locus-tag	class	description
XFLM_00005	COG0488	(ABC) transporter
XFLM_00015	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
XFLM_00025	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
XFLM_00025	COG4651	solute:proton antiporter activity
XFLM_00090	COG0859	PFAM glycosyl transferase family 9
XFLM_00100	COG0631	protein serine/threonine phosphatase activity
XFLM_00105	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
XFLM_00130	COG2183	response to ionizing radiation
XFLM_00145	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
XFLM_00150	COG3118	belongs to the thioredoxin family
XFLM_00195	COG2951	lytic endotransglycosylase activity
XFLM_00200	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
XFLM_00285	COG3210	domain, Protein
XFLM_00330	COG0277	FAD linked oxidase domain protein
XFLM_00335	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
XFLM_00340	COG0531	amino acid
XFLM_00345	COG0531	amino acid
XFLM_00425	COG0460	homoserine dehydrogenase
XFLM_00425	COG0527	aspartate kinase activity
XFLM_00445	COG1686	Belongs to the peptidase S11 family
XFLM_00480	COG4953	penicillin-binding protein 1C
XFLM_00510	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XFLM_00585	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XFLM_00590	COG0823	Involved in the tonB-independent uptake of proteins
XFLM_00590	COG1506	peptidase
XFLM_00595	COG1297	OPT oligopeptide transporter protein
XFLM_00625	COG0676	glucose-6-phosphate 1-epimerase activity
XFLM_00640	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
XFLM_00645	COG1335	isochorismatase
XFLM_00650	COG0318	PFAM AMP-dependent synthetase and ligase
XFLM_00660	COG0463	Glycosyl transferase, family 2
XFLM_00675	COG1192	Involved in chromosome partitioning
XFLM_00715	COG3772	lysozyme
XFLM_00735	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
XFLM_00770	COG3316	Transposase and inactivated derivatives
XFLM_00785	COG0489	protein tyrosine kinase activity
XFLM_00795	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
XFLM_00905	COG1605	Chorismate mutase
XFLM_00905	COG0077	Prephenate dehydratase
XFLM_00920	COG1668	transmembrane transport
XFLM_00925	COG4555	ABC transporter
XFLM_00950	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
XFLM_00965	COG1605	Chorismate mutase
XFLM_00965	COG0287	Prephenate dehydrogenase
XFLM_01005	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XFLM_01030	COG1278	Cold shock
XFLM_01070	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
XFLM_01095	COG0438	transferase activity, transferring glycosyl groups
XFLM_01165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XFLM_01170	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XFLM_01185	COG1064	alcohol dehydrogenase
XFLM_01210	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
XFLM_01220	COG0436	Aminotransferase
XFLM_01315	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
XFLM_01315	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XFLM_01380	COG0196	riboflavin kinase activity
XFLM_01385	COG0728	peptidoglycan biosynthetic process
XFLM_01390	COG0268	Binds directly to 16S ribosomal RNA
XFLM_01440	COG1210	Utp--glucose-1-phosphate uridylyltransferase
XFLM_01455	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
XFLM_01520	COG1175	transmembrane transport
XFLM_01545	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
XFLM_01555	COG1187	pseudouridine synthase activity
XFLM_01570	COG0436	Aminotransferase
XFLM_01630	COG5434	Belongs to the glycosyl hydrolase 28 family
XFLM_01650	COG0402	S-adenosylhomocysteine deaminase activity
XFLM_01660	COG1509	lysine 2,3-aminomutase activity
XFLM_01695	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
XFLM_01700	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
XFLM_01715	COG1028	Short-chain dehydrogenase reductase Sdr
XFLM_01760	COG0142	geranyltranstransferase activity
XFLM_01785	COG1301	dicarboxylic acid transport
XFLM_01795	COG0791	NLP P60 protein
XFLM_01800	COG0791	NLP P60 protein
XFLM_01810	COG2311	Membrane
XFLM_01830	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
XFLM_01885	COG0351	phosphomethylpyrimidine kinase
XFLM_01885	COG0352	thiamine-phosphate diphosphorylase activity
XFLM_01895	COG1324	tolerance protein
XFLM_01930	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XFLM_01935	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XFLM_01940	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
XFLM_01955	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
XFLM_01975	COG4774	siderophore transport
XFLM_02005	COG1477	protein flavinylation
XFLM_02010	COG1555	photosystem II stabilization
