr
BCV75_02455	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BCV75_02460	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BCV75_02485	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BCV75_02490	COG0483	inositol monophosphate 1-phosphatase activity
BCV75_02500	COG1509	lysine 2,3-aminomutase activity
BCV75_02510	COG0402	S-adenosylhomocysteine deaminase activity
BCV75_02520	COG0546	phosphoglycolate phosphatase activity
BCV75_02530	COG5434	Belongs to the glycosyl hydrolase 28 family
BCV75_02535	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BCV75_02555	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BCV75_02560	COG1138	Cytochrome C-type biogenesis protein
BCV75_02565	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
BCV75_02580	COG4133	protoheme IX ABC transporter activity
BCV75_02585	COG0436	Aminotransferase
BCV75_02600	COG1187	pseudouridine synthase activity
BCV75_02605	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BCV75_02610	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BCV75_02630	COG1175	transmembrane transport
BCV75_02635	COG0395	ABC-type sugar transport system, permease component
BCV75_02665	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BCV75_02675	COG0776	regulation of translation
BCV75_02685	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
BCV75_02700	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BCV75_02705	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BCV75_02715	COG0519	Catalyzes the synthesis of GMP from XMP
BCV75_02715	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BCV75_02735	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BCV75_02740	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BCV75_02745	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BCV75_02750	COG0268	Binds directly to 16S ribosomal RNA
BCV75_02755	COG0728	peptidoglycan biosynthetic process
BCV75_02760	COG0196	riboflavin kinase activity
BCV75_02765	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BCV75_02880	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BCV75_02895	COG3409	Peptidoglycan-binding domain 1 protein
BCV75_02895	COG3757	hydrolase, family 25
BCV75_02905	COG1064	alcohol dehydrogenase
BCV75_02920	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BCV75_02925	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BCV75_02930	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BCV75_02930	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BCV75_02945	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BCV75_02950	COG0066	3-isopropylmalate dehydratase activity
BCV75_02955	COG0473	3-isopropylmalate dehydrogenase activity
BCV75_02985	COG0438	transferase activity, transferring glycosyl groups
BCV75_03005	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
BCV75_03010	COG0745	RESPONSE REGULATOR receiver
BCV75_03045	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BCV75_03055	COG2914	Belongs to the UPF0125 (RnfH) family
BCV75_03060	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BCV75_03070	COG0497	DNA recombination
BCV75_03075	COG1420	regulation of RNA biosynthetic process
BCV75_03080	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BCV75_03090	COG0484	heat shock protein binding
BCV75_03095	COG1605	Chorismate mutase
BCV75_03095	COG0287	Prephenate dehydrogenase
BCV75_03105	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BCV75_03130	COG4555	ABC transporter
BCV75_03135	COG1668	transmembrane transport
BCV75_03145	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BCV75_03150	COG1605	Chorismate mutase
BCV75_03150	COG0077	Prephenate dehydratase
BCV75_03155	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BCV75_03205	COG0322	excinuclease ABC activity
BCV75_03210	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BCV75_03235	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BCV75_03240	COG0489	protein tyrosine kinase activity
BCV75_03245	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
BCV75_03250	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BCV75_03300	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BCV75_03310	COG1192	Involved in chromosome partitioning
BCV75_03315	COG1475	DNA binding
BCV75_03325	COG0463	Glycosyl transferase, family 2
BCV75_03335	COG0318	PFAM AMP-dependent synthetase and ligase
BCV75_03345	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BCV75_03355	COG0676	glucose-6-phosphate 1-epimerase activity
BCV75_03365	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BCV75_03370	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BCV75_03385	COG1297	OPT oligopeptide transporter protein
BCV75_03395	COG1506	peptidase
BCV75_03395	COG0823	Involved in the tonB-independent uptake of proteins
BCV75_03400	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BCV75_03415	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BCV75_03430	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BCV75_03435	COG1381	Involved in DNA repair and RecF pathway recombination
