locus-tag	class	description
BC375_00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
BC375_00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
BC375_00015	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
BC375_00025	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
BC375_00035	ENOG4108K0D	peptidase, M48
BC375_00075	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
BC375_00095	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
BC375_00110	ENOG4108ZUW	Major pilin subunit
BC375_00140	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
BC375_00145	ENOG4105CGF	Aromatic amino acid aminotransferase
BC375_00165	ENOG4105D6S	protein involved in catabolism of external DNA
BC375_00175	ENOG4108JA2	transcriptioN-repair coupling factor
BC375_00185	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
BC375_00190	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
BC375_00195	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
BC375_00210	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
BC375_00225	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
BC375_00235	ENOG4105MJ2	Competence protein
BC375_00240	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
BC375_00245	ENOG4105D78	K07001 NTE family protein
BC375_00250	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
BC375_00285	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
BC375_00295	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BC375_00330	ENOG4108VEV	chaperone
BC375_00335	ENOG4105X0I	Fimbrial
BC375_00340	ENOG4107TH8	cina domain protein
BC375_00345	ENOG4105CSH	Transporter
BC375_00350	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
BC375_00355	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
BC375_00360	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
BC375_00365	ENOG4105EEI	dihydropteroate synthase
BC375_00375	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
BC375_00380	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
BC375_00385	ENOG4105HBR	Rna-binding protein
BC375_00415	ENOG4105D1S	lipid A biosynthesis
BC375_00420	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
BC375_00430	ENOG4105K5M	30s ribosomal protein S16
BC375_00435	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
BC375_00440	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
BC375_00445	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
BC375_00450	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
BC375_00455	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
BC375_00460	ENOG4105KUZ	arsenate reductase
BC375_00465	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
BC375_00470	ENOG4105CAQ	asparagine synthetase
BC375_00480	ENOG4105EA8	2-Nitropropane dioxygenase
BC375_00490	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
BC375_00495	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
BC375_00510	ENOG4105DGW	oligopeptidase A
BC375_00535	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
BC375_00575	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
BC375_00585	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
BC375_00595	ENOG4105EMU	Dehydrogenase
BC375_00615	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
BC375_00625	ENOG4107QKV	phosphomannomutase
BC375_00635	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
BC375_00665	ENOG4105EYM	Major Facilitator superfamily
BC375_00670	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
BC375_00675	ENOG4105DR5	peptidase
BC375_00680	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
BC375_00710	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
BC375_00725	ENOG4105C2D	reductase
BC375_00730	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
BC375_00735	ENOG4108UT2	hemolysin iii
BC375_00745	ENOG4105EYA	deoxyribonuclease
BC375_00760	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
BC375_00765	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
BC375_00780	ENOG4105DXN	mazG family
BC375_00785	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
BC375_00790	ENOG4107RK2	ADP-ribose diphosphatase NudE
BC375_00800	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
BC375_00810	ENOG4105C1J	atp-dependent rna helicase
BC375_00815	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
BC375_00840	ENOG4108YXA	Membrane
BC375_00845	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
BC375_00850	ENOG4105C0B	DNA polymerase III (alpha subunit)
BC375_00870	ENOG4105CRQ	synthase (Component I)
BC375_00875	ENOG4105DDQ	anthranilate synthase
BC375_00880	ENOG4107QYG	anthranilate phosphoribosyltransferase
BC375_00885	ENOG4105DK0	Indole-3-glycerol phosphate synthase
BC375_00905	ENOG4105DC7	peptidase M24
BC375_00920	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
BC375_00925	ENOG4105VIE	preprotein translocase, subunit YajC
BC375_00930	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
BC375_00945	ENOG4105DJ0	Poly(A) Polymerase
BC375_00950	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BC375_00955	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
BC375_00960	ENOG4107R03	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
BC375_00965	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
BC375_00970	ENOG4107QP8	phosphohexose isomerase
BC375_00985	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
BC375_00990	ENOG4105CHV	Transcription elongation factor NusA
BC375_00995	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
BC375_01000	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
BC375_01010	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
BC375_01015	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
BC375_01025	ENOG4105ECR	NmrA family
BC375_01070	ENOG4105C10	Electron transfer flavoprotein
BC375_01075	ENOG4105BZJ	Electron transfer flavoprotein
BC375_01090	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
BC375_01105	ENOG4107QKV	phosphomannomutase
BC375_01135	ENOG4105CBP	Major Facilitator
BC375_01150	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
BC375_01155	ENOG4105DFU	Cell wall formation (By similarity)
BC375_01160	ENOG410841Q	phosphoesterase PA-phosphatase related protein
BC375_01170	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
BC375_01175	ENOG4105C02	permease
BC375_01195	ENOG4105C0H	protease
BC375_01200	ENOG4105ECP	epimerase
BC375_01205	ENOG4105CEY	Amp-dependent synthetase and ligase
BC375_01215	ENOG4107QM5	aconitate hydratase
BC375_01225	ENOG4107QIJ	Aconitate hydratase 2
BC375_01250	ENOG4105DZR	Type I site-specific deoxyribonuclease
BC375_01315	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
BC375_01325	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
BC375_01335	ENOG4105GKE	subunit e
BC375_01345	ENOG4108IEH	NADH dehydrogenase subunit g
BC375_01355	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
BC375_01360	ENOG4105DF2	NADH dehydrogenase subunit j
BC375_01365	ENOG41080FQ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
BC375_01370	ENOG4105D65	subunit l
BC375_01375	ENOG4105C8S	subunit m