XFLM_02015	COG3178	'Phosphotransferase
XFLM_02020	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
XFLM_02030	COG0628	permease
XFLM_02045	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
XFLM_02070	COG3590	peptidase
XFLM_02140	COG0519	Catalyzes the synthesis of GMP from XMP
XFLM_02140	COG0518	GMP synthase (glutamine-hydrolyzing) activity
XFLM_02155	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
XFLM_02170	COG3107	peptidoglycan biosynthetic process
XFLM_02195	COG2878	Part of a membrane complex involved in electron transport
XFLM_02255	COG0358	DNA primase activity
XFLM_02265	COG0629	single-stranded DNA binding
XFLM_02300	COG0827	DNA restriction-modification system
XFLM_02305	COG0827	DNA restriction-modification system
XFLM_02340	COG4968	Prepilin-type N-terminal cleavage methylation domain
XFLM_02345	COG1611	Belongs to the LOG family
XFLM_02350	COG4943	cyclic-guanylate-specific phosphodiesterase activity
XFLM_02355	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
XFLM_02370	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XFLM_02400	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
XFLM_02415	COG0330	HflC and HflK could
XFLM_02420	COG0330	HflC and HflK could
XFLM_02425	COG0604	alcohol dehydrogenase
XFLM_02455	COG1183	phosphatidylcholine synthase activity
XFLM_02475	COG0668	transmembrane transport
XFLM_02480	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
XFLM_02500	COG1610	YqeY-like protein
XFLM_02510	COG0358	DNA primase activity
XFLM_02550	COG1074	ATP-dependent DNA helicase activity
XFLM_02555	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
XFLM_02560	COG1127	ABC transporter
XFLM_02565	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
XFLM_02590	COG2853	Lipoprotein
XFLM_02605	COG1116	anion transmembrane transporter activity
XFLM_02625	COG0531	amino acid
XFLM_02630	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
XFLM_02635	COG0861	Integral membrane protein TerC family
XFLM_02660	COG2193	ferroxidase activity
XFLM_02680	COG2205	protein histidine kinase activity
XFLM_02685	COG0745	RESPONSE REGULATOR receiver
XFLM_02735	COG2194	sulfuric ester hydrolase activity
XFLM_02775	COG0667	Aldo Keto reductase
XFLM_02780	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XFLM_02790	COG0305	Participates in initiation and elongation during chromosome replication
XFLM_02810	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
XFLM_02820	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
XFLM_02830	COG0277	FAD linked oxidase domain protein
XFLM_02860	COG4206	TonB-dependent receptor
XFLM_02885	COG4197	protein conserved in bacteria, prophage-related
XFLM_02965	COG3617	BRO family, N-terminal domain
XFLM_03055	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
XFLM_03070	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
XFLM_03095	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
XFLM_03095	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
XFLM_03120	COG0488	(ABC) transporter
XFLM_03130	COG3011	Protein conserved in bacteria
XFLM_03160	COG1918	ferrous iron import across plasma membrane
XFLM_03160	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
XFLM_03170	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
XFLM_03195	COG0758	DNA mediated transformation
XFLM_03245	COG2969	positive regulation of protein catabolic process
XFLM_03250	COG0625	glutathione transferase activity
XFLM_03255	COG2857	Cytochrome c1
XFLM_03270	COG0723	plastoquinol--plastocyanin reductase activity
XFLM_03275	COG0741	lytic transglycosylase activity
XFLM_03285	COG1702	phosphate starvation-inducible protein PhoH
XFLM_03300	COG4535	Mg2 and Co2 transporter CorC
XFLM_03320	COG0598	Magnesium transport protein CorA
XFLM_03395	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
XFLM_03425	COG0288	reversible hydration of carbon dioxide
XFLM_03450	COG2011	ABC-type metal ion transport system permease component
XFLM_03465	COG0508	dehydrogenase complex catalyzes the overall conversion of
XFLM_03505	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XFLM_03510	COG0739	heme binding
XFLM_03530	COG1238	metal cluster binding
XFLM_03545	COG5002	protein histidine kinase activity
XFLM_03570	COG1388	LysM domain
XFLM_03570	COG3858	chitin binding
XFLM_03575	COG3525	Glycosyl hydrolase, family 20, catalytic domain
XFLM_03610	COG3537	Alpha-1,2-mannosidase
XFLM_03640	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XFLM_03645	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XFLM_03685	COG0469	pyruvate kinase activity
XFLM_03705	COG0735	belongs to the Fur family
XFLM_03715	COG5297	Belongs to the glycosyl hydrolase family 6
