locus-tag	class	description
D1605_000010	COG0592	DNA-directed DNA polymerase activity
D1605_000020	COG0187	DNA topoisomerase II activity
D1605_000030	COG0501	Belongs to the peptidase M48B family
D1605_000060	COG4946	Tricorn protease homolog
D1605_000060	COG1506	peptidase
D1605_000060	COG0823	Involved in the tonB-independent uptake of proteins
D1605_000090	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
D1605_000155	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
D1605_000165	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
D1605_000175	COG0511	ligase activity, forming carbon-carbon bonds
D1605_000180	COG0439	Biotin carboxylase
D1605_000185	COG0210	DNA helicase
D1605_000210	COG1040	competence protein
D1605_000220	COG1752	Esterase of the alpha-beta hydrolase superfamily
D1605_000260	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
D1605_000270	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
D1605_000300	COG3121	Chaperone
D1605_000305	COG3539	Fimbrial protein
D1605_000310	COG1546	Belongs to the CinA family
D1605_000315	COG0477	Major facilitator Superfamily
D1605_000320	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
D1605_000335	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
D1605_000345	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
D1605_000355	COG1534	Rna-binding protein
D1605_000385	COG1560	Kdo2-lipid A biosynthetic process
D1605_000390	COG1519	Transferase
D1605_000430	COG1393	Belongs to the ArsC family
D1605_000440	COG0367	asparagine synthase
D1605_000450	COG2070	2-Nitropropane dioxygenase
D1605_000480	COG0339	signal peptide processing
D1605_000495	COG2132	Multicopper oxidase
D1605_000530	COG0795	lipopolysaccharide-transporting ATPase activity
D1605_000565	COG4221	oxidoreductase activity
D1605_000585	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
D1605_000605	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
D1605_000660	COG2223	nitrite transmembrane transporter activity
D1605_000670	COG0739	heme binding
D1605_000705	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
D1605_000720	COG1028	Short-chain dehydrogenase reductase Sdr
D1605_000730	COG1272	protein, Hemolysin III
D1605_000735	COG0463	Glycosyl transferase, family 2
D1605_000740	COG0084	hydrolase, TatD family'
D1605_000770	COG0330	HflC and HflK could
D1605_000775	COG3956	TIGRFAM MazG family protein
D1605_000780	COG1218	3'(2'),5'-bisphosphate nucleotidase
D1605_000785	COG0494	nUDIX hydrolase
D1605_000795	COG1385	rRNA (uridine-N3-)-methyltransferase activity
D1605_000800	COG0513	Belongs to the DEAD box helicase family
D1605_000805	COG0720	synthase
D1605_000830	COG1981	membrane
D1605_000865	COG0512	Glutamine amidotransferase of anthranilate synthase
D1605_000900	COG0006	proline dipeptidase activity
D1605_000920	COG1862	Preprotein translocase
D1605_000925	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
D1605_000930	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
D1605_000940	COG0617	tRNA 3'-terminal CCA addition
D1605_000980	COG0195	Participates in both transcription termination and antitermination
D1605_001010	COG1733	regulation of RNA biosynthetic process
D1605_001015	COG0702	epimerase
D1605_001065	COG2086	electron transfer activity
D1605_001095	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
D1605_001130	COG0477	Major facilitator Superfamily
D1605_001150	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
D1605_001155	COG0671	phosphoesterase, PA-phosphatase related
D1605_001165	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
D1605_001170	COG0628	permease
D1605_001190	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D1605_001195	COG1090	epimerase
D1605_001200	COG0318	PFAM AMP-dependent synthetase and ligase
D1605_001220	COG1049	propionate catabolic process, 2-methylcitrate cycle
D1605_001265	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D1605_001290	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
D1605_001310	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
D1605_001315	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
D1605_001320	COG1034	ATP synthesis coupled electron transport
D1605_001355	COG1007	ATP synthesis coupled electron transport
D1605_001360	COG1028	Short-chain dehydrogenase reductase Sdr
D1605_001365	COG2851	Citrate transporter
D1605_001380	COG0642	Histidine kinase
D1605_001400	COG0784	Response regulator, receiver
D1605_001400	COG2205	protein histidine kinase activity
D1605_001420	COG0280	phosphate acetyltransferase
D1605_001420	COG0281	malic enzyme
D1605_001430	COG0742	ribosomal rna small subunit methyltransferase
D1605_001450	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
D1605_001470	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
D1605_001495	COG2166	iron-sulfur cluster assembly
D1605_001525	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D1605_001600	COG1321	iron dependent repressor
D1605_001620	COG1946	Acyl-CoA thioesterase
D1605_001720	COG0575	Belongs to the CDS family