BC375_01380	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
BC375_01385	ENOG4105CHR	reductase
BC375_01390	ENOG4105D4T	Citrate transporter
BC375_01405	ENOG4105DHQ	Histidine kinase
BC375_01420	ENOG4105D7V	transposase
BC375_01450	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
BC375_01455	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
BC375_01460	ENOG41080I0	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
BC375_01470	ENOG4105CDV	Ompa motb domain protein
BC375_01480	ENOG4105CQB	FAD linked oxidase domain protein
BC375_01485	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
BC375_01490	ENOG4105KME	endoribonuclease L-psp
BC375_01500	ENOG4106A3M	Cytochrome p-450
BC375_01510	ENOG4105CDU	Replicative dna helicase
BC375_01520	ENOG4105CDV	Ompa motb domain protein
BC375_01525	ENOG4108RVA	ribokinase
BC375_01530	ENOG4105CPC	Aldo Keto reductase
BC375_01535	ENOG4108JQC	penicillin-binding protein 1A
BC375_01560	ENOG4105E4G	Type IV pilus
BC375_01570	ENOG4105DIJ	Phosphoethanolamine transferase
BC375_01580	ENOG4107S5G	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
BC375_01590	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
BC375_01605	ENOG4105UGU	tonB-dependent Receptor
BC375_01620	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
BC375_01625	ENOG4105IFJ	Histidine kinase
BC375_01630	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
BC375_01645	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
BC375_01655	ENOG4108UQY	Iron-storage protein
BC375_01665	ENOG4105BZU	Histidine kinase
BC375_01700	ENOG4105DU1	integral membrane protein, terc
BC375_01705	ENOG4105DR4	Methyltransferase
BC375_01710	ENOG4105CUB	amino acid
BC375_01730	ENOG4107QSV	RmuC domain protein
BC375_01755	ENOG4107PE3	Mammalian cell entry related domain protein
BC375_01760	ENOG4105CY3	ABC transporter, permease
BC375_01765	ENOG4105DHJ	ABC, transporter
BC375_01795	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
BC375_01805	ENOG4105KTH	gatB Yqey
BC375_01810	ENOG4105VCC	30S ribosomal protein S21
BC375_01815	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
BC375_01820	ENOG4107ZVW	dihydroneopterin aldolase
BC375_01825	ENOG4105CUY	Mechanosensitive ion channel
BC375_01830	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
BC375_01845	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
BC375_01855	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
BC375_01870	ENOG4105M3Z	response regulator
BC375_01880	ENOG4107QJR	hflk protein
BC375_01885	ENOG4105EPW	hflc protein
BC375_01895	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
BC375_01900	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
BC375_01905	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
BC375_01910	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
BC375_01930	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
BC375_01935	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
BC375_01940	ENOG4105D06	uba thif-type nad fad binding protein
BC375_01950	ENOG41066DG	(EAL) domain protein
BC375_01955	ENOG4105EWT	decarboxylase family
BC375_01960	ENOG4106855	Competence protein
BC375_02000	ENOG4105D7V	transposase
BC375_02040	ENOG4108R3D	Electron transport complex
BC375_02045	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
BC375_02055	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
BC375_02060	ENOG4105E1C	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity)
BC375_02070	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
BC375_02075	ENOG41090JD	Blue (Type 1) copper domain protein
BC375_02090	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
BC375_02120	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
BC375_02135	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
BC375_02145	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
BC375_02160	ENOG4105C9K	Endothelin-converting enzyme 1
BC375_02180	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
BC375_02185	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
BC375_02195	ENOG4105C02	permease
BC375_02205	ENOG4108S0S	Nucleotidyl transferase
BC375_02210	ENOG4105EHM	Aminoglycoside phosphotransferase
BC375_02215	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
BC375_02220	ENOG4105CJ2	(LipO)protein
BC375_02240	ENOG4107E2E	PKHD-type hydroxylase
BC375_02245	ENOG4108IU3	tonb-dependent siderophore receptor
BC375_02265	ENOG4105C6T	cysteine synthase
BC375_02280	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
BC375_02285	ENOG4107TXM	Nad-dependent epimerase dehydratase
BC375_02290	ENOG4108IAJ	Nad-dependent epimerase dehydratase
BC375_02315	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
BC375_02325	ENOG4105VF7	tolerance protein
BC375_02330	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
BC375_02335	ENOG4105DWF	phosphomethylpyrimidine kinase
BC375_02340	ENOG4105E2X	shikimate dehydrogenase
BC375_02370	ENOG4108V1T	peptidylprolyl cis-trans isomerase
BC375_02380	ENOG4105CSM	endonuclease III
BC375_02395	ENOG4108YZY	peptidylprolyl cis-trans isomerase
BC375_02400	ENOG4105K4H	Nlp p60 protein
BC375_02405	ENOG4105K4H	Nlp p60 protein
BC375_02425	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
BC375_02430	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
BC375_02435	ENOG4105CTB	Polyprenyl synthetase
BC375_02445	ENOG4105DDI	hemolysin-type calcium-binding region
BC375_02450	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
BC375_02455	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
BC375_02460	ENOG4105CHR	reductase
BC375_02470	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
BC375_02480	ENOG4105HHA	aminodeoxychorismate lyase
BC375_02485	ENOG4107QRG	dna polymerase iii
BC375_02505	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
BC375_02510	ENOG4105ECY	inositol monophosphatase
BC375_02520	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
BC375_02530	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
BC375_02540	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
BC375_02555	ENOG4105DWV	Homoserine O-trans-acetylase
BC375_02570	ENOG4105KWW	Biogenesis protein
BC375_02575	ENOG4107QX9	Thiol disulfide interChange protein
BC375_02580	ENOG4105DA4	cytochrome c-type biogenesis protein
BC375_02585	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
BC375_02590	ENOG41060IM	Heme exporter protein
BC375_02595	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
BC375_02600	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
BC375_02605	ENOG4105CHM	Aminotransferase
BC375_02620	ENOG4105FE9	pseudouridine synthase
BC375_02625	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
BC375_02630	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
BC375_02650	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
BC375_02655	ENOG4105DRS	transport system, permease
BC375_02675	ENOG4105DWY	Agmatine deiminase
BC375_02685	ENOG4105CAT	Cytidine monophosphate kinase
BC375_02690	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
BC375_02695	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
BC375_02705	ENOG4105CFV	Tetratricopeptide repeat protein
