locus-tag	class	description
LZ753_00010	COG0592	DNA-directed DNA polymerase activity
LZ753_00020	COG0187	DNA topoisomerase II activity
LZ753_00030	COG0501	Belongs to the peptidase M48B family
LZ753_00060	COG0823	Involved in the tonB-independent uptake of proteins
LZ753_00060	COG1506	peptidase
LZ753_00060	COG4946	Tricorn protease homolog
LZ753_00090	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LZ753_00145	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
LZ753_00155	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LZ753_00165	COG0511	ligase activity, forming carbon-carbon bonds
LZ753_00170	COG0439	Biotin carboxylase
LZ753_00175	COG0210	DNA helicase
LZ753_00205	COG1040	competence protein
LZ753_00215	COG1752	Esterase of the alpha-beta hydrolase superfamily
LZ753_00255	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LZ753_00265	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LZ753_00290	COG3121	Chaperone
LZ753_00295	COG3539	Fimbrial protein
LZ753_00305	COG1546	Belongs to the CinA family
LZ753_00310	COG0477	Major facilitator Superfamily
LZ753_00315	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LZ753_00330	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LZ753_00335	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LZ753_00345	COG1534	Rna-binding protein
LZ753_00375	COG1560	Kdo2-lipid A biosynthetic process
LZ753_00380	COG1519	Transferase
LZ753_00420	COG1393	Belongs to the ArsC family
LZ753_00430	COG0367	asparagine synthase
LZ753_00440	COG2070	2-Nitropropane dioxygenase
LZ753_00470	COG0339	signal peptide processing
LZ753_00485	COG2132	Multicopper oxidase
LZ753_00520	COG0795	lipopolysaccharide-transporting ATPase activity
LZ753_00555	COG4221	oxidoreductase activity
LZ753_00575	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LZ753_00585	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LZ753_00640	COG2223	nitrite transmembrane transporter activity
LZ753_00650	COG0739	heme binding
LZ753_00685	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LZ753_00700	COG1028	Short-chain dehydrogenase reductase Sdr
LZ753_00710	COG1272	protein, Hemolysin III
LZ753_00715	COG0463	Glycosyl transferase, family 2
LZ753_00720	COG0084	hydrolase, TatD family'
LZ753_00750	COG0330	HflC and HflK could
LZ753_00755	COG3956	TIGRFAM MazG family protein
LZ753_00760	COG1218	3'(2'),5'-bisphosphate nucleotidase
LZ753_00765	COG0494	nUDIX hydrolase
LZ753_00775	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LZ753_00780	COG0513	Belongs to the DEAD box helicase family
LZ753_00785	COG0720	synthase
LZ753_00810	COG1981	membrane
LZ753_00845	COG0512	Glutamine amidotransferase of anthranilate synthase
LZ753_00880	COG0006	proline dipeptidase activity
LZ753_00900	COG1862	Preprotein translocase
LZ753_00905	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LZ753_00910	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LZ753_00920	COG0617	tRNA 3'-terminal CCA addition
LZ753_00960	COG0195	Participates in both transcription termination and antitermination
LZ753_00990	COG1733	regulation of RNA biosynthetic process
LZ753_00995	COG0702	epimerase
LZ753_01040	COG2086	electron transfer activity
LZ753_01070	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LZ753_01100	COG0477	Major facilitator Superfamily
LZ753_01120	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LZ753_01125	COG0671	phosphoesterase, PA-phosphatase related
LZ753_01140	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LZ753_01145	COG0628	permease
LZ753_01165	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LZ753_01170	COG1090	epimerase
LZ753_01175	COG0318	PFAM AMP-dependent synthetase and ligase
LZ753_01195	COG1049	propionate catabolic process, 2-methylcitrate cycle
LZ753_01245	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LZ753_01275	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LZ753_01295	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
LZ753_01300	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
LZ753_01305	COG1034	ATP synthesis coupled electron transport
LZ753_01340	COG1007	ATP synthesis coupled electron transport
LZ753_01345	COG1028	Short-chain dehydrogenase reductase Sdr
LZ753_01350	COG2851	Citrate transporter
LZ753_01365	COG0642	Histidine kinase
LZ753_01400	COG0280	phosphate acetyltransferase
LZ753_01400	COG0281	malic enzyme
LZ753_01410	COG0742	ribosomal rna small subunit methyltransferase
LZ753_01430	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LZ753_01450	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LZ753_01475	COG2166	iron-sulfur cluster assembly
LZ753_01500	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LZ753_01575	COG1321	iron dependent repressor
LZ753_01595	COG1946	Acyl-CoA thioesterase
LZ753_01680	COG0575	Belongs to the CDS family
LZ753_01775	COG0354	folic acid binding