D1605_001820	COG0354	folic acid binding
D1605_001830	COG2009	succinate dehydrogenase
D1605_001835	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
D1605_001845	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
D1605_001875	COG0811	peptide transport
D1605_001925	COG3093	addiction module antidote protein HigA
D1605_001935	COG2944	sequence-specific DNA binding
D1605_002000	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
D1605_002020	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D1605_002090	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
D1605_002115	COG1024	Enoyl-CoA hydratase
D1605_002120	COG0019	diaminopimelate decarboxylase activity
D1605_002140	COG0494	nUDIX hydrolase
D1605_002145	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
D1605_002170	COG0312	modulator of DNA gyrase
D1605_002180	COG0312	modulator of DNA gyrase
D1605_002185	COG0583	DNA-binding transcription factor activity
D1605_002200	COG1064	alcohol dehydrogenase
D1605_002255	COG0356	it plays a direct role in the translocation of protons across the membrane
D1605_002375	COG0201	protein transport
D1605_002405	COG2960	long-chain fatty acid transporting porin activity
D1605_002410	COG0606	chelatase, subunit chli
D1605_002435	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
D1605_002495	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
D1605_002500	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
D1605_002515	COG1187	pseudouridine synthase activity
D1605_002520	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
D1605_002545	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D1605_002550	COG0625	glutathione transferase activity
D1605_002560	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
D1605_002565	COG1217	gtp-binding protein TYPA
D1605_002605	COG0842	Transport permease protein
D1605_002610	COG1131	(ABC) transporter
D1605_002635	COG1643	Atp-dependent helicase
D1605_002645	COG1956	GAF domain-containing protein
D1605_002650	COG0729	surface antigen
D1605_002655	COG2911	Protein conserved in bacteria
D1605_002665	COG0582	viral genome integration into host DNA
D1605_002850	COG0668	transmembrane transport
D1605_002880	COG5297	Belongs to the glycosyl hydrolase family 6
D1605_002915	COG2733	membrane
D1605_002920	COG1253	flavin adenine dinucleotide binding
D1605_002985	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
D1605_002985	COG0644	oxidoreductase
D1605_003000	COG3218	ABC-type transport auxiliary lipoprotein component
D1605_003000	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
D1605_003005	COG1127	ABC transporter
D1605_003010	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
D1605_003045	COG1077	Cell shape determining protein MreB Mrl
D1605_003050	COG1792	Involved in formation and maintenance of cell shape
D1605_003055	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
D1605_003060	COG0768	penicillin binding
D1605_003065	COG0772	Belongs to the SEDS family
D1605_003075	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
D1605_003095	COG2894	cell division
D1605_003115	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
D1605_003130	COG2353	YceI-like domain
D1605_003200	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
D1605_003205	COG4208	sulfate ABC transporter
D1605_003230	COG1846	Transcriptional regulator
D1605_003270	COG0741	lytic transglycosylase activity
D1605_003280	COG1999	signal sequence binding
D1605_003300	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
D1605_003335	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D1605_003345	COG0514	ATP-dependent DNA helicase (RecQ)
D1605_003350	COG0783	Belongs to the Dps family
D1605_003355	COG1643	Atp-dependent helicase
D1605_003365	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
D1605_003370	COG1845	cytochrome c oxidase, subunit III
D1605_003375	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
D1605_003380	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
D1605_003385	COG0142	geranyltranstransferase activity
D1605_003400	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
D1605_003420	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
D1605_003455	COG1137	ATPase activity
D1605_003470	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
D1605_003480	COG0271	Belongs to the BolA IbaG family
D1605_003520	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
D1605_003530	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D1605_003565	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
D1605_003595	COG0542	response to heat
D1605_003615	COG0492	ferredoxin-NADP+ reductase activity
D1605_003635	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
D1605_003650	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
D1605_003655	COG1028	Short-chain dehydrogenase reductase Sdr
D1605_003685	COG1609	Transcriptional regulator
D1605_003690	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
D1605_003695	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
