locus-tag	class	description
IUD20_00010	COG0592	DNA-directed DNA polymerase activity
IUD20_00020	COG0187	DNA topoisomerase II activity
IUD20_00030	COG0501	Belongs to the peptidase M48B family
IUD20_00060	COG4946	Tricorn protease homolog
IUD20_00060	COG0823	Involved in the tonB-independent uptake of proteins
IUD20_00060	COG1506	peptidase
IUD20_00090	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IUD20_00150	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
IUD20_00160	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IUD20_00170	COG0511	ligase activity, forming carbon-carbon bonds
IUD20_00175	COG0439	Biotin carboxylase
IUD20_00180	COG0210	DNA helicase
IUD20_00210	COG1040	competence protein
IUD20_00220	COG1752	Esterase of the alpha-beta hydrolase superfamily
IUD20_00260	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
IUD20_00270	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IUD20_00295	COG3121	Chaperone
IUD20_00300	COG3539	Fimbrial protein
IUD20_00310	COG1546	Belongs to the CinA family
IUD20_00315	COG0477	Major facilitator Superfamily
IUD20_00320	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IUD20_00335	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IUD20_00340	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IUD20_00350	COG1534	Rna-binding protein
IUD20_00380	COG1560	Kdo2-lipid A biosynthetic process
IUD20_00385	COG1519	Transferase
IUD20_00425	COG1393	Belongs to the ArsC family
IUD20_00435	COG0367	asparagine synthase
IUD20_00445	COG2070	2-Nitropropane dioxygenase
IUD20_00475	COG0339	signal peptide processing
IUD20_00490	COG2132	Multicopper oxidase
IUD20_00520	COG0795	lipopolysaccharide-transporting ATPase activity
IUD20_00555	COG4221	oxidoreductase activity
IUD20_00575	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IUD20_00585	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IUD20_00640	COG2223	nitrite transmembrane transporter activity
IUD20_00650	COG0739	heme binding
IUD20_00685	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
IUD20_00700	COG1028	Short-chain dehydrogenase reductase Sdr
IUD20_00710	COG1272	protein, Hemolysin III
IUD20_00715	COG0463	Glycosyl transferase, family 2
IUD20_00720	COG0084	hydrolase, TatD family'
IUD20_00750	COG0330	HflC and HflK could
IUD20_00755	COG3956	TIGRFAM MazG family protein
IUD20_00760	COG1218	3'(2'),5'-bisphosphate nucleotidase
IUD20_00765	COG0494	nUDIX hydrolase
IUD20_00775	COG1385	rRNA (uridine-N3-)-methyltransferase activity
IUD20_00780	COG0513	Belongs to the DEAD box helicase family
IUD20_00785	COG0720	synthase
IUD20_00810	COG1981	membrane
IUD20_00845	COG0512	Glutamine amidotransferase of anthranilate synthase
IUD20_00875	COG0006	proline dipeptidase activity
IUD20_00895	COG1862	Preprotein translocase
IUD20_00900	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IUD20_00905	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IUD20_00915	COG0617	tRNA 3'-terminal CCA addition
IUD20_00955	COG0195	Participates in both transcription termination and antitermination
IUD20_00985	COG1733	regulation of RNA biosynthetic process
IUD20_00990	COG0702	epimerase
IUD20_01035	COG2086	electron transfer activity
IUD20_01065	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IUD20_01095	COG0477	Major facilitator Superfamily
IUD20_01115	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IUD20_01120	COG0671	phosphoesterase, PA-phosphatase related
IUD20_01135	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IUD20_01140	COG0628	permease
IUD20_01160	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IUD20_01165	COG1090	epimerase
IUD20_01170	COG0318	PFAM AMP-dependent synthetase and ligase
IUD20_01190	COG1049	propionate catabolic process, 2-methylcitrate cycle
IUD20_01235	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IUD20_01260	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IUD20_01280	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
IUD20_01285	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
IUD20_01290	COG1034	ATP synthesis coupled electron transport
IUD20_01325	COG1007	ATP synthesis coupled electron transport
IUD20_01330	COG1028	Short-chain dehydrogenase reductase Sdr
IUD20_01335	COG2851	Citrate transporter
IUD20_01350	COG0642	Histidine kinase
IUD20_01365	COG0784	Response regulator, receiver
IUD20_01365	COG2205	protein histidine kinase activity
IUD20_01385	COG0281	malic enzyme
IUD20_01385	COG0280	phosphate acetyltransferase
IUD20_01395	COG0742	ribosomal rna small subunit methyltransferase
IUD20_01415	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IUD20_01435	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
IUD20_01460	COG2166	iron-sulfur cluster assembly
IUD20_01485	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IUD20_01560	COG1321	iron dependent repressor
IUD20_01580	COG1946	Acyl-CoA thioesterase