LZ753_01785	COG2009	succinate dehydrogenase
LZ753_01790	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
LZ753_01800	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LZ753_01830	COG0811	peptide transport
LZ753_01880	COG3093	addiction module antidote protein HigA
LZ753_01890	COG2944	sequence-specific DNA binding
LZ753_01960	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
LZ753_01980	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LZ753_02050	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LZ753_02075	COG1024	Enoyl-CoA hydratase
LZ753_02080	COG0019	diaminopimelate decarboxylase activity
LZ753_02100	COG0494	nUDIX hydrolase
LZ753_02105	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
LZ753_02130	COG0312	modulator of DNA gyrase
LZ753_02140	COG0312	modulator of DNA gyrase
LZ753_02145	COG0583	DNA-binding transcription factor activity
LZ753_02160	COG1064	alcohol dehydrogenase
LZ753_02215	COG0356	it plays a direct role in the translocation of protons across the membrane
LZ753_02335	COG0201	protein transport
LZ753_02365	COG2960	long-chain fatty acid transporting porin activity
LZ753_02370	COG0606	chelatase, subunit chli
LZ753_02395	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
LZ753_02455	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LZ753_02460	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LZ753_02475	COG1187	pseudouridine synthase activity
LZ753_02480	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LZ753_02500	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LZ753_02505	COG0625	glutathione transferase activity
LZ753_02515	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LZ753_02520	COG1217	gtp-binding protein TYPA
LZ753_02560	COG0842	Transport permease protein
LZ753_02565	COG1131	(ABC) transporter
LZ753_02585	COG1643	Atp-dependent helicase
LZ753_02595	COG1956	GAF domain-containing protein
LZ753_02600	COG0729	surface antigen
LZ753_02605	COG2911	Protein conserved in bacteria
LZ753_02615	COG0582	viral genome integration into host DNA
LZ753_02700	COG2337	Toxic component of a toxin-antitoxin (TA) module
LZ753_02810	COG0668	transmembrane transport
LZ753_02840	COG5297	Belongs to the glycosyl hydrolase family 6
LZ753_02875	COG2733	membrane
LZ753_02880	COG1253	flavin adenine dinucleotide binding
LZ753_02945	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
LZ753_02945	COG0644	oxidoreductase
LZ753_02960	COG3218	ABC-type transport auxiliary lipoprotein component
LZ753_02960	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
LZ753_02965	COG1127	ABC transporter
LZ753_02970	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LZ753_03005	COG1077	Cell shape determining protein MreB Mrl
LZ753_03015	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
LZ753_03020	COG0768	penicillin binding
LZ753_03025	COG0772	Belongs to the SEDS family
LZ753_03035	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LZ753_03055	COG2894	cell division
LZ753_03075	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
LZ753_03090	COG2353	YceI-like domain
LZ753_03160	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
LZ753_03165	COG4208	sulfate ABC transporter
LZ753_03190	COG1846	Transcriptional regulator
LZ753_03230	COG0741	lytic transglycosylase activity
LZ753_03240	COG1999	signal sequence binding
LZ753_03265	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LZ753_03300	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LZ753_03310	COG0514	ATP-dependent DNA helicase (RecQ)
LZ753_03315	COG0783	Belongs to the Dps family
LZ753_03320	COG1643	Atp-dependent helicase
LZ753_03330	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
LZ753_03335	COG1845	cytochrome c oxidase, subunit III
LZ753_03340	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LZ753_03345	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LZ753_03350	COG0142	geranyltranstransferase activity
LZ753_03365	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LZ753_03385	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LZ753_03420	COG1137	ATPase activity
LZ753_03435	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
LZ753_03485	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LZ753_03495	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LZ753_03530	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LZ753_03560	COG0542	response to heat
LZ753_03580	COG0492	ferredoxin-NADP+ reductase activity
LZ753_03600	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LZ753_03610	COG4191	Histidine kinase
LZ753_03615	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LZ753_03620	COG1028	Short-chain dehydrogenase reductase Sdr
LZ753_03650	COG1609	Transcriptional regulator
LZ753_03655	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LZ753_03660	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LZ753_03665	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