BCV75_03440	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BCV75_03445	COG0571	ribonuclease III activity
BCV75_03465	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BCV75_03490	COG4953	penicillin-binding protein 1C
BCV75_03505	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
BCV75_03515	COG1686	Belongs to the peptidase S11 family
BCV75_03520	COG1678	Uncharacterized ACR, COG1678
BCV75_03530	COG0540	Belongs to the ATCase OTCase family
BCV75_03535	COG0460	homoserine dehydrogenase
BCV75_03535	COG0527	aspartate kinase activity
BCV75_03540	COG0083	homoserine kinase activity
BCV75_03550	COG0124	histidyl-tRNA synthetase
BCV75_03565	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BCV75_03575	COG0131	Imidazoleglycerol-phosphate dehydratase
BCV75_03575	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BCV75_03585	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BCV75_03600	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
BCV75_03605	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
BCV75_03610	COG0235	Class ii aldolase
BCV75_03615	COG0531	amino acid
BCV75_03620	COG0531	amino acid
BCV75_03625	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BCV75_03630	COG0277	FAD linked oxidase domain protein
BCV75_03635	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BCV75_03775	COG2951	lytic endotransglycosylase activity
BCV75_03795	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BCV75_03810	COG0495	leucyl-tRNA aminoacylation
BCV75_03820	COG3118	belongs to the thioredoxin family
BCV75_03825	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BCV75_03840	COG2183	response to ionizing radiation
BCV75_03845	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BCV75_03855	COG0328	RNA-DNA hybrid ribonuclease activity
BCV75_03860	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BCV75_03865	COG0631	protein serine/threonine phosphatase activity
BCV75_03880	COG0859	PFAM glycosyl transferase family 9
BCV75_03895	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BCV75_03900	COG2967	ApaG domain
BCV75_03905	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BCV75_03910	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BCV75_03915	COG0704	Plays a role in the regulation of phosphate uptake
BCV75_03920	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BCV75_03925	COG0581	inorganic phosphate transmembrane transporter activity
BCV75_03930	COG0573	inorganic phosphate transmembrane transporter activity
BCV75_03935	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BCV75_03940	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BCV75_03940	COG4651	solute:proton antiporter activity
BCV75_03955	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BCV75_03965	COG0488	(ABC) transporter
BCV75_04005	COG0358	DNA primase activity
BCV75_04095	COG0445	tRNA wobble uridine modification
BCV75_04120	COG1469	GTP cyclohydrolase I activity
BCV75_04125	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BCV75_04135	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BCV75_04145	COG2902	Dehydrogenase
BCV75_04150	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BCV75_04185	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BCV75_04190	COG4221	oxidoreductase activity
BCV75_04195	COG3077	Addiction module antitoxin, RelB DinJ family
BCV75_04200	COG3041	Addiction module toxin RelE StbE family
BCV75_04265	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BCV75_04285	COG2925	Exonuclease
BCV75_04300	COG0025	NhaP-type Na H and K H
BCV75_04310	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BCV75_04320	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BCV75_04345	COG0006	proline dipeptidase activity
BCV75_04385	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BCV75_04390	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
BCV75_04420	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BCV75_04425	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BCV75_04435	COG0557	exoribonuclease II activity
BCV75_04445	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BCV75_04450	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BCV75_04455	COG0302	gtp cyclohydrolase
BCV75_04465	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
BCV75_04470	COG1289	transmembrane transporter activity
BCV75_04480	COG0151	Belongs to the GarS family
BCV75_04485	COG0138	bifunctional purine biosynthesis protein purh
BCV75_04495	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BCV75_04505	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BCV75_04520	COG0596	Alpha beta hydrolase
BCV75_04530	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BCV75_04530	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BCV75_04555	COG0189	ligase activity
BCV75_04570	COG0840	transmembrane signaling receptor activity
BCV75_04605	COG0285	dihydrofolate synthase activity
BCV75_04630	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BCV75_04635	COG1301	dicarboxylic acid transport