XFLM_03715	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XFLM_03740	COG4305	rare lipoprotein A
XFLM_03750	COG0739	heme binding
XFLM_03765	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
XFLM_03775	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
XFLM_03810	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
XFLM_03825	COG3116	cell division
XFLM_03900	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
XFLM_03960	COG0860	N-Acetylmuramoyl-L-alanine amidase
XFLM_03965	COG0802	atpase or kinase
XFLM_03970	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
XFLM_03970	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
XFLM_04075	COG0745	RESPONSE REGULATOR receiver
XFLM_04080	COG0642	Histidine kinase
XFLM_04090	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
XFLM_04140	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
XFLM_04150	COG2831	hemolysin activation secretion protein
XFLM_04185	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
XFLM_04230	COG0316	Belongs to the HesB IscA family
XFLM_04270	COG0697	spore germination
XFLM_04275	COG0671	phosphoesterase, PA-phosphatase related
XFLM_04290	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
XFLM_04305	COG1132	(ABC) transporter
XFLM_04315	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
XFLM_04320	COG1538	Outer membrane efflux protein
XFLM_04345	COG0745	RESPONSE REGULATOR receiver
XFLM_04350	COG4783	chaperone-mediated protein folding
XFLM_04360	COG0473	3-isopropylmalate dehydrogenase activity
XFLM_04375	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
XFLM_04380	COG3083	sulfuric ester hydrolase activity
XFLM_04385	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
XFLM_04410	COG0564	pseudouridine synthase activity
XFLM_04420	COG1530	ribonuclease E activity
XFLM_04425	COG2197	response regulator
XFLM_04470	COG1278	Cold shock
XFLM_04500	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
XFLM_04655	COG2095	MarC family integral membrane protein
XFLM_04660	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
XFLM_04690	COG2132	Multicopper oxidase
XFLM_04700	COG0210	DNA helicase
XFLM_04710	COG0616	signal peptide processing
XFLM_04735	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
XFLM_04760	COG2177	Part of the ABC transporter FtsEX involved in
XFLM_04765	COG2884	Cell division ATP-binding protein ftsE
XFLM_04775	COG3118	belongs to the thioredoxin family
XFLM_04780	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
XFLM_04795	COG0793	Belongs to the peptidase S41A family
XFLM_04820	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XFLM_04825	COG0493	'glutamate synthase
XFLM_04830	COG0070	glutamate synthase
XFLM_04830	COG0069	glutamate synthase activity
XFLM_04830	COG0067	glutamate synthase
XFLM_04885	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
XFLM_04945	COG4942	peptidase
XFLM_05070	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
XFLM_05075	COG3657	addiction module killer protein
XFLM_05225	COG0592	DNA-directed DNA polymerase activity
XFLM_05240	COG0187	DNA topoisomerase II activity
XFLM_05255	COG0501	Belongs to the peptidase M48B family
XFLM_05290	COG0823	Involved in the tonB-independent uptake of proteins
XFLM_05290	COG1506	peptidase
XFLM_05290	COG4946	Tricorn protease homolog
XFLM_05320	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
XFLM_05390	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
XFLM_05420	COG0511	ligase activity, forming carbon-carbon bonds
XFLM_05425	COG0439	Biotin carboxylase
XFLM_05430	COG0210	DNA helicase
XFLM_05470	COG1040	competence protein
XFLM_05480	COG1752	Esterase of the alpha-beta hydrolase superfamily
XFLM_05505	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
XFLM_05520	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
XFLM_05560	COG3121	Chaperone
XFLM_05565	COG3539	Fimbrial protein
XFLM_05575	COG1546	Belongs to the CinA family
XFLM_05580	COG0477	Major facilitator Superfamily
XFLM_05585	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
XFLM_05600	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
XFLM_05610	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
XFLM_05620	COG1534	Rna-binding protein
XFLM_05650	COG1560	Kdo2-lipid A biosynthetic process
XFLM_05655	COG1519	Transferase
XFLM_05685	COG0024	Methionine aminopeptidase
XFLM_05700	COG1393	Belongs to the ArsC family
XFLM_05715	COG0367	asparagine synthase
XFLM_05725	COG2070	2-Nitropropane dioxygenase
XFLM_05755	COG0339	signal peptide processing
XFLM_05770	COG2132	Multicopper oxidase
XFLM_05805	COG0795	lipopolysaccharide-transporting ATPase activity
XFLM_05845	COG4221	oxidoreductase activity