LZ753_03675	COG0726	polysaccharide deacetylase
LZ753_03680	COG0297	glycogen (starch) synthase activity
LZ753_03700	COG0719	Fe-S assembly protein
LZ753_03705	COG0396	ATPase activity
LZ753_03710	COG0719	Fe-S assembly protein
LZ753_03715	COG1959	2 iron, 2 sulfur cluster binding
LZ753_03775	COG0308	aminopeptidase N
LZ753_03830	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LZ753_03855	COG1561	YicC-like family, N-terminal region
LZ753_03870	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LZ753_03905	COG5295	Hep Hag repeat protein
LZ753_03910	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LZ753_03915	COG1459	type II secretion system
LZ753_03920	COG2165	general secretion pathway protein
LZ753_03925	COG4970	Tfp pilus assembly protein FimT
LZ753_03930	COG2165	general secretion pathway protein
LZ753_03935	COG4795	General secretion pathway protein
LZ753_03940	COG3156	type II secretion system protein K
LZ753_03945	COG3166	PFAM Fimbrial assembly family protein
LZ753_03960	COG1450	Type ii and iii secretion system protein
LZ753_03975	COG3634	alkyl hydroperoxide reductase activity
LZ753_03980	COG0583	DNA-binding transcription factor activity
LZ753_04040	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
LZ753_04065	COG0567	Dehydrogenase, E1 component
LZ753_04070	COG2850	peptidyl-arginine hydroxylation
LZ753_04085	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
LZ753_04175	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LZ753_04180	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LZ753_04185	COG2902	Dehydrogenase
LZ753_04225	COG2925	Exonuclease
LZ753_04235	COG0025	NhaP-type Na H and K H
LZ753_04255	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LZ753_04280	COG0006	proline dipeptidase activity
LZ753_04290	COG0778	Nitroreductase
LZ753_04325	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LZ753_04365	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LZ753_04375	COG0557	exoribonuclease II activity
LZ753_04385	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LZ753_04400	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
LZ753_04405	COG1289	transmembrane transporter activity
LZ753_04425	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
LZ753_04435	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LZ753_04450	COG0596	Alpha beta hydrolase
LZ753_04455	COG0727	PFAM Uncharacterised protein family (UPF0153)
LZ753_04500	COG0840	transmembrane signaling receptor activity
LZ753_04505	COG0643	Histidine kinase
LZ753_04505	COG0784	Response regulator, receiver
LZ753_04505	COG2198	Histidine kinase
LZ753_04535	COG0285	dihydrofolate synthase activity
LZ753_04545	COG0339	signal peptide processing
LZ753_04565	COG1301	dicarboxylic acid transport
LZ753_04570	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LZ753_04580	COG2091	lysine biosynthetic process via aminoadipic acid
LZ753_04625	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LZ753_04665	COG0512	Glutamine amidotransferase of anthranilate synthase
LZ753_04665	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LZ753_04675	COG0084	hydrolase, TatD family'
LZ753_04695	COG0552	protein localization to endoplasmic reticulum
LZ753_04740	COG0824	Thioesterase
LZ753_04765	COG2885	chlorophyll binding
LZ753_04775	COG0602	queuosine metabolic process
LZ753_04795	COG0386	Belongs to the glutathione peroxidase family
LZ753_04815	COG0406	alpha-ribazole phosphatase activity
LZ753_04990	COG0675	Transposase, IS605 OrfB family
LZ753_05150	COG2369	cell adhesion
LZ753_05200	COG0582	viral genome integration into host DNA
LZ753_05205	COG3567	Phage-associated protein, HI1409 family
LZ753_05210	COG5410	chromosome segregation
LZ753_05235	COG3772	lysozyme
LZ753_05270	COG3617	BRO family, N-terminal domain
LZ753_05355	COG5532	Uncharacterized conserved protein (DUF2303)
LZ753_05380	COG0629	single-stranded DNA binding
LZ753_05390	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
LZ753_05395	COG3852	Histidine kinase
LZ753_05400	COG2204	response regulator
LZ753_05415	COG0004	ammonium transporteR
LZ753_05420	COG0347	Belongs to the P(II) protein family
LZ753_05425	COG0174	glutamine synthetase
LZ753_05435	COG2353	YceI-like domain
LZ753_05490	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
LZ753_05495	COG1764	response to oxidative stress
LZ753_05500	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LZ753_05545	COG1399	metal-binding, possibly nucleic acid-binding protein
LZ753_05555	COG0714	Associated with various cellular activities
LZ753_05575	COG0537	adenosine 5'-monophosphoramidase activity
LZ753_05590	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LZ753_05635	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LZ753_05660	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