BCV75_04640	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BCV75_04645	COG0357	Ribosomal RNA small subunit methyltransferase G
BCV75_04650	COG2091	lysine biosynthetic process via aminoadipic acid
BCV75_04715	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BCV75_04725	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BCV75_04765	COG0084	hydrolase, TatD family'
BCV75_04780	COG0552	protein localization to endoplasmic reticulum
BCV75_04790	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
BCV75_04795	COG0217	transcriptional regulatory protein
BCV75_04800	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
BCV75_04805	COG0632	four-way junction helicase activity
BCV75_04810	COG3158	transport of potassium into the cell
BCV75_04815	COG2255	four-way junction helicase activity
BCV75_04820	COG0824	Thioesterase
BCV75_04840	COG0823	Involved in the tonB-independent uptake of proteins
BCV75_04845	COG2885	chlorophyll binding
BCV75_04855	COG0602	queuosine metabolic process
BCV75_04860	COG0588	phosphoglycerate mutase activity
BCV75_04865	COG1515	deoxyribonuclease V activity
BCV75_04870	COG3104	oligopeptide transport
BCV75_04885	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BCV75_04895	COG0406	alpha-ribazole phosphatase activity
BCV75_05200	COG2337	Toxic component of a toxin-antitoxin (TA) module
BCV75_05220	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BCV75_05225	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BCV75_05255	COG0675	Transposase, IS605 OrfB family
BCV75_05345	COG3772	lysozyme
BCV75_05460	COG3617	BRO family, N-terminal domain
BCV75_05485	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BCV75_05490	COG3852	Histidine kinase
BCV75_05495	COG2204	response regulator
BCV75_05500	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BCV75_05505	COG0004	ammonium transporteR
BCV75_05510	COG0347	Belongs to the P(II) protein family
BCV75_05515	COG0174	glutamine synthetase
BCV75_05520	COG1968	undecaprenyl-diphosphatase activity
BCV75_05525	COG2353	YceI-like domain
BCV75_05545	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BCV75_05580	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BCV75_05585	COG1764	response to oxidative stress
BCV75_05590	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BCV75_05600	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BCV75_05620	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BCV75_05625	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BCV75_05630	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BCV75_05635	COG1399	metal-binding, possibly nucleic acid-binding protein
BCV75_05645	COG0714	Associated with various cellular activities
BCV75_05665	COG0537	adenosine 5'-monophosphoramidase activity
BCV75_05675	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BCV75_05700	COG0338	D12 class N6 adenine-specific DNA methyltransferase
BCV75_05720	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BCV75_05750	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BCV75_05785	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BCV75_05790	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BCV75_05795	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BCV75_05800	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BCV75_05815	COG0251	oxidation-reduction process
BCV75_05855	COG3657	addiction module killer protein
BCV75_05860	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BCV75_05955	COG2369	cell adhesion
BCV75_06000	COG3772	lysozyme
BCV75_06025	COG0305	Participates in initiation and elongation during chromosome replication
BCV75_06050	COG3617	BRO family, N-terminal domain
BCV75_06055	COG3617	BRO family, N-terminal domain
BCV75_06155	COG0629	single-stranded DNA binding
BCV75_06165	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BCV75_06170	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BCV75_06170	COG0392	lysyltransferase activity
BCV75_06185	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BCV75_06195	COG0463	Glycosyl transferase, family 2
BCV75_06240	COG3275	phosphorelay sensor kinase activity
BCV75_06250	COG2943	transferase activity, transferring hexosyl groups
BCV75_06265	COG2226	methyltransferase
BCV75_06280	COG2027	D-alanyl-D-alanine carboxypeptidase
BCV75_06290	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BCV75_06305	COG2900	Belongs to the SlyX family
BCV75_06320	COG0386	Belongs to the glutathione peroxidase family
BCV75_06330	COG1131	(ABC) transporter
BCV75_06350	COG3657	addiction module killer protein
BCV75_06355	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BCV75_06410	COG3657	addiction module killer protein
BCV75_06415	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BCV75_06510	COG2369	cell adhesion
BCV75_06530	COG5410	chromosome segregation
BCV75_06555	COG3772	lysozyme
BCV75_06605	COG0114	fumarate hydratase activity
BCV75_06615	COG2850	peptidyl-arginine hydroxylation
BCV75_06620	COG0567	Dehydrogenase, E1 component