BC375_02720	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
BC375_02725	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
BC375_02730	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
BC375_02735	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
BC375_02755	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
BC375_02760	ENOG4105K46	50S ribosomal protein l27
BC375_02765	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BC375_02770	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
BC375_02775	ENOG4105CJR	Integral membrane protein (MviN
BC375_02780	ENOG4105DTN	riboflavin biosynthesis protein ribF
BC375_02785	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
BC375_02880	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
BC375_02885	ENOG4108JJA	ABC, transporter
BC375_02920	ENOG4107YXZ	hydrolase, family 25
BC375_02930	ENOG4105DQ4	alcohol dehydrogenase
BC375_02945	ENOG4105BZS	acriflavin resistance protein
BC375_02950	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
BC375_02955	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
BC375_02970	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
BC375_02975	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
BC375_02980	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
BC375_02995	ENOG4105D3Q	Sugar transferase
BC375_03010	ENOG4107UFF	group 1 glycosyl transferase
BC375_03025	ENOG4108NQK	Catalyzes the transfer of a glucuronic acid (GlcA) residue from UDP-glucuronate to mannose-alpha-1,3-glucose-beta- 1,4-glucose-P-P-polyisoprenyl to form the lipid-linked tetrasaccharide GlcA-Man-Glc(2)-PP-Pol, with a glucuronic acid- beta-mannose linkage. Is involved in the biosynthesis of the exopolysaccharide xanthan, since it catalyzes the fourth glycosylation step in the assembly of the pentasaccharide-P-P- polyisoprenyl repeating unit of xanthan. Is unable to use the trisaccharide acceptor freed from the pyrophosphate lipid moiety. Does not show specificity for the lipidic portion of the acceptor. Shows diminished activity when tested with 6-O-acetyl-mannose- alpha-1,3-glucose-beta-1,4-glucose-P-P-polyisoprenyl, a
BC375_03030	ENOG4108UHC	Glycosyl transferase, wecb taga cpsf family
BC375_03035	ENOG4105EFQ	Two component transcriptional regulator (Winged helix family
BC375_03045	ENOG41080ZE	Adenylate cyclase
BC375_03055	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
BC375_03070	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
BC375_03085	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
BC375_03090	ENOG41090R7	Ferric uptake
BC375_03095	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
BC375_03100	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
BC375_03105	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BC375_03110	ENOG4105CFG	Acts as a chaperone (By similarity)
BC375_03115	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
BC375_03125	ENOG4105ETX	regulatoR
BC375_03130	ENOG41080IJ	Diacylglycerol kinase
BC375_03155	ENOG4108IUW	ABC transporter
BC375_03160	ENOG4108SDH	ABC, transporter
BC375_03170	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
BC375_03180	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
BC375_03230	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
BC375_03235	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
BC375_03255	ENOG4105D52	delta-aminolevulinic acid dehydratase
BC375_03265	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
BC375_03270	ENOG4105D1F	ATP-binding protein
BC375_03275	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
BC375_03330	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
BC375_03340	ENOG4107QJE	Chromosome Partitioning Protein
BC375_03345	ENOG4105FA0	parb-like partition protein
BC375_03365	ENOG410680H	amp-dependent synthetase and ligase
BC375_03375	ENOG4105WPN	DNA integration recombination invertion protein
BC375_03385	ENOG4105DSB	aldose 1-epimerase
BC375_03395	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
BC375_03400	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
BC375_03405	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
BC375_03415	ENOG4105EPD	Oligopeptide transporter, Opt family
BC375_03425	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
BC375_03430	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
BC375_03445	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
BC375_03455	ENOG4107QN1	sodium solute
BC375_03460	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
BC375_03465	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
BC375_03470	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
BC375_03475	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
BC375_03485	ENOG4105C3F	Signal peptidase i
BC375_03495	ENOG4105C0H	protease
BC375_03505	ENOG4105EMN	RNA polymerase sigma factor
BC375_03520	ENOG4108JQB	penicillin-binding protein 1C
BC375_03535	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
BC375_03545	ENOG4105DZ1	carboxypeptidase
BC375_03550	ENOG4108UJU	UPF0301 protein
BC375_03560	ENOG4105CXT	aspartate transcarbamylase
BC375_03565	ENOG4105CFH	Aspartokinase
BC375_03570	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
BC375_03580	ENOG4105CUT	histidyl-tRNA synthetase
BC375_03590	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
BC375_03595	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
BC375_03605	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
BC375_03615	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
BC375_03630	ENOG4106YVY	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) (By similarity)
BC375_03635	ENOG4108CAF	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity)
BC375_03640	ENOG4107QY0	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity)
BC375_03645	ENOG4105CUB	amino acid
BC375_03650	ENOG4105CUB	amino acid
BC375_03655	ENOG4108JQ1	Dehydrogenase
BC375_03660	ENOG4105CQB	FAD linked oxidase domain protein
BC375_03665	ENOG4105FUQ	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
BC375_03805	ENOG4105K6T	rare lipoprotein A
BC375_03810	ENOG4105CVE	Lytic murein transglycosylase
BC375_03830	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
BC375_03845	ENOG4105C8T	Leucyl-tRNA synthetase
BC375_03855	ENOG4105K63	Thioredoxin
BC375_03860	ENOG4105F0N	pyrophosphate phospho-hydrolase
BC375_03875	ENOG4105BZM	domain protein
BC375_03885	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
BC375_03895	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
BC375_03900	ENOG4107RZZ	dna polymerase iii epsilon subunit
BC375_03905	ENOG4108ZF3	Phosphatase
BC375_03920	ENOG4105DKP	glycosyl transferase, family 9
BC375_03925	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
BC375_03935	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
BC375_03940	ENOG4105NWN	ApaG protein
BC375_03945	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
BC375_03950	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
BC375_03955	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