LZ753_05660	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
LZ753_05715	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LZ753_05730	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
LZ753_05745	COG0251	oxidation-reduction process
LZ753_05810	COG3077	Addiction module antitoxin, RelB DinJ family
LZ753_05815	COG3041	Addiction module toxin RelE StbE family
LZ753_05885	COG3772	lysozyme
LZ753_05950	COG4197	protein conserved in bacteria, prophage-related
LZ753_06020	COG3617	BRO family, N-terminal domain
LZ753_06060	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
LZ753_06065	COG0392	lysyltransferase activity
LZ753_06065	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LZ753_06075	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LZ753_06085	COG0463	Glycosyl transferase, family 2
LZ753_06130	COG3275	phosphorelay sensor kinase activity
LZ753_06135	COG0400	carboxylic ester hydrolase activity
LZ753_06155	COG2226	methyltransferase
LZ753_06175	COG2027	D-alanyl-D-alanine carboxypeptidase
LZ753_06180	COG2027	D-alanyl-D-alanine carboxypeptidase
LZ753_06220	COG0386	Belongs to the glutathione peroxidase family
LZ753_06225	COG1131	(ABC) transporter
LZ753_06255	COG3657	addiction module killer protein
LZ753_06260	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LZ753_06325	COG0675	Transposase, IS605 OrfB family
LZ753_06370	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
LZ753_06375	COG0488	(ABC) transporter
LZ753_06385	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
LZ753_06395	COG4651	solute:proton antiporter activity
LZ753_06395	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LZ753_06455	COG0859	PFAM glycosyl transferase family 9
LZ753_06470	COG0631	protein serine/threonine phosphatase activity
LZ753_06475	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LZ753_06510	COG2183	response to ionizing radiation
LZ753_06525	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
LZ753_06530	COG3118	belongs to the thioredoxin family
LZ753_06575	COG2951	lytic endotransglycosylase activity
LZ753_06580	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
LZ753_06720	COG0277	FAD linked oxidase domain protein
LZ753_06725	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LZ753_06730	COG0531	amino acid
LZ753_06735	COG0531	amino acid
LZ753_06815	COG0460	homoserine dehydrogenase
LZ753_06815	COG0527	aspartate kinase activity
LZ753_06835	COG1686	Belongs to the peptidase S11 family
LZ753_06860	COG4953	penicillin-binding protein 1C
LZ753_06885	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LZ753_06955	COG1506	peptidase
LZ753_06955	COG0823	Involved in the tonB-independent uptake of proteins
LZ753_06960	COG1297	OPT oligopeptide transporter protein
LZ753_06990	COG0676	glucose-6-phosphate 1-epimerase activity
LZ753_07000	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LZ753_07005	COG1335	isochorismatase
LZ753_07010	COG0318	PFAM AMP-dependent synthetase and ligase
LZ753_07020	COG0463	Glycosyl transferase, family 2
LZ753_07035	COG1192	Involved in chromosome partitioning
LZ753_07110	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LZ753_07155	COG0489	protein tyrosine kinase activity
LZ753_07165	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LZ753_07265	COG1605	Chorismate mutase
LZ753_07265	COG0077	Prephenate dehydratase
LZ753_07280	COG1668	transmembrane transport
LZ753_07285	COG4555	ABC transporter
LZ753_07310	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
LZ753_07320	COG1605	Chorismate mutase
LZ753_07320	COG0287	Prephenate dehydrogenase
LZ753_07355	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LZ753_07380	COG1278	Cold shock
LZ753_07390	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
LZ753_07400	COG2954	triphosphatase activity
LZ753_07415	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
LZ753_07420	COG0438	transferase activity, transferring glycosyl groups
LZ753_07430	COG0438	transferase activity, transferring glycosyl groups
LZ753_07495	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LZ753_07500	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LZ753_07515	COG1064	alcohol dehydrogenase
LZ753_07530	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
LZ753_07540	COG0436	Aminotransferase
LZ753_07630	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
LZ753_07630	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LZ753_07685	COG0196	riboflavin kinase activity
LZ753_07690	COG0728	peptidoglycan biosynthetic process
LZ753_07695	COG0268	Binds directly to 16S ribosomal RNA
LZ753_07745	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LZ753_07760	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
LZ753_07815	COG0395	ABC-type sugar transport system, permease component