XFLM_05870	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
XFLM_05885	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
XFLM_05940	COG2223	nitrite transmembrane transporter activity
XFLM_05950	COG0739	heme binding
XFLM_05965	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
XFLM_05985	COG1028	Short-chain dehydrogenase reductase Sdr
XFLM_05995	COG1272	protein, Hemolysin III
XFLM_06000	COG0463	Glycosyl transferase, family 2
XFLM_06005	COG0084	hydrolase, TatD family'
XFLM_06045	COG0330	HflC and HflK could
XFLM_06050	COG3956	TIGRFAM MazG family protein
XFLM_06055	COG1218	3'(2'),5'-bisphosphate nucleotidase
XFLM_06060	COG0494	nUDIX hydrolase
XFLM_06070	COG1385	rRNA (uridine-N3-)-methyltransferase activity
XFLM_06075	COG0513	Belongs to the DEAD box helicase family
XFLM_06080	COG0720	synthase
XFLM_06145	COG0512	Glutamine amidotransferase of anthranilate synthase
XFLM_06175	COG0006	proline dipeptidase activity
XFLM_06195	COG1862	Preprotein translocase
XFLM_06200	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
XFLM_06205	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
XFLM_06210	COG0617	tRNA 3'-terminal CCA addition
XFLM_06245	COG0195	Participates in both transcription termination and antitermination
XFLM_06275	COG1733	regulation of RNA biosynthetic process
XFLM_06280	COG0702	epimerase
XFLM_06335	COG2086	electron transfer activity
XFLM_06365	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
XFLM_06405	COG0477	Major facilitator Superfamily
XFLM_06430	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
XFLM_06435	COG0671	phosphoesterase, PA-phosphatase related
XFLM_06450	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
XFLM_06455	COG0628	permease
XFLM_06475	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XFLM_06480	COG1090	epimerase
XFLM_06485	COG0318	PFAM AMP-dependent synthetase and ligase
XFLM_06510	COG1049	propionate catabolic process, 2-methylcitrate cycle
XFLM_06565	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XFLM_06590	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XFLM_06610	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
XFLM_06615	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
XFLM_06620	COG1034	ATP synthesis coupled electron transport
XFLM_06635	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XFLM_06660	COG1007	ATP synthesis coupled electron transport
XFLM_06665	COG1028	Short-chain dehydrogenase reductase Sdr
XFLM_06670	COG2851	Citrate transporter
XFLM_06690	COG0642	Histidine kinase
XFLM_06710	COG0784	Response regulator, receiver
XFLM_06710	COG2205	protein histidine kinase activity
XFLM_06725	COG0280	phosphate acetyltransferase
XFLM_06725	COG0281	malic enzyme
XFLM_06735	COG0742	ribosomal rna small subunit methyltransferase
XFLM_06750	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
XFLM_06765	COG3706	GGDEF domain
XFLM_06775	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
XFLM_06785	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
XFLM_06805	COG2166	iron-sulfur cluster assembly
XFLM_06835	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XFLM_06910	COG0590	tRNA wobble adenosine to inosine editing
XFLM_06915	COG1321	iron dependent repressor
XFLM_06945	COG1946	Acyl-CoA thioesterase
XFLM_07040	COG0575	Belongs to the CDS family
XFLM_07115	COG0354	folic acid binding
XFLM_07125	COG2009	succinate dehydrogenase
XFLM_07130	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
XFLM_07140	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
XFLM_07170	COG0811	peptide transport
XFLM_07230	COG3093	addiction module antidote protein HigA
XFLM_07240	COG2944	sequence-specific DNA binding
XFLM_07305	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
XFLM_07325	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XFLM_07405	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
XFLM_07410	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
XFLM_07430	COG1024	Enoyl-CoA hydratase
XFLM_07435	COG0019	diaminopimelate decarboxylase activity
XFLM_07450	COG0494	nUDIX hydrolase
XFLM_07475	COG1530	ribonuclease E activity
XFLM_07490	COG0312	modulator of DNA gyrase
XFLM_07500	COG0312	modulator of DNA gyrase
XFLM_07505	COG0583	DNA-binding transcription factor activity
XFLM_07520	COG1064	alcohol dehydrogenase
XFLM_07580	COG0356	it plays a direct role in the translocation of protons across the membrane
XFLM_07700	COG0201	protein transport
XFLM_07730	COG2960	long-chain fatty acid transporting porin activity
XFLM_07735	COG0606	chelatase, subunit chli
XFLM_07810	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