D1605_003700	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
D1605_003710	COG0726	polysaccharide deacetylase
D1605_003715	COG0297	glycogen (starch) synthase activity
D1605_003735	COG0719	Fe-S assembly protein
D1605_003740	COG0396	ATPase activity
D1605_003745	COG0719	Fe-S assembly protein
D1605_003750	COG1959	2 iron, 2 sulfur cluster binding
D1605_003805	COG0308	aminopeptidase N
D1605_003855	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
D1605_003880	COG1561	YicC-like family, N-terminal region
D1605_003895	COG0635	Involved in the biosynthesis of porphyrin-containing compound
D1605_003930	COG5295	Hep Hag repeat protein
D1605_003935	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
D1605_003940	COG1459	type II secretion system
D1605_003950	COG2165	general secretion pathway protein
D1605_003955	COG4970	Tfp pilus assembly protein FimT
D1605_003960	COG2165	general secretion pathway protein
D1605_003965	COG4795	General secretion pathway protein
D1605_003970	COG3156	type II secretion system protein K
D1605_003975	COG3166	PFAM Fimbrial assembly family protein
D1605_003990	COG1450	Type ii and iii secretion system protein
D1605_004005	COG3634	alkyl hydroperoxide reductase activity
D1605_004010	COG0583	DNA-binding transcription factor activity
D1605_004075	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
D1605_004100	COG0567	Dehydrogenase, E1 component
D1605_004105	COG2850	peptidyl-arginine hydroxylation
D1605_004120	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
D1605_004230	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D1605_004235	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D1605_004240	COG2902	Dehydrogenase
D1605_004280	COG2925	Exonuclease
D1605_004290	COG0025	NhaP-type Na H and K H
D1605_004310	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
D1605_004335	COG0006	proline dipeptidase activity
D1605_004345	COG0778	Nitroreductase
D1605_004375	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
D1605_004415	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D1605_004425	COG0557	exoribonuclease II activity
D1605_004435	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
D1605_004450	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
D1605_004455	COG1289	transmembrane transporter activity
D1605_004475	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
D1605_004485	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
D1605_004505	COG0596	Alpha beta hydrolase
D1605_004510	COG0727	PFAM Uncharacterised protein family (UPF0153)
D1605_004555	COG0840	transmembrane signaling receptor activity
D1605_004560	COG0643	Histidine kinase
D1605_004560	COG2198	Histidine kinase
D1605_004560	COG0784	Response regulator, receiver
D1605_004590	COG0285	dihydrofolate synthase activity
D1605_004600	COG0339	signal peptide processing
D1605_004620	COG1301	dicarboxylic acid transport
D1605_004625	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
D1605_004635	COG2091	lysine biosynthetic process via aminoadipic acid
D1605_004680	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
D1605_004710	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
D1605_004710	COG0512	Glutamine amidotransferase of anthranilate synthase
D1605_004730	COG0084	hydrolase, TatD family'
D1605_004750	COG0552	protein localization to endoplasmic reticulum
D1605_004795	COG0824	Thioesterase
D1605_004820	COG2885	chlorophyll binding
D1605_004830	COG0602	queuosine metabolic process
D1605_004850	COG0386	Belongs to the glutathione peroxidase family
D1605_004870	COG0406	alpha-ribazole phosphatase activity
D1605_005115	COG0675	Transposase, IS605 OrfB family
D1605_005275	COG2369	cell adhesion
D1605_005310	COG3210	domain, Protein
D1605_005325	COG0582	viral genome integration into host DNA
D1605_005330	COG3567	Phage-associated protein, HI1409 family
D1605_005335	COG5410	chromosome segregation
D1605_005360	COG3772	lysozyme
D1605_005395	COG3617	BRO family, N-terminal domain
D1605_005475	COG5532	Uncharacterized conserved protein (DUF2303)
D1605_005505	COG0629	single-stranded DNA binding
D1605_005515	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
D1605_005520	COG3852	Histidine kinase
D1605_005525	COG2204	response regulator
D1605_005540	COG0004	ammonium transporteR
D1605_005545	COG0347	Belongs to the P(II) protein family
D1605_005550	COG0174	glutamine synthetase
D1605_005560	COG2353	YceI-like domain
D1605_005615	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
D1605_005620	COG1764	response to oxidative stress
D1605_005625	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D1605_005670	COG1399	metal-binding, possibly nucleic acid-binding protein
D1605_005680	COG0714	Associated with various cellular activities
D1605_005700	COG0537	adenosine 5'-monophosphoramidase activity
D1605_005715	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
D1605_005750	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D1605_005775	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