BC375_03960	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
BC375_03965	ENOG4105E2Z	phosphate ABC transporter (Permease
BC375_03970	ENOG4105C8U	phosphate abc transporter
BC375_03975	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
BC375_03980	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
BC375_03990	ENOG4107RNH	Outer membrane receptor FepA
BC375_03995	ENOG4107ZXU	DSBA oxidoreductase
BC375_04000	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
BC375_04005	ENOG4105C5H	ABC transporter
BC375_04040	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
BC375_04140	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
BC375_04160	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
BC375_04165	ENOG4108Z0R	Transferase
BC375_04170	ENOG4105BZS	acriflavin resistance protein
BC375_04175	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
BC375_04185	ENOG4105C7I	Dehydrogenase
BC375_04190	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
BC375_04225	ENOG4105BZS	acriflavin resistance protein
BC375_04230	ENOG4105EMU	Dehydrogenase
BC375_04260	ENOG4105C26	Dehydrogenase
BC375_04310	ENOG4108C33	Resolvase
BC375_04330	ENOG4105CJB	Exodeoxyribonuclease I
BC375_04345	ENOG4105EEQ	Na H antiporter
BC375_04355	ENOG4105E66	phosphoriboisomerase A
BC375_04365	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
BC375_04375	ENOG4105W8B	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
BC375_04390	ENOG4107RAQ	aminopeptidase
BC375_04430	ENOG4105CM2	brancheD-chain amino acid aminotransferase
BC375_04435	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
BC375_04455	ENOG4106WTF	Glycosyl transferase, family 2
BC375_04465	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
BC375_04470	ENOG4107ZT5	Thiol disulfide interchange protein
BC375_04480	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
BC375_04490	ENOG4105C2N	RNA methyltransferase TrmH family group 3
BC375_04495	ENOG4108Z0R	Transferase
BC375_04500	ENOG4105EUJ	GTP cyclohydrolase i
BC375_04510	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
BC375_04515	ENOG4105EM2	membrane
BC375_04525	ENOG4105C12	Phosphoribosylglycinamide synthetase
BC375_04530	ENOG4105DC1	bifunctional purine biosynthesis protein purh
BC375_04540	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
BC375_04550	ENOG4105E2T	synthase III
BC375_04565	ENOG4108J2P	Alpha beta hydrolase fold
BC375_04570	ENOG4105PI0	Ferredoxin
BC375_04575	ENOG4105C4K	Nad synthetase
BC375_04600	ENOG4105D7Z	glutathione synthase
BC375_04605	ENOG4108UNF	response regulator
BC375_04610	ENOG4108ZGA	chew protein
BC375_04615	ENOG4105C8Q	Methyl-accepting chemotaxis
BC375_04620	ENOG4105CBS	Chea signal transduction histidine kinase
BC375_04635	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
BC375_04650	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
BC375_04660	ENOG4105DGW	oligopeptidase A
BC375_04680	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
BC375_04685	ENOG4105CK2	sodium dicarboxylate symporter
BC375_04690	ENOG4105CV1	Transketolase (EC 2.2.1.1)
BC375_04695	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
BC375_04760	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
BC375_04770	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
BC375_04780	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
BC375_04820	ENOG4105F8V	Hydrolase, tatD family
BC375_04835	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
BC375_04840	ENOG4105CEN	a g-specific adenine glycosylase
BC375_04845	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
BC375_04850	ENOG4105CDY	transcriptional regulatory protein
BC375_04855	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
BC375_04860	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
BC375_04865	ENOG4105DFH	Transport of potassium into the cell (By similarity)
BC375_04870	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
BC375_04875	ENOG4107YD3	Thioesterase
BC375_04880	ENOG4105E02	MotA TolQ exbB proton channel
BC375_04885	ENOG4105M8F	Biopolymer transport protein exbD tolR
BC375_04895	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
BC375_04900	ENOG4105KCK	Peptidoglycan-associated lipoprotein
BC375_04910	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
BC375_04915	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
BC375_04920	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
BC375_04925	ENOG4105DUX	Transporter
BC375_04935	ENOG4105DP0	ferredoxin-NADP reductase
BC375_04940	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
BC375_04950	ENOG4105CVJ	phosphoglycerate mutase
BC375_05265	ENOG4105NFY	transcriptional modulator of maze toxin, mazf
BC375_05285	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
BC375_05290	ENOG4105C9M	aspartyl-trna synthetase
BC375_05295	ENOG4107GFK	fumarate
BC375_05315	ENOG4105D7V	transposase
BC375_05405	ENOG4105KUS	lysozyme
BC375_05520	ENOG4105WXW	Antirepressor
BC375_05545	ENOG4108J6E	Pfam:Phage_integr_N
BC375_05550	ENOG4105CUX	Signal transduction histidine kinase
BC375_05555	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
BC375_05560	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
BC375_05565	ENOG4105BZU	Histidine kinase
BC375_05575	ENOG4105C5F	glutamine synthetase
BC375_05580	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
BC375_05585	ENOG4108YYC	ycei family
BC375_05605	ENOG4105RKW	reductase (By
BC375_05640	ENOG4105D6Z	AFG1 family ATPase
BC375_05645	ENOG4108ZHJ	Organic hydroperoxide resistance protein
BC375_05655	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
BC375_05660	ENOG4105CN1	protease
BC375_05665	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
BC375_05680	ENOG4105C7B	Threonine dehydratase
BC375_05685	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
BC375_05690	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
BC375_05695	ENOG4105VGS	50s ribosomal protein l32
BC375_05700	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
BC375_05710	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
BC375_05720	ENOG4105F8C	transglutaminase domain-containing protein
BC375_05730	ENOG4105K59	histidine triad (HIT) protein
BC375_05740	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
BC375_05745	ENOG4107QMP	dna polymerase iii subunits gamma and tau
BC375_05765	ENOG4107R5S	dna adenine
BC375_05785	ENOG4107YZP	Rhodanese domain protein
BC375_05810	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
BC375_05815	ENOG4108194	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
BC375_05835	ENOG4105X0D	Fimbrial protein
BC375_05850	ENOG4105DFA	alanine racemase domain protein
BC375_05855	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
BC375_05860	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
BC375_05865	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
BC375_05880	ENOG4105M4H	endoribonuclease L-psp
BC375_05920	ENOG4105VUH	addiction module killer protein
BC375_05925	ENOG4105YES	addiction module antidote protein
BC375_05985	ENOG4106GMR	
BC375_06020	ENOG4108C66	Inherit from COG: DNA primase