BCV75_06645	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BCV75_06655	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BCV75_06660	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
BCV75_06665	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BCV75_06680	COG0254	rRNA binding
BCV75_06690	COG0583	DNA-binding transcription factor activity
BCV75_06695	COG3634	alkyl hydroperoxide reductase activity
BCV75_06700	COG0450	alkyl hydroperoxide reductase
BCV75_06710	COG1450	Type ii and iii secretion system protein
BCV75_06725	COG3166	PFAM Fimbrial assembly family protein
BCV75_06730	COG3156	type II secretion system protein K
BCV75_06735	COG4795	General secretion pathway protein
BCV75_06740	COG2165	general secretion pathway protein
BCV75_06745	COG4970	Tfp pilus assembly protein FimT
BCV75_06750	COG2165	general secretion pathway protein
BCV75_06755	COG1459	type II secretion system
BCV75_06760	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BCV75_06765	COG5295	Hep Hag repeat protein
BCV75_06780	COG2890	protein-(glutamine-N5) methyltransferase activity
BCV75_06785	COG0596	Alpha beta hydrolase
BCV75_06815	COG1561	YicC-like family, N-terminal region
BCV75_06820	COG0194	GDP metabolic process
BCV75_06825	COG1758	RNA polymerase activity
BCV75_06830	COG2895	sulfate adenylyltransferase (ATP) activity
BCV75_06830	COG0529	Catalyzes the synthesis of activated sulfate
BCV75_06835	COG0175	sulfate reduction
BCV75_06840	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BCV75_06850	COG0175	sulfate reduction
BCV75_06865	COG2912	Transglutaminase-like superfamily
BCV75_06885	COG0308	aminopeptidase N
BCV75_06890	COG2226	methyltransferase
BCV75_06900	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BCV75_06920	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BCV75_06935	COG1959	2 iron, 2 sulfur cluster binding
BCV75_06940	COG0719	Fe-S assembly protein
BCV75_06945	COG0396	ATPase activity
BCV75_06950	COG0719	Fe-S assembly protein
BCV75_06955	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BCV75_06970	COG0297	glycogen (starch) synthase activity
BCV75_06975	COG0726	polysaccharide deacetylase
BCV75_06980	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BCV75_06990	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BCV75_06995	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BCV75_07000	COG1609	Transcriptional regulator
BCV75_07015	COG0837	glucose binding
BCV75_07030	COG1028	Short-chain dehydrogenase reductase Sdr
BCV75_07035	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BCV75_07040	COG4191	Histidine kinase
BCV75_07045	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BCV75_07050	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BCV75_07055	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BCV75_07065	COG1674	ftsk spoiiie
BCV75_07070	COG0492	ferredoxin-NADP+ reductase activity
BCV75_07080	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
BCV75_07085	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BCV75_07090	COG0542	response to heat
BCV75_07095	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
BCV75_07110	COG2915	High frequency lysogenization protein hflD homolog
BCV75_07120	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BCV75_07135	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BCV75_07150	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BCV75_07155	COG4974	Belongs to the 'phage' integrase family
BCV75_07160	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BCV75_07205	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BCV75_07210	COG0271	Belongs to the BolA IbaG family
BCV75_07220	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
BCV75_07235	COG1137	ATPase activity
BCV75_07255	COG1660	Displays ATPase and GTPase activities
BCV75_07270	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BCV75_07290	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BCV75_07295	COG0629	single-stranded DNA binding
BCV75_07300	COG0142	geranyltranstransferase activity
BCV75_07305	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BCV75_07310	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BCV75_07315	COG1845	cytochrome c oxidase, subunit III
BCV75_07320	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BCV75_07325	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BCV75_07325	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BCV75_07345	COG0783	Belongs to the Dps family
BCV75_07350	COG0514	ATP-dependent DNA helicase (RecQ)
BCV75_07360	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BCV75_07370	COG0159	tryptophan synthase activity
BCV75_07375	COG0133	tryptophan synthase activity
BCV75_07380	COG0135	phosphoribosylanthranilate isomerase activity
BCV75_07395	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BCV75_07400	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BCV75_07405	COG2890	protein-(glutamine-N5) methyltransferase activity
BCV75_07425	COG0741	lytic transglycosylase activity