D1605_005775	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
D1605_005820	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
D1605_005835	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
D1605_005850	COG0251	oxidation-reduction process
D1605_005915	COG3077	Addiction module antitoxin, RelB DinJ family
D1605_005920	COG3041	Addiction module toxin RelE StbE family
D1605_005990	COG3772	lysozyme
D1605_006055	COG4197	protein conserved in bacteria, prophage-related
D1605_006125	COG3617	BRO family, N-terminal domain
D1605_006155	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
D1605_006160	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
D1605_006160	COG0392	lysyltransferase activity
D1605_006170	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
D1605_006180	COG0463	Glycosyl transferase, family 2
D1605_006225	COG3275	phosphorelay sensor kinase activity
D1605_006230	COG0400	carboxylic ester hydrolase activity
D1605_006250	COG2226	methyltransferase
D1605_006275	COG2027	D-alanyl-D-alanine carboxypeptidase
D1605_006285	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D1605_006315	COG0386	Belongs to the glutathione peroxidase family
D1605_006320	COG1131	(ABC) transporter
D1605_006350	COG3657	addiction module killer protein
D1605_006355	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
D1605_006450	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
D1605_006455	COG0488	(ABC) transporter
D1605_006465	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
D1605_006475	COG4651	solute:proton antiporter activity
D1605_006475	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
D1605_006540	COG0859	PFAM glycosyl transferase family 9
D1605_006555	COG0631	protein serine/threonine phosphatase activity
D1605_006560	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
D1605_006590	COG2183	response to ionizing radiation
D1605_006605	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
D1605_006610	COG3118	belongs to the thioredoxin family
D1605_006650	COG2951	lytic endotransglycosylase activity
D1605_006655	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
D1605_006710	COG3210	domain, Protein
D1605_006745	COG0277	FAD linked oxidase domain protein
D1605_006750	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
D1605_006755	COG0531	amino acid
D1605_006845	COG0460	homoserine dehydrogenase
D1605_006845	COG0527	aspartate kinase activity
D1605_006865	COG1686	Belongs to the peptidase S11 family
D1605_006890	COG4953	penicillin-binding protein 1C
D1605_006915	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D1605_006980	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
D1605_006985	COG1506	peptidase
D1605_006985	COG0823	Involved in the tonB-independent uptake of proteins
D1605_006990	COG1297	OPT oligopeptide transporter protein
D1605_007020	COG0676	glucose-6-phosphate 1-epimerase activity
D1605_007030	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
D1605_007035	COG1335	isochorismatase
D1605_007040	COG0318	PFAM AMP-dependent synthetase and ligase
D1605_007050	COG0463	Glycosyl transferase, family 2
D1605_007065	COG1192	Involved in chromosome partitioning
D1605_007125	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
D1605_007170	COG0489	protein tyrosine kinase activity
D1605_007180	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
D1605_007285	COG0077	Prephenate dehydratase
D1605_007285	COG1605	Chorismate mutase
D1605_007300	COG1668	transmembrane transport
D1605_007305	COG4555	ABC transporter
D1605_007330	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
D1605_007340	COG0287	Prephenate dehydrogenase
D1605_007340	COG1605	Chorismate mutase
D1605_007375	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
D1605_007400	COG1278	Cold shock
D1605_007410	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
D1605_007420	COG2954	triphosphatase activity
D1605_007435	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
D1605_007440	COG0438	transferase activity, transferring glycosyl groups
D1605_007455	COG0438	transferase activity, transferring glycosyl groups
D1605_007520	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D1605_007525	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D1605_007540	COG1064	alcohol dehydrogenase
D1605_007560	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
D1605_007570	COG0436	Aminotransferase
D1605_007650	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D1605_007650	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
D1605_007700	COG0196	riboflavin kinase activity
D1605_007705	COG0728	peptidoglycan biosynthetic process
D1605_007710	COG0268	Binds directly to 16S ribosomal RNA
D1605_007760	COG1210	Utp--glucose-1-phosphate uridylyltransferase
D1605_007775	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
D1605_007830	COG0395	ABC-type sugar transport system, permease component
D1605_007835	COG1175	transmembrane transport
D1605_007865	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