BC375_06060	ENOG4105KUS	lysozyme
BC375_06085	ENOG4105CDU	Replicative dna helicase
BC375_06110	ENOG4105WXW	Antirepressor
BC375_06115	ENOG4105WXW	Antirepressor
BC375_06195	ENOG4105H40	
BC375_06220	ENOG4108UUM	single-stranded DNA-binding protein
BC375_06230	ENOG4108J6E	Pfam:Phage_integr_N
BC375_06250	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
BC375_06260	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
BC375_06275	ENOG4105CZX	twitching motility protein
BC375_06280	ENOG4105CZX	twitching motility protein
BC375_06300	ENOG4108NEV	two component transcriptional regulator, LytTR family
BC375_06305	ENOG4108HRK	Histidine kinase
BC375_06315	ENOG4105C3A	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity)
BC375_06330	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
BC375_06345	ENOG4107RVU	D-Ala-D-Ala carboxypeptidase 3 (S13) family
BC375_06355	ENOG4105D7K	pfkb domain protein
BC375_06375	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
BC375_06385	ENOG4108V06	Glutathione peroxidase
BC375_06395	ENOG4105CZV	ABC transporter
BC375_06415	ENOG4105VUH	addiction module killer protein
BC375_06420	ENOG4105YES	addiction module antidote protein
BC375_06435	ENOG4105D4Y	metalloprotease
BC375_06475	ENOG4105VUH	addiction module killer protein
BC375_06480	ENOG4105YES	addiction module antidote protein
BC375_06540	ENOG4106GMR	
BC375_06570	ENOG4108C66	Inherit from COG: DNA primase
BC375_06610	ENOG4105KUS	lysozyme
BC375_06660	ENOG4105C9Q	fumarate hydratase class II
BC375_06670	ENOG4107QTF	adenylosuccinate lyase
BC375_06675	ENOG4105EZE	Cupin 4 family protein
BC375_06680	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
BC375_06685	ENOG4105C7S	Dehydrogenase
BC375_06705	ENOG4105CUZ	uba thif-type nad fad binding protein
BC375_06715	ENOG4105FDS	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
BC375_06720	ENOG4108S0N	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol (By similarity)
BC375_06725	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
BC375_06735	ENOG4105BZN	citrate synthase
BC375_06740	ENOG4105NRA	50s ribosomal protein l31 type b
BC375_06745	ENOG41072GX	Peptidase M22 Glycoprotease
BC375_06750	ENOG4105C5Q	Transcriptional regulator
BC375_06760	ENOG4105D3R	alkyl hydroperoxide reductase
BC375_06770	ENOG4105GVR	general secretion pathway protein D
BC375_06780	ENOG410678M	general secretion pathway protein M
BC375_06785	ENOG41090VX	general secretion pathway protein L
BC375_06790	ENOG4105UV2	general secretion pathway protein K
BC375_06795	ENOG41069G9	General secretion pathway protein J
BC375_06805	ENOG4105WMT	general secretion pathway protein h
BC375_06815	ENOG4105D7Q	type ii secretion system
BC375_06820	ENOG4107QHF	type ii secretion system protein e
BC375_06825	ENOG4105EUR	Domain-Containing protein
BC375_06840	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
BC375_06845	ENOG4108HGY	Proline imino-peptidase
BC375_06860	ENOG4105CSA	Coproporphyrinogen iii oxidase
BC375_06875	ENOG4105DSJ	YicC domain protein
BC375_06880	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
BC375_06885	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
BC375_06890	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
BC375_06895	ENOG4105C11	sulfate adenylyltransferase), subunit 2
BC375_06900	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
BC375_06910	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
BC375_06925	ENOG41063JG	Transcriptional regulator
BC375_06945	ENOG4105CD8	aminopeptidase N
BC375_06950	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
BC375_06960	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
BC375_06980	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
BC375_07005	ENOG4105C3K	feS assembly ATPase SufC
BC375_07015	ENOG4105C9B	Cysteine desulfurase
BC375_07030	ENOG4107QPH	glycogen) synthase
BC375_07035	ENOG4107BJW	polysaccharide deacetylase
BC375_07040	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
BC375_07045	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
BC375_07050	ENOG4105CE4	GlcNAc 6-P deacetylase
BC375_07055	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
BC375_07060	ENOG4105ETE	Transcriptional regulator (LacI family
BC375_07075	ENOG4105CHC	glucokinase (EC 2.7.1.2)
BC375_07090	ENOG4105CAN	Short-chain dehydrogenase reductase Sdr
BC375_07100	ENOG4105BZU	Histidine kinase
BC375_07105	ENOG4105WMR	Protein CrcB homolog
BC375_07110	ENOG4105D1H	recombination factor protein RarA
BC375_07115	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
BC375_07125	ENOG4105CNU	cell division protein FtsK
BC375_07130	ENOG4105C3M	thioredoxin reductase
BC375_07140	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
BC375_07145	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
BC375_07150	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
BC375_07155	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
BC375_07170	ENOG41075W9	High frequency lysogenization protein HflD homolog
BC375_07180	ENOG4108Z33	Thiol disulfide Interchange Protein
BC375_07185	ENOG4108Z33	Thiol disulfide Interchange Protein
BC375_07195	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
BC375_07210	ENOG4105EYW	Ion transport protein
BC375_07215	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
BC375_07265	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
BC375_07275	ENOG4105C2X	Arabinose 5-phosphate isomerase
BC375_07280	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
BC375_07295	ENOG4108IUZ	ABC transporter
BC375_07300	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
BC375_07305	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
BC375_07315	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
BC375_07330	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
BC375_07350	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
BC375_07355	ENOG4108UUM	single-stranded DNA-binding protein
BC375_07360	ENOG4105EAH	synthase
BC375_07365	ENOG4105E2S	oxidase) subunit II
BC375_07370	ENOG4105BZ9	Cytochrome C oxidase, subunit I
BC375_07375	ENOG4105CCU	oxidase (Subunit III)
BC375_07380	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
BC375_07385	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BC375_07400	ENOG4105CQ7	ATP-dependent helicase
BC375_07410	ENOG4105C9U	ATP-dependent DNA helicase RecQ
BC375_07420	ENOG4108M8W	Monooxygenase
BC375_07425	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
BC375_07430	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
BC375_07435	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
BC375_07440	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
BC375_07455	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
BC375_07460	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
BC375_07465	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
BC375_07485	ENOG4107SC1	transglycosylase
BC375_07490	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
BC375_07495	ENOG4107U32	Beta-lactamase domain protein
BC375_07510	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