BCV75_07430	COG0617	tRNA 3'-terminal CCA addition
BCV75_07435	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BCV75_07450	COG0156	8-amino-7-oxononanoate synthase activity
BCV75_07455	COG2267	carboxylic ester hydrolase activity
BCV75_07465	COG1846	Transcriptional regulator
BCV75_07475	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BCV75_07485	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BCV75_07490	COG4208	sulfate ABC transporter
BCV75_07495	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
BCV75_07510	COG3142	Participates in the control of copper homeostasis
BCV75_07520	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BCV75_07525	COG0259	pyridoxamine-phosphate oxidase activity
BCV75_07535	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BCV75_07540	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BCV75_07545	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BCV75_07555	COG2353	YceI-like domain
BCV75_07570	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BCV75_07595	COG2894	cell division
BCV75_07615	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BCV75_07620	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BCV75_07630	COG0768	penicillin binding
BCV75_07635	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
BCV75_07645	COG1077	Cell shape determining protein MreB Mrl
BCV75_07675	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BCV75_07680	COG1127	ABC transporter
BCV75_07685	COG3218	ABC-type transport auxiliary lipoprotein component
BCV75_07685	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BCV75_07700	COG0644	oxidoreductase
BCV75_07700	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
BCV75_07710	COG2840	Smr protein MutS2
BCV75_07715	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BCV75_07720	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BCV75_07725	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
BCV75_07730	COG0148	phosphopyruvate hydratase activity
BCV75_07735	COG2877	3-deoxy-8-phosphooctulonate synthase activity
BCV75_07765	COG1253	flavin adenine dinucleotide binding
BCV75_07770	COG2733	membrane
BCV75_07795	COG0321	lipoyl(octanoyl) transferase activity
BCV75_07800	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BCV75_07835	COG0668	transmembrane transport
BCV75_07840	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
BCV75_07860	COG2373	Large extracellular alpha-helical protein
BCV75_07965	COG0582	viral genome integration into host DNA
BCV75_07980	COG0729	surface antigen
BCV75_07985	COG1956	GAF domain-containing protein
BCV75_07990	COG1643	Atp-dependent helicase
BCV75_08010	COG1131	(ABC) transporter
BCV75_08015	COG0842	Transport permease protein
BCV75_08050	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BCV75_08055	COG0039	L-malate dehydrogenase activity
BCV75_08060	COG0625	glutathione transferase activity
BCV75_08065	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BCV75_08090	COG1187	pseudouridine synthase activity
BCV75_08105	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BCV75_08110	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BCV75_08135	COG0776	regulation of translation
BCV75_08145	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BCV75_08155	COG0544	peptidyl-prolyl cis-trans isomerase activity
BCV75_08170	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BCV75_08185	COG0606	chelatase, subunit chli
BCV75_08190	COG2960	long-chain fatty acid transporting porin activity
BCV75_08195	COG0203	ribosomal protein L17
BCV75_08205	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BCV75_08210	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BCV75_08215	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BCV75_08220	COG0201	protein transport
BCV75_08225	COG0200	Binds to the 23S rRNA
BCV75_08230	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BCV75_08235	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BCV75_08240	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BCV75_08245	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BCV75_08250	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BCV75_08255	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BCV75_08260	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BCV75_08265	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BCV75_08270	COG0255	Belongs to the universal ribosomal protein uL29 family
BCV75_08280	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BCV75_08285	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BCV75_08290	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BCV75_08295	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BCV75_08300	COG0088	Forms part of the polypeptide exit tunnel
BCV75_08305	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BCV75_08315	COG0356	it plays a direct role in the translocation of protons across the membrane