D1605_007885	COG0436	Aminotransferase
D1605_007945	COG5434	Belongs to the glycosyl hydrolase 28 family
D1605_007970	COG0402	S-adenosylhomocysteine deaminase activity
D1605_007980	COG1509	lysine 2,3-aminomutase activity
D1605_008020	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
D1605_008025	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
D1605_008040	COG1028	Short-chain dehydrogenase reductase Sdr
D1605_008090	COG0142	geranyltranstransferase activity
D1605_008110	COG1301	dicarboxylic acid transport
D1605_008120	COG0791	NLP P60 protein
D1605_008125	COG0791	NLP P60 protein
D1605_008135	COG2311	Membrane
D1605_008145	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
D1605_008205	COG0352	thiamine-phosphate diphosphorylase activity
D1605_008205	COG0351	phosphomethylpyrimidine kinase
D1605_008215	COG1324	tolerance protein
D1605_008250	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D1605_008255	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D1605_008260	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
D1605_008275	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
D1605_008295	COG4774	siderophore transport
D1605_008320	COG1477	protein flavinylation
D1605_008325	COG1555	photosystem II stabilization
D1605_008330	COG3178	'Phosphotransferase
D1605_008335	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
D1605_008345	COG0628	permease
D1605_008365	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
D1605_008385	COG3590	peptidase
D1605_008435	COG0805	protein transport
D1605_008445	COG0518	GMP synthase (glutamine-hydrolyzing) activity
D1605_008445	COG0519	Catalyzes the synthesis of GMP from XMP
D1605_008455	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
D1605_008470	COG3107	peptidoglycan biosynthetic process
D1605_008495	COG2878	Part of a membrane complex involved in electron transport
D1605_008570	COG0629	single-stranded DNA binding
D1605_008595	COG0827	DNA restriction-modification system
D1605_008600	COG0827	DNA restriction-modification system
D1605_008640	COG4968	Prepilin-type N-terminal cleavage methylation domain
D1605_008645	COG1611	Belongs to the LOG family
D1605_008650	COG4943	cyclic-guanylate-specific phosphodiesterase activity
D1605_008655	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
D1605_008665	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
D1605_008695	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
D1605_008710	COG0330	HflC and HflK could
D1605_008715	COG0330	HflC and HflK could
D1605_008720	COG0604	alcohol dehydrogenase
D1605_008750	COG1183	phosphatidylcholine synthase activity
D1605_008770	COG0668	transmembrane transport
D1605_008775	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
D1605_008790	COG1610	YqeY-like protein
D1605_008800	COG0358	DNA primase activity
D1605_008840	COG1074	ATP-dependent DNA helicase activity
D1605_008845	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
D1605_008850	COG1127	ABC transporter
D1605_008855	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
D1605_008875	COG2853	Lipoprotein
D1605_008890	COG1116	anion transmembrane transporter activity
D1605_008900	COG0531	amino acid
D1605_008905	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
D1605_008910	COG0861	Integral membrane protein TerC family
D1605_008945	COG2193	ferroxidase activity
D1605_009035	COG2194	sulfuric ester hydrolase activity
D1605_009075	COG0667	Aldo Keto reductase
D1605_009080	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D1605_009090	COG0305	Participates in initiation and elongation during chromosome replication
D1605_009125	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
D1605_009135	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
D1605_009140	COG0277	FAD linked oxidase domain protein
D1605_009155	COG4206	TonB-dependent receptor
D1605_009260	COG3617	BRO family, N-terminal domain
D1605_009330	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
D1605_009350	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
D1605_009375	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
D1605_009375	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
D1605_009395	COG0488	(ABC) transporter
D1605_009405	COG3011	Protein conserved in bacteria
D1605_009430	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
D1605_009430	COG1918	ferrous iron import across plasma membrane
D1605_009440	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
D1605_009465	COG0758	DNA mediated transformation
D1605_009510	COG2969	positive regulation of protein catabolic process
D1605_009515	COG0625	glutathione transferase activity
D1605_009520	COG2857	Cytochrome c1
D1605_009525	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
D1605_009530	COG0723	plastoquinol--plastocyanin reductase activity
D1605_009535	COG0741	lytic transglycosylase activity
D1605_009545	COG1702	phosphate starvation-inducible protein PhoH
D1605_009560	COG4535	Mg2 and Co2 transporter CorC