XFLM_07815	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
XFLM_07830	COG1187	pseudouridine synthase activity
XFLM_07835	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
XFLM_07855	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XFLM_07865	COG0625	glutathione transferase activity
XFLM_07875	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
XFLM_07915	COG0842	Transport permease protein
XFLM_07920	COG1131	(ABC) transporter
XFLM_07940	COG1643	Atp-dependent helicase
XFLM_07945	COG1956	GAF domain-containing protein
XFLM_07950	COG0729	surface antigen
XFLM_07955	COG2911	Protein conserved in bacteria
XFLM_08005	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
XFLM_08070	COG0668	transmembrane transport
XFLM_08145	COG2733	membrane
XFLM_08150	COG1253	flavin adenine dinucleotide binding
XFLM_08225	COG0644	oxidoreductase
XFLM_08225	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
XFLM_08240	COG3218	ABC-type transport auxiliary lipoprotein component
XFLM_08240	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
XFLM_08245	COG1127	ABC transporter
XFLM_08250	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
XFLM_08275	COG1077	Cell shape determining protein MreB Mrl
XFLM_08280	COG1792	Involved in formation and maintenance of cell shape
XFLM_08285	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
XFLM_08290	COG0768	penicillin binding
XFLM_08295	COG0772	Belongs to the SEDS family
XFLM_08305	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
XFLM_08325	COG2894	cell division
XFLM_08355	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
XFLM_08370	COG2353	YceI-like domain
XFLM_08450	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
XFLM_08455	COG4208	sulfate ABC transporter
XFLM_08490	COG1846	Transcriptional regulator
XFLM_08535	COG0741	lytic transglycosylase activity
XFLM_08550	COG1999	signal sequence binding
XFLM_08580	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
XFLM_08620	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XFLM_08630	COG0514	ATP-dependent DNA helicase (RecQ)
XFLM_08635	COG0783	Belongs to the Dps family
XFLM_08640	COG1643	Atp-dependent helicase
XFLM_08650	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
XFLM_08655	COG1845	cytochrome c oxidase, subunit III
XFLM_08660	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
XFLM_08665	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
XFLM_08670	COG0142	geranyltranstransferase activity
XFLM_08685	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
XFLM_08715	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
XFLM_08750	COG1137	ATPase activity
XFLM_08765	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
XFLM_08775	COG0271	Belongs to the BolA IbaG family
XFLM_08815	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
XFLM_08825	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XFLM_08875	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
XFLM_08905	COG0542	response to heat
XFLM_08925	COG0492	ferredoxin-NADP+ reductase activity
XFLM_08945	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
XFLM_08960	COG4191	Histidine kinase
XFLM_08965	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
XFLM_08970	COG1028	Short-chain dehydrogenase reductase Sdr
XFLM_09000	COG1609	Transcriptional regulator
XFLM_09005	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
XFLM_09010	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
XFLM_09015	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
XFLM_09025	COG0726	polysaccharide deacetylase
XFLM_09030	COG0297	glycogen (starch) synthase activity
XFLM_09050	COG0719	Fe-S assembly protein
XFLM_09055	COG0396	ATPase activity
XFLM_09060	COG0719	Fe-S assembly protein
XFLM_09065	COG1959	2 iron, 2 sulfur cluster binding
XFLM_09120	COG0308	aminopeptidase N
XFLM_09175	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
XFLM_09200	COG1561	YicC-like family, N-terminal region
XFLM_09215	COG0635	Involved in the biosynthesis of porphyrin-containing compound
XFLM_09250	COG5295	Hep Hag repeat protein
XFLM_09255	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
XFLM_09260	COG1459	type II secretion system
XFLM_09270	COG2165	general secretion pathway protein
XFLM_09275	COG4970	Tfp pilus assembly protein FimT
XFLM_09280	COG2165	general secretion pathway protein
XFLM_09285	COG4795	General secretion pathway protein
XFLM_09290	COG3156	type II secretion system protein K
XFLM_09295	COG3166	PFAM Fimbrial assembly family protein
XFLM_09310	COG1450	Type ii and iii secretion system protein
XFLM_09320	COG0450	alkyl hydroperoxide reductase
XFLM_09325	COG3634	alkyl hydroperoxide reductase activity