BCV75_08325	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BCV75_08330	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BCV75_08335	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BCV75_08340	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BCV75_08345	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BCV75_08350	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BCV75_08360	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BCV75_08375	COG1064	alcohol dehydrogenase
BCV75_08390	COG0583	DNA-binding transcription factor activity
BCV75_08395	COG0312	modulator of DNA gyrase
BCV75_08400	COG3028	Belongs to the UPF0307 family
BCV75_08405	COG0312	modulator of DNA gyrase
BCV75_08415	COG1530	ribonuclease E activity
BCV75_08420	COG0424	maF-like protein
BCV75_08435	COG0494	nUDIX hydrolase
BCV75_08445	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BCV75_08455	COG0019	diaminopimelate decarboxylase activity
BCV75_08460	COG1024	Enoyl-CoA hydratase
BCV75_08475	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BCV75_08480	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BCV75_08485	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BCV75_08495	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BCV75_08505	COG0505	Belongs to the CarA family
BCV75_08510	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BCV75_08545	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BCV75_08565	COG1663	tetraacyldisaccharide 4'-kinase activity
BCV75_08570	COG1132	(ABC) transporter
BCV75_08580	COG0811	peptide transport
BCV75_08590	COG1136	(ABC) transporter
BCV75_08595	COG4591	ABC-type transport system involved in lipoprotein release permease component
BCV75_08610	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BCV75_08620	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
BCV75_08625	COG2009	succinate dehydrogenase
BCV75_08635	COG0354	folic acid binding
BCV75_08640	COG3842	ATPase activity
BCV75_08645	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BCV75_08650	COG0837	glucose binding
BCV75_08655	COG0363	glucosamine-6-phosphate deaminase activity
BCV75_08720	COG0233	cytoplasmic translational termination
BCV75_08725	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BCV75_08730	COG0575	Belongs to the CDS family
BCV75_08750	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BCV75_08755	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BCV75_08760	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BCV75_08765	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BCV75_08770	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BCV75_08780	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
BCV75_08795	COG2937	Belongs to the GPAT DAPAT family
BCV75_08820	COG1946	Acyl-CoA thioesterase
BCV75_08830	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
BCV75_08835	COG1914	H( )-stimulated, divalent metal cation uptake system
BCV75_08840	COG1321	iron dependent repressor
BCV75_08845	COG0590	tRNA wobble adenosine to inosine editing
BCV75_08885	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BCV75_08890	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BCV75_08895	COG0165	Argininosuccinate lyase
BCV75_08905	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BCV75_08915	COG0137	argininosuccinate synthase activity
BCV75_08920	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BCV75_08930	COG0215	cysteine-tRNA ligase activity
BCV75_08935	COG2166	iron-sulfur cluster assembly
BCV75_08950	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BCV75_08955	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BCV75_08960	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BCV75_08970	COG3706	GGDEF domain
BCV75_08980	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BCV75_08990	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BCV75_08995	COG0742	ribosomal rna small subunit methyltransferase
BCV75_09000	COG0326	Molecular chaperone. Has ATPase activity
BCV75_09005	COG0281	malic enzyme
BCV75_09005	COG0280	phosphate acetyltransferase
BCV75_09010	COG1301	dicarboxylic acid transport
BCV75_09025	COG0784	Response regulator, receiver
BCV75_09025	COG2205	protein histidine kinase activity
BCV75_09060	COG0556	nucleotide-excision repair
BCV75_09085	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BCV75_09105	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BCV75_09110	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BCV75_09130	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BCV75_09130	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BCV75_09150	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BCV75_09155	COG0488	(ABC) transporter
BCV75_09165	COG3011	Protein conserved in bacteria
BCV75_09175	COG0564	pseudouridine synthase activity
BCV75_09180	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BCV75_09190	COG1918	ferrous iron import across plasma membrane
BCV75_09190	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BCV75_09210	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BCV75_09220	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BCV75_09235	COG0758	DNA mediated transformation