IUD20_01665	COG0575	Belongs to the CDS family
IUD20_01760	COG0354	folic acid binding
IUD20_01770	COG2009	succinate dehydrogenase
IUD20_01775	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
IUD20_01785	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
IUD20_01815	COG0811	peptide transport
IUD20_01865	COG3093	addiction module antidote protein HigA
IUD20_01875	COG2944	sequence-specific DNA binding
IUD20_01940	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
IUD20_01960	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IUD20_02030	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
IUD20_02055	COG1024	Enoyl-CoA hydratase
IUD20_02060	COG0019	diaminopimelate decarboxylase activity
IUD20_02080	COG0494	nUDIX hydrolase
IUD20_02085	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
IUD20_02110	COG0312	modulator of DNA gyrase
IUD20_02120	COG0312	modulator of DNA gyrase
IUD20_02125	COG0583	DNA-binding transcription factor activity
IUD20_02140	COG1064	alcohol dehydrogenase
IUD20_02195	COG0356	it plays a direct role in the translocation of protons across the membrane
IUD20_02315	COG0201	protein transport
IUD20_02345	COG2960	long-chain fatty acid transporting porin activity
IUD20_02350	COG0606	chelatase, subunit chli
IUD20_02375	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
IUD20_02435	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IUD20_02440	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IUD20_02455	COG1187	pseudouridine synthase activity
IUD20_02460	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IUD20_02480	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IUD20_02485	COG0625	glutathione transferase activity
IUD20_02495	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IUD20_02500	COG1217	gtp-binding protein TYPA
IUD20_02540	COG0842	Transport permease protein
IUD20_02545	COG1131	(ABC) transporter
IUD20_02565	COG1643	Atp-dependent helicase
IUD20_02575	COG1956	GAF domain-containing protein
IUD20_02580	COG0729	surface antigen
IUD20_02585	COG2911	Protein conserved in bacteria
IUD20_02595	COG0582	viral genome integration into host DNA
IUD20_02765	COG0668	transmembrane transport
IUD20_02795	COG5297	Belongs to the glycosyl hydrolase family 6
IUD20_02830	COG2733	membrane
IUD20_02835	COG1253	flavin adenine dinucleotide binding
IUD20_02900	COG0644	oxidoreductase
IUD20_02900	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
IUD20_02915	COG3218	ABC-type transport auxiliary lipoprotein component
IUD20_02915	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
IUD20_02920	COG1127	ABC transporter
IUD20_02925	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
IUD20_02960	COG1077	Cell shape determining protein MreB Mrl
IUD20_02965	COG1792	Involved in formation and maintenance of cell shape
IUD20_02970	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
IUD20_02975	COG0768	penicillin binding
IUD20_02980	COG0772	Belongs to the SEDS family
IUD20_02990	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IUD20_03010	COG2894	cell division
IUD20_03030	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
IUD20_03045	COG2353	YceI-like domain
IUD20_03115	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
IUD20_03120	COG4208	sulfate ABC transporter
IUD20_03145	COG1846	Transcriptional regulator
IUD20_03185	COG0741	lytic transglycosylase activity
IUD20_03195	COG1999	signal sequence binding
IUD20_03220	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IUD20_03255	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IUD20_03265	COG0514	ATP-dependent DNA helicase (RecQ)
IUD20_03270	COG0783	Belongs to the Dps family
IUD20_03275	COG1643	Atp-dependent helicase
IUD20_03285	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
IUD20_03290	COG1845	cytochrome c oxidase, subunit III
IUD20_03295	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IUD20_03300	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
IUD20_03305	COG0142	geranyltranstransferase activity
IUD20_03320	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IUD20_03340	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IUD20_03375	COG1137	ATPase activity
IUD20_03390	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
IUD20_03400	COG0271	Belongs to the BolA IbaG family
IUD20_03440	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IUD20_03450	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IUD20_03485	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IUD20_03515	COG0542	response to heat
IUD20_03535	COG0492	ferredoxin-NADP+ reductase activity
IUD20_03555	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
IUD20_03565	COG4191	Histidine kinase
IUD20_03570	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IUD20_03575	COG1028	Short-chain dehydrogenase reductase Sdr
IUD20_03605	COG1609	Transcriptional regulator