D1605_009570	COG0598	Magnesium transport protein CorA
D1605_009605	COG3210	domain, Protein
D1605_009605	COG3210	domain, Protein
D1605_009625	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D1605_009635	COG1199	ATP-dependent helicase activity
D1605_009645	COG0288	reversible hydration of carbon dioxide
D1605_009670	COG2011	ABC-type metal ion transport system permease component
D1605_009690	COG0508	dehydrogenase complex catalyzes the overall conversion of
D1605_009695	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D1605_009710	COG0626	cystathionine gamma-synthase activity
D1605_009715	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
D1605_009720	COG0739	heme binding
D1605_009740	COG1238	metal cluster binding
D1605_009755	COG5002	protein histidine kinase activity
D1605_009775	COG1388	LysM domain
D1605_009775	COG3858	chitin binding
D1605_009780	COG3525	Glycosyl hydrolase, family 20, catalytic domain
D1605_009790	COG1472	Belongs to the glycosyl hydrolase 3 family
D1605_009805	COG3537	Alpha-1,2-mannosidase
D1605_009830	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
D1605_009835	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
D1605_009880	COG0469	pyruvate kinase activity
D1605_009900	COG0735	belongs to the Fur family
D1605_009910	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
D1605_009910	COG5297	Belongs to the glycosyl hydrolase family 6
D1605_009935	COG4305	rare lipoprotein A
D1605_009945	COG0739	heme binding
D1605_009960	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
D1605_009970	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
D1605_010000	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
D1605_010015	COG3116	cell division
D1605_010035	COG0471	metal ion transport
D1605_010035	COG3273	potassium ion transport
D1605_010090	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
D1605_010150	COG0860	N-Acetylmuramoyl-L-alanine amidase
D1605_010155	COG0802	atpase or kinase
D1605_010160	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
D1605_010160	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
D1605_010260	COG0745	RESPONSE REGULATOR receiver
D1605_010265	COG0642	Histidine kinase
D1605_010275	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
D1605_010320	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
D1605_010330	COG2831	hemolysin activation secretion protein
D1605_010355	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
D1605_010395	COG0316	Belongs to the HesB IscA family
D1605_010435	COG0697	spore germination
D1605_010440	COG0671	phosphoesterase, PA-phosphatase related
D1605_010455	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
D1605_010475	COG1132	(ABC) transporter
D1605_010485	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
D1605_010490	COG1538	Outer membrane efflux protein
D1605_010520	COG0745	RESPONSE REGULATOR receiver
D1605_010525	COG4783	chaperone-mediated protein folding
D1605_010535	COG0473	3-isopropylmalate dehydrogenase activity
D1605_010545	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
D1605_010550	COG3083	sulfuric ester hydrolase activity
D1605_010555	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
D1605_010580	COG0564	pseudouridine synthase activity
D1605_010585	COG1530	ribonuclease E activity
D1605_010590	COG2197	response regulator
D1605_010605	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
D1605_010620	COG0488	(ABC) transporter
D1605_010635	COG1278	Cold shock
D1605_010735	COG0012	GTP binding
D1605_010825	COG2095	MarC family integral membrane protein
D1605_010835	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
D1605_010865	COG2132	Multicopper oxidase
D1605_010875	COG0210	DNA helicase
D1605_010885	COG0616	signal peptide processing
D1605_010905	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
D1605_010920	COG2201	protein-glutamate methylesterase activity
D1605_010925	COG2177	Part of the ABC transporter FtsEX involved in
D1605_010930	COG2884	Cell division ATP-binding protein ftsE
D1605_010940	COG3118	belongs to the thioredoxin family
D1605_010945	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
D1605_010960	COG0793	Belongs to the peptidase S41A family
D1605_010965	COG4942	peptidase
D1605_010980	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
D1605_010985	COG0493	'glutamate synthase
D1605_010990	COG0067	glutamate synthase
D1605_010990	COG0070	glutamate synthase
D1605_010990	COG0069	glutamate synthase activity
D1605_011045	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
D1605_011095	COG4942	peptidase
D1605_011240	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
D1605_011245	COG3657	addiction module killer protein
D1605_011325	COG3210	domain, Protein
D1605_011395	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
D1605_011450	COG3451	type IV secretory pathway VirB4
D1605_011465	COG4962	Type ii secretion system protein e
D1605_011475	COG0629	single-stranded DNA binding
D1605_011495	COG0675	Transposase, IS605 OrfB family