LZ753_07820	COG1175	transmembrane transport
LZ753_07870	COG0436	Aminotransferase
LZ753_07930	COG5434	Belongs to the glycosyl hydrolase 28 family
LZ753_07955	COG0402	S-adenosylhomocysteine deaminase activity
LZ753_07965	COG1509	lysine 2,3-aminomutase activity
LZ753_08000	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LZ753_08005	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LZ753_08020	COG1028	Short-chain dehydrogenase reductase Sdr
LZ753_08070	COG0142	geranyltranstransferase activity
LZ753_08095	COG1301	dicarboxylic acid transport
LZ753_08105	COG0791	NLP P60 protein
LZ753_08110	COG0791	NLP P60 protein
LZ753_08120	COG2311	Membrane
LZ753_08130	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LZ753_08185	COG0352	thiamine-phosphate diphosphorylase activity
LZ753_08185	COG0351	phosphomethylpyrimidine kinase
LZ753_08195	COG1324	tolerance protein
LZ753_08235	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LZ753_08240	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
LZ753_08255	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LZ753_08275	COG4774	siderophore transport
LZ753_08300	COG1477	protein flavinylation
LZ753_08305	COG1555	photosystem II stabilization
LZ753_08310	COG3178	'Phosphotransferase
LZ753_08315	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LZ753_08325	COG0628	permease
LZ753_08345	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LZ753_08370	COG3590	peptidase
LZ753_08420	COG0805	protein transport
LZ753_08430	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LZ753_08430	COG0519	Catalyzes the synthesis of GMP from XMP
LZ753_08440	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
LZ753_08455	COG3107	peptidoglycan biosynthetic process
LZ753_08480	COG2878	Part of a membrane complex involved in electron transport
LZ753_08555	COG0629	single-stranded DNA binding
LZ753_08585	COG0827	DNA restriction-modification system
LZ753_08590	COG0827	DNA restriction-modification system
LZ753_08630	COG4968	Prepilin-type N-terminal cleavage methylation domain
LZ753_08635	COG1611	Belongs to the LOG family
LZ753_08640	COG4943	cyclic-guanylate-specific phosphodiesterase activity
LZ753_08645	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LZ753_08655	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LZ753_08685	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LZ753_08700	COG0330	HflC and HflK could
LZ753_08705	COG0330	HflC and HflK could
LZ753_08710	COG0604	alcohol dehydrogenase
LZ753_08740	COG1183	phosphatidylcholine synthase activity
LZ753_08760	COG0668	transmembrane transport
LZ753_08765	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LZ753_08780	COG1610	YqeY-like protein
LZ753_08790	COG0358	DNA primase activity
LZ753_08825	COG1074	ATP-dependent DNA helicase activity
LZ753_08830	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
LZ753_08835	COG1127	ABC transporter
LZ753_08840	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LZ753_08860	COG2853	Lipoprotein
LZ753_08870	COG1116	anion transmembrane transporter activity
LZ753_08880	COG0531	amino acid
LZ753_08885	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LZ753_08890	COG0861	Integral membrane protein TerC family
LZ753_08920	COG2193	ferroxidase activity
LZ753_09010	COG2194	sulfuric ester hydrolase activity
LZ753_09050	COG0667	Aldo Keto reductase
LZ753_09055	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LZ753_09065	COG0305	Participates in initiation and elongation during chromosome replication
LZ753_09095	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LZ753_09105	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LZ753_09110	COG0277	FAD linked oxidase domain protein
LZ753_09125	COG4206	TonB-dependent receptor
LZ753_09225	COG3617	BRO family, N-terminal domain
LZ753_09295	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LZ753_09315	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
LZ753_09340	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LZ753_09340	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LZ753_09360	COG0488	(ABC) transporter
LZ753_09370	COG3011	Protein conserved in bacteria
LZ753_09400	COG1918	ferrous iron import across plasma membrane
LZ753_09400	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
LZ753_09410	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LZ753_09435	COG0758	DNA mediated transformation
LZ753_09480	COG2969	positive regulation of protein catabolic process
LZ753_09485	COG0625	glutathione transferase activity
LZ753_09490	COG2857	Cytochrome c1
LZ753_09495	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
LZ753_09500	COG0723	plastoquinol--plastocyanin reductase activity
LZ753_09505	COG0741	lytic transglycosylase activity
LZ753_09515	COG1702	phosphate starvation-inducible protein PhoH
LZ753_09530	COG4535	Mg2 and Co2 transporter CorC