BC375_07515	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
BC375_07525	ENOG4105NTK	Transcriptional repressor Mpra
BC375_07530	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
BC375_07535	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
BC375_07545	ENOG4108IJ6	ABC transporter
BC375_07555	ENOG4108I5D	sulfate abc transporter
BC375_07560	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
BC375_07570	ENOG4106N3A	copper homeostasis protein cutc
BC375_07580	ENOG4105CX6	glutaminyL-tRNA synthetase
BC375_07585	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
BC375_07595	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
BC375_07600	ENOG4105D49	3-dehydroquinate synthase
BC375_07605	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
BC375_07610	ENOG4105BZU	Histidine kinase
BC375_07615	ENOG4108YYC	ycei family
BC375_07655	ENOG4107QMS	site-determining protein
BC375_07675	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
BC375_07680	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
BC375_07685	ENOG4105CNI	cell division protein FtsW
BC375_07690	ENOG4105CJN	penicillin-binding protein
BC375_07705	ENOG4105DFF	Rod shape-determining protein mreb
BC375_07745	ENOG4105DHJ	ABC, transporter
BC375_07750	ENOG4108SNX	Mammalian cell entry related domain protein
BC375_07765	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
BC375_07775	ENOG4108DG9	Smr protein MutS2
BC375_07780	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
BC375_07785	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
BC375_07790	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
BC375_07795	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
BC375_07800	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
BC375_07815	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
BC375_07835	ENOG4106BRA	Membrane
BC375_07860	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
BC375_07865	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
BC375_07905	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
BC375_07925	ENOG4105DN3	alpha-2-macroglobulin domain protein
BC375_07935	ENOG4105C7F	AcnD-accessory protein PrpF
BC375_07940	ENOG4108I0Z	Aconitate hydratase
BC375_08025	ENOG4108KU3	Integrase
BC375_08030	ENOG4105CR4	methylisocitrate lyase
BC375_08035	ENOG4105MA0	exported protein
BC375_08040	ENOG4105CFU	surface antigen
BC375_08050	ENOG4105CQ7	ATP-dependent helicase
BC375_08070	ENOG4105DA5	(ABC) transporter
BC375_08075	ENOG4105E3A	(ABC) transporter
BC375_08080	ENOG4108JJA	ABC, transporter
BC375_08090	ENOG4108MBX	Secretion Protein
BC375_08100	ENOG4105CI3	gtp-binding protein typa
BC375_08105	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
BC375_08110	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
BC375_08120	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
BC375_08145	ENOG4105I08	Pseudouridine synthase
BC375_08160	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
BC375_08165	ENOG4107QYD	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
BC375_08180	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
BC375_08195	ENOG4105K70	DNA-binding protein
BC375_08205	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
BC375_08210	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
BC375_08215	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
BC375_08230	ENOG4107QQG	Dehydrogenase
BC375_08245	ENOG4105C0P	Mg chelatase subunit ChlI
BC375_08250	ENOG4105W0Z	cytoplasmic protein
BC375_08255	ENOG4108ZT0	50S ribosomal protein l17
BC375_08265	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
BC375_08270	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
BC375_08275	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BC375_08280	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
BC375_08285	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
BC375_08290	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
BC375_08295	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
BC375_08300	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
BC375_08305	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
BC375_08310	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
BC375_08315	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BC375_08320	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
BC375_08325	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
BC375_08330	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
BC375_08335	ENOG41083MP	50s ribosomal protein l29
BC375_08345	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
BC375_08350	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
BC375_08355	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
BC375_08360	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BC375_08365	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
BC375_08370	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
BC375_08375	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
BC375_08385	ENOG4107RAZ	it plays a direct role in the translocation of protons across the membrane (By similarity)
BC375_08390	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
BC375_08395	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
BC375_08400	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
BC375_08405	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
BC375_08410	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
BC375_08415	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
BC375_08420	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
BC375_08430	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
BC375_08445	ENOG4105DQ4	alcohol dehydrogenase
BC375_08460	ENOG4105CC0	LysR family Transcriptional regulator
BC375_08465	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
BC375_08470	ENOG4105N42	UPF0307 protein
BC375_08475	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
BC375_08485	ENOG4105C03	ribonuclease
BC375_08490	ENOG4108Z03	MAF-like protein
BC375_08500	ENOG4105SYT	Methylenetetrahydrofolate reductase
BC375_08505	ENOG4105M6F	mutator MutT protein
BC375_08515	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
BC375_08530	ENOG4105E39	Enoyl-CoA hydratase
BC375_08535	ENOG4105BZU	Histidine kinase
BC375_08540	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
BC375_08545	ENOG4105CRK	lysyL-tRNA synthetase
BC375_08550	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
BC375_08555	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
BC375_08565	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
BC375_08575	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
BC375_08580	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
BC375_08585	ENOG4105C2M	dna polymerase I
BC375_08605	ENOG4105CS1	NAD(P)H quinone oxidoreductase
BC375_08615	ENOG4107RZC	phospholipase d
BC375_08635	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
BC375_08640	ENOG4105BZ1	(ABC) transporter
BC375_08655	ENOG4108EC8	DNA internalization-related competence protein ComEC
BC375_08660	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