BCV75_09240	COG2922	Belongs to the Smg family
BCV75_09250	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BCV75_09250	COG1754	DNA topoisomerase type I activity
BCV75_09255	COG0009	L-threonylcarbamoyladenylate synthase
BCV75_09285	COG2969	positive regulation of protein catabolic process
BCV75_09290	COG0625	glutathione transferase activity
BCV75_09295	COG2857	Cytochrome c1
BCV75_09300	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BCV75_09320	COG1702	phosphate starvation-inducible protein PhoH
BCV75_09325	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BCV75_09335	COG4535	Mg2 and Co2 transporter CorC
BCV75_09475	COG1199	ATP-dependent helicase activity
BCV75_09485	COG0288	reversible hydration of carbon dioxide
BCV75_09500	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BCV75_09520	COG0508	dehydrogenase complex catalyzes the overall conversion of
BCV75_09525	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BCV75_09540	COG0626	cystathionine gamma-synthase activity
BCV75_09545	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BCV75_09550	COG0739	heme binding
BCV75_09555	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
BCV75_09560	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BCV75_09565	COG1238	metal cluster binding
BCV75_09580	COG5002	protein histidine kinase activity
BCV75_09585	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BCV75_09590	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BCV75_09595	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BCV75_09600	COG3858	chitin binding
BCV75_09600	COG1388	LysM domain
BCV75_09605	COG3525	Glycosyl hydrolase, family 20, catalytic domain
BCV75_09615	COG1472	Belongs to the glycosyl hydrolase 3 family
BCV75_09630	COG3537	Alpha-1,2-mannosidase
BCV75_09640	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BCV75_09645	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BCV75_09650	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
BCV75_09655	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BCV75_09660	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BCV75_09700	COG3588	fructose-bisphosphate aldolase
BCV75_09705	COG0469	pyruvate kinase activity
BCV75_09710	COG0126	phosphoglycerate kinase activity
BCV75_09715	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BCV75_09720	COG0735	belongs to the Fur family
BCV75_09730	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
BCV75_09730	COG5297	Belongs to the glycosyl hydrolase family 6
BCV75_09735	COG0612	Peptidase, M16
BCV75_09750	COG4305	rare lipoprotein A
BCV75_09755	COG0653	protein targeting
BCV75_09760	COG0739	heme binding
BCV75_09770	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
BCV75_09775	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BCV75_09785	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BCV75_09790	COG1181	Belongs to the D-alanine--D-alanine ligase family
BCV75_09795	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BCV75_09800	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BCV75_09815	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BCV75_09820	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BCV75_09830	COG3116	cell division
BCV75_09835	COG0275	rRNA processing
BCV75_09850	COG3273	potassium ion transport
BCV75_09850	COG0471	metal ion transport
BCV75_09855	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BCV75_09890	COG2755	lipolytic protein G-D-S-L family
BCV75_09890	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BCV75_09920	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BCV75_09950	COG0640	Transcriptional regulator
BCV75_09955	COG2391	methyltransferase activity
BCV75_09960	COG2391	methyltransferase activity
BCV75_09965	COG0730	response to heat
BCV75_09970	COG0717	Belongs to the dCTP deaminase family
BCV75_09980	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BCV75_09985	COG0860	N-Acetylmuramoyl-L-alanine amidase
BCV75_09990	COG0802	atpase or kinase
BCV75_10030	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
BCV75_10045	COG0776	regulation of translation
BCV75_10050	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BCV75_10050	COG0072	phenylalanine-tRNA ligase activity
BCV75_10055	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BCV75_10060	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BCV75_10070	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BCV75_10075	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BCV75_10100	COG0745	RESPONSE REGULATOR receiver
BCV75_10110	COG0237	dephospho-CoA kinase activity
BCV75_10115	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BCV75_10160	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BCV75_10170	COG2831	hemolysin activation secretion protein
BCV75_10195	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
BCV75_10215	COG3115	cell septum assembly
BCV75_10225	COG0359	binds to the 23S rRNA