XFLM_09330	COG0583	DNA-binding transcription factor activity
XFLM_09390	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
XFLM_09420	COG0567	Dehydrogenase, E1 component
XFLM_09425	COG2850	peptidyl-arginine hydroxylation
XFLM_09440	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
XFLM_09530	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
XFLM_09535	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XFLM_09540	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XFLM_09595	COG2925	Exonuclease
XFLM_09605	COG0025	NhaP-type Na H and K H
XFLM_09625	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
XFLM_09645	COG0006	proline dipeptidase activity
XFLM_09655	COG0778	Nitroreductase
XFLM_09695	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
XFLM_09740	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XFLM_09750	COG0557	exoribonuclease II activity
XFLM_09760	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
XFLM_09790	COG1289	transmembrane transporter activity
XFLM_09830	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
XFLM_09840	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XFLM_09860	COG0596	Alpha beta hydrolase
XFLM_09920	COG0840	transmembrane signaling receptor activity
XFLM_09955	COG0285	dihydrofolate synthase activity
XFLM_09965	COG0339	signal peptide processing
XFLM_09995	COG1301	dicarboxylic acid transport
XFLM_10000	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
XFLM_10010	COG2091	lysine biosynthetic process via aminoadipic acid
XFLM_10070	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
XFLM_10095	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
XFLM_10095	COG0512	Glutamine amidotransferase of anthranilate synthase
XFLM_10115	COG0084	hydrolase, TatD family'
XFLM_10135	COG0552	protein localization to endoplasmic reticulum
XFLM_10175	COG0824	Thioesterase
XFLM_10200	COG2885	chlorophyll binding
XFLM_10210	COG0602	queuosine metabolic process
XFLM_10225	COG3104	oligopeptide transport
XFLM_10230	COG0386	Belongs to the glutathione peroxidase family
XFLM_10250	COG0406	alpha-ribazole phosphatase activity
XFLM_10350	COG0675	Transposase, IS605 OrfB family
XFLM_10535	COG2369	cell adhesion
XFLM_10620	COG0582	viral genome integration into host DNA
XFLM_10625	COG3567	Phage-associated protein, HI1409 family
XFLM_10630	COG5410	chromosome segregation
XFLM_10655	COG3772	lysozyme
XFLM_10695	COG3617	BRO family, N-terminal domain
XFLM_10780	COG5532	Uncharacterized conserved protein (DUF2303)
XFLM_10805	COG0629	single-stranded DNA binding
XFLM_10815	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
XFLM_10820	COG3852	Histidine kinase
XFLM_10825	COG2204	response regulator
XFLM_10840	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
XFLM_10845	COG0004	ammonium transporteR
XFLM_10850	COG0347	Belongs to the P(II) protein family
XFLM_10855	COG0174	glutamine synthetase
XFLM_10870	COG2353	YceI-like domain
XFLM_10950	COG1764	response to oxidative stress
XFLM_10955	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XFLM_11000	COG1399	metal-binding, possibly nucleic acid-binding protein
XFLM_11015	COG0714	Associated with various cellular activities
XFLM_11035	COG0537	adenosine 5'-monophosphoramidase activity
XFLM_11050	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
XFLM_11100	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
XFLM_11125	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
XFLM_11125	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
XFLM_11175	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
XFLM_11205	COG0251	oxidation-reduction process
XFLM_11270	COG3077	Addiction module antitoxin, RelB DinJ family
XFLM_11275	COG3041	Addiction module toxin RelE StbE family
XFLM_11350	COG3772	lysozyme
XFLM_11450	COG3617	BRO family, N-terminal domain
XFLM_11485	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
XFLM_11490	COG0392	lysyltransferase activity
XFLM_11490	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
XFLM_11500	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
XFLM_11510	COG0463	Glycosyl transferase, family 2
XFLM_11560	COG3275	phosphorelay sensor kinase activity
XFLM_11565	COG0400	carboxylic ester hydrolase activity
XFLM_11590	COG2226	methyltransferase
XFLM_11625	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XFLM_11660	COG0386	Belongs to the glutathione peroxidase family
XFLM_11665	COG1131	(ABC) transporter
XFLM_11695	COG3657	addiction module killer protein
XFLM_11700	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
XFLM_11765	COG0675	Transposase, IS605 OrfB family
XFLM_11940	COG3736	Type IV secretory pathway, component VirB8