BC375_08665	ENOG4105D60	lipoprotein releasing system transmembrane protein
BC375_08705	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
BC375_08710	ENOG4108IJ9	(ABC) transporter
BC375_08715	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
BC375_08720	ENOG4105CHC	glucokinase (EC 2.7.1.2)
BC375_08725	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
BC375_08730	ENOG4105C01	Dihydroxy-acid dehydratase
BC375_08735	ENOG4108UHU	Aldolase
BC375_08760	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
BC375_08785	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
BC375_08790	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
BC375_08795	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
BC375_08800	ENOG4105KNE	Phosphatidate cytidylyltransferase
BC375_08810	ENOG4105DZP	Membrane-associated zinc metalloprotease
BC375_08815	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BC375_08820	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
BC375_08825	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
BC375_08830	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
BC375_08835	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
BC375_08840	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
BC375_08850	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
BC375_08865	ENOG4105E55	glycerol-3-phosphate acyltransferase
BC375_08890	ENOG4105C29	acyl-CoA thioesterase
BC375_08900	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
BC375_08905	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
BC375_08910	ENOG4105KST	dependent repressor
BC375_08915	ENOG4108Z6B	deaminase
BC375_08950	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
BC375_08955	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
BC375_08960	ENOG4105CH7	arginosuccinase
BC375_08970	ENOG4105CAS	nag kinase
BC375_08980	ENOG4105CDH	Citrulline--aspartate ligase
BC375_08985	ENOG4105DBV	ornithine carbamoyltransferase
BC375_08995	ENOG4105C8N	cysteinyl-tRNA synthetase
BC375_09000	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
BC375_09005	ENOG4105E8G	Major facilitator Superfamily
BC375_09015	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BC375_09020	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
BC375_09025	ENOG4105CD3	dihydroorotase
BC375_09035	ENOG4105BZU	Histidine kinase
BC375_09045	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
BC375_09055	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
BC375_09060	ENOG4106H78	methyltransferase
BC375_09065	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
BC375_09070	ENOG4105C6K	Malic enzyme
BC375_09075	ENOG4105CK2	sodium dicarboxylate symporter
BC375_09090	ENOG4105BZU	Histidine kinase
BC375_09125	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
BC375_09150	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BC375_09170	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
BC375_09175	ENOG4107YIM	Involved in the transcription termination process (By similarity)
BC375_09185	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
BC375_09195	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
BC375_09215	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
BC375_09220	ENOG4105C5H	ABC transporter
BC375_09230	ENOG4105KIR	Thiol-disulfide oxidoreductase dcc
BC375_09240	ENOG4105C34	Pseudouridine synthase
BC375_09245	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BC375_09255	ENOG4105CE1	Ferrous iron transport protein b
BC375_09275	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
BC375_09285	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
BC375_09300	ENOG4105C79	DNA protecting protein DprA
BC375_09305	ENOG4108RPN	Protein smg homolog
BC375_09315	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
BC375_09320	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
BC375_09350	ENOG4105KB2	stringent starvation protein b
BC375_09355	ENOG4107MKT	Stringent starvation protein a
BC375_09360	ENOG4105EIX	cytochrome c1
BC375_09365	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
BC375_09370	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
BC375_09380	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
BC375_09385	ENOG4105C9A	Phoh family
BC375_09390	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
BC375_09400	ENOG4108JU5	Magnesium and cobalt efflux protein
BC375_09525	ENOG4105BZ4	penicillin-binding protein
BC375_09535	ENOG4105DVT	helicase
BC375_09545	ENOG41077A9	carbonic anhydrase
BC375_09560	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
BC375_09570	ENOG4105D01	(LipO)protein
BC375_09580	ENOG4107QSN	dihydrolipoamide acetyltransferase
BC375_09585	ENOG4107QSN	dihydrolipoamide acetyltransferase
BC375_09590	ENOG4107QN2	dihydrolipoyl dehydrogenase
BC375_09605	ENOG4105C28	cystathionine
BC375_09610	ENOG4106TYC	homoserine o-acetyltransferase (EC 2.3.1.31)
BC375_09615	ENOG4105DR5	peptidase
BC375_09620	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
BC375_09625	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
BC375_09630	ENOG4108UM1	dedA family
BC375_09635	ENOG4108K5P	(LipO)protein
BC375_09645	ENOG4105BZU	Histidine kinase
BC375_09650	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
BC375_09655	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
BC375_09660	ENOG4105E0X	reductase
BC375_09665	ENOG4105VRS	hydrolase family 18
BC375_09695	ENOG4105CWX	Alpha-1,2-mannosidase
BC375_09705	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
BC375_09710	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
BC375_09715	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
BC375_09725	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
BC375_09735	ENOG4107R11	Transcriptional regulator
BC375_09765	ENOG4107R1Y	fructose-bisphosphate aldolase
BC375_09770	ENOG4105CA9	Pyruvate kinase
BC375_09775	ENOG4105BZA	Phosphoglycerate kinase
BC375_09780	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
BC375_09785	ENOG4105MYN	Zinc uptake regulation protein
BC375_09795	ENOG4106R7G	Glycoside hydrolase family 5
BC375_09815	ENOG4108YQE	rare lipoprotein a
BC375_09820	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
BC375_09825	ENOG4105DR5	peptidase
BC375_09835	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
BC375_09845	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
BC375_09850	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
BC375_09855	ENOG4105CPF	Cell wall formation (By similarity)
BC375_09860	ENOG4105DFU	Cell wall formation (By similarity)
BC375_09865	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
BC375_09875	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
BC375_09880	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
BC375_09885	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
BC375_09890	ENOG4105CJN	penicillin-binding protein
BC375_09895	ENOG4106932	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
BC375_09900	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
BC375_09920	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