LZ753_09540	COG0598	Magnesium transport protein CorA
LZ753_09620	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LZ753_09630	COG1199	ATP-dependent helicase activity
LZ753_09640	COG0288	reversible hydration of carbon dioxide
LZ753_09665	COG2011	ABC-type metal ion transport system permease component
LZ753_09685	COG0508	dehydrogenase complex catalyzes the overall conversion of
LZ753_09690	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LZ753_09705	COG0626	cystathionine gamma-synthase activity
LZ753_09710	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LZ753_09715	COG0739	heme binding
LZ753_09735	COG1238	metal cluster binding
LZ753_09775	COG1388	LysM domain
LZ753_09775	COG3858	chitin binding
LZ753_09780	COG3525	Glycosyl hydrolase, family 20, catalytic domain
LZ753_09790	COG1472	Belongs to the glycosyl hydrolase 3 family
LZ753_09805	COG3537	Alpha-1,2-mannosidase
LZ753_09830	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LZ753_09835	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LZ753_09880	COG0469	pyruvate kinase activity
LZ753_09900	COG0735	belongs to the Fur family
LZ753_09945	COG4305	rare lipoprotein A
LZ753_09955	COG0739	heme binding
LZ753_09970	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LZ753_09980	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
LZ753_10010	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LZ753_10025	COG3116	cell division
LZ753_10040	COG0471	metal ion transport
LZ753_10040	COG3273	potassium ion transport
LZ753_10095	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LZ753_10155	COG0860	N-Acetylmuramoyl-L-alanine amidase
LZ753_10160	COG0802	atpase or kinase
LZ753_10165	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LZ753_10165	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LZ753_10265	COG0745	RESPONSE REGULATOR receiver
LZ753_10270	COG0642	Histidine kinase
LZ753_10280	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
LZ753_10325	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
LZ753_10335	COG2831	hemolysin activation secretion protein
LZ753_10360	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
LZ753_10400	COG0316	Belongs to the HesB IscA family
LZ753_10440	COG0697	spore germination
LZ753_10445	COG0671	phosphoesterase, PA-phosphatase related
LZ753_10460	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
LZ753_10480	COG1132	(ABC) transporter
LZ753_10485	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
LZ753_10490	COG1538	Outer membrane efflux protein
LZ753_10515	COG0745	RESPONSE REGULATOR receiver
LZ753_10520	COG4783	chaperone-mediated protein folding
LZ753_10530	COG0473	3-isopropylmalate dehydrogenase activity
LZ753_10540	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LZ753_10545	COG3083	sulfuric ester hydrolase activity
LZ753_10550	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
LZ753_10575	COG0564	pseudouridine synthase activity
LZ753_10580	COG1530	ribonuclease E activity
LZ753_10585	COG2197	response regulator
LZ753_10600	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LZ753_10615	COG0488	(ABC) transporter
LZ753_10630	COG1278	Cold shock
LZ753_10730	COG0012	GTP binding
LZ753_10825	COG2095	MarC family integral membrane protein
LZ753_10835	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
LZ753_10860	COG2132	Multicopper oxidase
LZ753_10870	COG0210	DNA helicase
LZ753_10880	COG0616	signal peptide processing
LZ753_10900	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LZ753_10920	COG2201	protein-glutamate methylesterase activity
LZ753_10925	COG2177	Part of the ABC transporter FtsEX involved in
LZ753_10930	COG2884	Cell division ATP-binding protein ftsE
LZ753_10940	COG3118	belongs to the thioredoxin family
LZ753_10945	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
LZ753_10960	COG0793	Belongs to the peptidase S41A family
LZ753_10965	COG4942	peptidase
LZ753_10980	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
LZ753_10985	COG0493	'glutamate synthase
LZ753_10990	COG0067	glutamate synthase
LZ753_10990	COG0069	glutamate synthase activity
LZ753_10990	COG0070	glutamate synthase
LZ753_11040	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
LZ753_11090	COG4942	peptidase
LZ753_11240	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LZ753_11245	COG3657	addiction module killer protein
LZ753_11340	COG3210	domain, Protein
LZ753_11420	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LZ753_11420	COG0551	DNA topoisomerase type I activity
LZ753_11555	COG1475	DNA binding
LZ753_11565	COG0629	single-stranded DNA binding
LZ753_11580	COG1192	Involved in chromosome partitioning
LZ753_11670	COG3451	type IV secretory pathway VirB4
LZ753_11830	COG0675	Transposase, IS605 OrfB family
LZ753_11850	COG0629	single-stranded DNA binding
LZ753_11860	COG4962	Type ii secretion system protein e