BCV75_10230	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BCV75_10240	COG0316	Belongs to the HesB IscA family
BCV75_10245	COG0017	Asparaginyl-tRNA synthetase
BCV75_10270	COG0167	dihydroorotate dehydrogenase activity
BCV75_10275	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BCV75_10280	COG0697	spore germination
BCV75_10290	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BCV75_10300	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
BCV75_10305	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BCV75_10320	COG1132	(ABC) transporter
BCV75_10325	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BCV75_10330	COG1538	Outer membrane efflux protein
BCV75_10335	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BCV75_10345	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BCV75_10370	COG0473	3-isopropylmalate dehydrogenase activity
BCV75_10380	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BCV75_10390	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
BCV75_10400	COG0316	Belongs to the HesB IscA family
BCV75_10400	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BCV75_10405	COG2154	pterin-4-alpha-carbinolamine dehydratase
BCV75_10415	COG0564	pseudouridine synthase activity
BCV75_10425	COG2197	response regulator
BCV75_10465	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
BCV75_10470	COG1278	Cold shock
BCV75_10480	COG0501	Belongs to the peptidase M48B family
BCV75_10485	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BCV75_10490	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BCV75_10495	COG0049	tRNA binding
BCV75_10500	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BCV75_10505	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BCV75_10510	COG0085	RNA polymerase activity
BCV75_10515	COG0222	ribosome binding
BCV75_10520	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BCV75_10525	COG0081	regulation of translation
BCV75_10530	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BCV75_10535	COG0250	Participates in transcription elongation, termination and antitermination
BCV75_10540	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BCV75_10550	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BCV75_10570	COG0012	GTP binding
BCV75_10575	COG0193	aminoacyl-tRNA hydrolase activity
BCV75_10595	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BCV75_10600	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
BCV75_10610	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BCV75_10615	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BCV75_10620	COG0116	Belongs to the methyltransferase superfamily
BCV75_10620	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BCV75_10655	COG2095	MarC family integral membrane protein
BCV75_10660	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BCV75_10675	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BCV75_10685	COG2132	Multicopper oxidase
BCV75_10695	COG0210	DNA helicase
BCV75_10700	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
BCV75_10705	COG0616	signal peptide processing
BCV75_10710	COG0534	Mate efflux family protein
BCV75_10730	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BCV75_10740	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BCV75_10745	COG2201	protein-glutamate methylesterase activity
BCV75_10750	COG2177	Part of the ABC transporter FtsEX involved in
BCV75_10755	COG2884	Cell division ATP-binding protein ftsE
BCV75_10760	COG0513	Belongs to the DEAD box helicase family
BCV75_10765	COG3118	belongs to the thioredoxin family
BCV75_10770	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BCV75_10785	COG0793	Belongs to the peptidase S41A family
BCV75_10790	COG4942	peptidase
BCV75_10800	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
BCV75_10805	COG0493	'glutamate synthase
BCV75_10810	COG0069	glutamate synthase activity
BCV75_10810	COG0070	glutamate synthase
BCV75_10810	COG0067	glutamate synthase
BCV75_10840	COG1028	Short-chain dehydrogenase reductase Sdr
BCV75_10865	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BCV75_10890	COG0732	type I restriction modification DNA specificity domain
BCV75_10910	COG1280	lysine exporter protein (LysE YggA)
BCV75_10920	COG4942	peptidase
BCV75_10950	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BCV75_10965	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
BCV75_11045	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BCV75_11050	COG3657	addiction module killer protein
BCV75_11175	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BCV75_11185	COG0706	membrane insertase activity
BCV75_11190	COG0594	ribonuclease P activity
BCV75_11220	COG4644	lycopene metabolic process
BCV75_11235	COG3657	addiction module killer protein
BCV75_11240	COG3609	addiction module antidote protein, CC2985 family
BCV75_11250	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BCV75_11345	COG0629	single-stranded DNA binding
BCV75_11355	COG4962	Type ii secretion system protein e
BCV75_11370	COG3451	type IV secretory pathway VirB4