IUD20_03610	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IUD20_03615	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
IUD20_03620	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IUD20_03630	COG0726	polysaccharide deacetylase
IUD20_03635	COG0297	glycogen (starch) synthase activity
IUD20_03655	COG0719	Fe-S assembly protein
IUD20_03660	COG0396	ATPase activity
IUD20_03665	COG0719	Fe-S assembly protein
IUD20_03670	COG1959	2 iron, 2 sulfur cluster binding
IUD20_03725	COG0308	aminopeptidase N
IUD20_03775	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
IUD20_03800	COG1561	YicC-like family, N-terminal region
IUD20_03815	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IUD20_03850	COG5295	Hep Hag repeat protein
IUD20_03855	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IUD20_03860	COG1459	type II secretion system
IUD20_03865	COG2165	general secretion pathway protein
IUD20_03870	COG4970	Tfp pilus assembly protein FimT
IUD20_03875	COG2165	general secretion pathway protein
IUD20_03880	COG4795	General secretion pathway protein
IUD20_03885	COG3156	type II secretion system protein K
IUD20_03890	COG3166	PFAM Fimbrial assembly family protein
IUD20_03905	COG1450	Type ii and iii secretion system protein
IUD20_03920	COG3634	alkyl hydroperoxide reductase activity
IUD20_03925	COG0583	DNA-binding transcription factor activity
IUD20_03985	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
IUD20_04010	COG0567	Dehydrogenase, E1 component
IUD20_04015	COG2850	peptidyl-arginine hydroxylation
IUD20_04030	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
IUD20_04130	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IUD20_04135	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IUD20_04140	COG2902	Dehydrogenase
IUD20_04180	COG2925	Exonuclease
IUD20_04190	COG0025	NhaP-type Na H and K H
IUD20_04210	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IUD20_04235	COG0006	proline dipeptidase activity
IUD20_04245	COG0778	Nitroreductase
IUD20_04280	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IUD20_04320	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IUD20_04330	COG0557	exoribonuclease II activity
IUD20_04340	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
IUD20_04355	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
IUD20_04360	COG1289	transmembrane transporter activity
IUD20_04380	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
IUD20_04390	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IUD20_04405	COG0596	Alpha beta hydrolase
IUD20_04410	COG0727	PFAM Uncharacterised protein family (UPF0153)
IUD20_04455	COG0840	transmembrane signaling receptor activity
IUD20_04460	COG0643	Histidine kinase
IUD20_04460	COG0784	Response regulator, receiver
IUD20_04460	COG2198	Histidine kinase
IUD20_04490	COG0285	dihydrofolate synthase activity
IUD20_04500	COG0339	signal peptide processing
IUD20_04520	COG1301	dicarboxylic acid transport
IUD20_04525	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IUD20_04535	COG2091	lysine biosynthetic process via aminoadipic acid
IUD20_04575	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IUD20_04605	COG0512	Glutamine amidotransferase of anthranilate synthase
IUD20_04605	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IUD20_04625	COG0084	hydrolase, TatD family'
IUD20_04645	COG0552	protein localization to endoplasmic reticulum
IUD20_04690	COG0824	Thioesterase
IUD20_04715	COG2885	chlorophyll binding
IUD20_04725	COG0602	queuosine metabolic process
IUD20_04745	COG0386	Belongs to the glutathione peroxidase family
IUD20_04765	COG0406	alpha-ribazole phosphatase activity
IUD20_05135	COG0675	Transposase, IS605 OrfB family
IUD20_05295	COG2369	cell adhesion
IUD20_05330	COG3210	domain, Protein
IUD20_05345	COG0582	viral genome integration into host DNA
IUD20_05350	COG3567	Phage-associated protein, HI1409 family
IUD20_05355	COG5410	chromosome segregation
IUD20_05380	COG3772	lysozyme
IUD20_05415	COG3617	BRO family, N-terminal domain
IUD20_05500	COG5532	Uncharacterized conserved protein (DUF2303)
IUD20_05530	COG0629	single-stranded DNA binding
IUD20_05540	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
IUD20_05545	COG3852	Histidine kinase
IUD20_05550	COG2204	response regulator
IUD20_05565	COG0004	ammonium transporteR
IUD20_05570	COG0347	Belongs to the P(II) protein family
IUD20_05575	COG0174	glutamine synthetase
IUD20_05585	COG2353	YceI-like domain
IUD20_05640	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
IUD20_05645	COG1764	response to oxidative stress
IUD20_05650	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IUD20_05695	COG1399	metal-binding, possibly nucleic acid-binding protein
IUD20_05705	COG0714	Associated with various cellular activities
IUD20_05725	COG0537	adenosine 5'-monophosphoramidase activity