BC375_09930	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
BC375_09955	ENOG4105EXC	Acyl-transferase
BC375_09985	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
BC375_10015	ENOG41080HT	Transcriptional regulator, arsr family
BC375_10020	ENOG4105MD1	YeeE YedE family protein
BC375_10025	ENOG4105KFG	YeeE YedE family protein
BC375_10030	ENOG4108VCT	Sulfite exporter TauE/SafE
BC375_10035	ENOG4105DHP	deoxycytidine triphosphate deaminase
BC375_10045	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
BC375_10050	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
BC375_10055	ENOG4105K8N	protein family UPF0079, ATPase
BC375_10060	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
BC375_10095	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
BC375_10110	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
BC375_10115	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
BC375_10120	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
BC375_10125	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
BC375_10135	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
BC375_10140	ENOG4105C22	threonyL-tRNA synthetase
BC375_10165	ENOG4105ETX	regulatoR
BC375_10175	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
BC375_10180	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
BC375_10210	ENOG4107QHF	type ii secretion system protein e
BC375_10215	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
BC375_10220	ENOG4107TUY	Histidine kinase
BC375_10230	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
BC375_10240	ENOG4105D5K	Hemolysin activator protein
BC375_10250	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
BC375_10265	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
BC375_10285	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
BC375_10295	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
BC375_10300	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
BC375_10310	ENOG4108Z4V	iron-sulfur cluster assembly
BC375_10315	ENOG4105C5S	asparaginyl-tRNA synthetase
BC375_10340	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
BC375_10345	ENOG4105D4A	Cell wall formation (By similarity)
BC375_10350	ENOG4108SXK	Transporter Drug Metabolite Exporter family
BC375_10360	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
BC375_10370	ENOG4108UYB	regulatoR
BC375_10375	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
BC375_10390	ENOG4105BZ1	(ABC) transporter
BC375_10395	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
BC375_10400	ENOG4105DFG	type I secretion outer membrane protein
BC375_10405	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
BC375_10410	ENOG4105C9X	ppx gppa phosphatase
BC375_10415	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
BC375_10420	ENOG4105BZU	Histidine kinase
BC375_10425	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
BC375_10435	ENOG4105VW4	glutaredoxin 3
BC375_10440	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
BC375_10450	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
BC375_10460	ENOG4108Z4U	Ferredoxin
BC375_10470	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
BC375_10475	ENOG41090A4	Pterin carbinolamine dehydratase
BC375_10490	ENOG4105C03	ribonuclease
BC375_10500	ENOG4105C72	UPF0176 protein
BC375_10510	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
BC375_10525	ENOG4105C5H	ABC transporter
BC375_10535	ENOG4105CNG	UPF0061 protein
BC375_10550	ENOG4105D0M	Protease HtpX homolog
BC375_10555	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
BC375_10560	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
BC375_10565	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
BC375_10570	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
BC375_10575	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
BC375_10580	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
BC375_10585	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
BC375_10590	ENOG4108VZM	50s ribosomal protein L10
BC375_10595	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
BC375_10600	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
BC375_10605	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
BC375_10610	ENOG4105PM1	preprotein translocase subunit SecE
BC375_10620	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
BC375_10640	ENOG4105C3G	gtp-binding protein
BC375_10645	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
BC375_10665	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
BC375_10670	ENOG4108D76	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
BC375_10675	ENOG4105DJQ	tetratricopeptide tpr_2 repeat protein
BC375_10680	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
BC375_10685	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
BC375_10690	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
BC375_10720	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
BC375_10725	ENOG4105M2J	Glutaredoxin
BC375_10730	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
BC375_10735	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
BC375_10740	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
BC375_10750	ENOG4107STQ	Multicopper oxidase
BC375_10760	ENOG4105C4R	Atp-dependent dna helicase
BC375_10765	ENOG4105DJ9	glucan biosynthesis protein
BC375_10775	ENOG4107QI1	Mate efflux family protein
BC375_10795	ENOG4105C25	Primosomal protein n'
BC375_10805	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
BC375_10810	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
BC375_10815	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
BC375_10820	ENOG4105CAK	Cell division ATP-binding protein ftsE
BC375_10825	ENOG4105C1J	atp-dependent rna helicase
BC375_10830	ENOG4105K63	Thioredoxin
BC375_10835	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
BC375_10840	ENOG4105E9K	Isocitrate dehydrogenase
BC375_10850	ENOG4105CN1	protease
BC375_10855	ENOG41063SB	peptidase
BC375_10870	ENOG4105BZ8	glutamate synthase
BC375_10880	ENOG4105II7	pyrroline-5-carboxylate reductase
BC375_10905	ENOG4105UBK	short-chain dehydrogenase reductase
BC375_10930	ENOG4105DZR	Type I site-specific deoxyribonuclease
BC375_10955	ENOG41082EK	Restriction modification system DNA (Specificity
BC375_10975	ENOG410829K	Lysine exporter protein (Lyse ygga)
BC375_10985	ENOG4105E7D	Protein of unknown function (DUF3375)
BC375_11015	ENOG4105DZR	Type I site-specific deoxyribonuclease
BC375_11025	ENOG4105CVR	type I restriction-modification system
BC375_11105	ENOG4105YES	addiction module antidote protein
BC375_11110	ENOG4105VUH	addiction module killer protein
BC375_11235	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
BC375_11245	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
BC375_11250	ENOG4107FTS	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
BC375_11295	ENOG4105VUH	addiction module killer protein
BC375_11300	ENOG4105X54	addiction module antidote protein
BC375_11310	ENOG4108C33	Resolvase
BC375_11325	ENOG4108IYH	Dna topoisomerase
BC375_11405	ENOG4108UUM	single-stranded DNA-binding protein