IUD20_05740	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IUD20_05780	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IUD20_05805	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
IUD20_05805	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
IUD20_05855	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IUD20_05870	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IUD20_05885	COG0251	oxidation-reduction process
IUD20_05950	COG3077	Addiction module antitoxin, RelB DinJ family
IUD20_05955	COG3041	Addiction module toxin RelE StbE family
IUD20_06025	COG3772	lysozyme
IUD20_06090	COG4197	protein conserved in bacteria, prophage-related
IUD20_06160	COG3617	BRO family, N-terminal domain
IUD20_06200	COG0392	lysyltransferase activity
IUD20_06200	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IUD20_06210	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IUD20_06220	COG0463	Glycosyl transferase, family 2
IUD20_06265	COG3275	phosphorelay sensor kinase activity
IUD20_06270	COG0400	carboxylic ester hydrolase activity
IUD20_06290	COG2226	methyltransferase
IUD20_06315	COG2027	D-alanyl-D-alanine carboxypeptidase
IUD20_06325	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IUD20_06355	COG0386	Belongs to the glutathione peroxidase family
IUD20_06360	COG1131	(ABC) transporter
IUD20_06390	COG3657	addiction module killer protein
IUD20_06395	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IUD20_06500	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
IUD20_06505	COG0488	(ABC) transporter
IUD20_06515	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
IUD20_06525	COG4651	solute:proton antiporter activity
IUD20_06525	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IUD20_06585	COG0859	PFAM glycosyl transferase family 9
IUD20_06600	COG0631	protein serine/threonine phosphatase activity
IUD20_06605	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IUD20_06635	COG2183	response to ionizing radiation
IUD20_06650	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
IUD20_06655	COG3118	belongs to the thioredoxin family
IUD20_06700	COG2951	lytic endotransglycosylase activity
IUD20_06705	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
IUD20_06820	COG0277	FAD linked oxidase domain protein
IUD20_06825	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IUD20_06830	COG0531	amino acid
IUD20_06920	COG0527	aspartate kinase activity
IUD20_06920	COG0460	homoserine dehydrogenase
IUD20_06940	COG1686	Belongs to the peptidase S11 family
IUD20_06965	COG4953	penicillin-binding protein 1C
IUD20_06990	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IUD20_07055	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IUD20_07060	COG1506	peptidase
IUD20_07060	COG0823	Involved in the tonB-independent uptake of proteins
IUD20_07065	COG1297	OPT oligopeptide transporter protein
IUD20_07095	COG0676	glucose-6-phosphate 1-epimerase activity
IUD20_07105	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IUD20_07110	COG1335	isochorismatase
IUD20_07115	COG0318	PFAM AMP-dependent synthetase and ligase
IUD20_07125	COG0463	Glycosyl transferase, family 2
IUD20_07140	COG1192	Involved in chromosome partitioning
IUD20_07200	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IUD20_07245	COG0489	protein tyrosine kinase activity
IUD20_07255	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IUD20_07350	COG0077	Prephenate dehydratase
IUD20_07350	COG1605	Chorismate mutase
IUD20_07365	COG1668	transmembrane transport
IUD20_07370	COG4555	ABC transporter
IUD20_07395	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
IUD20_07405	COG1605	Chorismate mutase
IUD20_07405	COG0287	Prephenate dehydrogenase
IUD20_07440	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IUD20_07465	COG1278	Cold shock
IUD20_07475	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
IUD20_07485	COG2954	triphosphatase activity
IUD20_07500	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
IUD20_07505	COG0438	transferase activity, transferring glycosyl groups
IUD20_07515	COG0438	transferase activity, transferring glycosyl groups
IUD20_07580	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IUD20_07585	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IUD20_07600	COG1064	alcohol dehydrogenase
IUD20_07615	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
IUD20_07625	COG0436	Aminotransferase
IUD20_07705	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
IUD20_07705	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IUD20_07755	COG0196	riboflavin kinase activity
IUD20_07760	COG0728	peptidoglycan biosynthetic process
IUD20_07765	COG0268	Binds directly to 16S ribosomal RNA
IUD20_07815	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IUD20_07830	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
IUD20_07885	COG0395	ABC-type sugar transport system, permease component
IUD20_07890	COG1175	transmembrane transport
IUD20_07920	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IUD20_07940	COG0436	Aminotransferase
IUD20_08000	COG5434	Belongs to the glycosyl hydrolase 28 family
IUD20_08025	COG0402	S-adenosylhomocysteine deaminase activity
IUD20_08035	COG1509	lysine 2,3-aminomutase activity
IUD20_08070	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IUD20_08075	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IUD20_08090	COG1028	Short-chain dehydrogenase reductase Sdr
IUD20_08140	COG0142	geranyltranstransferase activity
IUD20_08165	COG1301	dicarboxylic acid transport
IUD20_08175	COG0791	NLP P60 protein
IUD20_08180	COG0791	NLP P60 protein
IUD20_08190	COG2311	Membrane
IUD20_08205	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IUD20_08260	COG0351	phosphomethylpyrimidine kinase
IUD20_08260	COG0352	thiamine-phosphate diphosphorylase activity
IUD20_08270	COG1324	tolerance protein
IUD20_08305	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IUD20_08310	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IUD20_08315	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
IUD20_08330	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IUD20_08350	COG4774	siderophore transport
IUD20_08375	COG1477	protein flavinylation
IUD20_08380	COG1555	photosystem II stabilization
IUD20_08385	COG3178	'Phosphotransferase
IUD20_08390	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
IUD20_08400	COG0628	permease
IUD20_08420	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IUD20_08445	COG3590	peptidase
IUD20_08495	COG0805	protein transport
IUD20_08505	COG0519	Catalyzes the synthesis of GMP from XMP
IUD20_08505	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IUD20_08515	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
IUD20_08530	COG3107	peptidoglycan biosynthetic process
IUD20_08555	COG2878	Part of a membrane complex involved in electron transport
IUD20_08630	COG0629	single-stranded DNA binding
IUD20_08660	COG0827	DNA restriction-modification system
IUD20_08665	COG0827	DNA restriction-modification system
IUD20_08705	COG4968	Prepilin-type N-terminal cleavage methylation domain
IUD20_08710	COG1611	Belongs to the LOG family
IUD20_08715	COG4943	cyclic-guanylate-specific phosphodiesterase activity
IUD20_08720	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
IUD20_08730	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IUD20_08760	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IUD20_08775	COG0330	HflC and HflK could
IUD20_08780	COG0330	HflC and HflK could
IUD20_08785	COG0604	alcohol dehydrogenase
IUD20_08815	COG1183	phosphatidylcholine synthase activity
IUD20_08835	COG0668	transmembrane transport
IUD20_08840	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IUD20_08855	COG1610	YqeY-like protein
IUD20_08865	COG0358	DNA primase activity
IUD20_08900	COG1074	ATP-dependent DNA helicase activity
IUD20_08905	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
IUD20_08910	COG1127	ABC transporter
IUD20_08915	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
IUD20_08935	COG2853	Lipoprotein
IUD20_08945	COG1116	anion transmembrane transporter activity
IUD20_08955	COG0531	amino acid
IUD20_08960	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
IUD20_08965	COG0861	Integral membrane protein TerC family
IUD20_09000	COG2193	ferroxidase activity
IUD20_09090	COG2194	sulfuric ester hydrolase activity
IUD20_09130	COG0667	Aldo Keto reductase
IUD20_09135	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IUD20_09145	COG0305	Participates in initiation and elongation during chromosome replication
IUD20_09175	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IUD20_09185	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IUD20_09190	COG0277	FAD linked oxidase domain protein
IUD20_09205	COG4206	TonB-dependent receptor
IUD20_09305	COG3617	BRO family, N-terminal domain
IUD20_09375	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IUD20_09395	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
IUD20_09420	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IUD20_09420	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IUD20_09440	COG0488	(ABC) transporter
IUD20_09450	COG3011	Protein conserved in bacteria
IUD20_09475	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
IUD20_09475	COG1918	ferrous iron import across plasma membrane
IUD20_09485	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IUD20_09510	COG0758	DNA mediated transformation
IUD20_09555	COG2969	positive regulation of protein catabolic process
IUD20_09560	COG0625	glutathione transferase activity
IUD20_09565	COG2857	Cytochrome c1
IUD20_09570	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
IUD20_09575	COG0723	plastoquinol--plastocyanin reductase activity
IUD20_09580	COG0741	lytic transglycosylase activity
IUD20_09590	COG1702	phosphate starvation-inducible protein PhoH
IUD20_09605	COG4535	Mg2 and Co2 transporter CorC
IUD20_09615	COG0598	Magnesium transport protein CorA
IUD20_09670	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IUD20_09680	COG1199	ATP-dependent helicase activity
IUD20_09690	COG0288	reversible hydration of carbon dioxide
IUD20_09715	COG2011	ABC-type metal ion transport system permease component
IUD20_09735	COG0508	dehydrogenase complex catalyzes the overall conversion of
IUD20_09740	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IUD20_09755	COG0626	cystathionine gamma-synthase activity
IUD20_09760	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IUD20_09765	COG0739	heme binding
IUD20_09785	COG1238	metal cluster binding
IUD20_09800	COG5002	protein histidine kinase activity
IUD20_09820	COG1388	LysM domain
IUD20_09820	COG3858	chitin binding
IUD20_09825	COG3525	Glycosyl hydrolase, family 20, catalytic domain
IUD20_09835	COG1472	Belongs to the glycosyl hydrolase 3 family
IUD20_09850	COG3537	Alpha-1,2-mannosidase
IUD20_09875	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IUD20_09880	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IUD20_09925	COG0469	pyruvate kinase activity
IUD20_09945	COG0735	belongs to the Fur family
IUD20_09955	COG5297	Belongs to the glycosyl hydrolase family 6
IUD20_09955	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
IUD20_09980	COG4305	rare lipoprotein A
IUD20_09990	COG0739	heme binding
IUD20_10005	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IUD20_10015	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
IUD20_10045	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
IUD20_10060	COG3116	cell division
IUD20_10075	COG0471	metal ion transport
IUD20_10075	COG3273	potassium ion transport
IUD20_10130	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
IUD20_10190	COG0860	N-Acetylmuramoyl-L-alanine amidase
IUD20_10195	COG0802	atpase or kinase
IUD20_10200	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
IUD20_10200	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IUD20_10300	COG0745	RESPONSE REGULATOR receiver
IUD20_10305	COG0642	Histidine kinase
IUD20_10315	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
IUD20_10360	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
IUD20_10370	COG2831	hemolysin activation secretion protein
IUD20_10395	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
IUD20_10435	COG0316	Belongs to the HesB IscA family
IUD20_10475	COG0697	spore germination
IUD20_10480	COG0671	phosphoesterase, PA-phosphatase related
IUD20_10495	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
IUD20_10515	COG1132	(ABC) transporter
IUD20_10520	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
IUD20_10525	COG1538	Outer membrane efflux protein
IUD20_10550	COG0745	RESPONSE REGULATOR receiver
IUD20_10555	COG4783	chaperone-mediated protein folding
IUD20_10565	COG0473	3-isopropylmalate dehydrogenase activity
IUD20_10575	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IUD20_10580	COG3083	sulfuric ester hydrolase activity
IUD20_10585	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
IUD20_10610	COG0564	pseudouridine synthase activity
IUD20_10615	COG1530	ribonuclease E activity
IUD20_10620	COG2197	response regulator
IUD20_10635	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IUD20_10650	COG0488	(ABC) transporter
IUD20_10665	COG1278	Cold shock
IUD20_10765	COG0012	GTP binding
IUD20_10855	COG2095	MarC family integral membrane protein
IUD20_10865	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
IUD20_10890	COG2132	Multicopper oxidase
IUD20_10900	COG0210	DNA helicase
IUD20_10910	COG0616	signal peptide processing
IUD20_10930	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IUD20_10950	COG2201	protein-glutamate methylesterase activity
IUD20_10955	COG2177	Part of the ABC transporter FtsEX involved in
IUD20_10960	COG2884	Cell division ATP-binding protein ftsE
IUD20_10970	COG3118	belongs to the thioredoxin family
IUD20_10975	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
IUD20_10990	COG0793	Belongs to the peptidase S41A family
IUD20_10995	COG4942	peptidase
IUD20_11010	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
IUD20_11015	COG0493	'glutamate synthase
IUD20_11020	COG0067	glutamate synthase
IUD20_11020	COG0070	glutamate synthase
IUD20_11020	COG0069	glutamate synthase activity
IUD20_11070	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
IUD20_11120	COG4942	peptidase
IUD20_11265	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IUD20_11270	COG3657	addiction module killer protein
IUD20_11380	COG3451	type IV secretory pathway VirB4
IUD20_11435	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
IUD20_11540	COG0675	Transposase, IS605 OrfB family
IUD20_11560	COG0629	single-stranded DNA binding
IUD20_11570	COG4962	Type ii secretion system protein e